journal
MENU ▼
Read by QxMD icon Read
search

Circulation. Heart Failure

journal
https://www.readbyqxmd.com/read/28500255/balancing-bleeding-and-clotting-the-known-unknowns-of-mechanically-assisted-circulation
#1
EDITORIAL
Joseph G Rogers
No abstract text is available yet for this article.
May 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28500254/increased-thromboembolic-events-with-dabigatran-compared-with-vitamin-k-antagonism-in-left-ventricular-assist-device-patients-a-randomized-controlled-pilot-trial
#2
Martin Andreas, Roxana Moayedifar, Georg Wieselthaler, Michael Wolzt, Julia Riebandt, Thomas Haberl, Philipp Angleitner, Thomas Schlöglhofer, Dominik Wiedemann, Heinrich Schima, Guenther Laufer, Daniel Zimpfer
BACKGROUND: Left ventricular assist device-supported patients are usually anticoagulated with a combination of aspirin and vitamin K antagonists. Long-term vitamin K antagonist therapy can be complicated by unstable international normalized ratio values and patient-related compliance problems. Therefore, direct thrombin inhibitors may represent an alternative to vitamin K antagonists. METHODS AND RESULTS: Thirty HeartWare ventricular assist device patients with stable renal function were planned for this prospective, randomized, open-label, single-center study...
May 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28495954/the-heavy-heart-metabolic-mechanisms-and-myocardial-mechanics
#3
EDITORIAL
Amanda R Vest, Ayan R Patel
No abstract text is available yet for this article.
May 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28495953/cardiometabolic-traits-and-systolic-mechanics-in-the-community
#4
Jennifer E Ho, Elizabeth L McCabe, Thomas J Wang, Martin G Larson, Daniel Levy, Connie Tsao, Jayashri Aragam, Gary F Mitchell, Emelia J Benjamin, Ramachandran S Vasan, Susan Cheng
BACKGROUND: Obesity and cardiometabolic dysfunction are associated with increased risk of heart failure and other cardiovascular diseases. We sought to examine the association of cardiometabolic traits with left ventricular (LV) cardiac mechanics. We hypothesized that specific obesity-related phenotypes are associated with distinct aspects of LV strain. METHODS AND RESULTS: We evaluated the associations of obesity-related phenotypes, including central adiposity, diabetes mellitus, insulin resistance, and circulating adipokine concentrations with echocardiographic measures of LV mechanical function among participants of the Framingham Heart Study Offspring and Third Generation cohorts...
May 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28490430/percutaneous-mitral-valve-edge-to-edge-repair-assisted-by-hemodynamic-support-devices-a-case-series-of-bailout-procedures
#5
Peter Seizer, David Schibilsky, Reinhard Sauter, Jürgen Schreieck, Henning Lausberg, Tobias Walker, Meinrad Gawaz, Harald F Langer, Christian Schlensak
No abstract text is available yet for this article.
May 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28490429/closing-the-care-gap-a-primer-on-quality-improvement-for-heart-failure-clinicians
#6
REVIEW
Yasbanoo Moayedi, Toni Schofield, Edward Etchells, Samuel A Silver, Jeremy Kobulnik, Rory McQuillan, Chaim Bell, Meredith Linghorne, Heather J Ross
Quality improvement (QI) initiatives have become an integral part of patient-centered care. In this primer, we outline 6 steps for initiating, implementing, and monitoring improvement in heart failure care. These steps include acknowledging that improvement is needed and setting a culture for improvement; forming a QI team; understanding the local problem; generating improvement strategies that will fit with the local problem; monitoring; testing; and refining improvements, analysis of data, and interpretation of run charts...
May 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28487343/stiff-left-atrial-syndrome-after-multiple-percutaneous-catheter-ablations-role-for-invasive-hemodynamic-exercise-testing
#7
Marcus A Urey, Douglas Darden, Douglas Stoller, Mark H Drazner, Vernon Horn, Satyam Sarma, Benjamin D Levine
No abstract text is available yet for this article.
May 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28487342/calcium-calmodulin-dependent-protein-kinase-ii-activity-persists-during-chronic-%C3%AE-adrenoceptor-blockade-in-experimental-and-human-heart-failure
#8
Matthias Dewenter, Stefan Neef, Christiane Vettel, Simon Lämmle, Christina Beushausen, Laura C Zelarayan, Sylvia Katz, Albert von der Lieth, Stefanie Meyer-Roxlau, Silvio Weber, Thomas Wieland, Samuel Sossalla, Johannes Backs, Joan H Brown, Lars S Maier, Ali El-Armouche
BACKGROUND: Considerable evidence suggests that calcium/calmodulin-dependent protein kinase II (CaMKII) overactivity plays a crucial role in the pathophysiology of heart failure (HF), a condition characterized by excessive β-adrenoceptor (β-AR) stimulation. Recent studies indicate a significant cross talk between β-AR signaling and CaMKII activation presenting CaMKII as a possible downstream mediator of detrimental β-AR signaling in HF. In this study, we investigated the effect of chronic β-AR blocker treatment on CaMKII activity in human and experimental HF...
May 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28476756/indie-hfpef-inorganic-nitrite-delivery-to-improve-exercise-capacity-in-heart-failure-with-preserved-ejection-fraction-rationale-and-design
#9
Yogesh N V Reddy, Gregory D Lewis, Sanjiv J Shah, Martin LeWinter, Marc Semigran, Victor G Davila-Roman, Kevin Anstrom, Adrian Hernandez, Eugene Braunwald, Margaret M Redfield, Barry A Borlaug
Approximately half of patients with heart failure have preserved ejection fraction. There is no proven treatment that improves outcome. The pathophysiology of heart failure with preserved ejection fraction is complex and includes left ventricular systolic and diastolic dysfunction, pulmonary vascular disease, endothelial dysfunction, and peripheral abnormalities. Multiple lines of evidence point to impaired nitric oxide (NO)-cGMP bioavailability as playing a central role in each of these abnormalities. In contrast to traditional organic nitrate therapies, an alternative strategy to restore NO-cGMP signaling is via inorganic nitrite...
May 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28465311/accuracy-of-seattle-heart-failure-model-and-heartmate-ii-risk-score-in-non-inotrope-dependent-advanced-heart-failure-patients-insights-from-the-roadmap-study-risk-assessment-and-comparative-effectiveness-of-left-ventricular-assist-device-and-medical-management
#10
REVIEW
David E Lanfear, Wayne C Levy, Josef Stehlik, Jerry D Estep, Joseph G Rogers, Keyur B Shah, Andrew J Boyle, Joyce Chuang, David J Farrar, Randall C Starling
BACKGROUND: Timing of left ventricular assist device (LVAD) implantation in advanced heart failure patients not on inotropes is unclear. Relevant prediction models exist (SHFM [Seattle Heart Failure Model] and HMRS [HeartMate II Risk Score]), but use in this group is not established. METHODS AND RESULTS: ROADMAP (Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients) is a prospective, multicenter, nonrandomized study of 200 advanced heart failure patients not on inotropes who met indications for LVAD implantation, comparing the effectiveness of HeartMate II support versus optimal medical management...
May 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28455293/true-anemia-red-blood-cell-volume-deficit-in-heart-failure-a-systematic-review
#11
REVIEW
David Montero, Carsten Lundby, Frank Ruschitzka, Andreas J Flammer
BACKGROUND: Anemia in heart failure (HF) is commonly diagnosed according to hemoglobin concentration [Hb], hence may be the result of hemodilution or true red blood cell volume (RBCV) deficit. Whether true (nonhemodilutional) anemia in HF can or cannot be generally inferred by [Hb] measurements and clinical correlates remains unclear. The purpose of this study was to systematically review the literature and investigate the status and correlates of RBCV in patients with HF. METHODS AND RESULTS: MEDLINE, Scopus, and Web of Science were searched since their inceptions until April 2016 for articles directly reporting or allowing the calculation of intravascular volumes (RBCV, plasma volume) in patients with HF according to the International Council for Standardization in Hematology...
May 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28404627/multiphasic-regulation-of-systemic-and-peripheral-organ-metabolic-responses-to-cardiac-hypertrophy
#12
Chong Wee Liew, Shanshan Xu, Xuerong Wang, Maximilian McCann, Hyerim Whang Kong, Andrew C Carley, Jingbo Pang, Giamila Fantuzzi, J Michael O'Donnell, E Douglas Lewandowski
BACKGROUND: Reduced fat oxidation in hypertrophied hearts coincides with a shift of carnitine palmitoyl transferase I from muscle to increased liver isoforms. Acutely increased carnitine palmitoyl transferase I in normal rodent hearts has been shown to recapitulate the reduced fat oxidation and elevated atrial natriuretic peptide message of cardiac hypertrophy. METHODS AND RESULTS: Because of the potential for reduced fat oxidation to affect cardiac atrial natriuretic peptide, and thus, induce adipose lipolysis, we studied peripheral and systemic metabolism in male C57BL/6 mice model of transverse aortic constriction in which left ventricular hypertrophy occurred by 2 weeks without functional decline until 16 weeks (ejection fraction, -45...
April 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28404626/adenosine-formed-by-cd73-on-t-cells-inhibits-cardiac-inflammation-and-fibrosis-and-preserves-contractile-function-in-transverse-aortic-constriction-induced-heart-failure
#13
Christine Quast, Christina Alter, Zhaoping Ding, Nadine Borg, Jürgen Schrader
BACKGROUND: Structural damage during heart failure development leads to increased infiltration of leukocytes. Because purinergic signaling on immune cells may impact on the inflammatory response, we evaluated the role of ecto-5'-nucleotidase (CD73) on the development of heart failure after transverse aortic constriction (TAC) using global and T-cell-specific CD73(-)(/-) mice. METHODS AND RESULTS: Leukocytes infiltrating the failing heart were analyzed by a multistep enzymatic procedure over a period of 16 weeks using fluorescence-activated cell sorting...
April 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28396502/pericardiectomy-to-treat-heart-failure-with-preserved-ejection-fraction-unrestrained-enthusiasm
#14
EDITORIAL
Martin M LeWinter
No abstract text is available yet for this article.
April 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28396501/mechanism-of-progressive-heart-failure-and-significance-of-pulmonary-hypertension-in-obstructive-hypertrophic-cardiomyopathy
#15
Michele Covella, Ethan J Rowin, Nicholas S Hill, Ioana R Preston, Alberto Milan, Alexander R Opotowsky, Barry J Maron, Martin S Maron, Bradley A Maron
BACKGROUND: There are limited data on the prevalence, pathophysiology, and management implications of pulmonary hypertension in patients with obstructive hypertrophic cardiomyopathy and advanced heart failure. METHODS AND RESULTS: To assess the clinical significance of measured cardiopulmonary hemodynamics in hypertrophic cardiomyopathy patients with heart failure, we retrospectively assessed right heart catheterization data in 162 consecutive patients with outflow tract gradients (median [interquartile range], 90 mm Hg [70-110 mm Hg]), 59±11 years old, and 49% men, predominately New York Heart Association class III/IV status...
April 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28396500/percutaneous-pericardial-resection-a-novel-potential-treatment-for-heart-failure-with-preserved-ejection-fraction
#16
Barry A Borlaug, Rickey E Carter, Vojtech Melenovsky, Christopher V DeSimone, Prakriti Gaba, Ammar Killu, Niyada Naksuk, Lilach Lerman, Samuel J Asirvatham
BACKGROUND: People with heart failure and preserved ejection fraction develop increases in left ventricular (LV) end-diastolic pressures during exercise that contribute to dyspnea. In normal open-chest animal preparations, the pericardium restrains LV filling when central blood volume increases. We hypothesized that resection of the pericardium using a minimally invasive epicardial approach would mitigate the increase in LV end-diastolic pressure that develops during volume loading in normal and diseased hearts with the chest intact...
April 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28377441/percutaneous-transfemoral-tricuspid-valve-edge-to-edge-repair-a-case-series
#17
Karin Müller, Rezo Jorbenadze, Tobias Walker, Robert Schüler, Christoph Hammerstingl, Christian Schlensak, Meinrad Gawaz, Harald F Langer, Peter Seizer
No abstract text is available yet for this article.
April 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28377440/late-migration-of-a-cardiomems-tm-wireless-pulmonary-artery-hemodynamic-monitoring-sensor
#18
Aniket S Rali, Zubair Shah, Andrew Sauer, Kamal Gupta
No abstract text is available yet for this article.
April 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28377439/association-between-use-of-long-acting-nitrates-and-outcomes-in-heart-failure-with-preserved-ejection-fraction
#19
Shir Lynn Lim, Lina Benson, Ulf Dahlström, Carolyn S P Lam, Lars H Lund
BACKGROUND: Nitrates may be beneficial in heart failure with preserved ejection fraction (HFpEF) by enhancing cGMP signaling and improving hemodynamics, but real-world data on potential efficacy are lacking. METHODS AND RESULTS: We linked the Swedish Heart Failure Registry to national registries with International Classification of Diseases, Tenth Revision comorbidity diagnoses and demographic and socioeconomic data. In HFpEF, defined as left ventricular ejection fraction ≥40%, we derived propensity scores for nitrate use using 52 baseline variables...
April 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28364092/use-of-%C3%AE-blockers-in-pulmonary-hypertension
#20
Frédéric Perros, Frances S de Man, Harm J Bogaard, Fabrice Antigny, Gérald Simonneau, Sébastien Bonnet, Steeve Provencher, Nazzareno Galiè, Marc Humbert
Contrasting with the major attention that left heart failure has received, right heart failure remains understudied both at the preclinical and clinical levels. However, right ventricle failure is a major predictor of outcomes in patients with precapillary pulmonary hypertension because of pulmonary arterial hypertension, and in patients with postcapillary pulmonary hypertension because of left heart disease. In pulmonary hypertension, the status of the right ventricle is one of the most important predictors of both morbidity and mortality...
April 2017: Circulation. Heart Failure
journal
journal
42092
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"