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Journal of Human Reproductive Sciences

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https://www.readbyqxmd.com/read/30158820/outcomes-of-structured-psychotherapy-for-emotional-adjustment-in-a-childless-couple-diagnosed-with-recurrent-pregnancy-loss-a-unique-investigation
#1
Ansha Patel, N Dinesh, P S V N Sharma, Pratap Kumar, V S Binu
Losing a much-awaited pregnancy and an unborn child, time and again is known to be a painful experience in recurrent miscarriage or pregnancy loss (RPL). Literature on psychological consequences of RPL is abundant. Nonetheless, application of psychological intervention in RPL remains to be an overlooked area. Using a repeated measures design and standardized psychological measures, this case study assessed the outcomes of mindfulness-based therapy administered with routine fertility treatment in a couple with the history of recurrent miscarriages and secondary infertility...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158819/pregnancy-through-assisted-reproductive-technology-in-a-patient-with-thoracic-endometriosis-syndrome
#2
S Krishnakumar, Rohan Krishnakumar, Sonali Hiwale
Extrapelvic endometriosis is known to be difficult to diagnose. Appropriate management in an infertile patient with extrapelvic endometriosis is not only difficult but also not well established. This case report describes a patient with thoracic endometriosis syndrome who was managed successfully for controlling her pleural endometriosis and achieving a pregnancy through assisted reproductive technology (ART).
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158818/assisted-reproductive-techniques-in-a-patient-with-history-of-venous-thromboembolism-a-case-report-and-review-of-literature
#3
Sumana Gurunath, Sriprada Vinekar, Reeta Biliangady
We report a patient with a history of venous thrombosis following oral contraceptive pills who was planned for in vitro fertilization (IVF)-intracytoplasmic sperm injection for male factor infertility. This article discusses the mechanisms for predisposition to thrombosis during assisted reproduction in patients at high risk. Assessment of risk before commencement of treatment, use of mild stimulation, antagonist protocol, avoiding ovarian hyperstimulation, use of gonadotropin-releasing hormone agonist trigger and avoiding exposure to human chorionic gonadotropin, frozen embryo transfer in a natural cycle, single embryo transfer, avoiding multiple pregnancy, and use of prophylactic or therapeutic anticoagulation are the various risk-reduction strategies that must be adopted during IVF treatment to reduce the risk of thrombosis to that of natural conception...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158817/adult-granulosa-cell-tumor-a-sinister-differential-for-clomiphene-resistant-infertility
#4
Shalini Gainder, Japleen Kaur, Sujata Siwatch, Nalini Gupta
Granulosa cell tumors (GCTs) are rare sex cord-stromal tumors of the ovary. They may present with features of hyperestrogenism. We present a case of a 29-year-old nulliparous female, with infertility and oligomenorrhoea, initially managed with a provisional diagnosis of polycystic ovarian syndrome. She did not respond to multiple cycles of ovulation induction with clomiphene citrate. Later, an ovarian mass was detected, and she was initially planned for laparoscopy. Magnetic resonance imaging pelvis revealed a solid-looking mass in the ovary, with increased vascularity...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158816/illness-cognitions-anxiety-and-depression-in-men-and-women-undergoing-fertility-treatments-a-dyadic-approach
#5
Ansha Patel, P S V N Sharma, Pratap Kumar, V S Binu
Background: Emotional response to infertility is mediated by numerous interrelated psychological variables such as personality, health perceptions, cognitive appraisals, coping, and social support. While men and women respond to infertility differently, illness cognitions are a vital component of their emotional adjustment. The aim of this study is to compare the infertile men and women undergoing fertility treatments on perceived distress, helplessness, acceptance, benefits, anxiety, and depression...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158815/sociocultural-determinants-of-infertility-stress-in-patients-undergoing-fertility-treatments
#6
Ansha Patel, P S V N Sharma, Pratap Kumar, V S Binu
Introduction: Involuntary childlessness is a distressing condition that has considerable social implications in developing nations. Aim: The present study aims to investigate the less known sociocultural determinants of infertility stress in patients undergoing assisted conception and reproductive treatments. Methods: This cross-sectional research was conducted on 300 men and women with primary infertility. The profile of sociodemographic variables, clinical variables, and sociocultural variables was collected using a locally devised questionnaire...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158814/acceptance-of-donor-eggs-donor-sperms-or-donor-embryos-in-indian-infertile-couples
#7
Kaberi Banerjee, Bhavana Singla
Context: The reduction or loss of natural fertility is deeply painful in couples that are considering the use of donor gametes or donor embryos. This is the first study to assess the acceptability of donor gametes or embryos in Indian population. Aim: The aim of the study was to assess the attitude toward egg, sperm, and embryo donation among Indian the infertile couples. Settings: This study was conducted at infertility outpatient clinic New Delhi...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158813/one-plus-one-is-better-than-two-cumulative-reproductive-outcomes-are-better-after-two-elective-single-blastocyst-embryo-transfers-compared-to-one-double-blastocyst-embryo-transfer
#8
Vidhisha P Mehta, Jayesh A Patel, Reena H Gupta, Sandeep I Shah, Manish R Banker
Aims: The aim of this study is to compare cumulative in vitro fertilization-intracytoplasmic sperm injection outcomes following two elective single embryo transfer (eSET) versus one double embryo transfer (DET) using blastocyst(s). Settings and Design: This was retrospective observational study. Study Period: The study was conducted during January 2015-December 2015. Subjects and Methods: Forty-one fresh + 25 frozen eSET versus 123 DET using self-oocytes and 68 fresh + 35 frozen eSET versus 184 DET using donor-oocytes were included in the study...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158812/a-prospective-case-control-trial-to-evaluate-and-compare-the-efficacy-and-safety-of-atosiban-versus-placebo-in-in-vitro-fertilization-embryo-transfer-program
#9
Vineet Mishra, Himani Agarwal, Sugandha Goel, Priyankur Roy, Sumesh Choudhary, Sunita Lamba
Background: Recent developments in assisted reproductive technology focus on potential advances to improve its success rate. Atosiban, a combined oxytocin/vasopressin V1a receptor antagonist, is a novel class of drug involved in basic priming of the uterus for successful implantation during embryo transfer (ET). Objectives: The objective of this study is to evaluate the efficacy of atosiban (study group) in ET patients in comparison to placebo (control group) regarding implantation rate (IR), clinical pregnancy rate (CPR), and ongoing pregnancy rate and to assess the safety profile of atosiban...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158811/comparison-of-two-regimens-of-gonadotropin-releasing-hormone-antagonists-in-clomiphene-gonadotropin-induced-controlled-ovulation-and-intrauterine-insemination-cycles-randomized-controlled-study
#10
Sajja Devendra Siva Karthik, Alka Kriplani, Garima Kachhawa, Rajesh Khadgawat, Nutan Aggarwal, Neerja Bhatla
Context: Gonadotropin-releasing hormone (GnRH) antagonists in fixed or flexible regimens are used for prevention of premature luteinizing hormone (LH) surge, however, data comparing these regimens in stimulated intrauterine insemination (IUI) cycles are lacking. Aims: The aim of this study is to evaluate the effectiveness of GnRH antagonists in fixed and flexible regimens on the rate of premature luteinization (PL) and ovulation rate in sequential clomiphene-gonadotropin controlled ovulation-IUI cycles...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158810/methylenetetrahydrofolate-reductase-gene-specific-methylation-and-recurrent-miscarriages-a-case-control-study-from-north-india
#11
Kallur Nava Saraswathy, Lovejeet Kaur, Seerat Talwar, Jyoti Mishra, Suraj Huidrom, M P Sachdeva, Manju Puri
Aim: This study aimed to understand the association of gene-specific methylation of the promoter region of methylenetetrahydrofolate reductase (MTHFR) in the causation of recurrent miscarriages (RMs) both independently and also in light of MTHFR C677T polymorphism, hyperhomocysteinemia, folate, and Vitamin B12 deficiency. Settings and Design: This was a hospital-based, case-control, observational study. Methods: The proposed study included a total of 85 RM cases and 121 nonpregnant controls...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158809/screening-of-polymorphisms-of-transcription-factor-7-like-2-gene-in-polycystic-ovary-syndrome-using-polymerase-chain-reaction-restriction-fragment-length-polymorphism-analysis
#12
Yogamaya D Prabhu, Nishu Sekar, V G Abilash
Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder occurring in premenopausal women, with a prevalence rate of 5%-7%. It has been observed in multiple number of studies the coexistence between diabetes mellitus 2 and obesity with this endocrinopathic disorder. Transcription factor 7-like 2 (TCF7L2) gene is shown to be associated with insulin secretion. Aim: To screen whether the gene variant of TCF7L2 (formerly TCF4) gene is significantly associated and has susceptibilities with type 2 diabetes in PCOS...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158808/women-diagnosed-with-endometriosis-show-high-serum-levels-of-diethyl-hexyl-phthalate
#13
Sadia Nazir, Zeenat Usman, Muneer Imran, Khalid Pervaiz Lone, Gulfam Ahmad
Background: Endometriosis is one of the common causes of infertility with very diverse etiology. In modern lifestyle, humans are exposed to several endocrine-disrupting chemicals (EDCs) which may lead to reproductive disturbances. Diethyl hexyl phthalate (DEHP) is one of the common EDCs to which women are exposed by the use of cosmetics, perfumes, food packaging, medicine, and insecticides. Aim: The aim of this study was to measure the levels of DEHP in women diagnosed with endometriosis and healthy females and to compare these levels among different stages of endometriosis...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158807/role-of-autologous-bone-marrow-derived-stem-cell-therapy-for-follicular-recruitment-in-premature-ovarian-insufficiency-review-of-literature-and-a-case-report-of-world-s-first-baby-with-ovarian-autologous-stem-cell-therapy-in-a-perimenopausal-woman-of-age-45
#14
REVIEW
Shreya Gupta, Pooja Lodha, M Selva Karthick, Sunita Rajesh Tandulwadkar
Stem cell (SC) therapy has come up enormously, particularly for indications where not much can be done medically or surgically to improve the condition. SCs are the foundation cells for every organ, tissue, and cell in the body, and it can either reproduce into a SC or differentiate into specialized types of cells. Premature ovarian insufficiency (POI) is a clinical syndrome defined by loss of ovarian activity before the age of 40 years. POI is characterized by menstrual disturbance (amenorrhea or oligomenorrhea) with raised gonadotropins, low anti-Mullerian hormone (AMH), and estradiol level...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158806/urinary-versus-recombinant-gonadotropins-for-ovarian-stimulation-in-women-undergoing-treatment-with-assisted-reproductive-technology
#15
REVIEW
Ameet Patki, Himanshu Bavishi, Chandravati Kumari, Jayarani Kamraj, M Venugopal, K U Kunjimoideen, Poornima Nadkarni, Samundi Sankari, Sunil Chaudhary, M J Sangeeta, C S Manjunath, Pratap Kumar
Globally, about 10%-15% couples are affected by infertility, with major role being played by the couple's lifestyle. Several gonadotropin preparations (urinary, purified urinary, recombinant, and biosimilars) are available for use. Purified urinary formulations offer numerous advantages over their predecessor, including lesser injection dose required, ability to be administered subcutaneously, less batch-to-batch variability, better efficacy, ability to individualize protocols as per patient's need, better control of developing follicles, less risk of multiple pregnancies, and hyperstimulation...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158805/consensus-statement-on-the-use-of-oral-contraceptive-pills-in-polycystic-ovarian-syndrome-women-in-india
#16
(no author information available yet)
Objective: To provide consensus recommendations for health-care providers on the use of oral contraceptive pills (OCPs) in polycystic ovarian syndrome (PCOS) women in India. Participants: Extensive deliberations, discussions, and brainstorming were done with different fraternities (specialists) being involved. These included endocrinologists, gynecologists, reproductive endocrinologists, dermatologists, public health experts, researchers, and a project manager with a team to develop the guideline...
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158804/maximum-number-of-embryos-to-be-transferred-in-assisted-reproductive-technologies-cycle-ethics-opinion
#17
(no author information available yet)
Prevention of multiple pregnancies is of utmost importance as with multiple pregnancy-assisted reproductive technologies results shifts from success to complications. There is an increase in the maternal and neonatal morbidity and mortality with occurrence of higher order pregnancies. Therefore, restricting the number of embryos transferred either to one or two would reduce the occurrence of multiple pregnancy.
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158803/provision-of-fertility-services-for-women-at-increased-risk-of-complications-ethics-opinion
#18
(no author information available yet)
Certain medical conditions can increase the risk to the mother during pregnancy. This can increase the risk of maternal morbidity or severe morbidity. If pregnancy is decided upon after expert counseling, a multidisciplinary team should provide care.
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158802/upper-age-limit-for-assisted-reproductive-technologies-ethics-opinion
#19
(no author information available yet)
Fertility in women is closely related to reproductive age and becomes significantly compromised before the onset of perimenopausal menstrual irregularity. There is decrease in oocyte quality with age which is reflected by the increase of chromosomal aberrations in the oocytes and embryos. Oocyte or embryo donation to women of advanced age should be discouraged.
April 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/30158801/fertility-treatment-in-couples-with-seropositivity-for-human-immunodeficiency-virus-ethics-opinion
#20
(no author information available yet)
Human immunodeficiency virus results in acquired immunodeficiency syndrome which alters the immune system. The virus can be transmitted through contact with infected semen, vaginal fluids, or blood.
April 2018: Journal of Human Reproductive Sciences
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