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Acta Ophthalmologica

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https://www.readbyqxmd.com/read/28926212/treatment-outcomes-of-ziv-aflibercept-for-treatment-na%C3%A3-ve-polypoidal-choroidal-vasculopathy
#1
LETTER
Errol W Chan, Mohab Eldeeb, Vishal Govindhari, Chintan Sarvaiya, Alay Banker, Ahmad Mansour, Jay Chhablani
No abstract text is available yet for this article.
September 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28926210/clinical-relevance-of-retinal-structure-in-children-with-laser-treated-retinopathy-of-prematurity-versus-controls-using-optical-coherence-tomography
#2
Florina Stoica, Adela Chirita-Emandi, Nicoleta Andreescu, Alina Stanciu, Cristian G Zimbru, Maria Puiu
PURPOSE: We aimed to assess the macular anatomy using spectral domain optical coherence tomography (SD-OCT), in children born preterm who had laser-treated retinopathy of prematurity (ROP), and to investigate the relationship between structural changes in macula and visual function. METHODS: Thirty-seven 3-8 years old children were included in the study in two groups: 20 children born preterm [(<34 weeks of gestation, birthweight (BW) <2000 g)] who had laser-treated ROP in the Neonatology Department, Municipal Clinical Emergency Hospital of Timisoara, Romania; and 17 controls (children born at term, without eye disease, matched for age and gender)...
September 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28926202/retinal-dysfunction-characterizes-subtypes-of-dominant-optic-atrophy
#3
Maria Lucia Cascavilla, Vincenzo Parisi, Giacinto Triolo, Lucia Ziccardi, Enrico Borrelli, Antonio Di Renzo, Nicole Balducci, Costanza Lamperti, Stefania Bianchi Marzoli, Fatima Darvizeh, Alfredo A Sadun, Valerio Carelli, Francesco Bandello, Piero Barboni
PURPOSE: To assess preganglionic retinal function using multifocal electroretinogram (mfERG) in patients affected by dominant optic atrophy (DOA) stratified by OPA1 gene mutation. METHODS: Multifocal electroretinogram (mfERG) was recorded in 18 DOA patients (DOA group, 35 eyes) and 25 age-matched healthy subjects (control group, 25 eyes). Patients were stratified in two groups based on gene mutation: missense mutation (DOA-M group, 11 eyes) and mutation causing haploinsufficiency (DOA-H group, 24 eyes)...
September 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28926199/automated-detection-of-diabetic-retinopathy-lesions-on-ultrawidefield-pseudocolour-images
#4
Kang Wang, Chaitra Jayadev, Muneeswar G Nittala, Swetha B Velaga, Chaithanya A Ramachandra, Malavika Bhaskaranand, Sandeep Bhat, Kaushal Solanki, SriniVas R Sadda
PURPOSE: We examined the sensitivity and specificity of an automated algorithm for detecting referral-warranted diabetic retinopathy (DR) on Optos ultrawidefield (UWF) pseudocolour images. METHODS: Patients with diabetes were recruited for UWF imaging. A total of 383 subjects (754 eyes) were enrolled. Nonproliferative DR graded to be moderate or higher on the 5-level International Clinical Diabetic Retinopathy (ICDR) severity scale was considered as grounds for referral...
September 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28926197/epiretinal-membrane-surgery-an-analysis-of-2-step-sequential-or-combined-phacovitrectomy-surgery-on-refraction-and-macular-anatomy-in-a-prospective-trial
#5
Hassan Hamoudi, Ulrik Correll Christensen, Morten La Cour
PURPOSE: To assess the impact of combined phacoemulsification-vitrectomy and sequential surgery for idiopathic epiretinal membrane (ERM) on refractive error (RE) and macular morphology. METHODS: In this prospective clinical trial, we allocated phakic eyes with ERM to (1) cataract surgery and subsequent pars plana vitrectomy (PPV) (CAT group), (2) PPV and subsequent cataract surgery (VIT group) or (3) phaco-vitrectomy (COMBI group). Examinations were at baseline, one month after each surgery, and at 3 months and 12 months of follow-up...
September 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28926193/association-between-cfh-cfb-arms2-serpinf1-vegfr1-and-vegf-polymorphisms-and-anatomical-and-functional-response-to-ranibizumab-treatment-in-neovascular-age-related-macular-degeneration
#6
Estefania Cobos, Sergio Recalde, Jaouad Anter, Maria Hernandez-Sanchez, Carla Barreales, Leticia Olavarrieta, Alicia Valverde, Marta Suarez-Figueroa, Fernando Cruz, Maximino Abraldes, Julian Pérez-Pérez, Patricia Fernández-Robredo, Luis Arias, Alfredo García-Layana
PURPOSE: We sought to determine if specific genetic single nucleotide polymorphisms (SNPs) influence vascular endothelial growth factor inhibition response to ranibizumab in neovascular age-related macular degeneration (AMD). METHODS: A total of 403 Caucasian patients diagnosed with exudative AMD were included. After a three-injection loading phase, a pro re nata regimen was followed. Nine SNPs from six different genes (CFH, CFB, ARMS2, SERPINF1, VEGFR1, VEGF) were genotyped...
September 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28926190/an-8-year-follow-up-of-anti-vascular-endothelial-growth-factor-treatment-with-a-treat-and-extend-modality-for-neovascular-age-related-macular-degeneration
#7
Karina Berg, Anca B Roald, Jesintha Navaratnam, Ragnheiður Bragadóttir
PURPOSE: To investigate long-term visual results of treatment with anti-vascular endothelial growth factor (VEGF) agents for neovascular age-related macular degeneration (nAMD) following a treat-and-extend regimen. METHODS: Retrospective review of 155 patients who initiated treatment with bevacizumab for nAMD in one eye. At the final 8-year visit, 40 patients (26%) remained for follow-up. Mean change in best-corrected visual acuity (BCVA) was calculated compared to baseline values...
September 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28926186/levels-of-beta-trace-protein-in-optic-disc-pit-with-macular-detachment
#8
Karim Makdoumi, Torbjörn K Nilsson, Sven Crafoord
BACKGROUND: To report beta-trace protein (βTP) levels in the subretinal fluid (SRF) of four patients with a macular detachment associated with optic disc pit (ODP). METHODS: Four patients with a serous retinal detachment involving the macula was operated by pars plana vitrectomy (PPV) with C2 F6 gas tamponade and peeling of internal limiting membrane (ILM). Patients with a follow-up period exceeding one year postoperatively were included in the study. The SRF was drained using a fine cannula without laser photocoagulation, and the samples were analysed using particle-enhancing nephelometry...
September 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28921906/outcomes-of-severe-uveitic-glaucoma-treated-with-baerveldt-implant-can-blindness-be-prevented
#9
Annelie N Tan, Michiel F Cornelissen, Carroll A B Webers, Roel J Erckens, Tos T J M Berendschot, Henny J M Beckers
PURPOSE: To evaluate long-term outcomes on efficacy and safety of severe uveitic glaucoma treated with a Baerveldt glaucoma implant (BGI). METHODS: A retrospective study of 47 eyes of 47 patients with uveitic glaucoma treated by a BGI between September 2002 and September 2015. Main outcome measures were intraocular pressure (IOP), number of glaucoma medications, course of the uveitis, visual acuity (VA) and complications. RESULTS: Mean IOP dropped from 30...
September 18, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28887911/deep-capillary-plexus-impairment-in-patients-with-type%C3%A2-1-diabetes-mellitus-with-no-signs-of-diabetic-retinopathy-revealed-using-optical-coherence-tomography-angiography
#10
LETTER
Fabio Scarinci, Fabiana Picconi, Paola Giorno, Barbara Boccassini, Daniele De Geronimo, Monica Varano, Simona Frontoni, Mariacristina Parravano
No abstract text is available yet for this article.
September 9, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28887859/association-between-mode-of-delivery-and-astigmatism-in-preschool-children
#11
Fengyang Liu, Xubo Yang, Angcang Tang, Longqian Liu
PURPOSE: To determine whether mode of delivery has any impact on astigmatism. METHODS: This case-control study was performed in the Department of Ophthalmology in 2015. Exposure was mode of delivery [vaginal delivery (VD) or caesarean section (CS), which here included both elective and emergency CS]. Outcome was astigmatism (≥2.5 D), which was determined by cycloplegic refraction. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were computed to assess the associations between mode of delivery and astigmatism from logistic regression models...
September 9, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28857483/intravitreal-gas-for-symptomatic-vitreomacular-adhesion-a-synthesis-of-the-literature
#12
REVIEW
James E Neffendorf, Andrew R H Simpson, David H W Steel, Riti Desai, Dominic A McHugh, Edward Pringle, Timothy L Jackson
Symptomatic vitreomacular adhesion (sVMA) is defined as visual loss secondary to foveal damage from vitreomacular traction (VMT) and includes isolated VMT, impending macular hole (MH), and full-thickness MH with persisting vitreous attachment. Management options include pars plana vitrectomy (PPV), intravitreal ocriplasmin, intravitreal gas injection or observation. This synthesis of the literature aimed to assess the safety and efficacy of intravitreal gas for sVMA. Articles describing patients with VMT or MH treated with intravitreal expansile gas were selected by systematic literature review using MEDLINE, EMBASE, and the Cochrane Database of Controlled Trials (CENTRAL) up to September 2016...
August 31, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28857463/gastric-bypass-surgery-does-not-increase-the-risk-for-sight-threatening-diabetic-retinopathy
#13
Åsa Morén, Magnus Sundbom, Johan Ottosson, Elisabet Granstam
PURPOSE: To study the occurrence and level of diabetic retinopathy (DRP) before and after planned bariatric surgery and to investigate potential risk factors for deterioration of DRP. METHODS: The Scandinavian Obesity Surgery Registry (SOReg) was used to identify diabetic patients who underwent gastric bypass (GBP) surgery at three centres in Sweden during 2008-2010. Information regarding DRP screening was obtained from ophthalmological patient charts. Patients who had DRP screening before and after GBP surgery were included in the study...
August 31, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28857438/spectacle-use-after-routine-cataract-surgery-a-study-from-the-swedish-national-cataract-register
#14
Daniel B Farhoudi, Anders Behndig, Per Montan, Mats Lundström, Charlotta Zetterström, Maria Kugelberg
PURPOSE: To explore patients' obtaining and use of spectacles after routine cataract surgery. METHODS: The study included 1329 patients who underwent bilateral surgery with the second eye operated during March 2013 at 38 different clinics in Sweden. Five months after the second-eye surgery, patients completed a five-item questionnaire about their spectacle use preoperatively and postoperatively. The responses were linked to data from the registry on multiple variables including postoperative refraction, age and gender...
August 31, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28834375/prominent-regression-of-corneal-deposits-in-fabry-disease-16%C3%A2-years-after-initiation-of-enzyme-replacement-therapy
#15
LETTER
Shizuka Koh, Norio Sakai, Naoyuki Maeda, Kohji Nishida
No abstract text is available yet for this article.
August 22, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28834332/virtual-reality-based-proficiency-test-in-direct-ophthalmoscopy
#16
LETTER
Nanna Jo Borgersen, Ann Sofia Skou Thomsen, Lars Konge, Torben Lykke Sørensen, Yousif Subhi
No abstract text is available yet for this article.
August 22, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28834272/visual-outcomes-in-patients-with-neovascular-age-related-macular-degeneration
#17
LETTER
Colin S Tan, Wei Kiong Ngo, Louis W Lim
No abstract text is available yet for this article.
August 22, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28834252/ganglion-cell-layer-measurements-correlate-with-disease-severity-in-patients-with-alzheimer-s-disease
#18
LETTER
Jurre den Haan, Lisanne J Balk, Frank D Verbraak
No abstract text is available yet for this article.
August 22, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28834250/ocular-findings-in-patients-with-microcephaly-can-suggest-presumed-congenital-zika-virus-infection
#19
Ignasi Jürgens, Amanda Rey
No abstract text is available yet for this article.
August 22, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28834388/dry-eye-disease-and-oxidative-stress
#20
REVIEW
Sophia Seen, Louis Tong
Dry eye, an age-related condition, is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance and tear film instability. Environmental factors are also often implicated in dry eye including exposure to pollutants, ultraviolet (UV) radiation and ozone as well as the chronic use of preserved eyedrops such as in the treatment of glaucoma. These factors increase oxidative stress and ocular surface inflammation. Here, we reviewed the cellular, animal and clinical studies that point to the role of oxidative stress in dry eye disease...
August 21, 2017: Acta Ophthalmologica
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