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Journal of Otolaryngology—Head & Neck Surgery

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https://www.readbyqxmd.com/read/28490377/cochlear-implant-electrode-sealing-techniques-and-related-intracochlear-pressure-changes
#1
Ingo Todt, Julica Utca, Dania Karimi, Arne Ernst, Philipp Mittmann
BACKGROUND: The inserted cochlear implanted electrode is covered at the site of the round window or cochleostomy to prevent infections and leakage. In a surgically hearing preservational concept, low intracochlear pressure changes are of high importance. The aim of this study was to observe intracochlear pressure changes due to different sealing techniques in a cochlear model. METHODS: Cochlear implant electrode insertions were performed in an artifical cochlear model and the intracochlear pressure changes were recorded in parallel with a micro-pressure sensor positioned in the apical region of the cochlea model to follow the maximum amplitude of intracochlear pressure...
May 11, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28482917/management-delays-in-patients-with-squamous-cell-cancer-of-neck-node-s-and-unknown-primary-site-a-retrospective-cohort-study
#2
Kevin Martell, Joanna Mackenzie, Warren Kerney, Harold Yeehau Lau
BACKGROUND: We aim to characterize the workup received by and identify any delays to diagnosis or treatment in patients referred to a tertiary cancer centre with the diagnosis of squamous cell carcinoma in neck node(s) and no identifiable primary (SCCNIP). METHODS: Over 1 year, 68 patients were initially referred to the Head and Neck clinic with a label of "primary unknown". After extensive workup, 29 of the 68 patients were found to have pathologically confirmed SCCNIP...
May 8, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28482866/development-and-validation-of-an-administrative-data-algorithm-to-identify-adults-who-have-endoscopic-sinus-surgery-for-chronic-rhinosinusitis
#3
Kristian I Macdonald, Shaun J Kilty, Carl van Walraven
BACKGROUND: This was a diagnostic accuracy study to develop an algorithm based on administrative database codes that identifies patients with Chronic Rhinosinusitis (CRS) who have endoscopic sinus surgery (ESS). METHODS: From January 1(st), 2011 to December 31(st), 2012, a chart review was performed for all hospital-identified ESS surgical encounters. The reference standard was developed as follows: cases were assigned to encounters in which ESS was performed for Otolaryngologist-diagnosed CRS; all other chart review encounters, and all other hospital surgical encounters during the timeframe were controls...
May 8, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28476166/predictors-of-failure-of-dise-directed-adenotonsillectomy-in-children-with-sleep-disordered-breathing
#4
Noura Alsufyani, Andre Isaac, Manisha Witmans, Paul Major, Hamdy El-Hakim
BACKGROUND: Adenotonsillectomy (AT) is the most commonly performed procedure for sleep disordered breathing (SDB) in pediatrics. However, 20-40% of patients will have persistent signs and symptoms of SDB after AT. Drug-induced sleep endoscopy (DISE) has the potential to individualize surgical treatments and avoid unnecessary or unsuccessful surgeries. The objective of this study was to determine the predictors of failure of DISE-directed adenoidectomy and/or tonsillectomy in otherwise healthy children with SDB...
May 5, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28464955/il-5-and-il-6-are-increased-in-the-frontal-recess-of-eosinophilic-chronic-rhinosinusitis-patients
#5
Kazunori Kubota, Sachio Takeno, Takayuki Taruya, Atsushi Sasaki, Takashi Ishino, Katsuhiro Hirakawa
BACKGROUND: Eosinophilic chronic frontal sinusitis is difficult to treat compared with non-eosinophilic sinusitis because of recurring inflammation and polyp formation in the frontal recess after the post-operative follow-up period. Studying inflammatory mediators in the frontal recess of eosinophilic chronic rhinosinusitis (ECRS) patients and non-eosinophilic chronic rhinosinusitis (non-ECRS) patients may lead to a better understanding of the pathogenesis of chronic frontal sinusitis...
May 2, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28449725/maxillofacial-prosthodontics-practice-profile-a-survey-of-non-united-states-prosthodontists
#6
Nina Ariani, Harry Reintsema, Kathleen Ward, Cortino Sukotjo, Alvin G Wee
BACKGROUND: This study surveyed non-United States maxillofacial prosthodontists (MFP) to determine their practice profile and rationale for pursuing an MFP career. METHODS: Email addresses for the MFP were obtained from the International Society for Maxillofacial Rehabilitation, American Academy of Maxillofacial Prosthetics, and International Academy for Oral Facial Rehabilitation. Emails with a link to the electronic survey program were sent to each participant...
April 27, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28449724/does-medical-school-research-productivity-predict-a-resident-s-research-productivity-during-residency
#7
Scott Kohlert, Laura Zuccaro, Laurie McLean, Kristian Macdonald
BACKGROUND: Research productivity is an important component of the CanMEDS Scholar role and is an accreditation requirement of Canadian Otolaryngology training programs. Our objective was to determine if an association exists between publication rates before and during Otolaryngology residency. METHODS: We obtained the names for all certified Canadian Otolaryngologists who graduated between 1998 and 2013 inclusive, and conducted a Medline search for all of their publications...
April 27, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28420435/comparison-of-the-mechanical-properties-of-different-skin-sites-for-auricular-and-nasal-reconstruction
#8
M F Griffin, B C Leung, Y Premakumar, M Szarko, P E Butler
BACKGROUND: Autologous and synthetic nasal and auricular frameworks require skin coverage. The surgeon's decides on the appropriate skin coverage for reconstruction based on colour matching, subcutaneous tissue thickness, expertise and experience. One of the major complications of placing subcutaneous implants is the risk of extrusion (migration through the skin) and infection. However, knowledge of lessening the differential between the soft tissue and the framework can have important implications for extrusion...
April 18, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28412967/factors-associated-with-lingual-tonsil-hypertrophy-in-canadian-adults
#9
Matthew S Harris, Brian W Rotenberg, Kathryn Roth, Leigh J Sowerby
BACKGROUND: Hypertrophy of the lingual tonsil tissue in the adult patient is thought to contribute to the pathophysiology of obstructive sleep apnea. The underlying etiology of lingual tonsil hypertrophy (LTH) in the adult patient is unclear and likely multifactorial. Previous studies have suggested that the lingual tonsils may undergo compensatory hyperplasia post-tonsillectomy in children, although it is unknown if this occurs or persists into adulthood. The purpose of this study was to determine what factors are associated with LTH in a population of Canadian adults...
April 17, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28399908/using-cone-beam-ct-to-assess-the-upper-airway-after-surgery-in-children-with-sleep-disordered-breathing-symptoms-and-maxillary-mandibular-disproportions-a-clinical-pilot
#10
Noura A Alsufyani, Michelle L Noga, Manisha Witmans, Irene Cheng, Hamdy El-Hakim, Paul W Major
BACKGROUND: The surgical excision of anatomic obstructions such as adenoids, palatine or lingual tonsils are commonly performed in children with sleep disordered breathing (SDB). Imaging studies measuring airway changes post-surgery in the SDB pediatric population are scarce, rarely addresses the nasal cavity, and are based on global measures (e.g. volume) that do not represent the complexity of the upper airway anatomy. The purpose of this pilot is to test the feasibility in using cone beam CT (CBCT) to analyze the nasal and pharyngeal airway space post-surgery using meaningful methods of analyses, and correlating imaging findings with clinical outcomes in children with SDB symptoms and maxillary-mandibular disproportion...
April 11, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28390434/surgical-site-infections-following-oral-cavity-cancer-resection-and-reconstruction-is-a-risk-factor-for-plate-exposure
#11
Christopher M Yao, Hedyeh Ziai, Gordon Tsang, Andrea Copeland, Dale Brown, Jonathan C Irish, Ralph W Gilbert, David P Goldstein, Patrick J Gullane, John R de Almeida
BACKGROUND: Plate-related complications following head and neck cancer ablation and reconstruction remains a challenging problem often requiring further management and reconstructive surgeries. We aim to identify an association between surgical site infections (SSI) and plate exposure. METHODS: A retrospective study between 1997 and 2014 was performed to study the association between postoperative SSI and plate exposures. Eligible patients included those with a history of oral squamous cell carcinoma who underwent surgical resection, neck dissection, and free tissue reconstruction...
April 8, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28376930/predictors-of-hearing-recovery-in-patients-with-severe-sudden-sensorineural-hearing-loss
#12
Daniel Weiss, Armin Julius Böcker, Mario Koopmann, Eleftherios Savvas, Matthias Borowski, Claudia Rudack
BACKGROUND: Sudden sensorineural hearing loss (SSHL) is a disease, which severely affects the patient's social and relational life. The underlying pathomechanisms have not been finally clarified yet and outcome is not predictable. METHODS: We conducted a retrospective study in order to identify parameters that influence hearing recovery. The data base contains results of basic otoneurological tests and clinical parameters of 198 patients with idiopathic SSHL of at least 60 dB in at least four frequencies, diagnosed and treated at the University Hospital of Münster, Germany, between 1999 and 2015...
April 4, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28376913/the-t4-t3-quotient-as-a-risk-factor-for-differentiated-thyroid-cancer-a-case-control-study
#13
Mark Sasson, Emily Kay-Rivest, Rami Shoukrun, Anca Florea, Michael Hier, Veronique-Isabelle Forest, Michael Tamilia, Richard J Payne
BACKGROUND: The incidence of thyroid nodules is increasing among patients in North America. Few of these nodules harbour malignancy, thus further research is required to identify predictive markers of malignant thyroid disease. This study set out to understand the relationship between the levels of fT4 and fT3 and differentiated thyroid cancer. METHODS: A case-control study was conducted with 142 cases and 86 controls from the McGill University Teaching Hospitals...
April 4, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28376866/systemic-therapy-in-the-curative-treatment-of-head-and-neck-squamous-cell-cancer-a-systematic-review
#14
REVIEW
Eric Winquist, Chika Agbassi, Brandon M Meyers, John Yoo, Kelvin K W Chan
OBJECTIVE: To review the available evidence and make recommendations regarding use of systemically administered drugs in combination or in sequence with radiation (RT) and/or surgery for cure and/or organ preservation in patients with locally advanced nonmetastatic (Stage III to IVB) squamous cell carcinoma of the head and neck (LASCCHN). METHOD: Recognizing the Meta-analysis of Chemotherapy in Head and Neck Cancer (MACH-NC) group reports have de facto guided practice since 2000, we searched for systematic reviews in the MEDLINE, EMBASE and Cochrane Database of Systematic Reviews published from January 2000 to February 2015 in reference to 4 research questions...
April 4, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28376853/a-large-giant-cell-tumor-of-the-larynx-case-report-and-review-of-the-literature
#15
Andrew Arndt, Rachelle LeBlanc, Peter Spafford
BACKGROUND: Giant cell tumors (GCTs) are typically found in the metaphyseal-epiphyseal area of long bones but can also occur in the head and neck region. GCT of the larynx is a rare entity with only 42 reported cases in the international literature. Furthermore, to the best of our knowledge this is the largest laryngeal GCT reported in the literature to date. GCT of the larynx can present with dysphonia, dyspnea, and/or dysphagia and should be considered in the differential diagnosis of a neck mass...
April 4, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28372589/the-first-canadian-experience-with-the-afirma%C3%A2-gene-expression-classifier-test
#16
Emily Kay-Rivest, Jamie Tibbo, Sarah Bouhabel, Michael Tamilia, Rebecca Leboeuf, Veronique-Isabelle Forest, Michael P Hier, Loren Savoury, Richard J Payne
BACKGROUND: Thyroid nodules are common and often benign, although prove to be malignant upon surgical pathology in 5-15% of cases. When assessed with ultrasound-guided fine-needle aspiration (USFNA), 15-30% of the nodules yield an indeterminate result. The Afirma® gene expression classifier (AGEC) was developed to improve management of indeterminate thyroid nodules (ITNs) by classifying them as "benign" or "suspicious." Objectives were (1) to assess the performance of the AGEC in two Canadian academic medical centres (2), to search for inter-institutional variation and (3) to compare AGEC performance in Canadian versus American institutions...
April 4, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28356138/can-floseal%C3%A2-be-applied-safely-during-otologic-surgery-assessment-of-ototoxicity-in-a-chinchilla-animal-model
#17
Carol Nhan, Aren Bezdjian, Abdullah Alarfaj, Sam J Daniel
BACKGROUND: In otologic surgery good visualization is paramount, and patients with bleeding diatheses or who need to be anti-coagulated can present a significant challenge. Here, we determine whether Floseal™, a hemostatic matrix, is ototoxic in a validated animal model. METHODS: Nine chinchillas housed in the animal care facilities of the Montreal Children's Hospital Research Institute were used for the study. After a myringotomy incision was made in each tympanic membrane, baseline auditory brainstem response measurements were performed at 8, 20, and 25 kHz...
March 29, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28347329/incidence-and-burden-of-comorbid-pain-and-depression-in-patients-with-chronic-rhinosinusitis-awaiting-endoscopic-sinus-surgery-in-canada
#18
Bassem M N Hanna, R Trafford Crump, Guiping Liu, Jason M Sutherland, Arif S Janjua
BACKGROUND: This study sheds important light on the association between sino-nasal symptoms and global quality of life in patients with chronic rhinosinusitis waiting for endoscopic sinus surgery. Using patient-reported information collected pre-operatively, the primary objective was to report on patients' pre-surgical sino-nasal symptoms and their association with self-reported pain and depression. The secondary objective was to report on levels of depression and pain among patients in the sample reporting severe sleep problems...
March 27, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28320460/thyroid-incidentalomas-on-18fdg-pet-ct-a-metabolico-pathological-correlation
#19
N Hagenimana, J Dallaire, É Vallée, M Belzile
BACKGROUND: Thyroid incidentaloma is defined as an unsuspected thyroid lesion found on imaging study or while performing a surgery non-related to the thyroid gland. Most recent scientific literature tends to demonstrate a detection rate of 0.1-4.3% for incidental findings of thyroid focal uptake identified by (18)F-fluorodeoxyglugose Positron Emission Tomography with computed tomography ((18)FDG-PET/CT) initially prescribed for nonthyroid disease. From 10.3 to 80.0% of patients who underwent further evaluation are diagnosed with malignant lesions...
March 21, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28298239/associations-of-foxp3-gene-polymorphisms-with-severe-recurrent-respiratory-papillomatosis-in-korean-patients
#20
Tack-Kyun Kwon, Eun Jae Chung, Nuri Lee, Eun Youn Roh, Eun Young Song
BACKGROUND: FoxP3 is the most dependable marker for regulatory T cells which play a major role in immune tolerance. Foxp3 gene polymorphisms were associated with various autoimmune diseases and clearance of viral infections. We studied the association of Foxp3 polymorphisms in severe RRP patients. METHODS: A total of 30 Korean severe RRP patients and 195 healthy controls were enrolled. Foxp3 polymorphisms (rs5902434 del/ATT, rs3761548 C/A, rs3761549 C/T, and rs2232365 G/A) were determined by PCR and sequencing...
March 15, 2017: Journal of Otolaryngology—Head & Neck Surgery
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