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Journal of the Mechanical Behavior of Biomedical Materials

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https://www.readbyqxmd.com/read/28535395/a-zinc-chloride-doped-adhesive-facilitates-sealing-at-the-dentin-interface-a-confocal-laser-microscopy-study
#1
Manuel Toledano, Raquel Osorio, Estrella Osorio, Inmaculada Cabello, Manuel Toledano-Osorio, Fátima S Aguilera
The aim of this study was to ascertain the effect of Zn-doping of dental adhesives and mechanical load cycling on the micromorphology of the resin-dentin interdiffusion zone (of sound and caries affected dentin). The investigation considered two different Zn-doped adhesive approaches and evaluated the interface using a doubled dye fluorescent technique and a calcium chelator fluorophore under a confocal laser scanning microscopy. Sound and carious dentin-resin interfaces of unloaded specimens were deficiently resin-hybridized, in general...
May 19, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28550763/mechanical-properties-of-a-nanoporous-membrane-used-in-implantable-medical-devices-correlation-between-experimental-characterization-and-2d-numerical-simulation
#2
F Cristofari, B Piotrowski, R Pesci
Nanoporous membranes are used for the elaboration of implantable medical devices. In order to guaranty their integrity after implantation in a patient body, it is necessary to characterize the microstructure and the mechanical behavior of such membranes. They present randomly distributed pores around 1µm in diameter at the surface. X-ray nanotomography permits to get the geometry of the pores through the thickness with a reduction of the diameter in the core. A multiscale study is done to characterize the membranes: macroscopic tensile tests permit to get the behavior law of the non porous material and in situ tensile tests are carried on in a Scanning Electron Microscope in order to observe the evolution of pores and cracks during loading...
May 18, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28550764/mechanical-properties-of-crossed-lamellar-structures-in-biological-shells-a-review
#3
REVIEW
X W Li, H M Ji, W Yang, G P Zhang, D L Chen
The self-fabrication of materials in nature offers an alternate and powerful solution towards the grand challenge of designing advanced structural materials, where strength and toughness are always mutually exclusive. Crossed-lamellar structures are the most common microstructures in mollusks that are composed of aragonites and a small amount of organic materials. Such a distinctive composite structure has a fracture toughness being much higher than that of pure carbonate mineral. These structures exhibiting complex hierarchical microarchitectures that span several sub-level lamellae from microscale down to nanoscale, can be grouped into two types, i...
May 17, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28527353/mechanical-behavior-of-the-abdominal-aortic-aneurysm-assessed-by-biaxial-tests-in-the-rat-xenograft-model
#4
Louise Marais, Mustapha Zidi
This paper addresses the mechanical biaxial behavior of degraded arteries obtained by the rat xenograft model. For that, a pressure myograph was used to perform extension-inflation tests on abdominal aortic aneurysms (AAAs). Furthermore, residual stresses in the aneurismal wall were assessed by opening angle tests. Thus, the changes in mechanical behavior between native murine aortas, decellularized guinea pig aortas (the grafts) and degraded aortas (AAAs) were investigated. It was shown that decellularized and degraded aortas exhibited a different mechanical behavior than native murine aortas...
May 12, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28525820/sensing-inhomogeneous-mechanical-properties-of-human-corneal-descemet-s-membrane-with-afm-nano-indentation
#5
Rosa Di Mundo, Giuseppina Recchia, Mohit Parekh, Alessandro Ruzza, Stefano Ferrari, Giuseppe Carbone
The paper describes a highly space-resolved characterization of the surface mechanical properties of the posterior human corneal layer (Descemet's membrane). This has been accomplished with Atomic Force Microscopy (AFM) nano-indentation by using a probe with a sharp tip geometry. Results indicate that the contact with this biological tissue in liquid occurs with no (or very low) adhesion. More importantly, under the same operating conditions, a broad distribution of penetration depth can be measured on different x-y positions of the tissue surface, indicating a high inhomogeneity of surface stiffness, not yet clearly reported in the literature...
May 10, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28521277/the-spatio-temporal-mechanical-environment-of-healthy-and-injured-human-cartilage-during-sustained-activity-and-its-role-in-cartilage-damage
#6
Saeed Miramini, David W Smith, Lihai Zhang, Bruce S Gardiner
Recently we presented a computational model of articular cartilage calibrated for normal human tissue explants. This model was able to capture the transient deformation of cartilage experiencing a cyclic load. The model takes into account the tension-compression nonlinearity of the cartilage and incorporates the dependency of the compressive stiffness and fluid permeability of cartilage on the deformation-dependent aggrecan concentration in cartilage tissue. As such it represents a leading constitutive model of articular cartilage...
May 10, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28505594/the-rheological-behavior-of-a-fast-setting-calcium-phosphate-bone-cement-and-its-dependence-on-deformation-conditions
#7
Erdem Şahin, Dilhan M Kalyon
Calcium phosphate cements are osteoconductive biomaterials that are widely used for bone repair and regeneration applications, including spinal fusion, vertebroplasty, khyphoplasty, cranioplasty and periodontal surgeries. The flow and deformation behavior (rheology) and injectability of the calcium phosphate bone cements to the treatment site are governed by the setting kinetics of the cement during which the initially flowable, viscous cement paste transforms into a rigid elastic solid. Here time-dependent development of the linear viscoelastic properties of a brushite-forming calcium phosphate cement are characterized and linked to the mechanism and kinetics of the setting reaction and to the injectability window available during the surgical applications of the cement...
May 10, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28522235/a-review-of-terrestrial-aerial-and-aquatic-keratins-the-structure-and-mechanical-properties-of-pangolin-scales-feather-shafts-and-baleen-plates
#8
Bin Wang, Tarah N Sullivan
Keratinous materials, omnipresent as the hard and durable epidermal appendages of animals, are one of the toughest biological materials. They exhibit diverse morphologies and structures that serve a variety of amazing and inspiring mechanical functions. In this work, we provide a review of representative terrestrial, aerial and aquatic keratinous materials, pangolin scales, feather shafts and baleen plates, and correlate their hierarchical structures to respective functions of dermal armor, flight material and undersea filter...
May 8, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28511106/mechanical-properties-and-numerical-simulation-of-sulcata-tortoise-carapace
#9
Nadda Jongpairojcosit, Petch Jearanaisilawong
Carapace of Sulcata tortoise acts as a natural shield that protects the body from natural predators. The carapace consists of four layers: keratin scutes, dorsal cortex, cancellous interior and ventral cortex. This study aims to investigate the load-bearing mechanisms of the carapace by characterizing the layers, measuring their mechanical properties and relating them to the macroscopic behavior under compression and bending loads. Test results indicate the influence of layers' morphology, especially porosity and structural compositions, on the macroscopic properties of the carapace...
May 8, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28501720/characterization-and-restoration-of-degenerated-ivd-function-with-an-injectable-in-situ-gelling-alginate-hydrogel-an-in-vitro-and-ex-vivo-study
#10
Emily A Growney Kalaf, Meghana Pendyala, J Gary Bledsoe, Scott A Sell
Intervertebral disc (IVD) degeneration is a naturally, irreparable process that causes loss in IVD hydration, cellularity, and, mechanical stability. Invasive surgical attempts to ease back pain and, radiculopathy have shown to cause increased degeneration along the rest, of the spine. Due to its highly tunable mechanical and degradation, properties, alginate is a viable option for a less-invasive injectable, repair for IVD degeneration. This study centers on the characterization, of in situ gelling alginate and subsequent injection into enzymatically, degraded motion segments...
May 7, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28501721/cortical-bone-elasticity-measured-by-resonant-ultrasound-spectroscopy-is-not-altered-by-defatting-and-synchrotron-x-ray-imaging
#11
X Cai, L Peralta, A Giron, L Helfen, C Olivier, F Peyrin, P Laugier, Q Grimal
In the study of mechanical properties of human bone, specimens may be defatted before experiments to prevent contamination and the risk of infections. High energy synchrotron radiation micro-computed tomography (SR-μCT) is a popular technique to study bone microstructure. However, little is known about the effects of defatting or irradiation during SR-μCT imaging on different elastic coefficients including shear and longitudinal moduli in different anatomical directions. In this work, these effects are evaluated on a set of 24 samples using resonant ultrasound spectroscopy (RUS), which allows one to accurately measure the complete set of elastic coefficients of cortical bone non destructively...
May 6, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28501719/colliding-jets-provide-depth-control-for-water-jetting-in-bone-tissue
#12
S den Dunnen, J Dankelman, G M Kerkhoffs, G Tuijthof
In orthopaedic surgery, water jet drilling provides several advantages over classic drilling with rigid drilling bits, such as the always sharp cut, absence of thermal damage and increased manoeuvrability. Previous research showed that the heterogeneity of bone tissue can cause variation in drilling depth whilst water jet drilling. To improve control over the drilling depth, a new method is tested consisting of two water jets that collide directly below the bone surface. The expected working principle is that after collision the jets will disintegrate, with the result of eliminating the destructive power of the coherent jets and leaving the bone tissue underneath the focal point intact...
May 6, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28500998/the-impact-of-surface-and-geometry-on-coefficient-of-friction-of-artificial-hip-joints
#13
Dipankar Choudhury, Martin Vrbka, Azuddin Bin Mamat, Ian Stavness, Chanchal K Roy, Rajshree Mootanah, Ivan Krupka
Coefficient of friction (COF) tests were conducted on 28-mm and 36-mm-diameter hip joint prostheses for four different material combinations, with or without the presence of Ultra High Molecular Weight Polyethylene (UHMWPE) particles using a novel pendulum hip simulator. The effects of three micro dimpled arrays on femoral head against a polyethylene and a metallic cup were also investigated. Clearance played a vital role in the COF of ceramic on polyethylene and ceramic on ceramic artificial hip joints. Micro dimpled metallic femoral heads yielded higher COF against a polyethylene cup; however, with metal on metal prostheses the dimpled arrays significantly reduced the COF...
May 6, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28499166/potential-biodegradable-zn-cu-binary-alloys-developed-for-cardiovascular-implant-applications
#14
Zibo Tang, Jialin Niu, Hua Huang, Hua Zhang, Jia Pei, Jingmin Ou, Guangyin Yuan
Binary Zn-Cu alloy system is developed as potential biodegradable materials for cardiovascular implant application. The microstructure, tensile properties, in vitro corrosion behavior, cytotoxicity and antibacterial property of as-extruded Zn-xCu (x=1, 2, 3, and 4wt%) alloys are investigated systematically. It shows that as Cu content increases more CuZn5 phase precipitates. After extrusion, the CuZn5 phases are broken and the grains of Zn-xCu alloys are refined. Tensile test shows that Cu addition could significantly improve the mechanical properties of Zn-xCu alloys...
May 6, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28505593/foot-ankle-complex-injury-risk-curves-using-calcaneus-bone-mineral-density-data
#15
Narayan Yoganandan, Sajal Chirvi, Liming Voo, Nicholas DeVogel, Frank A Pintar, Anjishnu Banerjee
OBJECTIVE: Biomechanical data from post mortem human subject (PMHS) experiments are used to derive human injury probability curves and develop injury criteria. This process has been used in previous and current automotive crashworthiness studies, Federal safety standards, and dummy design and development. Human bone strength decreases as the individuals reach their elderly age. Injury risk curves using the primary predictor variable (e.g., force) should therefore account for such strength reduction when the test data are collected from PMHS specimens of different ages (age at the time of death)...
May 5, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28500999/effects-of-working-gas-pressure-on-zirconium-dioxide-thin-film-prepared-by-pulsed-plasma-deposition-roughness-wettability-friction-and-wear-characteristics
#16
M Berni, G Marchiori, A Gambardella, M Boi, M Bianchi, A Russo, A Visani, M Marcacci, P G Pavan, N F Lopomo
In joint arthroplasty one of the main issues related to the failure of prosthetic implants is due to the wear of the ultra-high molecular weight polyethylene (UHMWPE) component. Surface treatments and coatings have been recognized as enhancing methods, able to improve the tribological properties of the implants. Therefore, the main objective of this work was to investigate the possibility to fabricate yttria-stabilized zirconia (YSZ) coatings on a metal (AISI 316-L) substrate by means of Pulsed Electron Deposition, in order to improve the tribological behavior of the polymer-metal coupling, by reducing the initial wear of the UHMWPE component...
May 4, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28499165/preparing-diopside-nanoparticle-scaffolds-via-space-holder-method-simulation-of-the-compressive-strength-and-porosity
#17
Majid Abdellahi, Aliakbar Najafinezhad, Hamid Ghayour, Saeed Saber-Samandari, Amirsalar Khandan
In the present study, diopside nanopowders were prepared via mechanical milling with eggshell as the calcium source. The space holder method (compaction of ceramic powder and spacer) as one of the most important methods to produce ceramic/metal scaffolds was used to produce diopside scaffolds. For the first time, the effect of the spacer size on mechanical properties and porosity of the obtained scaffolds was experimentally discussed. According to the results obtained, the NaCl particles (as the spacer) with the size of 400-600µm maintained their original spherical shape during the compaction and sintering processes...
May 3, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28478349/influence-of-variations-in-stiffness-of-cervical-ligaments-on-c5-c6-segment
#18
Kuan Wang, Zhen Deng, Huihao Wang, Zhengyan Li, Hongsheng Zhan, Wenxin Niu
The ligaments of the cervical spine each play a critical role in maintaining stability. Large variations in the mechanical behavior of each ligament have been reported, but it remains unclear how these variations influence cervical biomechanics. The objective of this study was to investigate the mechanical response of the cervical spine to variations in the properties of each cervical ligament. A finite element model of the C5-C6 spine was constructed with the average material properties. The stiffness of each ligament was then changed in turn by increasing or decreasing it per its designated maximum or minimum stiffness...
May 3, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28525819/combination-of-flow-and-micropattern-alignment-affecting-flow-resistant-endothelial-cell-adhesion
#19
Xianghui Gong, Jie Yao, Hongping He, Xixi Zhao, Xiaoyi Liu, Feng Zhao, Yan Sun, Yubo Fan
Assuring cell adhesion to an underlying biomaterial surface under blood flow is vital to functional vascular grafts design. In vivo endothelial cells (ECs) are located under the microenvironment of both surface topography of the basement membrane and the mechanical loading resulting from blood flow. Both topographical and mechanical factors should thus be considered when designing vascular grafts to enhance the flow-resistant EC adhesion. This study aims to investigate effects of integrating biomaterial surface topography and flow on EC adhesion, which was a deficit in previous studies...
May 2, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28501000/combination-of-a-biodegradable-three-dimensional-3d-printed-cage-for-mechanical-support-and-nanofibrous-membranes-for-sustainable-release-of-antimicrobial-agents-for-treating-the-femoral-metaphyseal-comminuted-fracture
#20
Ying-Chao Chou, Demei Lee, Tzu-Min Chang, Yung-Heng Hsu, Yi-Hsun Yu, Err-Cheng Chan, Shih-Jung Liu
The aim of this study was to develop a biodegradable three-dimensional-printed polylactide (PLA) cage for promoting bony fixation and an antibiotics-embedded poly(d,l)-lactide-co-glycolide (PLGA) nanofibrous membrane for infectious prophylaxis during treating the comminuted metaphyseal fracture in a rabbit femoral model. The in vitro studies included measuring the mechanical properties of the 3D printed cage and determining release activities of vancomycin and ceftazidime from the nanofibers. The in vivo study included comparisons of rabbits of the femoral metaphyseal comminuted fracture treated with or without the combined biodegradable polymers...
May 2, 2017: Journal of the Mechanical Behavior of Biomedical Materials
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