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Tuberculosis and Respiratory Diseases

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https://www.readbyqxmd.com/read/28119754/erratum-clinical-practice-guideline-of-acute-respiratory-distress-syndrome
#1
(no author information available yet)
[This corrects the article on p. 214 in vol. 79, PMID: 27790273.].
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119753/is-the-combination-of-ics-and-laba-a-therapeutic-option-for-copd-fading-away
#2
EDITORIAL
Yeon-Mok Oh
No abstract text is available yet for this article.
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119752/progression-of-tuberculous-pleurisy-from-a-lymphocyte-predominant-free-flowing-effusion-to-a-neutrophil-predominant-loculated-effusion
#3
EDITORIAL
Won-Jung Koh
No abstract text is available yet for this article.
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119751/the-impact-of-autophagy-on-the-cigarette-smoke-extract-induced-apoptosis-of-bronchial-epithelial-cells
#4
Chang-Hoon Lee, Kyoung-Hee Lee, An-Hee Jang, Chul-Gyu Yoo
BACKGROUND: Previous studies report that apoptosis and autophagy are involved in the pathogenesis of emphysema, and macroautophagy is one of the processes regulating the apoptosis pathway. However, few studies have evaluated whether chaperone-mediated autophagy (CMA) contributes to the regulation of apoptosis. In this study, we investigated the impact of autophagy, including both macroautophagy and CMA, on the apoptosis in bronchial epithelial cells. METHODS: Cigarette smoke extract (CSE) was injected intratracheally into C57BL/6 mice, and emphysema and apoptosis were evaluated in the lungs...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119750/mycobacterium-tuberculosis-esat6-and-cpf10-induce-adenosine-deaminase-2-mrna-expression-in-monocyte-derived-macrophages
#5
Mi Jung Bae, Suyeon Ryu, Ha-Jeong Kim, Seung Ick Cha, Chang Ho Kim, Jaehee Lee
BACKGROUND: Delayed hypersensitivity plays a large role in the pathogenesis of tuberculous pleural effusion (TPE). Macrophages infected with live Mycobacterium tuberculosis (MTB) increase the levels of adenosine deaminase2 (ADA2) in the pleural fluid of TPE patients. However, it is as yet unclear whether ADA2 can be produced by macrophages when challenged with MTB antigens alone. This study therefore evaluated the levels of ADA2 mRNA expression, using monocyte-derived macrophages (MDMs) stimulated with MTB antigens...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119749/health-related-quality-of-life-depression-and-anxiety-in-hospitalized-patients-with-tuberculosis
#6
Ana Paula Ceré Dos Santos, Tássia Kirchmann Lazzari, Denise Rossato Silva
BACKGROUND: Much of the attention of tuberculosis (TB) programs is focused on outcomes of microbiological cure and mortality, and health related quality of life (HRQL) is undervalued. Also, TB patients have a significantly higher risk of developing depression and anxiety compared with those in the general population. We intend to evaluate the HRQL and the prevalence of symptoms of depression and anxiety in hospitalized patients with TB. METHODS: Cross-sectional study in a tertiary care hospital in Brazil...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119748/mometasone-furoate-suppresses-pma-induced-muc-5ac-and-muc-2-production-in-human-airway-epithelial-cells
#7
Orapan Poachanukoon, Sittichai Koontongkaew, Paopanga Monthanapisut, Napaporn Pattanacharoenchai
BACKGROUND: Mucus hypersecretion from airway epithelium is a characteristic feature of airway inflammatory diseases. Tumor necrosis factor α (TNF-α) regulates mucin synthesis. Glucocorticoids including mometasone fuorate (MF) have been used to attenuate airway inflammation. However, effects of MF on mucin production have not been reported. METHODS: Effects of MF and budesonide (BUD) on the phorbol-12-myristate-13-acetate (PMA)-induction of mucin and TNF-α in human airway epithelial cells (NCI-H292) were investigated in the present study...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119747/safety-and-effectiveness-of-indacaterol-in-chronic-obstructive-pulmonary-disease-patients-in-south-korea
#8
Ho-Kee Yum, Hak-Ryul Kim, Yoon Soo Chang, Kyeong-Cheol Shin, Song Kim, Yeon-Mok Oh
BACKGROUND: Inhaled indacaterol (Onbrez Breezhaler), a long-acting β2-agonist, is approved in over 100 countries, including South Korea, as a once-daily bronchodilator for maintenance and treatment of chronic obstructive pulmonary disease (COPD). Here, we present an interim analysis of a post-marketing surveillance study conducted to evaluate the real-world safety and effectiveness of indacaterol in the Korean population. METHODS: This was an open-label, observational, prospective study in which COPD patients, who were newly prescribed with indacaterol (150 or 300 µg), were evaluated for 12 or 24 weeks...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119746/incidence-of-fever-following-endobronchial-ultrasound-guided-transbronchial-needle-aspiration
#9
Seo Yun Kim, Jin Woo Lee, Young Sik Park, Chang-Hoon Lee, Sang-Min Lee, Jae-Joon Yim, Young Whan Kim, Sung Koo Han, Chul-Gyu Yoo
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive diagnostic method for mediastinal and hilar lymphadenopathy. This study aimed to investigate the incidence of fever following EBUS-TBNA. METHODS: A total of 684 patients who underwent EBUS-TBNA from May 2010 to July 2012 at Seoul National University Hospital were retrospectively reviewed. The patients were evaluated for fever by a physician every 6-8 hours during the first 24 hours following EBUS-TBNA...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119745/loculated-tuberculous-pleural-effusion-easily-identifiable-and-clinically-useful-predictor-of-positive-mycobacterial-culture-from-pleural-fluid
#10
Yousang Ko, Changhwan Kim, Boksoon Chang, Suh-Young Lee, So Young Park, Eun-Kyung Mo, Su Jin Hong, Myung Goo Lee, In Gyu Hyun, Yong Bum Park
BACKGROUND: Isolation of M. tuberculosis (MTB) is required in cases of Tuberculous pleural effusion (TBPE) for confirming diagnosis and successful therapy based on drug sensitivity test. Several studies have focused on predictors of MTB culture positivity in TBPE. However, the clinical role of loculated TBPE as a predictor of MTB cultivation from TBPE remains unclear. The aim of this study was to examine possible predictors including loculation of TBPE of MTB culture positivity in TBPE...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119744/duration-of-pulmonary-tuberculosis-infectiousness-under-adequate-therapy-as-assessed-using-induced-sputum-samples
#11
Yousang Ko, Jeong Hwan Shin, Hyun-Kyung Lee, Young Seok Lee, Suh-Young Lee, So Young Park, Eun-Kyung Mo, Changhwan Kim, Yong Bum Park
BACKGROUND: A sputum culture is the most reliable indicator of the infectiousness of pulmonary tuberculosis (PTB); however, a spontaneous sputum specimen may not be suitable. The aim of this study was to evaluate the infectious period in patients with non-drug-resistant (DR) PTB receiving adequate standard chemotherapy, using induced sputum (IS) specimens. METHODS: We evaluated the duration of infectiousness of PTB using a retrospective cohort design. RESULTS: Among the 35 patients with PTB, 22 were smear-positive...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119743/preventing-the-transmission-of-tuberculosis-in-health-care-settings-administrative-control
#12
REVIEW
Kyung-Wook Jo
It is well established that health care workers (HCWs) have a considerably higher risk of occupationally acquired tuberculosis (TB). To reduce the transmission of TB to HCWs and patients, TB infection control programs should be implemented in health care settings. The first and most important level of all protection and control programs is administrative control. Its goals are to prevent HCWs, other staff, and patients from being exposed to TB, and to reduce the transmission of infection by ensuring rapid diagnosis and treatment of affected individuals...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119742/asthma-copd-overlap-syndrome-what-we-know-and-what-we-don-t
#13
REVIEW
Don D Sin
Approximately one in four patients with chronic obstructive pulmonary disease (COPD) have asthmatic features consisting of wheezing, airway hyper-responsiveness or atopy. The Global initiative for Asthma/Globalinitiative for chronic Obstructive Lung Disease committee recently labelled these patients as having asthma-COPD overlap syndrome or ACOS. ACOS also encompasses patients with asthma, ≥40 years of age, who have been cigarette smokers (more than 5-10 pack years) or have had significant biomass exposure, and demonstrate persistent airflow limitation defined as a post-bronchodilator forced expiratory volume in 1 second (FEV1)/forced vital capacity of <70%...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119741/lung-regeneration-therapy-for-chronic-obstructive-pulmonary-disease
#14
REVIEW
Dong Kyu Oh, You-Sun Kim, Yeon-Mok Oh
Chronic obstructive pulmonary disease (COPD) is a critical condition with high morbidity and mortality. Although several medications are available, there are no definite treatments. However, recent advances in the understanding of stem and progenitor cells in the lung, and molecular changes during re-alveolization after pneumonectomy, have made it possible to envisage the regeneration of damaged lungs. With this background, numerous studies of stem cells and various stimulatory molecules have been undertaken, to try and regenerate destroyed lungs in animal models of COPD...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/27790284/pulmonary-strongyloidiasis-masquerading-as-exacerbation-of-chronic-obstructive-pulmonary-disease
#15
Gourahari Pradhan, Priyadarshini Behera, Manoj Kumar Panigrahi, Sourin Bhuniya, Prasanta Raghab Mohapatra, Jyotirmayee Turuk, Srujana Mohanty
Pulmonary strongyloidiasis is an uncommon presentation of Strongyloides infection, usually seen in immunocompromised hosts. The manifestations are similar to that of acute exacerbation of chronic obstructive pulmonary disease (COPD). Therefore, the diagnosis of pulmonary strongyloidiasis could be challenging in a COPD patient, unless a high index of suspicion is maintained. Here, we present a case of Strongyloides hyperinfection in a COPD patient mimicking acute exacerbation, who was on chronic steroid therapy...
October 2016: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/27790283/pulmonary-leukocytoclastic-vasculitis-as-an-initial-presentation-of-myelodysplastic-syndrome
#16
Seung Hyun Lee, Jae Hyung Kim, Sejin Park, Chang Youn Won, Joo-Hyun Lee, Seong Yoon Yi, Hye Kyeong Park, Sun Hee Chang, Hoon Jung, Sung-Soon Lee, Hyeon-Kyoung Koo
Systemic vasculitis involving the lung is a rare manifestation of myelodysplastic syndrome (MDS), and secondary vasculitis is considered to have poor prognosis. A 44-year-old man presented with fever and dyspnea of 1 month duration. A chest radiograph revealed bilateral multiple wedge shaped consolidations. In addition, the results of a percutaneous needle biopsy for non-resolving pneumonia were compatible with pulmonary vasculitis. Bone marrow biopsy was performed due to the persistence of unexplained anemia and the patient was diagnosed with MDS...
October 2016: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/27790282/association-of-specific-immunoglobulin-e-to-staphylococcal-enterotoxin-with-airway-hyperresponsiveness-in-asthma-patients
#17
Seong Han Kim, Seo Yeon Yang, Jihong You, Sang Bae Lee, Jin You, Yoon Soo Chang, Hyung Jung Kim, Chul Min Ahn, Min Kwang Byun, Hye Jung Park, Jung-Won Park
BACKGROUND: Specific immunoglobulin E (IgE) sensitization to staphylococcal enterotoxin (SE) has been recently considered to be related to allergic disease, including asthma. Despite studies on specific IgE (sIgE) to SE and its relationship to asthma diagnosis and severity, the association of sIgE to SE with airway hyperresponsiveness (AHR) remains unclear. METHODS: We enrolled 81 asthma patients admitted to the Severance Hospital in Korea from March 1, 2013, to February 28, 2015 and retrospectively reviewed the electronic medical records of the enrolled subjects...
October 2016: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/27790281/the-prognostic-value-of-the-charlson-s-comorbidity-index-in-patients-with-prolonged-acute-mechanical-ventilation-a-single-center-experience
#18
Seung Eon Song, Sang Hee Lee, Eun-Jung Jo, Jung Seop Eom, Jeong Ha Mok, Mi-Hyun Kim, Ki Uk Kim, Min Ki Lee, Kwangha Lee
BACKGROUND: The aim of our study was to evaluate the prognostic value of Charlson's weighted index of comorbidities (WIC) in patients with prolonged acute mechanical ventilation (PAMV, ventilator care ≥96 hours). METHODS: We retrospectively enrolled 299 Korean PAMV patients who were admitted in a medical intensive care unit (ICU) of a university-affiliated tertiary care hospital between 2008 and 2013. Survivors were defined as patients who survived for 60 days after ICU admission...
October 2016: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/27790280/performance-of-the-bact-alert-3d-system-versus-solid-media-for-recovery-and-drug-susceptibility-testing-of-mycobacterium-tuberculosis-in-a-tertiary-hospital-in-korea
#19
Seoung-Cheol Kim, Bo-Young Jeon, Jin-Sook Kim, In Hwan Choi, Jiro Kim, Jeongim Woo, Soojin Kim, Hyeong Woo Lee, Monoldorova Sezim, Sang-Nae Cho
BACKGROUND: Tuberculosis (TB) is a major health problem, and accurate and rapid diagnosis of multidrug-resistant (MDR) and extended drug-resistant (XDR) TB is important for appropriate treatment. In this study, performances of solid and liquid culture methods were compared with respect to MDR- and XDR-TB isolate recovery and drug susceptibility testing. METHODS: Sputum specimens from 304 patients were stained with Ziehl-Neelsen method. Mycobacterium tuberculosis (Mtb) isolates were tested for recovery on Löwenstein-Jensen (LJ) medium and the BacT Alert 3D system...
October 2016: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/27790279/the-younger-patients-have-more-better-prognosis-in-limited-disease-small-cell-lung-cancer
#20
Hye-Jin Kim, Chang-Min Choi, Seul-Gi Kim
BACKGROUND: Factors associated with the prognosis of patients with small cell lung cancer (SCLC) is relatively unknown, than of those with non-small cell lung cancer. This study was undertaken to identify the prognostic factors of SCLC. METHODS: The medical records of 333 patients diagnosed with SCLC at tertiary hospital from January 1, 2008, to December 31, 2012 were retrospectively reviewed. Patients were categorized by age (≤65 years vs. >65 years) and by extent of disease (limited disease [LD] vs extensive disease [ED])...
October 2016: Tuberculosis and Respiratory Diseases
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