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International Journal of Rheumatic Diseases

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https://www.readbyqxmd.com/read/28425192/soluble-hla-e-a-follow-up-biomarker-in-takayasu-arteritis-independent-of-hla-e-genotype
#1
Ruchika Goel, Jayakanthan Kabeerdoss, Hindhumathi Mohan, Sumita Danda, Visali Jayaseelan, T Sathish Kumar, John Jude, Paul Bacon, George Joseph, Debashish Danda
AIM: Disease activity assessment in Takayasu arteritis (TA) is challenging. Human leukocyte antigen E (HLA-E) is shed from endothelium into serum as a soluble molecule (sHLA-E) in response to inflammation. We aimed to study: (i) utility of sHLA-E as a biomarker of disease activity; and (ii) association of HLA-E polymorphism rs1264457 with clinical disease in Asian-Indian TA patients. MATERIALS AND METHODS: In phase-1, sHLA-E levels were estimated in sera of 50 consecutive TA patients at baseline visit and 27 healthy controls...
April 19, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28425178/sleep-quality-clinical-and-psychological-manifestations-in-women-with-systemic-lupus-erythematosus
#2
Virginia Moraleda, Germán Prados, María P Martínez, Ana I Sánchez, José M Sabio, Elena Miró
AIM: Sleep problems are a common complaint in systemic lupus erythematosus (SLE) patients. We analyzed sleep quality with subjective and objective measures in a sample with SLE and its possible relationships with the main manifestations of the disease. METHODS: Twenty-one women with SLE and 20 healthy women participated in the study. All participants were evaluated with actigraphy for a week and they completed self-report instruments of sleep quality, quality of life, fatigue, anxiety, depression and perceived stress...
April 19, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28419763/the-effects-of-local-cold-application-on-fibromyalgia-pain
#3
Naside Yilmaz, Emine Kiyak
AIM: This study was conducted to evaluate the effects of local cold application on pain when applied to the trapezius muscles of patients with fibromyalgia. METHOD: A one-group, pre-test/post-test, pre-experimental model was applied in this study, which was conducted with 55 fibromyalgia patients who presented to a rheumatology outpatient clinic. A 10-min cold application was administered to one trapezius muscle of each patient. The participants' pain was evaluated, in total, four times (before the cold application and 10 min, 1...
April 17, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28419761/pyoderma-gangrenosum-in-sj%C3%A3-gren-s-syndrome-and-its-successful-treatment-with-topical-application-of-etanercept
#4
LETTER
Vikram Haridas, Praveenkumar Shetty, Leonard C Dsouza, U S Dinesh, Kiran Haridas, Anil Bargale
No abstract text is available yet for this article.
April 17, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28397343/celiac-disease-prevalence-in-a-large-series-of-patients-with-behcet-s-disease
#5
Erdem Koçak, Erdem Akbal, Yavuz Beyazit, Bilal Ergül, Arzu Karataş, Seyfettin Köklü, H Meral Ekşioğlu
AIM: There are common findings between Behçet's disease (BD) and celiac disease (CD) based on similar immunological pathogenesis and there is only limited data available investigating the link between these two diseases. Furthermore, documented gastrointestinal (GI) involvement with marked upper GI symptoms in BD has been rarely reported. The aim of this study was to assess the prevalence of CD and to evaluate endoscopic findings in Turkish BD patients. METHODS: A total of 210 BD patients were included in the study...
April 11, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28397348/development-of-psoriasis-with-relapse-of-dermatomyositis-associated-interstitial-lung-disease
#6
LETTER
Yasunobu Kato, Toshiyuki Yamamoto
No abstract text is available yet for this article.
April 10, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28378461/increased-serum-interleukin-32-levels-in-patients-with-beh%C3%A3-et-s-disease
#7
You-Jung Ha, Jin-Su Park, Mi-Il Kang, Soo-Kon Lee, Yong-Beom Park, Sang-Won Lee
AIM: Interleukin (IL)-32 is known to act as a proinflammatory cytokine and is likely involved in several chronic inflammatory diseases. The aims of this study were to investigate whether serum IL-32 levels are elevated in patients with Behçet's disease (BD) and to identify the correlation between IL-32 levels and disease activity. METHODS: We enrolled 50 patients with BD and 35 healthy controls. Serum IL-32 levels were measured using an enzyme-linked immunosorbent assay...
April 5, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28378451/association-between-medial-meniscus-extrusion-and-spontaneous-osteonecrosis-of-the-knee
#8
Tadashi Yasuda, Satoshi Ota, Satoshi Fujita, Eijiro Onishi, Koichi Iwaki, Hiroshi Yamamoto
AIM: Medial meniscus tear has been proposed as a potential etiology of spontaneous osteonecrosis of the knee (SONK). Disruption of collagen fibers within the meniscus causes meniscal extrusion, which results in alteration in load distribution in the knee. Our purpose was to determine whether the extent of medial meniscus extrusion correlates with the severity of SONK in the medial femoral condyle. METHODS: Radiological stage of SONK and femorotibial angle (FTA) were determined on knee radiographs...
April 5, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28378434/presentation-of-missed-childhood-kawasaki-disease-in-adults-experience-from-a-tertiary-care-center-in-north-india
#9
Rajesh Vijayvergiya, Sagar Bhattad, Subhash Varma, Manphool Singhal, John Gordon, Surjit Singh
AIM: Kawasaki disease (KD) is the most common cause of acquired heart disease in children in Japan, North America and Europe. Undiagnosed and untreated KD can have clinically significant consequences later in life. The clinical spectrum of missed childhood KD is frequently being recognized during adulthood. We report four adult cases of acute coronary events, in which coronary angiography was suggestive of sequelae of KD. METHODS: Four adults who presented with acute coronary events, had coronary angiography for evaluation...
April 5, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28378420/cholesterol-metabolism-in-pathogenesis-of-osteoarthritis-disease
#10
REVIEW
Saba Farnaghi, Ross Crawford, Yin Xiao, Indira Prasadam
Several lines of research indicate that osteoarthritis (OA) is not only a joint disorder associated with mechanical stress and aging but also a 'metabolic syndrome' in which several risk factors work together to contribute to disease initiation and/or development. One such metabolic risk factor could be high cholesterol levels in the body. Even though high cholesterol level is a well-known risk factor for cardiovascular disorders, its possible role in musculoskeletal diseases, particularly OA, is not clear...
April 5, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28378406/fludarabine-is-effective-in-treating-refractory-hemophagocytic-lymphohistiocytosis-with-brucellosis
#11
LETTER
Jian Gang Jin
No abstract text is available yet for this article.
April 5, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28378356/effect-of-an-orally-formulated-processed-black-cumin-from-iranian-traditional-medicine-pharmacopoeia-in-relieving-symptoms-of-knee-osteoarthritis-a-prospective-randomized-double-blind-and-placebo-controlled-clinical-trial
#12
Ahmad Salimzadeh, Anahita Ghourchian, Rasool Choopani, Homa Hajimehdipoor, Mohammad Kamalinejad, Maryam Abolhasani
AIM: Osteoarthritis is a global health problem, especially for the elderly. A good replacement for non-surgical treatments is the use of traditional medicines. We selected a revere plant (Nigella sativa L.), a widely utilized medicinal herb for the treatment of inflammatory conditions, from the Iranian traditional medicine (ITM) pharmacopoeia with proven anti-inflammatory and analgesic actions. METHODS: We performed a prospective, randomized, double-blind, and placebo-controlled clinical trial, in order to investigate whether the herb is useful in alleviating the symptoms of knee osteoarthritis...
April 5, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28374575/comparison-of-heart-rate-variability-and-classic-autonomic-testing-for-detection-of-cardiac-autonomic-dysfunction-in-patients-with-fibromyalgia
#13
EDITORIAL
Ersel Onrat, Onder Akci
No abstract text is available yet for this article.
April 4, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28337860/clinical-features-and-long-term-outcomes-of-105-granulomatosis-with-polyangiitis-patients-a-single-center-experience-from-north-india
#14
Aman Sharma, Godasi S R S N K Naidu, Manish Rathi, Roshan Verma, Manish Modi, Benzeeta Pinto, Kusum Sharma, Varun Dhir, Manphool Singhal, Mahesh Prakash, Ritambhra Nada, Naresh K Panda, Ranjana W Minz
AIM: To describe the clinical features, treatment and long-term outcomes in north Indian patients with granulomatosis with polyangiitis (GPA). METHODS: Clinical details, Birmingham Vasculitis Activity Score (BVAS-v3), laboratory data, histopathology findings, treatment details and outcomes of all consecutive patients diagnosed as having GPA between April 2005 and April 2016 were retrieved. European Vasculitis Study Group definitions were used to classify patients into localized, early systemic, generalized, severe and refractory categories...
March 24, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28337853/long-term-efficacy-and-tolerability-of-mycophenolate-mofetil-therapy-in-diffuse-scleroderma-skin-disease
#15
Daniel Boulos, Gene-Siew Ngian, Anton Rajadurai, Kathleen Elford, Wendy Stevens, Susanna Proudman, Claire Owen, Janet Roddy, Mandana Nikpour, Peter Youssef, Catherine Hill, Joanne Sahhar
OBJECTIVES: To assess the long-term efficacy and tolerability of mycophenolate mofetil (MMF) in patients with diffuse cutaneous systemic sclerosis (dcSSc). METHODS: Patients enrolled in the Australian Scleroderma Cohort study with dcSSc and baseline modified Rodnan skin score (mRSS) ≥ 12 who were treated for a minimum of 12 months with MMF for the primary indication of skin disease were included and their prospectively collected data retrieved. Change in mRSS, the proportion with a clinically significant improvement (reduction in mRSS ≥ 5 from baseline) and adverse effects due to therapy were determined...
March 24, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28337851/low-prevalence-of-knee-chondrocalcinosis-and-its-catabolic-association-by-use-of-serum-matrix-metalloproteinase-3-a-rural-japanese-population-study
#16
Daisuke Chiba, Eiichi Tsuda, Eiji Sasaki, Ippei Takahashi, Shigeyuki Nakaji, Yasuyuki Ishibashi
AIM: This study aimed to elucidate the prevalence of radiographic knee chondrocalcinosis (CC) and to clarify whether CC is correlated with self-reported knee symptoms and a serum catabolic biomarker. METHODS: A total of 1278 volunteers participated. Plain radiographs of both knees were obtained. Identification of a linear calcification in the knee joint space was defined as CC. Patients with a Kellgren-Lawrence grade of 2 or more were considered to have knee osteoarthritis (OA)...
March 24, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28332780/differentiation-of-patented-crystalline-glucosamine-sulfate-from-other-glucosamine-preparations-will-optimize-osteoarthritis-treatment
#17
REVIEW
Sukit Saengnipanthkul, Saranatra Waikakul, Sattaya Rojanasthien, Kitti Totemchokchyakarn, Attarit Srinkapaibulaya, Tai Cheh Chin, Nguyen Mai Hong, Olivier Bruyère, Cyrus Cooper, Jean-Yves Reginster, Myat Lwin
Symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) are recommended for the medium- to long-term management of knee osteoarthritis (OA) due to their abilities to control pain, improve function and delay joint structural changes. Among SYSADOAs, evidence is greatest for the patented crystalline glucosamine sulfate (pCGS) formulation (Mylan). Glucosamine is widely available as glucosamine sulfate (GS) and glucosamine hydrochloride (GH) preparations that vary substantially in molecular form, pharmaceutical formulation and dose regimen...
March 23, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28328178/clinical-characteristics-of-multifocal-osteonecrosis-in-korean-patients-with-rheumatic-disease
#18
Hye-Jin Jeong, Dam Kim, Soo-Kyung Cho, Yeesuk Kim, Sang-Cheol Bae, Yoon-Kyoung Sung
AIM: Osteonecrosis (ON), also known as avascular necrosis, is an important cause of physical disability in rheumatic disease. When this condition affects multiple structures, disability is increased. The purpose of this study was to describe the clinical characteristics of Korean patients with multifocal ON associated with rheumatic disease and to compare them with those of previously reported cases. METHODS: We reviewed the clinical characteristics of eight Korean patients with multifocal ON, defined by the involvement of three or more anatomic sites, associated with rheumatic disease in a single referral academic hospital, and compared them with those of 19 similar cases previously reported in the literature...
March 22, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28328159/improved-disease-activity-with-fosdagrocorat-pf-04171327-a-partial-agonist-of-the-glucocorticoid-receptor-in-patients-with-rheumatoid-arthritis-a-phase-2-randomized-study
#19
Thomas Stock, Dona Fleishaker, Xin Wang, Arnab Mukherjee, Charles Mebus
AIM: To assess efficacy and safety of fosdagrocorat (PF-04171327), a potential dissociated agonist of the glucocorticoid receptor, in rheumatoid arthritis (RA) patients. METHODS: This multicenter, double-blind, parallel-group, active- and placebo-controlled Phase 2 study (NCT00938587) randomized 86 patients (1 : 1 : 1 : 1) to receive fosdagrocorat 10 mg, fosdagrocorat 25 mg, prednisone 5 mg or placebo, all with stable background methotrexate therapy. The primary outcome was change from baseline in Disease Activity Score of 28 joints (DAS28-4[C-reactive protein (CRP)]) after 2 weeks of treatment...
March 22, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28328098/plasma-exchange-successfully-treated-macrophage-activation-syndrome-in-rheumatoid-factor-positive-polyarticular-juvenile-idiopathic-arthritis-with-combined-pneumonia
#20
Lianjie Shi, Fanlei Hu, Chuanhui Xu, Huaqun Zhu, Di Qie, Chuanjie Yuan, Yuhong Tao, Hanmin Liu
Macrophage activation syndrome (MAS) is one of the serious complications associated with rheumatic diseases, especially systemic juvenile idiopathic arthritis (sJIA). Here we describe a 9-year-old girl with rheumatoid factor (RF)-positive polyarticular JIA, not sJIA, combined with pneumonia who was successfully treated by plasma exchange. She was diagnosed with RF-positive polyarticular JIA based on positive RF and multiple joint swelling and tenderness 3 years ago. She was admitted in our hospital with myalgia for 2 days and a high fever for half a day...
March 22, 2017: International Journal of Rheumatic Diseases
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