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Journal of Gastrointestinal Cancer

Muneer J Al-Husseini, Anas M Saad, Tarek Turk, Mohamed A Tabash, Omar Abdel-Rahman
PURPOSE: Pancreatic cancer is one of the most fatal malignancies and the fourth leading cause of cancer-related mortality in the USA. Most clinical trials involving pancreatic adenocarcinoma (PAC) patients exclude subjects with a prior malignancy because of the possible effect of prior malignancies on survival. However, no data in the medical literature support this assumption. In this paper, we aim to study the impact of having a prior malignancy on the survival outcomes of stage IV PAC...
August 14, 2018: Journal of Gastrointestinal Cancer
Matthew Michael Sochat, Jinhua Piao, Nishant Poddar
No abstract text is available yet for this article.
August 13, 2018: Journal of Gastrointestinal Cancer
Kutay Saglam, Fatih Sumer, Cihan Gokler, Ayse Nur Akatli, Cuneyt Kayaalp
No abstract text is available yet for this article.
August 9, 2018: Journal of Gastrointestinal Cancer
Nikolaos S Salemis, Ilias Katikaridis, Andreas Zografidis
No abstract text is available yet for this article.
August 6, 2018: Journal of Gastrointestinal Cancer
Fernando Meton de Alencar Camara Vieira, Ana Paula Ornellas de Souza Victorino, Daniel de Iracema Gomes Cubero, Carlos Augusto de Mendonça Beato, Eimy Minowa, Guilherme Silva Julian, Diego Novick
PURPOSE: In Brazil, patients with gastric cancer have not been systematically followed-up and evaluated, thus data regarding patterns of care and outcomes are scarce or missing. The objective of this study was to evaluate patterns of care of advanced gastric cancer in standard practice in Brazil. METHODS: This was an observational, multicenter, retrospective study, which included patients with metastatic and/or unresectable gastric cancer (MGC) who underwent at least one line of treatment...
August 4, 2018: Journal of Gastrointestinal Cancer
Patricia Segales-Rojas, Leonardo S Lino-Silva, Eduardo Aguilar-Cruz, Rosa A Salcedo-Hernández
PURPOSE: Gastrointestinal stromal tumors (GIST) have the potential to recur and metastasize. Several prognostic schemes have been developed but none are precise enough and most times the pathologist faces a small biopsy where it is not possible to evaluate the mitotic count. Our aim was to determine the influence of ki67 index and other clinicopathologic characteristics in the recurrence of GIST. METHODS: Forty-three consecutive cases of GIST were studied. The cases presented with non-metastatic disease...
July 31, 2018: Journal of Gastrointestinal Cancer
Marissa B Savoie, Alan Paciorek, Li Zhang, Erin L Van Blarigan, Nilli Sommovilla, Donald Abrams, Chloe E Atreya, Emily K Bergsland, Hueylan Chern, Robin K Kelley, Andrew Ko, Angela Laffan, Ankit Sarin, Madhulika G Varma, Alan P Venook, Katherine Van Loon
PURPOSE: We aimed to described 25-hydroxyvitamin D [25(OH)D] levels in newly diagnosed colorectal cancer (CRC) patients and to re-evaluate levels after chemotherapy. METHODS: Permanent residents of the San Francisco Bay Area with a new CRC diagnosis of any stage were recruited prior to any non-surgical therapy. Serum 25(OH)D levels were measured at time of diagnosis and 6-month follow-up. Supplement use was not restricted. The primary endpoint was the frequency of vitamin D deficiency in patients with newly diagnosed CRC of all stages...
July 30, 2018: Journal of Gastrointestinal Cancer
Monika Magdy, Tarek Hussein, Ahmed Ezzat, Ahmed Gaballah
BACKGROUND: Gastric cancer is the fifth cancer worldwide. Inflammatory response increases metastasis through apoptosis inhibition and angiogenesis augmentation. The neutrophil-lymphocyte ratio (NLR), which is a balance between pro-cancer inflammatory and anti-cancer immune responses, was proved as prognostic marker. Peripheral NLR is a good reflection of tumor microenvironment. METHODS: We retrospectively collected data of gastric and gastro-esophageal cancer patients treated from January 2015 till December 2016...
July 30, 2018: Journal of Gastrointestinal Cancer
Tawfik Khoury, Muhammad Massarwa, Wadi Hazou, Saleh Daher, David Hakimian, Ariel A Benson, Toni Ashqar, Mahmud Mahamid, Shaul Yaari
PURPOSE: Portal vein thrombosis (PVT) is a common condition in cirrhotic patients and mostly attributed to portal hypertension. The objective of our study was to examine the association of PVT with hepatocellular carcinoma (HCC) in cirrhotic patients. METHODS: A retrospective study was performed to identify cirrhotic patients with thrombosis of the portal system. Clinical and laboratory characteristics were collected and analyzed. RESULTS: Thirty-nine patients were identified...
July 25, 2018: Journal of Gastrointestinal Cancer
Ryan Anthony F Agas, Lester Bryan A Co, J C Kennetth M Jacinto, Kelvin Ken L Yu, Paolo G Sogono, Warren R Bacorro, Teresa T Sy Ortin
PURPOSE: The aim of this study is to review the contemporary evidence comparing neoadjuvant radiotherapy (NRT) versus no radiotherapy (no RT) in patients with stage IV rectal cancer. METHODS: Literature was searched for studies using the following databases: Pubmed, EMBASE, Science Direct, Scopus, ASCOpubs, the Cochrane Library, and Google Scholar. Studies reporting outcomes for stage IV rectal cancer patients who underwent NRT or no RT were selected. RESULTS: A total of eight studies were included in this review (one RCT, five retrospective cohorts, two population-based studies)...
July 25, 2018: Journal of Gastrointestinal Cancer
Cacey Peters, Eleanor Lewin, Tong Wu, Yukihiro Nakanishi
No abstract text is available yet for this article.
July 25, 2018: Journal of Gastrointestinal Cancer
Apostolos Gaitanidis, Michail Alevizakos, Alexandra Tsaroucha, Michail Pitiakoudis
PURPOSE: Primary tumor location has been identified as an important prognostic factor among patients with gastrointestinal stromal tumors (GISTs). The purpose of this study is to identify how primary tumor location may affect outcomes after resection for patients with metastatic GISTs. METHODS: Patients with GISTs and distant metastases at diagnosis were identified in the Surveillance Epidemiology and End Results (SEER) database. Patients that underwent surgery were matched to patients that did not undergo surgery using propensity score matching (PSM) analysis...
July 23, 2018: Journal of Gastrointestinal Cancer
Ján Csomor, Bohuš Bunganič, Dominika Dvořáková, Petr Hříbek, Klára Kmochová, Vít Campr, Inna Tučková, Cyril Šálek, Petr Urbánek, Miroslav Zavoral
No abstract text is available yet for this article.
July 23, 2018: Journal of Gastrointestinal Cancer
Mehdi Heidari Horestani, Golnaz Atri Roozbahani, Masoud Sheidai
PURPOSE: Tumor necrosis factor-α has been suggested to play a crucial role in the development andprogression of hepatocellular carcinoma (HCC). Previous reports have indicated that rs361525 and rs1800629 might be risk factors for various cancers. Increasing studies have been conducted on the association of these two SNPs with HCC risk but the results remain inconclusive. METHODS: In order to detect association between TNF- α and HCC, a meta-analysis was performed...
July 20, 2018: Journal of Gastrointestinal Cancer
Saba Karimi, Alireza Abdi, Alireza Khatony, Mohamad Akbari, Azam Faraji
INTRODUCTION AND OBJECTIVE: Colorectal cancer is the fourth prevalent cancer in the world and there are several factors effective on development of the disease. These factors vary based on geographical distribution. The present study is aimed at surveying epidemiology of colorectal cancer and its risk factors in Kermanshah-Iran between 2009 and 2014. METHODOLOGY: A descriptive cross-sectional study was carried out on all colorectal cancer cases in two Kermanshah-based hospitals Imam Reza and Taleghani between 2009 and 2014...
July 19, 2018: Journal of Gastrointestinal Cancer
Hamza Arif, Kristen Suchniak-Mussari, Kyle Cothron, Rachel Toney
No abstract text is available yet for this article.
July 16, 2018: Journal of Gastrointestinal Cancer
Abdullah Alsuhaibani, Ahmed Elashwah, Rana Mahmood, Alaa Abduljabbar, Samar Alhomoud, Luai Ashari, Shouki Bazarbashi, Ali Aljubran, Ahmed Alzahrani, Muhamed Mohiuddin, Hadeel Almanea, Hussah Alhussaini, Nasser AlSanea
PURPOSE: Assess feasibility-rate of PCR, short-term toxicity after neoadjuvant concurrent chemoradiation (NACRT) delivered via simultaneous integrated boost (SIB) using volumetric modulated arc therapy (VMAT) technique for locally advanced rectal cancer. METHODS: Retrospective evaluation of patients with locally advanced rectal cancer treated with VMAT-SIB technique preoperatively at an academic tertiary care center in Riyadh, Saudi Arabia between February 2013 and March 2017...
July 14, 2018: Journal of Gastrointestinal Cancer
A Ramos-Esquivel, E Cordero-García, D Brenes-Redondo, W Alpízar-Alpízar
INTRODUCTION: High values of neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are related with poor prognosis in patients with gastric cancer. However, this association has been rarely assessed in Hispanic populations that show important clinicopathological differences to Asian and Caucasian patients. In this study, we determined the prognostic value of these biomarkers in Hispanic patients from Costa Rica. MATERIALS AND METHODS: We retrieved data regarding pre-treatment NLR and PLR, as well as clinical variables from medical records of 381 consecutive gastric cancer patients treated in four major hospitals in Costa Rica between 2009 and 2012...
July 13, 2018: Journal of Gastrointestinal Cancer
Akwasi Ofori Abayie, K M Nyarko, N Loza, G Pistorius, J Thies
No abstract text is available yet for this article.
July 13, 2018: Journal of Gastrointestinal Cancer
Yakup Bozkaya, U Aydın, A Avcı, D Tuncer, E Yılmaz
No abstract text is available yet for this article.
July 13, 2018: Journal of Gastrointestinal Cancer
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