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Clinical and Experimental Otorhinolaryngology

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https://www.readbyqxmd.com/read/28877566/is-ginger-effective-in-reducing-post-tonsillectomy-morbidity-a-prospective-randomised-clinical-trial
#1
İlker Koçak, Cemil Yücepur, Ozan Gökler
Objectives: An assessment of the effects of ginger on pain, nausea, vomiting, bleeding, and wound site healing that occur after tonsillectomy. Methods: This prospective clinical study was participated by 49 patients aged 18-45 years out of 56 patients that underwent tonsillectomy and regularly attended follow-up visits. The patients were randomly divided into two groups. Group 1 consisted of 23 patients that used ginger capsules and group 2 consisted of 26 patients that did not use ginger capsules in addition to the routine antibiotic and paracetamol treatment following tonsillectomy...
September 8, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28866875/substance-p-and-calcitonin-gene-related-peptide-in-the-glands-of-external-auditory-canal-skin
#2
Yong Joo Yoon, Jin Yoon, Eun Jung Lee, Jong Seung Kim
Objectives.: The earwax (cerumen) that covers external auditory canal (EAC) skin contains a mixture of ceruminous and sebaceous gland substances, such as lipids, peptides, and proteins. The components secreted from the ceruminous gland that is a modified sweat gland form cerumen and contain several antimicrobial factors. Since substance P (SP) and calcitonin gene-related peptide (CGRP), known as a secretagogue, have been found in sweat glands, our purpose was to determine the expression of SP and CGRP in the glands of EAC skin...
September 5, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28838229/expression-of-prostaglandin-e2-receptors-in-acquired-middle-ear-cholesteatoma
#3
Sujie Wang, Li Xie, Yanfei Zhang, Pengfei Xu, Aiguo Liu
Objectives.: To investigate the expression of prostaglandin E2 receptor subtypes, E-prostanoid (EP) 1-4 receptors, in acquired cholesteatoma and its possible role in the pathologic process of this disorder. Methods.: Specimens of human acquired cholesteatoma were obtained from 29 patients and 19 skin biopsies of normal external auditory canal were as controls. The mRNA and protein expression of EP receptors was assessed by quantitative real-time polymerase chain reaction, immunohistochemistry and Western blot...
August 26, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28797141/butterfly-cartilage-tympanoplasty-long-term-results-excellent-treatment-method-in-small-and-medium-sized-perforations
#4
Isa Kaya, Murat Benzer, Mustafa Uslu, Cem Bilgen, Tayfun Kirazli
Objectives: The aim of this study was to evaluate and report the long-term results of the butterfly cartilage tympanoplasty. Short-term and long-term hearing outcomes were compared according to age and perforation location as well. Methods: Ninety-three patients who were diagnosed with noncomplicated chronic otitis media and underwent microscopic transcanal butterfly cartilage tympanoplasty due to anterior, posterior, and central tympanic membrane perforation were included...
August 12, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28758381/the-impact-of-allergic-rhinitis-on-symptom-improvement-in-pediatric-patients-after-adenotonsillectomy
#5
Dong-Jun Lee, Young-Jun Chung, Yeon-Jun Yang, Ji-Hun Mo
Objectives: It is well known that allergic rhinitis (AR) has positive association with adenotonsillectomy. However, the impact of AR on symptom improvement after adenotonsillectomy is not well documented. Hence, we aimed to evaluate the effect of AR on the symptom improvement after adenotonsillectomy between AR and nonallergic patients. Methods: A retrospective analysis was performed on 250 pediatric patients younger than 10 years old who received adenotonsillectomy from June 2009 to June 2014 in a tertiary referral hospital...
August 1, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28669149/current-treatment-options-for-bilateral-vocal-fold-paralysis-a-state-of-the-art-review
#6
REVIEW
Yike Li, Gaelyn Garrett, David Zealear
Vocal fold paralysis (VFP) refers to neurological causes of reduced or absent movement of one or both vocal folds. Bilateral VFP (BVFP) is characterized by inspiratory dyspnea due to narrowing of the airway at the glottic level with both vocal folds assuming a paramedian position. The primary objective of intervention for BVFP is to relieve patients' dyspnea. Common clinical options for management include tracheostomy, arytenoidectomy and cordotomy. Other options that have been used with varying success include reinnervation techniques and botulinum toxin (Botox) injections into the vocal fold adductors...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28449554/a-study-of-single-nucleotide-polymorphisms-of-tumour-necrosis-factor-%C3%AE-1031-and-tumour-necrosis-factor-%C3%AE-252-in-chronic-rhinosinusitis
#7
Khairunnisak Misron, Suzina Sheikh Ab Hamid, Azlina Ahmad, Ramiza Ramza Ramli
OBJECTIVES: This case-controlled study aimed to identify the association of tumor necrosis factor (TNF)α-1031 and TNFβ+ 252 gene polymorphisms between chronic rhinosinusitis (CRS) and healthy controls. Another purpose of this study was to investigate the associations of these gene polymorphisms with factors related to CRS. METHODS: All deoxyribonucleic acid (DNA) samples were genotyped for TNFα-1031 and TNFβ+252 genes by mean of polymerase chain reaction (PCR) and restriction fragment length polymorphisms (RFLP)...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28449553/changes-in-the-reflux-symptom-index-after-multilevel-surgery-for-obstructive-sleep-apnea
#8
Su Jin Kim, Hyo Yeol Kim, Jong In Jeong, Sang Duk Hong, Seung-Kyu Chung, Hun-Jong Dhong
OBJECTIVES: This study evaluated whether the symptoms of laryngopharyngeal reflux (LPR) change after multilevel surgery for obstructive sleep apnea (OSA). METHODS: Patients who underwent multilevel surgery for OSA between April 2009 and September 2014 were enrolled in this study. All patients underwent preoperative polysomnography prior to surgery and were asked to complete the reflux symptom index (RSI) questionnaire before and after surgery. RESULTS: Of 73 enrolled patients, 24 (33%) reported an RSI score >13 and were thus classified as having reflux...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28103655/temporomandibular-joint-disorders-as-a-cause-of-aural-fullness
#9
Yongxin Peng
OBJECTIVES: Temporomandibular joint disorders (TMD) are often associated with aural manifestations. However, it is not clear whether aural fullness could be induced by TMD. The purpose was to investigate the TMD and effectiveness of TMD treatments in patients with mainly or exclusively aural fullness complaint. METHODS: One hundred and twelve patients, who had aural fullness as the main or sole complaint, presented to the Otolaryngology Department, PLA Army General Hospital, Beijing, China, between January 2010 and January 2015...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28073243/cytokeratin-13-cytokeratin-17-and-ki-67-expression-in-human-acquired-cholesteatoma-and-their-correlation-with-its-destructive-capacity
#10
Mahmood A Hamed, Seiichi Nakata, Kazuya Shiogama, Kenji Suzuki, Ramadan H Sayed, Yoichi Nishimura, Noboru Iwata, Kouhei Sakurai, Badawy S Badawy, Ken-Ichi Inada, Hayato Tsuge, Yutaka Tsutsumi
OBJECTIVES: Cholesteatoma is a nonneoplastic destructive lesion of the temporal bone with debated pathogenesis and bone resorptive mechanism. Both molecular and cellular events chiefly master its activity. Continued research is necessary to clarify factors related to its aggressiveness. We aimed to investigate the expression of Ki-67, cytokeratin 13 (CK13) and cytokeratin 17 (CK17) in acquired nonrecurrent human cholesteatoma and correlate them with its bone destructive capacity. METHODS: A prospective quantitative immunohistochemical study was carried out using fresh acquired cholesteatoma tissues (n=19), collected during cholesteatoma surgery...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28002925/association-between-hearing-impairment-and-albuminuria-with-or-without-diabetes-mellitus
#11
Da Jung Jung, Jae Ho Lee, Taehoon Kim, Hak-Geon Kim, Jae Young Lee, Kyu-Yup Lee
OBJECTIVES: Few studies have evaluated the accurate association between hearing loss (HL) and albuminuria in patients with or without diabetes mellitus (DM). The aim of our study was to identify the clinical effects of albuminuria on HL with or without DM. METHODS: This study included 9,762 patients from the Korean National Health and Nutrition Examination Survey between 2011 and 2013. Participants were divided into 4 groups based on DM and urine albumin/creatinine ratio levels: group 1 included participants with neither DM nor albuminuria, group 2 included participants without DM and with albuminuria, group 3 included patients with DM and without albuminuria, and group 4 included patients with both DM and albuminuria...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/27992712/usefulness-of-allerkin-house-dust-mite-extract-for-nasal-provocation-testing
#12
Kyu-Sung Kim, Tae Young Jang, Young Hyo Kim
OBJECTIVES: We evaluated the clinical usefulness of Allerkin (Lofarma) for nasal provocation testing (NPT) in patients with rhinitis symptoms, by examining changes in nasal symptoms and acoustic parameters after exposure to house dust mite (HDM) extract. METHODS: Twenty patients (16 males and 4 females, mean age: 29.6±14.6 years) were enrolled. We performed skin prick test (SPT) before and 15 and 30 minutes after intranasal challenge with Allerkin HDM extract, and we evaluated symptom changes (nasal obstruction, rhinorrhea, sneezing, and itching) using a visual analogue scale...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/27927010/the-phonetic-characteristics-in-patients-of-bilateral-vocal-fold-paralysis-without-tracheotomy
#13
Yong Tae Hong, Min Ju Park, Yu Jeong Shin, Phan Huu Ngoc Minh, Ki Hwan Hong
OBJECTIVES: Patients with bilateral vocal fold paralysis (BVFP) theoretically have difficulty producing voiceless consonants. However, perceptual studies have revealed clear production of voiceless consonants with good articulation scores in nontracheostomized patients. The purpose of this study was to clarify the production of voiceless stops during articulation in patients with BVFP compared to normal speakers. METHODS: The perceptual, acoustic, and aerodynamic characteristics of patients with BVFP and those with normal speech were investigated with special reference to voiceless stop consonants...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/27927009/efficacy-and-safety-of-guardcel-nasal-packing-after-endoscopic-sinus-surgery-a-prospective-single-blind-randomized-controlled-study
#14
Byungjin Kang, Jeong-Rok Kim, Jae-Min Shin, Il-Ho Park, Heung-Man Lee
OBJECTIVES: Nasal packing after endoscopic sinus surgery is frequently used to control postoperative bleeding, enhance the wound healing process, and prevent lateralization of the middle turbinate, which causes insufficient ventilation. Many biodegradable materials have been developed to reduce pain and mucosal damage during packing removal. The purpose of this study was to compare the efficacy of Guardcel (Genewel Co.) middle meatal packing with a traditional nonabsorbable middle meatal packing, Merocel (Medtronic Xomed), on wound healing and patient satisfaction...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/27671716/analysis-of-prognostic-factors-in-malignant-external-otitis
#15
Sang Kuk Lee, Se A Lee, Sang Woo Seon, Jae Hyun Jung, Jong Dae Lee, Jae Young Choi, Bo Gyung Kim
OBJECTIVES: Malignant external otitis (MEO) is a potentially fatal infection of the external auditory canal, temporal bone, and skull base. Despite treatment with modern antibiotics, MEO can lead to skull base osteomyelitis. Until now, there have been few studies on the prognostic factors of MEO. METHODS: We performed a retrospective study to identify prognostic factors of MEO, and a meta-analysis of other articles investigating MEO. On the basis of disease progression the 28 patients in our study were divided into 'controlled' and 'uncontrolled' groups, consisting of 12 and 16 patients, respectively...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/27515510/postoperative-hypoparathyroidism-and-the-viability-of-the-parathyroid-glands-during-thyroidectomy
#16
Yong Bae Ji, Chang Myeon Song, Eui Suk Sung, Jin Hyeok Jeong, Chang Beom Lee, Kyung Tae
OBJECTIVES: To prevent hypoparathyroidism after thyroidectomy, preservation of the parathyroid glands and their vascularity are essential. The aim of this study was to determine the association between postoperative parathyroid function and the viability of the parathyroid glands during thyroidectomy. METHODS: We prospectively analyzed 111 patients who underwent total thyroidectomy and in whom all 4 parathyroid glands were preserved in situ during the operation...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/27459201/pathologic-evaluation-of-routine-nasopharynx-punch-biopsy-in-the-adult-population-is-it-really-necessary
#17
Sami Bercin, Gokhan Yalciner, Togay Muderris, Fatih Gul, H Mervan Deger, Muzaffer Kiris
OBJECTIVES: To retrospectively evaluate the patients who underwent nasopharyngeal biopsy with imaging and biopsy results, who have or don't have symptoms for nasopharyngeal pathology and to determine the ratio of the nasopharyngeal cancer cases and other pathologic conditions. METHODS: In this retrospective study, 983 patients who underwent endoscopic nasopharyngeal biopsy for symptomatic nasopharyngeal lesions were included. All pathological results, benign or malign was recorded and classified due to the patients' presenting symptoms such as symptomatic for nasopharyngeal pathology or asymptomatic...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/27459200/differences-of-the-voice-parameters-between-the-population-of-different-hearing-tresholds-findings-by-using-the-multi-dimensional-voice-program
#18
Ferit Akil, Umur Yollu, Ozcan Ozturk, Murat Yener
OBJECTIVES: To compare voice parameters in subjects with different hearing level. METHODS: The evaluation consisted of Multi-Dimensional Voice Program (MDVP) and electroglottography. Group 1 consisted of normal hearing subjects which is bilateral average hearing better than 25 decibels (dB) whereas group 2 consisted of patients who have bilateral average hearing between the 25 and 60 dB and group 3 consisted of patients who have bilateral average hearing between the 60 and 90 dB...
September 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28602065/corrective-septorhinoplasty-in-acute-nasal-bone-fractures
#19
Jisung Kim, Hahn Jin Jung, Woo Sub Shim
Objectives: Closed reduction is generally recommended for acute nasal bone fractures, and rhinoplasty is considered in cases with an unsatisfactory outcome. However, concomitant rhinoplasty with fracture reduction might achieve better surgical outcomes. This study investigated the surgical techniques and outcomes in patients who underwent rhinoplasty and fracture reduction concomitantly, during the acute stage of nasal bone fracture. Methods: Forty-five patients who underwent concomitant rhinoplasty and fracture reduction were enrolled...
June 13, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28602068/radiographic-changes-of-the-nasal-septal-body-among-patients-with-sinonasal-diseases
#20
January E Gelera, Devendra Ojar, Jae Hyun Lim, Jee Hye Wee, Jeong-Whun Kim, Chae-Seo Rhee
Objectives: This study aims to determine the anatomical changes occurring in the nasal septal body (NSB) among patients with sinonasal disease and compares the measurements obtained from patients without sinonasal disease. Methods: This was a retrospective study involving review of 405 (93 without and 212 with sinonasal disease) plain paranasal sinus computed tomography (PNS CT) on coronal view at a tertiary training hospital, which was done consecutively from January 2014 to December 2015...
June 6, 2017: Clinical and Experimental Otorhinolaryngology
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