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Journal of Gastrointestinal Cancer

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https://www.readbyqxmd.com/read/28211016/adenocarcinoma-ex-goblet-cell-carcinoid-of-the-appendix-a-case-report-and-overview-of-the-disease
#1
Uroosa Ibrahim, Gautam Valecha, Gwenalyn Garcia, Amina Saqib, Monika Wrzolek, Meekoo Dhar
No abstract text is available yet for this article.
February 17, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28197777/autoimmune-pancreatitis-masquerading-as-pancreatic-cancer-when-in-doubt-cut-it-out
#2
Henry Y Jiang, Erica L Kohtakangas, Bojana Mitrovic, Kengo Asai, Jeffrey B Shum
No abstract text is available yet for this article.
February 15, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28194556/pancreatoblastoma-an-atypical-presentation-and-a-literature-review
#3
Marisa Terino, Eileen Plotkin, Raffi Karagozian
No abstract text is available yet for this article.
February 14, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28168400/double-trouble-synchronous-adenocarcinoma-of-gallbladder-and-pancreas
#4
Pavankumar Vijayaraj, Sandip Chandrasekar, Raja Kalayarasan, Biju Pottakkat
No abstract text is available yet for this article.
February 7, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28154967/comparison-of-clinical-outcomes-between-laparoscopic-assisted-and-minilaparotomy-approaches-for-colon-cancer
#5
Zuoliang Liu, Tong Zhou, Guodong Yang, Guangjun Zhang
BACKGROUND/AIMS: The minilaparotomy approach is feasible for the resection of colon cancer. This study aimed to compare the clinical and oncological outcomes of minilaparotomy and laparoscopic approaches in patients with colon cancer. METHODS: We performed a retrospective analysis of consecutive patients undergoing minilaparotomy or laparoscopic resection for colon cancer from January 2009 to December 2014. RESULTS: There were 376 patients with colon cancer...
February 3, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28124769/prevalence-of-her2-positivity-and-its-clinicopathological-correlation-in-locally-advanced-metastatic-gastric-cancer-patients-in-malaysia
#6
Pathmanathan Rajadurai, Ho Kean Fatt, Foo Yoke Ching
PURPOSE: Human epidermal growth factor receptor 2 (Erbb2/HER2) overexpression, which was previously detected in invasive breast cancer, has now been implicated in advanced gastric cancer (GC) and gastroesophageal junction cancer (GEC). A study was conducted to determine the rate of HER2 positivity in patients with locally advanced or metastatic GC and GEC in Malaysia and to assess the impact of various demographic and clinical parameters on HER2 positivity. METHODS: A total of 228 adult patients with GC or GEC were enrolled from Subang Jaya Medical Centre, Malaysia, for retrospective (210) and prospective study...
January 26, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28124240/epigenetic-downregulation-of-pten-in-gallbladder-cancer
#7
Dinesh Singh Tekcham, Sanjeev Gupta, Braj Raj Shrivastav, Pramod Kumar Tiwari
PURPOSE: Gallbladder cancer (GBC) is becoming a global health problem. Phosphatase and tensin homolog (PTEN), also known as guardian gene of cancer, encodes a protein, which dephosphorylates phosphatidylinositol (3,4,5) triphosphate {PtdIns (3,4,5) P3 } into phosphatidylinositol (4,5) diphosphate {PtdIns (4,5) P2} that results in the inhibition of AKT/PKB signaling pathway. PTEN plays a key role in the pathogenesis of various cancers. However, its role in GBC is still obscure. The present study was aimed to identify the epigenetic role of PTEN in GBC and GSD...
January 26, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28105553/does-ca-19-9-have-prognostic-relevance-in-gallbladder-carcinoma-gbc
#8
Sushma Agrawal, Able Lawrence, Rajan Saxena
BACKGROUND: There is a scarce data on prognostic relevance of carbohydrate antigen (CA 19-9). This retrospective study was undertaken to evaluate its prognostic relevance in different prognostic subsets of gallbladder carcinoma (GBC). MATERIALS AND METHODS: One hundred forty-one patients of GBC treated between January 2012 and December 2014 were the subjects of this retrospective analysis. Baseline CA 19-9 levels of four cohorts of patients: extended cholecystectomy (EC), simple cholecystectomy (SC) with residual or recurrent disease, locally advanced disease (LAGBC) and metastatic disease were ascertained...
January 20, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28093684/portocaval-paraganglioma-first-case-report-and-review-of-literature
#9
Kaushal Yadav, Satyam Taneja, Rajiv Dang, Shreeja Menon, Gaurav Kapoor, Ashish Patil, Akash Banwari
No abstract text is available yet for this article.
January 17, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28093683/simple-clinical-score-to-predict-24-week-survival-times-in-patients-with-inoperable-malignant-distal-biliary-obstruction-as-a-tool-for-selecting-palliative-metallic-or-plastic-stents
#10
Pimsiri Sripongpun, Siriboon Attasaranya, Naichaya Chamroonkul, Theerapong Sookpaisal, Uthai Khow-Ean, Aroon Siripun, Chanon Kongkamol, Teerha Piratvisuth, Bancha Ovartlarnporn
BACKGROUND AND AIM: Endoscopic biliary drainage (EBD) is the mainstay treatment for inoperable malignant distal biliary obstruction (MDBO). Some authorities suggest that metallic stents are more cost-effective than plastic stents in patients with expected survival of at least 6 months. However, studies attempting to define the predictive factors for such survival times are limited. This study aims to develop a scoring system for predicting a survival time of <24 weeks in these patients...
January 17, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28092014/a-rare-entity-of-gastrointestinal-stromal-tumour-arising-from-a-meckel-s-diverticulum-a-case-report
#11
Kshitij Manerikar, Iqbal Ali, Chandradip Patil, Mirat Dholakia, Pratham Mody
No abstract text is available yet for this article.
January 14, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28066869/a-case-report-stevens-johnson-syndrome-as-an-adverse-effect-of-capecitabine
#12
Priyanka Jadhav, Jane E Rogers, Rachna Shroff
No abstract text is available yet for this article.
January 9, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28066868/gastric-metastasis-from-hepatocellular-carcinoma-a-rare-manifestation
#13
Mohamed Seenikatty Abdul Hakim, Ahmad Najib Azmi, Pailoor Jayalakshmi, Sanjiv Mahadeva
No abstract text is available yet for this article.
January 9, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28058527/outcomes-of-a-phase-i-ii-trial-of-hepatic-arterial-infusion-of-oxaliplatin-combined-with-intravenous-5-fluorouracil-and-l-leucovorin-in-patients-with-unresectable-liver-metastases-from-colorectal-cancer-after-systemic-chemotherapy-failure
#14
Yozo Sato, Yoshitaka Inaba, Takashi Ura, Hideyuki Nishiofuku, Hidekazu Yamaura, Mina Kato, Daisuke Takahari, Toshihiro Tanaka, Kei Muro
PURPOSE: The purpose of this study was to assess hepatic arterial infusion (HAI) of oxaliplatin combined with intravenous 5-fluorouracil (5-FU) and l-leucovorin (l-LV) in colorectal cancer (CRC) patients with systemic chemotherapy failure in a phase I/II trial. METHODS: CRC patients with unresectable liver metastases following standard systemic chemotherapy failure were eligible. A catheter-port system for HAI was placed using interventional radiology. In phase I, escalating doses of oxaliplatin for levels 1 and 2 were set at 50 and 100 mg/m(2), respectively, and were combined with fixed doses of intravenous 5-FU (200 mg/m(2) bolus and 2400 mg/m(2)/46-h continuous infusion) and l-LV (200 mg/m(2))...
January 6, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28044264/clinicopathological-associations-of-k-ras-and-n-ras-mutations-in-indonesian-colorectal-cancer-cohort
#15
Michael Levi, Gintang Prayogi, Farid Sastranagara, Edi Sudianto, Grace Widjajahakim, Winiarti Gani, Albert Mahanadi, Jocelyn Agnes, Bela Haifa Khairunisa, Ahmad R Utomo
BACKGROUND: K-RAS and recently N-RAS gene mutation testing are mandatory requirements prior to anti-epidermal growth factor receptor (EGFR) monoclonal antibody treatment of metastatic CRC. Mutation prevalence and distribution in Indonesian colorectal cancer (CRC) are not known. METHODS: Combined methods of PCR high-resolution melt (HRM), restriction fragment length polymorphism (RFLP), and direct DNA sequencing were used to genotype exons 2, 3, and 4 of both K-RAS and N-RAS genes for routine clinical testing of CRC patients...
January 3, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28044263/five-fraction-stereotactic-body-radiation-therapy-sbrt-and-chemotherapy-for-the-local-management-of-metastatic-pancreatic-cancer
#16
Jonathan W Lischalk, Aidan Burke, Jessica Chew, Christen Elledge, Marie Gurka, John Marshall, Michael Pishvaian, Sean Collins, Keith Unger
BACKGROUND: The majority of patients with pancreatic cancer are diagnosed with metastatic disease at presentation. Nevertheless, local progression is responsible for up to 30% of deaths and can lead to significant morbidity. As a consequence, further exploration of effective methods of local control and palliation is essential. Stereotactic body radiation therapy (SBRT) is a widely utilized technique for the treatment of localized pancreatic cancer. Here, we report our experience with SBRT and chemotherapy for the local treatment of the metastatic patient population...
January 3, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28044262/brain-metastasis-as-initial-presentation-of-rectal-adenocarcinoma-an-unusual-case-in-a-very-young-patient
#17
Jyotsana Sinha, Rong Zhang, Vinit V Patil, Miguel A Guzman, Nishant Poddar
No abstract text is available yet for this article.
January 3, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28032292/leiomyosarcoma-involving-the-pancreas-diagnosed-by-endoscopic-ultrasound-fine-needle-aspiration
#18
Mohamed Abdelfatah, Eric M Gochanour
No abstract text is available yet for this article.
December 29, 2016: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28028766/health-related-quality-of-life-in-patients-with-metastatic-pancreatic-cancer
#19
Vincent Picozzi, Siva Narayanan, X Henry Hu, Jeffrey Vacirca
PURPOSE: Due to its clinical course and often-late detection, many patients with metastatic pancreatic cancer (mPC) experience poor quality of life (QoL). This pilot project assessed real-world QoL in patients with mPC at different stages of treatment. METHODS: A cross-sectional survey was conducted in the following groups of patients with mPC: before initiation of first-line (1L) chemotherapy (no treatment); with partial response (PR) or stable disease (SD) upon receipt of ≥3 cycles of 1L nab-paclitaxel plus gemcitabine (nab-paclitaxel plus gemcitabine PR or SD); and with disease progression during ≥1L chemotherapy and not currently receiving nab-paclitaxel (≥1L PD)...
December 28, 2016: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28028765/an-alternative-method-for-screening-gastric-cancer-based-on-serum-levels-of-cea-ca19-9-and-ca72-4
#20
Junxiu Yu, Wanlei Zheng
PURPOSE: The goal of this study was to create a novel method for screening gastric cancer (GC) based on serum levels of carcinoembryonic antigen (CEA), cancer antigen 19-9 (CA19-9), and cancer antigen 72-4 (CA72-4) tumor markers. METHODS: Retrospectively, the predictive value for GC was calculated using a logistic analysis on serum levels of CEA, CA19-9, and CA72-4 from 216 GC and 49 benign patients. The predictive value was used to make a recommendation system on whether further GC screening was necessary...
December 28, 2016: Journal of Gastrointestinal Cancer
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