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European Annals of Allergy and Clinical Immunology

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https://www.readbyqxmd.com/read/28120607/anaphylaxis-to-hidden-potato-allergens-in-a-peach-and-egg-allergic-boy
#1
M F Martín-Muñoz, A Diaz-Perales, J Cannabal, S Quirce
More than 170 foods have been identified as being potentially allergenic. However, a minority of these foods cause the majority of reactions. Sweets are frequently implicated in allergic reactions in children with cow's milk, egg, nuts or fruits allergy, and they are the most relevant foods investigated as responsible allergens. We report an anaphylactic reaction to candies in an egg and peach allergic boy. We performed a study to identify responsible allergens for the reaction. We investigated hidden egg and peach allergens in the candies, but they were not found...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28120606/a-very-unusual-case-of-food-allergy-between-fpies-and-ige-mediated-food-allergy
#2
S Miceli Sopo, S Monaco, G Cerchiara, G Bersani
Food protein induced enterocolitis syndrome (FPIES) is a food-related gastrointestinal hypersensitivity disorder, probably non-IgE-mediated. Over the years, various diagnostic criteria have been proposed to identify FPIES. In the last few years, there was an increased interest from researchers about FPIES's syndrome, that frequently brought to discover new aspects of this disease. We describe an unusual case of FPIES to egg in a 21-months-old child, because of its clinical characteristics that reflect some aspects of IgE-mediated allergy and other of non IgE-mediated allergy...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28120605/hemophagocytic-lymphohistiocytosis-mimics-many-common-conditions-case-series-and-review-of-literature
#3
A T Akenroye, N Madan, F Mohammadi, J Leider
Introduction. Hemophagocytic lymphohistiocytosis (HLH), a rare but potentially fatal disease, is characterized by excessive immune activation and cytokine release which stimulates bone marrow macrophages to engulf hematopoietic cells. HLH could be secondary to infections: viral, fungal, and bacterial; malignancies and autoimmune diseases. The diagnosis of HLH is usually delayed due to the presence of non-specific symptoms at presentation. This delay contributes to increased mortality. Cases and review. We present the case of 4 patients who presented with subjective fevers and extreme fatigue...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28120604/esophageal-dysfunction-and-immunological-changes-induced-by-grass-sublingual-immunotherapy
#4
C Perales Chordá, E Sáez González, J Martí Garrido, R López Salgueiro, D Hernández Fernández de Rojas
Sublingual immunotherapy frequently causes local oropharyngeal adverse events which are usually of mild severity, and tend to be self-limited and disappear within the first weeks of therapy. The mechanism of action involves changes in the specific humoral response to allergens, with increases in allergen-specific immunoglobulin G4 (IgG4) and blunting of the seasonal increase in allergen-specific IgE. We describe the case of a 25-year-old man diagnosed with grass pollen induced allergic rhinoconjunctivitis, who was treated with a lyophilisate of Phleum pratense by sublingual route...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28120603/high-dose-nebulized-budesonide-is-effective-for-mild-asthma-exacerbations-in-children-under-3-years-of-age
#5
M Saito, Y Kikuchi, A Kawarai Lefor, M Hoshina
Background. High-dose inhaled steroid therapy has been shown to be effective in children and adults with asthma exacerbations. However, few reports are available regarding its efficacy for asthma exacerbations in younger children. Objective. In this study, we administered high-dose nebulized budesonide therapy for mild asthma exacerbations in children < 3 years of age and compared its efficacy and safety with systemic steroid therapy. Methods. This study included children < 3 years old with mild asthma exacerbations...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28120602/ara-h-6-sensitization-in-peanut-allergy-friend-foe-or-innocent-bystander
#6
C Tontini, L Marinangeli, N Maiello, S Abbadessa, D Villalta, L Antonicelli
The clinical role of Ara h 6 sensitization in peanut allergy is a current matter of debate. We investigated the role of Ara h 6 sensitization patterns in a sample of young adults from different Italian cities. Sera of 33 patients with specific IgE against Ara h 6 were selected. According to clinical symptoms upon peanut ingestion, patients were divided into severe reaction (SR) and mild-tolerant (MT) subgroups. While the SR group mainly showed sensitization patterns involving Ara h 2 and other major allergenic components, a previously undescribed association between Ara h 6 and Ara h 9 was found in the MT group...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28120601/hymenoptera-venom-allergy-a-closer-collaboration-is-needed-between-allergists-and-emergency-physicians
#7
A Ciccarelli, C Calabrò, C Imperatore, G Scala
Background. Hymenoptera stings are sometimes fatal in venom-allergic patients. Fatalities mostly occur in previously stung subjects, especially those with a history of systemic reactions, and could be avoided if patients were properly informed of the existence of a prevention strategy for insect stings, referred to an allergy follow-up and prescribed auto-injectable epinephrine and/or venom-specific immunotherapy (VIT). We sought to assess knowledge and awareness of Hymenoptera Venom Allergy (HVA) in a small sample of Emergency Physicians in our geographic area...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28120600/immediate-adverse-reactions-to-intravenous-immunoglobulin-in-children-a-single-center-experience
#8
S Kaba, G Keskindemirci, C Aydogmus, R Siraneci, F Erol Cipe
Intravenous immunoglobulin (IVIG) is commonly used in primary and secondary immunodeficiency diseases as well as autoimmune conditions as immunomodulatator treatment. Immediate adverse events which are generally mild and occur during infusion are seen in 6 hours. Reported immediate adverse events are in a wide range from 1%-40% in pediatric patients. 115 patients who received IVIG (except newborns) were included into this crosssectional study. IVIG was given to patients for primary immunodeficiencies (n=8), ITP (n=65), Kawasaki disease (n=11), secondary immunosupression (n=28), and passive immunization (n=3)...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28120599/parietaria-pollination-duration-myth-or-fact
#9
R Ariano, L Cecchi, S Voltolini, O Quercia, E Scopano, G Ciprandi
Background. Even though the Parietaria pollen season may be rather long, it is commonly thought that Parietaria pollen is a perennial allergen present along the whole year. Objective. This study aimed at investigating the duration of Parietaria pollen season during a 10-year period in Italy, analysing also the annual pollen quantity and the differences among geographical areas. Methods. Pollen count was assessed daily for 10 years. Globally, ten Italian centers measured Parietaria pollen count. Start date, peak date, end date, duration (days), peak value, and seasonal pollen index were evaluated in each center...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28120598/letter-from-the-new-editors
#10
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27852432/febuxostat-hypersensitivity-another-cause-of-dress-syndrome-in-chronic-kidney-disease
#11
E Paschou, E Gavriilaki, G Papaioannou, A Tsompanakou, A Kalaitzoglou, N Sabanis
Febuxostat is a xanthine oxidase inhibitor that during the last years has successfully replaced allopurinol treatment in patients with chronic kidney disease (CKD) and hyperuricemia. Several adverse events have been observed during therapy with febuxostat. DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) syndrome induced by febuxostat has been poorly described, mainly in patient with CKD who previously developed allopurinol hypersensitivity syndrome. DRESS syndrome is characterized by manifold cutaneous reactions and systemic disorders with potential devastating consequences...
November 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27852431/urticarial-vasculitis-in-the-childhood-with-c2-hypocomplementenemia-a-rare-case
#12
Y Keyla Chan, R F J Criado, P R Criado, C D A S Machado, C Speyer
We report a first case of hypocomplementemic urticarial vasculitis of C2 fraction in a child, with cutaneous manifestation only, with no reports in scientific literature.
November 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27852430/use-of-omalizumab-in-the-treatment-of-chronic-urticaria
#13
A S Cordeiro Moreira, M I Rosmaninho Lopes de Soares E Silva, M A Pereira Guilherme, J A da Silva Ferreira, J P Fonseca Moreira da Silva
BACKGROUND: Omalizumab is indicated to treat chronic spontaneous urticaria (CSU) refractory to antihistamines. We aim to describe the experience of our department in the treatment of CSU with omalizumab. MATERIALS AND METHODS: Retrospective review of the clinical records of patients. RESULTS: Six patients (5 females, median age 33 years) treated with omalizumab for a median of 17.5 months were evaluated. All patients had improvement of symptoms after the first dose...
November 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27852429/trends-of-asthma-hospitalization-and-hospital-mortality-in-mainland-portugal
#14
N Santos, A Bugalho de Almeida, A Covas, L Prates, M Morais-Almeida
AIM: To evaluate nationwide asthma hospitalizations and hospital mortality from the year 2000 to 2010. METHODS: Data from the Health Services Central Administration of the Portuguese Ministry of Health on hospital admissions and hospital mortality in the National Health Service in mainland Portugal, from January 1st 2000 to December 31st 2010, were analysed. Cases with bronchial asthma as a main diagnosis were selected. RESULTS: We found a mean frequency of asthma hospitalizations of 2...
November 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27852428/a-pilot-study-to-assess-relationship-between-total-ige-and-95-predictive-decision-points-of-food-specific-ige-concentration
#15
E Yousef, A S Haque
BACKGROUND: False positive test results in children who are tested for food allergies may lead to inappropriate dietary restrictions. OBJECTIVE: The aim of this study was to report our experience with a 3 year-old boy, who presented with "multiple food allergies" and, however, passed the food challenges, and to review our experience regarding management of children with high specific food IgEs with high total IgE. METHODS: Medical records of 16 children with food challenges were reviewed...
November 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27852427/monitoring-the-hospital-management-of-acute-asthma-the-italian-pediatric-network-experience
#16
A G Martelli, R Bianchi, B Boldrighini, M Bosoni, A De Vuono, A Flores D'Arcais, G Gargantini, R Longhi, M T Ortisi, E Racchi, L Parola
BACKGROUND: The Study Group on Accreditation and Quality Improvement of the Italian Society of Pediatrics has developed an observational study about the hospital management of pediatric patients affected by severe asthma, in order to evaluate how the Guidelines for severe asthma in childhood are applied in the daily practice. METHODS: This study included patients between 2 and 17 years, hospitalized or under short intensive observation for acute asthma. The data collection was carried out through the compilation of on-line forms...
November 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27852426/comparing-the-compliance-to-a-short-schedule-of-subcutaneous-immunotherapy-and-to-sublingual-immunotherapy-during-three-years-of-treatment
#17
G Manzotti, G G Riario-Sforza, M Dimatteo, C Scolari, E Makri, C Incorvaia
BACKGROUND: Allergen immunotherapy (AIT) in its two forms of subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) is an effective treatment of respiratory allergy, but is particularly concerned by the issue of compliance. OBJECTIVE: We aimed a real-life study at evaluating the compliance to SLIT and to SCIT administered by a short-course of four injections during a 3-year period of observation. METHODS: A group of 145 patients (79 males, 66 females, age ranging from 14 to 69 years), suffering from pollen-induced rhino-conjunctivitis with or without asthma, were included in the study...
November 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27852425/comano-thermal-water-inhalations-in-the-treatment-of-allergic-rhinitis-preliminary-results
#18
G Ciprandi, M Cristofolini, E Mira
BACKGROUND: Comano thermal water, well known for its activity in the treatment of dermatological diseases, has been successfully employed in the treatment of upper airways disorders. OBJECTIVE: The present preliminary study aimed to evaluate whether Comano thermal water may be able to improve nasal symptoms severity in patients with allergic rhinitis (AR). METHODS: 30 AR patients were enrolled (mean age 40.9 years; 13 males) and treated with inhalation of Comano thermal water for 15 days...
November 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27852424/hypersensitivity-to-beta-lactam-antibiotics-a-three-year-study
#19
I Mota, Â Gaspar, M Chambel, S Piedade, M Morais-Almeida
BACKGROUND: Beta-lactams antibiotics (BL) are the most frequent elicitors of allergic drug reactions. The aim of our study was to characterize the patients referred with suspected hypersensitivity (HS) to BL. METHODS: Over a three-year period (2011-2013), a total of 234 adult and paediatric patients (pts) with suspected HS to BL were investigated according to the European Network for Drug Allergy guidelines. RESULTS: HS to BL was confirmed in 43 pts (18%), without differences between adult and paediatric pts; anaphylaxis was reported by 20 pts...
November 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27608479/self-reported-hair-loss-in-patients-with-chronic-spontaneous-urticaria-treated-with-omalizumab-an-under-reported-transient-side-effect
#20
G N Konstantinou, A G Chioti, M Daniilidis
Omalizumab has been recently approved for treating patients with refractory to H1- antihistamines chronic spontaneous urticaria (CSU). Although hair loss is listed among omalizumab side effects, there are no available data to estimate its frequency. We describe for the first time hair loss as a side effect associated with omalizumab administration in three women, 38, 62 and 70 years old, suffering from refractory to H1-antihistamines CSU. This information was retrieved from their Chronic Urticaria Quality of Life Questionnaires...
September 2016: European Annals of Allergy and Clinical Immunology
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