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Journal of the Mechanical Behavior of Biomedical Materials

Di Huang, Lulu Niu, Jian Li, Jingjing Du, Yan Wei, Yinchun Hu, Xiaojie Lian, Weiyi Chen, Kaiqun Wang
In order to improve the osteogenic activity and mechanical strength of the guided bone regeneration (GBR) membrane for repairing bone defect, nano-hydroxyapatite/chitosan (nHA/CS) composite microspheres were prepared through in situ biomimetic method, then composite microspheres were incorporated into CS membrane. The morphologies and mechanical properties of the composite membranes were investigated through scanning electronic microscopy (SEM) and universal mechanical testing machine. The results show that the in situ biomimetic nHA/CS microspheres were embedded in CS membrane and were integrated tightly with CS matrix...
March 7, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Yao Lu, Shaoju Fu, Shuanglin Zhou, Ge Chen, Chaoting Zhu, Nannan Li, Ying Ma
Composite mesh with different materials composition could compensate for the drawbacks brought by single component mesh. Coating a membrane layer on the surface of macroporous mesh is a common method for preparing composite medical mesh. Electrospinning and dipping methods were introduced to form the two kinds of membrane-coated PP meshes (electro-mesh and dip-mesh); several properties were measured based on subcutaneous implantation model in rat. The results revealed that continuous tissue ingrowth could be observed for electro-mesh only with evidences of strength increase (electro-mesh: 0 week - 13...
February 28, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Bruno Henriques, Douglas Fabris, Júlio C M Souza, Filipe S Silva, Óscar Carvalho, Márcio C Fredel, Joana Mesquita-Guimarães
OBJECTIVES: The aim of this study was to evaluate the effect of laser surface structuring on the bond strength of feldspar-based porcelain to zirconia, as compared to conventional sandblasting treatment. MATERIALS AND METHODS: Thirty cylindrical zirconia substrates, previously sintered, were divided in three groups according to the type of surface conditioning: 1) sandblasting with 50 µm Al2 O3 ; 2) laser structuring (Ø25 µm holes); and 3) laser structuring (Ø50 µm holes)...
February 27, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Bingbing An, Dongsheng Zhang
Dentin is a biocomposite possessing complex hierarchical structure, which endows this hard tissue with excellent damage tolerance. In this study, crack growth in dentin at the microstructural scale is investigated and the synergistic effects of plastic deformation of intertubular dentin (ITD), elasticity and fracture properties of peritubular dentin (PTD), and fracture properties of PTD/ITD interface on the fracture of dentin are explored. A micromechanical model is developed, which captures the experimentally observed fracture process of dentin, i...
February 26, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Wenguang Li
Strain energy-based constitutive laws with damage effect were proposed by using existing both uniaxial tensile test and tubular biaxial inflation test data on the human great saphenous vein (GSV) segments. These laws were applied into GSV coronary artery bypass grafts (CABG) by employing a thin-walled vessel model to evaluate their passive biomechanical performance under coronary artery physiological conditions at a fixed axial pre-stretch. At a peak systolic pressure in 100-150 mmHg, a 20-33% GSV diameter dilation was predicted with the law based on tubular biaxial inflation test data and agreed well with 25% dilation in clinical observation in comparison with as small as 2-4% dilation estimated with the law based on uniaxial tensile test data...
February 23, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Yanjin Lu, Ling Ren, Xiongcheng Xu, Yang Yang, Songquan Wu, Jiasi Luo, Mingyu Yang, Lingling Liu, Danhong Zhuang, Ke Yang, Jinxin Lin
In the study, CoCrWCu alloys with differing Cu content (2, 3, 4 wt%) were prepared by selective laser melting using mixture powders consisting of CoCrW and Cu, aiming at investigating the effect of Cu on the microstructures, mechanical properties, corrosion behavior and cytotoxicity. The SEM observations indicated that the Cu content up to 3 wt% caused the Si-rich precipitates to segregate along grain boundaries and in the grains, and EBSD analysis suggested that the Cu addition decreased the recrystallization degree and increased the grain diameter and fraction of big grains...
February 23, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Zohreh Arabshahi, Isaac Oluwaseun Afara, Hayley Ruscoe Moody, Karsten Schrobback, Jamal Kashani, Nadine Fischer, Adekunle Oloyede, Travis Jacob Klein
The conventional mechanical properties of articular cartilage, such as compressive stiffness, have been shown to have limited capacity to distinguish visually normal from degraded cartilage samples. In this study, a new mechanical indentation framework for assessing functional properties of articular cartilage during loading/unloading, i.e. deformation and recovery, was established. The capacity of a ring-shaped indenter integrated with an ultrasound transducer to distinguish mechanically intact from proteoglycan-depleted tissue was investigated...
February 23, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Behzad Shiroud Heidari, Seyed Mohammad Davachi, Amin Hedayati Moghaddam, Javad Seyfi, Iman Hejazi, Razi Sahraeian, Hamid Rashedi
In this study, injection molding process of ultrahigh molecular weight polyethylene (UHMWPE) reinforced with nano-hydroxyapatite (nHA) was simulated and optimized through minimizing the shrinkage and warpage of the hip liners as an essential part of a hip prosthesis. Fractional factorial design (FFD) was applied to the design of the experiment, modeling, and optimizing the shrinkage and warpage of UHMWPE/nHA composite liners. The Analysis of variance (ANOVA) was applied to find the importance of operative parameters and their effects...
February 21, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Xi Gao, Menghao Chen, Xiaogang Yang, Lee Harper, Ifty Ahmed, Jiawa Lu
This paper presents a strain-based damage model to predict the stress-strain relationship and investigate the damage onset and evolution of the fibre and matrix of a fully bio-resorbable phosphate glass fibre reinforced composite under three-point bending. The flexural properties of the composite are crucial, particularly when it is employed as implant for long bone fracture. In the model, the 3D case of the strain and stress was used and the response of the undamaged material was assumed to be linearly elastic...
February 21, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Luciana D Trino, Erika S Bronze-Uhle, Amsaveni Ramachandran, Paulo N Lisboa-Filho, Mathew T Mathew, Anne George
Titanium (Ti) is widely used in biomedical devices due to its recognized biocompatibility. However, implant failures and subsequent clinical side effects are still recurrent. In this context, improvements can be achieved by designing biomaterials where the bulk and the surface of Ti are independently tailored. The conjugation of biomolecules onto the Ti surface can improve its bioactivity, thus accelerating the osteointegration process. Ti was modified with TiO2 , two different spacers, 3-(4-aminophenyl) propionic acid (APPA) or 3-mercaptopropionic acid (MPA) and dentin matrix protein 1 (DMP1) peptides...
February 21, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Qianqian Wu, Li Ma, Qiunan Liu, Lina Feng, Zhenyu Wang, Arne Ohrndorf, Hans-Jürgen Christ, Jian Xiong
A skull fracture, due to a composition of typical lightweight cellular structures, is the most common type of traumatic brain injury. This paper presents a systematic investigation on the failure mechanism and energy absorption of skull cellular bones under low- and medium-velocity impact loadings. Non-destructive three-dimensional micro-computed tomography (Micro-CT) is utilized to scan samples of human skull cellular bones, and relevant structural parameters are obtained to reconstruct a finite element (FE) model of these bones...
February 20, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Indu Yadav, Suraj K Nayak, V S Sharan Rathnam, Indranil Banerjee, Sirsendu S Ray, Arfat Anis, Kunal Pal
The current study deals with the preparation and the characterization of the PVA-CMT-GO films. The PVA-CMT film was translucent in nature and smooth to touch. The addition of GO resulted in the formation of agglomerated structures. XRD studies suggested that the incorporation of GO increased the average crystallite size. The mechanical properties of the films as determined by stress relaxation studies suggested that all the films were viscoelastic in nature. The drug release study showed a decrease in the amount of the drug release with the increase in the GO content...
February 20, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Zhenzhen Zhang, Jiawen Guo, Yali Sun, Beimin Tian, Xiaojuan Zheng, Ming Zhou, Lin He, Shaofeng Zhang
OBJECTIVES: The purpose of this study is to improve wear resistance and mechanical properties of lithium disilicate glass-ceramics by refining their crystal sizes. METHODS: After lithium disilicate glass-ceramics (LD) were melted to form precursory glass blocks, bar (N = 40, n = 10) and plate (N = 32, n = 8) specimens were prepared. According to the differential scanning calorimetry (DSC) of precursory glass, specimens G1-G4 were designed to form lithium disilicate glass-ceramics with different crystal sizes using a two-step thermal treatment...
February 20, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Marco Migliorati, Sara Drago, Domenico Dalessandri, Alberto Lagazzo, Fabio Gallo, Marco Capurro, Armando Silvestrini-Biavati
BACKGROUND: The clinical success of orthodontic miniscrews is strictly related to primary stability, which depends on bone viscoelastic properties too. In this study, we evaluated the short time mechanical response of native bone to miniscrews, by a laboratory test based on dynamic loading. METHODS: Thirty-six segments of porcine ribs were first scanned by cone-beam computerized tomography to obtain insertion-site cortical thickness, cortical and marrow bone density...
February 19, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Marta Musioł, Sebastian Jurczyk, Michał Kwiecień, Anna Smola-Dmochowska, Marian Domański, Henryk Janeczek, Jakub Włodarczyk, Magdalena Klim, Joanna Rydz, Michał Kawalec, Michał Sobota
The semicrystalline poly(L-lactide) (PLLA) belongs to the materials with shape memory effect (SME) and as a bioresorbable and biocompatible polymer it have found many applications in medical and pharmaceutical field. Assessment of the SME impact on the polymer degradation profile plays crucial role in applications such as drug release systems or in regenerative medicine. Herein, the results of in vitro degradation studies of PLLA samples after SME full test cycle are presented. The samples were loaded and deformed in two manners: progressive and non-progressive...
February 19, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Bryant Heimbach, Beril Tonyali, Dianyun Zhang, Mei Wei
Bone fractures are some of the most common injuries annually, and many require a fixation device to help properly heal. The present study focuses on developing a bioresorbable composite that has high strength and stiffness for bone fixation applications. To achieve this, a design of experiments was performed, testing the effect of long fiber reinforcement type, matrix type, matrix amount, and particle reinforcement amount on the flexural properties of the composite. Based on these results, the ideal resorbable long fiber reinforcement, particle reinforcement, and matrix material are degummed silk fibroin, hydroxyapatite, and polylactic acid, respectively...
February 19, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Dipankar Choudhury, David Rebenda, Shinya Sasaki, Pavel Hekrle, Martin Vrbka, Min Zou
This study evaluates the impact of dimple shapes on lubricant film formation in artificial hip joints. Micro-dimples with 20-50 µm lateral size and 1 ± 0.2 µm depths were fabricated on CrCoMo hip joint femoral heads using a picosecond laser. Tribological studies were performed using a pendulum hip joint simulator to apply continuous swing flexion-extension motions. The results revealed a significantly enhanced lubricant film thickness (≥ 500 nm) with micro-dimpled prosthesis heads at equilibrium position after the lubricant film has fully developed...
February 17, 2018: Journal of the Mechanical Behavior of Biomedical Materials
S Jiang, L J Huang, Q An, L Geng, X J Wang, S Wang
Titanium-magnesium (Ti-Mg) composites with bicontinuous structure have been successfully fabricated by powder metallurgy and ultrasonic infiltration for biomaterial potential. In the composites, Ti phase is distributed continuously by sintering necks, while Mg phase is also continuous, distributing at the interconnected pores surrounding the Ti phase. The results showed that the fabricated Ti-Mg composites exhibited low modulus and high strength, which are very suitable for load bearing biomedical materials...
February 14, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Serhii Tkachenko, Miroslava Horynová, Mariano Casas-Luna, Sebastian Diaz-de-la-Torre, Karel Dvořák, Ladislav Celko, Jozef Kaiser, Edgar B Montufar
The present work studies the microstructure and mechanical performance of tricalcium phosphate (TCP) based cermet toughened by iron particles. A novelty arises by the employment of spark plasma sintering for fabrication of the cermet. Results showed partial transformation of initial alpha TCP matrix to beta phase and the absence of oxidation of iron particles, as well as a lack of chemical reaction between TCP and iron components during sintering. The values of compressive and tensile strength of TCP/Fe cermet were 3...
February 12, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Alka Jaggessar, Asha Mathew, Hongxia Wang, Tuquabo Tesfamichael, Cheng Yan, Prasad Kdv Yarlagadda
The application of orthopaedic implants is associated with risks of bacterial infection and long-term antibiotic therapy. This problem has led to the study of implants with nano-textured surfaces as a method of inhibiting bacterial adhesion and reducing implant failure due to infection. In this research, various nano-textured surfaces of TiO2 were synthesised using hydrothermal synthesis, by varying NaOH concentration, reaction time and reaction temperature. Their correlations to mechanical, morphological, bactericidal and osteogenic properties of the surfaces were investigated...
February 12, 2018: Journal of the Mechanical Behavior of Biomedical Materials
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