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Cardiology Journal

Marcin Grabowski, Monika Gawałko, Marcin Michalak, Andrzej Cacko, Michał Kowara, Agnieszka Kołodzińska, Łukasz Januszkiewicz, Paweł Balsam, Laura Vitali Serdoz, Joachim Winter, Grzegorz Opolski
BACKGROUND: The recent introduction of an entirely subcutaneous implantable cardioverter-defibrillator (S-ICD) represents an important progress in the defibrillation technology towards a less invasive approach. This is a single-center observational study of S-ICD implantations in Poland. METHODS: The S-ICD was implanted in 11 patients with standard indications for an ICD. Patients in whom the device was implanted were evaluated for adverse events and device function at hospital discharge...
April 3, 2018: Cardiology Journal
Stanislaw Szczerbinski, Jakub Ratajczak, Piotr Lach, Jakub Rzeszuto, Przemyslaw Paciorek, Joanna Karlowska-Pik, Bartosz Ziemkiewicz, Malgorzata Jasiewicz, Aldona Kubica
BACKGROUND: Although recent studies indicate temporal variations in the incidence of out-of-hospital cardiac arrest (OHCA), the Polish experience in this research is scarce to date. Epidemiology of OHCA and circadian is evaluated herein, weekly and seasonal variations of OHCA frequency among the adult population of the Opole district, Poland. METHODS: The retrospective analysis of 815 OHCA cases with presumed cardiac etiology was made based on dispatch cards from the Emergency Medical Center in Opole registered during a 2 year period (2006-2007)...
April 3, 2018: Cardiology Journal
Paweł S Kaczmarczyk, Paweł Maga, Rafał Niżankowski, Rafał Januszek, Marzena Frołow, Mikołaj Maga, Jolanta Kościelniak, Andrzej Belowski
BACKGROUND: The aim of the current study was to assess the relationship between potential predictors of clinical outcomes after percutaneous transluminal angioplasty (PTA) of peripheral arteries during a one-year follow-up. Indices of endothelial function (EF), arterial pulse waveform analysis (aPWA) and markers of peripheral arteries ischemia were among those mostly examined. METHODS: The study comprised of 72 individuals with PAD who underwent PTA of the peripheral arteries...
April 3, 2018: Cardiology Journal
You-Hua Huang, Qiang Xu, Tao Shen, Jian-Ke Li, Jing-Yu Sheng, Hong-Jian Shi
BACKGROUND: Even with drug-eluting stents, the risk of in-stent restenosis (ISR) remains high. The goal of this study was to investigate the use of an endothelial progenitor cell (EPC) capture stent plus regional EPC transplantation to reduce the ISR rate. METHODS: Endothelial progenitor cell capture stents were fabricated using fibrin gel and anti-CD34 plus anti-VEGFR-2 dual antibodies. Twenty male New Zealand white rabbits established as an atherosclerotic model were randomly divided into two groups: group 1 (n = 10), in which EPC capture stents were deployed into the right iliac artery; and group 2 (n = 10), in which sirolimus-eluting stents were placed...
April 3, 2018: Cardiology Journal
Jun-Qing Gao, Wei Yang, Zong-Jun Liu
B: ACKGROUND: Renal denervation (RDN) is as an effective treatment for heart failure, but its effects on cardiac function of patients with heart failure (HF) are not well documented. Here, the aim was to investigate RDN's effect on patients with chronic systolic HF, by conducting a single-center, prospective, randomized, and controlled study. M: ETHODS: Sixty patients with chronic systolic HF were randomly assigned to the RDN or control groups, receiving percutaneous catheter-based RDN with radiofrequency ablation and drug treatment respectively...
April 3, 2018: Cardiology Journal
Laurent M Haegeli, Linda Stutz, Mohammed Mohsen, Thomas Wolber, Corinna Brunckhorst, Chol-Jun On, Firat Duru
BACKGROUND: Awareness of risks associated with radiation exposure to patients and medical staff has significantly increased. It has been reported before that the use of advanced three-dimensional electro-anatomical mapping (EAM) system significantly reduces fluoroscopy time, however this study aimed for zero or near zero fluoroscopy ablation to assess its feasibility and safety in ablation of atrial fibrillation (AF) and other tachyarrhythmias in a "real world" experience of a single tertiary care center...
April 3, 2018: Cardiology Journal
Rahel Befekadu, Kjeld Christiansen, Anders Larsson, Magnus Grenegård
BACKGROUND: The role of cathepsins in the pathological progression of atherosclerotic lesions in ischemic heart disease have been defined in detail more than numerous times. This investigation examined the platelet-specific biomarker trombospondin-1 (TSP-1) and platelet function ex vivo, and compared this with cathepsin S (Cat-S; a biomarker unrelated to platelet activation but also associated this with increased mortality risk) in patients with ST segment elevation myocardial infarction (STEMI)...
April 3, 2018: Cardiology Journal
Fei Chen, Jia-Qi Li, Yuan-Wei-Xiang Ou, Tian-Li Xia, Fang-Yang Huang, Hua Chai, Bao-Tao Huang, Qiao Li, Xiao-Bo Pu, Guo-Yong Li, Yong Peng, Mao Chen, De-Jia Huang
BACKGROUND: The impact of renal function on the prognostic value of N-terminal B-type natriuretic peptide (NT-proBNP) remains unclear in coronary artery disease (CAD). This study sought to investigate the value of using NT-proBNP level to predict prognoses of CAD patients with different estimated glomerular filtration rates (eGFRs). METHODS: A retrospective analysis was conducted from a single registered database. 2087 consecutive patients with CAD confirmed by coronary angiography were enrolled...
April 3, 2018: Cardiology Journal
Xiao-Fei Xie, Hong-Juan Chu, Yu-Fen Xu, Liang Hua, Zhou-Ping Wang, Ping Huang, Hong-Ling Jia, Li Zhang
BACKGROUND: To study the protein profile of the serum exosomes of patients with coronary artery aneurysms (CAA) caused by Kawasaki disease (KD). METHODS: Two-dimensional electrophoresis (2-DE) was used to identify proteins from the exosomes of serum obtained from children with CAA caused by KD, as well as healthy controls. Differentially expressed proteins were identified using matrix-assisted laser desorption/ionization time-of-flight/time-of-flight mass spectrometry (MALDI-TOF/TOF MS) analysis...
April 3, 2018: Cardiology Journal
Janosch Cupa, Ivo Strebel, Patrick Badertscher, Roger Abächerli, Raphael Twerenbold, Lukas Schumacher, Jasper Boeddinghaus, Thomas Nestelberger, Patrick Maechler, Nikola Kozhuharov, Maria Rubini Giménez, Karin Wildi, Jeanne du Fay de Lavallaz, Zaid Sabti, Lorraine Sazgary, Christian Puelacher, Deborah Mueller, Chiara Bianci, Òscar Miró, Carolina Fuenzalida, Sofia Calderón, Javier Martin-Sanchez, Sergio Lopez Iglesias, Beata Morawiec, Damian Kawecki, Jiri Parenica, Dagmar I Keller, Nicolas Geigy, Stefan Osswald, Christian Mueller, Tobias Reichlin
BACKGROUND: While prolongation of QRS duration and QTc interval during acute myocardial infarction (AMI) has been reported in animals, limited data is available for these readily available electrocardiography (ECG) markers in humans. METHODS: Diagnostic and prognostic value of QRS duration and QTc interval in patients with suspected AMI in a prospective diagnostic multicentre study were prospectively assessed. Digital 12-lead ECGs were recorded at presentation. QRS duration and QTc interval were automatically calculated in a blinded fashion...
April 3, 2018: Cardiology Journal
Hai-Tao Yang, Wen-Juan Xiu, Ying-Ying Zheng, Fen Liu, Ying Gao, Xiang Ma, Yi-Ning Yang, Xiao-Mei Li, Yi-Tong Ma, Xiang Xie
BACKGROUND: Early myocardial reperfusion therapy ( < 12 h) in patients with acute myocardial infarction (AMI) can significantly improve their prognosis. However, the effect of late reperfusion ( > 12 h) remains controversial. In this study, the effects of late reperfusion versus standard drug therapy on the outcomes of patients with AMI were evaluated by systematic review and meta-analysis. METHODS: PubMed, Embase, Medline, Cochrane, Wanfang, and CNKI databases were searched for eligible studies for the present study...
April 3, 2018: Cardiology Journal
Michael Sacherer, Ewald Kolesnik, Friederike von Lewinski, Nicolas Verheyen, Karin Brandner, Markus Wallner, Deborah M Eaton, Olev Luha, Robert Zweiker, Dirk von Lewinski
BACKGROUND: Devices currently used to achieve hemostasis of the femoral artery following percutaneous cardiac catheterization are associated with vascular complications and remnants of artificial materials are retained at the puncture site. The SECURE arterial closure device induces hemostasis by utilizing thermal energy, which causes collagen shrinking and swelling. In comparison to established devices, it has the advantage of leaving no foreign material in the body following closing...
April 3, 2018: Cardiology Journal
Pawel Nadrowski, Ewa Podolecka, Andrzej Pajak, Agnieszka Dorynska, Wojciech Drygas, Wojciech Bielecki, Magdalena Kwasniewska, Andrzej Tykarski, Arkadiusz Niklas, Tomasz Zdrojewski, Michal Skrzypek, Wojciech Wojakowski, Krystyna Kozakiewicz
BACKGROUND: Socioeconomic status (SES) is an important factor of cardiovascular diseases (CVD) development. A decline in death from CVD among subjects with high SES is observed in developed countries. The aim of this study was to assess differences in cardiovascular risk between socioeconomic classes in Poland, a country currently in transition. METHODS: A sample of 15200 people was drawn. A three stage selection was performed. Eventually, 6170 patients were examined (2013/2014)...
March 23, 2018: Cardiology Journal
Marius Schwerg, Karl Stangl, Michael Laule, Verena Stangl, Henryk Dreger
BACKGROUND: The new CoreValve Evolut R has an improved design to minimize paravalvular leakage (PVL) and allows repositioning of the valve. For patients with degenerated bioprosthetic aortic valves, transcatheter aortic valve implantation (TAVI) represents a less invasive option. Herein reported are valve-in-valve (ViV) implantations of this new valve. METHODS: A total of 26 patients (mean age 79.4 ± 6.1 years, 17 males and 9 females) were treated for severe prosthesis stenosis (n = 9), severe regurgitation (n = 8) or severe combination of stenosis and regurgitation (n = 9)...
March 23, 2018: Cardiology Journal
Satoru Kayama, Shungo Aratake, Shegehito Sawamura, Yusuke Watanabe, Ken Kozuma
BACKGROUND: The effects of left ventricular (LV) diastolic function are well known in cardiac surgery, but unclear in transcatheter aortic valve implantation (TAVI). The objective of this study was to examine the association of preoperative LV diastolic function with medium to long-term outcomes of TAVI. METHODS: Eighty patients who underwent TAVI were classified into grades I, II and III based on preoperative LV diastolic function. Findings related to cardiovascular outcomes after TAVI were extracted retrospectively from clinical and echocardiographic data and relationships with diastolic function were examined...
March 23, 2018: Cardiology Journal
Baotong Li, Hengchao Wu, Hansong Sun, Jianping Xu, Yunhu Song, Wei Wang, Shuiyun Wang
BACKGROUND: Although practice guidelines recommend surgery for patients with severe chronic ischemic mitral regurgitation (CIMR), they do not specify whether to repair or replace the mitral valve. The purpose of this study was to evaluate the long-term outcomes in patients with severe CIMR undergoing mitral valve annuloplasty (MVA) versus subvalvular sparing mitral valve replacement (MVR). METHODS: 392 consecutive patients who underwent MVA or subvalvular sparing MVR for treatment of severe CIMR were retrospectively reviewed...
March 23, 2018: Cardiology Journal
Jürgen Duchenne, Piet Claus, Efstathios D Pagourelias, Razvan O Mada, Joeri Van Puyvelde, Kathleen Vunckx, Eric Verbeken, Olivier Gheysens, Filip Rega, Jens-Uwe Voigt
BACKGROUND: A-V-sequential pacing has been shown to induce reversible conduction delay and subsequent asymmetric remodelling of the left ventricle (LV) in dogs and pigs. Both species have disadvantages in animal experiments. Therefore aim of this study focusses at developing a more feasible and easy-to-use animal model in sheep. METHODS: Dual-chamber pacing (DDD) pacemakers (right atrium + right ventricular free wall) were surgically implanted in 13 sheep. All animals underwent 8 weeks of chronic rapid pacing at 180 bpm...
March 23, 2018: Cardiology Journal
Jia Ling, Zhenrong Cai, Wei Jin, Xiaohua Zhuang, Lihong Kan, Fei Wang, Xiaolei Ye
BACKGROUND: The shRNA lentiviral vector was constructed to silence c-Ski expression in cardiac muscle cells, with the aim of exploring the role of c-Ski in transforming growth factor β1 (TGF-β1)-induced epithelial-mesenchymal transitions (EMT) in H9C2 cells. METHODS: RT-PCR and western blot were used to detect c-Ski expression at protein and messenger ribonucleic acid (mRNA) levels in 5 different cell lines. Then, lentiviral vector was constructed to silence or overexpress c-Ski in H9C2 cells...
March 23, 2018: Cardiology Journal
Babikir Kheiri, Ahmed Abdalla, Mohammed Osman, Sahar Ahmed, Mustafa Hassan, Ghassan Bachuwa
BACKGROUND: Cryptogenic strokes can be attributed to paradoxical emboli through patent foramen ovale (PFO). However, the effectiveness of PFO closure in preventing recurrent stroke is uncertain and the results of previous randomized clinical trials (RCTs) have been inconclusive. Hence, this study provides an updated meta-analysis of all RCTs comparing PFO closure with medical therapy for secondary prevention of cryptogenic stroke. METHODS: All RCTs were identified by a comprehensive literature search of PubMed, Embase, the Cochrane Collaboration Central Register of Controlled Trials, Scopus, and Clinicaltrials...
March 7, 2018: Cardiology Journal
Salih Kilic, Umut Kocabas, Levent Hurkan Can, Oğuz Yavuzgil, Mustafa Çetin, Mehdi Zoghi
BACKGROUND: Thrombolytic therapy is recommended for patients with acute ST-segment elevation myocardial infarction (STEMI) who cannot undergo primary percutaneous coronary intervention within the first 120 min. The aim of this study wasz to demonstrate the value of CHA₂DS₂-VASc and CHA₂DS₂-VASc-HS scores in predicting failed reperfusion in STEMI patients treated with thrombolytic therapy. METHODS: A total of 537 consecutive patients were enrolled in the study; 139 had failed thrombolysis while the remaining 398 fulfilled the criteria for successful thrombolysis...
March 7, 2018: Cardiology Journal
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