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Tuberculosis and Respiratory Diseases

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https://www.readbyqxmd.com/read/28416962/cutaneous-leukocytoclastic-vasculitis-with-gastrointestinal-involvement-after-anti-tuberculosis-treatment
#1
Sangwoo Shim, Chi Young Jung
No abstract text is available yet for this article.
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28416961/predictive-factors-of-methicillin-resistant-staphylococcus-aureus-infection-in-elderly-patients-with-community-onset-pneumonia
#2
Hyeyoung Jwa, Jong Wook Beom, Jong Hoo Lee
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) infection is a severe and life-threatening disease in patients with community-onset (CO) pneumonia. However, the current guidelines lack specificity for a screening test for MRSA infection. METHODS: This study was retrospectively conducted in elderly patients aged ≥65 years, who had contracted CO-pneumonia during hospitalization at the Jeju National University Hospital, between January 2012 and December 2014...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28416960/medical-thoracoscopy-in-pleural-disease-experience-from-a-one-center-study
#3
Soo Jung Kim, Sun Mi Choi, Jinwoo Lee, Chang-Hoon Lee, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young Sik Park
BACKGROUND: Medical thoracoscopy (MT) is a minimally invasive, endoscopic procedure for exploration of the pleural cavity under conscious sedation and local anesthesia. MT has been performed at the Seoul National University Hospital since February 2014. This paper summarizes the findings and outcomes of MT cases at this hospital. METHODS: Patients who had undergone MT were enrolled in the study. MT was performed by pulmonologists, using both rigid and semi-rigid thoracoscopes...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28416959/predictive-factors-for-switched-egfr-tki-retreatment-in-patients-with-egfr-mutant-non-small-cell-lung-cancer
#4
Byoung Soo Kwon, Ji Hyun Park, Woo Sung Kim, Joon Seon Song, Chang-Min Choi, Jin Kyung Rho, Jae Cheol Lee
BACKGROUND: Third-generation tyrosine kinase inhibitors of the epidermal growth factor receptor (EGFR-TKIs) have proved efficacious in treating non-small cell lung cancer (NSCLC) patients with acquired resistance resulting from the T790M mutation. However, since almost 50% patients with the acquired resistance do not harbor the T790M mutation, retreatment with first- or second-generation EGFR-TKIs may be a more viable therapeutic option. Here, we identified positive response predictors to retreatment, in patients who switched to a different EGFR-TKI, following initial treatment failure...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28416958/keratinization-of-lung-squamous-cell-carcinoma-is-associated-with-poor-clinical-outcome
#5
Hye Jung Park, Yoon-Jin Cha, Seong Han Kim, Arum Kim, Eun Young Kim, Yoon Soo Chang
BACKGROUND: Although the World Health Organization (WHO) classification of lung squamous cell carcinoma (SCC) was revised in 2015, its clinical implications for lung SCC subsets remain unclear. We investigated whether the morphologic characteristics of lung SCC, including keratinization, were associated with clinical parameters and clinical outcome of patients. METHODS: A total of 81 patients who underwent curative surgical resection of diagnosed lung SCC, were enrolled in this study...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28416957/the-need-for-a-well-organized-video-assisted-asthma-education-program-at-korean-primary-care-clinics
#6
Yee Hyung Kim, Kwang Ha Yoo, Jee-Hong Yoo, Tae-Eun Kim, Deog Kyeom Kim, Yong Bum Park, Chin Kook Rhee, Tae-Hyung Kim, Young Sam Kim, Hyoung Kyu Yoon, Soo-Jung Um, I-Nae Park, Yon Ju Ryu, Jae-Woo Jung, Yong Il Hwang, Heung Bum Lee, Sung-Chul Lim, Sung Soo Jung, Eun-Kyung Kim, Woo Jin Kim, Sung-Soon Lee, Jaechun Lee, Ki Uk Kim, Hyun Kuk Kim, Sang Ha Kim, Joo Hun Park, Kyeong Cheol Shin, Kang Hyeon Choe, Ho-Kee Yum
BACKGROUND: The purpose of this study was to assess the effect of our new video-assisted asthma education program on patients' knowledge regarding asthma and asthma control. METHODS: Adult asthmatics who were diagnosed by primary care physicians and followed for at least 1 year were educated via smart devices and pamphlets. The education sessions were carried out three times at 2-week intervals. Each education period lasted at most 5 minutes. The effectiveness was then evaluated using questionnaires and an asthma control test (ACT)...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28416956/mutations-in-streptomycin-resistance-genes-and-their-relationship-to-streptomycin-resistance-and-lineage-of-mycobacterium-tuberculosis-thai-isolates
#7
Yin Moe Hlaing, Pongsri Tongtawe, Pramuan Tapchaisri, Jeeraphong Thanongsaksrikul, Unchana Thawornwan, Buppa Archanachan, Potjanee Srimanote
BACKGROUND: Streptomycin (SM) is recommended by the World Health Organization (WHO) as a part of standard regimens for retreating multidrug-resistant tuberculosis (MDR-TB) cases. The incidence of MDR-TB in retreatment cases was 19% in Thailand. To date, information on SM resistance (SMR) gene mutations correlated to the SMR of Mycobacterium tuberculosis Thai isolates is limited. In this study, the mutations in rpsL, rrs, gidB, and whiB7 were investigated and their association to SMR and the lineage of M...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28416955/down-regulation-of-serum-high-mobility-group-box-1-protein-in-patients-with-pulmonary-tuberculosis-and-nontuberculous-mycobacterial-lung-disease
#8
Su-Young Kim, Won-Jung Koh, Hye Yun Park, Kyeongman Jeon, Soo-Youn Lee, Jae-Joon Yim, Sung Jae Shin
BACKGROUND: Recently, increased levels of high-mobility group box 1 protein (HMGB1) have been identified in various inflammatory conditions and infections. However, no studies have evaluated the HMGB1 level in nontuberculous mycobacterial (NTM) lung disease, and compared it to mycobacterial lung disease. METHODS: A total of 60 patients newly diagnosed with NTM lung disease, 44 culture-positive pulmonary tuberculosis (TB) patients, and 34 healthy controls, were included in this study...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28416954/current-status-of-fluoroquinolone-use-for-treatment-of-tuberculosis-in-a-tertiary-care-hospital-in-korea
#9
Bo Hyoung Kang, Kyung-Wook Jo, Tae Sun Shim
BACKGROUND: Fluoroquinolones are considered important substitutes for the treatment of tuberculosis. This study investigates the current status of fluoroquinolone for the treatment of tuberculosis. METHODS: In 2009, a retrospective analysis was performed at one tertiary referral center for 953 patients diagnosed with tuberculosis. RESULTS: A total of 226 patients (23.6%), who received fluoroquinolone at any time during treatment for tuberculosis, were enrolled in this study...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28416953/response-evaluation-of-chemotherapy-for-lung-cancer
#10
REVIEW
Ki-Eun Hwang, Hak-Ryul Kim
Assessing response to therapy allows for prospective end point evaluation in clinical trials and serves as a guide to clinicians for making decisions. Recent prospective and randomized trials suggest the development of imaging techniques and introduction of new anti-cancer drugs. However, the revision of methods, or proposal of new methods to evaluate chemotherapeutic response, is not enough. This paper discusses the characteristics of the Response Evaluation Criteria In Solid Tumor (RECIST) version 1.1 suggested in 2009 and used widely by experts...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28416952/asthma-and-the-risk-of-rheumatoid-arthritis-an-insight-into-the-heterogeneity-and-phenotypes-of-asthma
#11
REVIEW
Mary Claire Rolfes, Young Jun Juhn, Chung-Il Wi, Youn Ho Sheen
Asthma is traditionally regarded as a chronic airway disease, and recent literature proves its heterogeneity, based on distinctive clusters or phenotypes of asthma. In defining such asthma clusters, the nature of comorbidity among patients with asthma is poorly understood, by assuming no causal relationship between asthma and other comorbid conditions, including both communicable and noncommunicable diseases. However, emerging evidence suggests that the status of asthma significantly affects the increased susceptibility of the patient to both communicable and noncommunicable diseases...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28416951/spirometry-and-bronchodilator-test
#12
REVIEW
Yun Su Sim, Ji-Hyun Lee, Won-Yeon Lee, Dong In Suh, Yeon-Mok Oh, Jong-Seo Yoon, Jin Hwa Lee, Jae Hwa Cho, Cheol Seok Kwon, Jung Hyun Chang
Spirometry is a physiological test for assessing the functional aspect of the lungs using an objective indicator to measure the maximum amount of air that a patient can inhale and exhale. Acceptable spirometry testing needs to be conducted three times by an acceptable and reproducible method for determining forced vital capacity (FVC). Until the results of three tests meet the criteria of reproducibility, the test should be repeated up to eight times. Interpretation of spirometry should be clear, concise, and informative...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119754/erratum-clinical-practice-guideline-of-acute-respiratory-distress-syndrome
#13
(no author information available yet)
[This corrects the article on p. 214 in vol. 79, PMID: 27790273.].
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119753/is-the-combination-of-ics-and-laba-a-therapeutic-option-for-copd-fading-away
#14
EDITORIAL
Yeon-Mok Oh
No abstract text is available yet for this article.
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119752/progression-of-tuberculous-pleurisy-from-a-lymphocyte-predominant-free-flowing-effusion-to-a-neutrophil-predominant-loculated-effusion
#15
EDITORIAL
Won-Jung Koh
No abstract text is available yet for this article.
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119751/the-impact-of-autophagy-on-the-cigarette-smoke-extract-induced-apoptosis-of-bronchial-epithelial-cells
#16
Chang-Hoon Lee, Kyoung-Hee Lee, An-Hee Jang, Chul-Gyu Yoo
BACKGROUND: Previous studies report that apoptosis and autophagy are involved in the pathogenesis of emphysema, and macroautophagy is one of the processes regulating the apoptosis pathway. However, few studies have evaluated whether chaperone-mediated autophagy (CMA) contributes to the regulation of apoptosis. In this study, we investigated the impact of autophagy, including both macroautophagy and CMA, on the apoptosis in bronchial epithelial cells. METHODS: Cigarette smoke extract (CSE) was injected intratracheally into C57BL/6 mice, and emphysema and apoptosis were evaluated in the lungs...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119750/mycobacterium-tuberculosis-esat6-and-cpf10-induce-adenosine-deaminase-2-mrna-expression-in-monocyte-derived-macrophages
#17
Mi Jung Bae, Suyeon Ryu, Ha-Jeong Kim, Seung Ick Cha, Chang Ho Kim, Jaehee Lee
BACKGROUND: Delayed hypersensitivity plays a large role in the pathogenesis of tuberculous pleural effusion (TPE). Macrophages infected with live Mycobacterium tuberculosis (MTB) increase the levels of adenosine deaminase2 (ADA2) in the pleural fluid of TPE patients. However, it is as yet unclear whether ADA2 can be produced by macrophages when challenged with MTB antigens alone. This study therefore evaluated the levels of ADA2 mRNA expression, using monocyte-derived macrophages (MDMs) stimulated with MTB antigens...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119749/health-related-quality-of-life-depression-and-anxiety-in-hospitalized-patients-with-tuberculosis
#18
Ana Paula Ceré Dos Santos, Tássia Kirchmann Lazzari, Denise Rossato Silva
BACKGROUND: Much of the attention of tuberculosis (TB) programs is focused on outcomes of microbiological cure and mortality, and health related quality of life (HRQL) is undervalued. Also, TB patients have a significantly higher risk of developing depression and anxiety compared with those in the general population. We intend to evaluate the HRQL and the prevalence of symptoms of depression and anxiety in hospitalized patients with TB. METHODS: Cross-sectional study in a tertiary care hospital in Brazil...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119748/mometasone-furoate-suppresses-pma-induced-muc-5ac-and-muc-2-production-in-human-airway-epithelial-cells
#19
Orapan Poachanukoon, Sittichai Koontongkaew, Paopanga Monthanapisut, Napaporn Pattanacharoenchai
BACKGROUND: Mucus hypersecretion from airway epithelium is a characteristic feature of airway inflammatory diseases. Tumor necrosis factor α (TNF-α) regulates mucin synthesis. Glucocorticoids including mometasone fuorate (MF) have been used to attenuate airway inflammation. However, effects of MF on mucin production have not been reported. METHODS: Effects of MF and budesonide (BUD) on the phorbol-12-myristate-13-acetate (PMA)-induction of mucin and TNF-α in human airway epithelial cells (NCI-H292) were investigated in the present study...
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28119747/safety-and-effectiveness-of-indacaterol-in-chronic-obstructive-pulmonary-disease-patients-in-south-korea
#20
Ho-Kee Yum, Hak-Ryul Kim, Yoon Soo Chang, Kyeong-Cheol Shin, Song Kim, Yeon-Mok Oh
BACKGROUND: Inhaled indacaterol (Onbrez Breezhaler), a long-acting β2-agonist, is approved in over 100 countries, including South Korea, as a once-daily bronchodilator for maintenance and treatment of chronic obstructive pulmonary disease (COPD). Here, we present an interim analysis of a post-marketing surveillance study conducted to evaluate the real-world safety and effectiveness of indacaterol in the Korean population. METHODS: This was an open-label, observational, prospective study in which COPD patients, who were newly prescribed with indacaterol (150 or 300 µg), were evaluated for 12 or 24 weeks...
January 2017: Tuberculosis and Respiratory Diseases
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