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Journal of the Mechanical Behavior of Biomedical Materials

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https://www.readbyqxmd.com/read/28432998/non-ideal-effects-in-bending-response-of-soft-substrates-covered-with-biomimetic-scales
#1
Ranajay Ghosh, Hamid Ebrahimi, Ashkan Vaziri
Biomimetic scales are known to substantially alter the mechanics response of the underlying substrate engendering complex nonlinearities that can manifest even in small deformations due to scales interaction. This interaction is typically modeled using a-priori homogenization with an enforced periodicity of engagement. Such a framework is fairly useful especially when dealing with the structural length scale which is at least one order of magnitude greater than the scales themselves since individual tracking of a large number of scales become insurmountable...
April 15, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28432999/effect-of-intra-oral-aging-on-t%C3%A2-m-phase-transformation-microstructure-and-mechanical-properties-of-y-tzp-dental-ceramics
#2
Luciana Meireles Miragaya, Renato Bastos Guimarães, Rodrigo Othávio de Assunção E Souza, Glauco Dos Santos Botelho, José Guilherme Antunes Guimarães, Eduardo Moreira da Silva
The aim of the present study was to evaluate the influence of intra-oral aging on the tetragonal-to-monoclinic (t→m) phase transformation of two Y-TZP dental ceramics - Lava Frame (Frame) and Lava Plus (Plus) - and determine the impact of this response on their microstructures and mechanical properties: flexural strength, Young's modulus, microhardness and fracture toughness. Standardized ceramic specimens were analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM) and atomic force microscopy (AFM)...
April 13, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28433000/elastic-moduli-of-electrospun-mats-importance-of-fiber-curvature-and-specimen-dimensions
#3
Vijay Kumar, Amit Rawal
Success of tissue engineering relies on the architecture and properties of porous scaffolds. Electrospun nonwoven scaffolds in the form of mats are unique materials due to large surface area to volume ratio, high porosity, versatility in surface functionalities and excellent mechanical properties. Maneuvering the mechanical behavior of the electrospun mat is a major challenge both from theoretical and experimental perspectives. Herein, we report a two-dimensional (2D) analytical model of normalized elastic moduli of electrospun mats by formulating a relationship with the governing fiber and structural parameters...
April 12, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28431361/uncertainty-quantification-and-validation-of-3d-lattice-scaffolds-for-computer-aided-biomedical-applications
#4
Recep M Gorguluarslan, Seung-Kyum Choi, Christopher J Saldana
A methodology is proposed for uncertainty quantification and validation to accurately predict the mechanical response of lattice structures used in the design of scaffolds. Effective structural properties of the scaffolds are characterized using a developed multi-level stochastic upscaling process that propagates the quantified uncertainties at strut level to the lattice structure level. To obtain realistic simulation models for the stochastic upscaling process and minimize the experimental cost, high-resolution finite element models of individual struts were reconstructed from the micro-CT scan images of lattice structures which are fabricated by selective laser melting...
April 12, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28414986/modelling-dental-implant-extraction-by-pullout-and-torque-procedures
#5
D Rittel, A Dorogoy, K Shemtov-Yona
Dental implants extraction, achieved either by applying torque or pullout force, is used to estimate the bone-implant interfacial strength. A detailed description of the mechanical and physical aspects of the extraction process in the literature is still missing. This paper presents 3D nonlinear dynamic finite element simulations of a commercial implant extraction process from the mandible bone. Emphasis is put on the typical load-displacement and torque-angle relationships for various types of cortical and trabecular bone strengths...
April 11, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28412646/a-longitudinal-study-of-the-mechanical-properties-of-injured-brain-tissue-in-a-mouse-model
#6
Yuan Feng, Yuan Gao, Tao Wang, Luyang Tao, Suhao Qiu, Xuefeng Zhao
Mechanical properties of brain tissue are crucial to understand the mechanism of traumatic brain injury (TBI). Over the past several decades, most of the studies focused on healthy brain tissues, while few of them are about the injured tissues. Therefore, limited knowledge is known about the mechanical properties of the injured brain tissues. In this study, we used an in vivo mouse model with a weight drop device to study injured brain tissues. Around the injury site, mechanical properties of the injured, neighboring, and the corresponding contralateral regions of interest (ROIs) were measured over five temporal points by indentation...
April 8, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28411957/elevated-temperature-adhesion-of-bioinspired-polymeric-micropatterns-to-glass
#7
Viktoriia Barreau, Dan Yu, René Hensel, Eduard Arzt
Micropatterned polymer surfaces that operate at various temperatures are required for emerging technical applications such as handling of objects or space debris. As the mechanical properties of polymers can vary significantly with temperature, adhesion performance can exhibit large variability. In the present paper, we experimentally study temperature effects on the adhesion of micropatterned adhesives (pillar length 20µm, aspect ratios 0.4 and 2) made from three different polymers, i.e., polydimethylsiloxane (PDMS), perfluoropolyether dimethacrylate (PFPEdma), and polyurethane (PU-ht)...
April 7, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28411549/stability-of-knee-ligament-complex-of-thiel-embalmed-cadaver-compared-to-in-vivo-knee
#8
Florian Völlner, Ulrike Pilsl, Benjamin Craiovan, Florian Zeman, Michael Schneider, Michael Wörner, Joachim Grifka, Markus Weber
BACKGROUND: The first biomechanical evaluation of new implants is usually carried out with cadavers. Fixation of Thiel-embalmed cadavers is supposed to preserve the histological structure, colour and consistency of the tissue and has a low risk of infection and toxicity. However, the biomechanical properties of Thiel-fixated tissue are still unknown. The aim of this study was to quantify the effect of the Thiel-embalming method on the elastic properties of the ligament complex of the knee compared to in vivo knees during total knee arthroplasty...
April 7, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28411548/the-production-of-injectable-hydrazone-crosslinked-gellan-gum-hyaluronan-hydrogels-with-tunable-mechanical-and-physical-properties
#9
Jennika Karvinen, Janne T Koivisto, Ilari Jönkkäri, Minna Kellomäki
Gellan gum (GG) has been proposed for use in tissue engineering (TE) due to its structural and functional similarities with alginate. The most traditional crosslinking methods of GG, ionical and photocrosslinking, have downsides such as loss of stability or phototoxicity, which can limit their use in certain applications. In this study, an alternative hydrazone crosslinking method is introduced. Hydrazone crosslinking is a simple method that produces no toxic reagents or side-products. The method enables the fabrication of injectable hydrogels...
April 7, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28437660/an-experimental-analysis-of-shell-failure-in-breast-implants
#10
N G Ramião, P S Martins, M L Barroso, D C Santos, A A Fernandes
Breast implant durability and the mechanisms of rupture are important topics in the medical community, for patients, manufactures and regulatory medical agencies. After concerns about the Poly Implant Prosthesis (PIP) implants, the need for understanding the adverse outcomes and the failure mode to improve the breast implants increased. The objective of this research is to analyze and describe the rupture characteristics of failed explanted PIP implants to study the modes and causes of rupture. Eleven explanted PIP implants were analyzed by visual inspection and scanning electron microscopy (SEM)...
April 6, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28411547/mechanical-properties-and-state-of-miscibility-in-poly-racd-l-lactide-co-glycolide-l-lactide-co-%C3%AE%C2%B5-caprolactone-blends
#11
S Petisco-Ferrero, A Etxeberria, J R Sarasua
Polymers based on lactic acid (PLA) are a very promising category of biopolymers. As they are multi-stimuli responsive, can, in many ways, positively interact with the host, stimulating the innate reparative machinery of the human body. Since biopolymers for medical applications are subject to restrictive regulations, blending stands out as an effective method for obtaining tailored properties within a reduced time to market if compared to synthesis. Hence, in this study a set of PDLGA/PLCL blends was obtained by means of thermoplastic techniques and then further characterized...
April 6, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28407571/thermally-induced-shape-memory-behavior-enzymatic-degradation-and-biocompatibility-of-pla-tpu-blends-effects-of-compatibilization
#12
S K Dogan, S Boyacioglu, M Kodal, O Gokce, G Ozkoc
Poly(lactic acid) (PLA)/thermoplastic polyurethane (TPU) blends were melt-mixed and compatibilized to investigate their biocompatibility, biodegradability and thermally induced shape memory properties. The blend compositions were PLA/TPU: 80/20 (20TPU) and PLA/TPU: 50/50 (50TPU). 1,4-phenylene diisocyanate (PDI) was used in order to compatibilize the components reactively. The PDI composition was 0.5, 1, 3% by weight. Biodegradability was assessed by enzymatic degradation tests. Biocompatibility was investigated through in-vitro cell-culture experiments...
April 6, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28390304/effect-of-freezing-storage-time-on-the-elastic-and-viscous-properties-of-the-porcine-tmj-disc
#13
Jose L Calvo-Gallego, Maria S Commisso, Jaime Domínguez, Eiji Tanaka, Javier Martínez-Reina
The correct characterisation of the articular disc of the temporomandibular joint (TMJ) is key to study the masticatory biomechanics. For the interval from extraction until testing, freezing is the most used preservation technique for biological tissues, but its influence on their behaviour is still unclear. An important error can be committed in the characterisation of such tissues if freezing has any effect on their mechanical properties. Thus, the aim of this study was to determine whether the freezing storage time causes any change in the mechanical properties of the TMJ discs...
April 4, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28399493/increasing-strength-of-a-biomedical-ti-nb-ta-zr-alloy-by-alloying-with-fe-si-and-o
#14
Josef Stráský, Petr Harcuba, Kristína Václavová, Klaudia Horváth, Michal Landa, Ondřej Srba, Miloš Janeček
Low-modulus biomedical beta titanium alloys often suffer from low strength which limits their use as load-bearing orthopaedic implants. In this study, twelve different Ti-Nb-Zr-Ta based alloys alloyed with Fe, Si and O additions were prepared by arc melting and hot forging. The lowest elastic modulus (65GPa) was achieved in the benchmark TNTZ alloy consisting only of pure β phase with low stability due to the 'proximity' to the β to α'' martensitic transformation. Alloying by Fe and O significantly increased elastic modulus, which correlates with the electrons per atom ratio (e/a)...
April 2, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28407572/synthesis-and-viscoelastic-characterization-of-microstructurally-aligned-silk-fibroin-sponges
#15
Debojyoti Panda, Subhajit Konar, Saumendra K Bajpai, A Arockiarajan
Silk fibroin (SF) is a model candidate for use in tissue engineering and regenerative medicine owing to its bio-compatible mechanochemical properties. Despite numerous advances made in the fabrication of various biomimetic substrates using SF, relatively few clinical applications have been designed, primarily due to the lack of complete understanding of its constitutive properties. Here we fabricate microstructurally aligned SF sponge using the unidirectional freezing technique wherein a novel solvent-processing technique involving Acetic acid is employed, which obviates the post-treatment of the sponges to induce their water-stability...
March 28, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28391171/a-two-scale-modeling-and-computational-framework-for-vibration-induced-raynaud-syndrome
#16
Yue Hua, Pierre Lemerle, Jean-François Ganghoffer
Hand-Arm Vibration syndrome (HAVS), usually caused by long-term use of hand-held power tools, can in certain manifestations alter the peripheral blood circulation in the hand-arm region. HAVS typically occurs after exposure to cold, causing an abnormally strong vasoconstriction of blood vessels. A pathoanatomical mechanism suggests that a reduction of the lumen of the blood vessels in VWF (Vibration White Finger) subjects, due to either hypertrophy or thickening of the vessel wall, may be at the origin of the disease...
March 28, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28376363/the-effect-of-post-sintering-treatments-on-the-fatigue-and-biological-behavior-of-ti-6al-4v-eli-parts-made-by-selective-laser-melting
#17
M Benedetti, E Torresani, M Leoni, V Fontanari, M Bandini, C Pederzolli, C Potrich
Fatigue resistance and biocompatibility are key parameters for the successful implantation of hard-tissue prostheses, which nowadays are more and more frequently manufactured by selective laser melting (SLM). For this purpose, the present paper is aimed at investigating the effect of post-sintering treatments on the fatigue behavior and biological properties of Ti samples produced by SLM. After the building process, all samples are heat treated to achieve a complete stress relief. The remaining ones are tribofinished with the aim of reducing the surface roughness of the as-sintered condition...
March 28, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28376362/incorporation-of-plla-micro-fillers-for-mechanical-reinforcement-of-calcium-phosphate-cement
#18
Antonio G B Castro, Alessandro Polini, Zohal Azami, Sander C G Leeuwenburgh, John A Jansen, Fang Yang, Jeroen J J P van den Beucken
Calcium phosphate cements (CPCs) are biocompatible, resorbable, injectable and osteoconductive. Those properties render such materials suitable for applications where bone repair and regeneration is required However, their brittle nature limits their application only to non-load-bearing applications. The incorporation of long polymeric fibers can improve the mechanical properties of CPCs, but aggregation is a major problem. Instead, short polymeric fillers can be easily dispersed in the cement matrix, but their reinforcing effect has not been studied yet...
March 28, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28371700/graphite-nanoplatelets-modified-pla-pcl-effect-of-blend-ratio-and-nanofiller-localization-on-structure-and-properties
#19
Ivan Kelnar, Jaroslav Kratochvíl, Ludmila Kaprálková, Alexander Zhigunov, Martina Nevoralová
Structure and properties of poly(lactic acid) (PLA)/poly (ɛ-caprolactone) (PCL) influenced by graphite nanoplatelets (GNP) were studied in dependence on blend composition. Electron microscopy indicates predominant localization of GNP in PCL. GNP-induced changes in viscosity hinder refinement of PCL inclusions, support PCL continuity in the co-continuous system, and lead to reduction of PLA inclusions size without GNP being present at the interface in the PCL-matrix blend. Negligible differences in crystallinity of both phases indicate that mechanical behaviour is mainly influenced by reinforcement and GNP-induced changes in morphology...
March 28, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28365543/hyper-elastic-modeling-and-mechanical-behavior-investigation-of-porous-poly-d-l-lactide-nano-hydroxyapatite-scaffold-material
#20
Quan Feng Han, Ze Wu Wang, Chak Yin Tang, Ling Chen, Chi Pong Tsui, Wing Cheung Law
Poly-D-L-lactide/nano-hydroxyapatite (PDLLA/nano-HA) can be used as the biological scaffold material in bone tissue engineering as it can be readily made into a porous composite material with excellent performance. However, constitutive modeling for the mechanical response of porous PDLLA/nano-HA under various stress conditions has been very limited so far. In this work, four types of fundamental compressible hyper-elastic constitutive models were introduced for constitutive modeling and investigation of mechanical behaviors of porous PDLLA/nano-HA...
March 28, 2017: Journal of the Mechanical Behavior of Biomedical Materials
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