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Journal of Medical Imaging and Radiation Oncology

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https://www.readbyqxmd.com/read/29336109/moderate-hypofractionation-for-prostate-cancer-a-user-s-guide
#1
REVIEW
David I Pryor, Sandra L Turner, Keen Hun Tai, Colin Tang, Giuseppe Sasso, Marcus Dreosti, Henry H Woo, Lee Wilton, Jarad M Martin
Three large randomised controlled trials have been published in the last year demonstrating the non-inferiority of moderate hypofractionation compared to conventional fractionation for localised prostate cancer with respect to both disease control and late toxicity at 5 years. Furthermore, no clinically significant differences in patient-reported outcomes have emerged. More mature follow-up data are now also available from phase 2 studies confirming that moderate hypofractionation is associated with low rates of significant toxicity at 10 years...
January 16, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29330968/correlation-of-dynamic-contrast-enhanced-mri-derived-volume-transfer-constant-with-histological-angiogenic-markers-in-high-grade-gliomas
#2
Ningning Di, Chenjun Yao, Wenna Cheng, Yan Ren, Jianxun Qu, Bin Wang, Zhenwei Yao
INTRODUCTION: To ascertain if the volume transfer constant (Ktrans ) derived from T1 dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) correlates with the immunohistological markers of angiogenesis in high-grade gliomas. METHODS: Fifty-one image-guided biopsy specimens in 34 patients with newly presenting high-grade gliomas (grade III = 16; grade IV = 18) underwent preoperative imaging (conventional imaging and T1 DCE-MRI). We correlated vascular endothelial growth factor (VEGF) expression and the microvessel density (MVD) of MRI-guided biopsy specimens with the corresponding DCE-derived Ktrans ...
January 13, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29316375/selection-criteria-for-endovascular-therapy-for-acute-ischaemic-stroke-are-patients-missing-out
#3
Julian Maingard, Leonid Churilov, Peter Mitchell, Richard Dowling, Bernard Yan
INTRODUCTION: Endovascular clot retrieval (ECR) following intravenous thrombolysis is superior to intravenous thrombolysis alone for acute stroke with large vessel occlusion. However, trial selection criteria may exclude potentially salvageable patients. We investigated the impact of published selection criteria on the different proportions of patients excluded and clinical outcome. METHODS: We included patients with anterior circulation stroke treated with ECR from a single centre...
January 9, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29314703/a-retrospective-cost-analysis-of-angioplasty-compared-to-bypass-surgery-for-lower-limb-arterial-disease-in-an-australian-tertiary-health-service
#4
Natalie Ly Ngu, James Lisik, Dinesh Varma, Gerard S Goh
INTRODUCTION: Percutaneous transluminal angioplasty (PTA) and surgical bypass (BYP) are treatment options for symptomatic peripheral arterial disease (PAD). PTA and BYP have different clinical outcomes and cost implications. This paper aims to compare hospital-related costs of PTA and BYP for PAD of the lower limbs in an Australian health service. METHODS: A retrospective cost analysis using clinical and financial data from an urban, tertiary hospital was performed...
January 5, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29271078/immediate-post-insertion-tip-migration-of-peripherally-inserted-central-catheters-dependent-on-arm-position-and-depth-of-inspiration
#5
Bruno R De Carvalho, Gerard M Eagar
INTRODUCTION: The purpose of this study is to assess the degree of PICC tip migration with breathing and arm movement to determine whether accurate positioning is feasible or futile. METHODS: A prospective cohort of 218 consecutive patients undergoing PICC insertion at our institution between January and August 2015 was selected, of which 129 met inclusion criteria. The position of insertion was used as control with the arm at 90° during inspiration, followed by three study images: expiration with arm unchanged, inspiration with arm fully adducted and inspiration with arm fully abducted...
December 22, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29271056/under-utilisation-of-high-dose-rate-brachytherapy-boost-in-men-with-intermediate-high-risk-prostate-cancer-treated-with-external-beam-radiotherapy
#6
Wee Loon Ong, Sue M Evans, Jeremy L Millar
INTRODUCTION: The aim of this study was to evaluate the use of high-dose-rate brachytherapy (HDR-BT) boost with definitive external beam radiotherapy (EBRT) in prostate cancer (CaP) management. METHODS: The study population comprised men with intermediate-high risk CaP captured in the population-based Prostate Cancer Outcome Registry Victoria (PCOR-Vic), treated with EBRT from January 2010 to December 2015. The primary outcome is the proportion of men who received HDR-BT boost...
December 22, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29235731/collaborative-model-for-training-and-credentialing-point-of-care-ultrasound-6-year-experience-and-quality-outcomes
#7
Carolynne J Cormack, Peter R Coombs, Kate E Guskich, Gabriel E Blecher, Neil Goldie, Ronnie Ptasznik
INTRODUCTION: Point-of-care ultrasound (PoCUS) is a rapidly growing area, providing physicians with a valuable diagnostic tool for patient assessment. This paper describes a collaborative model, utilising radiology department ultrasound expertise, to train and credential physicians in PoCUS. A 6-year experience of the implementation and outcomes of the programme established within the emergency departments of a large, multi-campus hospital network are presented. METHODS: A collaborative model was initially developed and implemented between radiology and emergency departments...
December 13, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29230956/prevalence-of-non-18-f-fluorodeoxyglucose-avid-incidental-findings-of-clinical-significance-on-whole-body-positron-emission-tomography-computed-tomography-a-review-of-500-consecutive-cases
#8
James A Sheldon, Kelvin K Yap, Kim L Taubman, Stephen M Schlicht
INTRODUCTION: The prevalence of incidental 18 F-fluorodeoxyglucose (FDG)-avid findings on positron emission tomography-computed tomography (PET/CT) has been extensively described. Few studies, however, have assessed the prevalence and significance of non-FDG-avid findings; pathology that is identified on review of the low-dose, non-contrast CT. The aim of this study was to determine the overall prevalence of non FDG-avid incidental findings on PET/CT and the prevalence of 'clinically significant' non FDG-avid pathology...
December 11, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29230951/the-artefacts-of-death-ct-post-mortem-findings
#9
Tom Sutherland, Chris O'Donnell
Post-mortem CT is an increasingly used tool for investigating cause of death. While sharing many similarities with pre-mortem imaging, a number of unique artefacts occur at post-mortem CT, and these have the potential to mask underlying disease processes. It is vital that the artefacts associated with the process of dying and decompositional changes are recognised to avoid misdiagnosis. The following pictorial review discusses and illustrates the important and common post-mortem changes.
December 11, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29222833/association-between-measures-of-treatment-quality-and-disease-progression-in-prostate-cancer-radiotherapy-an-exploratory-analysis-from-the-trog-03-04-radar-trial
#10
Marco Marcello, Martin A Ebert, Annette Haworth, Allison Steigler, Angel Kennedy, Max Bulsara, Rachel Kearvell, David J Joseph, James W Denham
INTRODUCTION: Quality assurance methods are incorporated into multicentre radiotherapy clinical trials for ensuring consistent application of trial protocol and quantifying treatment uncertainties. The study's purpose was to determine whether post-treatment disease progression is associated with measures of the quality of radiotherapy treatment. METHODS: The TROG 03.04 RADAR trial tested the impact of androgen deprivation on prostate cancer patients receiving dose-escalated external beam radiation therapy...
December 8, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29193849/apparent-transverse-relaxation-r2%C3%A2-on-mri-as-a-method-to-differentiate-treatment-effect-pseudoprogression-versus-progressive-disease-in-chemoradiation-for-malignant-glioma
#11
Jean-Guy Belliveau, Glenn S Bauman, David Macdonald, Maria Macdonald, L Martyn Klassen, Ravi S Menon
INTRODUCTION: Pseudoprogression (psPD) is a transient post-treatment imaging change that is commonly seen when treating glioma with chemotherapy and radiation. The use of apparent transverse relaxation rate (R2∗), which is calculated from a contrast-free multi-echo gradient echo Magnetic Resonance Imaging (MRI) sequence, may allow for quantitative identification of patients with suspected psPD. METHODS: We acquired a multi-echo gradient echo sequence using a 3T-Siemens Prisma MRI...
November 30, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29193781/impact-of-tumour-motion-compensation-and-delineation-methods-on-fdg-pet-based-dose-painting-plan-quality-for-nsclc-radiation-therapy
#12
Hannah Mary Thomas, Paul E Kinahan, James Jebaseelan E Samuel, Stephen R Bowen
INTRODUCTION: To quantitatively estimate the impact of different methods for both boost volume delineation and respiratory motion compensation of [18F] FDG PET/CT images on the fidelity of planned non-uniform 'dose painting' plans to the prescribed boost dose distribution. METHODS: Six locally advanced non-small cell lung cancer (NSCLC) patients were retrospectively reviewed. To assess the impact of respiratory motion, time-averaged (3D AVG), respiratory phase-gated (4D GATED) and motion-encompassing (4D MIP) PET images were used...
November 28, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29139207/patient-reported-outcomes-of-slow-single-arc-rotation-do-we-need-rotating-gantries
#13
Brendan Whelan, Miriam Welgampola, Leigh McGarvie, Kuldeep Makhija, Robin M Turner, Lois Holloway, Ilana Feain, Michael Jackson, Michael Barton, Paul Keall
INTRODUCTION: Patient rotation could greatly simplify radiation therapy delivery, with particularly important ramifications for fixed beam treatment with protons, heavy ions, MRI-Linacs, and low cost Linacs. Patient tolerance is often cited as a barrier to widespread implementation to patient rotation; however, no quantitative data addressing this issue exists. In this study, patient reported experiences of slow, single arc rotation in upright (sitting) and lying orientations are reported...
November 15, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29119692/impact-of-same-day-vs-day-before-pre-operative-lymphoscintigraphy-for-sentinel-lymph-node-biopsy-for-early-breast-cancer-local-australian-experience
#14
Yang Yang Huang, Amelie Maurel, Saud Hamza, Lee Jackson, Zeyad Al-Ogaili
INTRODUCTION: To assess the impact of delayed vs immediate pre-operative lymphoscintigraphy (LSG) for sentinel lymph node biopsy in a single Australian tertiary breast cancer centre. METHODS: Retrospective cohort study analysing patients with breast cancer or DCIS who underwent lumpectomy or mastectomy with pre-operative LSG and intra-operative sentinel lymph node biopsy from January 2015 to June 2016. RESULTS: A total of 182 LSG were performed...
November 9, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29080296/targeting-general-practitioners-prospective-outcomes-of-a-national-education-program-in-radiation-oncology
#15
Lucinda Morris, Peter Gorayski, Sandra Turner
INTRODUCTION: We report on learning outcomes of a standardized national education program aimed at improving general practitioner (GP) knowledge about radiation therapy (RT) and referral pathways to radiation oncologists (ROs). METHODS: In 2014, a GP education program was developed through the Targeting Cancer public awareness campaign of the Royal Australian and New Zealand College of Radiologists (RANZCR) Faculty of Radiation Oncology. The sessions were held in RT departments and comprised of RO-led case-based group learning and a department tour...
October 28, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29080287/contemporary-salvage-post-prostatectomy-radiotherapy-early-implementation-improves-biochemical-control
#16
Andrew Kneebone, George Hruby, Georgia Harris, Kris Rasiah, Justin Vass, Deborah Whalley, Philip McCloud, Sandra Louw, Linxin Guo, Thomas Eade
INTRODUCTION: The optimal time to commence salvage radiotherapy (SRT) for a rising PSA post radical prostatectomy is not known. We wished to assess the impact of index PSA (iPSA) level prior to SRT on rates of biochemical failure (BCF) post treatment. METHODS: Patients referred to our institution for SRT for a rising PSA post surgery were accrued onto a prospective database. Baseline demographic data, tumour and treatment factors were collected including pathologic T and N stage, margin status, Gleason score (GS), lymphovascular space invasion (LVSI), use of androgen deprivation therapy (ADT) and time from surgery to salvage radiotherapy...
October 28, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29076238/retrospective-review-of-ct-guided-intervertebral-disc-biopsies-performed-at-a-tertiary-referral-centre-for-suspected-osteodiscitis
#17
Kylie Lopes Floro, Wendy Munckhof, John Coucher
INTRODUCTION: Patients with osteodiscitis are often prescribed antibiotics prior to biopsy. There is controversy in the literature about whether antibiotic pre-treatment prior to CT-guided biopsy decreases the microbiological culture yield. Conclusions from previous studies are influenced by sample size error and selection bias. Our study, conducted in a large number of patients over a 10-year period, clarifies this issue so that best clinical practice is assured. METHODS: We performed a retrospective audit of the clinical, radiological and microbiological features of adult patients who underwent CT-guided biopsies for suspected osteodiscitis at a tertiary institution...
October 27, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29071800/national-survey-on-image-guided-radiotherapy-practice-in-new-zealand
#18
Jerusha Padayachee, Jasmin Loh, Albert Tiong, Louis Lao
INTRODUCTION: This survey aimed to assess the use of image-guided radiotherapy (IGRT) within New Zealand (NZ) and evaluate the quality of IGRT delivery. METHOD: All nine centres in NZ were invited to participate in an online survey in November 2015. Questions were asked on type of IGRT technologies available, IGRT use by tumour site and frequency of imaging. In addition, questions were asked in reference to the American Society for Radiation Oncology (ASTRO) White Paper recommendations on safe practice of IGRT...
October 26, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29067775/dual-phase-hybrid-18-f-fluoride-positron-emission-tomography-mri-in-ankylosing-spondylitis-investigating-the-link-between-mri-bone-changes-regional-hyperaemia-and-increased-osteoblastic-activity
#19
Lino M Sawicki, Susanne Lütje, Xenofon Baraliakos, Jürgen Braun, Julian Kirchner, Johannes Boos, Philipp Heusch, Verena Ruhlmann, Ken Herrmann, Lale Umutlu, Harald H Quick, Gerald Antoch, Christian Buchbender
INTRODUCTION: Focal (18) F-Fluoride uptake on blood-pool phase PET represents regional hyperaemia, while it indicates osteoblastic activity on mineralization phase PET. This study investigates the link between regional hyperaemia and osteoblastic activity in inflammatory and chronic lesions of ankylosing spondylitis (AS) of the sacroiliac joints (SIJ) using dual-phase (18) F-Fluoride PET/MRI. METHODS: Thirteen patients (six men, seven women, age: 37 ± 10 years) with active AS prospectively underwent dual-phase (18) F-Fluoride PET/MRI...
October 25, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29210211/continuing-professional-development
#20
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December 2017: Journal of Medical Imaging and Radiation Oncology
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