M Rampichová, E Košt'áková Kuželová, E Filová, J Chvojka, J Šafka, M Pelcl, J Daňková, E Prosecká, M Buzgo, M Plencner, D Lukáš, E Amler
Additive manufacturing, also called 3D printing, is an effective method for preparing scaffolds with defined structure and porosity. The disadvantage of the technique is the excessive smoothness of the printed fibers, which does not support cell adhesion. In the present study, a 3D printed scaffold was combined with electrospun classic or structured nanofibers to promote cell adhesion. Structured nanofibers were used to improve the infiltration of cells into the scaffold. Electrospun layers were connected to 3D printed fibers by gluing, thus enabling the fabrication of scaffolds with unlimited thickness...
November 13, 2017: Cell Adhesion & Migration