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Multidisciplinary Respiratory Medicine

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https://www.readbyqxmd.com/read/27872748/hemothorax-following-lung-transplantation-incidence-risk-factors-and-effect-on-morbidity-and-mortality
#1
Aria Hong, Christopher S King, A Whitney Walter Brown, Shahzad Ahmad, Oksana A Shlobin, Sandeep Khandhar, Linda Bogar, Anthony Rongione, Steven D Nathan
BACKGROUND: Hemothorax after lung transplantation may result in increased post-operative morbidity and mortality. Risk factors for developing hemothorax and the outcomes of patients who develop hemothorax have not been well studied. METHODS: A retrospective chart review was performed on all patients who underwent lung transplantation at a single center between March 2009 and July 2014. Comparison was made between patients with and without hemothorax post-transplant...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27833748/respiratory-illness-and-air-pollution-from-the-steel-industry-the-case-of-piqui%C3%A3-de-baixo-brazil-preliminary-report
#2
Carla Valenti, Paolo Pozzi, Alessandra Busia, Roberto Mazza, Paolo Bossi, Cinzia De Marco, Ario Alberto Ruprecht, Alessandro Borgini, Roberto Boffi
BACKGROUND: This report is based on an independent study carried out by medical professionals of the Fondazione IRCCS Istituto Nazionale dei Tumori (National Cancer Institute) in Milan, Italy, and  aimed to assess the incidence of respiratory diseases in a Brazilian community (Piquiá de Baixo, in the city of Açailandia) exposed to extreme air pollution in connection to a local steel manufacturing plant. The study has the objective to contribute to the existing literature on the health risks associated with fine particle pollution (PM2...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27826444/efficacy-of-recombinant-human-soluble-thrombomodulin-for-the-treatment-of-acute-exacerbation-of-idiopathic-pulmonary-fibrosis-a-single-arm-non-randomized-prospective-clinical-trial
#3
Sho Hayakawa, Yasuo Matsuzawa, Tamako Irie, Hagino Rikitake, Noriaki Okada, Yasuo Suzuki
BACKGROUND: Coagulation abnormalities are involved in the pathogenesis of acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF). The administration of recombinant human soluble thrombomodulin (rhTM), which has both anti-inflammatory and anticoagulant activities, improves outcomes and respiratory function in patients with acute respiratory distress syndrome. Therefore, we conducted a prospective clinical study to examine the effects of rhTM on respiratory function, coagulation markers, and outcomes for patients with AE-IPF...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27822370/cost-comparison-of-asthma-treatments-in-12-week-study-caution-about-matching-and-short-observational-follow-up
#4
David B Price, Job F M van Boven, Lisa M Law, Alessandra Cifra, R Brett McQueen
In the absence of randomisation, observational studies must take extra care to create treatment groups that are comparable in terms of key characteristics. Various matching methods exist which can create sound comparisons, minimising confounding where possible. A recent observational study by Dal Negro et al. carried out a cost analysis comparing two asthma medications. They report strong conclusions which favour one treatment over the other, however they include little discussion on the limitations of their study...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27766147/the-effect-of-positive-airway-pressure-therapy-on-neurocognitive-functions-depression-and-anxiety-in-obesity-hypoventilation-syndrome
#5
Serap Argun Baris, Dilek Tuncel, Cigdem Ozerdem, Huseyin Kutlu, Tugba Onyilmaz, Ilknur Basyigit, Hasim Boyaci, Fusun Yildiz
BACKGROUND: The aim of this study is to evaluate the presence of neurocognitive dysfunctions, depression and anxiety and the effect of positive airway pressure (PAP) therapy on these alterations in Obesity Hypoventilation Syndrome (OHS) patients. METHODS: Ten healthy normal and obese controls, 10 OHS and 10 OSAS patients were included in the study. Short form-36, Beck Depression Scale and State-Trade Anxiety Inventory (STAI 1-2) were performed. Wisconsin Card Sorting Test (WCST), Montreal Cognitive Assessment Scale (MOCA), Enhanced Cued Recall (ECR) and Mini Mental Test (MMT) were used for neurocognitive evaluation...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27752310/asthma-related-deaths
#6
Gennaro D'Amato, Carolina Vitale, Antonio Molino, Anna Stanziola, Alessandro Sanduzzi, Alessandro Vatrella, Mauro Mormile, Maurizia Lanza, Giovanna Calabrese, Leonardo Antonicelli, Maria D'Amato
Despite major advances in the treatment of asthma and the development of several asthma guidelines, people still die of asthma currently. According to WHO estimates, approximately 250,000 people die prematurely each year from asthma. Trends of asthma mortality rates vary very widely across countries, age and ethnic groups. Several risk factors have been associated with asthma mortality, including a history of near-fatal asthma requiring intubation and mechanical ventilation, hospitalization or emergency care visit for asthma in the past year, currently using or having recently stopped using oral corticosteroids (a marker of event severity), not currently using inhaled corticosteroids, a history of psychiatric disease or psychosocial problems, poor adherence with asthma medications and/or poor adherence with (or lack of) a written asthma action plan, food allergy in a patient with asthma...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27729977/preliminary-study-on-the-assessment-of-visceral-adipose-tissue-using-dual-energy-x-ray-absorptiometry-in-chronic-obstructive-pulmonary-disease
#7
Francesca De Blasio, Erica P A Rutten, Emiel F M Wouters, Luca Scalfi, Francesco De Blasio, Marco A Akkermans, Martijn A Spruit, Frits M E Franssen
BACKGROUND: Visceral adipose tissue (VAT) was shown to be increased in patients with chronic obstructive pulmonary disease (COPD) compared to control subjects with comparable body mass index (BMI). Our aim was to determine the relation of VAT by dual-energy x-ray absorptiometry (DEXA) in patients with COPD by disease severity, BMI, other indices of body composition and static lung volumes. METHODS: 294 COPD patients admitted for rehabilitation were studied. Lung function, static lung volumes and body composition (i...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27708777/cough-impact-beliefs-and-expectations-from-a-national-survey
#8
Roberto W Dal Negro, Massimiliano Mazzolini, Paola Turco, Alessandro Zanasi
BACKGROUND: Cough is one of the most common discomforts affecting general population, which can disrupt subjects' quality of life due to its physical, social, and psychological effects. Aim of the study was to investigate the impact of cough and related beliefs of general population. METHODS: A cross-sectional telephone survey was carried out by means of a specific, validated questionnaire on a representative sample of Italian general population. All the interviews were carried out according to the Computer Assisted Telephone Interview (CATI) methodology by expert, professional interviewers...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27625787/lung-disease-recalling-paraseptal-emphysema-in-a-patient-with-goltz-syndrome
#9
Rosaria Cortese, Salvatore Savasta, Silvia Di Stasi, Tiziana Boggini, Chiara Trabatti, Roberto Dore, Giulia Maria Stella
BACKGROUND: Goltz syndrome is a rare, genetic disorder mainly occurring in female patients. CASE PRESENTATION: The case presented here is, to the best of our knowledge, the first description of the occurrence of lung parenchymal alterations in a young female patient affected by Goltz syndrome. Although pulmonary involvement is not known in patients affected by X-linked Goltz syndrome, the case here described is related to the even rarer autosomal form of the disease, as in this case...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27597888/dry-powder-inhalers-in-patients-with-persistent-airflow-limitation-usability-and-preference
#10
Roberto W Dal Negro, Massimiliano Povero
BACKGROUND: Inhalation devices represent per sé critical factors because they can affect the therapeutic outcomes independently of the drug used. The role of patients' usability and preference (PUP) for Dry Powder Inhalers (DPIs) is high indeed because they can influence the extent of the adherence to treatment and the therapeutic outcomes. Aim of the study was to assess and compare the PUP of three different DPIs in out-patients with persistent airflow limitation due to asthma or COPD...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27555913/cultural-and-linguistic-validation-of-the-nhq-2-questionnaire-a-specific-instrument-for-assessing-patient-s-usability-of-inhalation-devices
#11
Roberto W Dal Negro, Massimiliano Povero
BACKGROUND: An increasing number of inhalation devices are presently available in the market. They are differently characterized in terms of their handling and usability, both factors which may affect the outcomes of respiratory treatment. The assessment of the preference and the usability rate of all devices can be carried out by means of specific questionnaires. Before their use, the identification of errors due to the incorrect wording of questions included in the questionnaires, together with the trans-cultural reliability represents the main issues of their cultural and linguistic validation...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27482380/perimenstrual-asthma-from-pathophysiology-to-treatment-strategies
#12
REVIEW
Alessandra Graziottin, Audrey Serafini
The prevalence of asthma is about 9,7 % in women and 5,5 % in men. Asthma can deteriorate during the perimenstrual period, a phenomenon known as perimenstrual asthma (PMA), which represents a unique, highly symptomatic asthma phenotype. It is distinguished from traditional allergic asthma by aspirin sensitivity, less atopy, and lower lung capacity. PMA incidence is reported to vary between 19 and 40 % of asthmatic women. The presence of PMA has been related to increases in asthma-related emergency department visits, hospitalizations and emergency treatment including intubations...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27408717/obesity-systemic-and-pulmonary-complications-biochemical-abnormalities-and-impairment-of-lung-function
#13
REVIEW
Thiago Thomaz Mafort, Rogério Rufino, Cláudia Henrique Costa, Agnaldo José Lopes
Obesity is currently one of the major epidemics of this millennium and affects individuals throughout the world. It causes multiple systemic complications, some of which result in severe impairment of organs and tissues. These complications involve mechanical changes caused by the accumulation of adipose tissue and the numerous cytokines produced by adipocytes. Obesity also significantly interferes with respiratory function by decreasing lung volume, particularly the expiratory reserve volume and functional residual capacity...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27382464/most-italians-attending-a-congress-on-health-of-elderly-people-do-not-know-and-do-not-recognize-respiratory-diseases
#14
Nicola Ciancio, Claudio M Sanguinetti, Franco Falcone, Claudio Taranto, Roberto Fasani, Fernando De Benedetto, Onofrio Resta, Fausto De Michele, Roberto Messina, Andrea Rossi, Stefano Nardini, Giuseppe Di Maria
BACKGROUND: The present study reports the results of a survey jointly carried out by three Italian respiratory scientific associations (AIMAR, AIPO, SIMeR) together with an important Federation of elderly patients (FederAnziani) during the National Conference of Italian Court for Health Right held in Rimini from November 29(th) to December 1(st), 2013. The survey, based on a spirometric examination preceded by a questionnaire on respiratory health, was conducted on elderly people coming from all Italian regions to attend the Conference...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27382463/high-bacterial-load-of-indoor-air-in-hospital-wards-the-case-of-university-of-gondar-teaching-hospital-northwest-ethiopia
#15
Zemichael Gizaw, Mulat Gebrehiwot, Chalachew Yenew
BACKGROUND: The air inhaled by people is abundantly populated with microorganisms which also are called bioaerosols. Bioaerosols is a colloidal suspension, formed by liquid droplets and particles of solid matter in the air, whose components contain or have attached to them viruses, fungal spores and conidia, bacterial endospores, plant pollen and fragments of plant tissues. They account for 5-34 % of indoor air pollution. METHODS: A cross-sectional study was conducted to assess the bacteriological concentration and to identify specific species of bacteria in the indoor air of Gondar University teaching hospital...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27358732/sarcoidosis-with-prevalent-and-severe-joint-localization-a-case-report
#16
Livio G Moccia, Sabrina Castaldo, Emanuela Sirignano, Maddalena Napolitano, Enrica Barra, Alessandro Sanduzzi
BACKGROUND: Sarcoidosis is a systemic granulomatous disease of unknown origin, characterized by the formation of granulomas without central necrosis. Each organ and tissue can be affected by the disease, but in most cases mainly the lungs and mediastinal lymph nodes but also skin, heart, eyes and joints are involved, the latter are mainly the metacarpophalangeal joints and bone lesions are often associated with involvement of the overlying skin. The diagnosis is often of exclusion, based on clinical and radiological suspicion, and should be confirmed by biopsy, although in each case it is necessary to exclude other possible causes of granulomatosis, including infections by mycobacteria...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27326370/evaluation-of-the-rapid-immunochromatographic-odk0501-assay-for-streptococcus-pneumoniae-antigen-detection-with-nasopharyngeal-swabs-preliminary-report
#17
Shoji Suzuki, Naoki Nishimura, Torahiko Jinta, Yasuhiko Yamano, Genta Ishikawa, Yutaka Tomishima, Noboru Uchiyama, Naohiko Chohnabayashi
BACKGROUND: Early identification and control of pathogenic bacteria are important in the treatment of pneumonia. Currently, two rapid antigen detection kits for pneumococcal pneumonia are available: one uses urine samples and the other, named RAPIRUN® S. pneumoniae, uses sputum samples. RAPIRUN® has shown high sensitivity with nasopharyngeal swab samples from pediatric patients. In this study, we investigated the performance of RAPIRUN® with nasopharyngeal swabs from adult patients...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27298726/prospective-study-of-the-efficacy-of-antibiotics-versus-antitussive-drugs-for-the-management-of-urti-related-acute-cough-in-children
#18
Alessandro Zanasi, Luigi Lanata, Federico Saibene, Giovanni Fontana, Peter V Dicpinigaitis, Valentina Venier, Francesco De Blasio
BACKGROUND: Acute cough is one of the most frequent symptoms prompting a visit to a health care provider, usually following a viral upper respiratory tract infection (URTI). The disproportionate use of antibiotics in children with URTIs, recently highlighted in the medical literature, could lead to associated side effects, without any beneficial effect. Although an early, albeit inappropriate, antibiotic prescription increases parental satisfaction, URTIs are predominantly viral infections and are generally self-limiting...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27280021/need-of-education-for-dry-powder-inhaler-storage-and-retention-a-patient-reported-survey
#19
Birger Norderud Lærum, Gunilla Telg, Georgios Stratelis
BACKGROUND: Dry powder inhalers (DPIs) are the most commonly used devices in asthma treatment in the Nordic countries. As new DPIs become available, patients are likely to be exposed to more than one type of device, with variable optimal handling. The aim was to examine real life storage and retention of multidose DPIs in patients with asthma. METHODS: This patient-reported survey on real life storage and retention of DPIs included asthma patients using multidose DPIs...
2016: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/27275384/fluticasone-furoate-vilanterol-92-22%C3%A2-%C3%AE-g-once-a-day-vs-beclomethasone-dipropionate-formoterol-100-6%C3%A2-%C3%AE-g-b-i-d-a-12-week-cost-analysis-in-mild-to-moderate-asthma
#20
Roberto W Dal Negro, Chiara Distante, Luca Bonadiman, Paola Turco, Sergio Iannazzo
BACKGROUND: Asthma is a disease with high cost for the National Health Service. Two of the most recent LABA/ICS combinations for persistent bronchial asthma are Beclomethasone dipropionate/Formoterol (B/F) delivered via the Nexthaler device and Fluticasone furoate/Vilanterol (F/V) delivered via the Ellipta device. No comparison has been carried out yet in terms of cost analysis in asthma, to our knowledge. Aim of the present monocentric, observational, retrospective study was to calculate and compare the costs of mild-to-moderate asthma patients assuming B/F 100/6 μg b...
2016: Multidisciplinary Respiratory Medicine
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