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Journal of the Mechanical Behavior of Biomedical Materials

Barbara Zupančič
Knowing the real material properties of brain tissue is of great importance when it comes to the precise prediction of its mechanical response. The efficiency of these procedures depends on the adequacy of experimental data and the analytical and numerical tools utilized. In this study, we combine existing approaches within the theory of viscoelasticity in order to predict the frequency-dependent behaviour of the porcine brain from the known stress relaxation data. Time-strain superposition is applied to the brain shear relaxation segments for the construction of the long-term master curve in the linear viscoelastic range...
July 4, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Seyyed M H Haddad, Sandeep S Dhaliwal, Brian W Rotenberg, Abbas Samani, Hanif M Ladak
Finite element (FE)-based biomechanical simulations of the upper airway are promising computational tools to study abnormal upper airway deformations under obstructive sleep apnea (OSA) conditions and to help guide minimally invasive surgical interventions in case of upper airway collapse. To this end, passive biomechanical properties of the upper airway tissues, especially oropharyngeal soft tissues, are indispensable. This research aimed at characterizing the linear elastic mechanical properties of the oropharyngeal soft tissues including palatine tonsil, soft palate, uvula, and tongue base...
July 3, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Shanpeng Li, Yun Zhang, Xiaoxiao Dou, Pingcheng Zuo, Jianlin Liu
With the evolution for several millions of years, leeches have developed a perfect capability to resist mechanical loads, which provides many inspirations to engineer new materials and new devices. To uncover the mechanism of its strong survival ability, several mechanical approaches, such as compression, tension, adhesion, impact and blood suction experiments were tried. Our experimental results show that a leech (Hirudo nipponia) can surprisingly withstand a compressive force of nearly 106 times its body weight...
July 2, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Daniela Warnecke, Svenja Stein, Melanie Haffner-Luntzer, Luisa de Roy, Nick Skaer, Robert Walker, Oliver Kessler, Anita Ignatius, Lutz Dürselen
Meniscal injury is typically treated surgically via partial meniscectomy, which has been shown to cause cartilage degeneration in the long-term. Consequently, research has focused on meniscal prevention and replacement. However, none of the materials or implants developed for meniscal replacement have yet achieved widespread acceptance or demonstrated conclusive chondroprotective efficacy. A redesigned silk fibroin scaffold, which already displayed promising results regarding biocompatibility and cartilage protection in a previous study, was characterised in terms of its biomechanical, structural and biological functionality to serve as a potential material for permanent partial meniscal replacement...
June 30, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Nilormi Biswas, Aniruddha Samanta, Soumik Podder, Chandan Kumar Ghosh, Jiten Ghosh, Mitun Das, Awadesh Kumar Mallik, Anoop Kumar Mukhopadhyay
Here we report for the very first time the synthesis of 100% phase pure calcium silicate nanoparticles (CSNPs) of the α-wollastonite phase without using any surfactant or peptizer at the lowest ever reported calcination temperature of 850 °C. Further, the phase purity is confirmed by quantitative phase analysis. The nano-network like microstructure of the CSNPs is characterized by FTIR, Raman, XRD, FESEM, TEM, TGA, DSC etc. techniques to derive the structure property correlations. The performance efficacies of the CSNPs against gram-positive e...
June 30, 2018: Journal of the Mechanical Behavior of Biomedical Materials
R R Behera, A Das, D Pamu, L M Pandey, M R Sankar
Biphasic calcium phosphate (BCP) consists of hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP). BCP is mainly used in artificial tooth and bone implants due to higher protein adsorption and osteoinductivity compared to HA alone. Although, many studies have been investigated on radio frequency (RF) magnetron sputtering of HA on Ti and its alloy, however, limited studies are available on BCP coating by this process and its bioactivity and adhesion behavior. Thus, in order to obtain a better understanding and applications of BCP films, RF magnetron sputtering is used to deposit BCP films on Ti-6Al-4V in the present study...
June 29, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Yanni Zhang, Ying Chen, Hongchao Kou, Pengfei Yang, Yanen Wang, Tingli Lu
To improve the bone healing efficiency of porous titanium implants, desired biological properties of implants are mandatory, involving bioactivity, osteoconductivity, osteoinductivity and a stable environment. In this study, bare porous titanium (abbr. pTi) with the porosity of 70% was fabricated by vacuum diffusion bonding of titanium meshes. Hydroxyapatite-coated pTi (abbr. Hap-pTi) was obtained by successively subjecting pTi to alkali heat treatment, pre-calcification and simulated body fluid. Both pTi and Hap-pTi were respectively implanted into the tibia defect model (ϕ10 mm × 6 mm) in New Zealand white rabbits, then subjected to non-invasively axial compressive loads at high-magnitude low-frequency (HMLF), which were denoted as F-pTi and F-Hap-pTi, respectively...
June 28, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Alessandro Navacchia, Chadd W Clary, Xuzheng Han, Kevin B Shelburne, Abraham P Wright, Paul J Rullkoetter
Patellar complications after total knee replacement (TKR), such as maltracking, fracture, wear, and loosening, can lead to implant failure and revision surgery. However, few in vitro patellofemoral durability tests for the implanted joint have been developed. Existing standards for patellofemoral loading profiles (ISO 14243-5, draft) are generic (not implant-specific) and do not include patient variability. The goal of this study was to derive implant-specific loading profiles to simulate a motor task that reaches high knee flexion and include patient variability...
June 28, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Fabiana Gullotta, Daniela Izzo, Francesca Scalera, Barbara Palazzo, Ivan Martin, Alessandro Sannino, Francesca Gervaso
Articular cartilage regeneration is still an open challenge in the field of tissue engineering. Although autologous chondrocytes seeded on collagen scaffolds (CSs) have already showed interesting results in the long-term repair of chondral lesions, they are not exempt from disadvantages that could be overcome using mesenchymal stem cells (MSCs). The ability of polymeric scaffolds to support MSCs proliferation and differentiation has been widely documented. However, few studies assessed their mechanical performances and additionally performing a single mechanical test, i...
June 28, 2018: Journal of the Mechanical Behavior of Biomedical Materials
E Roitero, M Anglada, F Mücklich, E Jiménez-Piqué
The aim of this work is to test the mechanical properties of dental zirconia surfaces patterned with Nd:YAG laser interference (λ = 532 nm and 10 ns pulse). The laser treatment produces an alteration of the topography, engraving a periodic striped pattern. Laser-material interaction results mainly in thermal effects producing microcracking, phase transformation and texturization. The role of such microstructural modifications and collateral damage on the integrity and mechanical performances has been assessed...
June 28, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Matin Sadat Saneei Mousavi, Amir Hossein Karami, Mehrshad Ghasemnejad, Mohammadreza Kolahdouz, Faranak Manteghi, Farangis Ataei
Since the local, on demand, cancer therapy is a challenging clinical issue today, this paper presents the design, fabrication and characterization of a remotely controlled single reservoir drug delivery chip using Ionic Polymer Metal Composite (IPMC) actuator. Here, Drug release was externally programmed and controlled wirelessly on demand by a communication circuit. The transmitter and receiver circuits were designed to control the release/sealed status remotely even from 7 cm distance while the transmitter and receiver were coupled magnetically...
June 28, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Hoda Hatoum, Frederick Heim, Lakshmi Prasad Dasi
OBJECTIVE: This study aims at assessing the global dynamic behavior, elastic deformability, closing energy and turbulence of rigid versus deformable stented (RS vs DS) valve systems with deformable and rigid textile materials (DT vs RT) through studying the stent-valve interaction compared to a bioprosthetic material in transcatheter aortic valves (TAV). METHODS: Three 19 mm stented textile TAV designs (RS-DT, RS-RT and DS-RT) with different stent and leaflet properties were tested and compared with a control bioprosthetic TAV (RS-DB) in a left heart simulator flow loop under physiological pressure and flow...
June 28, 2018: Journal of the Mechanical Behavior of Biomedical Materials
T Y Wei, J C Huang, Chih-Yeh Chao, L L Wei, M T Tsai, Y H Chen
In order to develop Ti based alloys with promising biocompatibility and matching mechanical response with human bone, TiTaNb alloys with 15, 23 and 30 mass% Ta are designed and systematically examined in terms of microstructural evolution and mechanical response. The Ti-30mass%Ta-10mass%Nb is demonstrated to be satisfactory with an elastic modulus ~60 GPa, hardness ~3.1 GPa, and strength ~1250 MPa. The evolution trend of the resulting microstructure and phases as a function of Ta content and annealing temperature are established...
June 28, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Fupo He, Teliang Lu, Ye Tian, Xue Li, Fei Zuo, Xuetao Shi, Jiandong Ye
β-tricalcium phosphate (β-TCP) bioceramic, which is a prevalent bone graft, is deficient in mechanical strength and mediating the biological functions. In the present study, β-tricalcium phosphate composite bioceramics (TCP/SPNs) were prepared by introducing SrO-P2 O5 -Na2 O based (SPN) sintering additive. With increasing mole ratio of SrO to P2 O5 , the SPN tended to crystallize. In the liquid-phase sintering process, β-TCP reacted with SPN, producing new compounds. The difference in characteristic of SPN additive affected the compressive strength and cell-biological response of the fabricated TCP/SPNs...
June 28, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Yaxuan Liu, Da Bian, Yongwu Zhao, Yongguang Wang
To promote anti-corrosion property of chemically bonded phosphate ceramic coatings (CBPCs), the nano-TiO2 is selected as the reinforcement. Differential scanning calorimetry (DSC), X-ray diffraction (XRD), Scanning electron microscope (SEM), Energy Dispersive Spectrometer (EDS) and the electrochemical analysis are carried out to clarify the role of nano-TiO2 on the improvement of anti-corrosion performance. The experiments show that with the addition of nano-TiO2 , the curing temperature and the activation energy of the curing process increase, which allows longest reaction and positively drives curing reactions at elevated conversions...
June 28, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Chih-Hsun Lin, Yun-Chu Kao, Hsu Ma, Ruey-Yug Tsay
PURPOSE: The nonlinear pseudoelastic behavior of a native/decellularized vascular tissue is closely related to the detailed composition and microstructure of the extracellular matrix and is important in maintaining the patency of a small-caliber vascular graft. A commonly used enzyme-detergent based decellularization protocol is effective in cell component removal but it also changes the microstructure and composition of the decellularized tissues. Previous studies provide limited information to correlate the mechanical property change with the alterations in composition and microstructure in a decellularization process...
June 27, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Harkamaljot S Kandail, Setu D Trivedi, Armaan C Shaikh, Tanvir K Bajwa, Daniel P O'Hair, Arshad Jahangir, John F LaDisa
CoreValve is widely used in transcatheter aortic valve replacement, but the impact of its deployment location on hemodynamics is unexplored despite a potential role in subsequent aortic and coronary artery pathologies. The objectives of this investigation were to perform fluid-structure interaction (FSI) simulations for a 29 mm CoreValve deployed in annular vs supra-annular locations, and characterize resulting hemodynamics including velocity and wall shear stress (WSS). Patient-specific geometry was reconstructed from computed tomography scans and CoreValve was deployed using a finite element approach...
June 27, 2018: Journal of the Mechanical Behavior of Biomedical Materials
A Sharipova, S K Swain, I Gotman, D Starosvetsky, S G Psakhie, R Unger, E Y Gutmanas
An original fabrication route of high-strength bulk Fe-5Ag and Fe-10Ag nanocomposites with enhanced degradation rate is reported. Near fully dense materials with fine nanostructures and uniform distribution of Ag nanoparticles were obtained employing high energy attrition milling of Fe-Ag2 O powder blends followed by cold sintering - high pressure consolidation at ambient temperature that allowed the retention of the nanoscale structure. Annealing in hydrogen flow at 550 °C resulted in enhanced ductility without coarsening the nanostructure...
June 26, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Anastasia Beketova, Savvas Varitis, Eleana Kontonasaki, Triantafillia Zorba, Lambrini Papadopoulou, Nikolaos Kantiranis, Georgios S Theodorou, Konstantinos M Paraskevopoulos, Petros Koidis
The aim of this study was to evaluate microhardness and elastic modulus of a novel sol-gel derived dental ceramic - 58S bioactive glass composite (BP67: Bioactive Glass:33.3%, Dental Ceramic:66.7%) BP671 material by micro-indentation and to investigate its microstructure and bioactivity. The research hypotheses were that the values of microhardness (1) and elastic modulus (2) of the novel bioceramic composite and the commercial dental ceramic will be of the same order. The experimental sol-gel derived ceramics showed similar microstructural characteristics to a commercial feldspathic porcelain, and presence of additional calcium phosphate phases, which contributed its bioactivity...
June 26, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Rüdiger Hampe, Nina Lümkemann, Beatrice Sener, Bogna Stawarczyk
OBJECTIVES: To determine the Martens hardness parameters for five different classes of CAD/CAM restorative materials after storage in water and thermo-cycling. MATERIALS AND METHODS: Lithium disilicate ceramic IPS e.max CAD (EX), silicate ceramic IPS Empress CAD (EC), a polymer infiltrated interpenetrating network material (hybrid material) VITA Enamic (VE), two compact filled composites Lava Ultimate (LU), experimental material (EM), two low filled resin composites Katana Avencia (KA), Ambarino High-Class (AH) and ultra-low/unfilled acrylic polymers CAD-Temp (CT), Telio CAD (TC), breCAM...
June 25, 2018: Journal of the Mechanical Behavior of Biomedical Materials
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