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Cardiology Journal

Tomasz Roleder, Magdalena Dobrolinska, Elzbieta Pociask, Wojciech Wanha, Grzegorz Smolka, Wojciech Walkowicz, Radoslaw Parma, Mariusz Lebek, Tomasz Bochenek, Przemysław Pietraszewski, Elvin Kedhi, Andrzej Ochala, Zbigniew Gasior, Ziad A Ali, Wojciech Wojakowski
BACKGROUND: The composition of plaque impacts the results of stenting. The following study evaluated plaque redistribution related to stent implantation using combined near-infrared spectroscopy and intravascular ultrasound (NIRS-IVUS) imaging. METHODS: The present study included 49 patients (mean age 66 ± 11 years, 75% males) presenting with non-ST elevation myocardial infarction (8%), unstable angina (49%) and stable coronary artery disease (43%). The following parameters were analyzed: mean plaque volume (MPV, mm³), plaque burden (PB, %), remodeling index (RI), and maximal lipid core burden index in a 4 mm segment (maxLCBI4mm)...
September 24, 2018: Cardiology Journal
Juan Luis Gutiérrez-Chico, Carlos Cortés, Michele Schincariol, Milosz Jaguszewski
BACKGROUND: Non-occlusive technique is universally accepted for acquisition of coronary optical coherence tomography (OCT), but the amount of contrast infused is still inconsistently calculated. Proposed herein, is an empirical formula for accurate contrast volume calculation. METHODS: In an observational prospective study, contrast volume of consecutive patients undergoing OCT was either calculated with formula, or eyeballed based on manufacturer recommendations...
September 24, 2018: Cardiology Journal
Hui Li, Xiaoyan Li, Jian Guo, Guifu Wu, Chunping Dong, Yaling Pang, Shan Gao, Yangwei Wang
BACKGROUND: The study aimed to uncover the regulation mechanisms of diabetic cardiomyopathy (DCM) and provide novel prognostic biomarkers. METHODS: The dataset GSE62203 downloaded from the Gene Expression Omnibus database was utilized in the present study. After pretreatment using the Affy package, differentially expressed genes (DEGs) were identified by the limma package, followed by functional enrichment analysis and protein-protein interaction (PPI) network analysis...
September 24, 2018: Cardiology Journal
Katharina Schoene, Arash Arya, Cosima Jahnke, Ingo Paetsch, Nikolaos Dagres, Andreas Bollmann, Gerhard Hindricks, Philipp Sommer
BACKGROUND: Thermal injury during radiofrequency ablation (RFA) of atrial fibrillation (AF) can lead to pulmonary vein stenosis (PVS). It is currently unclear if routine screening for PVS by imaging (ECHO, CT) is clinically meaningful and if there is a correlation between PVS and the electroanatomical mapping system (EAMS) used for the ablation procedure. It was therefore investigated in the current single center experience. METHODS: All patients from January 2004 to December 2016 with the diagnosis of PVS after interventional ablation of AF by radiofrequency were retrospectively analyzed...
September 24, 2018: Cardiology Journal
Julia M Umińska, Katarzyna Buszko, Jakub Ratajczak, Piotr Łach, Krzysztof Pstrągowski, Anita Dąbrowska, Piotr Adamski, Grzegorz Skonieczny, Jacek Manitius, Jacek Kubica
BACKGROUND: Mild therapeutic hypothermia (MTH) is a recommended method of treatment for comatose out-of-hospital cardiac arrest (OHCA) survivors. However, the proper site of temperature measurement in MTH is still not defined. The aim of this study was to compare temperature measurements in the esophagus and urinary bladder in comatose post-OHCA patients treated with MTH. METHODS: This temperature comparison protocol was a part of a prospective, observational, multicenter cohort study...
September 24, 2018: Cardiology Journal
Qian Cao, Yundi Jiao, Tongtong Yu, Zhaoqing Sun
BACKGROUND: Thyroid hormones profoundly influence the cardiovascular system, but the effects of mild thyroid dysfunction on the clinical outcome of acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) are not well defined. This study aimed to determine the effect of mild thyroid dysfunction on 12-month prognosis in ACS patients undergoing PCI. METHODS: In this prospective cohort study with a 12-month follow-up, 1560 individuals were divided into four groups based on thyroid hormone levels upon admission: euthyroidism (used as a reference group), subclinical hypothyroidism, subclinical hyperthyroidism, and low triiodothyronine syndrome (low T3 syndrome)...
September 20, 2018: Cardiology Journal
Emmanuel Villa, Margherita Dalla Tomba, Antonio Messina, Andrea Trenta, Federico Brunelli, Marco Cirillo, Zean Mhagna, Giovanni Alfonso Chiariello, Giovanni Troise
BACKGROUND: Aortic valve replacement (AVR) by sutureless prostheses is changing surgeon options, although which patients benefit most, as well as their possible economic impact is still to be defined. METHODS: Perceval-S prosthesis (LivaNova) is reserved, at the documented Institution, for patients at perceived high surgical risk. This retrospective analysis of outcome and resource consumption compared Perceval with other tissue valves. To clarify the comparison, only patients respecting 'instructions-for-use' of Perceval were reviewed...
September 20, 2018: Cardiology Journal
Mark Whitman, Surendran Sabapathy, Carly Jenkins, Lewis Adams
BACKGROUND: Exercise stress testing (EST) in patients with poor functional capacity measured by time on treadmill is typically deemed inconclusive and usually leads to further downstream testing. The aim of this study was firstly to evaluate the maximum rate pressure product (MRPP) during initial EST to assessthe need for follow-up testing; and secondly to investigate if MRPP is better than age predicted maximum heart rate (APMHR) for diagnostic outcome based on follow up cardiovascular (CV) events in patients with inconclusive EST due to poor functional capacity...
September 20, 2018: Cardiology Journal
Agnieszka Mickiewicz, Justyna Borowiec-Wolna, Witold Bachorski, Natasza Gilis-Malinowska, Rafał Gałąska, Grzegorz Raczak, Magdalena Chmara, Bartosz Wasąg, Miłosz J Jaguszewski, Marcin Fijałkowski, Marcin Gruchała
BACKGROUND: Severe familial hypercholesterolemia (FH) individuals, refractory to conventional lipid-lowering medications are at exceptionally high risk of cardiovascular events. The established therapeutic option of last choice is lipoprotein apheresis (LA). Herein, it was sought to investigate the clinical usefulness of LA in a highly selected group of severe heterozygous FH (HeFH), as recently described by the International Atherosclerosis Society (IAS), for their efficacy in lipid reduction and safety...
September 20, 2018: Cardiology Journal
Mateusz K Hołda, Paweł Iwaszczuk, Karolina Wszołek, Jakub Chmiel, Andrzej Brzychczy, Mariusz Trystuła, Marcin Misztal
BACKGROUND: Abdominal aortic aneurysm (AAA) and coronary atherosclerosis share common risk factors. In this study, a single-center management experience of patients with a coexistence of AAA and coronary artery disease (CAD) is presented. METHODS: 271 consecutive patients who underwent elective AAA repair were reviewed. Coronary imaging in 118 patients was considered suitable for exploration of AAA coexistence with CAD. RESULTS: Significant coronary stenosis (> 70%) were found in 65...
September 20, 2018: Cardiology Journal
Rafał A Januszek, Artur Dziewierz, Zbigniew Siudak, Tomasz Rakowski, Jacek Legutko, Łukasz Rzeszutko, Paweł Kleczyński, Dariusz Dudek, Stanisław Bartuś
BACKGROUND: This study is to assess differences in periprocedural outcomes among diabetic and non-diabetic patients treated with percutaneous coronary intervention (PCI) and rotational atherectomy (RA). METHODS: Under assessment were 221,187 patients from the Polish Cardiovascular Intervention Society national registry (ORPKI) including all PCIs performed in Poland in 2015 and 2016. Data was extracted of 975 patients treated with RA - 336 (34.5%) diabetics and 639 (65...
September 20, 2018: Cardiology Journal
Ryszard Targoński, Janusz Sadowski, Magdalena Starek-Stelmaszczyk, Radosław Targoński, Andrzej Rynkiewicz
BACKGROUND: Red cell distribution width (RDW) in acute heart failure (AHF) is accepted as a prognostic indicator with unclear pathophysiological ties. The aim of this study was to evaluate the prognostic value of RDW in AHF patients in relation to clinical and echocardiographic data. METHODS: 170 patients with AHF were retrospectively studied. All patients had laboratory testing and an echocardiogram performed within 24 h of admission to the Cardiology Department...
September 20, 2018: Cardiology Journal
Amr Salama, Abdullah Abdullah, Abdul Wahab, George Eigbire, Ryan Hoefen, Richard Alweis
BACKGROUND: Sarcoidosis is an increasingly recognized multi-systemic condition. Cardiac sarcoidosis is associated with ventricular arrhythmias and higher mortality rates. Little epidemiological data is available regarding the disease and associated ventricular arrhythmias. METHODS: Data from the National Inpatient Sample (NIS) database 2012-2014, were reviewed. Discharges associated with sarcoidosis were identified as the target population using relevant ICD-9-CM codes...
September 20, 2018: Cardiology Journal
Yunxiao Chang, Liwei Chen, Jelmer Westra, Zhongwei Sun, Changdong Guan, Yimin Zhang, Daixin Ding, Bo Xu, Shengxian Tu
BACKGROUND: Quantitative flow ratio (QFR) is a novel approach to derive fractional flow reserve (FFR) from coronary angiography. This study sought to evaluate the reproducibility of QFR when analyzed in independent core laboratories. METHODS: All interrogated vessels in the FAVOR II China Study were separately analyzed using the AngioPlus system (Pulse medical imaging technology, Shanghai) by two independent core laboratories, following the same standard operation procedures...
September 20, 2018: Cardiology Journal
Ayman Jubran, Anna Zetser, Barak Zafrir
BACKGROUND: Elevated lipoprotein(a) [Lp(a)] is an independent risk factor for coronary artery disease (CAD). However, its role in real-world practice and implications for clinical care remains limited. Under investigation herein, are the clinical characteristics associated with increased Lp(a) levels in patients presenting with acute coronary syndrome (ACS). METHODS: Lp(a) was measured at admission in patients ≤ 65 years of age presenting with ACS in a single center...
September 20, 2018: Cardiology Journal
Paweł Kleczyński, Paweł Petkow Dimitrow, Artur Dziewierz, Agata Wiktorowicz, Tomasz Rakowski, Andrzej Surdacki, Dariusz Dudek
BACKGROUND: There is a paucity of data regarding response of cerebral blood flow to the postural unloading maneuver and its impact on the risk of syncope in patients with aortic stenosis (AS). The aim of the present study was to assess effects of orthostatic stress test on changes in carotid and vertebral artery blood flow and its association with syncope in patients with severe AS. METHODS: 108 patients were enrolled (72 with and 36 patients without syncope) with severe isolated severe AS...
September 20, 2018: Cardiology Journal
Piotr Duchnowski, Tomasz Hryniewiecki, Mariusz Kuśmierczyk, Piotr Szymański
BACKGROUND: The aim of the study was to investigate the prognostic value of selected biomarkers in patients with aortic regurgitation undergoing valve surgery. M: ETHODS: A prospective study was conducted on a group of consecutive patients with hemodynamically significant aortic regurgitation that underwent elective aortic valve surgery. The primary endpoint was 30-day mortality and any major adverse event within 30 days. RESULTS: The study group included 205 consecutive patients who underwent replacement or repair of the aortic valve...
September 20, 2018: Cardiology Journal
Monika Sznajder, Olga Dzikowska-Diduch, Katarzyna Kurnicka, Marek Roik, Dominik Wretowski, Piotr Pruszczyk, Maciej Kostrubiec
BACKGROUND: Chronic thromboembolic pulmonary hypertension (CTEPH) is a complication of venous thromboembolism (VTE) resulting from non-dissolving thromboembolic in the pulmonary arteries. Previous observations indicate a higher prevalence of atherosclerosis and cardiovascular risk factors in patients with VTE and CTEPH. The purpose of the present study was to evaluate the arterial stiffening assessed by pulse wave velocity (PWV), a marker of arterial stiffness, in CTEPH patients in comparison with a matched control group (CG)...
September 20, 2018: Cardiology Journal
Pawel Burchardt, Maura Farinacci, Magdalena Mayer, Klaus Luecke, Thomas Krahn, Jaroslaw Manczak, Marek Slomczynski, Jaroslaw Hiczkiewicz, Janusz Rzezniczak
BACKGROUND: Circulating endothelial cells (CEC) may be used to find new strategies for the early diagnosis of cardiovascular diseases. The major objective of the project is to broaden knowledge of CEC biology by determining their phenotypic characteristics. The additional aim is to clarify whether on the basis of these information it is possible to identify the origin of CEC release (from various cardiovascular compartments). METHODS: Circulating endothelial cells were collected from arterial blood prior to angiography, as well as from arterial and venous blood obtained after angiography/coronary angioplasty, from 18 patients with non-ST-segment elevation myocardial infarction (NSTEMI)...
September 20, 2018: Cardiology Journal
Marcin Grabowski, Marcin Michalak, Monika Gawałko, Sylwia Gajda, Andrzej Cacko, Łukasz Januszkiewicz, Agnieszka Kołodzińska, Przmysław P Mitkowski, Gabor Z Duray, Grzegorz Opolski
BACKGROUND: The Micra Transcatheter Pacing System (TPS) is a miniaturized, single-chamber pacemaker system. Reported herein is an initial experience with implantation of the Micra TPS. METHODS: The leadless pacemaker was implanted in 10 patients with standard indications for a permanent pacemaker. All hospitalization costs were calculated for all patients. RESULTS: The mean age of the patients was 75 ± 7.1 years, 6 were men and 4 were women...
August 29, 2018: Cardiology Journal
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