Tianyu Zhu, Chunyan Zong, Yongyun Li, Shichong Jia, Hanhan Shi, Hao Tian, Yamin Rao, Xiao Zhang, Shengfang Ge, Xianqun Fan, Yimin Li, Renbing Jia, Shiqiong Xu
PURPOSE: To identify high-risk histopathologic and molecular features of local recurrence, nodal metastasis, distant metastasis (DM) and disease-specific death (DSD) in conjunctival melanoma (CoM). METHODS: Ninety patients with pathologically diagnosed CoM between 2008 and 2023 were enrolled. Immunohistochemistry staining of BRAFV600E , NRASQ61R , CD117, PD-1 and PD-L1 was performed in 65 and 45 patients, respectively. Cox regression and Kaplan-Meier survival analysis were conducted to identify risk factors for local recurrence, nodal metastasis, DM and DSD...
February 29, 2024: Acta Ophthalmologica