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Cardiology Journal

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https://www.readbyqxmd.com/read/29774520/implantation-of-bioresorbable-scaffolds-under-guidance-of-optical-coherence-tomography-feasibility-and-pilot-clinical-results-of-a-systematic-protocol
#1
Juan Luis Gutiérrez-Chico, Carlos Cortés, Michele Schincariol, Ula Limon, Meric Yalcinli, María-Alexandra Durán-Cortés, Milosz Jaguszewski
BACKGROUND: We hypothesise that a comprehensive optical coherence tomography (OCT)-guided implantation protocol for bioresorbable scaffolds (BRS) might improve expansion and apposition, thus translating into better clinical outcomes, particularly reducing thrombotic events. METHODS: Patients considered suitable for BRS therapy in de novo coronary lesions underwent OCT. The predominant type of plaque was classified as lipidic, fibrous or calcific, undergoing tailored plaque preparation accordingly...
May 18, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29745970/mechanical-efficiency-of-high-versus-moderate-intensity-aerobic-exercise-in-coronary-heart-disease-patients-a-randomized-clinical-trial
#2
Koldobika Villelabeitia-Jaureguizar, Davinia Vicente-Campos, Alejandro Berenguel Senen, Verónica Verónica Hernández Jiménez, Lorena Lorena Ruiz Bautista, María Elvira Barrios Garrido-Lestache, Jose López Chicharro
BACKGROUND: Mechanical efficiency (ME) refers to the ability of an individual to transfer energy consumed by external work. A decreased ME, could represent an increased energy cost during exercise and may, therefore, be limited in terms of physical activity. This study aimed to compare the influence of two different exercise protocols: moderate continuous training (MCT) versus high intensity interval training (HIIT), as part of a cardiac rehabilitation program on ME values among coronary patients...
May 10, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29745969/comparison-of-short-term-clinical-outcomes-between-resolute-onyx-zotarolimus-eluting-stents-and-everolimus-eluting-stent-in-patients-with-acute-myocardial-infarction-results-from-the-korea-acute-myocardial-infarction-registry-kamir
#3
Yongcheol Kim, Sung Sik Oh, Myung Ho Jeong, Youngkeun Ahn, Ju Han Kim, Young Joon Hong, Doo Sun Sim, Min Chul Kim, Hyo-Soo Kim, Kyeong Ho Yun, Seok Kyu Oh, Chong Jin Kim, Myeong Chan Cho
BACKGROUND: There are few studies which compare the efficacy and safety of the Resolute Onyx zotarolimus-eluting stent (O-ZES) and everolimus-eluting stent (EES) in patients with acute myocardial infarction (AMI). Therefore, the present study aimed to compare clinical outcomes of O-ZES and EES in patients with AMI undergoing successful percutaneous coronary intervention (PCI). METHODS: From January 2016 to December 2016, the Korea Acute Myocardial Infarction Registry (KAMIR) enrolled 3,364 consecutive patients...
May 10, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29745968/the-long-noncoding-rna-thril-knockdown-protects-hypoxia-induced-injuries-of-h9c2-cells-through-regulating-mir-99a
#4
Jingwen Xia, Nianxin Jiang, Yansong Li, Yong Wei, Xuan Zhang
BACKGROUND: Myocardial infarction (MI) is a leading cause of disease with high morbidity and mortality worldwide. Recent studies have revealed that long non-coding RNAs (lncRNAs) are involved in heart disease pathogenesis. This study aimed to investigate the effect and the molecular basis of THRIL on hypoxia-injured H9C2 cells. METHODS: THRIL, miR-99a and Brahma-related gene 1 (Brg1) expression in H9C2 cells were altered by transient transfections. The cells were subjected to hypoxia for 4 h, and then the levels of THRIL, miR-99a and Brg1 were investigated...
May 10, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29718533/monotherapy-of-aspirin-or-warfarin-for-prevention-of-ischemic-stroke-in-low-risk-atrial-fibrillation-a-easter-asian-population-based-study
#5
Chieh-Yu Liu, Hui-Chun Chen
BACKGROUND: This study aimed to investigate the effectiveness of monotherapy aspirin and warfarin for stroke prevention in low-risk atrial fibrillation (AF) by using a population-based cohort study in Taiwan. METHODS: A newly diagnosed low-risk AF patient cohort were identified by using National Health Insurance Research Database (NHIRD) in Taiwan in 2008. The study cohort was observed with a follow-up of 2 years to examine the onset of ischemic stroke (IS) (to 2010)...
May 2, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29718532/the-subcutaneous-implantable-cardioverter-defibrillator-a-tertiary-center-experience
#6
Cesar Khazen, Peter Magnusson, Johannes Flandorfer, Christoph Schukro
BACKGROUND: The aim of the study was to evaluate subcutaneous implantable cardioverter-defibrillator (S-ICD) patients with regard to underlying etiology, peri-procedural outcome, appropriate/inappropriate shocks, and complications during follow-up. METHODS: All patients who underwent S-ICD implantation from February 2013 to March 2017 at an academic hospital in Vienna were included. Medical records were examined and follow-up interrogations of devices were conducted...
May 2, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29718531/loss-of-amigo2-causes-dramatic-damage-to-cardiac-preservation-after-ischemic-injury
#7
Xuhui Ma, Pengfei Hu, Haifeng Chen, Tianfu Fang
BACKGROUND: Recent studies have identified amphoterin-induced gene and open reading frame (AMIGO) 2. The role of AMIGO2 in tumour research is well-studied, but its role in ischemic heart diseases is seldom reported. In the present study, the role of AMIGO2 in myocardial infarction is under investigation for the first time. METHODS: For in vitro studies, cardiomyocytes (CMs) and endothelial cells (ECs) were isolated from both AMIGO2 knockout (KO) and WT mice. The apoptosis of CMs was tested after 48 h of ischemic stimulation...
May 2, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29718530/effect-of-lcz696-a-dual-angiotensin-receptor-neprilysin-inhibitor-on-isoproterenol-induced-cardiac-hypertrophy-fibrosis-and-hemodynamic-change-in-rats
#8
Toru Miyoshi, Kazufumi Nakamura, Daiji Miura, Masashi Yoshida, Yukihiro Saito, Satoshi Akagi, Yuko Ohno, Megumi Kondo, Hiroshi Ito
BACKGROUND: Recent clinical studies have shown that treatment with LCZ696, a complex containing the angiotensin receptor blocker valsartan and neprilysin inhibitor sacubitril, improves the prognosis of heart failure patients with a reduced ejection fraction. This study evaluated whether LCZ696 affects left ventricular hypertrophy, fibrosis, and hemodynamics in isoproterenol (ISO)-treated rats compared with valsartan alone. METHODS: Male Wistar rats received subcutaneous saline (n = 10), subcutaneous ISO (2...
May 2, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29718529/impact-of-left-atrial-appendage-closure-on-cardiac-functional-and-structural-remodeling-a-difference-in-difference-analysis-of-propensity-score-matched-samples
#9
Quang Tan Phan, Seung-Yong Shin, Ik-Sung Cho, Wang-Soo Lee, Hoyoun Won, Saima Sharmin, Dong-Young Lee, Tae-Ho Kim, Chee-Jeong Kim, Sang-Wook Kim
BACKGROUND: Although the safety and efficacy of left atrial appendage (LAA) closure (LAAC) in nonvalvular atrial fibrillation (NVAF) patients have been well documented in randomized controlled trials and real-world experience, there are limited data in the literature about the impact of LAAC on cardiac remodeling. The aim of the study was to examine the impact of LAAC on cardiac functional and structural remodeling in NVAF patients. METHOD: s: Between March 2014 and November 2016, 47 NVAF patients who underwent LAAC were included in this study (LAAC group)...
May 2, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29718528/established-and-potential-echocardiographic-markers-of-embolism-and-their-therapeutic-implications-in-patients-with-ischemic-stroke
#10
Paulina E Gąsiorek, Maciej Banach, Marek Maciejewski, Andrzej Głąbiński, Aleksandra Paduszyńska, Jacek Rysz, Agata Bielecka-Dąbrowa
Cardiogenic strokes comprised 11% of all strokes and 25% of ischemic strokes. An accurate identification of the cause of stroke is necessary in order to prepare an adequate preventive strategy. In this review the confirmed and potential causes of embolic strokes are presented, which can be detected in echocardiography in the context of present treatment guidelines and gaps in evidence. There remains a need for further studies assessing the meaning of potential cardiac sources of embolism and establishment of rules for optimal medical prevention (antiplatelet therapy [APT] vs...
May 2, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29671864/treatment-of-patients-with-acute-coronary-syndrome-recommendations-for-medical-emergency-teams-focus-on-antiplatelet-therapies-updated-experts-standpoint
#11
Jacek Kubica, Piotr Adamski, Przemysław Paciorek, Jerzy R Ładny, Zbigniew Kalarus, Waldemar Banasiak, Wacław Kochman, Jarosław Gorący, Beata Wożakowska-Kapłon, Eliano Pio Navarese, Andrzej Kleinrok, Robert Gil, Maciej Lesiak, Jarosław Drożdż, Aldona Kubica, Krzysztof J Filipiak, Jarosław Kaźmierczak, Aleksander Goch, Stefan Grajek, Andrzej Basiński, Łukasz Szarpak, Grzegorz Grześk, Piotr Hoffman, Wojciech Wojakowski, Zbigniew Gąsior, Sławomir Dobrzycki, Jolanta M Siller-Matula, Adam Witkowski, Wiktor Kuliczkowski, Marcin Gruchała, Dariusz Timler, Grzegorz Opolski, Dariusz Dudek, Jacek Legutko, Marzenna Zielińska, Jarosław Wójcik
A group of Polish experts in cardiology and emergency medicine, encouraged by the European Society of Cardiology (ESC) guidelines, have recently published common recommendations for medical emergency teams regarding the pre-hospital management of patients with acute coronary syndrome. Due to the recent publication of the 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation and 2017 focused update on dual antiplatelet therapy in coronary artery disease the current panel of experts decided to update the previous standpoint...
April 19, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29671863/trends-in-hypertension-prevalence-awareness-treatment-and-control-among-polish-adults-75-years-and-older-during-2007-2014
#12
Arkadiusz A Niklas, Anna Flotyńska, Tomasz Zdrojewski, Andrzej Pająk, Roman Topór-Mądry, Paweł Nadrowski, Maria Polakowska, Magdalena Kwaśniewska, Aleksandra Puch-Walczak, Wojciech Bielecki, Krystyna Kozakiewicz, Wojciech Drygas, Andrzej Tykarski
BACKGROUND: The aim of this study was to assess changes in the prevalence, awareness and treatment of hypertension and its effectiveness between 2007 (WOBASZ Senior study) and 2013-2014 (WOBASZ II) in a sample of the Polish population over the age of 75 years. METHODS: Sampling had three stages, stratified according to voivodeships, type of community, and gender. Finally, the WOBASZ II study included 467 persons (290 women and 177 men). For a comparison of the data, 1096 persons (538 women and 554 men) examined in the WOBASZ Senior study were used...
April 19, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29671862/predictors-of-periprocedural-complications-in-patients-undergoing-percutaneous-coronary-interventions-within-coronary-bypass-grafts
#13
Rafał A Januszek, Artur Dziewierz, Zbigniew Siudak, Tomasz Rakowski, Dariusz Dudek, Stanisław Bartuś
BACKGROUND: During the first decade following the coronary bypass grafting, at least 10 of the patients require percutaneous coronary interventions (PCI) due to graft failure. Saphenous vein grafts (SVG) are innately at a higher risk of periprocedural complications. The present study aimed to investigate predictors of periprocedural complications of PCI within coronary artery bypass grafts. METHODS: This study analyzed data gathered in the Polish National Registry (ORPKI) between January 2015 and December 2016...
April 19, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29671861/p2y12-antagonist-ticagrelor-inhibits-the-release-of-procoagulant-extracellular-vesicles-from-activated-platelets-preliminary-results
#14
Aleksandra Gasecka, Rienk Nieuwland, Edwin van der Pol, Najat Hajji, Agata Ćwiek, Kinga Pluta, Michał Konwerski, Krzysztof J Filipiak
BACKGROUND: Activated platelets release platelet extracellular vesicles (PEVs). Adenosine diphosphate (ADP) receptors P2Y1 and P2Y12 both play a role in platelet activation, The present hypothesis herein is that the inhibition of these receptors may affect the release of PEVs. METHODS: Platelet-rich plasma from 10 healthy subjects was incubated with saline, P2Y1 antagonist MRS2179 (100 µM), P2Y12 antagonist ticagrelor (1 µM), and a combination of both antagonists...
April 19, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29611175/initial-experience-with-the-subcutaneous-implantable-cardioverter-defibrillator-with-the-real-costs-of-hospitalization-analysis-in-a-single-polish-center
#15
Marcin Grabowski, Monika Gawałko, Marcin Michalak, Andrzej Cacko, Michał Kowara, Agnieszka Kołodzińska, Łukasz Januszkiewicz, Paweł Balsam, Laura Vitali Serdoz, Joachim Winter, Grzegorz Opolski
BACKGROUND: The recent introduction of an entirely subcutaneous implantable cardioverter-defibrillator (S-ICD) represents an important progress in the defibrillation technology towards a less invasive approach. This is a single-center observational study of S-ICD implantations in Poland. METHODS: The S-ICD was implanted in 11 patients with standard indications for an ICD. Patients in whom the device was implanted were evaluated for adverse events and device function at hospital discharge...
April 3, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29611174/epidemiology-and-chronobiology-of-out-of-hospital-cardiac-arrest-in-a-subpopulation-of-southern-poland-a-two-year-observation
#16
Stanislaw Szczerbinski, Jakub Ratajczak, Piotr Lach, Jakub Rzeszuto, Przemyslaw Paciorek, Joanna Karlowska-Pik, Bartosz Ziemkiewicz, Malgorzata Jasiewicz, Aldona Kubica
BACKGROUND: Although recent studies indicate temporal variations in the incidence of out-of-hospital cardiac arrest (OHCA), the Polish experience in this research is scarce to date. Epidemiology of OHCA and circadian is evaluated herein, weekly and seasonal variations of OHCA frequency among the adult population of the Opole district, Poland. METHODS: The retrospective analysis of 815 OHCA cases with presumed cardiac etiology was made based on dispatch cards from the Emergency Medical Center in Opole registered during a 2 year period (2006-2007)...
April 3, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29611173/the-relationship-between-pulse-waveform-analysis-indices-endothelial-function-and-clinical-outcomes-in-patients-with-peripheral-artery-disease-treated-using-percutaneous-transluminal-angioplasty-during-a-one-year-follow-up-period
#17
Paweł S Kaczmarczyk, Paweł Maga, Rafał Niżankowski, Rafał Januszek, Marzena Frołow, Mikołaj Maga, Jolanta Kościelniak, Andrzej Belowski
BACKGROUND: The aim of the current study was to assess the relationship between potential predictors of clinical outcomes after percutaneous transluminal angioplasty (PTA) of peripheral arteries during a one-year follow-up. Indices of endothelial function (EF), arterial pulse waveform analysis (aPWA) and markers of peripheral arteries ischemia were among those mostly examined. METHODS: The study comprised of 72 individuals with PAD who underwent PTA of the peripheral arteries...
April 3, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29611172/prevention-of-in-stent-restenosis-with-endothelial-progenitor-cell-epc-capture-stent-placement-combined-with-regional-epc-transplantation-an-atherosclerotic-rabbit-model
#18
You-Hua Huang, Qiang Xu, Tao Shen, Jian-Ke Li, Jing-Yu Sheng, Hong-Jian Shi
BACKGROUND: Even with drug-eluting stents, the risk of in-stent restenosis (ISR) remains high. The goal of this study was to investigate the use of an endothelial progenitor cell (EPC) capture stent plus regional EPC transplantation to reduce the ISR rate. METHODS: Endothelial progenitor cell capture stents were fabricated using fibrin gel and anti-CD34 plus anti-VEGFR-2 dual antibodies. Twenty male New Zealand white rabbits established as an atherosclerotic model were randomly divided into two groups: group 1 (n = 10), in which EPC capture stents were deployed into the right iliac artery; and group 2 (n = 10), in which sirolimus-eluting stents were placed...
April 3, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29611171/percutaneous-renal-artery-denervation-in-patients-with-chronic-systolic-heart-failure-a-randomized-controlled-trial
#19
Jun-Qing Gao, Wei Yang, Zong-Jun Liu
B: ACKGROUND: Renal denervation (RDN) is as an effective treatment for heart failure, but its effects on cardiac function of patients with heart failure (HF) are not well documented. Here, the aim was to investigate RDN's effect on patients with chronic systolic HF, by conducting a single-center, prospective, randomized, and controlled study. M: ETHODS: Sixty patients with chronic systolic HF were randomly assigned to the RDN or control groups, receiving percutaneous catheter-based RDN with radiofrequency ablation and drug treatment respectively...
April 3, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29611170/feasibility-of-zero-or-near-zero-fluoroscopy-during-catheter-ablation-procedures
#20
Laurent M Haegeli, Linda Stutz, Mohammed Mohsen, Thomas Wolber, Corinna Brunckhorst, Chol-Jun On, Firat Duru
BACKGROUND: Awareness of risks associated with radiation exposure to patients and medical staff has significantly increased. It has been reported before that the use of advanced three-dimensional electro-anatomical mapping (EAM) system significantly reduces fluoroscopy time, however this study aimed for zero or near zero fluoroscopy ablation to assess its feasibility and safety in ablation of atrial fibrillation (AF) and other tachyarrhythmias in a "real world" experience of a single tertiary care center...
April 3, 2018: Cardiology Journal
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