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Brain Stimulation

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https://www.readbyqxmd.com/read/28330592/61-of-unmedicated-treatment-resistant-depression-patients-who-did-not-respond-to-acute-tms-treatment-responded-after-four-weeks-of-twice-weekly-deep-tms-in-the-brainsway-pivotal-trial
#1
Agustin G Yip, Mark S George, Aron Tendler, Yiftach Roth, Abraham Zangen, Linda L Carpenter
BACKGROUND: An acute course of dTMS typically involves treatments delivered 5 days a week, for 4 weeks. Should more treatments be given if the patient has not responded? Data are needed to inform decisions about the best next steps for acute non-responders. OBJECTIVE: To characterize response among acute-phase non-responders in a randomized controlled trial of deep repetitive transcranial magnetic stimulation (dTMS) monotherapy for medication-resistant depression...
March 10, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28302459/no-modulatory-effects-by-transcranial-static-magnetic-field-stimulation-of-human-motor-and-somatosensory-cortex
#2
Marco Kufner, Sabrina Brückner, Thomas Kammer
BACKGROUND: Recently, it was reported that the application of a static magnetic field by placing a strong permanent magnet over the scalp for 10 min led to an inhibition of motor cortex excitability for at least 6 min after removing the magnet. When placing the magnet over the somatosensory cortex, a similar inhibitory after effect could be observed as well. OBJECTIVE: Our aim was to replicate the inhibitory effects of transcranial static magnetic field stimulation in the motor and somatosensory system...
March 6, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28285889/influence-of-inter-train-interval-on-the-plastic-effects-of-rtms
#3
Robin F H Cash, Aisha Dar, Jeanette Hui, Leo De Ruiter, Julianne Baarbé, Peter Fettes, Sarah Peters, Paul B Fitzgerald, Jonathan Downar, Robert Chen
BACKGROUND: High frequency repetitive transcranial magnetic stimulation (rTMS) elicits plastic effects in excitatory and inhibitory circuits. Inter-train intervals (ITI) were initially incorporated into rTMS paradigms to avoid overheating and for safety considerations. Recent studies have shown that inclusion of ITI, as opposed to continuous stimulation, is essential for eliciting excitatory effects, but the optimal ITI remains unknown. Moreover, if ITI duration has no effect, it may be possible to substantially reduce treatment time for rTMS...
March 2, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28330632/female-sex-hormones-modulate-the-response-to-low-frequency-rtms-in-the-human-motor-cortex
#4
LETTER
Lynn M Rogers, Yasin Y Dhaher
No abstract text is available yet for this article.
March 1, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28283370/reduced-multimodal-integration-of-memory-features-following-continuous-theta-burst-stimulation-of-angular-gyrus
#5
Yasemin Yazar, Zara M Bergström, Jon S Simons
BACKGROUND: Lesions of the angular gyrus (AnG) region of human parietal cortex do not cause amnesia, but appear to be associated with reduction in the ability to consciously experience the reliving of previous events. OBJECTIVES/HYPOTHESIS: We used continuous theta burst stimulation to test the hypothesis that the cognitive mechanism implicated in this memory deficit might be the integration of retrieved sensory event features into a coherent multimodal memory representation...
March 1, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28284918/intracortical-microstimulation-differentially-activates-cortical-layers-based-on-stimulation-depth
#6
Mathias Benjamin Voigt, Peter Hubka, Andrej Kral
BACKGROUND: Intracortical microstimulation is one of the most common techniques to causally interfere with neuronal processing, but neuronal recordings spanning the whole cortical depth during stimulation are exceptionally rare. OBJECTIVE/HYPOTHESIS: Here we combined layer-specific intracortical microstimulation with extracellular recordings on the same shank of a linear multi-electrode array to study the effects of electrical stimulation in different cortical depths on intracortical processing in the auditory cortex in vivo...
February 27, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28279642/low-intensity-400%C3%A2-mw-cm-2-500%C3%A2-khz-pulsed-transcranial-ultrasound-preconditioning-may-mitigate-focal-cerebral-ischemia-in-rats
#7
Hangdao Li, Junfeng Sun, Daqu Zhang, Daryl Omire-Mayor, Peter A Lewin, Shanbao Tong
BACKGROUND: Preconditioning methods, which could increase tolerance of brain to subsequent ischemic injuries with a small dose of non-injury stimuli, have gained attention. Capitalizing on noninvasiveness and safety of ultrasound modality, the pulsed transcranial ultrasound stimulation (pTUS) approach may provide a novel treatment for patients with high risk of stroke. OBJECTIVE: This study's goal was to investigate whether the risk of stroke could be minimized or eliminated by prior exposure to low-intensity, pulsed transcranial ultrasound stimulation (pTUS)...
February 27, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28279641/safety-and-tolerability-of-transcranial-direct-current-stimulation-to-stroke-patients-a-phase-i-current-escalation-study
#8
Pratik Y Chhatbar, Rong Chen, Rachael Deardorff, Blair Dellenbach, Steven A Kautz, Mark S George, Wuwei Feng
BACKGROUND AND OBJECTIVE: A prior meta-analysis revealed that higher doses of transcranial direct current stimulation (tDCS) have a better post-stroke upper-extremity motor recovery. While this finding suggests that currents greater than the typically used 2 mA may be more efficacious, the safety and tolerability of higher currents have not been assessed in stroke patients. We aim to assess the safety and tolerability of single session of up to 4 mA in stroke patients. METHODS: We adapted a traditional 3 + 3 study design with a current escalation schedule of 1»2»2...
February 27, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28298263/a-proof-of-principle-simulation-for-closed-loop-control-based-on-preexisting-experimental-thalamic-dbs-enhanced-instrumental-learning
#9
Ching-Fu Wang, Shih-Hung Yang, Sheng-Huang Lin, Po-Chuan Chen, Yu-Chun Lo, Han-Chi Pan, Hsin-Yi Lai, Lun-De Liao, Hui-Ching Lin, Hsu-Yan Chen, Wei-Chen Huang, Wun-Jhu Huang, You-Yin Chen
Deep brain stimulation (DBS) has been applied as an effective therapy for treating Parkinson's disease or essential tremor. Several open-loop DBS control strategies have been developed for clinical experiments, but they are limited by short battery life and inefficient therapy. Therefore, many closed-loop DBS control systems have been designed to tackle these problems by automatically adjusting the stimulation parameters via feedback from neural signals, which has been reported to reduce the power consumption...
February 24, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28274722/effects-of-vestibular-rehabilitation-combined-with-transcranial-cerebellar-direct-current-stimulation-in-patients-with-chronic-dizziness-an-exploratory-study
#10
Satoko Koganemaru, Fumiyuki Goto, Miki Arai, Keitaro Toshikuni, Makoto Hosoya, Takeshi Wakabayashi, Nobuko Yamamoto, Shujiro Minami, Satoshi Ikeda, Katsunori Ikoma, Tatsuya Mima
BACKGROUND: Vestibular rehabilitation is useful to alleviate chronic dizziness in patients with vestibular dysfunction. It aims to induce neuronal plasticity in the central nervous system (especially in the cerebellum) to promote vestibular compensation. Transcranial cerebellar direct current stimulation (tcDCS) reportedly enhances cerebellar function. OBJECTIVE/HYPOTHESIS: We investigated whether vestibular rehabilitation partially combined with tcDCS is superior to the use of rehabilitation alone for the alleviation of dizziness...
February 24, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28274721/role-of-%C3%AE-endorphin-in-pain-relief-following-high-rate-repetitive-transcranial-magnetic-stimulation-in-migraine
#11
Usha Kant Misra, Jayantee Kalita, Gyanesh Tripathi, Sanjeev Kumar Bhoi
BACKGROUND: In migraine, high rate repetitive transcranial magnetic stimulation (rTMS) has been reported to be effective, and β endorphin (BE) may have a role in headache relief. OBJECTIVE: To report the role of BE and its μ (MOR) and δ opioid receptors (DOR) in headache relief following high rate rTMS in migraine. METHODS: Ninety-three migraine patients having more than 4 attacks per month were included. 10 Hz rTMS (600 pulses in 10 trains) was delivered to left motor cortex; 3 sessions to 24 (group 1), 1 session to 22 (group II) and sham stimulation to 47 patients (group III)...
February 24, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28330593/electroconvulsive-therapy-in-a-patient-with-left-ventricular-assist-device-following-deliberate-disconnection-of-the-device-driveline
#12
LETTER
M Augustin, C S Bruells, A Moza, B Gillmann, L Mevissen, M Grözinger
No abstract text is available yet for this article.
February 16, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28259543/repeated-stimulation-of-the-posterior-parietal-cortex-in-patients-in-minimally-conscious-state-a-sham-controlled-randomized-clinical-trial
#13
LETTER
Wangshan Huang, Sarah Wannez, Felipe Fregni, Xiaohua Hu, Shan Jing, Geraldine Martens, Minhui He, Haibo Di, Steven Laureys, Aurore Thibaut
No abstract text is available yet for this article.
February 16, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28254363/the-human-globus-pallidus-internus-is-sensitive-to-rewards-evidence-from-intracerebral-recordings
#14
Thomas F Münte, Josep Marco-Pallares, Seza Bolat, Marcus Heldmann, Götz Lütjens, Wido Nager, Kirsten Müller-Vahl, Joachim K Krauss
BACKGROUND: The globus pallidus internus (GPi) is the final output relay of the basal ganglia for the control of movements but has also been shown to belong to a second pathway projecting to the lateral habenula. This latter pathway is related to reward processing. METHOD: This prompted us to record, in eight patients receiving deep brain stimulation of the GPi for the alleviation of various movement disorders, local field potentials (LFP) while these patients performed a lottery task...
February 14, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28259544/deep-brain-stimulation-to-the-medial-forebrain-bundle-for-depression-long-term-outcomes-and-a-novel-data-analysis-strategy
#15
Bettina H Bewernick, Sarah Kayser, Sabrina M Gippert, Christina Switala, Volker A Coenen, Thomas E Schlaepfer
BACKGROUND: Deep brain stimulation (DBS) of the supero-lateral branch of the medial forebrain bundle (slMFB) in treatment-resistant depression (TRD) is associated with acute antidepressant effects. OBJECTIVE: Long-term clinical effects including changes in quality of life, side effects and cognition as well as long-term data covering four years are assessed. METHODS: Eight TRD patients were treated with DBS bilateral to the slMFB. Primary outcome measure was a 50% reduction in Montgomery-Åsberg Depression Rating Scale (MADRS) (response) and remission (MADRS <10) at 12 months compared to baseline...
February 9, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28209346/reliability-of-tms-phosphene-threshold-estimation-toward-a-standardized-protocol
#16
Chiara Mazzi, Silvia Savazzi, Arman Abrahamyan, Manuela Ruzzoli
BACKGROUND: Phosphenes induced by transcranial magnetic stimulation (TMS) are a subjectively described visual phenomenon employed in basic and clinical research as index of the excitability of retinotopically organized areas in the brain. OBJECTIVE: Phosphene threshold estimation is a preliminary step in many TMS experiments in visual cognition for setting the appropriate level of TMS doses; however, the lack of a direct comparison of the available methods for phosphene threshold estimation leaves unsolved the reliability of those methods in setting TMS doses...
February 2, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28196679/successful-dorsomedial-prefrontal-rtms-for-major-depression-in-borderline-personality-disorder-three-cases
#17
LETTER
Kfir Feffer, Sarah K Peters, Kamaldeep Bhui, Jonathan Downar, Peter Giacobbe
No abstract text is available yet for this article.
February 2, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28161228/antidepressant-remission-to-dtms-of-the-dmpfc-and-acc-in-lateral-pfc-dtms-nonresponders-case-series
#18
LETTER
A Tendler, E Sisko, N Barnea-Ygael, M DeLuca, N Rodriguez, S Corbett-Methott, J Sutton, A Zangen
No abstract text is available yet for this article.
January 24, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28162976/neuromodulation-in-response-to-electroconvulsive-therapy-in-schizophrenia-and-major-depression
#19
Philipp Arthur Thomann, Robert Christian Wolf, Henrike Maria Nolte, Dusan Hirjak, Stefan Hofer, Ulrich Seidl, Malte Sebastian Depping, Bram Stieltjes, Klaus Maier-Hein, Fabio Sambataro, Torsten Wüstenberg
BACKGROUND: Electroconvulsive therapy (ECT) is one of the most effective treatments in severe and treatment-resistant major depressive disorder (MDD). ECT has been also shown to be effective in schizophrenia (SZ), particularly when rapid symptom reduction is needed or in cases of resistance to drug-treatment. However, its precise mechanisms of action remain largely unknown. OBJECTIVE/HYPOTHESIS: This study examined whether ECT exerts disorder-specific or unspecific modulation of brain structure and function in SZ and MDD...
January 16, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28117177/two-indications-one-target-concomitant-epilepsy-and-tourettism-treated-with-centromedian-parafascicular-thalamic-stimulation
#20
LETTER
Marina Picillo, Mohammad Rohani, Andres M Lozano, Alfonso Fasano
No abstract text is available yet for this article.
January 12, 2017: Brain Stimulation
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