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Diabetes & Metabolic Syndrome

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https://www.readbyqxmd.com/read/28087246/adipocytokines-and-anthropometric-measures-in-type-2-diabetics
#1
Shubhangi M Harke, Suresh P Khadke, Abhijit A Ghadge, Ashwini S Manglekar, Shashank S Shah, Arundhati G Diwan, Aniket A Kuvalekar
AIM: Type 2 diabetes mellitus has assumed pandemic proportions worldwide. Aggressive management of hyperglycemia in diabetics is a primary goal of treatment. We have previously reported favorable effects of oral hypoglycemic agents on adipocytokines. Aim of the present study was to investigate the relationship of adipocytokines with anthropometric measures and biochemical parameters in type 2 diabetics. METHODS: Clinically diagnosed type 2 diabetics and age, gender matched healthy volunteers were recruited for study...
December 30, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28057507/association-between-thyroid-hormone-parameters-and-dyslipidemia-among-type-2-diabetes-mellitus-patients-comparative-cross-sectional-study
#2
Amare Desalegn Wolide, Belay Zawdie, Tilahun Alemayehu, Samuel Tadesse
BACKGROUND: The relationship between thyroid function and lipid profile has been documented in T2DM and healthy subjects. The aim of the current study was to assess the association between thyroid hormone parameters and dyslipidemia in T2DM and non-diabetic study participants. METHOD AND MATERIALS: In this comparative cross-sectional study, 214 type 2 diabetic and 214 non-diabetic study participants were enrolled. Clinical and anthropometric data were collected from all study participants...
December 26, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28057504/prevalence-of-low-hdl-cholesterol-and-its-associations-among-sri-lankan-patients-with-diabetes-mellitus-on-statin-therapy
#3
Thilak Priyantha Weerarathna, Herath Mudiyanselage Meththananda Herath, Gayani Liyanage
AIMS: We aimed to study the prevalence and associations of suboptimal high density lipoproteins level, a characteristic feature in diabetic dyslipidemia among patients under statin therapy. MATERIALS AND METHODS: From a database of 2416 patients, data on age, gender, duration of diabetes, body mass index (BMI) and waist circumference (WC), low density lipoproteins (LDL), triglyceride, high density lipoproteins (HDL) were obtained. Prevalence of suboptimal HDL (<40mg/dL in males and <50mg/dL in females) and its association with gender, age, duration of diabetes, BMI and WC were studied...
December 26, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28041922/metabolic-parameters-in-diabetic-neuropathic-patients-after-treatment-with-pregabalin
#4
O A Abou Zeid, N Y Elkhouly, E N Osman, M H Youssef
OBJECTIVE: To assess metabolic parameters in patients with diabetic peripheral neuropathy (DPN) before and after 3 months treatment with a flexible dose pregabalin. METHODS: This is a prospective clinical trial. The metabolic parameters observed and recorded after 3 months treatment with a flexible dose pregabalin (n=331). RESULTS: The lipid profile parameters were significantly improved after treatment, total cholesterol, TC (P<0.01, 95% CI, 25...
December 26, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28041920/secondary-cvd-prevention-lipid-modification-strategies-a-critical-analysis
#5
REVIEW
Samit Ghosal, Binayak Sinha
Lipid modification holds the key to effective secondary prevention of cardiovascular disease (CVD). However there is a controversy on whether it's all about targeting specific lipid sub fractions to a particular level or a direct effect of the agent(s) used or both. This review intends to look into these important issues from an evidence-based perspective. What is the appropriate timing of testing for lipid profile after a cardiovascular event? What is the rationale behind initiating with a high dose statin after an acute coronary event? What is the role of targeting lipid sub fractions beside LDL cholesterol? Is there any role for non-statin based therapy after an acute cardiovascular event? What constitutes a long-term lipid modification strategy in patients post CVD? These are very important questions, which needs to be addressed adequately as well as scientifically...
December 26, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28034691/glycaemic-control-in-sudanese-individuals-with-type-2-diabetes-population-based-study
#6
Sufian K Noor, Wadie M Elmadhoun, Sarra O Bushara, Ahmed O Almobarak, Reham S Salim, Sittana A Forawi, Heitham Awadallah, Einas S Elwali, Mohamed H Ahmed
BACKGROUND: Diabetes mellitus (DM) is a major health problem in Sudan and is a leading cause of morbidity and mortality. The objective of this study was to determine the prevalence of glycaemic control among individuals with type 2 diabetes across different cities in Sudan. METHODS: Individuals with type 2 diabetes attending selected diabetes centres in Sudan, who had been on treatment for DM for at least one year and volunteered to participate were included. Participants were interviewed using standardized pretested questionnaire to record medical history, sociodemographic and life style characteristics...
December 26, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28043817/risk-factors-of-diabetes-mellitus-amongst-the-executives-of-an-industrial-area-of-north-east-india-a-community-based-cross-sectional-study
#7
Sultana Jesmin Ahmed, Mir Alam Siddique, Alak Barua, Hiranya Saikia
AIM: To assess risk factors of diabetes mellitus amongst the executives of an industrial area of North East India. MATERIAL AND METHOD: Executive the aged 20 to 60 years were selected by simple random sampling in a community based cross-sectional study. The sample size was 340. Data was collected by a predesigned pretested proforma to know about different risk factors. Fasting capillary blood glucose and 2h capillary blood glucose were taken to assess diabetes mellitus...
December 24, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28065464/lipid-metabolism-in-patients-with-chronic-hyperglycemia-after-an-episode-of-acute-pancreatitis
#8
Nicola A Gillies, Sayali A Pendharkar, Ruma G Singh, Varsha M Asrani, Maxim S Petrov
BACKGROUND: The importance of dyslipidemia is well recognized in the context of both risk factor for acute pancreatitis and prognostic factor for its in-hospital outcomes. With a growing appreciation of post-pancreatitis diabetes mellitus, there is a need to catalogue changes in lipid metabolism after hospitalization due to an acute pancreatitis attack and their associations with glucose metabolism. OBJECTIVE: To investigate lipid metabolism in patients with impaired glucose homeostasis following acute pancreatitis...
December 23, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28043815/associations-among-insulin-resistance-triacylglycerol-high-density-lipoprotein-tag-hdl-ratio-and-thyroid-hormone-levels-a-study-on-type-2-diabetes-mellitus-in-obese-and-overweight-subjects
#9
Rajendran Jayanthi, Abu Raghavan Srinivasan, Mohammed Hanifah, Anandraj Lokesh Maran
AIM: Triacylglycerol/High density lipoprotein (TAG/HDL) ratio, a surrogate marker of LDL particle size (small dense) was included in our study to observe the link with insulin resistance and thyroid co-morbidity. METHODS: Ninety three patients with T2DM of both genders were enrolled from a tertiary health care unit in Puducherry, during the latter half of 2015. The cardio-metabolic risk factors were assessed through body mass index (BMI), blood pressure, fasting blood glucose and lipid profile, glycated haemoglobin and homeostasis model assessment of insulin resistance (HOMA-IR)...
December 23, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28041921/rising-trend-of-diabetes-mellitus-amongst-the-undernourished-state-of-the-art-review
#10
REVIEW
Nimmy K Francis, Harpreet S Pawar, Anirban Mitra, Analava Mitra
Diabetes mellitus is prevailing in the malnourished populations congruently in well-nourished ones with an escalating trend in the former group regardless of the absence of obesity as an etiologic determining factor as per the studies in underprivileged sectors of the population. Chronic undernutrition across a lifetime may be an imperative stimulator of diabetes in an individual either by progressively reducing beta cell function alongside islet cell volume and increasing the individual predisposition to other genetic or environmental diabetogenic influences with modifying influence on the course of clinical syndrome...
December 23, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28057506/patient-perspectives-on-peripheral-neuropathic-pain-experience-within-the-community
#11
Devada Singh-Franco, Robin J Jacobs
Purpose of this cross-sectional study was to explore the relationship between neuropathic physical complaints (NPC) and quality-of-life (QoL) in community-dwelling patients with diabetes in Broward County, Florida. Adult patients were invited to complete a 10-minute paper questionnaire at a community hospital between October 2014-April 2016. Analysis of data from 124 participants (60 with distal symmetric polyneuropathy (DSPN) diagnosis versus 64 without DSPN diagnosis) with NPC, showed those with DSPN had a longer duration of diabetes, suffered a higher number of NPC, and had a lower QoL (all p≤0...
December 22, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28034693/distance-education-and-diabetes-empowerment-a-single-blind-randomized-control-trial
#12
Vahid Zamanzadeh, Mohammad Zirak, Masomeh Hemmati Maslakpak, Naser Parizad
AIMS: Diabetes is one of the biggest problems in healthcare systems and kills many people every year. Diabetes management is impossible when only utilizing medication. So, patients must be educated to manage their diabetes. This study aims to assess the effect of education by telephone and short message service on empowering patients with type 2 diabetes (primary outcome). MATERIALS AND METHODS: A single-blind randomized controlled trial was conducted in the Urmia diabetes association in Iran...
December 21, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28057505/prevalence-of-thyroid-dysfunction-among-type-2-diabetes-mellitus-patients
#13
M V Jali, Sanjay Kambar, Sujata M Jali, Nandita Pawar, Prachi Nalawade
AIMS: To determine the prevalence of Thyroid dysfunction among Type 2 Diabetes mellitus. METHODOLOGY: A cross-sectional hospital-based study is conducted to find out the prevalence of thyroid dysfunction. 713 type 2 diabetes mellitus (T2DM) subjects were enrolled in the survey. These subjects were investigated for fasting blood sugar (FBS), glycosylated haemoglobin (HbA1c), total triiodothyronine (T3), total thyroxine (T4), and thyroid-stimulating hormone (TSH)...
December 19, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28024831/impact-of-a-comprehensive-intervention-to-families-with-teenage-sons-with-overweight-and-obesity-in-a-primary-care-setting-a-case-report
#14
Alma Delia Laguna-Alcaraz, Oliva Mejía-Rodríguez, Ana Luisa Rendón-Paredes, Rafael Villa-Barajas, Ramón Paniagua
BACKGROUND: Overweight and obesity in adolescence is a public health problem and a risk factor for chronic noncommunicable diseases. To prevent further diseases, preventive interventions are needed, including educational programmes, addressed in a primary care setting, that include the whole family. The objective of this study was to evaluate the impact of a comprehensive intervention, targeting families with teenage sons with overweight and obesity, in the lifestyle, cardiovascular risk factors and metabolic syndrome in a primary care setting...
December 19, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28017633/complement-3-serum-levels-as-a-pro-inflammatory-biomarker-for-insulin-resistance-in-obesity
#15
REVIEW
Reem M Al Haj Ahmad, Hayder A Al-Domi
INTRODUCTION: Obesity is frequently characterized by chronic inflammation and insulin resistance (IR). Obesity-associated inflammation is responsible for the complement system activation of which the third component (C3) plays the central role. OBJECTIVE: to discuss several aspects of the central component of the complement system in relation to obesity and obesity-associated IR. METHODS: A critical review of the relevant published English articles from 2003- 2014 was carried out using several search engines including PubMed, Google Scholar, and ScienceDirect...
December 19, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28089167/diabetic-self-care-practices-in-rural-mysuru-southern-karnataka-india-a-need-for-diabetes-self-management-educational-dsme-program
#16
K M Srinath, Madhu Basavegowda, Nandarula Sai Tharuni
CONTEXT: Diabetes and its complications are the leading cause of morbidity and mortality in the world. Self care has emerged as a crucial element in the management of diabetes and a key factor associated with the quality of diabetic care. AIMS: The purpose of the study was to assess the self care activities of patients with Type II diabetes mellitus in a rural area of Mysuru district. SETTINGS AND DESIGN: A community based cross sectional descriptive study was carried out among 400 diabetic patients in rural Mysore...
December 15, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28024832/increased-waist-circumference-is-the-main-driver-for-the-development-of-the-metabolic-syndrome-in-south-african-asian-indians
#17
Rosaley Prakaschandra, Datshana P Naidoo
: There is no current evidence available on the prevalence of metabolic syndrome (MetS) in South African Asian Indians, who are at high risk for cardiovascular disease. The aim of our study was to determine the prevalence of the MetS in this group, between males and females, as well as in the different age-groups, using the harmonised criteria and determined the main components driving the development of MetS. DESIGN AND METHODS: This cross-sectional study recruited randomly selected community participants between the ages of 15 and 65 years, in the community of Phoenix, in KwaZulu-Natal...
December 15, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28024830/relationship-between-metabolic-syndrome-and-its-components-with-bone-densitometry-in-postmenopausal-women
#18
Mahnaz Abbasi, Seyed Amir Farzam, Zahra Mamaghani, Zohreh Yazdi
BACKGROUND: Prevention of osteoporosis and bone fracture and the relationship between metabolic syndrome and bone density are controversial issues. THE AIM OF THIS STUDY: The aim of this study was to evaluate the association between metabolic syndrome and its components with bone mineral density in post menopausal women referred for bone mineral density (BMD) test. METHODS: A total of 143 postmenopausal women with at least one year of menopause experience participated in this cross-sectional study...
December 15, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28017632/relationship-between-plasma-osteocalcin-glycaemic-control-and-components-of-metabolic-syndrome-in-adult-nigerians-with-type-2-diabetes-mellitus
#19
Chinelo P Onyenekwu, Elaine C Azinge, Ephraim U Egbuagha, Henry C Okpara
AIMS: To determine the levels of plasma osteocalcin (OC) in Nigerians with type 2 diabetes mellitus (DM) and compare these to levels in non-diabetic controls (NDM). To assess the relationship of OC to glycaemic control and parameters of metabolic syndrome (MetS) and compare its levels in Nigerians with and without MetS. METHODS: The waist circumference (WC), body mass index (BMI) and blood pressure of 200 study participants were taken. Plasma osteocalcin, fasting glucose (FPG), glycated haemoglobin (HbA1c), high density lipoprotein cholesterol (HDL-c) and triglyceride (TG) levels were determined...
December 15, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28017631/nonalcoholic-fatty-liver-disease-and-the-risk-of-clinical-cardiovascular-events-a-systematic-review-and-meta-analysis
#20
REVIEW
Toufik Mahfood Haddad, Shadi Hamdeh, Arun Kanmanthareddy, Venkata M Alla
OBJECTIVE: Numerous studies have assessed the association between Nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease (CVD). However, results have been conflicting due to variability in definitions of NAFLD and ascertainment of CVD, often combining clinical and surrogate endpoints. We therefore systematically reviewed published literature to assess the association between NAFLD and clinical cardiovascular events (CVE) and performed a meta-analysis. METHODS: We searched PubMed, Medline, Cochrane, CINAHL, and Web of Science databases using terms "nonalcoholic fatty liver disease", "nonalcoholic steatohepatitis", "cardiovascular disease", and their combinations to identify prospective studies published from inception through March 2016...
December 15, 2016: Diabetes & Metabolic Syndrome
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