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Acta Ophthalmologica

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https://www.readbyqxmd.com/read/30426693/a-nationwide-population-based-study-of-social-demographic-factors-associated-diseases-and-mortality-of-keratoconus-patients-in-denmark-from-1977-to-2015
#1
Sashia Bak-Nielsen, Cecilia H Ramlau-Hansen, Anders Ivarsen, Oleguer Plana-Ripoll, Jesper Hjortdal
PURPOSE: To study sociodemographic factors, associated diseases and survival of Danish keratoconus patients. METHODS: All patients diagnosed with keratoconus 1977-2015 (n = 2679) were matched to 10 persons who had not been diagnosed with keratoconus (n = 26 790). Conditional logistic regression assessed whether sociodemographic factors and specific systemic diseases were associated with the odds of keratoconus. Mortality was assessed with time-to-event analysis...
November 13, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30421562/igg4-related-disease-in-patients-with-idiopathic-orbital-inflammation-syndrome-data-from-the-french-sioi-prospective-cohort
#2
Sébastien Abad, Antoine Martin, Francoise Héran, Nahla Cucherousset, Frédéric Mouriaux, Emmanuel Héron, Neila Sédira, Mathieu Zmuda, Matthieu Groh, Aïcha Abbas, David Saadoun, Pierre Aucouturier, Eric Vicaut, Robin Dhote
PURPOSE: To better characterize IgG4-related disease (RD) in the setting of idiopathic orbital inflammation syndrome (IOIS). METHODS: National, multicentre, prospective, observational cohort study. Among the patients consecutively included in the French multicentre SIOI cohort, we selected those who underwent orbital and/or adnexal biopsy. Clinical, morphological and pathological findings at diagnosis were blindly analysed. Serum IgG4 levels at inclusion were measured and all available biopsy specimens were immunostained for IgG4 and IgG...
November 12, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30421526/biomechanical-efficacy-of-contact-lens-assisted-collagen-cross-linking-in-porcine-eyes
#3
Gregor Wollensak, Eberhard Spörl, Hermann Herbst
PURPOSE: Contact lens-assisted corneal cross-linking (CACXL) has been proposed for the cross-linking treatment in thin corneas. The aim of this study was to assess the biomechanical efficacy of this treatment. METHODS: Post-mortem porcine eyes were treated with standard cross-linking and with cross-linking placing a contact lens soaked with isoosmolar riboflavin solution on the debrided cornea with or without an adherent precorneal riboflavin film of up to 100 μm thickness...
November 12, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30414256/associations-of-cytokine-concentrations-in-aqueous-humour-with-retinal-vascular-abnormalities-and-exudation-in-coats-disease
#4
Juan Zhang, Chen Jiang, Lu Ruan, Xin Huang
PURPOSE: To investigate the associations of cytokine concentrations in aqueous humour with the severity of retinal vascular abnormalities, exudation and fibrosis in patients with Coats' disease. METHODS: Aqueous humour samples were collected in 23 paediatric patients (23 eyes) with Coats' disease and six age-matched control patients (six eyes) with congenital cataract in this cross-sectional, case-control study. Through Cytometric Bead Array technology, six angiogenic, inflammatory and fibrotic cytokines were measured for their concentrations in aqueous humour...
November 9, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30414255/efficacy-of-bevacizumab-for-posttraumatic-choroidal-neovascularization
#5
LETTER
Kwangsic Joo, Taewoong Um, Sang Jun Park, Joon Hee Cho, Jeeyun Ahn, Jee Taek Kim, Joo Yong Lee, Kyu Hyung Park, Se Joon Woo
No abstract text is available yet for this article.
November 9, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30411518/the-tick-sign-a-new-and-simple-test-to-diagnose-keratoconus-at-the-slit-lamp
#6
LETTER
Marcus-Matthias Gellrich
No abstract text is available yet for this article.
November 8, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30407733/automatic-computer-aided-analysis-of-optic-disc-pallor-in-fundus-photographs
#7
Hee Kyung Yang, Ji Eun Oh, Sang Beom Han, Kwang Gi Kim, Jeong-Min Hwang
PURPOSE: Assessment of optic disc pallor in fundus photographs may be frequently misinterpreted due to the subjective nature of interpretation. We developed a fully automatic computer-aided detection (CAD) system for optic disc pallor using colour fundus photographs and evaluated the accuracy of the system. METHODS: A newly proposed CAD system was developed for automated segmentation and image analysis of optic disc pallor, and a logistic regression model was developed for risk analysis...
November 8, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30402966/maternal-smoking-during-pregnancy-and-the-risk-of-strabismus-in-offspring-a-meta-analysis
#8
REVIEW
Yudi Yang, Chao Wang, Yong Gan, Heng Jiang, Wenning Fu, Shiyi Cao, Zuxun Lu
The effect of maternal smoking during pregnancy on strabismus in offspring remains unclear. We conducted a meta-analysis to summarize epidemiological evidences on the association between maternal smoking during pregnancy and the risk of offspring strabismus. Eligible studies were searched from the PubMed, Ovid, Embase and CNKI databases up to May 2018. The qualities of included articles were assessed with the Newcastle-Ottawa Scale and the assessment scale recommended by the Agency for Healthcare Research and Quality...
November 6, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30390381/new-compound-heterozygous-ush2a-mutations-in-usher-syndrome
#9
LETTER
Longhao Kuang, Qingshan Chen, Run Gan, Xiaohe Yan
No abstract text is available yet for this article.
November 2, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30390376/efficacy-of-lateral-eyelid-block-excision-with-canthoplasty-and-full-thickness-skin-grafting-in-lower-eyelid-cicatricial-ectropion
#10
Ilse Mol, Dion Paridaens
PURPOSE: To report on the outcomes of our preferred surgical technique for the correction of lower eyelid cicatricial ectropion METHODS: We conducted a retrospective, nonrandomized, interventional analysis of a consecutive case series of patients with cicatricial lower lid ectropion treated with adhesiolysis, lateral eyelid-block excision with canthoplasty and full-thickness skin grafting. Donor sites included the ipsi- or contralateral upper eyelid and pre- or retroauricular skin. All patients were treated by one of our oculoplastic surgeons in the period from January 2005 to January 2017 in the Rotterdam Eye Hospital/Focus Clinic Rotterdam...
November 2, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30390373/prevalence-of-anterior-polar-cataracts-in-children-and-risk-factors-for-amblyopia
#11
Asrin Rasul, Line Kessel
PURPOSE: Anterior polar cataract is an opacity in the anterior capsule of the lens. Anterior polar cataract has historically been considered as a relatively benign condition. The purpose of this study was to estimate the prevalence of anterior polar cataract, to identify the risk factors for amblyopia and to estimate the risk of developing amblyopia in children with anterior polar cataract. METHODS: The medical records for patients with congenital cataracts at the Eye Clinic Rigshospitalet, Rigshospitalet-Glostrup and Kennedy Center covering a ten year period from 2007 to 2016 (both metres  years included) were reviewed...
November 2, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30390370/toy-gun-eye-injuries-eye-protection-needed-helsinki-ocular-trauma-study
#12
Anna-Kaisa Haavisto, Ahmad Sahraravand, Päivi Puska, Tiina Leivo
PURPOSE: We report the epidemiology, findings, treatment, long-term outcome and use of resources for eye injuries caused by toy guns in southern Finland. METHODS: All new patients injured by toy guns in one year (2011-2012) and treated at Helsinki University Eye Hospital were included. Follow-ups occurred at 3 months and 5 years. RESULTS: Toy guns caused 15 eye traumas (1% of all eye traumas). Most patients were male (n = 14) and children aged under 16 years (n = 13)...
November 2, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30378287/genetic-influence-on-contrast-sensitivity-in-young-adults
#13
LETTER
Koen V Haak
No abstract text is available yet for this article.
October 30, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30378259/maladaptive-personality-traits-psychological-morbidity-and-coping-strategies-in-chronic-central-serous-chorioretinopathy
#14
Femke M van Haalen, Elon H C van Dijk, Cornelie D Andela, Greet Dijkman, Nienke R Biermasz, Alberto M Pereira, Camiel J F Boon
PURPOSE: 'Type A' behavioural characteristics and psychosocial stress have traditionally been associated with chronic central serous chorioretinopathy (cCSC). However, a characteristical personality profile could not be identified in these patients and the presumed association with stress is subject to controversy, due to a lack of convincing studies using validated measuring instruments. In this study, we aimed to assess maladaptive personality traits, psychological morbidity and coping strategies in patients with cCSC, in order to identify potentially modifiable psychosocial aspects which could be used in support to current standard treatment...
October 30, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30369094/are-the-real-life-outcomes-of-using-aflibercept-in-diabetic-macular-oedema-comparable-to-the-landmark-studies
#15
LETTER
Aisling K Higham, Muhammad I Tahir, Kavita Gala, Georgios Verroiopoulos
No abstract text is available yet for this article.
October 27, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30369090/macular-perfusion-velocities-in-the-ocular-ischaemic-syndrome
#16
Oliver Niels Klefter, Peter Kristian Kofoed, Inger Christine Munch, Michael Larsen
PURPOSE: To assess retinal perfusion in eyes with unilateral ocular ischaemic syndrome (OIS) and to compare with control subjects. METHODS: Retrospective case series. Linear blood flow velocities in macular vessels were estimated using motion-contrast fundus photography in eight patients with unilateral OIS (eight OIS eyes, seven fellow eyes) and 12 control subjects. The diagnosis of OIS was supported by carotid artery Doppler ultrasonography and pneumoplethysmographic measurement of ocular systolic perfusion pressure...
October 27, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30369070/reducing-avoidable-visual-impairment-in-elderly-home-healthcare-patients-by-basic-ophthalmologic-screening
#17
Ruth van Nispen, Hilde van der Aa, Frank Timmermans, Nikki Meijer, Nicole Koster, Jos de Blok, Jan Keunen, Ger van Rens
PURPOSE: To investigate the prevalence of potential age-related eye conditions in elderly who are assisted by home healthcare nurses. The number of referrals to the general practitioner (GP), feasibility of screening and associations between vision loss and health outcomes were also studied. METHODS: Cross-sectional study in which trained home healthcare nurses screened the eyes of 151 patients [mean age 80 (50-96 years)] using their available correction, with VISION 2020 Netherlands screeners (e...
October 27, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30369064/persisting-diplopia-after-periocular-injection-of-parallel-imported-kenalog-%C3%A2-triamcinolone-acetonide
#18
LETTER
Kåre Clemmensen, Mette Slot Nielsen, Susanne Krag
No abstract text is available yet for this article.
October 27, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30369062/bevacizumab-in-age-related-macular-degeneration-a-randomized-controlled-trial-on-the-effect-of-on-demand-therapy-every-4-or-8-weeks
#19
Sankha Amarakoon, José P Martinez-Ciriano, L Ingeborgh van den Born, Seerp Baarsma, Tom Missotten
PURPOSE: Intravitreal anti-vascular endothelial growth factor (VEGF) injections are an effective treatment for neovascular age-related macular degeneration (nARMD). Bevacizumab appears to be a cost-effective off-label anti-VEGF alternative to ranibizumab, but an optimal injection schedule has not yet been determined. In this study, we investigate whether on-demand bevacizumab treatment every 8 weeks is non-inferior to on-demand bevacizumab every 4 weeks in treating nARMD. METHODS: A total of 120 nARMD patients were randomly assigned to an on-demand regimen of intravitreal bevacizumab (IVB) every 4 (n = 60) or 8 weeks (n = 60)...
October 27, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/30367541/effects-of-bifocals-on-visual-acuity-in-children-with-down-syndrome-a-randomized-controlled-trial
#20
Christine de Weger, Nienke Boonstra, Jeroen Goossens
PURPOSE: Children with Down syndrome (DS) typically have reduced visual acuity (VA) and accommodation lag, but it is unclear whether prescribed glasses should correct both distance VA (DVA) and near VA (NVA) due to the lack of RCTs. We therefore conducted a multicentre RCT to compare the effects of bifocals designed to correct both DVA and NVA with distance-correcting unifocal glasses in children with DS. METHODS: A total of 119 children with DS, aged 2-16, were randomly allocated for bifocal or unifocal glasses (with full correction of refraction error in cycloplegia) in 14 Dutch hospitals and followed during 1 year...
October 27, 2018: Acta Ophthalmologica
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