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Journal of Medicine and Life

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https://www.readbyqxmd.com/read/28255388/the-evaluation-of-the-oxidative-stress-for-patients-receiving-neoadjuvant-chemoradiotherapy-for-locally-advanced-rectal-cancer
#1
G L Serbanescu, M I Gruia, M Bara, R M Anghel
Hypothesis: Nowadays, rectal cancer is an important healthcare challenge that affects many thousands of people each year worldwide, being diagnosed especially after the age of 50 years. Objective: This study attempted to evaluate the oxidative stress in patients with rectal cancer. Methods and results: 30 patients from the "Prof. Dr. Al. Trestioreanu" Institute of Oncology in Bucharest were treated with neoadjuvant radiochemotherapy during 2014 and 2016 and were included in the clinical study. Blood samples were obtained in dynamics during the treatment...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255387/reverse-sural-flap-for-ankle-and-heel-soft-tissues-reconstruction
#2
R N Ciofu, D G Zamfirescu, S A Popescu, I Lascar
Introduction: The potential of the medial calf integument, as donor site for a free flap based on musculocutaneous branches of the medial sural artery, was first identified by Taylor and Daniel, following cadaver investigation. In 1981, Pontén described the fasciocutaneous sural flap as a reconstructive option for soft tissue loss of the lower extremity, particularly around the knee. Two years later, Donski and Fogdestram presented the distally based fasciocutaneous flap from the sural region followed by Montegut and Allen who considered the sural artery perforator flap as a viable alternative for the gastrocnemius myocutaneous flap...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255386/variation-in-uterus-position-prior-to-brachytherapy-of-the-cervix-a-case-report
#3
M T Georgescu, R Anghel
Rationale: brachytherapy is administered in the treatment of patients with locally advanced cervical cancer following chemoradiotherapy. Lack of local anatomy evaluation prior to this procedure might lead to the selection of an inappropriate brachytherapy applicator, increasing the risk of side effects (e.g. uterus perforation, painful procedure ...). Objective: To assess the movement of the uterus and cervix prior to brachytherapy in patients with gynecological cancer, in order to select the proper type of brachytherapy applicator...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255385/reelin-and-its-receptors-vldlr-and-apoer2-in-melanocytic-nevi
#4
A Mihail, G Coman, F Staniceanu, L Coman, S Zurac, O A Coman
Reelin is an extracellular signaling protein synthesized by Cajal-Retius cells in utero and early after birth, its presence being signaled in adult life too. Reelin acts on its receptors, VLDLR and ApoER2, acting on cytoskeleton, controlling migration and subsequently positioning and stabilizing the cortical neurons. We investigated the reelin presence and its receptors, VLDLR and ApoER2, in melanocytic nevi considering the neural crest origin of the nevus cells and their migration into skin during embrionary period...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255384/the-cellular-and-humoral-immunity-assay-in-patients-with-complicated-urolithiasis
#5
E Ceban, P Banov, A Galescu, D Tanase
Especially complicated, renal lithiasis contributes to the general inflammatory syndrome development that interferes with nonspecific, humoral and cellular immune system. The surgical treatment of nephrolithiasis is closely related to drug therapy of urinary infection, one of the reasons being the reduction of the immune status. The work is performed by evaluating the immunological status preoperatively in 58 patients with complicated lithiasis. The analysis of the status in these patients demonstrated that complicated urolithiasis results in significant changes in the immune system, these changes being expressed at the cellular and humoral level of immunity...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255383/subserosal-hematoma-of-the-sigmoid-colon-after-vaginal-delivery
#6
N Bacalbașa, R E Bohîlțea, M Dumitru, N Turcan, M M Cîrstoiu
Postpartum hemorrhage is an obstetrical emergency that represents the leading cause of maternal mortality. Severe hemorrhagic complications that could appear postpartum are the abdomino-pelvic hematomas, which result from the rupture of the pelvic vessels. We reported a very rare case of puerperal retroperitoneal subserosal hematoma of sigmoid colon following vaginal delivery, which was successfully managed by conservative methods. As far as we know, there are only a few case reports of intramural hematoma of sigmoid colon in literature, having other etiologies than vaginal delivery trauma...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255382/clinical-radiological-aspects-of-primary-endodontic-lesions-with-secondary-periodontal-involvement
#7
R Jivoinovici, Ileana Suciu, I Gheorghiu, Ioana Suciu
Damage of pulp tissue usually begins in the coronal pulp. Its mistreatment or its lack of on time detection determines the progressive inclusion of the whole endodontic space in its evolution, opening the way of its expansion in the surrounding tissues of the tooth, and on the marginal apical tissue. Aim. The goal of this study was to highlight that the primary endodontic lesions with secondary periodontal implication healed and bone repair was obtained due to a proper disinfection and an adequate sealing of the endodontic system...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255381/can-endobronchial-or-endotracheal-metastases-appear-from-rectal-adenocarcinoma
#8
G L Serbanescu, R M Anghel
Background: Endobronchial and endotracheal metastases from extra-pulmonary solid tumors are rare. Patients and methods: We reported the case of a patient diagnosed with endobronchial and endotracheal metastases from rectal adenocarcinoma. Case report: Patient P.G., 62 years old, was diagnosed with a rectal tumor in 2011, for which, a surgical intervention was performed (pT3 pN2a M0, stage IIIB). Afterwards, she underwent adjuvant chemotherapy and concomitant radiochemotherapy. In September 2013, the chest CT showed 2 nodules for which, an incomplete surgical resection was done and which were histopathologically diagnosed as metastases from rectal cancer...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255380/aspects-of-communication-in-medical-life-doctor-patient-communication-differentiation-and-customization
#9
D Borţun, C S Matei
One of the weaknesses of the Romanian medical system is the absence of the communicational culture. This absence is felt at all levels of the healthcare system: doctor-patient relationship, doctor-patient's relatives relationship, labor relations within the medical teams and units, the management of the large hospitals and of the medical institutions from the public administration system and last, but not least, the relationships of these units and institutions with the public opinion and, particularly, with the stakeholders...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255379/medical-legislation-educational-needs-assessment-for-dental-students
#10
S M Piţuru, A Nanu, A Bucur
Rationale (hypothesis): Many studies have highlighted the vulnerabilities in medical practice due to the legislation ignorance. Therefore, developing special programs for students training is needed and has become imperative. Objective: This research aimed to identify the educational needs for the 5th year students in "Carol Davila" School of Dentistry in Bucharest, related to the legislation in dentistry and its area of application. Methods and results: 199 students were invited to respond to a specially designed questionnaire...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255378/immunotherapy-and-gene-therapy-in-prostate-cancer-treatment
#11
T Grozescu, F Popa
There are few methods bringing several relatively recent advances in therapy of certain types of prostate cancer. Belonging to personalized therapies, they use cells (normal or pathologic) from the patient, modify and reintroduce them in the patient's body, leading to an increased efficiency against the neoplastic tissue, proving to increase the patient's lifespan and/ or tumor progression.
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255377/pathophysiological-changes-of-inflammatory-syndrome-in-multiple-sclerosis-after-instituting-therapeutic-plasmapheresis
#12
S Vlaic, V Poalelungi, M Bălăeţ, V L Purcărea, C Bălăeţ, B I Coculescu
In autoimmune conditions affecting the central and peripheral CNS as well as in multiple sclerosis (MS), the inflammatory syndrome is present with the onset of this disease. The present paper aimed to highlight the inflammatory syndrome based on the leukergia test, the total blood viscosity test, blood filterability test as well as on other tests. The early instituting of the therapeutic plasmapheresis beneficially modified the clinical status, the biological and pathophysiological behavior of the patient's illness...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255376/serious-mistakes-in-meta-analysis-of-homeopathic-research
#13
G Vithoulkas
The article discussed the immanent problems of meta-analyses selecting a number of independent trials in homeopathy, within which, the purpose was to examine the effectiveness of homeopathic treatment. Our focus lied in clarifying that the complex effects of homeopathic treatment known from history and day-to-day practice have not been respected so far. The examination of most of the homeopathic trials showed that studies rarely account for homeopathic principles, in order to assess the effectiveness of the treatment...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255375/the-adaptation-of-health-care-marketing-to-the-digital-era
#14
G Radu, M Solomon, C M Gheorghe, M Hostiuc, I A Bulescu, V L Purcarea
The purpose of health care marketing is to learn and understand the needs and desires of prospective patients in order to be able to meet those necessities at the highest standards. A big advantage is the targeting capability of the electronic media that has led to its being used by managers of marketing in medical institutions as means of advertisement when they develop the marketing strategies. Regarding social media, it is safe to say that there are communication platforms that can promote certain behaviours thus influencing decision-making...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255374/comparison-of-health-seeking-characteristics-of-german-and-belgian-university-students
#15
COMPARATIVE STUDY
R Koop, H Kartounian, D Devroey
Introduction. The aim of this study was to determine whether the use of primary health care differs between students enrolled in Belgian and German government-funded universities. The secondary aim of the study was to determine the factors that might explain such a difference. Methods. Participants were recruited through all Belgian and German government-funded universities. Because not all the universities agreed to participate, recruiting was also done through social media groups of the universities. An anonymous online survey was used for data collection...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255373/effect-of-rhythmic-auditory-stimulation-on-gait-kinematic-parameters-of-patients-with-multiple-sclerosis
#16
REVIEW
M Shahraki, M Sohrabi, H R Taheri Torbati, K Nikkhah, M NaeimiKia
Purpose: This study aimed to examine the effect of rhythmic auditory stimulation on gait kinematic parameters of patients with multiple sclerosis. Subjects and Methods: In this study, 18 subjects, comprising 4 males and 14 females with Multiple Sclerosis with expanded disability status scale of 3 to 6 were chosen. Subjects were selected by available and targeted sampling and were randomly divided into two experimental (n = 9) and control (n = 9) groups. Exercises were gait with rhythmic auditory stimulation by a metronome device, in addition to gait without stimulation for the experimental and control groups, respectively...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255372/upper-gastrointestinal-endoscopy-in-emergency-setting-for-patients-receiving-oral-anticoagulants-practice-updates
#17
REVIEW
R Oprita, B Oprita, B Diaconescu, M R Bratu, D Berceanu
Anticoagulants are frequently used medications in diverse cardiovascular diseases. Their uses highly increase the risk of bleeding from upper and lower gastrointestinal sources, whether there is a classic vitamin K antagonist or a novel oral anticoagulant. Their interruption can promote procoagulation status with different thromboembolic accidents. Discontinuation of oral anticoagulants before the elective procedures is standardized but there are no guidelines for managing bleeding lesions of upper gastrointestinal tract concomitant with anticoagulation...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255371/non-invasive-imaging-techniques-in-assessing-non-alcoholic-fatty-liver-disease-a-current-status-of-available-methods
#18
REVIEW
A M Lăpădat, I R Jianu, B S Ungureanu, L M Florescu, D I Gheonea, S Sovaila, I A Gheonea
Non-alcoholic fatty liver disease (NAFLD) is an ailment affecting and increasing a number of people worldwide diagnosed via non-invasive imaging techniques, at a time when a minimum harm caused by medical procedures is rightfully emphasized, more sought after, than ever before. Liver steatosis should not be taken lightly even if its evolution is largely benign as it has the potential to develop into non-alcoholic steatohepatitis (NASH) or even more concerning, hepatic cirrhosis, and hepatocellular carcinoma (HCC)...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255370/erectile-dysfunction-post-radical-prostatectomy-a-challenge-for-both-patient-and-physician
#19
REVIEW
O Bratu, I Oprea, D Marcu, D Spinu, A Niculae, B Geavlete, D Mischianu
Post-radical prostatectomy erectile dysfunction (post RP ED) is a major postoperative complication with a great impact on the quality of life of the patients. Until present, no proper algorithm or guideline based on the clinical trials has been established for the management of post RP ED. According to literature, it is better to initiate a penile rehabilitation program as soon as possible after surgery than doing nothing, in order to prevent and limit the postoperative local hypoxygenation and fibrosis. The results of numerous clinical trials regarding the effectiveness of the phosphodiesterase 5 inhibitors therapy on post RP ED have made them the gold standard treatment...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28255369/prostate-cancer-between-prognosis-and-adequate-proper-therapy
#20
REVIEW
T Grozescu, F Popa
Knowing the indolent, non-invasive nature of most types of prostate cancer, as well as the simple fact that the disease seems more likely to be associated with age rather than with other factors (50% of men at the age of 50 and 80% at the age of 80 have it [1], with or without presenting any symptom), the big challenge of this clinical entity was to determine severity indicators (so far insufficient) to guide the physician towards an adequate attitude in the clinical setting. The risk of over-diagnosing and over-treating many prostate cancer cases (indicated by all the major European and American studies) is real and poses many question marks...
January 2017: Journal of Medicine and Life
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