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Clinical and Experimental Otorhinolaryngology

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https://www.readbyqxmd.com/read/29779364/swing-door-overlay-tympanoplasty-surgical-technique-and-outcomes
#1
So Young Park, Hyuk Jae Lee, Myung Joo Shim, Dong Kee Kim, Byung Do Suh, Shi Nae Park
Objectives: The classical overlay tympanoplasty is technically difficult with some disadvantages and thus less popular. However, it is particularly useful for large, anterior perforations. In this study, we describe the technique of a modified overlay graft in the tympanoplasty coined as the swing-door overlay tympanoplasty and report its outcomes. Methods: Retrospective review of patients undergoing the swing-door overlay tympanoplasty at a tertiary referral center between 2003 and 2016 was performed...
May 22, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29779363/prognostic-factors-affecting-surgical-outcomes-in-squamous-cell-carcinoma-of-external-auditory-canal
#2
Gi-Sung Nam, In Seok Moon, Ji Hyung Kim, Sung Huhn Kim, Jae Young Choi, Eun Jin Son
Objectives: Carcinomas of the external auditory canal (EAC) are rare, and management remains challenging. Previous studies seeking prognostic factors for EAC cancers included cancers other than carcinomas. In this study, we analyzed the treatment outcomes of, prognostic factors for, and survival rates associated with specifically squamous cell carcinoma (SCC) of the EAC. Methods: A retrospective review of 26 consecutive patients diagnosed with SCCs of the EAC in a 10-year period was performed in terms of clinical presentation, stage, choice of surgical procedure, and adjunct therapy...
May 22, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29774697/effect-of-adenotonsillectomy-on-attention-in-korean-children-with-sleep-disordered-breathing
#3
Min Jae Kim, Sung Hee Bae, Sung Min Lee, Kang Hyun Lee, Dong-Kyu Kim
Objectives.: Pediatric sleep-disordered breathing (SDB) is a common debilitating disorder that can adversely affect the attention and academic performance of school-age children. Unfortunately, only a few studies have examined the effect of SDB treatment on attention in pediatric populations. Therefore, the aim of this study was to prospectively investigate the effect of SDB treatment on attention in children. Methods.: This study consecutively enrolled SDB children with adenotonsillar hypertrophy...
May 18, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29764011/efficacy-and-safety-of-autologous-stromal-vascular-fraction-in-the-treatment-of-empty-nose-syndrome
#4
Do-Youn Kim, Hye Ran Hong, Eun Wook Choi, Sang Won Yoon, Yong Ju Jang
Objectives: Regenerative treatment using stem cells may serve as treatment option for empty nose syndrome (ENS), which is caused by the lack of turbinate tissue and deranged nervous system in the nasal cavity. We aimed to assess the efficacy and safety of the autologous stromal vascular fraction (SVF) in the treatment of ENS. Methods: In this prospective observational clinical study, we enrolled 10 ENS patients who volunteered to undergo treatment of ENS through the injection of autologous SVF...
May 16, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29719951/assessment-of-volatile-sulfur-compounds-in-adult-and-pediatric-chronic-tonsillitis-patients-receiving-tonsillectomy
#5
Kyu Young Choi, Bum Sang Lee, Jin Hwan Kim, Jung Jun Kim, Young Jang, Jong Wook Choi, Dong Jin Lee
Objectives: To study the volatile sulfur compound (VSC) concentration profile in chronic tonsillitis patients before and after tonsillectomy, and to evaluate the difference between adult and pediatric (children and adolescents) patients. Methods: Thirty adult patients (older than 20 years old) and 30 pediatric patients (younger than 20 years old) who were assigned to get tonsillectomy due to chronic tonsillitis were enrolled in this prospective nonrandomized clinical study...
May 4, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29717571/cochlear-damage-caused-by-the-striking-noise-of-titanium-head-golf-driver
#6
Yong-Ho Park, Juyong Chung, Min Young Lee, Doh Young Lee, Young Ho Kim
Objectives: To investigate how mouse cochleae are affected by the striking noise of titanium head golf driver. Methods: Thirty-two BALB/c mice (20-22 g) with normal hearing were used. The impact acoustic stimulus generated by the striking of titanium golf driver head was centered around 4.5 kHz with 120.5 dB sound pressure level. The recorded impact noise was provided to mice in two ways with the same exposure time of 288 seconds: 1,440 repetitions and an impact duration of 0...
May 3, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29649861/a-systematic-review-of-benefit-of-silicone-intubation-in-endoscopic-dacryocystorhinostomy
#7
Min Gyu Kang, Woo Sub Shim, Dong Keun Shin, Joo Yeon Kim, Ji-Eun Lee, Hahn Jin Jung
Objectives: Insertion of a silicone stent during endoscopic dacryocystorhinostomy (DCR) is the most common procedure to prevent rhinostomy closure. It has been claimed that silicone intubation improves the surgical outcomes of endoscopic DCR. However, many reports have documented an equally high success rate for surgery without silicone intubation. Accordingly, we conducted a systematic review and meta-analysis to clarify the outcomes of endoscopic DCR with and without silicone intubation and determine whether silicone intubation is actually beneficial for patients...
April 14, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29642688/samter-s-triad-state-of-the-art
#8
Sung-Dong Kim, Kyu-Sup Cho
Samter's triad (ST) is a well-known disease characterized by the triad of bronchial asthma, nasal polyps, and aspirin intolerance. Over the past few years, a rapid development in the knowledge of the pathogenesis and clinical characteristics of ST has happened. The aim of this paper is to review the recent investigations on the pathophysiological mechanisms and genetic background, diagnosis, and different therapeutic options of ST to advance our understanding of the mechanism and the therapeutic control of ST...
April 13, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29631390/urine-cotinine-should-be-involved-in-initial-evaluation-of-tinnitus-in-adolescents
#9
Doh Young Lee, Young Ho Kim
Objectives: Smoking is associated with hearing loss, while the correlation between tinnitus and smoking is not fully elucidated. This study aimed to evaluate risk factors of tinnitus in adolescents in terms of smoking, and we identified a rectifiable parameter that can be serially monitored. Methods: A cross-sectional study was conducted using data from the Korea National Health and Nutrition Examination Survey, with 2,782 participants aged 12 to 18 years, from 2008 through 2011...
April 10, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29590744/the-clinical-efficacy-of-silicone-stents-for-endoscopic-dacryocystorhinostomy-a-meta-analysis
#10
Do Hyun Kim, Seon Ik Kim, Ho Jun Jin, Subin Kim, Se Hwan Hwang
Objectives: We evaluated the effect of silicone stent use during endoscopic dacryocystorhinostomy on postoperative morbidities in comparison with versus without a silicone stent. Methods: Two authors independently searched six databases (PubMed, Embase, Scopus, the Web of Science, the Cochrane library, and Google Scholar) from inception of article collection to July 2017. The analysis included prospective randomized studies that compared intraoperative silicone stent insertion (silicone group) with no application of a silicone stent (control group), in which the outcomes of interest were success rate (lacrimal passage patent check with syringing, symptom relief, or endoscopic confirmation of fluorescein dye from the opening of Hasner's valve) and morbidities (e...
March 30, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29587474/evaluation-of-the-possible-neurotoxic-effect-of-the-bone-cement-on-the-facial-nerve-an-experimental-study
#11
Numan Kökten, Oğuz Kadir Eğilmez, M Tayyar Kalcıoğlu, Mustafa Baran, A Işın Doğan Ekici
Objectives: To investigate neurotoxic effect of bone cement (BC) on facial nerve by using electrophysiological and histopathological methods. Methods: This study included 20 male albino Wistar rats, divided into four equal groups. Group A was designed as the control group, while group B was sham group. In the group C, BC solution was dropped onto the facial nerve trunks of rats and washed with physiological saline after 5 seconds. In the group D, BC solution was dropped onto the facial nerve trunks of rats and after allowing 5 minutes to dry, wounds were closed...
March 29, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29587475/microbiological-results-from-middle-ear-effusion-in-pediatric-patients-receiving-ventilation-tube-insertion-multicenter-registry-study-on-the-effectiveness-of-ventilation-tube-insertion-in-pediatric-patients-with-chronic-otitis-media-with-effusion-part-i
#12
Myung Hoon Yoo, Yang-Sun Cho, June Choi, Yun Hoon Choung, Jae-Ho Chung, Jong Woo Chung, Gyu Cheol Han, Eun-Ju Jeon, Beom Cho Jun, Dong-Kee Kim, Kyu Sung Kim, Jun Ho Lee, Kyu-Yup Lee, Seung Hwan Lee, In Seok Moon, Hong Ju Park, Shi Nae Park, Jihye Rhee, Jae Hyun Seo, Seung Geun Yeo
Objectives: The aim of this multicenter registry study was to investigate the effectiveness of ventilation tube insertion and the microbiology of otitis media with effusion (OME) in children. This part I study was conducted to evaluate the microbiological profile of children with OME who needed ventilation tube insertion. Methods: Patients <15 years old who were diagnosed as having OME and received ventilation tube insertion were prospectively enrolled in 16 tertiary hospitals from June 2014 to December 2016...
March 28, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29519120/the-acceptable-noise-level-benefit-from-directionality-for-listeners-with-severe-hearing-loss
#13
Mina Aghsoleimani, Hamid Jalilvand, Mohammad Ebrahim Mahdavi, Ahmad Reza Nazeri, Mohammad Kamali
Objectives: Directional microphone technology can enhance the speech intelligibility and listening comfort of listeners with hearing impairment. The main aim of this study is to investigate and compare the benefit derived by listeners with severe hearing loss from directional microphone technology with that derived by listeners with moderate hearing loss. Methods: The acceptable noise levels (ANLs) of two groups of listeners with moderate or severe hearing impairment (17 subjects in each group) were measured under unaided, omnidirectional-baseline-aided, and directional-aided conditions...
March 10, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29433161/the-allele-2-of-the-vntr-polymorphism-in-the-gene-that-encodes-a-natural-inhibitor-of-il-1%C3%AE-il-1ra-is-favorably-associated-with-chronic-otitis-media
#14
Maja Živković, Ivana Kolić, Snežana Jesić, Ana Jotić, Aleksandra Stanković
OBJECTIVES: Chronic otitis media (COM) is followed by irreversible tissue damage and destruction of the middle ear structures, with the possibility of complications under the maintenance of inflammation. Inflammatory mediators such as cytokines play a crucial role in the initial stage of inflammation. The aim of this study was to evaluate the association of the polymorphisms in two innate immunity/inflammation cascade genes from interleukin-1 (IL-1) gene cluster with COM with regard to cholesteatoma...
June 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29409312/impact-and-modulations-of-peripheral-and-edaphic-b-cell-subpopulations-in-chronic-rhinosinusitis-with-nasal-polyposis
#15
Pascal Ickrath, Norbert Kleinsasser, Xin Ding, Christian Ginzkey, Niklas Beyersdorf, Thomas Kerkau, Rudolf Hagen, Stephan Hackenberg
OBJECTIVES: The pathophysiological mechanisms of chronic rhinosinusitis with nasal polyposis (CRSwNP) still are discussed controversially. Regulatory B cells (Breg ) are responsible for the suppression of T cell activity: deficiencies for Breg have been demonstrated to contribute to autoimmune disorders, e.g., systemic lupus erythematosus. In order to evaluate the influence of B cell subpopulations, especially Breg , on the etiology of this disease, the aim of this study was to characterize subpopulations of peripheral and edaphic B cells in CRSwNP...
June 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29486541/efficacy-of-tympanoplasty-without-mastoidectomy-for-treating-chronic-otitis-media-in-patients-with-mastoid-cavity-opacification-in-temporal-bone-computed-tomography-findings
#16
Hantai Kim, Ho Young Bae, Oak-Sung Choo, Yun-Hoon Choung
OBJECTIVES: Combined mastoidectomy is generally preferred to tympanoplasty alone when treating patients with chronic otitis media (COM), particularly when temporal bone computed tomography (TBCT) shows that the mastoid cavity contains opacification of soft tissue density. However, in cases with Eustachian tube dysfunction, a mastoid cavity volume may be a burden to its function. We hypothesized that tympanoplasty alone might be better than tympanoplasty combined with mastoidectomy because soft tissue in the mastoid cavity is a sequel to a protective physiological response...
March 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29486540/comparison-of-treatment-outcomes-for-t3-glottic-squamous-cell-carcinoma-a-meta-analysis
#17
Bo Hae Kim, Sung Joon Park, Woo-Jin Jeong, Soon-Hyun Ahn
OBJECTIVES: This study compared the survival outcomes, local control rate, and laryngeal preservation rate of various treatment strategies in the treatment of T3 squamous cell carcinoma of the glottis using proportional meta-analyses. METHODS: Twenty-five retrospective case-series studies were included in these analyses. Treatment strategies were classified as total laryngectomy (TL), open partial laryngectomy (PL), transoral laser microsurgery (TLM), chemo-radiation therapy (CRT), and radiation therapy (RT) alone...
March 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29172396/the-effect-of-endoscopic-tympanoplasty-on-cochlear-function
#18
Isa Kaya, Goksel Turhal, Arin Ozturk, Sercan Gode, Cem Bilgen, Tayfun Kirazli
OBJECTIVES: The aim of this prospective clinical study was to measure the audiologic outcomes of the patients that underwent endoscopic transcanal cartilage tympanoplasty, and to investigate the effects on cochlear function. METHODS: Thirty-three patients (33 ears) who were diagnosed with noncomplicated chronic otitis media and underwent endoscopic transcanal cartilage tympanoplasty technique were included. Pre- and postoperative first month distortion product otoacoustic emission (DPOAE) signal-to-noise ratio (SNR), bone conduction hearing levels and air bone gap (ABG) values were measured and total endoscope usage time was noted...
March 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29032664/the-protective-effect-of-egb-761-against-3-nitropropionic-acid-induced-hearing-loss-the-role-of-sirtuin-1
#19
Mun Young Chang, Jihye Rhee, Shin Hye Kim, Young Ho Kim
OBJECTIVES: Local administration of 3-nitropropionic acid (3-NP) to the inner ear induces sensorineural hearing loss. Several studies have shown the otoprotective effects of ginkgo biloba extract EGb 761. Moreover, EGb 761 has been reported to activate Sirtuin 1 (SIRT1). The present study was designed to investigate whether EGb 761 prevents 3-NP-induced sensorineural hearing loss and determine its effects on the expression of SIRT1. METHODS: Sprague Dawley rats were divided into four experimental groups: control group receiving vehicle of 3-NP, EGb group receiving EGb 761, 3-NP group receiving 3-NP, and EGb+3-NP group receiving EGb 761 and 3-NP...
March 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29032663/number-of-metastatic-lymph-nodes-and-ratio-of-metastatic-lymph-nodes-to-total-number-of-retrieved-lymph-nodes-are-risk-factors-for-recurrence-in-patients-with-clinically-node-negative-papillary-thyroid-carcinoma
#20
Chuan-Ming Zheng, Yong Bae Ji, Chang Myeon Song, Ming-Hua Ge, Kyung Tae
OBJECTIVES: The number of metastatic lymph nodes (LNs) and the ratio between the number of metastatic LNs and the total number of retrieved LNs (the LN ratio [LNR]) have been proposed as risk factors for recurrence of papillary thyroid carcinoma (PTC). However, the significance of the number of LNs and the LNR in patients with clinically node negative PTC has not been clearly determined. The purpose of this study is to evaluate their significance. METHODS: We retrospectively analyzed 382 patients with PTC who had undergone total thyroidectomy with prophylactic central neck dissection (CND) between January 2000 and December 2010...
March 2018: Clinical and Experimental Otorhinolaryngology
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