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Acta Ophthalmologica

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https://www.readbyqxmd.com/read/28741902/corneal-confocal-sub-basal-nerve-plexus-evaluation-a-review
#1
REVIEW
Joanna Kokot, Adam Wylęgała, Bogumił Wowra, Łukasz Wójcik, Dariusz Dobrowolski, Edward Wylęgała
The aim of this study was to review the most recent data about corneal sub-basal nerve plexus (SNP) evaluated with the use of corneal confocal microscopy (CCM). For this purpose, an electronic search was conducted based on PubMed and Google Scholar and Web of Science databases from 2008 up to the end of 2016. Ninety-eight articles in English were cited, as well as abstracts in other languages, concerning the morphology and function of corneal SNP in various diseases. Changes in corneal SNP as a result of local treatment were also introduced...
July 25, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28696567/transplantation-of-amniotic-membrane-for-choroidal-hole-to-treat-suprachoroidal-silicone-oil-migration
#2
LETTER
Dongqing Zhu, Xiaoliang Jin, Jibo Zhou
No abstract text is available yet for this article.
July 11, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28692136/measurement-centration-and-zone-diameter-in-anterior-posterior-and-total-corneal-astigmatism-in-keratoconus
#3
Anneli Fredriksson, Anders Behndig
PURPOSE: To investigate the central and paracentral astigmatism and the significance of centration and measurement zone diameter compared to a 3-mm pupil-centred measurement zone in keratoconus and in healthy eyes. METHODS: Twenty-eight right eyes from 28 KC patients with an inferotemporal cone were selected according to specified criteria based on Oculus Pentacam HR(®) measurements and were matched with healthy control eyes. The flat (K1) and steep (K2) keratometry readings were registered from the 'Total Corneal Refractive Power' (TCRP) display as well as the anterior and posterior corneal astigmatism displays (ACA and PCA, respectively)...
July 10, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28677912/analysis-of-kera-in-four-families-with-cornea-plana-identifies-two-novel-mutations
#4
Lubica Dudakova, Jang Hee J Vercruyssen, Irina Balikova, Lavina Postolache, Bart P Leroy, Pavlina Skalicka, Petra Liskova
PURPOSE: To identify the molecular genetic cause in four families of various ethnic backgrounds with cornea plana. METHODS: Detailed ophthalmological examination and direct sequencing of the KERA coding region in five patients of Czech and Turkish origin and their available family members. RESULTS: Compound heterozygosity for a novel missense mutation c.209C>T; p.(Pro70Leu) and a novel splice site mutation c.887-1G>A in KERA were detected in two affected siblings of Czech origin...
July 5, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28677865/vascular-and-metabolic-comorbidities-in-open-angle-glaucoma-with-low-and-high-teen-intraocular-pressure-a-cross-sectional-study-from-south-korea
#5
Si Hyung Lee, Gyu Ah Kim, Wonseok Lee, Hyoung Won Bae, Gong Je Seong, Chan Yun Kim
PURPOSE: To assess the associations between vascular and metabolic comorbidities and the prevalence of open-angle glaucoma (OAG) with low-teen and high-teen intraocular pressure (IOP) in Korea. METHODS: Cross-sectional data from the Korean National Health and Nutrition Examination Survey from 2008 to 2012 were analysed. Participants diagnosed with OAG with normal IOP were further classified into low-teen IOP (IOP ≤ 15 mmHg) and high-teen IOP (15 mmHg < IOP ≤ 21 mmHg) groups...
July 5, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28677833/vitrectomy-with-a-modified-temporal-inverted-limiting-membrane-flap-to-reconstruct-the-foveolar-architecture-for-macular-hole-retinal-detachment-in-highly-myopic-eyes
#6
Tzyy-Chang Ho, Allen Ho, Muh-Shy Chen
PURPOSE: We investigated the surgical results of macular hole retinal detachment (MHRD) with a modified C-shaped temporal inverted internal limiting membrane (ILM) flap to reconstruct the foveolar architecture in highly myopic eyes. METHODS: Eighteen highly myopic eyes with MHRD in 17 patients who underwent a vitrectomy with a modified C-shaped temporal inverted ILM flap were followed for 12 months. Anatomic outcomes were evaluated by fundus examinations and optical coherence tomography...
July 5, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28671353/retinal-venous-pressure-is-higher-than-the-airway-pressure-and-the-intraocular-pressure-during-the-valsalva-manoeuvre
#7
Richard Stodtmeister, Maria Heyde, Sylvana Georgii, Egbert Matthè, Eberhard Spoerl, Lutz Ernst Pillunat
PURPOSE: The aims of this prospective experimental study were to explore the influence of the Valsalva manoeuvre (VM) on retinal venous pressure (RVP) in human volunteers in a university setting and to establish correlations for RVP with the increase in airway pressure (∆AirP) and in intraocular pressure (∆IOP). METHODS: In total, 31 healthy young volunteers (age: 24 ± 1.7 years) were investigated. The instruments used included a dynamic contour tonometer, a contact lens dynamometer (Imedos) and an electronic pressure transducer for measuring airway pressure...
July 3, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28671340/physical-activity-and-myopia-in-danish-children-the-champs-eye-study
#8
Kristian Lundberg, Anne Suhr Thykjaer, Rasmus Søgaard Hansen, Anders Højslet Vestergaard, Nina Jacobsen, Ernst Goldschmidt, Rodrigo Antunes Lima, Tunde Peto, Niels Wedderkopp, Jakob Grauslund
PURPOSE: To determine associations between physical activity (PA) and myopia in Danish school children and investigate the prevalence of myopia. METHODS: This is a prospective study with longitudinal data on PA in a Danish child cohort. Physical activity (PA) was measured objectively by repeated ActiGraph accelerometer measurement four times with different intervals (1-2.5 years) at the mean ages 9.7, 11.0, 12.9 and 15.4 years. Mean intensity of PA was estimated as counts/minutes, and time spent in sedentary, light, moderate and vigorous PA was summed using defined cut-off points...
July 3, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28671322/factors-related-to-retinal-haemorrhage-in-infants-born-at-high-risk
#9
Qinglan Pu, Ping Li, Huiqin Jiang, Hong Wang, Qiaoyun Zhou, Jia Liu, Wenhua Zhong, Huafei Huang
PURPOSE: This study aims to determine risk factors for retinal haemorrhage (RH) in high-risk infants. METHODS: A total of 3123 cases with high-risk pregnancy and/or neonatal asphyxia 72 hr after delivery were enrolled into this study. Fundus examinations were performed on newborns utilizing a wide-angle imaging system (RetCam III). Retinal haemorrhage (RH) was classified into three grades. Maternal, obstetric and neonatal parameters from high-risk infants with RH were compared with parameters from infants without RH...
July 3, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28671319/neovascular-age-related-macular-degeneration-is-associated-with-cataract-surgery
#10
Jau-Der Ho, Sudha Xirasagar, Li-Ting Kao, Herng-Ching Lin
PURPOSE: This retrospective cohort study examines the association between cataract surgery and neovascular age-related macular degeneration (AMD) during 5-year follow-up using population-based claims data. METHODS: We analysed data sourced from the Taiwan Longitudinal Health Insurance Database 2005. The study included 3465 patients who had undergone cataract operations and did not have a diagnosis of AMD before or on the surgery date (study group), and 10 395 age- and sex-matched comparison patients selected randomly from the remaining patients without an AMD diagnosis before the index date...
July 3, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28661569/effect-of-active-evaluation-on-the-detection-of-negative-dysphotopsia-after-sequential-cataract-surgery-discrepancy-between-incidences-of-unsolicited-and-solicited-complaints
#11
Natalia Y Makhotkina, Marjan D Nijkamp, Tos T J M Berendschot, Bart van den Borne, Rudy M M A Nuijts
PURPOSE: To evaluate the incidence of negative dysphotopsia after sequential cataract surgery. METHODS: Retrospective cohort study. The incidence of negative dysphotopsia was assessed by retrospective reviewing of medical records and interviews with patients between 2 and 4 months after sequential cataract surgery. Inclusion criteria were uncomplicated surgery, postoperative corrected distance visual acuity (CDVA) ≥20/25 Snellen and the absence of ocular comorbidity...
June 29, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28661562/predictors-of-visual-outcome-in-patients-operated-for-craniopharyngioma-a-danish-national-study
#12
Mads Forslund Jacobsen, Ann Sofia Skou Thomsen, Daniella Bach-Holm, Ghazaleh Doroudian, Kamilla Rothe Nissen, Kåre Fugleholm, Lars Poulsgaard, Volkert Siersma, Steffen Heegaard
PURPOSE: Craniopharyngioma often causes visual loss due to the close relation to the anterior visual pathways. This study investigates the incidence and predictors of visual outcomes in patients with craniopharyngioma. METHODS: Data from sixty-six patients who underwent surgery for craniopharyngioma from 2009 to 2013 in Denmark were reviewed. Primary outcomes were visual acuity (VA) and visual field (VF) defects from pre-and postoperative visits. Secondary outcomes were optic nerve atrophy (OA) and papilledema...
June 29, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28661065/prevalence-and-associations-of-epiretinal-membranes-in-the-australian-national-eye-health-survey
#13
LETTER
Stuart Keel, Jing Xie, Joshua Foreman, Peter van Wijngaarden, Hugh R Taylor, Mohamed Dirani
No abstract text is available yet for this article.
June 29, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28653816/validation-of-the-chop-model-for-detecting-severe-retinopathy-of-prematurity-in-a-cohort-of-colorado-infants
#14
LETTER
Emily A McCourt, Brandie Wagner, Jennifer Jung, Erica Wymore, Jasleen Singh, Robert Enzenauer, Rebecca Braverman, Anne Lynch
No abstract text is available yet for this article.
June 27, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28653813/eplerenone-for-chronic-central-serous-chorioretinopathy-a-randomized-controlled-prospective-study
#15
Roy Schwartz, Zohar Habot-Wilner, Michael R Martinez, Amir Nutman, Dafna Goldenberg, Shai Cohen, Shiri Shulman, Hanan Guzner-Gur, Anat Loewenstein, Michaella Goldstein
PURPOSE: To evaluate the efficacy and safety of eplerenone for chronic nonresolving central serous chorioretinopathy (CSC). METHODS: Prospective, double-blind, randomized placebo-controlled study. Nineteen eyes of 17 patients with persistent subretinal fluid (SRF) due to CSC were enrolled and randomized to receive eplerenone 50 mg/day or placebo for 3 months, followed by a 3-month follow-up. The main outcome measure was change in SRF from baseline to 3 months of treatment...
June 27, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28650590/intra-and-interobserver-reproducibility-of-bruch-s-membrane-opening-minimum-rim-width-measurements-with-spectral-domain-optical-coherence-tomography
#16
Alexandre S C Reis, Camila E S Zangalli, Ricardo Y Abe, André L Silva, Jayme R Vianna, José Paulo C Vasconcellos, Vital P Costa
PURPOSE: To investigate the reproducibility of Bruch's membrane opening minimum rim width (BMO-MRW) and retinal nerve fibre layer thickness (RNFLT) measurements using spectral domain optical coherence tomography (SD-OCT). Additionally, to investigate the reproducibility of BMO area measurements and fovea to BMO centre (FoBMO) angle. METHODS: Participants were healthy subjects (n = 30) and patients with glaucoma (n = 26). One eye of each participant was scanned to obtain optic nerve head (24 radial B-scans) and peripapillary (one circular B-scan) images by three independent examiners...
June 26, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28650568/enhanced-functional-properties-of-human-limbal-stem-cells-by-inhibition-of-the-mir-31-fih-1-p21-axis
#17
Zhiping Liu, Weijiao Zhan, Minzhi Zeng, Jinghong Chen, Huyong Zou, Zhiqun Min
OBJECTIVE: On the basis of the functional roles of the embryonic stem cell niche (ESCN) in the human limbal stem cells (LSCs), we proposed to explore the potential roles of microRNAs in regulating the self-renewal and differentiation of LSCs cultured in the ESCN. METHODS: The LSCs were cultured in different media, either in CnT-20 media or in CnT-20 + 20% ES culture supernatant (ESC-CM). The LSCs cultured in ESC-CM were then transfected with microRNA-31 (miR-31) mimic or antago-31...
June 26, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636275/efficacy-of-aflibercept-for-polypoidal-choroidal-vasculopathy-in-caucasians
#18
LETTER
Sanaz Shoja Gharehbagh, Yousif Subhi, Torben Lykke Sørensen
No abstract text is available yet for this article.
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636270/c-reactive-protein-and-progression-of-vision-loss-in-retinitis-pigmentosa
#19
Yusuke Murakami, Yasuhiro Ikeda, Shunji Nakatake, Kohta Fujiwara, Takashi Tachibana, Noriko Yoshida, Shoji Notomi, Toshio Hisatomi, Shigeo Yoshida, Tatsuro Ishibashi, Koh-Hei Sonoda
PURPOSE: Chronic inflammation is involved in retinitis pigmentosa (RP). We demonstrated previously that intraocular inflammatory levels, as measured by slit-lamp ophthalmoscopy or laser flare photometry, are inversely correlated with central visual function in patients with RP. Here, we investigated the relationship between serum high-sensitivity C-reactive protein (hs-CRP) and visual parameters in RP. METHODS: We studied 58 consecutive typical patients with RP <40 years old and 29 age- and gender-matched controls...
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636261/characteristics-of-corneal-biomechanical-responses-detected-by-a-non-contact-scheimpflug-based-tonometer-in-eyes-with-glaucoma
#20
Younhea Jung, Hae-Young L Park, Hee Jung Yang, Chan Kee Park
PURPOSE: To determine the corneal biomechanical properties in eyes with glaucoma using a non-contact Scheimpflug-based tonometer. METHODS: Corneal biomechanical responses were examined using a non-contact Scheimpflug-based tonometer. The tonometer parameters of the normal control group (n = 75) were compared with those of the glaucoma group (n = 136), including an analysis of glaucoma subgroups categorized by visual field loss. RESULTS: After adjusting for potential confounding factors, including the intraocular pressure (IOP), central corneal thickness (CCT), age and axial length, the deformation amplitude was smaller in the glaucoma group (1...
June 21, 2017: Acta Ophthalmologica
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