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Journal of Human Reproductive Sciences

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https://www.readbyqxmd.com/read/29430160/a-case-of-primary-amenorrhea-with-swyer-syndrome
#1
Pritti K Priya, Vineet V Mishra, Sumesh Choudhary, Jamal S Rizvi
Swyer syndrome with complete gonadal dysgenesis is associated with an absence of testicular differentiation in a phenotypic female with a 46, XY karyotype. A 14-year-old unmarried girl was referred with complaints of primary amenorrhea and nondevelopment of breast. Her built was normal. Examination of her secondary sexual characteristics revealed no breast development, absent axillary hairs, and sparse pubic hairs. External genitalia was of female type. Karyotype showed genotype of 46, XY. Magnetic resonance imaging revealed hypoplastic uterus with absent fallopian tubes and ovaries...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29430159/prevalence-of-cytogenetic-anomalies-in-couples-with-recurrent-miscarriages-a-case-control-study
#2
Vishali Kalotra, Meena Lall, Pushpa Saviour, Ishwar Chander Verma, Anupam Kaur
Background: About 15%-20% of couples get affected by recurrent miscarriages (RM) and chromosomal abnormality in one partner affects 3%-6% of RM couples. Aims: The present study aimed to determine the prevalence of cytogenetic anomalies in couples with RM. Settings and Design: A case-control study was undertaken, in which 243 couples who had experienced 2 or >2 miscarriages were investigated for chromosomal abnormalities and compared with 208 healthy, age-matched control couples who had at least one healthy live born and no history of miscarriages...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29430158/delayed-presentation-of-turner-syndrome-challenge-to-optimal-management
#3
Uma Kaimal Saikia, Dipti Sarma, Yogesh Yadav
Background: Turner syndrome (TS) is a chromosomal disorder associated with dysmorphic features and comorbidities, with recent trends focusing on early diagnosis for adequate management. Aim: The aim is to study the age and mode of presentation of TS, associated comorbidities and look for any correlation with the genotype. Material and Methods: This was a retrospective analysis of girls with TS attending the endocrinology clinic of a tertiary care center...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29430157/pregnancy-outcome-of-home-intravaginal-insemination-in-couples-with-unconsummated-marriage
#4
Kaberi Banerjee, Bhavana Singla
Unconsummated marriage are mainly due to vaginismus or erectile dysfunction. They contribute to about 5% of couples in an infertility clinic. Their incidence is increasing in the metropolitan cities because of stressful lifestyles. Many of couples are advised intrauterine insemination as fertility treatment. However, home insemination is a simple, inexpensive and effective way of achieving pregnancy in such couples. We present the first study to document pregnancy rates of artificial home intravaginal insemination in couples with unconsummated marriage...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29430156/effect-of-endometrial-cavity-fluid-on-pregnancy-rate-of-fresh-versus-frozen-in-vitro-fertilization-cycle
#5
Nitika Gupta, Shilpa Bhandari, Pallavi Agrawal, Ishita Ganguly, Aparna Singh
Objective: This study aims to study the difference in etiology and outcome in terms of implantation rate and abortion rate in fresh (self-stimulated) versus frozen (oocyte donation cycle) in vitro fertilization (IVF) and in transient versus persistent fluid. Material and Methods: This retrospective study was conducted in the Department of Reproductive Medicine of tertiary care center from January 2012 to November 2015. Data were collected retrospectively from the departmental files...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29430155/does-perifollicular-vascularity-on-the-day-of-oocyte-retrieval-affect-pregnancy-outcome-in-an-in-vitro-fertilization-cycle
#6
Nikita Naredi, Santosh Kumar Singh, Rajesh Sharma
Background: The vascularization status of ovarian follicles affects reproductive competence of oocytes and in turn embryo quality by regulating its oxygen supply. Transvaginal power Doppler ultrasound can noninvasively map this vascularity of the ovarian follicles. Thus, we aimed to study the association of perifollicular vascularity and pregnancy outcome in women while on treatment for an in vitro fertilization cycle. Material and Methods: A prospective study on 200 participants evaluated the vascularity of 1008 follicles on the day of oocyte retrieval to outline a map depicting perfusion of each follicle...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29430154/repeat-dose-of-gonadotropin-releasing-hormone-agonist-trigger-in-polycystic-ovarian-syndrome-undergoing-in-vitro-fertilization-cycles-provides-a-better-cycle-outcome-a-proof-of-concept-study
#7
Krishna Deepika, Pookilath Baiju, Praneesh Gautham, Rathore Suvarna, Vohra Arveen, Rao Kamini
Objective: Is a single dose of gonadotropin-releasing hormone agonist (GnRHa) trigger to induce final oocyte maturation in polycystic ovarian syndrome (PCOS) undergoing in vitro fertilization (IVF) cycles with GnRH antagonist protocol sufficient to provide optimal oocyte maturity? Design: This is a prospective, randomized, double-blind, proof-of-concept study. Setting: This study was carried out at a tertiary care center. Material and Methods: A total of 125 patients diagnosed with PCOS defined as per the ESHRE/ASRM Rotterdam criteria (2003) undergoing IVF in antagonist protocol were randomized into two groups...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29430153/the-impact-of-progesterone-level-on-day-of-hcg-injection-in-ivf-cycles-on-clinical-pregnancy-rate
#8
Jawa Ashmita, Swarankar Vikas, Garg Swati
Background: Premature progesterone rise (PPR) has long been implicated as contributing to implantation failure. Despite the use of gonadotropin-releasing hormone (GnRH) analogues, subtle increases in serum progesterone ( P 4 ) levels beyond a threshold progesterone concentration were observed on the day of trigger in controlled ovarian hyperstimulation cycles. Aims: The purpose of the study was to evaluate the incidence of PPR on the day of trigger in conventional IVF/ICSI cycles and its impact on clinical pregnancy rate...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29430152/ovulation-induction-using-clomiphene-citrate-using-stair-step-regimen-versus-traditional-regimen-in-polycystic-ovary-syndrome-women-a-randomized-control-trial
#9
K Agrawal, Shalini Gainder, Lakhbir K Dhaliwal, Vanita Suri
Objective: To determine the efficacy of the stair-step protocol (SSP) using clomiphene citrate (CC) in patients with polycystic ovary syndrome (PCOS) and compare it with traditional regimen. Design: This was randomized control trial. Setting: Infertility Clinic. Patients: Sixty infertile PCOS women. Interventions: Patients were randomized into the study (SSP - 30 patients) and control group (traditional protocol - 30 patients)...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29430151/azoospermia-factor-c-subregion-of-the-y-chromosome
#10
REVIEW
Mili Nailwal, Jenabhai B Chauhan
The azoospermia factor (AZF) region on the Y chromosome consists of genes required for spermatogenesis. Among the three subregions, the AZFc subregion located at the distal portion of AZF is the driver for genetic variation in Y chromosome. The candidate gene of AZFc is known as deleted in azoospermia gene, which is studied with interest because it is involved in germ cell development and most frequently deleted genes leading to oligozoospermia and azoospermia. Recently, two partial deletions in AZFc gr/gr and b2/b3 are characterized at the molecular level which showed homologous recombination between amplicons, affecting spermatogenesis process...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29430150/on-the-origins-of-the-semen-analysis-a-close-relationship-with-the-history-of-the-reproductive-medicine
#11
REVIEW
Fernando Tadeu Andrade-Rocha
The spermatozoa were first seen in ejaculates in the 17 th century. However, the basic mechanisms of human fertilization have been only fully understood after the discovery of ovum in 1827. As a result, the interest in developing technologies for semen analysis arose from the early 1900s. Indeed, standard methodologies for semen analysis were designed mostly along the first half of the 20 th century. Before the 1930s, semen analysis was nearly unavailable clinically, since there were still no robust methodologies for assessing sperm characteristics, as well as to set up standard references that could be able to assess the reproductive capacity of men...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29430149/from-the-editor-s-desk
#12
EDITORIAL
Madhuri Patil
No abstract text is available yet for this article.
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29142455/large-volume-paracentesis-up-to-27-l-with-adjuvant-vaginal-cabergoline-in-the-case-of-severe-ovarian-hyperstimulation-syndrome-with-successful-pregnancy-outcome-a-case-report
#13
Nupur Agarwal, Sanghamitra Ghosh, Shikha Bathwal, Baidyanath Chakravarty
Severe ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening complication of assisted reproductive technology. Herein, we report the case of an infertile couple, with the husband being azoospermic, who underwent in-vitro fertilisation and intracytoplasmic sperm injection at our institute. The woman presented with late OHSS 7 days after embryo transfer. Inpatient management was performed with intensive surveillance. Oral cabergoline was started prophylactically but was replaced by the vaginal route due to intolerance...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29142454/successful-reproductive-outcome-after-laparoscopic-strassmann-s-metroplasty
#14
S D S Karthik, Alka Kriplani, Reeta Mahey, Garima Kachhawa
Mullerian anomalies cause a significant impact on the reproductive outcomes. A bicornuate uterus is a type of lateral fusion defect, which constitutes 26% of all uterine anomalies. Strassmann's metroplasty is a unification procedure performed to correct the two smaller uterine cavities into a more spacious single cavity. Improved reproductive performance was reported after unification metroplasty. Laparoscopic route can be adopted for this procedure with all the advantages of minimally invasive surgery. Here, we report a success story of a woman who suffered with six miscarriages and secondary infertility who underwent laparoscopic Strassmann's metroplasty in a tertiary care center and later delivered a baby by caesarean section...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29142453/ectopic-ovary-with-dermoid-cyst-as-a-result-of-possible-asymptomatic-autoamputation
#15
Bimal Mathew John
A 32-year-old woman, who presented for laparoscopic sterilization after two full-term normal deliveries, was incidentally diagnosed to have a left-sided complex cyst in the pouch of Douglas (POD). She had no history of previous surgeries or any symptoms of lower abdominal pain, nausea, or vomiting in the past. She underwent laparoscopy, and the left ovary and distal portion of the fallopian tube were absent in their normal position. An ectopic left ovary with dermoid cyst was noted in the POD. The right ovary and tube were in their normal position...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29142452/infertility-stress-in-couples-undergoing-intrauterine-insemination-and-in-vitro-fertilization-treatments
#16
Manisha Awtani, Kamayani Mathur, Sandeep Shah, Manish Banker
Aim: The main aim of the study was to assess the stress levels of husbands and wives undergoing intrauterine insemination (IUI) and in vitro fertilization (IVF) treatments, and also to observe whether the stress levels differed between the methods of treatments. Materials and Methods: This research focused on 120 infertile couples who underwent IUI and In Vitro Fertilization-Intra Sperm Cytoplasmic sperm Injection (IVF-ICSI) at an infertility clinic from April 2014 to November 2014...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29142451/sexual-functioning-beliefs-about-sexual-functioning-and-quality-of-life-of-women-with-infertility-problems
#17
Prathibha Agustus, Manjula Munivenkatappa, Padmini Prasad
Background: The study was conducted in the background of paucity of studies examining the sexual and psychosocial functioning of women with infertility. Aims: The study explored sexual functioning in women with infertility problems, their beliefs about sexuality and their quality of life. Settings and Design: A single group exploratory design with non-probability purposive sampling was used. A total of 30 participants diagnosed with primary infertility were included in the study...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29142450/autologous-intrauterine-platelet-rich-plasma-instillation-for-suboptimal-endometrium-in-frozen-embryo-transfer-cycles-a-pilot-study
#18
Sunita R Tandulwadkar, Manasi V Naralkar, Akash D Surana, M Selvakarthick, Avinash H Kharat
Introduction: This pilot study was to evaluate the effectiveness of intrauterine infusion of autologous platelet-rich plasma (PRP) in infertile women undergoing frozen embryo transfer cycles with suboptimal endometrium. Material and Methods: Intrauterine instillation of autologous PRP was done in 68 women between 22 and 40 years, over 8 months, with suboptimal endometrial growth, and patients with repeated cycle cancellations, in addition to Estradiol valerate. Frozen embryo transfer was performed when the endometrium reached an optimal pattern in terms of thickness, appearance, and vascularity...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29142449/single-blastocyst-transfer-the-key-to-reduce-multiple-pregnancy-rates-without-compromising-the-live-birth-rate
#19
Uma M Sundhararaj, Monali V Madne, Reeta Biliangady, Sumana Gurunath, Ambika G Swamy, Indu S T Gopal
Background: Historically, to achieve higher pregnancy rates, multiple embryos were transferred after an in-vitro fertilisation (IVF). However, this practice is being reassessed, because it leads to multiple pregnancies that is known to cause adverse maternal and fetal outcomes. Aim: To compare the pregnancy outcomes in fresh IVF or intracytoplasmic sperm injection (ICSI) cycles among women undergoing elective single blastocyst transfer (eSBT) vs. those undergoing double blastocyst transfer (DBT)...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29142448/expression-of-the-bone-morphogenetic-protein-2-bmp2-in-the-human-cumulus-cells-as-a-biomarker-of-oocytes-and-embryo-quality
#20
Sirin B Demiray, Ozlem Yilmaz, Ege N T Goker, Erol Tavmergen, Nilufer Calimlioglu, Ugur Sezerman, Huseyin O Soykam, Gulperi Oktem
Background: The members of the transforming growth factor-B superfamily, as the bone morphogenetic proteins (BMPs) subfamily and anti-Müllerian hormone (AMH), play a role during follicular development, and the bone morphogenetic protein-2 (BMP2), AMH, and THY1 are expressed in ovaries. Aim: This study was designed to define whether or not the expressions of these proteins in human cumulus cells (CCs) can be used as predictors of the oocyte and embryo competence...
July 2017: Journal of Human Reproductive Sciences
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