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Journal of Medicine and Life

A A Zulfiqar, E Andres
OBJECTIVE: To investigate the association between pernicious anemia and other autoimmune diseases. METHODS: This retrospective and bicentric study was conducted at Reims and Strasbourg University Hospitals and involved 188 patients with pernicious anemia examined between 2000 and 2010 in order to search for other autoimmune diseases and to evaluate the role of pernicious anemia in autoimmune polyglandular syndrome. RESULTS: A total of 74 patients with a combination of pernicious anemia and other autoimmune diseases were included in the study...
October 2017: Journal of Medicine and Life
S Yadollah, N Kazemipour, S Bakhtiyari, S Nazifi
HYPOTHESIS: Palmitate causes insulin resistance (IR) in insulin target tissue. Pioglitazone (an anti-hyperglycemic agent) and epigallocatechin gallate (EGCG, a dietary supplement) can be used for the treatment of type 2 diabetes. However, their molecular effects on gluconeogenesis remain unclear. OBJECTIVE: Hence, we aimed to investigate the simultaneous effect of these anti-hyperglycemic agents on gluconeogenesis through in vitro experiments. METHODS: HepG2 cells were treated with 0...
October 2017: Journal of Medicine and Life
M P Acosta-Rios, E Sauer-Ramírez, L J Castro-Muñoz, M García-Solís, C Gómez-García, R Ocadiz-Delgado, A Martinez-Martinez, V Sánchez-Monroy, C Pérez-De la Mora, B Correa-Meza, D G Perez-Ishiwara
The objective of the study was to assess the clinical, histopathological and immunochemical changes induced by dialyzable leukocyte extract (DLE) treatment in patients with chronic cervicitis associated to HPV infection. Fifty-four female Mexican patients diagnosed with chronic cervicitis, cervical intra-epithelial neoplasia grade 1 (CIN 1) and HPV infection were divided into two groups: patients treated with placebo and patients treated with DLE. Clinical and colposcopy evaluations were performed before and after treatments...
October 2017: Journal of Medicine and Life
R Covali
RATIONALE: Hysterosalpingography is still the main method to begin with when studying the causes of female impossibility to conceive a baby. OBJECTIVE: The aim of this study is to correlate and evaluate the wide range of tubal pathology discovered by routine hysterosalpingography in a university hospital in Romania with the successful pregnancy rate. METHODS AND RESULTS: A total of 95 consecutive patients explored by routine hysterosalpingography in a university hospital during 2015 and 2016 were included...
October 2017: Journal of Medicine and Life
J Q Franco-Aguirre, A A Cardona-Tapias, J A Cardona-Arias
PURPOSE: To compare Health-Related Quality of Life (HRQOL) profiles and their associated factors in people with rheumatoid arthritis (RA), spondyloarthritis (SpA), fibromyalgia (FM) and rheumatoid comorbidity treated in a specialized health center (SHC) in Medellin, Colombia. METHODS: A cross-sectional analytical study was performed with 93 RA patients, 30 SpA patients, 41 primary FM patients and 48 secondary FM patients with a concurrent diagnosis of RA or SpA...
October 2017: Journal of Medicine and Life
A Stan, C Birle, A Blesneag, M Iancu
Background - Stroke represents one of the most important causes of permanent physical or mental disability. A number of recent advances in recovery have reinforced the idea that pharmacological intervention combined with a specific rehabilitation therapy can reduce disability after stroke. Objective - The aim of this trial was to demonstrate the hypothesis that the association of pharmacological treatment with Cerebrolysin to early physical therapy can significantly stimulate the endogenous processes underlying the recovery after an ischemic stroke...
October 2017: Journal of Medicine and Life
R Soleimani, M M Jalali, A Keshtkar, S M Jalali
INTRODUCTION: Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder that causes significant distress to the afflicted individual. About half of OCD patients treated with an adequate trial of serotonin reuptake inhibitors fail to fully respond to treatment and continue to exhibit significant symptoms. Therefore, there is a need for other agents to alleviate the symptoms of these disorders. In spite of considerable research including numerous randomized controlled trials and systematic reviews, there exists uncertainty regarding what treatments are effective...
October 2017: Journal of Medicine and Life
R Opriţă, B Opriţă, D Berceanu, I B Diaconescu
Rationale (hypothesis): IgG4-related disease (IgG4-RD) is a pathological entity recently recognized by the medical world that can affect any organ or system. However, there is insufficient data about this disease in medical literature. Aim (objective): A more extensive clarification of the IgG4 molecule, the diversified aspects of IgG4-related disease, and the response of this disease to treatment, will provide a crucial understanding of the immune system and other diseases now known to be associated with IgG4...
October 2017: Journal of Medicine and Life
V L Purcarea
No abstract text is available yet for this article.
October 2017: Journal of Medicine and Life
G Vithoulkas
No abstract text is available yet for this article.
July 2017: Journal of Medicine and Life
A Zamfir-Chiru-Anton, A E Stanciu, D C Gheorghe
Cricoid malformations vary according to their severity and anatomic features. Some of them get a delayed diagnosis in spite of the complex medical care. Objective: To present a case with a laryngeal malformation and our surgery technique. Material, method: A case presentation of a cannulated child, who previously had a heart surgery, with difficult decannulation. RESULTS: The patient was considered to have an acquired subglottic stenosis due to his medical record. A cricoid cartilage malformation was elicited intraoperatively...
July 2017: Journal of Medicine and Life
P Banov, E Ceban
Urolithiasis is a significant social and financial problem. According to contemporary literature data, 1-5% of the global population suffers from urolithiasis. The prevalence of this disease is about 10% of the population of the Republic of Moldova. Scientific and practical researches in the field of urology, and especially those devoted to renal lithiasis, focus on the diagnosis and treatment process, giving little importance to the cause of formation, metabolic disturbances, and especially to prophylaxis and metaphylaxis of the disease recurrence...
July 2017: Journal of Medicine and Life
V Akhavan Zanjani, K Tabari, S M Sheikh-Al-Eslamian, A N Abrandabadi
Introduction: Development of new pulp capping agents has paved the way towards the preservation of pulp vitality, which is an important goal in restorative dentistry. This study sought to assess the calcium ion release, pH and setting of mineral trioxide aggregate (MTA) Angelus, an experimental formulation of nano-hybrid MTA containing nano-SiO2, nano-Al2O3 and nano-TiO2 and MTA Angelus plus nano-oxides. Methods: In this experimental study, five specimens from each material were placed in polypropylene tubes and immersed in a flask containing deionized distilled water...
July 2017: Journal of Medicine and Life
Y Bakar, Ö C Özdemir, S Sevim, E Duygu, A Tuğral, M Sürmeli
Hypothesis: Circumference measurement of extremities that was reported to be a reliable method as long as being standardized is commonly used both in clinical and home settings by clinicians or caregivers due to its cheapness and easy use. Objectives: The aims of this study were to determine the inter-observer and intra-observer reliability of manual circumference measurement among different observers and various measurement points. Methods and Results: A total of 58 lower limbs were included in the study. Both lower limbs of each subject were assessed by 6 observers randomly using circumference measurement method from 9 reference points specified with a Leg-O-Meter...
July 2017: Journal of Medicine and Life
G Marin, H Bruzzoni-Giovanelli, G Schinella
RATIONALE: RAS-RAF-MEK-ERK pathway has been considered a promising target for anticancer therapy. However, tumor cells may develop resistance against such drugs via hyperactivation of N-Ras, which explains why novel therapeut-ic approaches. In this sense, the Institute Curie- Université Pierre et Marie Curie (Paris 6) designed peptides in order to disturb Ras/Raf interaction which showed pro-apoptotic properties. These peptides were patented as WO2015001045 A2 (PCT/EP2014/064243)5. OBJECTIVE: In order to check the anti-tumoral action of WO2015001045 A2 peptides in a very aggressive BALB/c mice spontaneous leukemia called LB, we performed the present study...
July 2017: Journal of Medicine and Life
S Ilut, A Stan, A Blesneag, V Vacaras, S Vesa, L Fodoreanu
AIM: The aim of this paper was to investigate whether the extent of neurological impairment, the location of ischemic lesions due to stroke are associated with the severity of post-stroke depression. MATERIALS AND METHODS: The study included 82 patients, who were diagnosed with acute ischemic stroke and post-stroke depression and were admitted to the Neurology Clinic of Cluj-Napoca County Emergency Hospital between 2009 and 2011. A head MRI was performed with a 1...
July 2017: Journal of Medicine and Life
R M Martinez
AIM: This study assessed the efficacy of Cerebrolysin on post-stroke spasticity, motor recovery, and global functions in an outpatient rehabilitation setting. METHODS: In this retrospective comparison study, Cerebrolysin was administered at a daily dosage of 10 ml for over 30 days as an intramuscular injection. Control patients did not receive Cerebrolysin. All the patients participated in a standardized physical and occupational rehabilitation therapy for one month at least two times per week...
July 2017: Journal of Medicine and Life
K Gharagozli, A A Harandi, S Houshmand, N Akbari, D F Muresanu, J Vester, S Winter, H Moessler
Background and Purpose : The aim of this study was to evaluate the efficacy, safety, and tolerability of cerebrolysin in the early recovery phase after acute ischemic stroke. Methods. This prospective, randomized, double-blinded, placebo-controlled, multicenter, parallel-group study enrolled a total of 100 patients within 18 h after the onset of stroke. The patients were treated with Cerebrolysin (30 mL over seven days followed by 10 mL until day 30) or placebo once daily over a period of four weeks. Efficacy was primarily assessed by the NIH Stroke Scale at day 30, and additional parameters included the modified Rankin Scale, the Clinical Global Impression, the Patient Global Satisfaction (PGS) and the Mini Mental State Examination (MMSE)...
July 2017: Journal of Medicine and Life
V L Purcarea
No abstract text is available yet for this article.
July 2017: Journal of Medicine and Life
D Anyfantakis, E K Symvoulakis, S Kastanakis
No abstract text is available yet for this article.
April 2017: Journal of Medicine and Life
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