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Brain Stimulation

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https://www.readbyqxmd.com/read/28501325/a-role-for-nmdar-dependent-cerebellar-plasticity-in-adaptive-control-of-saccades-in-humans
#1
S Colnaghi, P Colagiorgio, M Versino, G Koch, E D'Angelo, S Ramat
BACKGROUND: Saccade pulse amplitude adaptation is mediated by the dorsal cerebellar vermis and fastigial nucleus. Long-term depression at the parallel fibre-Purkinjie cell synapses has been suggested to provide a cellular mechanism for the corresponding learning process. The mechanisms and sites of this plasticity, however, are still debated. OBJECTIVE: To test the role of cerebellar plasticity phenomena on adaptive saccade control. METHODS: We evaluated the effect of continuous theta burst stimulation (cTBS) over the posterior vermis on saccade amplitude adaptation and spontaneous recovery of the initial response...
May 5, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28522346/seeing-in-the-dark-phosphene-thresholds-with-eyes-open-versus-closed-in-the-absence-of-visual-inputs
#2
T A de Graaf, F Duecker, Y Stankevich, S Ten Oever, A T Sack
BACKGROUND: Voluntarily opening or closing our eyes results in fundamentally different input patterns and expectancies. Yet it remains unclear how our brains and visual systems adapt to these ocular states. OBJECTIVE/HYPOTHESIS: We here used transcranial magnetic stimulation (TMS) to probe the excitability of the human visual system with eyes open or closed, in the complete absence of visual inputs. METHODS: Combining Bayesian staircase procedures with computer control of TMS pulse intensity allowed interleaved determination of phosphene thresholds (PT) in both conditions...
May 3, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28528736/on-the-effectiveness-of-event-related-beta-tacs-on-episodic-memory-formation-and-motor-cortex-excitability
#3
Verena Braun, Rodika Sokoliuk, Simon Hanslmayr
BACKGROUND: Transcranial alternating current stimulation (tACS) is widely used to entrain or modulate brain oscillations in order to investigate causal relationships between oscillations and cognition. OBJECTIVE: In a series of experiments we here addressed the question of whether event-related, transient tACS in the beta frequency range can be used to entrain beta oscillations in two different domains: episodic memory formation and motor cortex excitability. METHODS: In experiments 1 and 2, 72 healthy human participants engaged in an incidental encoding task of verbal and non-verbal material while receiving tACS to the left and right inferior frontal gyrus (IFG) at 6...
April 30, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28506878/pain-motor-integration-in-the-primary-motor-cortex-in-parkinson-s-disease
#4
A Suppa, C Leone, F Di Stasio, L Marsili, A Di Santo, A Biasiotta, S La Cesa, A Truini, G Cruccu, A Berardelli
BACKGROUND: In Parkinson's disease (PD), the influence of chronic pain on motor features has never been investigated. We have recently designed a technique that combines nociceptive system activation by laser stimuli and primary motor cortex (M1) activation through transcranial magnetic stimulation (TMS), in a laser-paired associative stimulation design (Laser-PAS). In controls, Laser-PAS induces long-term changes in motor evoked potentials reflecting M1 long-term potentiation-like plasticity, arising from pain-motor integration...
April 30, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28487047/anodal-and-cathodal-electrical-stimulation-over-v5-improves-motion-perception-by-signal-enhancement-and-noise-reduction
#5
Luca Battaglini, Stefano Noventa, Clara Casco
BACKGROUND: The effect that transcranial direct current stimulation (tDCS) has on discrimination of coherent motion (CM) signals in a field of randomly moving dots (noise) can be accounted for by both noise reduction and signal enhancement. OBJECTIVE: To distinguish between noise reduction and signal enhancement, we monitored the discrimination of the correct CM direction as a function of the coherence level (using the psychophysical method of constant stimuli)...
April 28, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28462881/safety-and-efficacy-of-long-term-home-treatment-with-transcranial-direct-current-stimulation-tdcs-in-a-case-of-multimodal-hallucinations
#6
LETTER
Tobias Schwippel, Barbara Wasserka, Andreas J Fallgatter, Christian Plewnia
No abstract text is available yet for this article.
April 20, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28457836/imaging-of-current-flow-in-the-human-head-during-transcranial-electrical-therapy
#7
A K Kasinadhuni, A Indahlastari, M Chauhan, Michael Schär, T H Mareci, R J Sadleir
BACKGROUND: It has been assumed that effects caused by tDCS or tACS neuromodulation are due to electric current flow within brain structures. However, to date, direct current density distributions in the brains of human subjects have not been measured. Instead computational models of tDCS or tACS have been used to predict electric current and field distributions for dosimetry and mechanism analysis purposes. OBJECTIVE/HYPOTHESIS: We present the first in vivo images of electric current density distributions within the brain in four subjects undergoing transcranial electrical stimulation...
April 20, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28455217/subthalamic-nucleus-deep-brain-stimulation-for-the-treatment-of-secondary-dystonia-a-case-series-and-review-of-literature
#8
LETTER
Jason Margolesky, Nathan Schoen, Walter Jermakowicz, Samir Sur, Iahn Cajigas, Carlos Singer, Jonathan Jagid, Corneliu C Luca
No abstract text is available yet for this article.
April 18, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28438544/reply-to-the-letter-to-the-editor-on-no-modulatory-effects-by-tsms-when-delivered-during-a-cognitive-task
#9
LETTER
Marco Kufner, Sabrina Brückner, Thomas Kammer
No abstract text is available yet for this article.
April 17, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28461068/coil-optimisation-for-transcranial-magnetic-stimulation-in-realistic-head-geometry
#10
Lari M Koponen, Jaakko O Nieminen, Tuomas P Mutanen, Matti Stenroos, Risto J Ilmoniemi
BACKGROUND: Transcranial magnetic stimulation (TMS) allows focal, non-invasive stimulation of the cortex. A TMS pulse is inherently weakly coupled to the cortex; thus, magnetic stimulation requires both high current and high voltage to reach sufficient intensity. These requirements limit, for example, the maximum repetition rate and the maximum number of consecutive pulses with the same coil due to the rise of its temperature. OBJECTIVE: To develop methods to optimise, design, and manufacture energy-efficient TMS coils in realistic head geometry with an arbitrary overall coil shape...
April 15, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28457837/cost-effectiveness-of-deep-brain-stimulation-versus-treatment-as-usual-for-obsessive-compulsive-disorder
#11
Pieter Ooms, Matthijs Blankers, Martijn Figee, Isidoor O Bergfeld, Pepijn van den Munckhof, P Richard Schuurman, Damiaan Denys
BACKGROUND: Deep Brain Stimulation (DBS) is effective for obsessive-compulsive disorder (OCD), but requires expensive medical procedures. To date, no study has examined the cost-effectiveness of DBS for OCD. OBJECTIVE: To perform the first economic evaluation of DBS for therapy refractory OCD. METHODS: We conducted a 2-year prospective, open cost-effectiveness study, comparing DBS (n = 17) with treatment as usual (TAU) (n = 11), with cost per Quality-Adjusted-Life-Year (QALY) as outcome measure...
April 13, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28438545/no-modulatory-effects-by-tsms-when-delivered-during-a-cognitive-task
#12
LETTER
Guglielmo Foffani, Michele Dileone
No abstract text is available yet for this article.
April 13, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28420582/are-current-flow-models-for-transcranial-electrical-stimulation-fit-for-purpose
#13
LETTER
Sven Bestmann, Nick Ward
No abstract text is available yet for this article.
April 10, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28420581/response-variability-of-different-anodal-transcranial-direct-current-stimulation-intensities-across-multiple-sessions
#14
Claudia Ammann, Martin A Lindquist, Pablo A Celnik
BACKGROUND: It is well known that transcranial direct current stimulation (tDCS) is capable of modulating corticomotor excitability. However, a source of growing concern has been the observed inter- and intra-individual variability of tDCS-responses. Recent studies have assessed whether individuals respond in a predictable manner across repeated sessions of anodal tDCS (atDCS). The findings of these investigations have been inconsistent, and their methods have some limitations (i.e. lack of sham condition or testing only one tDCS intensity)...
April 10, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28462882/first-clinical-use-of-epidural-stimulation-in-catatonia
#15
LETTER
Emmanuel Stip, Paul Lespérance, Olivier Farmer, Marie-Pierre Fournier-Gosselin
No abstract text is available yet for this article.
April 4, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28438543/modulation-of-motor-cortex-excitability-predicts-antidepressant-response-to-prefrontal-cortex-repetitive-transcranial-magnetic-stimulation
#16
Albino J Oliveira-Maia, Daniel Press, Alvaro Pascual-Leone
BACKGROUND: Repetitive transcranial magnetic stimulation (rTMS) targeting the left dorsolateral prefrontal cortex (DLPFC) is a treatment option for patients with medication-resistant major depressive disorder (MDD). However, antidepressant response is variable and there are currently no response predictors with sufficient accuracy for clinical use. OBJECTIVE: We report on results of an observational open-label study to determine whether the modulatory effect of 10 Hz motor cortex (MC) rTMS is predictive of the antidepressant effect of 10 Hz DLPFC rTMS...
March 31, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28416160/the-antidepressant-like-effect-of-tdcs-in-mice-a-behavioral-and-neurobiological-characterization
#17
Tanat Peanlikhit, Vincent Van Waes, Solène Pedron, Pierre-Yves Risold, Emmanuel Haffen, Adeline Etiévant, Julie Monnin
BACKGROUND: Transcranial direct current stimulation (tDCS) is a non-invasive method increasingly popular for the treatment of several brain disorders, such as major depression. Despite great enthusiasm and promising results, some studies report discrepant findings and no consensus exists for the clinical use of tDCS. OBJECTIVE: The present study aims to (i) determine the most effective stimulation parameters to optimize antidepressant-like effect of tDCS in the forced-swim test in mice and (ii) identify brain regions recruited by tDCS and possibly involved in its behavioral effect using Fos immunohistochemistry...
March 29, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28392373/persistent-blood-glucose-reduction-upon-repeated-transcranial-electric-stimulation-in-men
#18
Alina Kistenmacher, Sebastian Manneck, Ewelina K Wardzinski, Jan C Martens, Georg Gohla, Uwe H Melchert, Kamila Jauch-Chara, Kerstin M Oltmanns
BACKGROUND: Transcranial direct current stimulation (tDCS) of the human brain increases systemic glucose tolerance. OBJECTIVE/HYPOTHESIS: To investigate whether this effect persists after one week of repeated stimulation. Because systemic glucose uptake relates to brain energy homeostasis, we concomitantly measured cerebral high-energy phosphate metabolites. METHODS: In a sham-controlled crossover design, 14 healthy men were tested under daily anodal tDCS vs...
March 25, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28528737/brainruler-a-free-open-access-tool-for-calculating-scalp-to-cortex-distance
#19
LETTER
Philipp M Summers, Colleen A Hanlon
No abstract text is available yet for this article.
March 23, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28404455/modulation-of-itbs-after-effects-via-concurrent-directional-tdcs-a-proof-of-principle-study
#20
Sara Tremblay, Ricci Hannah, Vishal Rawji, John C Rothwell
BACKGROUND: Polarising currents can modulate membrane potentials in animals, affecting the after-effect of theta burst stimulation (TBS) on synaptic strength. OBJECTIVE: We examined whether a similar phenomenon could also be observed in human motor cortex (M1) using transcranial direct current stimulation (TDCS) during monophasic intermittent TBS (iTBS). METHODS: TDCS was applied during posterior-anterior iTBS using three different conditions: posterior-anterior TDCS (anode 3...
March 23, 2017: Brain Stimulation
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