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Diabetes & Metabolic Syndrome

Supriya Mishra, Vani Gupta, Sameeksha Mishra, Himani Kulshrestha, Sandeep Kumar, Vandana Gupta, Rekha Sachan, Abbas Ali Mahdi
BACKGROUND: Plasma concentrations of Acylation stimulating protein (ASP) and adiponectin are associated with body weight and energy homeostasis. The purpose of this study is to describe the potential role of acylation stimulating protein and adiponectin with metabolic risk marker in North Indian obese women. METHODS: This is a case control study. Total 520 women were recruited for the study n = 260 women with obesity (BMI>30) study group and n = 260 women without obesity (BMI<25) control group...
July 30, 2018: Diabetes & Metabolic Syndrome
Nazila Kassaian, Awat Feizi, Ashraf Aminorroaya, Masoud Amini
AIMS: Modulation of the gastrointestinal microbiome is suggested to contribute to the progression of metabolic syndrome associated diseases. This study was designed to assess the effects of probiotics and synbiotics on metabolic syndrome in individuals with prediabetes. METHODS: 120 adults with prediabetes were enrolled in a double-blind, placebo-controlled randomized parallel-group clinical trial. Participants were randomized to a multi-species probiotic or inulin-based synbiotic or placebo...
July 30, 2018: Diabetes & Metabolic Syndrome
Samreen Siddiqui, Swati Waghdhare, Sujeet Jha, Shweta Dubey
Gestational Diabetes Mellitus (GDM) is a condition which develops due to insulin resistance. There are a number of immunological markers (IL-6, TNF-α, IL-10, etc), which play significant role during normal pregnancy and their irregular levels could likely cause some level of insulin resistance. There are studies which have compared the levels of different immunological mediators in GDM affected females and their healthy controls, but their findings are little controversial. Some of the studies have reported increased levels of IL-6, TNF-α, adiponectin, leptin, in females affected with GDM, while others do not confirm this...
July 30, 2018: Diabetes & Metabolic Syndrome
Maryna Neborachko, Aleksandr Pkhakadze, Iryna Vlasenko
Industry 4.0 is an updated concept of smart production, which is identified with the fourth industrial revolution and the emergence of cyber-physical systems. Industry 4.0 is the next stage in the digitization of productions and industries, where such technologies and concepts as the Internet of things, big data, predictive analytics, cloud computing, machine learning, machine interaction, artificial intelligence, robotics, 3D printing, augmented reality. As an area of therapy with the best market potential and one of the most expensive global diseases, diabetes attracts the best healthcare players, who use innovative technologies...
July 29, 2018: Diabetes & Metabolic Syndrome
Joane Diomara Coleone, Ericles Andrei Bellei, Ana Carolina Bertoletti De Marchi
AIMS: To map and discuss the different methods used to assess food consumption and glycemic testing of adults and elderly diabetic patients from Public Health. MATERIALS AND METHODS: A total of 710 records were identified by searching databases integrated by the Virtual Health Library website, between September and October 2017. The Newcastle Ottawa scale was used for study quality assessment. A total of 8 studies met inclusion criteria for analysis. Study characteristics were extracted and synthesized to generate comparisons...
July 19, 2018: Diabetes & Metabolic Syndrome
Omar Farooq Nafea Al-Azzawi, Manal Khudder Abdul Razak, Sura Jabbar Al Hammady
BACKGROUND: Rhabdomyolysis is considered by some studies as a rare complication of a common disorder of diabetic ketoacidosis, while others consider it as not so uncommon. The mechanism is still not clear but can be attributed to a number of factors like acidosis, hyperglycemia and electrolyte disturbances especially hypophosphatemia and hypokalaemia. Missing it may lead to more serious complications and may prolong and/or complicate full recovery of diabetic ketoacidosis. AIM: The aim of this study was to measure the incidence of rhabdomyolysis among patients presented with diabetic ketoacidosis in the emergency department of Baghdad Teaching hospital, its relation to the severity of diabetic ketoacidosis and the associated electrolytes disturbances...
July 19, 2018: Diabetes & Metabolic Syndrome
Nilupher, Meenal Dhall, Satwanti Kapoor
OBJECTIVES: This study aims to find out the association of lifestyle with adiposity markers among the patients with diabetes. MATERIALS AND METHODS: 200 diabetic participants of both sexes were enrolled in the present study. Age group of the participants ranged from 20 years to 45 years. A cross sectional study was conducted for the present study. Data was collected from Imphal East district and Thoubal district of Manipur. OBSERVATIONS: The study reported maximum percentage of overweight BMI among diabetic females as compared to diabetic males...
July 17, 2018: Diabetes & Metabolic Syndrome
Gaya W Katulanda, Harsha A Dissanayake, Prasad Katulanda, David R Matthews, Brian Shine
AIMS: Metabolic syndrome (MetS) is a risk factor for cardiovascular disease (CVD). Apolipoproteins are emerging as powerful predictors of CVD. We aimed to study associations of metabolic syndrome and apoB, apoAI, apoB/AI ratio in young Sri Lankans with type 2 diabetes. MATERIALS & METHODS: Blood samples were available from 690 patients with type 2 diabetes in Sri Lanka Young Diabetes Study, and were analysed for apoB, apoAI, total cholesterol (TC), high-density lipoprotein cholesterol (HDLC), triglycerides (TG) and glycated haemoglobin (HbA1c )...
July 17, 2018: Diabetes & Metabolic Syndrome
G K Mini, P S Sarma, K R Thankappan
AIM: To determine the prevalence and associated risk factors of metabolic syndrome (MS) among industrial workers in Kerala, India. MATERIALS AND METHODS: We measured fasting plasma glucose (FPG), triglycerides, high density lipoprotein cholesterol, waist circumference, systolic blood pressure and diastolic blood pressure among 2287 industrial workers (mean age 46 years, men 70%) from selected industries of two southern most Kerala districts using standard protocol in 2009...
July 17, 2018: Diabetes & Metabolic Syndrome
Kaisun Nesa Lesa, Tanvir Ahmed Siddikey
OBJECTIVES: The present study aimed to evaluate the Impact of heart disease risk factors on the age of 30-80 years' old patients-residing in and around Khulna District of Bangladesh. Data collection took place in April, 2017 to October, 2017. METHODS: The research was characterized by questionnaires on the basis of gender, age, BMI, physical activity, working pattern, family history, fast food consumption, smoking habit and Total cholesterol test. The population sample consisted of 240 patients were selected randomly for collection of data who were diagnosis by heart disease...
July 17, 2018: Diabetes & Metabolic Syndrome
Alexander Berezin
Diabetes mellitus (DM) is the most important metabolic disease with major threat for public health and increased risk of premature death. The prevalence of DM steadily rises in developing and developed countries achieving the epidemic level. Manifestation and progression of DM corresponds to developing vasculopathies, such as retinopathy, micro- and macro angiopathies, which negatively influence on clinical outcomes and quality-of-life. Although there are remarkable differences in the prevalence of vasculopathy in various types of DM, hyperglycemia and lipotoxicity are discussed as a major factors contributing to vascular complications partly through inducing neutrophil extracellular trap (NET)...
July 17, 2018: Diabetes & Metabolic Syndrome
Priscila de Oliveira Siciliano, Amelio F Godoy-Matos, Letícia Dinis da C Braga, José Denise Pires Carvalho, José Otávio do Amaral Corrêa
AIMS: Dipeptidyl peptidase-4 (DPP4) is a new adipokine increased in central obesity and related to insulin resistance (IR). Postmenopausal (PM) state may be associated with increase in body weight and central fat distribution. We hypothesize that DPP4 is increased in PM women. MATERIALS AND METHODS: Twenty-two non-obese PM and 22 non-obese premenopausal women (PreM), were evaluated. DPP4 activity, lipid profile, HbA1c, FSH, estradiol and sex hormone-binding globulin (SHBG) were measured; an oral glucose tolerance test (OGTT) was performed and IR calculated...
July 17, 2018: Diabetes & Metabolic Syndrome
David M Walton, Stephen D Minton, Alonzo D Cook
The Center for Disease Control (CDC) estimates that 29 million Americans have diabetes, and 70% of diabetic patients develop diabetic peripheral neuropathy [1,2]. Up to 27% of the direct medical cost of diabetes may be attributed to DPN [3]. A 2013 article from the American Diabetes Association reported a $176 billion direct medical cost of diabetes in 2012 [4]. DPN patients often suffer from shooting and burning pain in their distal limbs and a severe loss of sensation. Diabetic foot ulcers, infections, and amputations may follow...
July 17, 2018: Diabetes & Metabolic Syndrome
Najmeh Manshaei, Feloria Shakibaei, Mohammad Fazilati, Hossein Salavati, Masoud Negahdary, Abbasali Palizban
As a hormone secreted from the pituitary gland, prolactin (PRL) plays an important role in increasing beta cell proliferation, stimulating the secretion of insulin, preventing the activities of caspases on pathways that cause apoptosis in the Langerhans' islands, and moderating the immune system in regulating the whole body's sensitivity to insulin. Therefore, PRL level changes in type II diabetes and it can be concluded that PRL can play an important role in metabolic disorders of glucose. The present study is carried out in order to investigate the association between serum levels of PRL and type II DM...
July 17, 2018: Diabetes & Metabolic Syndrome
Rashmi B Prasad, Emma Ahlqvist, Leif Groop
No abstract text is available yet for this article.
July 11, 2018: Diabetes & Metabolic Syndrome
Firass Abiad, Dalia Khalife, Bassem Safadi, Ramzi Alami, Johnny Awwad, Fatin Khalifeh, Ghina Ghazeeri
AIM: The aims of this study is to address the improvement in CRP and adiponectin in obese PCOS and non PCOS after bariatric surgery, and to show that obese PCOS women have a slower rate of improvement when compared to obese non PCOS women. METHODS: This is a prospective case-control study evaluating the effect of weight loss by sleeve gastrectomy among obese PCOS patients. RESULTS: There was a 36.28% of weight loss among obese PCOS and 33...
November 2018: Diabetes & Metabolic Syndrome
Anneh Mohammad Gharravi, Alireza Jafar, Mehrdad Ebrahimi, Ahmad Mahmodi, Erfan Pourhashemi, Nasrin Haseli, Niloofar Talaie, Parinaz Hajiasgarli
Diabetes mellitus (DM) remains the 7th leading cause of death in the world. Daily insulin injection is one component of a treatment plan for people with Diabetes mellitus type 1 (T1DM) that restores normal or near-normal blood sugar levels. However, Insulin treatment depends upon a variety of individual factors and leads to poor and drastic glycemic control. The need for an effective cell replacement strategy will be the aim of future clinical trials. Therefore, the aim of this systematic review is to outline the latest advances in scaffolding and stem cell therapy as a non-pharmacologic treatment for T1DM...
November 2018: Diabetes & Metabolic Syndrome
Yasser Mostafa Hafez, Omnia Safwat El-Deeb, Marwa Mohamed Atef
BACKGROUND: Diabetic foot ulceration (DFU) is a serious diabetic complication that can progress to amputation and since SIRT1 regulates glucose metabolism, inflammation, and oxidative stress which are the major contributors in diabetic complications, So we aimed to discuss its role as an epigenetic biomarker in DFU and highlight its link to oxidative stress and inflammatory cytokines. METHOD: 60 DM patients were enrolled in the study, 30 without DFU and 30 with DFU in addition to 15 healthy subjects (control group)...
November 2018: Diabetes & Metabolic Syndrome
Tarek Mohamed Ali, Ahmad El Askary
BACKGROUND: Inconsistent results have been described regarding the part of fetuin-A and testosterone in arterial stiffness in type 2 diabetes mellitus (T2DM). AIM: To look into the links of serum fetuin-A and testosterone levels with brachial-Ankle pulse wave velocity (baPWV), a marker of arteriosclerosis and common carotid intima media thickness (ccIMT), a marker of early atherosclerosis, in diabetic Saudi men patients. SUBJECTS AND METHODS: One hundred and fifty adult male patients with T2DM and 60 non-diabetic control subjects were enrolled from different Saudi Arabia Taif hospitals...
November 2018: Diabetes & Metabolic Syndrome
Leila Yazdanpanah, Hajieh Shahbazian, Iraj Nazari, Saeed Hesam, Fatemeh Ahmadi, Bahman Cheraghian, Hamid Reza Arti, Seyed Ehsan Mohammadianinejad
AIMS: This study was done to assess the risk factors associated with diabetic foot ulcer-free survival in patients with diabetes. MATERIALS AND METHODS: Based on a prospective cohort study, ADFC (Ahvaz Diabetic Foot Cohort) study, carried out in a university hospital, all of the patients with diabetes were followed up for new diabetic foot ulcer (DFU). The time of ulcer development was final outcome during two years in the present study. To analyze the data, the variables were first evaluated by univariate analysis...
November 2018: Diabetes & Metabolic Syndrome
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