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Journal of Otolaryngology—Head & Neck Surgery

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https://www.readbyqxmd.com/read/29454371/auditory-effects-of-autologous-fat-graft-for-torp-stabilization-in-the-middle-ear-a-cadaveric-study
#1
Margaret Aron, Thomas G Landry, Manohar Bance
BACKGROUND: Total ossicular replacement prostheses (TORP) are often used to re-establish ossicular coupling of sound in an ear lacking a stapes supra-structure. The use of TORPs, however, is associated with a 2/3 five year failure rate due to their anatomic instability over time in the middle ear. The use of autologous fat to try and stabilize TORPs may improve long-term results with this challenging ossicular reconstruction technique. METHODS: A cadaveric temporal bone model was developed and laser Doppler vibrometry was used to measure and record round window membrane vibration in response to sound stimulation under the following conditions: normal middle ear, middle ear filled with fat, normal middle ear with TORP prosthesis, TORP prosthesis with fat around its distal end and TORP prosthesis with fat filling the middle ear...
February 17, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29444706/bilateral-piriform-sinus-fistulas-a-case-study-and-review-of-management-options
#2
Deanna Lammers, Ross Campbell, Jorge Davila, Johnna MacCormick
BACKGROUND: Piriform sinus fistulas occur due to developmental abnormalities of the third and fourth branchial arches, and almost always occur unilaterally. They generally present as recurrent abscesses in the anterior-inferior neck, with concurrent thyroiditis. They have conventionally been managed with complete removal of the sinus tract, and thyroidectomy if required; however, endoscopic approaches have been increasingly favored. Herein we describe a case of bilateral piriform sinus fistulas, and present a review of the literature concerning their endoscopic management...
February 14, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29444694/reliability-and-construct-validity-of-the-ottawa-valve-collapse-scale-when-assessing-external-nasal-valve-collapse
#3
Hedyeh Ziai, James P Bonaparte
BACKGROUND: Nasal valve collapse is a common cause of nasal obstruction in otolaryngology practice. Common examination methods, such as the Cottle Maneuver and modified Cottle Maneuver are available. However, these methods are dichotomous and do not provide ordinal severity information. The Ottawa Valve Collapse Scale (OVCS) is a grading system for assessing and easily grading external nasal valve collapse in patients with a septal deviation. The primary objective was to assess the test-retest reliability and construct validity of the OVCS grading scale...
February 14, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29433567/laryngeal-recurrence-sites-in-patients-previously-treated-with-transoral-laser-microsurgery-for-squamous-cell-carcinoma
#4
P Horwich, M H Rigby, C MacKay, J Melong, B Williams, M Bullock, R Hart, J Trites, S M Taylor
BACKGROUND: The laryngeal framework provides a natural barrier preventing tumour spread to extralaryngeal structures. Transoral laser microsurgery (TLM) for laryngeal squamous cell carcinoma (SCC) may violate these boundaries, altering the pathways of tumor spread for potential recurrences. Our project objective is to describe laryngeal SCC recurrence patterns and overall survival in patients requiring total laryngectomy (TL) after TLM. METHODS: Patients undergoing TLM for laryngeal SCC requiring salvage TL were identified from a prospective CO2 laser database containing all patients undergoing TLM for head and neck malignancies at the QEII Health Sciences Center in Halifax, Nova Scotia between March 2002 - May 2014...
February 13, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29433566/differences-in-gene-expression-profile-between-vocal-cord-leukoplakia-and-normal-larynx-mucosa-by-gene-chip
#5
Jianhua Peng, He Li, Jun Chen, Xianming Wu, Tao Jiang, Xiaoyun Chen
BACKGROUND: Long non-coding RNAs (lncRNAs) play an important role in tumorigenesis. Vocal cord leukoplakia is a precancerous lesion in otolaryngological practice. Till now, the expression patterns and functions of lncRNAs in vocal cord leukoplakia have not been well understood. In this study, we used microarrays to investigate the aberrantly expressed lncRNAs and mRNAs in vocal cord leukoplakia and adjacent non-neoplastic tissues. METHODS: Gene Ontology and pathway analyses were performed to determine the significant function and pathways of the differentially expressed mRNAs...
February 12, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29402322/cochlear-implants-and-1-5%C3%A2-t-mri-scans-the-effect-of-diametrically-bipolar-magnets-and-screw-fixation-on-pain
#6
Ingo Todt, Grit Rademacher, Gloria Grupe, Andreas Stratmann, Arne Ernst, Sven Mutze, Philipp Mittmann
BACKGROUND: The probability that a patient will need an MRI scan at least once in a lifetime is high. However, MRI scanning in cochlear implantees is associated with side effects. Moreover, MRI scan-related artifacts, dislodging magnets, and pain are often the most frequent complications. The aim of this study was to evaluate the occurrence of pain in patients with cochlear implant systems using 1.5T MRI scans. METHODS: In a prospective case study of 10 implantees, an MRI scan was performed and the degree of pain was evaluated by a visual analog scale...
February 5, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29402308/cavernous-sinus-involvement-is-not-a-risk-factor-for-the-primary-tumor-site-treatment-outcome-of-sinonasal-adenoid-cystic-carcinoma
#7
Yi-Chan Lee, Ta-Jen Lee, Ngan-Ming Tsang, Yenlin Huang, Cheng-Lung Hsu, Li-Jen Hsin, Yi-Hsuan Lee, Kai-Ping Chang
BACKGROUND: Sinonasal adenoid cystic carcinoma is a rare malignancy of the head and neck. Cavernous sinus invasion from sinonasal adenoid cystic carcinoma and its related management have rarely been investigated. This study evaluated the relationship between treatment outcome and cavernous sinus involvement in addition to other parameters. METHODS: A retrospective case series study was conducted at a tertiary referral center. The medical records of 47 patients diagnosed with primary sinonasal adenoid cystic carcinoma between 1984 and 2015 were retrospectively reviewed...
February 5, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29394952/renal-protective-effect-of-a-hydration-supplemented-with-magnesium-in-patients-receiving-cisplatin-for-head-and-neck-cancer
#8
Takahiro Kimura, Taijiro Ozawa, Nobuhiro Hanai, Hitoshi Hirakawa, Hidenori Suzuki, Hiroshi Hosoi, Yasuhisa Hasegawa
BACKGROUND: Our study analyzes the effect of magnesium supplementation on nephrotoxicity in patients receiving cisplatin for head and neck cancer. METHODS: We retrospectively reviewed the medical records of patients with head and neck cancer who received two doses of cisplatin (80 mg/m2) and 5-fluorouracil (800 mg/m2) 3 weeks apart from August 2008 to October 2012. The regimen prior to 2011 (crystalloid-only) involved the administration of 1000 mL of lactated Ringer's solution on the day prior to cisplatin infusion and 2000 mL of continuous infusion of saline on the day of cisplatin infusion...
February 2, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29382382/resolution-of-unilateral-sensorineural-hearing-loss-in-a-pediatric-patient-with-a-severe-phenotype-of-muckle-wells-syndrome-treated-with-anakinra-a-case-report-and-review-of-the-literature
#9
Cinzia Marchica, Faisal Zawawi, Dania Basodan, Rosie Scuccimarri, Sam J Daniel
BACKGROUND: Muckle-Wells syndrome (MWS) is a rare auto-inflammatory disease characterized by the presence of recurrent urticaria, deafness and amyloidosis. Progressive sensorineural hearing loss (SNHL) is reported to occur in up to 85% of patients occurring in the second and third decades and as early as the first decade in patients with a more severe phenotype, thus potentially having a significant impact on a child's development. IL-1 inhibitors, such as Anakinra, have been described to improve systemic inflammation, and stabilize or improve hearing status as well...
January 30, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29378664/the-prevalence-of-human-papillomavirus-in-pediatric-tonsils-a-systematic-review-of-the-literature
#10
REVIEW
Monika Wojtera, Josee Paradis, Murad Husein, Anthony C Nichols, John W Barrett, Marina I Salvadori, Julie E Strychowsky
BACKGROUND: HPV-related head and neck cancer rates have been increasing in recent years, with the tonsils being the most commonly affected site. However, the current rate of HPV infection in the pediatric population remains poorly defined. The objective of this study was to systematically review and evaluate the prevalence and distribution of HPV in the tonsils of pediatric patients undergoing routine tonsillectomy. METHODS AND RESULTS: The literature was searched using PubMed, EMBASE, Scopus, CINAHL, Cochrane Library, and ProQuest Dissertations & Theses Global databases (inception to December 2017) by two independent review authors...
January 30, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29361981/intraoperative-brief-electrical-stimulation-of-the-spinal-accessory-nerve-best-spin-for-prevention-of-shoulder-dysfunction-after-oncologic-neck-dissection-a-double-blinded-randomized-controlled-trial
#11
Brittany Barber, Hadi Seikaly, K Ming Chan, Rhys Beaudry, Shannon Rychlik, Jaret Olson, Matthew Curran, Peter Dziegielewski, Vincent Biron, Jeffrey Harris, Margaret McNeely, Daniel O'Connell
BACKGROUND: Shoulder dysfunction is common after neck dissection for head and neck cancer (HNC). Brief electrical stimulation (BES) is a novel technique that has been shown to enhance neuronal regeneration after nerve injury by modulating the brain-derived neurotrophic growth factor (BDNF) pathways. The objective of this study was to evaluate the effect of BES on postoperative shoulder function following oncologic neck dissection. METHODS: Adult participants with a new diagnosis of HNC undergoing Level IIb +/- V neck dissection were recruited...
January 23, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29357932/does-hyperthyroidism-worsen-prognosis-of-thyroid-carcinoma-a-retrospective-analysis-on-2820-consecutive-thyroidectomies
#12
REVIEW
Fabio Medas, Ernico Erdas, Gian Luigi Canu, Alessandro Longheu, Giuseppe Pisano, Massimiliano Tuveri, Pietro Giorgio Calò
BACKGROUND: Hyperthyroidism is associated with high incidence of thyroid carcinoma; furthermore, tumors arisen in hyperthyroid tissue show an aggressive behavior. Thyroid Stimulating Hormone (TSH) and Thyroid-stimulating antibodies, present in Graves's disease, seem to play a key role in carcinogenesis and tumoral growth. METHODS: We retrospectively reviewed our series of patients who underwent thyroidectomy for thyroid carcinoma. We compared pathological features and surgical outcomes of hyperthyroid versus euthyroid patients...
January 22, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29357924/an-automated-a-value-measurement-tool-for-accurate-cochlear-duct-length-estimation
#13
John E Iyaniwura, Mai Elfarnawany, Hanif M Ladak, Sumit K Agrawal
BACKGROUND: There has been renewed interest in the cochlear duct length (CDL) for preoperative cochlear implant electrode selection and postoperative generation of patient-specific frequency maps. The CDL can be estimated by measuring the A-value, which is defined as the length between the round window and the furthest point on the basal turn. Unfortunately, there is significant intra- and inter-observer variability when these measurements are made clinically. The objective of this study was to develop an automated A-value measurement algorithm to improve accuracy and eliminate observer variability...
January 22, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29316976/clinical-implications-of-the-braf-mutation-in-papillary-thyroid-carcinoma-and-chronic-lymphocytic-thyroiditis
#14
Woon Won Kim, Tae Kwun Ha, Sung Kwon Bae
BACKGROUND: The purpose of this study was to examine the possible prognostics and clinicopathologic characteristics underlying the BRAFV600E mutation and papillary thyroid carcinoma (PTC) coexisting or in absence of chronic lymphocytic thyroiditis (CLT). METHODS: This study was conducted on 172 patients who had undergone total thyroidectomy or unilateral total thyroidectomy for PTC; the patients were then examined for the BRAFV600E mutation using specimens obtained after their surgery from January 2013 to August 2015...
January 9, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29310719/head-and-neck-surgical-oncology-choosing-wisely-campaign-imaging-for-patients-with-hoarseness-fine-needle-aspiration-for-neck-mass-and-ultrasound-for-odynophagia
#15
LETTER
Antoine Eskander, Eric Monteiro, Dan O'Connell, S Mark Taylor
Choosing Wisely Canada, is a campaign designed to raise awareness regarding inappropriate or unnecessary tests and treatments. The Canadian Society of Otolaryngology - Head & Neck Surgery and the Canadian Association of Head and Neck Surgical Oncologists developed a Choosing Wisely Canada list to help promote high quality care for patients presenting with disorders of the head and neck: (1) Don't order imaging - computer tomography (CT) or magnetic resonance imaging (MRI) - as the initial investigation for patients presenting with a chief complaint of hoarseness, (2) Don't perform an open biopsy or excision of a neck mass without having first considered a fine needle aspiration (FNA) biopsy and, (3) Don't order neck ultrasound to investigate odynophagia (discomfort or pain with swallowing) or globus sensation...
January 8, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29310703/management-of-persistent-epistaxis-using-floseal-hemostatic-matrix-vs-traditional-nasal-packing-a-prospective-randomized-control-trial
#16
Scott Murray, Adrian Mendez, Alexander Hopkins, Hamdy El-Hakim, Caroline C Jeffery, David W J Côté
BACKGROUND: Epistaxis is the most common emergent consultation to otolaryngology-head & neck surgery (OHNS) and with 60% of the population having experienced an episode and 1.6 in 10,000 requiring hospitalization in their lifetime. In preliminary studies Floseal® (Baxter, USA) Hemostatic Matrix has shown efficacy in up to 80% of persistent anterior epistaxis. We sought to evaluate the clinical efficacy and cost-effectiveness of Floseal® (Baxter, USA) compared to traditional nasal packing for persistent epistaxis...
January 8, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29301560/delayed-facial-nerve-decompression-for-severe-refractory-cases-of-bell-s-palsy-a-25-year-experience
#17
Ilyes Berania, Mohamed Awad, Issam Saliba, Jean-Jacques Dufour, Marc-Elie Nader
BACKGROUND: This study aims to assess the effectiveness of delayed facial nerve decompression for Bell's palsy (BP). METHODS: We performed a retrospective case review of all patients having undergone facial nerve decompression for severe refractory BP between 1984 and 2009 at our tertiary referral center. Demographics, timing between onset of symptoms and surgical decompression, degree of facial nerve dysfunction pre- and post-operatively, follow-up length after surgery and postoperative complications were recorded...
January 4, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29282128/improving-learning-and-confidence-through-small-group-structured-otoscopy-teaching-a-prospective-interventional-study
#18
Peng You, Saad Chahine, Murad Husein
BACKGROUND: Otologic diseases are common and associated with significant health care costs. While accurate diagnosis relies on physical exam, existing studies have highlighted a lack of comfort among trainees with regards to otoscopy. As such, dedicated otoscopy teaching time was incorporated into the undergraduate medical curriculum in the form of a small group teaching session. In this study, we aimed to examine the effect of a small-group, structured teaching session on medical students' confidence with and learning of otoscopic examination...
December 28, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29262865/surgical-management-of-inverted-papilloma-a-single-center-analysis-of-247-patients-with-long-follow-up
#19
Oisín Bugter, Dominiek André Monserez, Floris Vincent Willem Joseph van Zijl, Robert Jan Baatenburg de Jong, Jose Angelito Hardillo
BACKGROUND: Our aim was to review our management of inverted papilloma (IP), perform a recurrence analysis, and review the literature. METHODS: A retrospective analysis of 247 patients treated for an IP. Patients were grouped according to surgical approach, tumor presentation (primary, residual and recurrence) and Krouse-stage. RESULTS: Recurrence was observed in 20.3%, 28.6% and 35.1% (p = 0.017) of the patients who underwent endoscopic, external and combined surgery, respectively...
December 20, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29228990/mannitol-and-the-blood-labyrinth-barrier
#20
Trung N Le, Brian W Blakley
BACKGROUND: Characterization of the blood labyrinth barrier (BLB) is extremely important to determine whether the BLB can be manipulated pharmacologically. However, experiments to investigate the BLB are technically difficult to perform. In this report, we demonstrated a unique method of controlling the BLB, and established the pharmacokinetics of gentamicin in perilymph, cerebrospinal fluid (CSF) and blood with and without mannitol. STUDY DESIGN: Controlled animal research project...
December 11, 2017: Journal of Otolaryngology—Head & Neck Surgery
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