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Diabetes & Metabolic Syndrome

Masoume Mansouri, Roshanak Abasi, Morteza Nasiri, Farshad Sharifi, Sedyghe Vesaly, Omid Sadeghi, Nayere Rahimi, Nasrin Akbary Sharif
AIM: We aimed to assess the association of vitamin D status with metabolic syndrome and its components among high educated Iranian adults. METHOD: In this cross-sectional study, 352 faculty members with age of 35 years or more, belong to Tarbiat Modares University, Tehran, Islamic Republic of Iran, were recruited during 2016 and 2017. Fasting blood samples were obtained to quantify serum 25(OH)D concentrations, glycemic indicators and lipid profile. Metabolic syndrome was defined based on the guidelines of the National Cholesterol Education Program Adult Treatment Panel III (ATP III)...
February 1, 2018: Diabetes & Metabolic Syndrome
Abdul Hakeem Alrawahi, Patricia Lee
AIM: The first cardiovascular risk prediction model in the Arab world was recently developed for Omanis with type 2 diabetes mellitus. This study aims to validate the newly developed model. MATERIALS AND METHODS: A retrospective cohort study design was applied in this study. The model was validated in two samples; the model derivation sample and a separate validation sample, consisting of 1314 and 405 diabetics respectively. All patients were free of cardiovascular disease at the baseline (2009-2010) and were followed up until: the first cardiovascular event occurred; the patient died; or up to December 2015...
February 1, 2018: Diabetes & Metabolic Syndrome
Sivabal Vanjiappan, Abdoul Hamide, Ramesh Ananthakrishnan, Senthilkumar Gandhipuram Periyasamy, Vadivelan Mehalingam
INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of liver disease that ranges from hepatic steatosis to non-alcoholic steatohepatitis. Obesity and diabetes mellitus are the prime risk factors for NAFLD. The aim of this study was to find out the prevalence of NAFLD among patients with type 2 diabetes mellitus and to detect the association of NAFLD with cardiovascular disease in them. STUDY DESIGN: Prospective observational study...
January 31, 2018: Diabetes & Metabolic Syndrome
Alok Raghav, Jamal Ahmad, Saba Noor, Khursheed Alam, Brijesh Kumar Mishra
AIM: Glycated albumin (GA) suggested being alternative glycemic marker than haemoglobin A1C (HbA1c) in patients with chronic kidney diseases (CKD). We investigated the association between GA and the progression of diabetic nephropathy (DN) in T2DM subjects. METHODS: We recruited T2DM subjects with different stages of CKD who had regularly measured serum creatinine and estimated glomerular filtration rates (eGFR) according to Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines, HbA1c consecutively every 3 months along with GA levels and other anthropometric and demographic measurements...
January 30, 2018: Diabetes & Metabolic Syndrome
Alok Raghav, Jamal Ahmad
Nephropathy in diabetes patients is the most common etiology of end-stage kidney disease (ESKD). Strict glycemic control reduces the development and progression of diabetes-related complications, and there is evidence that improved metabolic control improves outcomes in subjects having diabetes mellitus with advanced chronic kidney disease (CKD). Glycemic control in people with kidney disease is complex. Changes in glucose and insulin homoeostasis may occur as a consequence of loss of kidney function and dialysis...
January 30, 2018: Diabetes & Metabolic Syndrome
Muhammad Bilal, Abdul Haseeb, Abdur Rehman
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting women of reproductive age. The two main documented pathogenic mechanisms are hyperinsulinemia and hyperandrogenemia but there is growing evidence for increased predisposition to cardiovascular disease, dyslipidemia, and type 2 diabetes mellitus. Our study aims to analyze the association of PCOS with cardiovascular risk factors. METHODS: This is a prospective study which targeted 100 PCOS patients from Civil Hospital Karachi over a period of one year (July 2016 to July 2017)...
January 27, 2018: Diabetes & Metabolic Syndrome
Sharmin Mahbuba, Fauzia Mohsin, Farhana Rahat, Jebun Nahar, Tahmina Begum, Nazmun Nahar
AIMS: The study was done to assess the magnitude of problems of metabolic syndrome among obese adolescents. MATERIALS AND METHOD: It was a cross-sectional study done from January 2013 to June 2014 in paediatric endocrine outpatient department in BIRDEM General Hospital, Dhaka, Bangladesh. Total 172 adolescents having exogenous obesity aged 10-18 years were included. Impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and type 2 diabetes mellitus (DM) were defined as per WHO criteria...
January 4, 2018: Diabetes & Metabolic Syndrome
Meryem Abi-Ayad, Amine Abbou, Fatima Zahra Abi-Ayad, Omar Behadada, Mohamed Benyoucef
AIM: Hypercholesterolemia and hyper LDL-C are associated with the atherosclerosis (AS). The current study was performed to evaluate the implication of the others lipoproteins (HDL, LDL, VLDL) and apolipoproteins (ApoA1, ApoB100) with subclinical atherosclerosis (carotid plaque) in patients with metabolic syndrome (MetS) free from cardiovascular disease (CVD). METHODS: Prospective transversal study was conducted in patients with MetS free from cardiovascular disease (CVD)...
December 30, 2017: Diabetes & Metabolic Syndrome
Roy Robson, Avinash R Kundur, Indu Singh
AIMS: Type-2 Diabetes Mellitus (T2DM) is one of the most prevalent and progressive metabolic conditions affecting approximately 8.5% of the global population. Individuals with T2DM have a significantly increased risk of developing chronic conditions such as cardiovascular disease (CVD) and its associated complications, therefore, it is of great importance to establish strategies for combatting T2DM and its associated chronic conditions. Current literature has identified several biomarkers that are known to play a key role in the pathogenesis of CVD...
December 30, 2017: Diabetes & Metabolic Syndrome
Basma Damiri, Amir Aghbar, Saja Alkhdour, Yousef Arafat
OBJECTIVES: Metabolic Syndrome "MetS" is characterized by the presence of several factors that play a major role in the development of cardiovascular diseases and diabetes mellitus. This study was conducted to establish the prevalence of MetS and its individual components among the overweight and obese students at An-Najah National University (ANU) using IDF and modified NCEP ATP III definition and to identify conditions associated with it. MATERIALS AND METHODS: A cross-sectional study was conducted in 2016...
December 30, 2017: Diabetes & Metabolic Syndrome
Hiba S Al-Amodi, Nazik Altayeb Abdelbasit, Samir H Fatani, Abdullatif Taha Babakr, Maowia Mohamed Mukhtar
BACKGROUND: Leptin levels are reported to be increased with excessive body fat and is a potential determinant of obesity and its complications. Our Objective is to evaluate the relationship between leptin levels and BMI, waist circumference and metabolic syndrome components in normal and obese females classified according to their BMI. SUBJECTS AND METHODS: A total of 136 female subjects aged between 20 and 60 years were recruited for the current study. Anthropometric measures included body mass index and waist circumference...
December 29, 2017: Diabetes & Metabolic Syndrome
Zahra Karimi, Farima Kahe, Adeel Jamil, Jolanta Marszalek, Asiye Ghanbari, Mohsen Afarideh, Elias Khajeh, Sina Noshad, Alireza Esteghamati, Gerald Chi
BACKGROUND: Nephropathy is a major complication of type 2 diabetes mellitus (T2DM) and is heralded by the insidious development of microalbuminuria (MA). It is suggested that the serum levels of Intercellular Adhesion Molecule-1 (ICAM-1) is correlated with diabetic nephropathy. In this cross-sectional study, we evaluated serum ICAM-1 level in diabetic patients with and without MA. METHODS: A total of 187 participants were enrolled and were classified into three groups including 40 healthy controls and 2 diabetic groups with (n = 59) or without MA (n = 88)...
December 28, 2017: Diabetes & Metabolic Syndrome
Sueziani B Zainudin, Aslena B Hussain
AIMS: Obligatory Ramadan fasting is challenging in the management of Muslims with diabetes due to increased risk of complications from altered meals and activities. This study aimed to evaluate the knowledge, perception and practice of healthcare professionals in diabetes management during fasting and the outcome of education on management. MATERIALS AND METHODS: We surveyed healthcare professionals enrolled in pre-Ramadan education involving an endocrinologist, diabetes specialized nurse and dietician...
December 28, 2017: Diabetes & Metabolic Syndrome
Yaser Mokhayeri, Seyed Mohammad Riahi, Shadi Rahimzadeh, Mohammad Amin Pourhoseingholi, Seyed Saeed Hashemi-Nazari
AIMS: Metabolic syndrome (MetS) is one of the most important predictors of CVD. Determining the trend of MetS, represents the trend of its components and consequently could forecast the incidence of related diseases particularly CVD. The main object of this study is describing the trend of MetS prevalence in both male and female. MATERIALS AND METHODS: Original research studies from March 21, 2005 to March 20, 2015 that were published in English database and Persian databases were included in the systematic review...
December 23, 2017: Diabetes & Metabolic Syndrome
Deepak Gahlan, Rajesh Rajput, Pratibha Gehlawat, Rajiv Gupta
BACKGROUND: Patients of diabetes mellitus experience psychological difficulties associated with their disease which remains unrecognized involving several states related to coping with diabetes. Diabetes distress is a distinct condition which is often mistaken for depression and is related to adverse disease outcomes. AIMS AND OBJECTIVE: To study the prevalence and predictors of diabetes distress in patients of Type 2 Diabetes mellitus (T2DM) in a tertiary care centre...
December 22, 2017: Diabetes & Metabolic Syndrome
Leonardo M Porchia, M Elba Gonzalez-Mejia, Enrique Torres-Rasgado, Guadalupe Ruiz-Vivanco, Ricardo Pérez-Fuentes
AIM: Insulin and uric acid were shown affect the prevalence of Metabolic Syndrome (MetS), but no studies examine their interaction. Therefore, we conducted this study to determine their biological interaction in subjects from central Mexico. METHODS: 433 subjects were enrolled for a cross-sectional study. MetS was defined according to the Harmonizing Definition. Hyperuricemia was defined as ≥7.0 mg/dL in males and ≥5.8 mg/dL in females. Hyperinsulinemia was defined as ≥11...
December 22, 2017: Diabetes & Metabolic Syndrome
Sedigheh Nouhjah, Hajieh Shahbazian, Nahid Shahbazian, Shayesteh Jahanfar, Alireza Jahanshahi, Bahman Cheraghian, Zeinab Dehghan Mohammadi, Niloofar Ghodrati, Sousan Houshmandi
AIMS: This study aimed to determine the prevalence rate of metabolic syndrome and its potential risk factors, 6-12 weeks postpartum in women with GDM compared to women with normal glucose tolerance. METHODS: LAGAs is an ongoing population-based prospective cohort study that started in March 2015 in Ahvaz, Iran. During 11 months of study progression, 176 women with GDM pregnancy and 86 healthy women underwent a fasting glucose test, 75-g OGTT and fasting lipid tests at 6-12 weeks postpartum...
December 22, 2017: Diabetes & Metabolic Syndrome
M Aslam, A A Siddiqui, G Sandeep, S V Madhu
AIM: To find out the prevalence of obesity and glucose intolerance among nurses working in tertiary care hospital. METHODS: Study was conducted in 496 apparently healthy females comprising two groups. Group B had 290 nurses and control group A had 206 age matched female subjects of general population. Detailed performa was filled which included anthropometry, systemic examination and other details. Fasting plasma glucose was done followed by oral glucose tolerance test (OGTT)...
December 22, 2017: Diabetes & Metabolic Syndrome
Reza Tabrizi, Kamran B Lankarani, Maryam Akbari, Ahmad Naghibzadeh-Tahami, Hosniyeh Alizadeh, Behnam Honarvar, Nasrin Sharifi, Majid Mazoochi, Vahidreza Ostadmohammadi, Asadolah Fatholahpour, Zatollah Asemi
BACKGROUND AND OBJECTIVE: Although several studies have assessed the effect of folate supplementation on lipid profiles among patients with metabolic diseases, findings are inconsistent. This review of randomized controlled trials (RCTs) was conducted to summarize the evidence on the effects of folate supplementation on lipid profiles among patients with metabolic diseases. METHODS: Randomized-controlled trials (RCTs) published in PubMed, EMBASE, Web of Science and Cochrane Library databases up to until 20 August 2017 were searched...
December 22, 2017: Diabetes & Metabolic Syndrome
Youssouf Kachekouche, Madjda Dali-Sahi, Djamel Benmansour, Nouria Dennouni-Medjati
BACKGROUND: Hematological changes affecting blood cells and the coagulation factors are shown to be associated with diabetes mellitus. We investigated some of the hematological risk factors implicated in the development of type 2 diabetes mellitus. METHODS: The study conducted in western Algeria on a sample of 1852 subjects, 1059 with type 2 diabetes and 793 witnesses, were evaluated for peripheral blood parameters using hematology analyzer. All the informations related to the disease were collected from the patients and recorded using predesigned questionnaire...
December 21, 2017: Diabetes & Metabolic Syndrome
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