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Circulation. Heart Failure

journal
https://www.readbyqxmd.com/read/27895070/i-forgot-memory-and-medication-adherence-in-heart-failure
#1
EDITORIAL
Barbara Riegel
No abstract text is available yet for this article.
December 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27895069/association-between-poorer-cognitive-function-and-reduced-objectively-monitored-medication-adherence-in-patients-with-heart-failure
#2
Mary A Dolansky, Misty A W Hawkins, Julie T Schaefer, Abdus Sattar, John Gunstad, Joseph D Redle, Richard Josephson, Shirley M Moore, Joel W Hughes
BACKGROUND: Subclinical cognitive impairment is prevalent in heart failure (HF); however, its role in important clinical outcomes, such as HF treatment adherence, is unclear. Given the complex polypharmacy in HF treatment, cognitive deficits may be important in predicting medication management. Thus, the objective of the current study was to examine the impact of cognitive function on medication adherence among community-dwelling patients with HF using objective assessments. METHODS AND RESULTS: A prospective observational cohort design of 309 community-dwelling patients with HF (59...
December 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27864304/constrictive-pericarditis-and-protein-losing-enteropathy-is-extremely-severe-hypoalbuminemia-reversible-by-pericardiectomy
#3
Hidenori Moriyama, Takashi Kohno, Takahiko Nishiyama, Osamu Hattori, Yuichiro Maekawa, Kosuke Yoshida, Mitsushige Murata, Kazuma Okamoto, Motoaki Sano, Hideyuki Shimizu, Keiichi Fukuda
No abstract text is available yet for this article.
December 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27864303/diagnosis-of-left-ventricular-assist-device-outflow-graft-obstruction-using-intravascular-ultrasound
#4
Hellmuth R Muller Moran, Malek Kass, Amir Ravandi, Shelley Zieroth, S Allan Schaffer, Francisco J Cordova, Zlatko I Pozeg, Rakesh C Arora, Rohit K Singal
No abstract text is available yet for this article.
December 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27852654/cobalt-cardiomyopathy-a-critical-reappraisal-in-light-of-a-recent-resurgence
#5
Milton Packer
Cobalt can cause a distinctive, rapidly progressive and reversible depression of cardiac systolic function, which is readily distinguished from other causes of cardiomyopathy. Patients present with the subacute onset of severe heart failure, which is accompanied by hypotension and cyanosis, pericardial effusion, low voltage on the electrocardiogram, marked elevation of serum enzymes, and lactic acidosis. They typically have a history of lethargy, anorexia, and weight loss in the months preceding the illness and exhibit other evidence of cobalt's effects on the body (eg, polycythemia and goiter)...
December 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27852653/one-year-outcomes-after-transcatheter-insertion-of-an-interatrial-shunt-device-for-the-management-of-heart-failure-with-preserved-ejection-fraction
#6
David M Kaye, Gerd Hasenfuß, Petr Neuzil, Martijn C Post, Robert Doughty, Jean-Noël Trochu, Adam Kolodziej, Ralf Westenfeld, Martin Penicka, Mark Rosenberg, Antony Walton, David Muller, Darren Walters, Jorg Hausleiter, Philip Raake, Mark C Petrie, Martin Bergmann, Guillaume Jondeau, Ted Feldman, Dirk J van Veldhuisen, Piotr Ponikowski, Frank E Silvestry, Dan Burkhoff, Christopher Hayward
BACKGROUND: Heart failure with preserved ejection fraction has a complex pathophysiology and remains a therapeutic challenge. Elevated left atrial pressure, particularly during exercise, is a key contributor to morbidity and mortality. Preliminary analyses have demonstrated that a novel interatrial septal shunt device that allows shunting to reduce the left atrial pressure provides clinical and hemodynamic benefit at 6 months. Given the chronicity of heart failure with preserved ejection fraction, evidence of longer-term benefit is required...
December 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27834199/the-continuing-quest-to-identify-ambulatory-patients-with-advanced-heart-failure-who-benefit-from-left-ventricular-assist-device-therapy
#7
EDITORIAL
Omar Wever-Pinzon, Stavros G Drakos
No abstract text is available yet for this article.
November 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27834198/intermacs-interagency-registry-for-mechanically-assisted-circulatory-support-profiling-identifies-ambulatory-patients-at-high-risk-on-medical-therapy-after-hospitalizations-for-heart-failure
#8
Garrick C Stewart, Michelle M Kittleson, Parag C Patel, Jennifer A Cowger, Chetan B Patel, Maria M Mountis, Frances L Johnson, Maya E Guglin, J Eduardo Rame, Jeffrey J Teuteberg, Lynne W Stevenson
BACKGROUND: INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) profiles provide important prognostic information for patients with advanced heart failure (HF) receiving mechanical support. The value of INTERMACS profiling has not been shown for patients followed on medical therapy for advanced HF at centers that also offer mechanical circulatory support. METHODS AND RESULTS: This prospective, observational study enrolled 166 patients with chronic New York Heart Association class III-IV HF, ejection fraction ≤30%, and ≥1 HF hospitalization in the previous year, excluding patients listed for transplant or receiving chronic intravenous inotropic therapy...
November 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27810863/hypoxia-inducible-factor-1%C3%AE-mediates-increased-sympathoexcitation-via-glutamatergic-n-methyl-d-aspartate-receptors-in-the-paraventricular-nucleus-of-rats-with-chronic-heart-failure
#9
Neeru M Sharma, Craig J Cunningham, Hong Zheng, Xuefei Liu, Kaushik P Patel
BACKGROUND: Increased sympathetic outflow is a major contributor to the progression of chronic heart failure (CHF). Potentiation of glutamatergic tone has been causally related to the sympathoexcitation in CHF. Specifically, an increase in the N-methyl-d-aspartate-type 1 receptor (NMDA-NR1) expression within the paraventricular nucleus (PVN) is critically linked to the increased sympathoexcitation during CHF. However, the molecular mechanism(s) for the upregulation of NMDA-NR1 remains unexplored...
November 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27810862/dual-endothelin-a-endothelin-b-receptor-blockade-and-cardiac-remodeling-in-heart-failure-with-preserved-ejection-fraction
#10
Maria Valero-Munoz, Shanpeng Li, Richard M Wilson, Batbold Boldbaatar, Marc Iglarz, Flora Sam
BACKGROUND: Despite the increasing prevalence of heart failure with preserved ejection fraction (HFpEF) in humans, there remains no evidence-based therapies for HFpEF. Endothelin-1 (ET-1) antagonists are a possibility because elevated ET-1 levels are associated with adverse cardiovascular effects, such as arterial and pulmonary vasoconstriction, impaired left ventricular (LV) relaxation, and stimulation of LV hypertrophy. LV hypertrophy is a common phenotype in HFpEF, particularly when associated with hypertension...
November 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27806986/first-in-human-experience-with-transcatheter-mitral-valve-in-valve-implantation-during-left-ventricular-assist-device-placement
#11
Gabriela Orasanu, Sadeer G Al-Kindi, Monique R Robinson, Guilherme H Oliveira, Mahazarin Ginwalla, Chantal Elamm, Michael Zacharias, Mahmoud Farhoud, Benjamin Medalion, Salil V Deo, Soon J Park, Guilherme F Attizzani, Basar Sareyyupoglu
No abstract text is available yet for this article.
November 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27780836/variation-in-hospital-use-and-outcomes-associated-with-pulmonary-artery-catheterization-in-heart-failure-in-the-united-states
#12
Rohan Khera, Ambarish Pandey, Nilay Kumar, Rajeev Singh, Shah Bano, Harsh Golwala, Dharam J Kumbhani, Saket Girotra, Gregg C Fonarow
BACKGROUND: There has been an increase in the use of pulmonary artery (PA) catheters in heart failure (HF) in the United States in recent years. However, patterns of hospital use and trends in patient outcomes are not known. METHODS AND RESULTS: In the National Inpatient Sample 2001 to 2012, using International Classification of Diseases-Ninth Revision codes, we identified 11 888 525 adult (≥18 years) HF hospitalizations nationally, of which an estimated 75 209 (SE 0...
November 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27756791/exploring-new-endpoints-for-patients-with-heart-failure-with-preserved-ejection-fraction
#13
Javed Butler, Carine E Hamo, James E Udelson, Bertram Pitt, Clyde Yancy, Sanjiv J Shah, Patrice Desvigne-Nickens, Harold S Bernstein, Richard L Clark, Christophe Depre, Wilfried Dinh, Andrew Hamer, Patricia Kay-Mugford, Frank Kramer, Martin Lefkowitz, Kelly Lewis, Juan Maya, Simon Maybaum, Mahesh J Patel, Pia S Pollack, Lothar Roessig, Sarit Rotman, Afshin Salsali, J Jason Sims, Michele Senni, Giuseppe Rosano, Preston Dunnmon, Norman Stockbridge, Stefan D Anker, Michael R Zile, Mihai Gheorghiade
The epidemiological, clinical, and societal implications of the heart failure (HF) epidemic cannot be overemphasized. Approximately half of all HF patients have HF with preserved ejection fraction (HFpEF). HFpEF is largely a syndrome of the elderly, and with aging of the population, the proportion of patients with HFpEF is expected to grow. Currently, there is no drug known to improve mortality or hospitalization risk for these patients. Besides mortality and hospitalization, it is imperative to realize that patients with HFpEF have significant impairment in their functional capacity and their quality of life on a daily basis, underscoring the need for these parameters to ideally be incorporated within a regulatory pathway for drug approval...
November 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27758812/palliative-care-throughout-the-journey-of-life-with-a-left-ventricular-assist-device
#14
Winifred Teuteberg, Mathew Maurer
No abstract text is available yet for this article.
October 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27758811/left-atrial-remodeling-and-atrioventricular-coupling-in-a-canine-model-of-early-heart-failure-with-preserved-ejection-fraction
#15
Rosita Zakeri, Gilles Moulay, Qiang Chai, Ozgur Ogut, Saad Hussain, Hiroyuki Takahama, Tong Lu, Xiao-Li Wang, Wolfgang A Linke, Hon-Chi Lee, Margaret M Redfield
BACKGROUND: Left atrial (LA) compliance and contractility influence left ventricular stroke volume. We hypothesized that diminished LA compliance and contractile function occur early during the development of heart failure with preserved ejection fraction (HFpEF) and impair overall cardiac performance. METHODS AND RESULTS: Cardiac magnetic resonance imaging, echocardiography, left ventricular and LA pressure-volume studies, and tissue analyses were performed in a model of early HFpEF (elderly dogs, renal wrap-induced hypertension, exogenous aldosterone; n=9) and young control dogs (sham surgery; n=13)...
October 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27758810/impact-of-socioeconomic-status-on-patients-supported-with-a-left-ventricular-assist-device-an-analysis-of-the-unos-database-united-network-for-organ-sharing
#16
Kevin J Clerkin, Arthur Reshad Garan, Brian Wayda, Raymond C Givens, Melana Yuzefpolskaya, Shunichi Nakagawa, Koji Takeda, Hiroo Takayama, Yoshifumi Naka, Donna M Mancini, Paolo C Colombo, Veli K Topkara
BACKGROUND: Low socioeconomic status (SES) is a known risk factor for heart failure, mortality among those with heart failure, and poor post heart transplant (HT) outcomes. This study sought to determine whether SES is associated with decreased waitlist survival while on left ventricular assist device (LVADs) support and after HT. METHODS AND RESULTS: A total of 3361 adult patients bridged to primary HT with an LVAD between May 2004 and April 2014 were identified in the UNOS database (United Network for Organ Sharing)...
October 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27758809/dying-with-a-left-ventricular-assist-device-as-destination-therapy
#17
Shannon M Dunlay, Jacob J Strand, Sara E Wordingham, John M Stulak, Angela J Luckhardt, Keith M Swetz
BACKGROUND: Despite the ability of left ventricular assist device as destination therapy (DT-LVAD) to prolong survival for many patients with advanced heart failure, little is known about the eventual end-of-life care that patients with DT-LVAD receive. METHODS AND RESULTS: All patients undergoing DT-LVAD at the Mayo Clinic in Rochester, Minnesota, from January 1, 2007, to September 30, 2014, who subsequently died before July 1, 2015, were included. Information about end-of-life care was obtained from documentation in the electronic medical record...
October 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27729391/impact-of-statin-use-after-heart-transplantation-a-meta-analysis
#18
Ajay Vallakati, Siddharth Reddy, Mark E Dunlap, David O Taylor
BACKGROUND: Although various studies revealed the beneficial effects of statins in post-cardiac transplant patients, these were relatively small and low-powered studies. We performed a meta-analysis of published studies to evaluate the role of statins in post-cardiac transplant patients, specifically examining the effects on hemodynamically significant/fatal graft rejection, coronary vasculopathy, terminal cancer, and overall survival. METHODS AND RESULTS: We searched PubMed, Cochran CENTRAL, and Web of Science databases using the search terms "cardiac transplant" or "heart transplant," and "statin" for a literature search...
October 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27707751/dilemmas-with-race-and-heart-failure-treatment
#19
Javed Butler, Marvin A Konstam
No abstract text is available yet for this article.
October 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27707750/transforming-drug-development-in-heart-failure-navigating-the-regulatory-crossroads
#20
Muthiah Vaduganathan, Javed Butler, Mihai Gheorghiade
No abstract text is available yet for this article.
October 2016: Circulation. Heart Failure
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