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Iranian Journal of Parasitology

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https://www.readbyqxmd.com/read/29963099/an-atypical-presentation-of-disseminated-mucocutaneous-leishmaniasis-caused-by-leishmania-major-in-iran
#1
Pedram Normohamadpur, Forugh Ghaedi
Although leishmaniasis is an endemic disease in Iran the mucosal involvement is rare. Mucocutaneous leishmaniasis (MCL) mainly caused by Leishmanial braziliensis infection, reported with other Leishmania species such as L. major . Herein a 78 yr old man with MCL from Iran is presented who referred to Razi Hospital Dermatology Clinic, Tehran, Iran, for multiple ulcerative lesions on mid face skin, mucosa of upper lip and anterior fossa of nose, dorsal aspect of the hands and the posterior aspect of heels. Skin biopsy revealed necrotizing and granulomatous tissue pattern that suggested infection pathogenesis but the smear for leishmaniasis, Mycobacterium spp, and fungal elements was negative at first...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963098/molecular-evaluation-of-a-case-of-fasciola-hepatica-in-wild-boar-in-southwestern-iran-a-case-report
#2
Bahador Sarkari, Majid Mansouri, Shamsi Noorpisheh Ghadimi, Samaneh Abdolahi Khabisi, Abdolla Doshmanziari
Wild boars may be infected with several zoonotic parasitic infections including Fasciola spp. We reported a case of Fasciola infection in a wild boar in Bushehr Province in southwestern Iran. The sample was isolated from the liver of a hunted wild boar. A few of adult worms were fixed and stained. DNA was extracted from apical and lateral parts of the worms and PCR amplified, targeting NADH dehydrogenase subunit 1 (nad1) and cytochrome C oxidase subunit 1 (cox1) mitochondrion genes. Although the worm was quite long and looked much similar to F...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963097/brain-parenchyma-pons-involvement-by-visceral-leishmaniasis-a-case-report
#3
Moslem Sedaghattalab, Arsalan Azizi
Leishmaniasis, as a vector-borne disease, is transmitted by sandfly and caused by Leishmania protozoa. Brain involvement rarely occurs in visceral leishmaniasis. In this paper, a rare case of pons involvement by visceral leishmaniasis (VL) is reported. A 54 yr old man from Southwest of Iran (Yasuj) presented to the Emergency Ward with a 3-wk history of headache (continuous, throbbing, and general), fever, chills, weakness, anorexia, and weight loss.
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963096/a-preliminary-survey-on-gastrointestinal-parasites-of-domestic-ducks-in-ahvaz-southwest-iran
#4
Sara Larki, Alireza Alborzi, Rahil Chegini, Rezvan Amiri
Background: Despite ducks being birds resistant to infection, the favorable habitat of ducks such as subtropical climate or stagnant water is also a perfect place for survival of the parasites. Methods: This study was conducted from Dec 2014 to Apr 2015 to determine the prevalence of gastrointestinal parasites of domestic ducks in Ahvaz and environs, southwest of Iran. Overall, 41 fresh fecal samples were collected and prepared using formol-ether concentration, modified Ziehl-Neelsen, sheather`s floatation and zinc sulfate sedimentation methods...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963095/comparative-study-of-wheatley-s-trichrome-stain-and-in-vitro-culture-against-pcr-assay-for-the-diagnosis-of-blastocystis-sp-in-stool-samples
#5
Nabilah Amelia Mohammad, Mohd Fahmi Mastuki, Hesham M Al-Mekhlafi, Norhayati Moktar, Tengku Shahrul Anuar
Background: This study evaluated the performance of routine permanent stain and cultivation method in comparison with polymerase chain reaction assay as the reference technique to detect Blastocystis sp. Methods: A cross-sectional study was conducted among aboriginal populations that reside in Pahang, Peninsular Malaysia in Feb to Mar 2015. A total of 359 stool samples were examined using Wheatley's trichrome stain, in-vitro cultivation in Jones' medium and PCR assay...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963094/genetic-characterization-of-hydatid-cysts-isolated-from-domestic-animals-in-lorestan-province-western-iran
#6
Farnaz Kheirandish, Ebrahim Badparva, Hossein Mahmmoudvand, Elahe Beiranvand, Simin Babaei, Bahram Nasiri
Background: Regarding hydatid cyst (cystic echinococcosis, CE) as a human public health problem in the West of Iran, molecular data related to the genotypes of Echinococcus granulosus in cattle and sheep in these regions are still insufficient. Here, we evaluated the genotypes of E. granulosus infecting sheep and cattle in western Iran. Methods: Totally, 36 hydatid cysts including 18 hydatid cysts of sheep and 18 hydatid cysts of cattle were collected from Khorramabad slaughterhouse (Lorestan Province), Western Iran between May to September 2014...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963093/epidemiology-and-molecular-prevalence-of-toxoplasma-gondii-in-cattle-slaughtered-in-zahedan-and-zabol-districts-south-east-of-iran
#7
Davood Anvari, Dariush Saadati, Reza Nabavi, Majid Alipour Eskandani
Background: Toxoplasma gondii is an obligate, intracellular parasite which causes the toxoplasmosis in humans and warm-blooded animals. Red meat is an important source for transmission of the infection to humans. This study aimed to determine the prevalence of Toxoplasma among imported and indigenous cattle in the Sistan region. Methods: One hundred samples from slaughtered cattle were collected from two abattoirs of Zabol and Zahedan, South East of Iran in 2015...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963092/the-prevalence-of-trichomoniasis-in-women-referred-to-clinical-centers-in-south-of-tehran-iran-during-2015-2016
#8
Akram Azambakhtiar, Bahram Nikmanesh, Mostafa Rezaeian, Nasrin Dashti, Fatemeh Safari, Mitra Zarebavani
Background: This study aimed to estimate the prevalence of trichomoniasis infection among females in Tehran, Iran. Methods: This study was conducted on 482 women referred to the 6 obstetrics and gynecology centers of Tehran during 2015-2016. Some information including education, occupation, and number of sexual partners was obtained and clinical signs and symptoms of the genital tract were diagnosed by clinical examination. Two swabs were collected from the posterior fornix of patients...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963091/additional-glance-on-the-role-of-dientamoeba-fragilis-blastocystis-hominis-in-patients-with-irritable-bowel-syndrome
#9
Ayman Nabil Ibrahim, Ayman Mohamed Al-Ashkar, John Talaat Nazeer
Background: Irritable bowel syndrome (IBS) is a functional gastrointestinal disease with high population prevalence. Dientamoeba fragilis and Blastocystis hominis are reported worldwide as a cause of human gastrointestinal symptoms. This study evaluated the possible link between this syndrome and the infection with D. fragilis and B. hominis in Egypt. Methods: Overall, 310 stool samples (160 from IBS patients and 150 from controls) were obtained from Tropical Medicine Outpatient Clinic, Faculty of Medicine, Ain Shams University, Cairo, Egypt between Mar 2015 and Feb 2016...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963090/trypanocidal-effects-of-cisplatin-alone-and-in-combination-with-nigella-sativa-oil-on-experimentally-infected-mice-with-trypanosoma-evansi
#10
Nashaat Abd El-Monem Nassef, Manal Ahmed El-Melegy, Engy Victor Beshay, Dalia Rifaat Al-Sharaky, Tahany Mohamed Al-Attar
Background: Due to the limited number of the available drugs for the treatment of trypanosomiasis, this study was designed to evaluate the trypanocidal effects of cisplatin or/and Nigella sativa oil (NSO) in experimentally infected mice with T. evansi . Methods: During 2015 at the Parasitology Department, Menoufia University, Menoufia, Egypt, sixty Swiss albino mice were divided into six groups: normal control (I), infected control (II); cisplatin-treated (III); NSO-treated (IV); combined cisplatin + NSO-treated (V) and diminazene-treated (VI)...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963089/comparative-functional-study-of-thioester-containing-related-proteins-in-the-recently-sequenced-genome-of-biomphalaria-glabrata
#11
Mofolusho O Falade, Benson Otarigho
Background: There is paucity of information on functional relationship and characterization of Biomphalaria glabrata thioester-containing proteins ( Bg TEP) to other well-annotated homologues. We performed functional characterization studies of Bg TEP to homologues in Anopheles gambiae and in disparate invertebrates. Methods: Genomic sequences of TEPs were retrieved after annotation of the B. glabrata genome. In addition, TEP sequences deposited in NCBI protein database were also retrieved and utilized for sequence analysis...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963088/induction-of-apoptosis-by-alcoholic-extract-of-combination-verbascum-thapsus-and-ginger-officinale-on-iranian-isolate-of-trichomonas-vaginalis
#12
Zohreh Fakhrieh-Kashan, Mohsen Arbabi, Mahdi Delavari, Mahdi Mohebali, Hossein Hooshyar
Background: The protozoan Trichomonas vaginalis is a sexually transmitted disease (STD). Metronidazole is a chosen drug for the treatment. This study evaluated the anti trichomonal activity of alcoholic extracts of combination Verbascum thapsus and Ginger officinale. Methods: This experimental study was conducted in the Parasitology Laboratory, Kashan University of Medical Sciences, Kashan, Iran in 2015, on 23 women with suspected trichomoniasis referring to Kashan clinical centers...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963087/canine-visceral-leishmaniasis-a-seroepidemiological-survey-in-jiroft-district-southern-kerman-province-southeastern-iran-in-2015
#13
Mohammad Javad Abbaszadeh Afshar, Iraj Sharifi, Mehdi Bamorovat, Mehdi Mohebali, Mohammad Saleh Bahreini, Afsaneh Naderi
Background: Domestic dogs have been implicated as the main reservoir host of Mediterranean type of visceral leishmaniasis (VL) that is endemic in some parts of Iran. This study was performed about role of dogs in canine VL (CVL) epidemiology in Jiroft District, south of Kerman Province, southeastern Iran. Methods: Totally, 165 dogs including 100 stray and 65 sheepdogs were randomly selected. After complete clinical examination blood sample was taken from each dog...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963086/incidence-of-antenatal-trichomoniasis-and-evaluation-of-its-role-as-a-cause-of-preterm-birth-in-pregnant-women-referring-to-minia-university-hospital-egypt
#14
Amany Mohamed Kamal, Azza Kamal Ahmed, Nawras Mohamed El-Saghier Mowafy, Hossam Eldin Shawki, Ahmed Samir Sanad, Eptesam Esmail Hassan
Background: We aimed to determine the incidence of trichomoniasis and its risk factors in Egyptian pregnant women attending the Minia Maternity and Pediatric University Hospital, Minia, Egypt and evaluate its association with preterm birth. Methods: The study was carried out from Aug 2014 to Jun 2015 through 2 phases, the first phase was case-control study, and the second phase was follow-up with intervention. Overall, 300 pregnant women with gestational age of 20-36 weeks with no medical risk factors of preterm labour birth were enrolled...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963085/phylogenetic-analysis-of-c-type-lectin-from-toxocara-canis-infective-larvae-and-comparison-with-the-c-type-lectin-family-in-the-immune-system-of-mouse-and-human
#15
Fazeleh Etebar, Seyed Hossein Hosseini, Fatemeh Jalousian, Mohammad Mehdi Ranjbar
Background: C type lectin (CTL) family is a type of calcium-dependent proteins found in vertebrates and invertebrates. The objective of this study was to perform a comparative analysis and phylogenetic inferring for understanding the similarities and differences of carbohydrate recognition domain (CRD) domain of Toxocara canis CTL and other nematodes, and similar C type lectin involved in the immune system of mouse and human as their host. Methods: The female T...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963084/identification-of-antigenic-and-immunogenic-proteins-of-toxoplasma-gondii-in-human-and-sheep-by-immunoproteomics
#16
Mohammad Taghi Ahady, Nasser Hoghooghi-Rad, Rasool Madani, Ahmad Reza Esmaeili Rastaghi
Background: Toxoplasmosis is a parasitic disease caused by the intracellular protozoan parasite, Toxoplasma gondii , which can infect humans and warm-blooded animals. This infection can lead to still birth and abortion among some susceptible hosts especially sheep and human in pregnancy. Development of a vaccine against T. gondii infection is very important-especially for use in immunocompromised patients, pregnant women, and sheep. Different antigens of T. gondii can be potential candidates for immunization...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963083/monitoring-the-response-of-plasmodium-vivax-to-chloroquine-and-uncomplicated-p-falciparum-to-artesunate-fansidar-antimalarials-in-southeastern-iran
#17
Hamid Azarian Moghadam, Mehdi Nateghpour, Ahmad Raeisi, Afsane Motevalli Haghi, Gholamhosein Edrissian, Leila Farivar
Background: For many years, malaria was a major life-threatening parasitic infection in Iran. Although malaria elimination program is implementing in the country, still some cases annually are reported from malaria-endemic areas. Methods: This study was conducted in five malaria endemic districts of Sistan and Baluchistan Province, southeastern Iran, neighboring Afghanistan and Pakistan countries. Overall, 170 and 38 vivax malaria and falciparum malaria infected patients were enrolled in the study from 2013-2014...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963082/synchronous-identification-of-entamoeba-histolytica-giardia-intestinalis-and-cryptosporidium-spp-in-stool-samples-using-a-multiplex-pcr-assay
#18
Amir Bairami, Sasan Rezaei, Mostafa Rezaeian
Background: Diarrheal disease annually causes 760000 deaths in children, and 1700 million new cases are reported each year worldwide. Among the parasites, Entamoeba histolytica , Giardia intestinalis , and Cryptosporidium spp. are the most important infectious agents leading to diarrhea. Clinical presentations due to these parasites are more or less similar, and microscopy is not as much as sensitive for the detection. The aim of this study was to set up and evaluate a Multiplex PCR Assay for Synchronous Identification of Entamoeba histolytica , Giardia intestinalis , and Cryptosporidium spp...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963081/immunoprophylactic-potential-of-a-cocktail-of-three-low-molecular-weight-antigens-of-leishmania-donovani-along-with-various-adjuvants-against-experimental-visceral-leishmaniasis
#19
Harpreet Kaur, Ankita Thakur, Sukhbir Kaur
Background: Currently, there is no vaccine available for any form of leishmaniasis for human use, including visceral leishmaniasis (VL). The treatment relies on drugs associated with severe toxic side effects and increased parasite drug resistance. At present, there is a strong need to develop and implement a successful vaccine against this disease. Therefore, we evaluated immunoprophylactic potential of a cocktail of low molecular weight antigens along with various adjuvants. Methods: The three antigens (2015, Department of Zoology, Panjab University, Chandigarh), 31kDa, 36 kDa and 51 kDa of L...
January 2018: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/29963080/malaria-vaccine-development-the-need-for-novel-approaches-a-review-article
#20
REVIEW
Shima Mahmoudi, Hossein Keshavarz
Background: Although rigorous efforts have substantially decreased the malaria burden through decades, it still threatens the lives of millions of children. Development of an effective vaccine can provide important approach in malaria control strategies. Unfortunately, development of an effective vaccine for falciparum malaria has been hindered by the extreme complexity of malaria parasite biology, complex and diverse parasite genomes, and immune evasion by the parasites as well as the intricate nature of the parasites infection cycle...
January 2018: Iranian Journal of Parasitology
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