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Patient Preference and Adherence

Jing Li, Virasakdi Chongsuvivatwong, Sawitri Assanangkornchai, Edward B McNeil, Le Cai
Background: China is in an epidemiologic transition period. Health system responsiveness (HSR) has become an increasing concern in China. With the burden of increasing human immunodeficiency virus (HIV) infection/acquired immune deficiency syndrome, responsiveness of HIV care is urgently needed. We aimed at comparing the experience of HSR between HIV-positive and non-HIV patients. Methods: A cross-sectional study was carried out in Yunnan, China, from January to February 2015 among two consecutive groups of HIV and non-HIV patients in two hospitals with the largest HIV admissions...
2018: Patient Preference and Adherence
Karen Schreiber, Matthias Kant, Claudia Pfleger, Henrik Boye Jensen, Ole Oesterberg, Anne Rieper Hald, Frederik K Nielsen, Sune Rubak
Purpose: Treatment adherence is a prerequisite for treatment success and therefore an important consideration to assure that therapeutic goals are achieved both from a patient point of view and for optimal health care resource utilization. Published data on treatment adherence with fingolimod (Gilenya® ) are limited. Therefore, this study investigated treatment adherence in patients with relapsing-remitting multiple sclerosis (RRMS) treated with fingolimod in Denmark. Patients and methods: This was a 24-month, multicenter, open-label study, investigating treatment adherence, satisfaction, motivation, and health-related quality of life (QoL) in RRMS patients treated with fingolimod...
2018: Patient Preference and Adherence
Katja Goetz, Karolin Hahn, Jost Steinhäuser
Background: The evaluation of quality of primary health care from the perspective of refugees is very underdeveloped. It depends mainly on the availability of instruments in the language of the refugees. The aim of this study was to translate, culturally adapt, and examine the psychometric properties especially the internal consistency and convergent construct validity of the Arabic version of the European Project on Patient Evaluation of General Practice Care (EUROPEP) questionnaire...
2018: Patient Preference and Adherence
Edita Lycholip, Ina Thon Aamodt, Irene Lie, Toma Šimbelytė, Roma Puronaitė, Hans Hillege, Arjen de Vries, Imke Kraai, Anna Stromberg, Tiny Jaarsma, Jelena Čelutkienė
Introduction: Self-care is an important patient-reported outcome (PRO) for heart failure (HF) patients, which might be affected by disease management and/or telemonitoring (TM). The number of studies reporting the influence of TM on self-care is limited. Aims: This study aimed: to assess whether TM, in addition to information-and-communication-technology (ICT)-guided disease management system (ICT-guided DMS), affects self-care behavior; to evaluate the dynamics of self-care during the study; to investigate factors contributing to self-care changes; and to identify a patient profile that predisposes the patient to improvement in self-care...
2018: Patient Preference and Adherence
Rob Horne, Adelin Albert, Caroline Boone
Objective: In patients with rheumatoid arthritis (RA), nonadherence to treatment is often related to patients' beliefs and concerns regarding their medication. This study aimed to analyze the correlations regarding patients' medication beliefs, medication adherence, and objective measures of disease activity and safety in patients with RA established on subcutaneous (SC) anti-tumor necrosis factor α (TNFα) therapy. Methods: This Phase IV, noninterventional, non-drug-specific study enrolled patients with RA being treated with stable-dose SC anti-TNFα (adalimumab, etanercept, golimumab, and certolizumab pegol)...
2018: Patient Preference and Adherence
Camelia Rohani, Maryam Sedaghati Kesbakhi, Jamileh Mohtashami
Background: Empathy is one of the most important communication skills in clinical practice, specifically in the field of oncology. Empathic competences have a significant meaning for caring and therapeutic relations in nurses' responsibilities. Clinical empathy brings positive performance, thus patients' emotions are perceived and expressed more easily. Clinical empathy is contextual, interpersonal and affective, but it is also difficult to study. Awareness of oncology nurses' perception of this phenomenon might help them to plan for more effective patient-centered consultations within interventional programs...
2018: Patient Preference and Adherence
Evan W Davies, Samuel Llewellyn, Amélie Beaudet, Charlotte E Kosmas, Wendy Gin-Sing, Helen A Doll
Introduction: Pulmonary arterial hypertension (PAH) is a rare, incurable disease associated with decreased life expectancy and a marked impact on quality of life (QoL). There are three classes of drugs available for treatment: endothelin receptor antagonists (ERA), drugs acting on nitric oxide pathway (riociguat and phosphodiesterase type 5 inhibitors [PDE5i]), and drugs acting on prostacyclin pathway. The latter have widely different modes of administration - continuous intravenous infusion, continuous subcutaneous infusion, inhaled, and oral - each associated with variable treatment burden, and implications for health economic assessment...
2018: Patient Preference and Adherence
Markus Messerli, Noortje Vriends, Kurt E Hersberger
Background: Since 2010, Swiss pharmacists have been offering their patients a Polymedication Check (PMC), a new cognitive pharmacy service in the form of a medication review for patients taking ≥4 prescribed medicines for a period >3 months. While a first publication of this project reported on the impact of the PMC on patients' adherence, the present paper focuses on humanistic outcomes. Methods: This randomized controlled trial was conducted in 54 Swiss community pharmacies...
2018: Patient Preference and Adherence
Rozana Valiji Bharmal, Ama Johal
Background: The aim of the study was to develop a high-quality valid patient information website with regard to hypodontia and its management, and to test its effectiveness in delivering this information. Methods: A patient-based hypodontia website was created and placed on the Trust's website. It was then validated using five website assessment tools: Flesch reading ease score, LIDA, DISCERN, Journal of American Medical Association and Health on the Net seal. A cross-sectional prospective design was adopted using a 15-item questionnaire to assess the effectiveness of the newly created hypodontia website in helping participants understand their management...
2018: Patient Preference and Adherence
Pauline Roux, Filipa Pereira, Marie Santiago-Delefosse, Henk Verloo
Background: Switzerland's aging population raises pressing questions about maintaining older adults in their home environments and the problems associated with managing complex treatments requiring medication in such contexts. Few studies have examined older adults' experiences of changes in their medication on discharge home following hospitalization for illness or an accident. Similarly, few studies have evaluated the involvement of informal and professional caregivers in the medication practices used with older adults living at home...
2018: Patient Preference and Adherence
Pierre Michel, Karine Baumstarck, Anderson Loundou, Badih Ghattas, Pascal Auquier, Laurent Boyer
Background: The aim of this study was to propose an alternative approach to item response theory (IRT) in the development of computerized adaptive testing (CAT) in quality of life (QoL) for patients with multiple sclerosis (MS). This approach relied on decision regression trees (DRTs). A comparison with IRT was undertaken based on precision and validity properties. Materials and methods: DRT- and IRT-based CATs were applied on items from a unidi-mensional item bank measuring QoL related to mental health in MS...
2018: Patient Preference and Adherence
Parya Saberi, Kristin Ming, Dominique Legnitto, Torsten B Neilands, Monica Gandhi, Mallory O Johnson
Background: There is currently no gold standard for assessing antiretroviral (ARV) adherence, so researchers often resort to the most feasible and cost-effective methods possible (eg, self-report), which may be biased or inaccurate. The goal of our study was to evaluate the feasibility and acceptability of innovative and remote methods to estimate ARV adherence, which can potentially be conducted with less time and financial resources in a wide range of clinic and research settings. Here, we describe the research protocol for studying these novel methods and some lessons learned...
2018: Patient Preference and Adherence
Jin Lou, Junjie Huang, Zitong Wang, Bingbing Wen, Chuanqing Tu, Wangxiang Huang, Zhimin Zhai, Xin Du
Background: Treatment-free remission (TFR) is becoming an essential goal for chronic myeloid leukemia (CML) patients in clinical practice. Few studies have emphasized patient attitudes or preferences about discontinuing tyrosine kinase inhibitors treatment. This study aimed to evaluate the characteristics of Chinese CML patients and their views and perspectives on TFR. Methods: A total of 329 CML patients participated in this multicenter, questionnaire-based, standardized, semi-structured, interview-guided, open-ended, cross-sectional study...
2018: Patient Preference and Adherence
Walid K Abdelbasset, Saud F Alsubaie, Sayed A Tantawy, Tamer I Abo Elyazed, Dalia M Kamel
Background: It has been documented that aerobic exercise may increase pulmonary functions and aerobic capacity, but limited data has evaluated a child's satisfaction and pediatric quality of life (PQoL) with exercise training. Objectives: This study aimed to investigate the effects of moderate-intensity exercise training on asthmatic school-aged children. Subjects and methods: This study included 38 school-aged children with asthma (23 males and 15 females) aged between 8-12 years...
2018: Patient Preference and Adherence
Dorcey L Applyrs, Edith M Williams, Trevor D Faith, Diane L Kamen, Elizabeth Vazques, Janine M Jurkowski
Objective: This study investigated the association among corticosteroids, emotional health, physical health, and work/regular activities of daily living in an ethnically diverse sample of women with systemic lupus erythematosus. Methods: A secondary analysis of data from the Medical University of South Carolina Lupus Database was conducted between confirmed cases of lupus (n = 224) and controls (n = 60). The sample comprised 57 Caucasian Americans, 141 Gullah African Americans (a subpopulation of African Americans from the Sea Islands of South Carolina and Georgia), and 86 non-Gullah African Americans...
2018: Patient Preference and Adherence
Anna Giardini, Marina Maffoni, Przemyslaw Kardas, Elisio Costa
Worldwide, the population is aging and this trend will increase in the future due to medical, technological and scientific advancements. To take care of the elderly is highly demanding and challenging for the health care system due to their frequent condition of chronicity, multimorbidity and the consequent complex management of polypharmacy. Nonadherence to medications and to medical plans is a well-recognized public health problem and a very urgent issue in this population. For this reason, some considerations to identify a new shared approach to integrated care of older people are described...
2018: Patient Preference and Adherence
Antonio Molino, Giovanna Calabrese, Mauro Maniscalco
The pharmacological treatment for stable COPD is based on the use of inhaled bronchodilators (long-acting muscarinic receptor antagonists and long-acting beta-2 adrenoceptor agonists) and inhaled corticosteroids. The use of triple inhaled therapy is recommended to selected patients with COPD. Among the various inhaler combinations in triple therapy, a new combination by fluticasone furoate, umeclidinium, and vilanterol is available for COPD patients. Recently, a large clinical trial using this combination has been published, resulting in a reduction in exacerbation rate in COPD patients...
2018: Patient Preference and Adherence
Dan V Blalock, Patrick E McKnight, Todd B Kashdan, Simone C Franz
Objective: The present study examined the proposition that patients need to focus on something beyond simply "getting better". In a sample of arthritis sufferers, we distinguished individuals by the goals that motivated them - moving toward aspirational goals and maximizing gains (promotion focus) rather than obligations and minimizing losses (prevention focus) - and how these motivational styles influenced treatment. Methods: Patients (N=254) participated in a randomized controlled trial of resistance training and self-management, providing 6 time points of data over 2 years...
2018: Patient Preference and Adherence
Louis S Matza, Kristina S Boye, Jessica B Jordan, Kirsi Norrbacka, Raffaella Gentilella, Amara R Tiebout, Chantelle Browne, Marco Orsini Federici, Giovanni Biricolti, Katie D Stewart
Objectives: Several glucagon-like peptide-1 receptor agonists are administered as weekly injections for treatment of type 2 diabetes (T2D). These medications vary in their injection processes, and a recent study in the UK found that these differences had an impact on patient preference and health state utilities. The purpose of this study was to replicate the UK study in Italy to examine preferences of an Italian patient sample, while allowing for comparison between utilities in the UK and Italy...
2018: Patient Preference and Adherence
Zeleke Bonger, Solomon Shiferaw, Eshetu Zerihun Tariku
Background: Self-care practices in diabetes patients are crucial to keep the illness under control and prevent complications. Effective management of diabetes will be a difficult task without adequate understanding of the existing level of practice related to diabetes self-care. This study is, therefore, aimed at assessing the self-care practice and its associated factors among patients with type 2 diabetes in Tikur Anbessa Specialized Hospital, Ethiopia. Materials and methods: A health facility-based cross-sectional study was conducted among 419 type 2 diabetes patients from March 29, 2013, to May 16, 2013...
2018: Patient Preference and Adherence
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