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Circulation. Cardiovascular Imaging

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https://www.readbyqxmd.com/read/30214669/tropoelastin-a-novel-marker-for-plaque-progression-and-instability
#1
Alkystis Phinikaridou, Sara Lacerda, Begoña Lavin, Marcelo E Andia, Alberto Smith, Prakash Saha, René M Botnar
Background: Elastolysis and ineffective elastogenesis favor the accumulation of tropoelastin, rather than cross-linked elastin, in atherosclerotic plaques. We developed gadolinium-labeled tropoelastin-specific magnetic resonance contrast agents (Gd-TESMAs) for tropoelastin imaging in animal models. Methods and Results: Two peptides, VVGSPSAQDEASPLS and YPDHVQYTHY were selected to target tropoelastin. In vitro binding, relaxivity, and biodistribution experiments enabled characterization of the probes and selecting the best candidate for in vivo MRI...
August 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/30012831/in-this-issue-of-the-journal
#2
EDITORIAL
Robert J Gropler
No abstract text is available yet for this article.
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/30012830/prognosticating-in-the-very-elderly
#3
EDITORIAL
Randall C Thompson, Krishna K Patel
No abstract text is available yet for this article.
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/30012829/cardiovascular-magnetic-resonance-for-myocardial-inflammation-lake-louise-versus-mapping
#4
EDITORIAL
Matthias G Friedrich
No abstract text is available yet for this article.
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/30012828/prognostic-value-of-serial-echocardiography-in-hypoplastic-left-heart-syndrome-smaller-hearts-better-results
#5
EDITORIAL
Laura Mercer-Rosa, David J Goldberg
No abstract text is available yet for this article.
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/30012827/coronary-atheroma-burden-is-the-main-determinant-of-patient-outcome-but-how-much-detail-is-needed
#6
EDITORIAL
Armin Arbab-Zadeh
No abstract text is available yet for this article.
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/30012826/diagnostic-performance-of-extracellular-volume-native-t1-and-t2-mapping-versus-lake-louise-criteria-by-cardiac-magnetic-resonance-for-detection-of-acute-myocarditis-a-meta-analysis
#7
Jonathan A Pan, Yoo Jin Lee, Michael Salerno
BACKGROUND: The Lake Louise Criteria (LLC) were established in 2009 and are the recommended cardiac magnetic resonance imaging criterion for diagnosing patients with suspected myocarditis. Subsequently, newer parametric imaging techniques which can quantify T1, T2, and the extracellular volume (ECV) have been developed and may provide additional utility in the diagnosis of myocarditis. However, whether their diagnostic accuracy is superior to LLC remains unclear. In this meta-analysis, we compared the diagnostic performance of native T1, T2, ECV to LLC in diagnosing acute myocarditis...
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/30012825/quantification-of-coronary-atherosclerosis-in-the-assessment-of-coronary-artery-disease
#8
Sang-Eun Lee, Ji Min Sung, Asim Rizvi, Fay Y Lin, Amit Kumar, Martin Hadamitzky, Yong-Jin Kim, Edoardo Conte, Daniele Andreini, Gianluca Pontone, Matthew J Budoff, Ilan Gottlieb, Byoung Kwon Lee, Eun Ju Chun, Filippo Cademartiri, Erica Maffei, Hugo Marques, Jonathon A Leipsic, Sanghoon Shin, Jung Hyun Choi, Kavitha Chinnaiyan, Gilbert Raff, Renu Virmani, Habib Samady, Peter H Stone, Daniel S Berman, Jagat Narula, Leslee J Shaw, Jeroen J Bax, James K Min, Hyuk-Jae Chang
BACKGROUND: Diagnosis of coronary artery disease and management strategies have relied solely on the presence of diameter stenosis ≥50%. We assessed whether direct quantification of plaque burden (PB) and plaque characteristics assessed by coronary computed tomography angiography could provide additional value in terms of predicting rapid plaque progression. METHODS AND RESULTS: From a 13-center, 7-country prospective observational registry, 1345 patients (60...
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/30012824/is-there-an-age-when-myocardial-perfusion-imaging-may-no-longer-be-prognostically-useful
#9
Fernanda Erthal, Alomgir Hossain, Sharmila Dorbala, Leslee J Shaw, Marcelo F Di Carli, Michael E Merhige, Brent A Williams, Emir Veledar, James K Min, Daniel S Berman, Robert A deKemp, Rob S B Beanlands, Benjamin J W Chow
BACKGROUND: Heart disease continues to be the leading cause of death, and the prevalence of coronary artery disease is expected to increase as the population ages. It is important to understand the clinical utility of medical tests, or its lack thereof, in the aging population. The objective of this study was to understand the incremental prognostic value of positron emission tomographic (PET) myocardial perfusion imaging in the elderly (≥85 years of age). METHODS AND RESULTS: A total of 3343 patients enrolled in a multicenter observational PET registry were analyzed...
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/30012823/prognostic-value-of-serial-echocardiography-in-hypoplastic-left-heart-syndrome
#10
Jae Sung Son, Adam James, Chun-Po Steve Fan, Luc Mertens, Brian W McCrindle, Cedric Manlhiot, Mark K Friedberg
BACKGROUND: Hypoplastic left heart syndrome (HLHS) carries a high mortality. The prognostic value of echocardiographic variables at presentation and the importance of serial data are poorly explored. METHODS AND RESULTS: We retrospectively analyzed longitudinal clinical and echocardiographic parameters of children with hypoplastic left heart syndrome. The primary outcome was time to death or transplant after stage-1 surgery, right censored at stage 3 surgery, accounting for sequential surgical procedures...
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/30006354/measuring-up-before-birth-the-new-normal
#11
EDITORIAL
Anita J Moon-Grady, Shabnam Peyvandi
No abstract text is available yet for this article.
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/30006353/reference-ranges-for-the-size-of-the-fetal-cardiac-outflow-tracts-from-13-to-36-weeks-gestation-a-single-center-study-of-over-7000-cases
#12
Trisha V Vigneswaran, Ranjit Akolekar, Argyro Syngelaki, Marietta Charakida, Lindsey D Allan, Kypros H Nicolaides, Vita Zidere, John M Simpson
BACKGROUND: Assessment of the outflow tract views is an integral part of routine fetal cardiac scanning. For some congenital heart defects, notably coarctation of the aorta, pulmonary valve stenosis, and aortic valve stenosis, the size of vessels is important both for diagnosis and prognosis. Existing reference ranges of fetal outflow tracts are derived from a small number of cases. METHODS AND RESULTS: The study population comprised 7945 fetuses at 13 to 36 weeks' gestation with no detectable abnormalities from pregnancies resulting in normal live births...
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29970382/stress-in-the-single-ventricle-old-concepts-new-tools
#13
EDITORIAL
Willem A Helbing
No abstract text is available yet for this article.
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29970381/high-risk-plaque-regression-and-stabilization-hybrid-noninvasive-morphological-and-hemodynamic-assessment
#14
Andreas A Giannopoulos, Dimitrios Mitsouras, Andrea Bartykowszki, Béla Merkely, Yiannis S Chatzizisis, Ronny R Buechel, Philipp A Kaufmann, Oliver Gaemperli, Pál Maurovich-Horvat
No abstract text is available yet for this article.
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29970380/caseous-calcification-of-the-mitral-annulus-with-atrial-and-ventricular-fistulization
#15
Sumit Gupta, Yin Ge, Maaz A Ghouri, Ron Blankstein, Michael L Steigner, Ayaz Aghayev
No abstract text is available yet for this article.
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29970379/impact-of-ventricular-morphology-on-fiber-stress-and-strain-in-fontan-patients
#16
Sunil J Ghelani, Steven D Colan, Nina Azcue, Ellen M Keenan, David M Harrild, Andrew J Powell, Tal Geva, Rahul H Rathod
BACKGROUND: Right ventricular (RV) morphology has been associated with adverse clinical outcomes in Fontan patients. The impact of RV versus left ventricular morphology on ventricular stress and strain in single ventricles is not well known. METHODS AND RESULTS: Cardiac magnetic resonance examinations in 193 patients with the Fontan circulation were retrospectively analyzed. Ventricular mass, volume, global circumferential and longitudinal strain, and global average end-systolic fiber stress were calculated using previously published methods...
July 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29914870/myocardial-hypertrophy-matrix-expansion-and-focal-scar-progression-and-regression-in-aortic-stenosis
#17
EDITORIAL
Thomas A Treibel, Paul Richard Scully, James C Moon
No abstract text is available yet for this article.
June 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29914869/comparison-of-computational-fluid-dynamics-and-machine-learning-based-fractional-flow-reserve-in-coronary-artery-disease
#18
EDITORIAL
Ashish Yeri, Ravi V Shah
No abstract text is available yet for this article.
June 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29914868/chess-and-coronary-artery-ischemia-clinical-implications-of-machine-learning-applications
#19
EDITORIAL
James K Min
No abstract text is available yet for this article.
June 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29914867/progression-of-hypertrophy-and-myocardial-fibrosis-in-aortic-stenosis-a-multicenter-cardiac-magnetic-resonance-study
#20
Russell J Everett, Lionel Tastet, Marie-Annick Clavel, Calvin W L Chin, Romain Capoulade, Vassilios S Vassiliou, Jacek Kwiecinski, Miquel Gomez, Edwin J R van Beek, Audrey C White, Sanjay K Prasad, Eric Larose, Christopher Tuck, Scott Semple, David E Newby, Philippe Pibarot, Marc R Dweck
BACKGROUND: Aortic stenosis is accompanied by progressive left ventricular hypertrophy and fibrosis. We investigated the natural history of these processes in asymptomatic patients and their potential reversal post-aortic valve replacement (AVR). METHODS: Asymptomatic and symptomatic patients with aortic stenosis underwent repeat echocardiography and magnetic resonance imaging. Changes in peak aortic-jet velocity, left ventricular mass index, diffuse fibrosis (indexed extracellular volume), and replacement fibrosis (late gadolinium enhancement [LGE]) were quantified...
June 2018: Circulation. Cardiovascular Imaging
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