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Acta Ophthalmologica

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https://www.readbyqxmd.com/read/28636275/efficacy-of-aflibercept-for-polypoidal-choroidal-vasculopathy-in-caucasians
#1
LETTER
Sanaz Shoja Gharehbagh, Yousif Subhi, Torben Lykke Sørensen
No abstract text is available yet for this article.
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636270/c-reactive-protein-and-progression-of-vision-loss-in-retinitis-pigmentosa
#2
Yusuke Murakami, Yasuhiro Ikeda, Shunji Nakatake, Kohta Fujiwara, Takashi Tachibana, Noriko Yoshida, Shoji Notomi, Toshio Hisatomi, Shigeo Yoshida, Tatsuro Ishibashi, Koh-Hei Sonoda
PURPOSE: Chronic inflammation is involved in retinitis pigmentosa (RP). We demonstrated previously that intraocular inflammatory levels, as measured by slit-lamp ophthalmoscopy or laser flare photometry, are inversely correlated with central visual function in patients with RP. Here, we investigated the relationship between serum high-sensitivity C-reactive protein (hs-CRP) and visual parameters in RP. METHODS: We studied 58 consecutive typical patients with RP <40 years old and 29 age- and gender-matched controls...
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636261/characteristics-of-corneal-biomechanical-responses-detected-by-a-non-contact-scheimpflug-based-tonometer-in-eyes-with-glaucoma
#3
Younhea Jung, Hae-Young L Park, Hee Jung Yang, Chan Kee Park
PURPOSE: To determine the corneal biomechanical properties in eyes with glaucoma using a non-contact Scheimpflug-based tonometer. METHODS: Corneal biomechanical responses were examined using a non-contact Scheimpflug-based tonometer. The tonometer parameters of the normal control group (n = 75) were compared with those of the glaucoma group (n = 136), including an analysis of glaucoma subgroups categorized by visual field loss. RESULTS: After adjusting for potential confounding factors, including the intraocular pressure (IOP), central corneal thickness (CCT), age and axial length, the deformation amplitude was smaller in the glaucoma group (1...
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636256/optical-coherence-tomography-angiography-in-choroidal-haemangioma-small-case-series
#4
LETTER
Giuseppe Lo Giudice, Anton Giulio Catania, Alessandro Galan
No abstract text is available yet for this article.
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636255/recombinant-human-serum-albumin-for-corneal-preservation
#5
Mohit Parekh, Hossein Elbadawy, Gianni Salvalaio, Marie-Claude Amoureux, Enzo Di Iorio, Denis Fortier, Diego Ponzin, Stefano Ferrari, Alessandro Ruzza
PURPOSE: To study the performance of a completely synthetic organ culture (OC) preservation system containing recombinant human serum albumin (rHSA) for preservation of human donor corneas. METHODS: Twenty-four paired donor corneas were randomly collected, and one cornea from each donor was preserved in synthetic (experimental) and serum-based media (control). The tissues were assessed at day 0; after 6 days of preservation at room temperature (RT) in Cornea Trans(®) and Cornea Prep II(®) ; after 28 days at 31°C in Cornea Syn(®) [with rHSA] and Cornea Max(®) [with foetal calf serum (FCS)] and; 4-day post deswelling in Cornea Trans(®) and Cornea Jet(®) ...
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636206/retinal-vascular-injuries-and-intravitreal-human-embryonic-stem-cell-derived-haemangioblasts
#6
Jin-Da Wang, Ying An, Jing-Shang Zhang, Xiu-Hua Wan, Wei Zhang, Robert Lanza, Shi-Jiang Lu, Jost B Jonas, Liang Xu
OBJECTIVE: To investigate whether intravitreally applied haemangioblasts (HB) derived from human embryonic stem cells (hESCs) are helpful for the repair of vascular damage caused in animals by an oxygen-induced retinopathy (OIR), by an induced diabetic retinopathy (DR) or by an induced retinal ischaemia with subsequent reperfusion. METHODS: Human embryonic stem cell-derived HBs were transplanted intravitreally into C57BL/6J mice (OIR model), into male Wistar rats with an induced DR and into male Wistar rats undergoing induced retinal ischaemia with subsequent reperfusion...
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636188/selective-laser-trabeculoplasty-as-replacement-therapy-in-medically-controlled-glaucoma-patients
#7
Myrjam De Keyser, Maya De Belder, Jonas De Belder, Veva De Groot
PURPOSE: We examined selective laser trabeculoplasty (SLT) as a replacement therapy for medically controlled open-angle glaucoma (OAG) or ocular hypertensive patients. METHODS: A prospective randomized interventional clinical trial on 143 glaucoma patients. Patients were randomized to either receiving SLT or to the control group that continued on pressure lowering medication. Data were recorded 1 hr, 1 week, 1, 3, 6, 12 and 18 months after SLT. Primary outcome was number of medications at 12 and 18 months while maintaining a predetermined target intraocular pressure (IOP)...
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636169/a-novel-double-nucleotide-variant-in-the-ferritin-l-iron-responsive-element-in-a-finnish-patient-with-hereditary-hyperferritinaemia-cataract-syndrome
#8
Roosa-Maria Mattila, Annele Sainio, Marketta Järveläinen, Juha Pursiheimo, Hannu Järveläinen
PURPOSE: To present a novel Finnish double nucleotide variant in the iron-responsive element (IRE) of the ferritin L-chain gene (FTL) leading to hyperferritinaemia-cataract syndrome (HHCS). METHODS: Genomic DNA extracted from peripheral blood leucocytes and synthetized with three different primers flanking the IRE in the FTL 5'-untranslated region of the FTL was used in polymerase chain reaction (PCR). Thereafter, Sanger sequencing was performed on the 487-bp and 602-bp PCR amplification products with specific primers to reveal FTL IRE mutations...
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636130/microstructural-changes-in-the-fovea-following-autologous-internal-limiting-membrane-transplantation-surgery-for-large-macular-holes
#9
LETTER
Seung Min Lee, Han Jo Kwon, Sung Who Park, Ji Eun Lee, Ik Soo Byon
No abstract text is available yet for this article.
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636126/bilateral-diffuse-uveal-melanocytic-proliferation-case-report-and-literature-review
#10
REVIEW
Kristian Klemp, Jens Folke Kiilgaard, Steffen Heegaard, Tove Nørgaard, Mette Klarskov Andersen, Jan Ulrik Prause
Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a rare paraneoplastic intraocular disease that causes progressive visual loss in patients driven by an IgG factor associated with an underlying malignancy. Characteristic ocular findings include exudative retinal detachment, rapid cataract formation and uveal melanocytic tumours. The awareness and documentation of BDUMP has increased during the past decade, and the increasing amount of data collected demonstrates the effect of treatment with plasmapheresis and the value of diagnostic tools in BDUMP such as genetic and immunologic investigations...
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28636111/microalbuminuria-is-associated-with-increased-choroidal-thickness-in-type-1-diabetes-mellitus-patients-without-diabetic-retinopathy
#11
LETTER
Fernando Korn Malerbi, Caio Vinicius Regatieri, João Roberto de Sa, Paulo Henrique Morales, Michel Eid Farah, Sergio Atala Dib
No abstract text is available yet for this article.
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28635098/venous-loops-a-benign-feature-of-diabetic-retinopathy-or-cause-for-concern
#12
LETTER
Thomas Lee Torp, Tunde Peto, Jakob Grauslund, Søren Leer Blindbaek
No abstract text is available yet for this article.
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28631430/internal-cyclopexy-for-complicated-traumatic-cyclodialysis-cleft
#13
Cong Wang, Xiao-Yan Peng, Qi-Sheng You, Yi Liu, Xiu-Qin Pang, Peng-Fei Zheng, Jost B Jonas
PURPOSE: To assess the surgical and functional outcome of internal direct cyclopexy as therapy of complicated traumatic cyclodialysis. METHODS: The single-centre interventional case-series study included eyes with traumatic cyclodialysis who had consecutively been treated. Internal cyclopexy was performed using double-armed sutures introduced into the eye through the pars plana opposite to the cyclodialysis cleft and which were laid parallel to limbus. Additional procedures included cataract surgery, and pars plana vitrectomy...
June 20, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28631371/aqueous-humour-concentrations-of-tgf-%C3%AE-plgf-and-fgf-1-and-total-retinal-blood-flow-in-patients-with-early-non-proliferative-diabetic-retinopathy
#14
LETTER
Shaolin Du, Lanli Ju, Wenkai Zheng
No abstract text is available yet for this article.
June 20, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28631305/two-years-results-of-small-incision-lenticule-extraction-and-wavefront-guided-laser-in%C3%A2-situ-keratomileusis-for-myopia
#15
Hidenaga Kobashi, Kazutaka Kamiya, Akihito Igarashi, Masahide Takahashi, Kimiya Shimizu
PURPOSE: To compare the 2-years visual and refractive outcomes between small-incision lenticule extraction (SMILE) and wavefront-guided laser in situ keratomileusis (LASIK) in eyes with myopia and myopic astigmatism. METHODS: Our retrospective case-control study examined 30 eyes of 30 patients with the manifest refraction spherical equivalent (MRSE) of -3.71 ± 1.83 dioptres (D) who underwent SMILE and 30 eyes of 30 patients with MRSE of -3.81 ± 1.40 D who underwent wavefront-guided LASIK...
June 20, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28627080/comparison-of-subconjunctival-scarring-after-microincision-vitrectomy-surgery-using-20-23-25-and-27-gauge-systems-in-rabbits
#16
Makoto Gozawa, Yoshihiro Takamura, Seiji Miyake, Kentaro Iwasaki, Shogo Arimura, Yuji Takihara, Masaru Inatani
PURPOSE: To compare subconjunctival scarring after vitrectomy in rabbit eyes using different gauge systems by analysing anterior segment optical coherence tomography (AS-OCT) images and histological sections. METHODS: Vitrectomy using 20-, 23-, 25- and 27-gauge systems was performed for rabbits. Anterior segment optical coherence tomography (AS-OCT) images of the incision sites were obtained before and at day 1, 7 and 1 month after surgery. We measured the thickness of conjunctival epithelium, stroma, Tenon's capsule and total conjunctiva of these three layers, then determined the preservation rates of the borderlines between each layer...
June 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28616896/high-resolution-transbulbar-ultrasonography-helping-differentiate-intracranial-hypertension-in-bilateral-optic-disc-oedema-patients
#17
Qian Chen, Weimin Chen, Min Wang, Xinghuai Sun, Yan Sha, Zhenxin Li, Guohong Tian
PURPOSE: The enlargement of optic nerve sheath diameter (ONSD) has been proven to be related with raised intracranial pressure (ICP). No prospective study has been focused on utilizing retrobulbar ultrasonography in optic disc oedema patient presented to ophthalmologist. METHODS: High-resolution transbulbar ultrasonography was performed in a cohort of patient presented with bilateral optic disc oedema. The subarachnoid space of optic nerve (SAS), ONSD and optic nerve diameter (OND) was measured prior to other ancillaries including lumbar puncture...
June 14, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28616869/a-perfluorobutylpentane-f4h5-based-solution-for-the-removal-of-residual-emulsified-silicone-oil
#18
Yau Kei Chan, Ho Ching Cheng, Jing Wu, Yuk Heng Matthew Tang, San To Chan, David Wong, Ho Cheung Shum
PURPOSE: The emulsification of silicone oil (SO) is associated with many complications. In this study, we investigate a new SO solvent, perfluorobutylpentane (F4H5) with 1% by volume of perfluorinated polyethers-polyethylene glycol-perfluorinated polyethers (PFPE-PEG-PFPE) triblock copolymer, for removing emulsified droplets. METHODS: An in vitro 3D printed model eye chamber was used to evaluate the efficiency of the three test liquids in removing SO droplets, namely saline, F4H5 and F4H5 with surfactant PFPE-PEG-PFPE...
June 14, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28612950/the-paediatric-cataract-register-pecare-an-overview-of-operated-childhood-cataract-in-sweden-and-denmark
#19
Gunilla Magnusson, Birgitte Haargaard, Saima Basit, Anna Lundvall, Alf Nyström, Annika Rosensvärd, Kristina Tornqvist
AIM: To report basic epidemiological data concerning surgically treated childhood cataract in Sweden and Denmark. METHODS: Data were derived from the Paediatric Cataract Register (PECARE), a binational, web-based surgical register representing Sweden and Denmark. All children operated before 8 years of age between 1 January 2007 and 31 December 2013 were included. Age-specific prevalence per 100 000 population was calculated. RESULTS: A total 574 operations in 213 boys (51...
June 14, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28597601/endothelial-alterations-in-712-keratoconus-patients
#20
Susanne Goebels, Timo Eppig, Berthold Seitz, Nòra Szentmàry, Alan Cayless, Achim Langenbucher
PURPOSE: To investigate the effect of the severity of keratoconus on the corneal endothelium using specular microscopy. METHODS: Seven hundred and twelve eyes from the Homburg Keratoconus Center (HKC) database were included in this retrospective study. Corneal endothelium was evaluated using the Tomey EM-3000 specular microscope. Keratoconus-related topographic and tomographic data were obtained from Scheimpflug-based tomography (Oculus Pentacam(®) HR). Eyes were classified into stages 0 (healthy) to 4 (severe keratoconus) according to the Topographic Keratoconus Classification (TKC)...
June 9, 2017: Acta Ophthalmologica
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