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Journal of Otolaryngology—Head & Neck Surgery

M Roskies, E Kay-Rivest, M A Mascarella, K Sultanem, A Mlynarek, M Hier
BACKGROUND: A commonly employed treatment for advanced staged oropharyngeal squamous cell carcinoma (OPSCC) is concurrent radiation and chemotherapy with cisplatin as the gold standard. Carboplatin is reported to have the same radiopotentiation properties and a superior side effect profile; however, its use in head and neck cancer has been limited due to the paucity of data and reported hematologic side effects. In this study, we describe our institution's experience with carboplatin, paclitaxel and radiation in the treatment of oropharyngeal squamous cell carcinoma over a 10 year period...
October 10, 2016: Journal of Otolaryngology—Head & Neck Surgery
Tina Hu, Katherine Stead, Terence Fu, Blake Papsin
BACKGROUND: Hearing deficits in children are demonstrably negatively associated with language acquisition and cognition. Although universal neonatal hearing screening exists, it is not offered equally across Canada. Additionally, children emigrating from other countries are often not assessed. The objective of this study is to evaluate Kids2Hear, a free hearing screening program run by medical students at elementary schools, and to determine the rate of hearing deficits that were identified and referred for evaluation...
September 26, 2016: Journal of Otolaryngology—Head & Neck Surgery
Cigdem Fırat Koca, Tamer Erdem, Tuba Bayındır
BACKGROUND: Deformity in the dental arc and facial skeleton by adenoid hypertrophy due to chronic mouth breathing is a well-known process. Most of the related studies have been based on cephalometric analyses. The aim of this study is to detect the presence of skeletal deformities on the soft tissue by analyzing distances and angles on photographs. METHODS: Ninety-seven children having between 25 and 100 % of adenoids, ages 4-12 years (48 boys, 49 girls), and 90 cases having 0-25 % adenoid tissue, ages 4-12 years (54 boys, 36 girls), were studied by clinical history, physical examination (including endoscopy), and standardized clinical photographs...
September 20, 2016: Journal of Otolaryngology—Head & Neck Surgery
Daniel L Faden, Sarah T Arron, Chase M Heaton, Joseph DeRisi, Andrew P South, Steven J Wang
BACKGROUND: Little is known regarding the etiology and genomic underpinnings of Oral Tongue Squamous Cell Carcinoma (OTSCC) in patients who lack traditional risk factors, yet the incidence is increasing. In particular, the rate, and role, of TP53 mutations in this cohort has been heavily debated in the literature. METHODS: Tumor DNA from forty-three non-smokers with OTSCC underwent next generation sequencing of TP53. RESULTS: Sixty percent of samples contained a TP53 mutation...
2016: Journal of Otolaryngology—Head & Neck Surgery
Anne Conlin, Jane Lea, Manohar Bance, Neil Chadha, Shaun Kilty, Frederick Kozak, Julian Savage, Ravindar Sidhu, Joseph Chen, Brian D Westerberg
BACKGROUND: Mental practice, the cognitive rehearsal of a task in the absence of overt physical movement, has been successfully used in teaching complex psychomotor tasks including sports and music, and recently, surgical skills. The objectives of this study were, 1) To develop and evaluate a mental practice protocol for mastoidectomy 2) To assess the immediate impact of mental practice on a mastoidectomy surgical task among senior Otolaryngology─Head & Neck Surgery (OHNS) residents...
2016: Journal of Otolaryngology—Head & Neck Surgery
Soroush Larjani, Eric Monteiro, Ian Witterick, Allan Vescan, Gelareh Zadeh, Fred Gentili, David P Goldstein, John R de Almeida
BACKGROUND: The Skull Base Inventory (SBI) was developed to assess the quality of life of patients undergoing endoscopic or open approaches for anterior and central skull base pathologies. In this study, we sought to establish the discriminative and evaluative properties for this instrument. METHODS: The SBI was administered in a cross-sectional fashion to patients who previously had skull base surgery after treatment and then again 2 weeks after completing the instrument...
2016: Journal of Otolaryngology—Head & Neck Surgery
James Belyea, Brandon Wickens, Manohar Bance
BACKGROUND: Gas pressure balance is essential for maintaining normal middle ear function. The mucosal surfaces of the middle ear, the mastoid air cell system (MACS), and the Eustachian tube (ET) play a critical role in this process; however, the extent that each of these factors contributes to overall middle ear ventilation is unknown. The objective of this study was to determine if the ET alone can maintain normal middle ear pressure without the MACS. To do this, we reviewed subjects who had their MACS completely removed with translabyrinthine (TL) surgery for vestibular schwannoma...
2016: Journal of Otolaryngology—Head & Neck Surgery
Brian W Rotenberg, Dorian Murariu, Kenny P Pang
BACKGROUND: Obstructive sleep apnea (OSA) is a common disorder, and continuous airway positive pressure (CPAP) is considered to be the gold standard of therapy. CPAP however is known to have problems with adherence, with many patients eventually abandoning the device. The purpose of this paper is to assess secular trends in CPAP adherence over the long term to see if there have been meaningful improvements in adherence in light of the multiple interventions proposed to do so. METHODS: A comprehensive systematic literature review was conducted using the Medline-Ovid, Embase, and Pubmed databases, searching for data regarding CPAP adherence over a twenty year timeframe (1994-2015)...
2016: Journal of Otolaryngology—Head & Neck Surgery
R J De Santis, I Poon, J Lee, I Karam, D J Enepekides, K M Higgins
BACKGROUND: The literature reports various treatment methodologies, such as trans-oral laser microsurgery, radiation therapy, total/partial laryngectomies, and concurrent radiation chemotherapy for patients with early larynx cancer. However, at the forefront of early glottis treatment is trans-oral laser microsurgery and radiation therapy, likely due to better functional and survival outcomes. Here we conduct the largest Canadian head-to-head comparison of consecutive patients treated with either radiation therapy or trans-oral laser microsurgery...
2016: Journal of Otolaryngology—Head & Neck Surgery
Oleksandr Butskiy, Donald W Anderson, Eitan Prisman
BACKGROUND: Gastric pull up remains a popular reconstructive option for pharyngoesophagectomy defects extending to thoracic inlet. Gastric necrosis is a dreaded complication of gastric pull up reconstruction and few studies report on management of this complication. MEDLINE, EMBASE, and Web of Science™ databases were searched for publications in the last 25 years on gastric pull up reconstruction following pharyngoesophagectomy. The rates of complications related to gastropharyngeal anastomosis were extracted, and methods of managing gastric necrosis were noted...
2016: Journal of Otolaryngology—Head & Neck Surgery
A Foreman, R J De Santis, F Sultanov, D J Enepekides, K M Higgins
BACKGROUND: Total laryngectomy (TL) is an appropriate oncologic operation for many patients with laryngeal cancer delivering excellent oncologic outcomes, however it remains beset with significant functional consequences. Following TL, the upper and lower airways are permanently disconnected, which causes unfiltered, cold air with reduced humidity to enter the tracheobronchial tree, resulting in mucus overproduction and an increase in the viscosity of the mucus. In response to this, Heat and moisture exchangers were developed to compensate for the lost functions of the upper respiratory tract and their effect on the patients' respiratory performance in addition to their quality of life...
2016: Journal of Otolaryngology—Head & Neck Surgery
Liang Chen, Hui Xu, Wu-Qing Wang, Qing-Quan Zhang, Qiao-Ying Lv, Xi-Cheng Song
BACKGROUND: Cervical and ocular vestibular evoked myogenic potentials (c/oVEMPs) reflect otolith function. Up-to-date, there are no published reports on the systemic evaluation of otolith function in Ménière's Disease (MD) nor are there any reports on the differences in VEMPs between patients with early and late stage MD. The aim of this study was to evaluate the difference in c/oVEMPs between patients with MD and normal controls, as well as between patients with early and late stage MD...
2016: Journal of Otolaryngology—Head & Neck Surgery
Gavin J le Nobel, Euna Hwang, Adrian Wu, Sharon Cushing, Vincent Y Lin
BACKGROUND: Many Canadians are affected by sensorineural hearing loss (SNHL) and those with severe or profound hearing loss may have poor hearing function despite optimized hearing aids. Cochlear implants (CI) offer effective hearing rehabilitation for these patients, however, concern continues to exist regarding possible effects of CI on the vestibular system and balance. The objective of this study was to conduct a pilot study assessing the effects of unilateral cochlear implantation (CI) on balance and the vestibular system in post-lingually deafened adults...
2016: Journal of Otolaryngology—Head & Neck Surgery
Yaw Amoako-Tuffour, Philip Garland, Manohar Bance
BACKGROUND: Sonotubometry is a non-invasive means of assessing Eustachian tube (ET) function. Its interpretation remains a complex task with questionable results due to wide variation between trials. A study was conducted to ascertain whether the measurement of phase shift in sonotubometric signals would be a more reliable indicator of ET patency than fluctuating Sound Pressure Level (SPL). METHODS: The ears of six healthy participants and two participants with patulous ET (PET) were probed with a 100 Hz signal...
2016: Journal of Otolaryngology—Head & Neck Surgery
Gordon Fung-Zak Tsang, Carmen L McKnight, Laura Minhui Kim, John M Lee
BACKGROUND: Patients with chronic rhinosinusitis (CRS) often have to endure significant wait times for endoscopic sinus surgery (ESS). The pyschiatric impact of placement on a waitlist for ESS has not been explored. METHODS: Questionnaires measuring CRS symptom severity and health-related anxiety and stress (SNOT-22, HADS, WPAI-GH) were sent to patients diagnosed with CRS and currently on a waitlist for ESS. Fifteen representative waitlisted patients participated in one-on-one semi-structured interviews discussing their experience with their wait for ESS...
2016: Journal of Otolaryngology—Head & Neck Surgery
Sabin Filimon, Keith Richardson, Michael P Hier, Michael Roskies, Alex M Mlynarek
BACKGROUND: Lip reconstruction for defects greater than 80 % present a challenge in maintaining acceptable oral function and good aesthetic results. Abbé flaps offer an excellent reconstructive option but are limited to defects under 65 %. METHODS: We describe a two-stage "modified Abbé island flap" technique whereby a full-thickness myocutaneous flap is combined with a modified Karapandzic flap, allowing for reconstruction of total and near total lip defects...
2016: Journal of Otolaryngology—Head & Neck Surgery
A Butler, M H Rigby, J Scott, J Trites, R Hart, S M Taylor
BACKGROUND: The purpose of this study was to evaluate the functional and oncological outcomes of patients treated for T3 laryngeal squamous cell carcinoma. Specifically comparing transoral laser microsurgery and radiotherapy/chemoradiotherapy treatment modalities. METHOD: A retrospective review of patients treated for T3 laryngeal SCC between 2002 and 2010 was undertaken. RESULTS: Forty-nine patients were included. 15 cases were glottic, (9 treated with TLM, 6 with RT/CRT), 33 supraglottic (6 treated with TLM, 27 with RT/CRT) and 1 subglottic subsite (treated with RT/CRT)...
2016: Journal of Otolaryngology—Head & Neck Surgery
Rodrigo Salazar-Gamarra, Rosemary Seelaus, Jorge Vicente Lopes da Silva, Airton Moreira da Silva, Luciano Lauria Dib
PURPOSE: The aim of this study is to present the development of a new technique to obtain 3D models using photogrammetry by a mobile device and free software, as a method for making digital facial impressions of patients with maxillofacial defects for the final purpose of 3D printing of facial prostheses. METHODS: With the use of a mobile device, free software and a photo capture protocol, 2D captures of the anatomy of a patient with a facial defect were transformed into a 3D model...
2016: Journal of Otolaryngology—Head & Neck Surgery
Khalid Hussain Al-Qahtani, Mutahir A Tunio, Yasser Bayoumi, Venkada Manickam Gurusamy, Fahad Ahmed A Bahamdain, Hanadi Fatani
BACKGROUND: Salivary ductal carcinoma (SDC) of parotid gland is a rare and aggressive entity; accounting for 1-3 % of all malignant salivary gland tumors, 0.2 % of epithelial salivary gland neoplasms, 0.5 % of salivary gland carcinomas, and 1.1 % of parotid gland carcinomas. Here in we aimed to evaluate the clinico-pathological features and treatment outcomes of parotid gland SDC in Saudi population. METHODS: Among 38 patients with parotid malignancies, who were treated in two major tertiary care referral cancer centers between December 2007 and December 2014, seven cases (18...
2016: Journal of Otolaryngology—Head & Neck Surgery
S Hosseini, R J Payne, F Zawawi, A Mlynarek, M P Hier, M Tamilia, V I Forest
BACKGROUND: It has been reported that thyroglobulin antibody are more frequently elevated in patients with thyroid cancercompared to general population. This study aims at evaluating whether preoperative thyroglobulin antibody (TgAb) levels increase the likelihood that a thyroid nodule is malignant. METHODS: A retrospective review of 586 patients who underwent thyroidectomy was conducted. Demographic data, TgAb levels, and final histopathology were recorded. Patients were divided into two groups: TgAb positive (defined as TgAb ≥ 30 IU/ml) and TgAb low/negative (defined as TgAb < 30)...
2016: Journal of Otolaryngology—Head & Neck Surgery
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