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Cardiology Journal

Beata Krasińska, Lech Paluszkiewicz, Ewa Miciak-Lawicka, Maciej Krasiński, Piotr Rzymski, Andrzej Tykarski, Zbigniew Krasiński
BACKGROUND: Acetylsalicylic acid (ASA) is one of the basic drugs used in the secondary prevention of coronary heart disease (CAD), and in most cases it is taken in the morning in one daily dose.. It is suggested that the morning peak of platelet aggregation is responsible for the occurrence of myocardial infarctions and strokes. Hence, the aim of the study was to observe the effect of ASA (morning vs. evening) dosing on the anti-aggregative effect of platelets in patients with CAD and arterial hypertension (AH)...
November 28, 2018: Cardiology Journal
Sylwia Wiśniowska-Śmiałek, Ewa Dziewięcka, Katarzyna Holcman, Ewa Wypasek, Lusine Khachatryan, Aleksandra Karabinowska, Maria Szymonowicz, Agata Leśniak-Sobelga, Marta Hlawaty, Magdalena Kostkiewicz, Piotr Podolec, Paweł Rubiś
BACKGROUND: Fibrosis of the extracellular matrix (ECM) in dilated cardiomyopathy (DCM) is common and compromises both systolic and diastolic function. The aim of this study was to investigate the kinetics of ECM fibrosis markers over a 12 month follow-up in patients with DCM based on the severity of diastolic dysfunction (DD). METHODS: Seventy consecutive DCM patients (48 ± 12.1 years, ejection fraction 24.4 ± 7.4%) were included in the study. The grade of DD was determined using the ASE/EACVI algorithm...
November 28, 2018: Cardiology Journal
Simon von Gunten, Dominic A Theuns, Michael Kühne, Tobias Reichlin, Christian Sticherling, Beat Schaer
BACKGROUND: Guidelines of heart failure therapy include cardiac resynchronization as standard of care in patients with severely depressed left ventricular function and wide QRS complex. It has been shown that patients benefit regarding mortality and morbidity. However, early mortality precludes long-term benefits from the device. The aim of the study was to identify predictors for early occurrence of both death and first-ever implantable cardioverter-defibrillator (ICD) therapy using a large combined database of patients with cardiac resynchronization therapy with defibrillator (CRT-D)...
November 28, 2018: Cardiology Journal
Katarzyna Kurnicka, Barbara Lichodziejewska, Michał Ciurzyński, Maciej Kostrubiec, Sylwia Goliszek, Olga Zdończyk, Olga Dzikowska-Diduch, Piotr Palczewski, Marta Skowrońska, Marcin Koć, Katarzyna Grudzka, Piotr Pruszczyk
BACKGROUND: Tricuspid annular plane systolic excursion (TAPSE) is an established index of right ventricular (RV) systolic function and a significant predictor in normotensive patients with pulmonary embolism (PE). Recently, Doppler tissue imaging-derived tricuspid annular systolic velocity (TV S'), a modern parameter of RV function was reported to be useful in the diagnosis and prognosis of a broad spectrum of heart diseases. Therefore, herein, is an analysis of the prognostic value of both parameters in normotensive PE patients...
November 28, 2018: Cardiology Journal
Katarzyna Czerwińska-Jelonkiewicz, Marek Cisowski, Andrzej Bochenek, Piotr Buszman, Krzysztof Milewski, Piotr Kunik, Magdalena Mularska, Krzysztof Kocot, Piotr Politowski, Jakub Brączkowski, Agata Trznadel, Michael S Aboodi, Paweł Buszman
BACKGROUND: Periprocedural antithrombotic prophylaxis in patients undergoing surgical valve procedures (SVP) is insufficiently investigated. Low molecular weight heparin (LMWH) has been considered as an alternative to unfractionated heparin (UFH). However, safety and efficacy of this prophylaxis strategy is unknown. This study aimed to investigate safety and efficacy of periprocedural LMWH prophylaxis and determine optimal dosage and timing for periprocedural cessation and initiation...
November 28, 2018: Cardiology Journal
Tomasz Fabiszak, Piotr Łach, Jakub Ratajczak, Marek Koziński, Wojciech Krupa, Jacek Kubica
BACKGROUND: The aim of the study was to evaluate QRS duration and axis as predictors of response to cardiac resynchronization therapy (CRT) in order to reduce the proportion of non-responders. METHODS: Retrospective single-center study including 42 CRT recipients, with left bundle branch block (LBBB), left ventricular ejection fraction (LVEF) < 40%, in New York Heart Association (NYHA) class ≥ II. Response to CRT was declared as NYHA class improvement ≥ 1 (symptomatic) and LVEF improvement by ≥ 10% (echocardiographic) > 6 months post implantation...
November 16, 2018: Cardiology Journal
Øystein Pettersen, Elżbieta Pociask, Krzysztof P Malinowski, Magdalena Slezak, Knut Hegbom, Rune Wiseth, Dag Ole Nordhaug
BACKGROUND: Optical coherence tomography (OCT) is a high-resolution imaging modality able to provide near-histological images of vessel walls making it possible to distinguish intima and media layers of the vessel wall separately. The use of this imaging technique is increasing while data on the variability and reliability is lacking. The aim of this study was to investigate the reproducibility of frequency-domain OCT in vein grafts used for coronary revascularization. METHODS: Five pullbacks were analyzed by the same analyst with a 1-month delay (intraobserver) and by two different analysts (interobserver)...
November 16, 2018: Cardiology Journal
Klaudiusz Nadolny, Kamil Bujak, Michał Kucap, Przemysław Trzeciak, Bartosz Hudzik, Artur Borowicz, Mariusz Gąsior
BACKGROUND: Despite the introduction of the concept known as "Chain of Survival" has significantly increased survival rates in patients with out-of-hospital cardiac arrest (OHCA), short-term mortality in this group of patients is still very high. Epidemiological data on OHCA in Poland are limited. The aim of this study was to create a prospective registry on OHCA covering a population of 2.7 million inhabitants of Upper Silesia in Poland. Presented herein is the study design and results of a three-month pilot study...
November 16, 2018: Cardiology Journal
Paweł Balsam, Agata Tymińska, Krzysztof Ozierański, Martyna Zaleska, Katarzyna Żukowska, Katarzyna Szepietowska, Kacper Maciejewski, Michał Peller, Marcin Grabowski, Piotr Lodziński, Łukasz Kołtowski, Anna Praska-Ogińska, Inna Zaboyska, Janusz Bednarski, Krzysztof J Filipiak, Grzegorz Opolski
BACKGROUND: The aim of the study was to compare clinical characteristics of real-life AF patients with populations included in randomized clinical trials (ROCKET AF and RE-LY). METHODS: The analysis included 3528 patients who are participants of the ongoing, multicentre, retrospective CRAFT study. The study is registered in NCT02987062. The study is based on a retrospective analysis of hospital records of AF patients treated with vitamin K antagonists (VKAs) (acenocoumarol, warfarin) and non-vitamin K oral anticoagulants (NOACs) (dabigatran, rivaroxaban)...
November 8, 2018: Cardiology Journal
Łukasz Piątek, Krzysztof Wilczek, Jacek Kurzawski, Marek Gierlotka, Mariusz Gąsior, Lech Poloński, Marcin Sadowski
BACKGROUND: Non-ST-segment-elevation myocardial infarction (NSTEMI) has become the most frequently encountered type of MI. The patient clinical profile and management has evolved over the past decade. As there is still a scarcity of data on the latest trends in NSTEMI, changes herein were observed and assessed in the treatment and outcomes in Poland between 2005 and 2014. METHODS: A total of 197,192 patients with NSTEMI who enrolled in the Polish Registry of Acute Coronary Syndromes (PL-ACS) between 2005 and 2014 were analyzed...
November 8, 2018: Cardiology Journal
Piotr Korczyński, Katarzyna Górska, Damian Konopka, Dżamila Al-Haj, Krzysztof J Filipiak, Rafał Krenke
BACKGROUND: Epidemiological data on the causes of pleural effusion (PE) are scarce. Data on the local prevalence of various causes of PE may play a crucial role in the management strategy of patients with PE. The aim of the study was to investigate the causes of PE and to assess 30-day mortality rate in unselected adult patients treated in a large, multidisciplinary hospital. METHODS: Retrospective analysis of medical records, including chest radiographs, of 2835 consecutive patients admitted to the hospital was performed...
November 8, 2018: Cardiology Journal
Dobrin Iotkov Vassilev, Ghassan S Kassab, Carlos Collet, Juan Luis Gutiérrez-Chico, Gianluca Rigatelli, Robert J Gil, Patrick W Serruys
B: ACKGROUND: : The side branch (SB) compromise after main vessel (MV) stenting remains a significant problem in coronary bifurcation treatment. Currently the two major hypotheses for the mechanism of SB compromise are carina shift from MV into the SB and plaque shift into the ostium of side vessel. It is proposed herein, SB ostial deformation leading to reshaping of the ostium from circle to ellipse is a third possible mechanism. In the current study, the theoretical effects and correlation of ostial deformation with fractional flow reserve is explored (FFR)...
November 5, 2018: Cardiology Journal
Guoliang Li, Guy H Fontaine, Shuanliang Fan, Yang Yan, Peter K Bode, Firat Duru, Robert Frank, Ardan M Saguner
BACKGROUND: Atrial fibrillation (AF) is the most common atrial arrhythmia in arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVD). Considering the histologic changes known in the right ventricular (RV) in ARVD, the aim of the present study was to examine right atrial (RA) pathology in patients with ARVD. METHODS: Histology of RA and RV was assessed from autopsy material in 3 patients with ARVD without persistent atrial arrhythmia. RA histology in 3 patients with permanent AF without ARVD and 5 patients without cardiovascular disease was also studied...
November 5, 2018: Cardiology Journal
Adam J Janas, Krzysztof P Milewski, Piotr P Buszman, Wojciech Trendel, Aleksandra Kolarczyk-Haczyk, Mariusz Hochuł, Maciej Pruski, Wojciech Wojakowski, Paweł E Buszman, Radosław S Kiesz
BACKGROUND: The prevalence of diabetes has increased significantly in well-developed countries during the last decade and it continues to grow. Diabetes increases the risk of restenosis in patients treated percutaneously for peripheral artery disease. The present study sought to compare outcomes of atherectomy treatment in diabetic (DM) vs. non-diabetic (nDM) patients suffering from peripheral artery disease. METHOD: Between 2008 and 2012, 204 revascularization atherectomy procedures were performed on arteries of the lower extremities...
November 5, 2018: Cardiology Journal
Jacek Smereka, Łukasz Iskrzycki, Elżbieta Makomaska-Szaroszyk, Karol Bielski, Michael Frass, Oliver Robak, Kurt Ruetzler, Michael Czekajło, Antonio Rodríguez-Núnez, Jesús López-Herce, Łukasz Szarpak
BACKGROUND: The ability to perform high-quality cardiopulmonary resuscitation is one of the basic skills for lifeguards. The aim of the study was to assess the influence of chest compression frequency on the quality of the parameters of chest compressions performed by lifeguards. METHODS: This prospective observational, randomized, crossover simulation study was performed with 40 lifeguards working in Warsaw, Wroclaw, and Poznan, Poland. The subjects then participated in a target study, in which they were asked to perform 2-min cycles of metronome-guided chest compressions at different rates: 80, 90, 100, 110, 120, 130, 140, and 150 compressions per minute (CPM)...
October 19, 2018: Cardiology Journal
Katarzyna Małaczynska-Rajpold, Anna Smukowska-Gorynia, Alice Heaney, Stephen P McKenna, Magdalena Janus, Aleksander Araszkiewicz, Stanislaw Jankiewicz, Sylwia Slawek-Szmyt, Iga Tomaszewska, Tatiana Mularek-Kubzdela
BACKGROUND: Pulmonary hypertension (PH) results in severely impaired quality of life (QoL) in people with this condition. The CAMbridge Pulmonary Hypertension Outcome Review (CAMPHOR) is the only questionnaire providing a disease-specific measurement of symptoms, functioning and QoL in PH patients. It has already been adapted for use in several countries. The aim of this study was to adapt and validate CAMPHOR for the Polish-speaking population. METHODS: Two panels (bilingual and lay) were conducted to translate CAMPHOR into Polish...
October 19, 2018: Cardiology Journal
Serkan Ünlü, Asife Şahinarslan, Burak Sezenöz, Orhan Mecit Uludağ, Gökhan Gökalp, Özden Seçkin, Selim Turgay Arınsoy, Özlem Gülbahar, Nuri Bülent Boyacı
BACKGROUND: Circulating troponin levels are both stable and higher in patients with end-stage renal disease, even in the absence of acute coronary syndrome. These patients commonly have underlying cardiac problems that frequently cause troponin elevation. The effect of hemodialysis (HD) on troponin levels has not been well elucidated. Thus, investigated herein is the relationship between the changes in troponin levels along with left ventricular deformation and volume depletion in patients with end-stage renal disease...
October 19, 2018: Cardiology Journal
Pang Li, Yin Jie, Shi YuGen, Wang Yu, Suhua Yan
BACKGROUND: Inflammation is associated with increased sympathetic drive in cardiovascular diseases (CVDs). The paraventricular nucleus (PVN) of the hypothalamus is a key regulator of sympathetic nerve activity at post-myocardial infarction (MI). High mobility group box-1 (HMGB1) exhibits inflammatory cytokine-like activity in the extracellular space. Inflammation is associated with increased sympathetic drive in CVDs. However, the role of HMGB1 in sympathetic nerve activity at post-MI remains unknown...
October 19, 2018: Cardiology Journal
Izabela Nabiałek-Trojanowska, Ewa Lewicka, Anna Wrona, Anna M Kaleta, Zuzanna Lewicka-Potocka, Grzegorz Raczak, Rafał Dziadziuszko
Over the past decades, effective cancer therapies have resulted in a significant improvement in the survival rates for a number of cancers and an increase in the number of cancer survivors. Radiation therapy is widely used in the treatment of cancer, and it can induce various cardiotoxicities that differ considerably from chemotherapy-induced cardiotoxicity. They occur primarily as late radiation-induced complications, several years from the end of anticancer treatment and present as coronary artery disease, heart failure, pericardial disease, valvular heart disease and arrhythmias...
October 19, 2018: Cardiology Journal
Tomasz Roleder, Magdalena Dobrolinska, Elzbieta Pociask, Wojciech Wanha, Grzegorz Smolka, Wojciech Walkowicz, Radoslaw Parma, Mariusz Lebek, Tomasz Bochenek, Przemysław Pietraszewski, Elvin Kedhi, Andrzej Ochala, Zbigniew Gasior, Ziad A Ali, Wojciech Wojakowski
BACKGROUND: The composition of plaque impacts the results of stenting. The following study evaluated plaque redistribution related to stent implantation using combined near-infrared spectroscopy and intravascular ultrasound (NIRS-IVUS) imaging. METHODS: The present study included 49 patients (mean age 66 ± 11 years, 75% males) presenting with non-ST elevation myocardial infarction (8%), unstable angina (49%) and stable coronary artery disease (43%). The following parameters were analyzed: mean plaque volume (MPV, mm³), plaque burden (PB, %), remodeling index (RI), and maximal lipid core burden index in a 4 mm segment (maxLCBI4mm)...
September 24, 2018: Cardiology Journal
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