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Archives of Cardiovascular Diseases

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https://www.readbyqxmd.com/read/28209375/suboptimal-achievement-of-low-density-lipoprotein-cholesterol-targets-in-french-patients-with-coronary-heart-disease-contemporary-data-from-the-dysis-ii-acs-chd-study
#1
Jean Ferrières, Maja Velkovski Rouyer, Dominik Lautsch, Veronica Ashton, Baishali M Ambegaonkar, Philippe Brudi, Anselm K Gitt
BACKGROUND: European guidelines recommend a low-density lipoprotein cholesterol (LDL-C) target of<1.8mmol/L (70mg/dL), and/or a≥50% reduction when the target level cannot be reached, for patients at very high cardiovascular risk, and high-potency lipid-lowering therapy (LLT) in patients with an acute coronary syndrome (ACS). AIM: To document the prevalence of lipid abnormalities and the achievement of lipid targets among patients surviving an ACS and in patients with stable coronary heart disease (CHD), using data from the DYSIS II study...
February 13, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28189387/absolute-iron-deficiency-without-anaemia-in-patients-with-chronic-systolic-heart-failure-is-associated-with-poorer-functional-capacity
#2
Joffrey Pozzo, Pauline Fournier, Clément Delmas, Paul-Louis Vervueren, Jérôme Roncalli, Meyer Elbaz, Michel Galinier, Olivier Lairez
BACKGROUND: Functional status is one of the main concerns in the management of heart failure (HF). Recently, the FAIR-HF and CONFIRM-HF trials showed that correcting anaemia using intravenous iron supplementation improved functional variables in patients with absolute or relative iron deficiency. Relative iron deficiency is supposed to be a marker of HF severity, as ferritin concentration increases with advanced stages of HF, but little is known about the impact of absolute iron deficiency (AID)...
February 8, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28139456/primary-angioplasty-effect-of-deferred-stenting-on-stent-size
#3
Brahim Harbaoui, Philippe Emsellem, Emmanuel Cassar, Cyril Besnard, Raphael Dauphin, Pascal Motreff, Pierre-Yves Courand, Pierre Lantelme
BACKGROUND: Primary angioplasty with immediate stenting (IS) is the gold standard for ST-segment elevation myocardial infarction (STEMI). Deferred stenting (DS) has been proposed to limit periprocedural complications, and may influence stent size because of thrombus and spasm alleviation. AIM: We sought to study the effect of DS on stent size. METHODS: Over the study period, 258 patients underwent primary angioplasty for STEMI (DS, n=84; IS, n=174)...
January 27, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28139455/vascular-anatomy-in-children-with-univentricular-hearts-regarding-transcatheter-bidirectional-glenn-anastomosis
#4
Aleksander Sizarov, Francesca Raimondi, Damien Bonnet, Younes Boudjemline
BACKGROUND: Transcatheter stent-secured Glenn anastomosis, aiming to reduce the invasiveness of palliation in patients with univentricular heart defects, has been reported in large experimental animals. The advent of biodegradable stents and tissue-engineered vascular grafts will make this procedure a reality in human patients. However, the relationship between the superior vena cava (SVC) and the right pulmonary artery (RPA) is different in humans. AIM: To characterise vascular anatomy in children with univentricular hearts, regarding technical aspects and device design for this procedure...
January 27, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28139454/brugada-syndrome-diagnosis-risk-stratification-and-management
#5
REVIEW
Jean-Baptiste Gourraud, Julien Barc, Aurélie Thollet, Hervé Le Marec, Vincent Probst
Brugada syndrome is a rare inherited arrhythmia syndrome leading to an increased risk of sudden cardiac death, despite a structurally normal heart. Diagnosis is based on a specific electrocardiogram pattern, observed either spontaneously or during a sodium channel blocker test. Among affected patients, risk stratification remains a challenge, despite recent insights from large population cohorts. As implantable cardiac defibrillators - the main therapy in Brugada syndrome - are associated with a high rate of complications in this population, the main challenge is risk stratification of patients with Brugada syndrome...
January 27, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28139453/how-best-to-train-doctors-in-adult-congenital-heart-disease
#6
Philippe Acar
No abstract text is available yet for this article.
January 27, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28131703/left-ventricular-geometry-and-aortic-stenosis-the-intriguing-association
#7
LETTER
Marijana Tadic, Branislava Ivanovic
No abstract text is available yet for this article.
January 25, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28117249/downhill-exercise-training-in-monocrotaline-injected-rats-effects-on-echocardiographic-and-haemodynamic-variables-and-survival
#8
Irina Enache, Fabrice Favret, Stéphane Doutreleau, Paola Goette Di Marco, Anne-Laure Charles, Bernard Geny, Anne Charloux
BACKGROUND: Eccentric exercise training has been shown to improve muscle force strength without excessive cardiovascular stress. Such an exercise modality deserves to be tested in pulmonary arterial hypertension. AIM: We aimed to assess the effects of an eccentric training modality on cardiac function and survival in an experimental monocrotaline-induced model of pulmonary arterial hypertension with right ventricular dysfunction. METHODS: Forty rats were randomly assigned to one of four groups: 40mg/kg monocrotaline-injected sedentary rats; 40mg/kg monocrotaline-injected eccentric-trained rats; sedentary control rats; or eccentric-trained control rats...
January 20, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28117248/characteristics-aetiological-spectrum-and-management-of-valvular-heart-disease-in-a-tunisian-cardiovascular-centre
#9
Faten Triki, Jihen Jdidi, Dorra Abid, Nada Tabbabi, Selma Charfeddine, Sahar Ben Kahla, Mourad Hentati, Leila Abid, Samir Kammoun
BACKGROUND: Valvular heart diseases occur frequently in Tunisia, but no precise statistics are available. AIM: To analyse the characteristics of patients with abnormal valvular structure and function, and to identify the aetiological spectrum, treatment and outcomes of valvular heart disease in a single cardiovascular centre in Tunisia. METHODS: This retrospective study included patients with abnormal valvular structure and function, who were screened by transthoracic echocardiography at a single cardiology department between January 2010 and December 2013...
January 20, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28117247/severe-right-ventricular-dysfunction-is-an-independent-predictor-of-pre-and-post-transplant-mortality-among-candidates-for-heart-transplantation
#10
Eleonore Ravis, Alexis Theron, Julien Mancini, Nicolas Jaussaud, Pierre Morera, Virginie Chalvignac, Catherine Guidon, Dominique Grisoli, Vlad Gariboldi, Alberto Riberi, Gilbert Habib, Annick Mouly-Bandini, Frederic Collart
BACKGROUND: Heart transplantation is the gold-standard treatment for end-stage heart failure. However, the shortage of grafts has led to longer waiting times and increased mortality for candidates without priority. AIMS: To study waiting-list and post-transplant mortality, and their risk factors among patients registered for heart transplantation without initial high emergency procedure. METHODS: All patients registered on the heart transplantation waiting list (2004-2015) without initial high emergency procedure were included...
January 20, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28117246/radiotherapy-induced-right-ventricular-remodelling-the-missing-piece-of-the-puzzle
#11
REVIEW
Marijana Tadic, Cesare Cuspidi, Dagmara Hering, Lucia Venneri, Isidora Grozdic-Milojevic
The number of studies demonstrating that right ventricular structure, function and mechanics are valuable predictors of cardiovascular and total morbidity and mortality in patients with a wide range of cardiovascular conditions is constantly increasing. Most studies that evaluated the influence of radiotherapy on the heart focused on left ventricular remodelling, which is why current guidelines only recommend detailed assessment of the left ventricle. Data regarding right ventricular changes in cancer patients treated with radiotherapy are scarce...
January 20, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28117245/the-medical-value-and-cost-effectiveness-of-an-exercise-test-for-sport-preparticipation-evaluation-in-asymptomatic-middle-aged-white-male-and-female-athletes
#12
Laurent Chevalier, Gaelle Kervio, Stephane Doutreleau, Jean-Philippe Mathieu, Jean-Michel Guy, Aude Mignot, Luc Corneloup, François Passard, Thierry Laporte, Aude Girard-Girod, Olivier Hennebert, Philippe Bernadet, Marie-Pierre Vincent-Chevalier, Laurent Gencel, François Carré
BACKGROUND: Cardiovascular events related to high-intensity sport practice are rare but dramatic. Coronary artery disease (CAD) is the leading cause of these events after the age of 35 years. The value of a maximal exercise test (ET) for detection of athletes at risk remains a matter of debate. AIM: The aim of this prospective multicentre study was to clarify the medical value and cost-effectiveness of an ET in middle-aged white asymptomatic athletes who participate in high-intensity sport...
January 20, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28117244/radial-versus-femoral-access-for-coronary-angiography-and-intervention-is-associated-with-lower-patient-radiation-exposure-in-high-radial-volume-centres-insights-from-the-ray-act-1-study
#13
Jean-Louis Georges, Loic Belle, Ludovic Meunier, Thierry Dechery, Khalifé Khalifé, Max Pecheux, Simon Elhaddad, Nicolas Amabile, Michel Pansieri, Jacques Ballout, Xavier Marchand, Gilles Rouault, Pierre Leddet, Olivier Nugue, Nicolas Lucke, Simon Cattan
BACKGROUND: Literature suggests that radial access is associated with higher radiation doses than femoral access. AIMS: To compare patient radiation exposure during coronary angiography (CA) and percutaneous coronary intervention (PCI) with radial versus femoral access. METHODS: RAY'ACT is a nationwide, multicentre, French survey evaluating patient radiation in interventional cardiology. Variables of patient exposure from 21,675 CAs and 17,109 PCIs performed at 44 centres during 2010 were analysed retrospectively...
January 20, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28082243/clinical-outcomes-in-myocardial-infarction-and-multivessel-disease-after-a-cardiac-rehabilitation-programme-partial-versus-complete-revascularization
#14
Ricardo Mori Junco, Regina Dalmau Gonzalez-Gallarza, Almudena Castro Conde, Oscar González Fernandez, Carlos Álvarez Ortega, Zorba Blázquez Bermejo, Luis Furuya-Kanamori, Raúl Moreno Gomez, Esteban López de Sa Arreses
BACKGROUND: Current guideline recommendations encourage culprit vessel only percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease. However, recent studies have shown a better clinical outcome in patients who receive multivessel PCI. AIM: To measure and compare clinical outcomes between partial revascularization (PR) versus complete revascularization (CR) in patients with STEMI and multivessel disease who underwent a cardiac rehabilitation programme...
January 9, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28065448/left-ventricular-dyssynchrony-and-2d-and-3d-global-longitudinal-strain-for-differentiating-physiological-and-pathological-left-ventricular-hypertrophy
#15
Julien Ternacle, Camille Bremont, Thomas d'Humieres, Laureline Faivre, Huy Long Doan, Romain Gallet, Leopold Oliver, Jean-Luc Dubois-Randé, Pascal Lim
BACKGROUND: Diagnosis of hypertrophic cardiomyopathy (HCM) in athletes can be challenging. AIMS: To ascertain parameters that differentiate patients with HCM from athletes with moderate left ventricular (LV) hypertrophy (LVH 13-15mm). METHODS: We retrospectively included 100 men: 50 elite rugby players (25 with moderate LVH and 25 with no LVH), 25 patients with HCM and moderate LVH and 25 controls. LV dyssynchrony was defined as the standard deviation of time to peak 2D longitudinal strain (16-segment model) and global strain components were computed from two- (2D) and three-dimensional (3D) speckle tracking...
January 3, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28065447/percutaneous-left-atrial-appendage-closure-followed-by-single-antiplatelet-therapy-short-and-mid-term-outcomes
#16
Zakaria Jalal, Marie-Lou Dinet, Nicolas Combes, Xavier Pillois, Pauline Renou, Igor Sibon, Xavier Iriart, Jean-Benoît Thambo
BACKGROUND: After left atrial appendage closure (LAAC), various antithrombotic protocols have been suggested, but the optimal post-procedural antithrombotic strategy is still under debate. AIMS: To investigate the efficacy and safety of LAAC with an AMPLATZER™ Cardiac Plug (ACP) device (St. Jude Medical, Minneapolis, MN, USA) followed by single antiplatelet therapy. METHODS: Consecutive patients with non-valvular atrial fibrillation and a contraindication for oral anticoagulants who underwent LAAC with an ACP device between 2012 and 2014 in two French centres were included...
January 3, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28065445/colin-trial-value-of-colchicine-in-the-treatment-of-patients-with-acute-myocardial-infarction-and-inflammatory-response
#17
Mariama Akodad, Benoît Lattuca, Nicolas Nagot, Vera Georgescu, Mathilde Buisson, Jean-Paul Cristol, Florence Leclercq, Jean-Christophe Macia, Richard Gervasoni, Thien-Tri Cung, Stéphane Cade, Frédéric Cransac, Jessica Labour, Anne-Marie Dupuy, François Roubille
BACKGROUND: Inflammation is involved during acute myocardial infarction, and could be an interesting target to prevent ischaemia-reperfusion injuries. Colchicine, known for its pleiotropic anti-inflammatory effects, could decrease systemic inflammation in this context. AIMS: To evaluate the impact of colchicine on inflammation in patients admitted for ST-segment elevation myocardial infarction (STEMI). METHODS: All patients admitted for STEMI with one of the main coronary arteries occluded, and successfully treated with percutaneous coronary intervention, were included consecutively...
January 3, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28043783/pulmonary-homograft-stenosis-in-the-ross-procedure-incidence-clinical-impact-and-predictors-in-long-term-follow-up
#18
Laura Pardo González, Martin Ruiz Ortiz, Mónica Delgado, Dolores Mesa, Rafael Villalba, Sara Rodriguez, Francisco J Hidalgo, Pedro Alados, Jaime Casares, Jose Suarez de Lezo
BACKGROUND: The Ross procedure is used in the treatment of selected patients with aortic valve disease. Pulmonary graft stenosis can appear in the long-term follow-up after the Ross intervention, but the factors involved and its clinical implications are not fully known. AIM: To describe the incidence, clinical impact and predictors of homograft stenosis and reintervention after the Ross procedure in a prospective series in a tertiary referral hospital. METHODS: From 1997 to 2009, 107 patients underwent the Ross procedure (mean age: 30±11 years; 69% men; 21 aged<18 years), and were followed for echocardiographic homograft stenosis (peak gradient>36mmHg) and surgical or percutaneous homograft reintervention...
December 30, 2016: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28034627/two-dimensional-right-ventricular-strain-by-speckle-tracking-for-assessment-of-longitudinal-right-ventricular-function-after-paediatric-congenital-heart-disease-surgery
#19
Clement Karsenty, Khaled Hadeed, Yves Dulac, Florent Semet, Xavier Alacoque, Sophie Breinig, Bertrand Leobon, Philippe Acar, Sebastien Hascoet
BACKGROUND: Right ventricular (RV) function is a prognostic marker of cardiac disease in children. Speckle tracking has been developed to assess RV longitudinal shortening, the dominant deformation during systole; little is known about its feasibility in children with congenital heart disease (CHD). AIMS: To evaluate the feasibility and reproducibility of RV two-dimensional (2D) strain assessed by speckle tracking in infants undergoing CHD surgery compared with conventional markers...
December 26, 2016: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28024917/transposition-of-the-great-arteries-rationale-for-tailored-preoperative-management
#20
REVIEW
Pierre-Emmanuel Séguéla, François Roubertie, Bernard Kreitmann, Philippe Mauriat, Nadir Tafer, Zakaria Jalal, Jean-Benoit Thambo
As preoperative morbi-mortality remains significant, care of newborns with transposition of the great arteries is still challenging. In this review of the literature, we discuss the different treatments that could improve the patient's condition into the preoperative period. Instead of a standardized management, we advocate personalized care of these neonates. Considering the deleterious effects of hypoxia, special attention is given to the use of non-invasive technologies to assess oxygenation of the tissues...
December 23, 2016: Archives of Cardiovascular Diseases
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