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Cardiology Journal

Kevin Mohee, Omar Aldalati, Rafal Dworakowski, Hasan Haboubi
Angiodyplasia and aortic stenosis are both conditions that are highly prevalent in elderly people and can often co-exist. Recent studies suggest that this association is related to subtle alterations in plasma coagulation factors. The Von Willebrand factor is the strongest link between aortic stenosis and bleeding associated with gastrointestinal angiodysplasia. With an ageing population, the disease burden of aortic stenosis and its association with angiodysplasia of the bowel makes this an incredibly underdiagnosed yet important condition...
July 16, 2018: Cardiology Journal
Chan Joon Kim, Eun Ji Han, Eun-Ho Chu, Byung-Hee Hwang, Jin-Jin Kim, Ki-Bae Seung, Sung Hoon Kim, Joon Hyun O, Kiyuk Chang
BACKGROUND: Asian patients with acute coronary syndrome (ACS) are frequently prescribed moderate-intensity statin in real practice, even during the early stage of ACS. Under assessment herein was the effect of moderate-intensity statin therapy on the resolution of plaque inflammation during the first month after ACS, a period with highest recurrent ischemic events, using dual time point ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT). METHODS: This prospective study included statin-naïve patients with ACS and non-calcified carotid plaques (³ 3 mm on ultrasound images)...
July 16, 2018: Cardiology Journal
Guo-Liang Li, Ardan M Saguner, Guy H Fontaine, Robert Frank
BACKGROUND: Bradycardia-induced torsade de pointes (TdP) tachycardia in patients with spontaneous high-degree atrioventricular block (AVB) is common. The aim of this study was to analyze endocardial recordings during TdP in spontaneous high-degree AVB in humans to better understand the electrophysiological mechanisms underlying this phenomenon. METHODS: The study group consisted of 5 patients with typical episodes of TdP during spontaneous high-degree AVB. A standard (USCI) temporary bipolar endocardial catheter positioned at the apex of the right ventricle (RV) and bipolar chest leads from two precordial leads V1 and V4 were used to record the tracings during TdP...
July 16, 2018: Cardiology Journal
Ping Jiang, Ying Song, Jing-Jing Xu, Huan-Huan Wang, Lin Jiang, Wei Zhao, Xue-Yan Zhao, Jue Chen, Zhan Gao, Shu-Bin Qiao, Yue-Jin Yang, Run-Lin Gao, Bo Xu, Jin-Qing Yuan
BACKGROUND: Mean platelet volume (MPV) is a marker of platelet size and activity, and is associated with a poor prognosis of cardiovascular disease. Studies have shown a relationship between diabetes mellitus (DM) and MPV. This study examined the relationship between admission MPV and 2-year cardiac mortality in patients with DM and stable coronary artery disease (SCAD) undergoing elective percutaneous coronary intervention (PCI). METHODS: A total of 1389 patients were enrolled and divided into two groups according to MPV as follows: lower MPV (n = 908, MPV ≤ 10...
July 16, 2018: Cardiology Journal
Jun-Hyok Oh, Seunghwan Song, Changhoon Kim, Jinhee Ahn, Jin Sup Park, Hye Won Lee, Jung Hyun Choi, Han Cheol Lee, Kwang Soo Cha, Taek Jong Hong
BACKGROUND: This study aimed to evaluate the effect of adenosine on epicardial coronary artery diameter during ergonovine provocation testing. METHODS: A total of 158 patients who underwent an ergonovine provocation test with intracoronary adenosine injection between 2011 and 2014 were selected. Patients were divided into four groups based on the severity of percent diameter stenosis following intracoronary ergonovine administration: Group 1, induced spasm < 50%; Group 2, 50-89%; Group 3, 90-99%; and Group 4, total occlusion...
July 16, 2018: Cardiology Journal
Cristina Jorge-Soto, Maite Abilleira-González, Martin Otero-Agra, Roberto Barcala-Furelos, Cristian Abelairas-Gómez, Lukasz Szarpak, Antonio Rodríguez-Núñez
BACKGROUND: The aim was to assess future schoolteachers' basic life support (BLS) knowledge and willingness to include this content in school lessons. The aim was also to determine the learning effect of a brief BLS hands-on training session, supported by real-time feedback. METHODS: A convenience sample of 98 University students of Educational Sciences and Sports were recruited. The training program consisted of brief theoretical and hands-on interactive sessions with a 2/10 instructor/participants ratio...
July 16, 2018: Cardiology Journal
Gaigai Ma, Quan Fang, Fengxia Wang
BACKGROUND: Beta-blockers (BB) are the cornerstone of therapy for heart failure (HF); however, the effects of these drugs on the prognosis of patients with concomitant atrial fibrillation (AF) remain controversial. The objective of this meta-analysis was to evaluate the efficacy of BB on mortality in HF coexisting with AF. METHODS: A systematic search of PubMed, EMBASE and the Cochrane Library databases was conducted. Observational cohort studies (OCSs) and randomized controlled studies (RCTs) reporting outcomes of mortality or HF hospitalizations for patients with HF and AF, being assigned to BB treatment and non-BB group were included...
July 16, 2018: Cardiology Journal
Christian-Hendrik Heeger, Christopher Schuette, Valentina Seitelberger, Erik Wissner, Andreas Rillig, Shibu Mathew, Bruno Reissmann, Christine Lemes, Tilman Maurer, Thomas Fink, Osamu Inaba, Naotaka Hashiguchi, Francesco Santoro, Feifan Ouyang, Karl-Heinz Kuck, Andreas Metzner
BACKGROUND: The second-generation cryoballoon (CB2) provides effective and durable pulmonary vein isolation (PVI) associated with encouraging and reproducible clinical outcome data. The latest-generation cryoballoon (CB3) incorporates a 40% shorter distal tip, thus allowing for an increased rate of PVI real-time signal recording and facilitating individualized ablation strategies taking the time-to-effect (TTE) into account. However, whether this characteristic translates into favorable clinical success has not been evaluated yet...
June 20, 2018: Cardiology Journal
Łukasz Zandecki, Marcin Sadowski, Marianna Janion, Jacek Kurzawski, Marek Gierlotka, Lech Poloński, Mariusz Gąsior
BACKGROUND: Nowadays, the majority of patients with myocardial infarction with ST-segment elevation (STEMI) are treated with primary percutaneous coronary interventions (pPCI). In recent years, there have been ongoing improvements in PCI techniques, devices and concomitant pharmacotherapy. However, reports on further mortality reduction among PCI-treated STEMI patients remain inconclusive. The aim of this study was to compare changes in management and mortality in PCI-treated STEMI patients between 2005 and 2011 in a real-life setting...
June 20, 2018: Cardiology Journal
Jan-Erik Guelker, Alexander Bufe, Christian Blockhaus, Knut Kroeger, Thomas Rock, Ibrahim Akin, Michael Behnes, Kambis Mashayekhi
BACKGROUND: The plasma-derived atherogenic index (AIP) is associated with an increasing risk for cardiovascular diseases. Whether an increased AIP may predict the complexity of percutaneous coronary intervention (PCI) of chronic total occlusion (CTO), according to available research, has never been investigated before. METHODS: 317 patients were included prospectively and treated with PCI for at least one CTO between 2012 and 2017. High-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) plasma levels were measured 24 h before PCI...
June 20, 2018: Cardiology Journal
Hiroki Shibutani, Yuzo Akita, Yohei Oishi, Hiroyuki Sueyoshi, Yu Mukai, Kotaro Yutaka, Yumie Matsui, Masahiro Yoshinaga, Masahiro Karakawa
Background: A new complication, longitudinal stent deformation (LSD), is increasingly reported with recent intracoronary stent designs. There have been experiences of unusual cases of distal LSD caused by entrapment of a Lacrosse® non-slip element (NSE) balloon (Goodman Co., Ltd., Nagoya, Japan), which has three flexible nylon elements to prevent slippage. Accordingly, the aim of this study is to report the clinical experience of distal LSD caused by the NSE in the documented center and to investigate the incidence and mechanisms involved...
June 20, 2018: Cardiology Journal
Vanesa Cristina Lozano Granero, Sara Fernández Santos, Covadonga Fernández-Golfín, María Plaza Martín, Jesús María de la Hera Galarza, Francesco Fulvio Faletra, Martin J Swaans, Teresa López-Fernández, Dolores Mesa, Giovanni La Canna, Tomás Echeverría García, Gilbert Habib, Amparo Martíne Monzonís, José Luis Zamorano Gómez
BACKGROUND: Left ventricular (LV) mechanics are impaired in patients with severe aortic stenosis (AS). Transcatheter aortic valve replacement (TAVR) has become a widespread technique for patients with severe AS considered inoperable or high risk for traditional open-surgery. This procedure could have a positive impact in LV mechanics. The aim of this study was to evaluate the immediate effect of TAVR on LV function recovery, as assessed by myocardial deformation parameters. METHODS: One-hundred twelve consecutive patients (81...
June 20, 2018: Cardiology Journal
Aleksandra Liżewska-Springer, Alicja Dąbrowska-Kugacka, Ewa Lewicka, Łukasz Drelich, Tomasz Królak, Grzegorz Raczak
BACKGROUND: Catheter ablation (CA) is a well-known treatment option for patients with symptomatic drug-resistant atrial fibrillation (AF). Multiple factors have been identified to determine AF recurrence after CA, however their predictive value is rather small. Identification of novel predictors of CA outcome is therefore of primary importance to reduce health costs and improve long-term results of this intervention. The recurrence of AF following CA is related to the severity of left ventricular (LV) dysfunction, extend of atrial dilatation and fibrosis...
June 20, 2018: Cardiology Journal
Juan Luis Gutiérrez-Chico, Carlos Cortés, Michele Schincariol, Ula Limon, Meric Yalcinli, María-Alexandra Durán-Cortés, Milosz Jaguszewski
BACKGROUND: We hypothesise that a comprehensive optical coherence tomography (OCT)-guided implantation protocol for bioresorbable scaffolds (BRS) might improve expansion and apposition, thus translating into better clinical outcomes, particularly reducing thrombotic events. METHODS: Patients considered suitable for BRS therapy in de novo coronary lesions underwent OCT. The predominant type of plaque was classified as lipidic, fibrous or calcific, undergoing tailored plaque preparation accordingly...
May 18, 2018: Cardiology Journal
Koldobika Villelabeitia-Jaureguizar, Davinia Vicente-Campos, Alejandro Berenguel Senen, Verónica Verónica Hernández Jiménez, Lorena Lorena Ruiz Bautista, María Elvira Barrios Garrido-Lestache, Jose López Chicharro
BACKGROUND: Mechanical efficiency (ME) refers to the ability of an individual to transfer energy consumed by external work. A decreased ME, could represent an increased energy cost during exercise and may, therefore, be limited in terms of physical activity. This study aimed to compare the influence of two different exercise protocols: moderate continuous training (MCT) versus high intensity interval training (HIIT), as part of a cardiac rehabilitation program on ME values among coronary patients...
May 10, 2018: Cardiology Journal
Yongcheol Kim, Sung Sik Oh, Myung Ho Jeong, Youngkeun Ahn, Ju Han Kim, Young Joon Hong, Doo Sun Sim, Min Chul Kim, Hyo-Soo Kim, Kyeong Ho Yun, Seok Kyu Oh, Chong Jin Kim, Myeong Chan Cho
BACKGROUND: There are few studies which compare the efficacy and safety of the Resolute Onyx zotarolimus-eluting stent (O-ZES) and everolimus-eluting stent (EES) in patients with acute myocardial infarction (AMI). Therefore, the present study aimed to compare clinical outcomes of O-ZES and EES in patients with AMI undergoing successful percutaneous coronary intervention (PCI). METHODS: From January 2016 to December 2016, the Korea Acute Myocardial Infarction Registry (KAMIR) enrolled 3,364 consecutive patients...
May 10, 2018: Cardiology Journal
Jingwen Xia, Nianxin Jiang, Yansong Li, Yong Wei, Xuan Zhang
BACKGROUND: Myocardial infarction (MI) is a leading cause of disease with high morbidity and mortality worldwide. Recent studies have revealed that long non-coding RNAs (lncRNAs) are involved in heart disease pathogenesis. This study aimed to investigate the effect and the molecular basis of THRIL on hypoxia-injured H9C2 cells. METHODS: THRIL, miR-99a and Brahma-related gene 1 (Brg1) expression in H9C2 cells were altered by transient transfections. The cells were subjected to hypoxia for 4 h, and then the levels of THRIL, miR-99a and Brg1 were investigated...
May 10, 2018: Cardiology Journal
Chieh-Yu Liu, Hui-Chun Chen
BACKGROUND: This study aimed to investigate the effectiveness of monotherapy aspirin and warfarin for stroke prevention in low-risk atrial fibrillation (AF) by using a population-based cohort study in Taiwan. METHODS: A newly diagnosed low-risk AF patient cohort were identified by using National Health Insurance Research Database (NHIRD) in Taiwan in 2008. The study cohort was observed with a follow-up of 2 years to examine the onset of ischemic stroke (IS) (to 2010)...
May 2, 2018: Cardiology Journal
Cesar Khazen, Peter Magnusson, Johannes Flandorfer, Christoph Schukro
BACKGROUND: The aim of the study was to evaluate subcutaneous implantable cardioverter-defibrillator (S-ICD) patients with regard to underlying etiology, peri-procedural outcome, appropriate/inappropriate shocks, and complications during follow-up. METHODS: All patients who underwent S-ICD implantation from February 2013 to March 2017 at an academic hospital in Vienna were included. Medical records were examined and follow-up interrogations of devices were conducted...
May 2, 2018: Cardiology Journal
Xuhui Ma, Pengfei Hu, Haifeng Chen, Tianfu Fang
BACKGROUND: Recent studies have identified amphoterin-induced gene and open reading frame (AMIGO) 2. The role of AMIGO2 in tumour research is well-studied, but its role in ischemic heart diseases is seldom reported. In the present study, the role of AMIGO2 in myocardial infarction is under investigation for the first time. METHODS: For in vitro studies, cardiomyocytes (CMs) and endothelial cells (ECs) were isolated from both AMIGO2 knockout (KO) and WT mice. The apoptosis of CMs was tested after 48 h of ischemic stimulation...
May 2, 2018: Cardiology Journal
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