Read by QxMD icon Read

Journal of Gastrointestinal Cancer

Abdullah Alsuhaibani, Ahmed Elashwah, Abdullah Alkafi, Camelia Constantinescus, Faisal ALzorkany
OBJECTIVES: We retrospectively evaluate local control rate at 6 months and 1 year in oligometastatic cancer patients treated with SBRT using CyberKnife. METHODS: Total of 21 patients with 24 treatment sites from February 2014 till June 2017 who were treated with SBRT in our institution were included in this study. RESULTS: Eleven patients were males, 10 patients were females, median age at diagnosis was 63 years, and colorectal cancer is the most commonly diagnosed cancer in 18 patients...
October 6, 2018: Journal of Gastrointestinal Cancer
Barbara Kościelniak-Merak, Branimir Radosavljević, Andrzej Zając, Przemysław J Tomasik
BACKGROUND: Early detection of colorectal cancer decreases the risk of mortality. Faecal occult blood tests (FOBT) are recognised as a useful tool for colorectal cancer screening. These non-invasive, rapid, and easy-to-carry assays are very often used as a point-of-care test and for self-testing. On the market, there are various types of FOB tests available, including chemical and immunochromatographic tests, which are based on different detection methods and differ in their sensitivity and specificity...
September 20, 2018: Journal of Gastrointestinal Cancer
Rachel N Saunders, Emiko Hayakawa, Charles J Gibson, Alistair J Chapman
No abstract text is available yet for this article.
September 10, 2018: Journal of Gastrointestinal Cancer
Saurabh Singhal, Harit Kapoor, Saravanan Subramanian, Devendra K Agrawal, Sumeet K Mittal
PURPOSE: The vitamin D receptor (VDR) endocrine system has emerged as an endogenous pleiotropic biological cell regulator with anti-neoplastic effects on breast, colorectal, and prostatic adenocarcinomas. We studied the association of gene expression, polymorphisms of VDR, CYP27B1, and CYP24A1 genes and serum vitamin D levels as surrogate markers of disease progression in patients with acid reflux, Barrett's esophagus (BE), or esophageal adenocarcinoma (EAC). METHODS: We analyzed blood and tissue samples from patients with biopsy-confirmed BE or EAC for vitamin D levels, gene expressions, and polymorphisms in VDR (FokI [F/f], BsmI [B/b], ApaI [A/a], and TaqI [T/t]), CYP27B1 (HinfI [H/h]), and CYP24A1 (Hpy1881 [Y/y])...
September 5, 2018: Journal of Gastrointestinal Cancer
Vaibhav Kumar Varshney, Jyotsna Naresh Bharti, Binit Sureka, Subhash Chandra Soni
No abstract text is available yet for this article.
September 4, 2018: Journal of Gastrointestinal Cancer
Sankalp Singh, Niharika Bisht, Richa Joshi, Prabha Shankar Mishra, Deepak Mulajker, Samir Gupta
No abstract text is available yet for this article.
September 3, 2018: Journal of Gastrointestinal Cancer
Daniel M Girardi, Luiza Dib B B Faria, Marcela C Teixeira, Frederico P Costa, Paulo Marcelo G Hoff, Gustavo S Fernandes
PURPOSE: Advanced pancreatic adenocarcinoma (PA) is an aggressive disease that has poor prognosis and frequently interferes with patient's quality of life. There has been progress in first-line regimens; however, there is no standard second-line regimen. The aim of this study is to analyze second-line gemcitabine after first-line fluorouracil (FU) + leucovorin (LV) + irinotecan + oxaliplatin (FOLFIRINOX) regimen. METHODS: This study included consecutive patients with advanced PA treated at Hospital Sirio-Libanês from 2011 to 2016...
September 3, 2018: Journal of Gastrointestinal Cancer
Milad Asadi, Dariush Shanehbandi, Venus Zafari, Vahid Khaze, Mohammad Hosein Somi, Shahriar Hashemzadeh
BACKGROUND: Aberrant expression of microRNAs (miRNAs) has been implicated in the etiopathogenesis and development of various cancers. Drosha and Dicer are the main components of the miRNA biosynthesis machine. Another enzyme, DGCR8, is the assistant of Drosha in the processing complex. Here, we tried to evaluate the mRNA transcript level of Drosha, Dicer, and DGCR8 genes in involved tissues from patients with gastric cancer. METHODS: Fifty tumoral and their marginal tissues, as the control group, were obtained from patients with gastric cancer...
August 31, 2018: Journal of Gastrointestinal Cancer
Sutapa Halder, Sayan Kundu, Jayati Chakraborty, Sudipta Chakrabarti
BACKGROUND: HER2 is an oncoprotein which is overexpressed in several cancers including breast and stomach. Several studies have shown that HER2 is overexpressed in gallbladder cancer and in precancerous lesions. The present study was undertaken to assess pattern and level of expression of HER2 in metaplasia, dysplasia, and different stages of gallbladder carcinoma, which would determine its suitability as a prognostic biomarker in neoplastic transformation of gallbladder epithelium. The study was also aimed at to find the significance of Ki-67 index in these lesions...
August 29, 2018: Journal of Gastrointestinal Cancer
Anil Kumar Singh Rana, Nitin Agarwal, Sushant Dutta, Manoj Kumar Dokania, Himank Goyal
No abstract text is available yet for this article.
August 24, 2018: Journal of Gastrointestinal Cancer
Salem Y Mohamed, Randa Mohamed Kaf, Mona Mostafa Ahmed, Amira Elwan, Hassan R Ashour, Amr Ibrahim
BACKGROUND: Cancer stem cells proved to have a vital role in cell migration, invasion, metastasis, and treatment resistance of colorectal cancer (CRC) that subsequently lead to poor clinical outcomes. These stem cells may be a novel therapeutic target for the management of CRC progression. Signals of the Notch-1 pathway are responsible for acquisition of stem cell characters. ALDH1 and CD44 are usually detected in stem cells in colorectal cancer. AIM: The aims of this work are to evaluate the immunohistochemical expression of cancer stem cell markers ALDH1, Notch1, and CD44 in colorectal cancer and investigate their correlation with clinicopathological characters and patient survival...
August 23, 2018: Journal of Gastrointestinal Cancer
Sohyla Reshadat, Shahram Saeidi, Alireza Zangeneh, Arash Ziapour, Fariba Saeidi, Maryam Choobtashani
INTRODUCTION: The trend of cancers has witnessed a twofold rise in the last three decades, which is expected to be fivefold by 2030. On the other hand, gastrointestinal cancers have turned into one of the health issues in many societies. Given the presence of gastrointestinal cancer hot spots and evidence of health inequalities across Kermanshah Metropolis and the results of studies signaling the association between gastrointestinal cancers and socioeconomic status of individuals as well as evidence of unequal socioeconomic opportunities in this metropolis, the present study aimed to investigate the spatial distribution of gastrointestinal cancers in the poverty and affluent strata of Kermanshah Metropolis, Iran...
August 23, 2018: Journal of Gastrointestinal Cancer
Maxine D Fisher, Sonia Pulgar, Matthew H Kulke, Beloo Mirakhur, Paul J Miller, Mark S Walker, Lee S Schwartzberg
PURPOSE: Metastatic neuroendocrine tumors (mNETs) are rare, heterogeneous tumors that present diagnostic and treatment challenges, with limited data on the management of mNETs in clinical practice. The present study was designed to identify current diagnostic and treatment patterns in mNET patients treated in the US community oncology setting. METHODS: Patient-level data was collected from medical records of adults with mNETs from the Vector Oncology Data Warehouse, a comprehensive US community oncology network database...
August 18, 2018: Journal of Gastrointestinal Cancer
Yanshuo Cao, Qing Chang, Michael Cabanero, Wenjiang Zhang, Sara Hafezi-Bakhtiari, David Hedley, Gail Darling, Fayez Quereshy, Raymond Jang, Elena Elimova, Jennifer Knox, Olga Ornatsky, Stefano Serra, Eric Chen
PURPOSE: There is a wide range in tumor response following preoperative chemotherapy in locally advanced gastric or gastroesophageal junction cancers. We investigated the relationship between tumor platinum levels and pathological responses in these patients. METHODS: Tumor and adjacent normal tissues were retrieved. Pathological responses were assessed per standard criteria. Tissue platinum concentrations were determined with high-performance liquid chromatography mass spectrometry...
August 16, 2018: Journal of Gastrointestinal Cancer
Richard H Lewis, Evan S Glazer, David M Bittenbinder, Thomas O'Brien, Jeremiah L Deneve, David Shibata, Stephen W Behrman, Jason M Vanatta, Sanjaya K Satapathy, Paxton V Dickson
BACKGROUND: Hepatocellular carcinoma (HCC) occasionally occurs in non-cirrhotic patients; however, outcomes for these patients are not extensively documented. METHODS: We performed an institutional review of patients without cirrhosis who underwent resection for HCC. Clinical data were evaluated to identify factors impacting recurrence-free survival (RFS) and overall survival (OS). RESULTS: Forty-two patients underwent hepatectomy for HCC in the absence of cirrhosis over a 10-year period...
August 16, 2018: Journal of Gastrointestinal Cancer
Muneer J Al-Husseini, Anas M Saad, Tarek Turk, Mohamed A Tabash, Omar Abdel-Rahman
PURPOSE: Pancreatic cancer is one of the most fatal malignancies and the fourth leading cause of cancer-related mortality in the USA. Most clinical trials involving pancreatic adenocarcinoma (PAC) patients exclude subjects with a prior malignancy because of the possible effect of prior malignancies on survival. However, no data in the medical literature support this assumption. In this paper, we aim to study the impact of having a prior malignancy on the survival outcomes of stage IV PAC...
August 14, 2018: Journal of Gastrointestinal Cancer
Matthew Michael Sochat, Jinhua Piao, Nishant Poddar
No abstract text is available yet for this article.
August 13, 2018: Journal of Gastrointestinal Cancer
Kutay Saglam, Fatih Sumer, Cihan Gokler, Ayse Nur Akatli, Cuneyt Kayaalp
No abstract text is available yet for this article.
August 9, 2018: Journal of Gastrointestinal Cancer
Nikolaos S Salemis, Ilias Katikaridis, Andreas Zografidis
No abstract text is available yet for this article.
August 6, 2018: Journal of Gastrointestinal Cancer
Fernando Meton de Alencar Camara Vieira, Ana Paula Ornellas de Souza Victorino, Daniel de Iracema Gomes Cubero, Carlos Augusto de Mendonça Beato, Eimy Minowa, Guilherme Silva Julian, Diego Novick
PURPOSE: In Brazil, patients with gastric cancer have not been systematically followed-up and evaluated, thus data regarding patterns of care and outcomes are scarce or missing. The objective of this study was to evaluate patterns of care of advanced gastric cancer in standard practice in Brazil. METHODS: This was an observational, multicenter, retrospective study, which included patients with metastatic and/or unresectable gastric cancer (MGC) who underwent at least one line of treatment...
August 4, 2018: Journal of Gastrointestinal Cancer
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"