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Autism Research: Official Journal of the International Society for Autism Research

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https://www.readbyqxmd.com/read/29979494/emotion-regulation-in-autism-spectrum-disorder-where-we-are-and-where-we-need-to-go
#1
Ru Ying Cai, Amanda L Richdale, Mirko Uljarević, Cheryl Dissanayake, Andrea C Samson
Emotion dysregulation is a common issue experienced by individuals with autism spectrum disorder (ASD) and has been associated with a wide range of negative mental and physical health outcomes. This commentary highlights the role emotion dysregulation plays in ASD by first considering the literature on emotion regulation (ER) in the general population and then summarizing the ER research in ASD. Based on the evaluation of previous research findings, we conclude that individuals with ASD have more ER difficulties and consistently self-report or demonstrate a less adaptive pattern of ER strategy use...
July 6, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29979489/happiness-self-esteem-and-prosociality-in-children-with-and-without-autism-spectrum-disorder-evidence-from-a-uk-population-cohort-study
#2
Gillian McChesney, Umar Toseeb
High levels of childhood happiness, self-esteem, and prosociality are associated with positive social and emotional outcomes. Little is known about whether these constructs co-occur and how levels of co-occurrence are different in children with or without Autism Spectrum Disorder (ASD). Data was obtained from 13,285 11-year olds (408 with ASD) from a UK based prospective cohort study. Latent class analysis revealed five distinct classes: The "very low prosociality class" (with ASD 32% vs. without ASD 7%) was characterized by children who were happy and had high self-esteem but they were not prosocial...
July 6, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29761934/assessing-the-heterogeneity-of-autism-spectrum-symptoms-in-a-school-population
#3
Paula Morales-Hidalgo, Pere J Ferrando, Josefa Canals
The aim of the present study was to assess whether the nature of the main autistic features (i.e., social communication problems and repetitive and restrictive patterns) are better conceptualized as dimensional or categorical in a school population. The study was based on the teacher ratings of two different age groups: 2,585 children between the ages of 10 and 12 (Primary Education; PE) and 2,502 children between the ages of 3 and 5 (Nursery Education; NE) from 60 mainstream schools. The analyses were based on Factor Mixture Analysis, a novel approach that combines dimensional and categorical features and prevents spurious latent classes from appearing...
May 15, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29761862/cellular-stress-and-apoptosis-contribute-to-the-pathogenesis-of-autism-spectrum-disorder
#4
Daoyin Dong, Horst Ronald Zielke, David Yeh, Peixin Yang
The molecular pathogenesis of autism spectrum disorder, a neurodevelopmental disorder, is still elusive. In this study, we investigated the possible roles of endoplasmic reticulum (ER) stress, oxidative stress, and apoptosis as molecular mechanisms underlying autism. This study compared the activation of ER stress signals (protein kinase R-like endoplasmic reticulum kinase [PERK], activating transcription factor 6 [ATF6], inositol-requiring enzyme 1 alpha [IRE1α]) in different brain regions (prefrontal cortex, hippocampus, cerebellum) in subjects with autism and in age-matched controls...
May 15, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29761854/parenting-adolescents-with-asd-a-multimethod-study
#5
Lotte van Esch, Steven Vanmarcke, Eva Ceulemans, Karla Van Leeuwen, Ilse Noens
A number of studies have concluded that parents of children with ASD experience high levels of parenting stress. However, little is known about their parenting behaviors. Especially few studies investigated parenting in adolescence, although this period is associated with additional challenges for both adolescents and their parents. In the present study, a multi-method approach was used, combining data from a self-report questionnaire and observation of mother-child interactions during different semi-structured (e...
May 15, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29761836/acceptability-and-caregiver-reported-outcomes-for-young-children-with-autism-spectrum-disorder-whose-parents-attended-a-preventative-population-based-intervention-for-anxiety-a-pilot-study
#6
Natalie L Bischof, Ronald M Rapee, Kristelle Hudry, Jordana K Bayer
This pilot study explored acceptability to parents and outcomes for children of a preventive intervention for anxiety problems in pre-schoolers with autism spectrum disorder (ASD) who were an identified sub-group within a population-based randomised trial of the Cool Little Kids parenting group programme. The population trial included 545 temperamentally inhibited pre-schoolers recruited across eight economically diverse areas of Melbourne, Australia. Within this sample, 26 parents reported that their child had received an ASD diagnosis...
May 15, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29734508/using-machine-learning-to-identify-patterns-of-lifetime-health-problems-in-decedents-with-autism-spectrum-disorder
#7
Lauren Bishop-Fitzpatrick, Arezoo Movaghar, Jan S Greenberg, David Page, Leann S DaWalt, Murray H Brilliant, Marsha R Mailick
Very little is known about the health problems experienced by individuals with autism spectrum disorder (ASD) throughout their life course. We retrospectively analyzed diagnostic codes associated with de-identified electronic health records using a machine learning algorithm to characterize diagnostic patterns in decedents with ASD and matched decedent community controls. Participants were 91 decedents with ASD and 6,186 sex and birth year matched decedent community controls who had died since 1979, the majority of whom were middle aged or older adults at the time of their death...
May 7, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29734507/screening-in-toddlers-and-preschoolers-at-risk-for-autism-spectrum-disorder-evaluating-a-novel-mobile-health-screening-tool
#8
Stephen M Kanne, Laura Arnstein Carpenter, Zachary Warren
There are many available tools with varying levels of accuracy designed to screen for Autism Spectrum Disorder (ASD) in young children, both in the general population and specifically among those referred for developmental concerns. With burgeoning waitlists for comprehensive diagnostic ASD assessments, finding accurate methods and tools for advancing diagnostic triage becomes increasingly important. The current study compares the efficacy of four oft used paper and pencil measures, the Modified Checklist for Autism in Toddlers Revised with Follow-up, the Social Responsiveness Scale, Second Edition, and the Social Communication Questionnaire, and the Child Behavior Checklist to a novel mobile-health screening tool developed by Cognoa, Inc...
May 7, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29734506/predictors-of-quality-of-life-for-autistic-adults
#9
David Mason, Helen McConachie, Deborah Garland, Alex Petrou, Jacqui Rodgers, Jeremy R Parr
Research with adults on the autism spectrum is as yet limited in scope and quality. The present study describes quality of life (QoL) of a large sample of autistic adults in the UK and investigates characteristics that may be predictive of QoL. A total of 370 autistic adults from the Adult Autism Spectrum Cohort-UK (ASC-UK) completed the WHOQoL-BREF, and the Social Responsiveness Scale (SRS, autism symptom severity), along with the ASC-UK registration questionnaire giving information on mental health and their life situation...
May 7, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29734504/typical-use-of-inverse-dynamics-in-perceiving-motion-in-autistic-adults-exploring-computational-principles-of-perception-and-action
#10
Shinya Takamuku, Paul A G Forbes, Antonia F de C Hamilton, Hiroaki Gomi
There is increasing evidence for motor difficulties in many people with autism spectrum condition (ASC). These difficulties could be linked to differences in the use of internal models which represent relations between motions and forces/efforts. The use of these internal models may be dependent on the cerebellum which has been shown to be abnormal in autism. Several studies have examined internal computations of forward dynamics (motion from force information) in autism, but few have tested the inverse dynamics computation, that is, the determination of force-related information from motion information...
May 7, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29727503/gender-differences-in-mental-rotation-strategy-depend-on-degree-of-autistic-traits
#11
Jennifer L Stevenson, Mary B Nonack
Participants with low, medium, and high autistic traits completed a mental rotation task while their eye movements were recorded. Men were more accurate than women (F(1, 102) = 4.36, P = 0.04, η2 p  = 0.04), but there were no group differences in reaction time. In terms of eye movements, all participants tended to rely on top corners of cube figures for most angles of rotation, and bottom corners of cube figures for 0 and 90 degree rotations (duration: F(8, 816) = 21.70, P < 0.001, η2 p  = 0...
May 4, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29701910/can-you-spot-a-liar-deception-mindreading-and-the-case-of-autism-spectrum-disorder
#12
David M Williams, Toby Nicholson, Catherine Grainger, Sophie E Lind, Peter Carruthers
Detection of deception is of fundamental importance for everyday social life and might require "mindreading" (the ability to represent others' mental states). People with diminished mindreading, such as those with autism spectrum disorder (ASD), might be at risk of manipulation because of lie detection difficulties. In Experiment 1, performance among 216 neurotypical adults on a realistic lie detection paradigm was significantly negatively associated with number of ASD traits, but not with mindreading ability...
April 27, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29693781/the-effect-of-physical-activity-interventions-on-youth-with-autism-spectrum-disorder-a-meta-analysis
#13
REVIEW
Sean Healy, Adam Nacario, Rock E Braithwaite, Chris Hopper
The purpose of this meta-analysis was to examine the effect of physical activity interventions on youth diagnosed with autism spectrum disorder. Standard meta-analytical procedures determining inclusion criteria, literature searches in electronic databases, coding procedures, and statistical methods were used to identify and synthesize articles retained for analysis. Hedge's g (1988) was utilized to interpret effect sizes and quantify research findings. Moderator and outcome variables were assessed using coding procedures...
April 25, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29878689/erratum-to-article-sensitivity-to-audio-visual-synchrony-and-its-relation-to-language-abilities-in-children-with-asd-autism-research-10-1002-aur-1918
#14
(no author information available yet)
No abstract text is available yet for this article.
May 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29573234/modeling-autism-in-non-human-primates-opportunities-and-challenges
#15
REVIEW
Hui Zhao, Yong-Hui Jiang, Yong Q Zhang
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social communication deficits and restricted, repetitive patterns of behavior. For more than a decade, genetically-modified, risk factor-induced, as well as naturally occurring rodent models for ASD have been used as the most predominant tools to dissect the molecular and circuitry mechanisms underlying ASD. However, the apparent evolutionary differences in terms of social behavior and brain anatomy between rodents and humans have become an issue of debate regarding the translational value of rodent models for studying ASD...
May 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29524310/onset-patterns-in-autism-variation-across-informants-methods-and-timing
#16
Sally Ozonoff, Devon Gangi, Elise P Hanzel, Alesha Hill, Monique M Hill, Meghan Miller, A J Schwichtenberg, Mary Beth Steinfeld, Chandni Parikh, Ana-Maria Iosif
While previous studies suggested that regressive forms of onset were not common in autism spectrum disorder (ASD), more recent investigations suggest that the rates are quite high and may be under-reported using certain methods. The current study undertook a systematic investigation of how rates of regression differed by measurement method. Infants with (n = 147) and without a family history of ASD (n = 83) were seen prospectively for up to 7 visits in the first three years of life. Reports of symptom onset were collected using four measures that systematically varied the informant (examiner vs...
May 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29517857/neural-mechanisms-of-behavioral-change-in-young-adults-with-high-functioning-autism-receiving-virtual-reality-social-cognition-training-a-pilot-study
#17
Y J Daniel Yang, Tandra Allen, Sebiha M Abdullahi, Kevin A Pelphrey, Fred R Volkmar, Sandra B Chapman
Measuring treatment efficacy in individuals with Autism Spectrum Disorder (ASD) relies primarily on behaviors, with limited evidence as to the neural mechanisms underlying these behavioral gains. This pilot study addresses this void by investigating neural and behavioral changes in a Phase I trial in young adults with high-functioning ASD who received an evidence-based behavioral intervention, Virtual Reality-Social Cognition Training over 5 weeks for a total of 10 hr. The participants were tested pre- and post-training with a validated biological/social versus scrambled/nonsocial motion neuroimaging task, previously shown to activate regions within the social brain networks...
May 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29427546/special-interests-and-subjective-wellbeing-in-autistic-adults
#18
Rachel Grove, Rosa A Hoekstra, Marlies Wierda, Sander Begeer
Special interests form part of the core features of autism. However, to date there has been limited research focusing on the role of special interests in the lives of autistic adults. This study surveyed autistic adults on their special interest topics, intensity, and motivation. It also assessed the relationship between special interests and a range of quality of life measures including subjective wellbeing and domain specific life satisfaction. About two thirds of the sample reported having a special interest, with relatively more males reporting a special interest than females...
May 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29427538/the-impact-on-the-family-of-the-co-existing-conditions-of-children-with-autism-spectrum-disorder
#19
Alexandra M Petrou, Abigail Soul, Beena Koshy, Helen McConachie, Jeremy R Parr
We aimed to investigate whether the impact on families of children with Autism Spectrum Disorder (ASD) is associated with the number and/or type of emotional and behavioral co-existing conditions that parents/carers of children with ASD reported as occurring frequently. In addition, we examined whether there was a greater impact on families if their child was male, had lower levels of language, had more severe autism symptomatology, and whether impact was associated with the number and/or type of co-existing conditions...
May 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29424959/influence-of-family-demographic-factors-on-social-communication-questionnaire-scores
#20
Steven A Rosenberg, Eric J Moody, Li-Ching Lee, Carolyn DiGuiseppi, Gayle C Windham, Lisa D Wiggins, Laura A Schieve, Caroline M Ledbetter, Susan E Levy, Lisa Blaskey, Lisa Young, Pilar Bernal, Cordelia R Rosenberg, M Daniele Fallin
This study examined the effect of demographic factors on Social Communication Questionnaire (SCQ) scores in children aged 30-68 months. Diagnoses of ASD were made after a gold standard evaluation that included the Autism Diagnostic Observation Schedule (ADOS), and the Autism Diagnostic Interview Revised (ADI-R). The relationship of demographic variables to SCQ scores was compared in two source populations: (a) children recruited from clinical and educational sources serving children who have ASD or other developmental disorders (CE) and (b) children recruited from birth certificates to represent the general population (BC)...
May 2018: Autism Research: Official Journal of the International Society for Autism Research
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