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Brain Stimulation

Aaron Kortteenniemi, Soili M Lehto, Amir-Homayoun Javadi
No abstract text is available yet for this article.
November 3, 2018: Brain Stimulation
Robert A Morrison, Daniel R Hulsey, Katherine S Adcock, Robert L Rennaker, Michael P Kilgard, Seth A Hays
BACKGROUND: Vagus nerve stimulation (VNS) paired with forelimb motor training enhances reorganization of movement representations in the motor cortex. Previous studies have shown an inverted-U relationship between VNS intensity and plasticity in other brain areas, such that moderate intensity VNS yields greater cortical plasticity than low or high intensity VNS. However, the relationship between VNS intensity and plasticity in the motor cortex is unknown. OBJECTIVE: In this study we sought to test the hypothesis that VNS intensity exhibits an inverted-U relationship with the degree of motor cortex plasticity in rats...
November 3, 2018: Brain Stimulation
Aprinda Indahlastari, Alejandro Albizu, Nicole R Nissim, Kelsey R Traeger, Andrew O'Shea, Adam J Woods
BACKGROUND: Inaccurate electrode placement and electrode drift during a transcranial electrical stimulation (tES) session have been shown to alter predicted field distributions in the brain and thus may contribute to a large variation in tES study outcomes. Currently, there is no objective and independent measure to quantify electrode placement accuracy/drift in tES clinical studies. OBJECTIVE/HYPOTHESIS: We proposed and tested novel methods to quantify accurate and consistent electrode placements in tES using models generated from a 3D scanner...
October 28, 2018: Brain Stimulation
Cédric Lenoir, André Mouraux
No abstract text is available yet for this article.
October 28, 2018: Brain Stimulation
Fatemeh Khademi, Vladislav Royter, Alireza Gharabaghi
BACKGROUND: Intrinsic motor cortex activity modifies corticospinal excitability (CSE) in accordance with both oscillatory power fluctuations and phase-specific modulation along the oscillatory beta cycle, particularly in the 16-17 Hz frequency bin. OBJECTIVE: To determine the magnitude of CSE and the relevance of stimulation timing for input gain mediated by either oscillatory power or phase. METHODS: We applied single-pulse transcranial magnetic stimulation (TMS) over the primary motor cortex of healthy subjects at rest during electroencephalography recordings...
October 26, 2018: Brain Stimulation
Águida Foerster, Fatemeh Yavari, Leila Farnad, Asif Jamil, Walter Paulus, Michael A Nitsche, Min-Fang Kuo
BACKGROUND: For effects of transcranial direct current stimulation (tDCS), electrical field distribution and coverage of the target areas play a decisive role. METHODS: We explored the effect of different angle-orientations of tDCS electrodes applied over the upper limb motor cortex (M1) on motor cortex excitability in healthy volunteers. Sixteen individuals received 1 mA anodal or cathodal tDCS through 35 cm2 electrodes over M1 for 15 min. Transcranial magnetic stimulation was used to examine tDCS-generated cortical excitability effects...
October 25, 2018: Brain Stimulation
Koichi Hagiwara, Jean Isnard, Roland Peyron, Luis Garcia-Larrea
No abstract text is available yet for this article.
October 24, 2018: Brain Stimulation
Silvia Casarotto, Francesco Turco, Angela Comanducci, Alessio Perretti, Giorgio Marotta, Gianni Pezzoli, Mario Rosanova, Ioannis U Isaias
BACKGROUND: Cortical dysfunctioning significantly contributes to the pathogenesis of motor symptoms in Parkinson's disease (PD). OBJECTIVE: We aimed at testing whether an acute levodopa administration has measurable and specific cortical effects possibly related to striatal dopaminergic deficit. METHODS: In thirteen PD patients, we measured the electroencephalographic responses to transcranial magnetic stimulation (TMS/EEG) of the supplementary motor area and superior parietal lobule (n = 8) before and after an acute intake of levodopa...
October 23, 2018: Brain Stimulation
Wan-Yu Hsu, Theodore P Zanto, Adam Gazzaley
BACKGROUND: We have previously demonstrated that transcranial alternating current stimulation (tACS) can generate positive effects on multitasking performance and associated neurophysiological measures when it is applied with anti-phase theta band stimulation across bilateral prefrontal cortex (PFC) and a short (1-min) inter-session interval (ISI). However, it is unclear how altering the phase of stimulation and the duration of the ISI might impact positive tACS effects. Here, we investigated the role of tACS parameters in engendering performance improvements by manipulating these two stimulation parameters (i...
October 23, 2018: Brain Stimulation
Francesco Di Lorenzo, Caterina Motta, Sonia Bonnì, Nicola Biagio Mercuri, Carlo Caltagirone, Alessandro Martorana, Giacomo Koch
BACKGROUND: Alzheimer's disease (AD) is characterized by a primary impairment of long-term declarative memory caused by deposition of misfolded protein aggregates. Experimental studies showed that AD neuropathological alterations impair synaptic plasticity and memory performance. Transcranial Magnetic Stimulation protocols have been recently introduced to investigate altered mechanisms of cortical plasticity in AD patients. AIM: To investigate relationship between Long-Term Potentiation (LTP)-like cortical plasticity and patients' neuropsychological performance...
October 19, 2018: Brain Stimulation
Samuel Zibman, Edan Daniel, Uri Alyagon, Amit Etkin, Abraham Zangen
BACKGROUND: As advances in neuroimaging further our understanding of the brain's functional connectivity, neuropsychology has moved away from a regional approach of attributing behavior to a specific region towards a network approach, attributing behavior to interconnected regions. A prime example of this is the suggested relevance of frontal asymmetry of the lateral prefrontal cortex (LPFC) in emotional processing. Yet, while neuroimaging defines relevant networks, it can only establish correlations and not causality...
October 18, 2018: Brain Stimulation
Lipeng Ning, Nikos Makris, Joan A Camprodon, Yogesh Rathi
BACKGROUND: Transcranial magnetic stimulation (TMS) is a noninvasive neuromodulation technique with therapeutic applications for the treatment of major depressive disorder (MDD). The standard protocol uses high frequency stimulation over the left dorsolateral prefrontal cortex (DLPFC) identified in a heuristic manner leading to moderate clinical efficacy. A proposed strategy to increase the anatomical precision in targeting, based on resting-state functional MRI (rsfMRI), identifies the subregion within the DLPFC having the strongest anticorrelated functional connectivity with the subgenual cortex (SGC) for each individual subject...
October 13, 2018: Brain Stimulation
William J Huffman, Saraswathi Subramaniyan, Ramona M Rodriguiz, William C Wetsel, Warren M Grill, Niccolò Terrando
BACKGROUND: The vagus nerve is involved in regulating immunity and resolving inflammation. Current strategies aimed at modulating neuroinflammation and cognitive decline, in many cases, are limited and ineffective. OBJECTIVE: We sought to develop a minimally invasive, targeted, vagus nerve stimulation approach (pVNS), and we tested its efficacy with respect to microglial activation and amelioration of cognitive dysfunction following lipopolysaccharide (LPS) endotoxemia in mice...
October 9, 2018: Brain Stimulation
T Rudroff, F Proessl, J Kamholz, L L Ponto
No abstract text is available yet for this article.
October 6, 2018: Brain Stimulation
Ulrich Palm, Stephan Goerigk, Beatrice Kirsch, Leonie Bäumler, Nina Sarubin, Alkomiet Hasan, Andre R Brunoni, Frank Padberg
No abstract text is available yet for this article.
October 3, 2018: Brain Stimulation
Suhan Senova, Gonçalo Cotovio, Alvaro Pascual-Leone, Albino J Oliveira-Maia
BACKGROUND: The therapeutic options for treatment-resistant depression (TRD) encompass a range of neuromodulatory techniques, including repetitive transcranial magnetic stimulation (rTMS). While rTMS is safe and has documented short-term efficacy, durability of antidepressant effects is poorly established. OBJECTIVE: Assess existing evidence regarding durability of rTMS-induced antidepressant response. METHODS: We performed a systematic review of studies reporting antidepressant outcome measures collected three or more months after the end of an induction course of rTMS for depression...
October 2, 2018: Brain Stimulation
Mark van de Ruit, Tom Pearson, Michael J Grey
No abstract text is available yet for this article.
October 2, 2018: Brain Stimulation
J P Lindenmayer, Mila Kirstie C Kulsa, Tania Sultana, Amandeep Kaur, Ran Yang, Isidora Ljuri, Benedicto Parker, Anzalee Khan
BACKGROUND: Transcranial direct-current stimulation (tDCS), a non-invasive neurostimulation treatment, has been reported in a number of sham-controlled studies to show significant improvements in treatment-resistant auditory hallucinations in schizophrenia patients, primarily in ambulatory and higher-functioning patients, but little is known of the effects of tDCS on hospitalized, low-functioning inpatients. OBJECTIVE/HYPOTHESIS: The purpose of this study was to examine the efficacy and safety of tDCS for auditory hallucinations in hospitalized ultra-treatment-resistant schizophrenia (TRS) and to evaluate the effects of tDCS on cognitive functions...
October 2, 2018: Brain Stimulation
Julius Fridriksson, Alexandra Basilakos, Brielle C Stark, Chris Rorden, Jordan Elm, Michelle Gottfried, Mark S George, Souvik Sen, Leonardo Bonilha
No abstract text is available yet for this article.
September 29, 2018: Brain Stimulation
Pietro Sarasso, Marco Ninghetto, Adriana Salatino, Irene Ronga, Alessandro Bongiardina, Igor Iarrobino, Marco Neppi-Modona, Raffaella Ricci
No abstract text is available yet for this article.
September 29, 2018: Brain Stimulation
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