Yanhui Liang, Fusheng Wang, Darren Treanor, Derek Magee, Nick Roberts, George Teodoro, Yangyang Zhu, Jun Kong
Three-dimensional (3D) high resolution microscopic images have high potential for improving the understanding of both normal and disease processes where structural changes or spatial relationship of disease features are significant. In this paper, we develop a complete framework applicable to 3D pathology analytical imaging, with an application to whole slide images of sequential liver slices for 3D vessel structure analysis. The analysis workflow consists of image registration, segmentation, vessel cross-section association, interpolation, and volumetric rendering...
2016: International Journal of Computational Biology and Drug Design