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Journal of the Mechanical Behavior of Biomedical Materials

Daniel López-López, Romeu Araújo, Marta Elena Losa-Iglesias, Ricardo Becerro-de-Bengoa-Vallejo, António Santos, David Rodríguez-Sanz, César Calvo-Lobo
BACKGROUND: Customized foot orthoses (CFO) have been widely accepted to reduce the frequency of foot problems and postural disorders. The purpose of the research was to compare the influence of CFO utilization on the venous status among healthy females and males. METHODS: This was a quasi-experimental study (NCT03329430), which included 20 healthy subjects that completed all the stages of the process. The subjects showed an age mean of 20.00 ± 1.62 years and were recruited in a foot and ankle specialist center...
January 5, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Ryohei Hirose, Takaaki Nakaya, Yuji Naito, Tomo Daidoji, Hiroaki Yasuda, Hideyuki Konishi, Yoshito Itoh
BACKGROUND AND AIMS: Development of high-performance submucosal injection materials (SIMs) contribute to the advancement of endoscopic therapy for early-stage gastrointestinal neoplasms. This study aimed to develop a new ex vivo model that mimics the human gastrointestinal tract to evaluate the performance (the height and duration of the submucosal elevation) of various SIMs in detail. METHODS: A new ex vivo model that applies a constant tension to the tested specimen (the porcine gastric specimen) was developed...
January 5, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Weiping Ren, Wei Song, Sally Yurgelevic, David C Markel
We previously described the gelation mechanism of calcium polyphosphate (CPP) in the presence of water. In this study, we developed novel and injectable poly-dicalcium phosphate dihydrate (P-DCPD) forming cement by the reaction of acidic CPP gel with alkali tetracalcium phosphate (TTCP). The setting reaction mechanism of P-DCPD is due to the intermolecular interaction between CPP gel and TTCP that was supported by XRD, AFM, Raman spectra analysis and SEM. The setting mechanism of P-DCPD is completely different from the classical calcium phosphate cement (CPC) that achieves crystallization by monophosphates reaction...
January 4, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Paige V Tracy, Alan S Wineman, Francisco J Orejuela, Susan M Ramin, John O L DeLancey, James A Ashton-Miller
Remarkable changes must occur in the pelvic floor muscles and tissues comprising the birth canal to allow vaginal delivery. Despite these preparatory adaptations, approximately 13% of women who deliver vaginally for the first time (nulliparas) sustain tears near the origin of the pubovisceral muscle (PVM) which can result in pelvic organ prolapse later in life. To investigate why these tears occur, it is necessary to quantify the viscoelastic behavior of the term pregnant human birth canal. The goal of this study was to quantify the in vivo material properties of the human birth canal, in situ, during the first stage of labor and compare them to published animal data...
December 30, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Masayuki Kyomoto, Toru Moro, Shihori Yamane, Kenichi Watanabe, Masami Hashimoto, Sakae Tanaka, Kazuhiko Ishihara
Manipulating the surface and substrate of cross-linked polyethylene (CLPE) is an essential approach for obtaining life-long orthopedic bearings. We therefore proposed a bearing material comprised of an antioxidative substrate generated by vitamin E blending (HD-CLPE[VE]) with a poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC)-grafted surface, and investigated its wear resistance and oxidative stability under accelerated aging and load bearing conditions. Neither the hydration nor friction kinetics of the molecular network structure of the PMPC-grafted surface or the HD-CLPE(VE) substrate were influenced by accelerated aging but rather exhibited high stability even under high oxidation conditions...
December 30, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Arian Ehterami, Mansure Kazemi, Bahareh Nazari, Payam Saraeian, Mahmoud Azami
It is well established that the piezoelectric effect plays an important physiological role in bone growth, remodeling and fracture healing. Barium titanate, as a well-known piezoelectric ceramic, is especially an attractive material as a scaffold for bone tissue engineering applications. In this regard, we tried to fabricate a highly porous barium titanate based scaffolds by foam replication method and polarize them by applying an external electric field. In order to enhance the mechanical and biological properties, polarized/non-polarized scaffolds were coated with gelatin and nanostructured HA and characterized for their morphologies, porosities, piezoelectric and mechanical properties...
December 30, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Gurdev Singh, S Soundarapandian
The long standing need of the implant manufacturing industries is to fabricate multi-matrix, customized porous scaffold as cost-effectively. In recent years, freeze casting has shown greater opportunity in the fabrication of porous scaffolds (tricalcium phosphate, hydroxyapatite, bioglass, alumina, etc.) such as at ease and good control over pore size, porosity, a range of materials and economic feasibility. In particular, tricalcium phosphate (TCP) has proved as it possesses good biocompatible (osteoinduction, osteoconduction, etc...
December 30, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Chet C Xu, Roger W Chan, Han Sun, Xiaowei Zhan
No abstract text is available yet for this article.
December 29, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Hyung-In Yoon, Min-Jeong Jeon, Hye-Lee Kim, Do-Gyoon Kim, Jung-Suk Han
The aim of the study was to evaluate the spatial variations in the biomechanical properties of the bone around the implants retrieved from human subjects due to fixture head fracture after almost 20 years of loading. The implant-in-bone specimens were prepared for the histomorphometry and nanoindentation test to measure the bone-to-implant contact ratio (BIC ratio) and elastic modulus (E) of peri-implant bone. The indentations were performed in the up, center, down, and away regions of the bone tissues within all the thread spaces...
December 28, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Pietro Ridone, Stephan L Grage, Amrutha Patkunarajah, Andrew R Battle, Anne S Ulrich, Boris Martinac
The level of fatty acid saturation in phospholipids is a crucial determinant of the biophysical properties of the lipid bilayer. Integral membrane proteins are sensitive to changes of their bilayer environment such that their activities and localization can be profoundly affected. When incorporated into phospholipids of mammalian cells, poly-unsaturated fatty acids (PUFAs) determine the mechanical properties of the bilayer thereby affecting several membrane-associated functions such as endo- and exo-cytosis and ion channel/membrane receptor signalling cascades...
December 28, 2017: Journal of the Mechanical Behavior of Biomedical Materials
J Ortún-Terrazas, J Cegoñino, U Santana-Penín, U Santana-Mora, A Pérez Del Palomar
The periodontal ligament (PDL) is a porous and fibrous soft tissue situated around the tooth, which plays a key role in the transmission of loads from the tooth to the alveolar bone of the mandible. Although several studies have tried to characterize its mechanical properties, the behaviour of this tissue is not clear yet. In this study, a new simulation methodology based on a material model which considers the contribution of porous and fibrous structure with different material model formulations depending on the effort direction is proposed...
December 28, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Lucien Diotalevi, Yvan Petit, Vladimir Brailovski, Sylvain Nichols, Emma Marchionatti, Éric Wagnac
Mechanical properties of the Cranial Cruciate Ligament (CrCL) in adult cattle are not well documented and protocols used in the literature focus on testing a full femur-CrCL-tibia complex rather than an isolated CrCL. The aim of this study was to assess a wider range of tensile properties of the CrCL along its anatomic axis with experimental measurements of the global elongation, displacement and strain fields, in order to provide guidelines for the design of CrCL prosthetic surrogates. Fourteen bovine CrCL were harvested from seven mature cows (5...
December 26, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Dries De Kegel, Julie Vastmans, Heleen Fehervary, Bart Depreitere, Jos Vander Sloten, Nele Famaey
A reliable computational model of the human head is necessary for better understanding of the physical mechanisms of traumatic brain injury (TBI), car-crash investigation, development of protective head gear and advancement of dural replacement materials. The performance and biofidelity of these models depend largely on the material description of the different structures present in the head. One of these structures is the dura mater, the protective layer around the brain. We tested five human dura mater specimens, with samples at different locations, using planar biaxial tests...
December 26, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Justin J Morton, Matthew Bennison, W Brent Lievers, Stephen D Waldman, A Keith Pilkey
Skeletal fractures, including those resulting from osteoporosis, result in significant healthcare and societal costs on an annual basis. Therefore, it is important to understand the mechanisms by which these fractures occur. Incremental compression testing combined with micro-CT imaging has been used to visualize the progression of failure in trabecular bone samples; however, these studies have ignored the potential contributions of the cortical shell. In the current study, incremental compression testing with simultaneous micro-CT imaging was performed on rat vertebrae from multiple disease states (healthy control, osteoporotic, osteoporotic + treatment)...
December 26, 2017: Journal of the Mechanical Behavior of Biomedical Materials
K Narooei, M Arman
In this research, the exponential stretched based hyperelastic strain energy was generalized to the hyper-viscoelastic model using the heredity integral of deformation history to take into account the strain rate effects on the mechanical behavior of materials. The heredity integral was approximated by the approach of Goh et al. to determine the model parameters and the same estimation was used for constitutive modeling. To present the ability of the proposed hyper-viscoelastic model, the stress-strain response of the thermoplastic elastomer gel tissue at different strain rates from 0...
December 23, 2017: Journal of the Mechanical Behavior of Biomedical Materials
J A Sanz-Herrera, E Reina-Romo, A R Boccaccini
Magnesium-based biomedical implants offer many advantages versus traditional ones although some challenges are still present. In this context, mathematical modeling and computational simulation may be a useful and complementary tool to evaluate in silico the performance of magnesium biomaterials under different conditions. In this paper, a phenomenologically-based model to simulate magnesium corrosion is developed. The model describes the physico-chemical interactions and evolution of species present in this phenomenon...
December 21, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Michael Di Giuseppe, Nicholas Law, Braeden Webb, Ryley A Macrae, Lawrence J Liew, Timothy B Sercombe, Rodney J Dilley, Barry J Doyle
Hydrogels comprised of alginate and gelatin have demonstrated potential as biomaterials in three dimensional (3D) bioprinting applications. However, as with all hydrogel-based biomaterials used in extrusion-based bioprinting, many parameters influence their performance and there is limited data characterising the behaviour of alginate-gelatin (Alg-Gel) hydrogels. Here we investigated nine Alg-Gel blends by varying the individual constituent concentrations. We tested samples for printability and print accuracy, compressive behaviour and change over time, and viability of encapsulated mesenchymal stem cells in bioprinted constructs...
December 21, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Peng-Fei Yang, Xiao-Tong Nie, Dong-Dong Zhao, Zhe Wang, Li Ren, Hui-Yun Xu, Joern Rittweger, Peng Shang
The mechanical properties of the bone play a decisive role in the resistance of the bone to fracture. Clinically, the quantity of the bone in the mineral phase has been considered as the gold-standard indicator for the risk of bone fracture. However, the bone is a complex tissue with a hierarchical-structure consisting of organic matrix, mineral hydroxyapatite, and water. Collagen comprises up to 90% of the organic matrix in the bone, and is vital for its mechanical behavior. To date, the morphological and mechanical responses of collagen fibrils in the bone matrix have been largely overlooked...
December 16, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Min-Jung Kim, Hye-Jeong Shin, Hyung-Il Kim, Yong Hoon Kwon, Hyo-Joung Seol
This study examined the effect of ice-quenching after oxidation treatment on hardness change of a Pd-Cu-Ga-Zn metal-ceramic alloy during porcelain firing simulation. Although not statistically significant, the alloy was softened slightly during porcelain firing simulation with conventional slow cooling rate. On the other hand, the hardness increased significantly by ice-quenching instead of the slow cooling after oxidation (p<0.001). The gap in the final hardness depending on ice-quenching occurred in the matrix and plate-like precipitates but not in the particle-like structure without plate-like precipitates (p<0...
December 15, 2017: Journal of the Mechanical Behavior of Biomedical Materials
Hui Ying Ang, Jingni Chan, Daniel Toong, Subbu S Venkatraman, Sing Joo Chia, Ying Ying Huang
Blending polymers with complementary properties capitalizes on the inherent advantages of both components, making it possible to tailor the behaviour of the resultant material. A polymer blend consisting of an elastomer and thermoplastic can help to improve the mechanical integrity of the system without compromising on its processibility. A series of blends of biodegradable Poly(L-lactide-co-ɛ-caprolactone) (PLC) and Poly-(l,l-lactide-co-glycolic acid) (PLLGA), and PLC with Poly-(d,l-lactide-co-glycolic acid) (PDLLGA) were evaluated as a potential material for a biodegradable vesicourethral connector device...
December 15, 2017: Journal of the Mechanical Behavior of Biomedical Materials
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