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Circulation. Arrhythmia and Electrophysiology

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https://www.readbyqxmd.com/read/29330333/standard-ablation-versus-magnetic-resonance-imaging-guided-ablation-in-the-treatment-of-ventricular-tachycardia
#1
LETTER
Tarek Zghaib, Esra G Ipek, Rozann Hansford, Hiroshi Ashikaga, Ronald D Berger, Joseph E Marine, David D Spragg, Harikrishna Tandri, Stefan L Zimmerman, Henry Halperin, Scott Brancato, Hugh Calkins, Charles Henrikson, Saman Nazarian
No abstract text is available yet for this article.
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29330332/identification-and-characterization-of-sites-where-persistent-atrial-fibrillation-is-terminated-by-localized-ablation
#2
Junaid A B Zaman, William H Sauer, Mahmood I Alhusseini, Tina Baykaner, Ryan T Borne, Christopher A B Kowalewski, Sonia Busch, Paul C Zei, Shirley Park, Mohan N Viswanathan, Paul J Wang, Johannes Brachmann, David E Krummen, John M Miller, Wouter Jan Rappel, Sanjiv M Narayan, Nicholas S Peters
BACKGROUND: The mechanisms by which persistent atrial fibrillation (AF) terminates via localized ablation are not well understood. To address the hypothesis that sites where localized ablation terminates persistent AF have characteristics identifiable with activation mapping during AF, we systematically examined activation patterns acquired only in cases of unequivocal termination by ablation. METHODS AND RESULTS: We recruited 57 patients with persistent AF undergoing ablation, in whom localized ablation terminated AF to sinus rhythm or organized tachycardia...
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29326132/ventricular-arrhythmias-linked-to-the-left-ventricular-summit-communicating-veins-a-new-mapping-approach-for-an-old-ablation-problem
#3
EDITORIAL
Daniele Muser, Pasquale Santangeli
No abstract text is available yet for this article.
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29326131/computer-modeling-the-future-of-cardiac-resynchronization-therapy-patient-selection
#4
EDITORIAL
Daniel B Cobb, Michael R Gold
No abstract text is available yet for this article.
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29326130/inward-rectifier-potassium-channels-kir2-x-and-caveolin-3-domain-specific-interaction-implications-for-purkinje-cell-dependent-ventricular-arrhythmias
#5
Ravi Vaidyanathan, Hanora Van Ert, Kazi T Haq, Stefano Morotti, Samuel Esch, Elise C McCune, Eleonora Grandi, Lee L Eckhardt
BACKGROUND: In human cardiac ventricle, IK1 is mainly comprised Kir2.1, but Kir2.2 and Kir2.3 heterotetramers occur and modulate IK1. Long-QT syndrome-9-associated CAV3 mutations cause decreased Kir2.1 current density, but Kir2.x heterotetramers have not been studied. Here, we determine the effect of long-QT syndrome-9-CAV3 mutation F97C on Kir2.x homo- and heterotetramers and model-associated arrhythmia mechanisms. METHODS AND RESULTS: Super-resolution microscopy, co-immunoprecipitation, cellular electrophysiology, on-cell Western blotting, and simulation of Purkinje and ventricular myocyte mathematical models were used...
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29326129/machine-learning-algorithm-predicts-cardiac-resynchronization-therapy-outcomes-lessons-from-the-companion-trial
#6
Matthew M Kalscheur, Ryan T Kipp, Matthew C Tattersall, Chaoqun Mei, Kevin A Buhr, David L DeMets, Michael E Field, Lee L Eckhardt, C David Page
BACKGROUND: Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in heart failure patients with reduced left ventricular function and intraventricular conduction delay. However, individual outcomes vary significantly. This study sought to use a machine learning algorithm to develop a model to predict outcomes after CRT. METHODS AND RESULTS: Models were developed with machine learning algorithms to predict all-cause mortality or heart failure hospitalization at 12 months post-CRT in the COMPANION trial (Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure)...
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29326128/idiopathic-ventricular-arrhythmias-originating-from-the-vicinity-of-the-communicating-vein-of-cardiac-venous-systems-at-the-left-ventricular-summit
#7
Yuki Komatsu, Akihiko Nogami, Yasutoshi Shinoda, Keita Masuda, Takeshi Machino, Kenji Kuroki, Hiro Yamasaki, Yukio Sekiguchi, Kazutaka Aonuma
BACKGROUND: The communicating vein (CV) between the great cardiac vein and small cardiac venous systems passes between the aortic and pulmonary annulus and is located in close association with the left ventricular summit (summit CV). METHODS AND RESULTS: Thirty-one patients with idiopathic ventricular arrhythmias (VAs) underwent mapping of the left ventricular summit by using a 2F microcatheter introduced into the summit CV with coronary sinus venographic guidance...
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29321193/cardiac-implantable-electronic-device-infections-and-lead-extraction-are-patients-with-renal-insufficiency-special
#8
EDITORIAL
Jonathan Chrispin, Charles J Love
No abstract text is available yet for this article.
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29321192/transvenous-lead-extraction-in-chronic-kidney-disease-and-dialysis-patients-with-infected-cardiac-devices
#9
Amr F Barakat, Oussama M Wazni, Khaldoun G Tarakji, Thomas Callahan, Nayef Nimri, Walid I Saliba, Shailee Shah, Karim Abdur Rehman, John Rickard, Michael P Brunner, David O Martin, Mohamed Kanj, Bryan Baranowski, Daniel Cantillon, Mark Niebauer, Thomas Dresing, Bruce D Lindsay, Bruce L Wilkoff, Ayman A Hussein
BACKGROUND: Cardiac implantable electronic device infections have been on the rise. A high-risk population is that with renal disease, especially dialysis. We aimed to assess procedural profiles and clinical outcomes of transvenous lead extraction for cardiac implantable electronic device infection based on renal disease status. METHODS AND RESULTS: In 1420 consecutive patients undergoing transvenous lead extraction of infected cardiac implantable electronic devices (1996-2012), we assessed procedural profiles and clinical outcomes in 3 groups: normal renal function (group 1, n=1159), renal dysfunction not requiring dialysis (group 2, n=163), and dialysis (group 3, n=98)...
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29321191/mortality-after-magnetic-resonance-imaging-of-the-brain-in-patients-with-cardiovascular-implantable-devices
#10
Deepak Padmanabhan, Mary L Jondal, David O Hodge, Ramila A Mehta, Nancy G Acker, Connie M Dalzell, Suraj Kapa, Samuel J Asirvatham, Yong-Mei Cha, Joel P Felmlee, Robert E Watson, Paul A Friedman
BACKGROUND: Use of magnetic resonance imaging (MRI) brain is restricted in patients with cardiovascular implantable electronic devices (CIEDs). We proposed to determine whether mortality difference exists for patients with non-MRI-conditional CIEDs undergoing brain MRI compared with controls. METHODS AND RESULTS: Retrospective analysis of prospectively collected data was performed to compare all-cause mortality in patients with CIEDs undergoing brain MRI (CIED-MRI) with 3 control groups matched for age, sex, imaging year, and type of CIED: (1) no CIED, brain MRI (no-CIED-MRI); (2) CIED, brain computerized tomography (CT) scan (CIED-CT); and (3) no CIED, brain CT (no-CIED-CT)...
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29311163/january-8th-question
#11
Amit Noheria
No abstract text is available yet for this article.
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29311162/differential-expression-and-remodeling-of-transient-outward-potassium-currents-in-human-left-ventricles
#12
Eric K Johnson, Steven J Springer, Wei Wang, Edward J Dranoff, Yan Zhang, Evelyn M Kanter, Kathryn A Yamada, Jeanne M Nerbonne
BACKGROUND: Myocardial, transient, outward currents, Ito, have been shown to play pivotal roles in action potential (AP) repolarization and remodeling in animal models. The properties and contribution of Ito to left ventricular (LV) repolarization in the human heart, however, are poorly defined. METHODS AND RESULTS: Whole-cell, voltage-clamp recordings, acquired at physiological (35°C to 37°C) temperatures, from myocytes isolated from the LV of nonfailing human hearts identified 2 distinct transient currents, Ito,fast (Ito,f) and Ito,slow (Ito,s), with significantly (P<0...
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29305400/effect-of-baseline-antiarrhythmic-drug-on-outcomes-with-ablation-in-ischemic-ventricular-tachycardia-a-vanish-substudy-ventricular-tachycardia-ablation-versus-escalated-antiarrhythmic-drug-therapy-in-ischemic-heart-disease
#13
Ratika Parkash, Isabelle Nault, Lena Rivard, Lorne Gula, Vidal Essebag, Pablo Nery, Stanley Tung, Jean-Marc Raymond, Laurence Sterns, Steve Doucette, George Wells, Anthony S L Tang, William G Stevenson, John L Sapp
BACKGROUND: The VANISH trial (Ventricular Tachycardia Ablation Versus Escalated Antiarrhythmic Drug Therapy in Ischemic Heart Disease) compared the effectiveness of escalated antiarrhythmic drug therapy to catheter ablation in patients with prior myocardial infarction, an implanted defibrillator, and ventricular tachycardia (VT). The effectiveness of these interventions in patients on sotalol versus amiodarone was compared. METHODS AND RESULTS: Analysis was conducted based on whether patients had recurrent VT, despite amiodarone (amio-refractory) or nonamiodarone drugs (sotalol-refractory)...
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29269560/quantification-of-the-arrhythmogenic-effects-of-spontaneous-atrial-extrasystole-using-high-resolution-epicardial-mapping
#14
Christophe P Teuwen, Charles Kik, Lisette J M E van der Does, Eva A H Lanters, Paul Knops, Elisabeth M J P Mouws, Ad J J C Bogers, Natasja M S de Groot
BACKGROUND: Atrial extrasystoles (AES) can initiate atrial fibrillation. However, the impact of spontaneous AES on intra-atrial conduction is unknown. The aims of this study were to examine conduction disorders provoked by AES and to correlate these conduction differences with patient characteristics, mapping locations, and type of AES. METHODS AND RESULTS: High-resolution epicardial mapping (electrodes N=128 or N=192; interelectrode distance, 2 mm) of the entire atrial surface was performed in patients (N=164; 69...
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29258996/in-this-issue-december
#15
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
December 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29254949/rotational-drivers-in-atrial-fibrillation-are-multiple-techniques-circling-similar-mechanisms
#16
EDITORIAL
Junaid A B Zaman, Albert J Rogers, Sanjiv M Narayan
No abstract text is available yet for this article.
December 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29254948/ventricular-tachycardia-ablation-are-we-in-a-new-age
#17
EDITORIAL
Arvindh N Kanagasundram, Ricardo M Lugo, Gregory F Michaud
No abstract text is available yet for this article.
December 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29254947/ablation-of-rotor-domains-effectively-modulates-dynamics-of-human-long-standing-persistent-atrial-fibrillation
#18
David Calvo, José Rubín, Diego Pérez, César Morís
BACKGROUND: In human long-standing persistent atrial fibrillation, rotors potentially explain atrial fibrillation maintenance, but their ablation remains controversial. We aimed to explore original phase/frequency mapping methods to locate rotors and track changes induced by their ablation. METHODS AND RESULTS: Thirteen patients with long-standing persistent atrial fibrillation (duration, 12-72 months) underwent phase/frequency mapping (Hilbert/Fourier transforms; CARTO-Finder) of the left and right atria (PentaRay catheter)...
December 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29254946/ventricular-tachycardia-ablation-in-the-elderly-an-international-ventricular-tachycardia-center-collaborative-group-analysis
#19
MULTICENTER STUDY
Kairav Vakil, Santiago Garcia, Roderick Tung, Marmar Vaseghi, Usha Tedrow, Paolo Della Bella, David S Frankel, Pasquale Vergara, Luigi Di Biase, Koichi Nagashima, Shiro Nakahara, Wendy S Tzou, J David Burkhardt, Timm Dickfeld, J Peter Weiss, Jared Bunch, David Callans, Dhanunjaya Lakkireddy, Andrea Natale, William H Sauer, William G Stevenson, Francis Marchlinski, Kalyanam Shivkumar, Venkatakrishna N Tholakanahalli
BACKGROUND: Successful ventricular tachycardia (VT) ablation is associated with improved survival in patients with heart failure. However, the safety and efficacy of VT ablation in the elderly, a population with higher competing nonsudden death risk and comorbidities, have not been well defined. METHODS AND RESULTS: The International Ventricular Tachycardia Center Collaborative Study Group registry of 2061 patients who underwent VT ablation at 12 international centers was analyzed...
December 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29254945/age-of-first-arrhythmic-event-in-brugada-syndrome-data-from-the-sabrus-survey-on-arrhythmic-events-in-brugada-syndrome-in-678-patients
#20
MULTICENTER STUDY
Anat Milman, Antoine Andorin, Jean-Baptiste Gourraud, Frederic Sacher, Philippe Mabo, Sung-Hwan Kim, Shingo Maeda, Yoshihide Takahashi, Tsukasa Kamakura, Takeshi Aiba, Giulio Conte, Jimmy J M Juang, Eran Leshem, Michael Rahkovich, Aviram Hochstadt, Yuka Mizusawa, Pieter G Postema, Elena Arbelo, Zhengrong Huang, Isabelle Denjoy, Carla Giustetto, Yanushi D Wijeyeratne, Carlo Napolitano, Yoav Michowitz, Ramon Brugada, Ruben Casado-Arroyo, Jean Champagne, Leonardo Calo, Georgia Sarquella-Brugada, Jacob Tfelt-Hansen, Silvia G Priori, Masahiko Takagi, Christian Veltmann, Pietro Delise, Domenico Corrado, Elijah R Behr, Fiorenzo Gaita, Gan-Xin Yan, Josep Brugada, Antoine Leenhardt, Arthur A M Wilde, Pedro Brugada, Kengo F Kusano, Kenzo Hirao, Gi-Byoung Nam, Vincent Probst, Bernard Belhassen
BACKGROUND: Data on the age at first arrhythmic event (AE) in Brugada syndrome are from limited patient cohorts. The aim of this study is 2-fold: (1) to define the age at first AE in a large cohort of patients with Brugada syndrome, and (2) to assess the influence of the mode of AE documentation, sex, and ethnicity on the age at first AE. METHODS AND RESULTS: A survey of 23 centers from 10 Western and 4 Asian countries gathered data from 678 patients with Brugada syndrome (91...
December 2017: Circulation. Arrhythmia and Electrophysiology
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