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International Journal of Rheumatic Diseases

Kenya Nishioka, Toyoyoshi Uchida, Chie Usui, Ryota Tanaka, Takashi Matsushima, Yoshifuji Matsumoto, Ikuro Nakamura, Kusuki Nishioka, Nobutaka Hattori
AIM: Fibromyalgia syndrome (FMS) is defined as chronic widespread pain that cannot be accounted for by any other medical disorder. Our aim was to explore the prevalence of thyroid autoimmunity in patients with FMS. METHODS: For determining thyroid function in 207 FMS patients, we tested for the titers of free tri-iodothyronine, free thyroxine, thyroid-stimulating hormone (TSH), anti-thyroid peroxidase antibody (TPOAb), anti-thyroglobulin antibody (TgAb) and anti-TSH receptor antibody (TRAb)...
November 30, 2016: International Journal of Rheumatic Diseases
Hee Jung Ryu, Mi Ryoung Seo, Hyo Jin Choi, Kwang-Pil Ko, Pil Whan Park, Han Joo Baek
AIM: The aim of this study was to investigate the association between mean platelet volume (MPV) and clinical manifestations, disease activity or infection in patients with Behçet's disease (BD). METHODS: In total, 193 patients diagnosed with BD according to the international criteria for BD were enrolled. Demographic data, clinical manifestations and laboratory results were collected by medical interviews and reviewing medical records. RESULTS: The female : male ratio was 2 : 1 and the age of symptom onset was 32...
November 25, 2016: International Journal of Rheumatic Diseases
Ankur Kumar, Aman Gupta
No abstract text is available yet for this article.
November 25, 2016: International Journal of Rheumatic Diseases
Yu Heng Kwan, Warren Fong, Nai Lee Lui, Si Ting Yong, Yin Bun Cheung, Rahul Malhotra, Julian Thumboo, Truls Østbye
AIM: The Health Assessment Questionnaire (HAQ) is a popular tool used to measure disability. Few studies have assessed its psychometric properties in patients with spondyloarthritis (SpA). We therefore aimed to assess the reliability and validity of the HAQ in patients with SpA in Singapore. METHOD: Cross-sectional data from a registry of 196 patients with SpA recruited from a dedicated tertiary referral clinic in Singapore from 2011 to 2014 was used. Analyses were guided by the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) framework...
November 14, 2016: International Journal of Rheumatic Diseases
James Cheng-Chung Wei, Wen-Chan Tsai, Gustavo Citera, Sameer Kotak, Lyndon Llamado
AIM: To evaluate etanercept in patients from Latin America, Central/Eastern Europe, and Asia with non-radiographic axial spondyloarthritis (nr-axSpA). METHODS: A subset analysis was performed on nr-axSpA patients from Argentina, Colombia, the Czech Republic, Hungary, Russia and Taiwan who were enrolled in EMBARK (NCT01258738). Patients received either etanercept 50 mg or placebo once weekly. The primary endpoint was proportion of patients achieving 40% improvement from baseline based on Assessment of SpondyloArthritis International Society (ASAS) criteria...
November 11, 2016: International Journal of Rheumatic Diseases
Ramazan Yilmaz, Ali Salli, Havva Turac Cingoz, Sami Kucuksen, Hatice Ugurlu
AIM: The objective of this study is the evaluation of the effect of vitamin D replacement treatment on musculoskeletal symptoms and quality of life in patients with chronic widespread musculoskeletal pain (CWP) including fibromyalgia (FM) and vitamin D deficiency. METHOD: Patients with nonspecific CWP and vitamin D deficiency (25-OH D3 < 25 ng/mL) were included into the study. Replacement treatments of 50 000 IU/week oral vitamin D3 for 3 months were given to the patients...
November 11, 2016: International Journal of Rheumatic Diseases
Siwach Ram Chander, Seshadri Reddy Varikasuvu, Pandey Anil Kumar, Arunakumari Rupanagudi
No abstract text is available yet for this article.
November 10, 2016: International Journal of Rheumatic Diseases
Taha Moussa, Venkatraman Bhat, Vishwanatha Kini, Basil M Fathalla
AIM: We aim to report the clinical manifestations, genetic testing results, magnetic resonance imaging (MRI) findings and biologics used in the management of non-bacterial osteomyelitis in our center. METHODS: We conducted a retrospective review of medical records. A previously proposed classification was implemented as follows: chronic recurrent multifocal osteomyelitis (CRMO), chronic non-bacterial osteomyelitis (CNBO) and acute non-bacterial osteomyelitis. RESULTS: Four females and three males with a median age at presentation of 6 years (6 months-14 years) presented with arthralgia (7/7), back pain (4/7), arthritis (4/7) and bone pain (2/7)...
November 9, 2016: International Journal of Rheumatic Diseases
Ved Chaturvedi, Molly Mary Thabah, Vinod Ravindran, Patrick D W Kiely
Arthroscopy is an important diagnostic procedure which can be used in rheumatology practice to provide direct visualization of the joint cavity, permitting macroscopic evaluation of the synovium, sampling for histopathologic and microbiologic examination and the potential therapeutic benefit of lavage. The term 'medical arthroscopy' is used here to refer to arthroscopy performed by rheumatologists for these purposes. This term differentiates arthroscopy performed by orthopedic surgeons for structural interventions such as meniscal debridement and ligament repair...
October 27, 2016: International Journal of Rheumatic Diseases
Pingping Zhang, Qiuxia Li, Jun Qi, Qing Lv, Xuqi Zheng, Xinyu Wu, Jieruo Gu
OBJECTIVES: To investigate whether vitamin D receptor (VDR) gene polymorphisms confer susceptibility to aankylosing spondylitis (AS) and study its polymorphisms in Han Chinese. METHODS: We screened single nucleotide polymorphisms (SNPs) in the VDR region through genome-wide genotyping chips in AS cases and healthy controls, then used the exome sequencing result to analyze all the potential AS-associated SNPs in the VDR gene. RESULTS: Thirty-two SNPs were found in the VDR gene in the genome-wide genotyping chips and the logistic regression result showed no significant difference between AS cases and controls...
October 25, 2016: International Journal of Rheumatic Diseases
Kazuha Kizaki, Fumiharu Yamashita, Tomoya Hayashi, Noboru Funakoshi
AIM: This study was designed to investigate which biological agent, infliximab or tocilizumab, would more intensively keep suppressing oxidative stress among well-controlled patients as C-reactive protein (CRP) levels normalized in rheumatoid arthritis (RA). In addition, it was intended to clarify indicative factors of oxidative stress among well-controlled patients with RA. METHODS: We recruited 61 well-controlled (CRP < 0.3 mg/dL within normal ranges) patients with RA using biological agents (infliximab n = 33; tocilizumab n = 28), active RA patients with CRP > 1...
October 24, 2016: International Journal of Rheumatic Diseases
Latika Gupta, Abhishek Zanwar, Anupam Wakhlu, Vikas Agarwal
No abstract text is available yet for this article.
October 2016: International Journal of Rheumatic Diseases
Mehmet Engin Tezcan, Emine Belgin Kocer, Seminur Haznedaroglu, Cemile Sonmez, Ridvan Mercan, Aysegul Atak Yucel, Ceyla Irkec, Berivan Bitik, Berna Goker
AIM: Cognitive dysfunction is a neurologic manifestation in primary Sjögren syndrome (PSS). On the other hand, several antibodies are related to cognitive dysfunction. The aim of this study is to assess the cognitive dysfunction of PSS patients via detailed neurologic tests. Moreover, its associations with antibodies were also evaluated. METHOD: Twenty-eight female patients with PSS and 17 healthy controls comprised the study groups. Short-term memory, long-term memory, verbal learning, visual memory, visual spatial perception, attention, verbal frequency function, executive functions and information processing speed were evaluated with neurologic tests in both of the study groups...
October 2016: International Journal of Rheumatic Diseases
Aman Sharma, Benzeeta Pinto, Sunil Dogra, Kusum Sharma, Palvi Goyal, Vinay Sagar, Varun Dhir, Shefali Sharma, Surjit Singh
AIM: Poncet's disease is a well recognized form of reactive arthritis in the presence of extra-articular tuberculosis. There are very limited case reports even from countries where tuberculosis is common and there are no accepted diagnostic criteria for Poncet's disease. In the present study we are describing clinical features of Poncet's disease from a tuberculosis-endemic region along with a proposal of a new diagnostic criteria. METHODS: All patients diagnosed as having Poncet's disease were included...
October 2016: International Journal of Rheumatic Diseases
Sanchit Sharma, Uma Kumar
No abstract text is available yet for this article.
September 2016: International Journal of Rheumatic Diseases
(no author information available yet)
No abstract text is available yet for this article.
September 2016: International Journal of Rheumatic Diseases
Anand N Malaviya
This review highlights the story of how methotrexate (MTX), a drug discovered for the treatment of childhood leukemia, became the mainstay of treatment and the standard-of-care for rheumatoid arthritis (RA) and was also found useful for several additional related rheumatological diseases. As against several synthetic disease-modifying antirheumatic drugs (csDMARDs) for treating RA that were discovered serendipitously, the use of low-dose MTX (LD-MTX) was based on sound reasoning and astute observations made in the 1940s and 1950s...
September 2016: International Journal of Rheumatic Diseases
Abbas Arj, Mohsen Razavi Zade, Maryam Yavari, Hossein Akbari, Batol Zamani, Zatollah Asemi
OBJECTIVE: Limited data are available reporting the effect of proton pump inhibitor (PPI) use on changes in bone mineral density (BMD). The aim of this study was to investigate the relationship between PPI use and BMD. METHODS: The current cross-sectional study included 80 patients (31 male and 49 female) aged 20-45 years old without history of hip fracture with a follow-up of at least 2 years. The study was carried out in 40 daily PPI users and 40 PPI non-users...
September 2016: International Journal of Rheumatic Diseases
Batol Zamani, Hamid R Golkar, Shima Farshbaf, Modjtaba Emadi-Baygi, Maryam Tajabadi-Ebrahimi, Parvaneh Jafari, Reyhaneh Akhavan, Mohsen Taghizadeh, Mohammad R Memarzadeh, Zatollah Asemi
OBJECTIVE: This study was performed to determine the effects of probiotic supplementation on clinical and metabolic status of patients with rheumatoid arthritis (RA). METHODS: Sixty patients with RA aged 25-70 years were assigned into two groups to receive either probiotic capsules (n = 30) or placebo (n = 30) in this randomized, double-blind, placebo-controlled trial. The patients in the probiotic group received a daily capsule that contained three viable and freeze-dried strains: Lactobacillus acidophilus (2 × 10(9) colony-forming units [CFU]/g), Lactobacillus casei (2 × 10(9) CFU/g) and Bifidobacterium bifidum (2 × 10(9) CFU/g) for 8 weeks...
September 2016: International Journal of Rheumatic Diseases
Chingching Foocharoen, Sittichai Netwijitpan, Ajanee Mahakkanukrauh, Siraphop Suwannaroj, Ratanavadee Nanagara
BACKGROUND: Scleroderma with characteristics of other connective tissue diseases is called scleroderma overlap syndrome (SOV); the clinical features of which have yet to be investigated among Thai patients. OBJECTIVE: To determine the clinical differences between pure scleroderma and SOV. METHODS: A historical cohort study was conducted among patients with pure scleroderma versus those with SOV. Subjects were over 18 years of age and followed up at Srinagarind Hospital, Khon Kaen University, Thailand, between January 2006 and December 2011...
September 2016: International Journal of Rheumatic Diseases
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