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Journal of the Mechanical Behavior of Biomedical Materials

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https://www.readbyqxmd.com/read/29149656/location-specific-mechanical-response-and-morphology-of-facial-soft-tissues
#1
Marco Pensalfini, Johannes Weickenmeier, Marga Rominger, Roberto Santoprete, Oliver Distler, Edoardo Mazza
The facial tissue of 9 healthy volunteers (m/f; age: 23-60y) is characterized at three different locations using a procedure combining suction measurements and 18MHz ultrasound imaging. The time-dependent and multilayered nature of skin is accounted for by adopting multiple loading protocols which differ with respect to suction probe opening size and rate of tissue deformation. Over 700 suction measurements were conducted and analyzed according to location-specific mechanical and morphological characteristics...
November 14, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29145010/the-use-of-hardened-bone-cement-as-an-impaction-grafting-extender-for-revision-hip-arthroplasty
#2
Mark Ruddy, David P FitzPatrick, Kenneth T Stanton
Impaction bone grafting is a method of restoring bone stock to patients who have suffered significant bone loss due to revision total hip surgery. The procedure requires morsellised cancellous bone (MCB) to be impacted into the site of bone loss in order to stabilise the prosthesis with the aim of long term resorption and reintegration of the impacted bone graft. Due to financial cost and the potential to transmit disease, the use of supplementary material, known as an extender, is frequently used to increase the graft material volume...
November 13, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29136577/atomic-force-microscopy-study-revealed-velocity-dependence-and-nonlinearity-of-nanoscale-poroelasticity-of-eukaryotic-cells
#3
Keyvan Mollaeian, Yi Liu, Siyu Bi, Juan Ren
Intracellular network deformation of the cell plays an important role in cellular shape formation. Recent studies suggest that cell reshaping and deformation due to external forces involve cellular volume, pore size, elasticity, and intracellular filaments polymerization degree change. This cell behavior can be described by poroelastic models due to the porous structure of the cytoplasm. In this study, the nanoscale poroelasticity of human mammary basal/claudin low carcinoma cell (MDA-MB-231) was investigated using indentation-based atomic force microscopy...
November 11, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29145011/preparation-of-morselised-bone-for-impaction-grafting-using-a-blender-method
#4
Mark Ruddy, David P FitzPatrick, Kenneth T Stanton
Impaction bone grafting is a method of restoring bone stock to patients suffering significant bone loss due to revision total hip surgery. The procedure requires morselised bone (MB) to be impacted into the site of bone loss in order to stabilise the prosthesis with the aim of the long term resorption and reintegration of the impacted bone graft. Currently, the method for producing MB requires the use of expensive surgical bone mills or manually-intensive rongeurs that can produce a limited variety of particle sizes and may have a low throughput...
November 9, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29132101/contributions-of-the-layer-topology-and-mineral-content-to-the-elastic-modulus-and-strength-of-fish-scales
#5
Sandra Murcia, Yuri Miyamoto, Megha Pratap Varma, Alexander Ossa, Dwayne Arola
Fish scales are an interesting natural structural material and their functionality requires both flexibility and toughness. Our previous studies identified that there are spatial variations in the elastic properties of fish scales corresponding to the anatomical regions, and that they appear to be attributed to changes in the microstructure. In the present study, a model is proposed that describes the elastic behavior of elasmoid fish scales in terms of the relative contributions of the limiting layer and both the internal and external elasmodine...
November 7, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29128693/effect-of-adding-support-structures-for-overhanging-part-on-fatigue-strength-in-selective-laser-melting
#6
Yuka Kajima, Atsushi Takaichi, Takayuki Nakamoto, Takahiro Kimura, Nuttaphon Kittikundecha, Yusuke Tsutsumi, Naoyuki Nomura, Akira Kawasaki, Hidekazu Takahashi, Takao Hanawa, Noriyuki Wakabayashi
Selective laser melting (SLM) technology was recently introduced to fabricate dental prostheses. However, the fatigue strength of clasps in removable partial dentures prepared by SLM still requires improvement. In this study, we attempted to improve the fatigue strength of clasps by adding support structures for overhanging parts, which can generally be manufactured at an angle to be self-supporting. The results show that the fatigue strength of the supported specimens was more than twice that of unsupported specimens...
November 6, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29132097/the-development-of-a-new-artificial-model-of-a-finger-for-assessing-transmitted-vibrations
#7
Almaky Almagirby, Jem A Rongong, Matt J Carré
Prolonged exposure of the hand to tool-induced vibrations is associated with the occurrence of conditions such as vibration white finger. This study involves the development of a new artificial model that approximates both loading and vibration behaviour of the human finger. The layered system uses polypropylene "bones", encased in a cylinder of low modulus, room-temperature curing silicone gel (to replicate subcutaneous tissues), with an outer layer of latex (to replicate the dermis and epidermis). A protocol for manufacture was developed and dynamic mechanical analysis was carried out on a range of gels in order to choose a range close to the mechanical properties of the human finger...
November 4, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29132098/understanding-the-mechanism-for-the-mechanical-property-degradation-of-a-lithium-disilicate-glass-ceramic-by-annealing
#8
D Li, X C Li, Z Z Zhang, S F Zhang, L He
Post-crystallization annealing above the Tg was applied to a lithium disilicate glass-ceramic with microstructure consisting of glassy matrix and rod-like lithium disilicate crystals, effect of the annealing on the mechanical behavior was investigated. Flexural strength and VIF toughness of the glass-ceramic unexpectedly decreased after the annealing. The mechanical behavior variation was understood based on residual micro-stress analysis. Coefficient of thermal expansion for the glassy matrix presented a tendency to increase after the annealing, which would enlarge the thermal expansion mismatch between the glassy matrix and the lithium disilicate crystals...
November 3, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29101896/a-simplified-application-app-for-the-parametric-design-of-screw-plate-fixation-of-bone-fractures
#9
Chen-Yuan Chung
Screw and plate fixation is commonly used to treat bone fractures. A prototype application (APP) for presurgical simulation was developed and validated by comparing it with current analytical approach and other models. In this APP, alternative plate designs and materials to limit the effects of stress shielding could be tested. In addition, the number and position of screws and the gap between bone and plate that achieved acceptable stability were predicted. The fixation stability providing a situation of interfragmentary strain between 2% and 10% is necessary for callus formation...
November 1, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29136578/deformation-mechanisms-of-prototype-composite-braided-stent-grafts-in-bending-fatigue-for-peripheral-artery-application
#10
Wen Xue, Jing Gao, Jing Lin, Fujun Wang, Guoping Guan, Lu Wang
Stent-grafts in peripheral arteries suffer from complex cyclic loadings in vivo, including pulsatile, axial bending and torsion. Normal fatigue durability evaluation technologies, however, are majorly based on pulsation and thus are short of accuracy under the complicated stress conditions experienced physiologically. While there is a little research focused on the cyclic fatigue of stent-grafts in bending, it remains an almost total lack of deformation or fatigue mechanisms. In this work, composite braided stent-grafts incorporating Nitinol (NiTi) yarns and polyethylene terephthalate (PET) multifilament yarns were cycled in bending by the self-developed testing system to investigate their deformation behaviors...
October 31, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29132100/comparison-of-microsphere-penetration-with-lc-bead-lumi%C3%A2-versus-other-commercial-microspheres
#11
Marcus Caine, Xunli Zhang, Martyn Hill, Wei Guo, Koorosh Ashrafi, Zainab Bascal, Hugh Kilpatrick, Anthony Dunn, David Grey, Rosemary Bushby, Andrew Bushby, Sean L Willis, Matthew R Dreher, Andrew L Lewis
The purpose of this study was to evaluate LC Bead LUMI™ (40-90µm and 70-150µm) in order to determine if their increased resistance to compression influences microsphere penetration and distribution compared to more compressible commercial microspheres. LC Bead LUMI™ 40-90µm and 70-150µm, LC BeadM1(®) 70-150µm, Embozene™ 40µm and Embozene™ 100µm size and distributions were measured using optical microscopy. Penetration in vitro was evaluated using an established 'plate model', consisting of a calibrated tapered gap between a glass plate and plastic housing to allow visual observation of microsphere penetration depth...
October 31, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29128694/poly-l-lactide-nanocomposites-containing-poly-d-lactide-grafted-nanohydroxyapatite-with-improved-interfacial-adhesion-via-stereocomplexation
#12
Guangmei Huang, Zhiyun Du, Zuoying Yuan, Lihua Gu, Qing Cai, Xiaoping Yang
Biodegradable organic-inorganic composites composed of polylactide (PLA) and hydroxyapatite (HA) are important bone repairing materials, while the dispersibility of nanoscaled HA in PLA and the interfacial adhesion between HA and PLA remained unsatisfactory. In this study, poly(D-lactide) (PDLA) oligomers with different molecular weights were grafted onto HA nanorods (HA-PDLA), and the HA-PDLA hybrids were mixed with poly(L-lactide) (PLLA). Dispersibility of HA-PDLA hybrids in PLLA matrix was investigated, and the formation of PDLA/PLLA stereocomplex at the interface of HA-PDLA and PLLA was studied by characterizations including crystallization, mechanical and thermal properties, taking PLLA grafted HA (HA-PLLA) and unmodified HA as comparisons...
October 31, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29102892/multi-tubule-conduit-filler-constructs-loaded-with-gradient-distributed-growth-factors-for-neural-tissue-engineering-applications
#13
Hua Wu, Qing Fang, Jiaoyan Liu, Xiaofeng Yu, Yigui Xu, Ying Wan, Bo Xiao
Chitosan/silk fibroin/glycerophosphate gels were loaded with nerve growth factor (NGF) and further processed into multi-tubule fillers. NGF was loaded into the fillers in such a way so that a NGF gradient was established longitudinally along the filler length. A type of poly(lactide-co-glycolide)(PLGA)/chitosan(CH) porous conduit was fabricated using a pre-crosslinking method. The filler was fully filled into the lumen of conduits to build multi-tubule conduit-filler constructs that are intended for long-gap peripheral nerve repair...
October 27, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29100204/finite-element-wear-prediction-using-adaptive-meshing-at-the-modular-taper-interface-of-hip-implants
#14
Thom Bitter, Imran Khan, Tim Marriott, Elaine Lovelady, Nico Verdonschot, Dennis Janssen
The use of modular components in total hip arthroplasty introduced an additional interface with the potential for fretting and corrosion to occur. Fretting and corrosion at this interface have been reported as a potential cause of early failure of the implant system. Using finite element (FE) analyses the mechanics at the taper junction can be studied. However, most FE studies are based on a single load condition and do not take geometry changes over time into account. Therefore, in this study an FE routine was developed, in which adaptations to the implant geometry are made to account for material removal during the fretting process...
October 27, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29132099/tribological-properties-of-pva-pvp-blend-hydrogels-against-articular-cartilage
#15
Yusuf Kanca, Piers Milner, Daniele Dini, Andrew A Amis
This research investigated in-vitro tribological performance of the articulation of cartilage-on- polyvinyl alcohol (PVA) and polyvinyl pyrrolidone (PVP) blend hydrogels using a custom-designed multi-directional wear rig. The hydrogels were prepared by repeated freezing-thawing cycles at different concentrations and PVA to PVP fractions at a given concentration. PVA/PVP blend hydrogels showed low coefficient of friction (COF) values (between 0.12 ± 0.01 and 0.14 ± 0.02) which were closer to the cartilage-on-cartilage articulation (0...
October 25, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29102893/effect-of-mechanical-stress-on-the-raman-and-infrared-bands-of-hydroxylapatite-a-quantum-mechanical-first-principle-investigation
#16
Gianfranco Ulian, Giovanni Valdrè
The calcium apatite minerals are among the most studied in the biomaterial field because of their similarity with the mineral phase of bone tissues, which is mainly the hexagonal polymorph of hydroxylapatite. Given the growing interest both in the microscopic processes governing the behaviour of these natural biomaterials and in recent experimental methods to investigate the Raman response of hydroxylapatite upon mechanical loading, we report in the present work a detailed quantum mechanical analysis by DFT/B3LYP-D* approach on the Raman and infrared responses of hydroxylapatite upon deformation of its unit cell...
October 25, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29096123/in-vitro-validation-of-a-novel-mechanical-model-for-testing-the-anchorage-capacity-of-pedicle-screws-using-physiological-load-application
#17
Christian Liebsch, Julia Zimmermann, Nicolas Graf, Christoph Schilling, Hans-Joachim Wilke, Annette Kienle
Biomechanical in vitro tests analysing screw loosening often include high standard deviations caused by high variabilities in bone mineral density and pedicle geometry, whereas standardized mechanical models made of PU foam often do not integrate anatomical or physiological boundary conditions. The purpose of this study was to develop a most realistic mechanical model for the standardized and reproducible testing of pedicle screws regarding the resistance against screw loosening and the holding force as well as to validate this model by in vitro experiments...
October 25, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29100203/elastic-behavior-of-brain-simulants-in-comparison-to-porcine-brain-at-different-loading-velocities
#18
Lisa Falland-Cheung, Mario Scholze, Niels Hammer, J Neil Waddell, Darryl C Tong, Paul A Brunton
Blunt force impacts to the head and the resulting internal force transmission to the brain and other cranial tissue are difficult to measure. To model blunt force impact scenarios, the compressive properties resembling tissue elasticity are of importance. Therefore, this study investigated and compared the elastic behavior of gelatin, alginate, agar/glycerol and agar/glycerol/water simulant materials to that of porcine brain in a fresh and unfixed condition. Specimens, 10 × 10 × 10mm(3), were fabricated and tested at 22°C, apart from gelatin which was conditioned to 4°C prior to testing...
October 24, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29096125/biaxial-mechanical-behavior-of-bovine-saphenous-venous-valve-leaflets
#19
Jiaqi Lu, Hsiao-Ying Shadow Huang
Chronic venous disease is caused by chronic venous insufficiency (CVI), which results in significant symptoms such as venous ulcers, ankle eczema, leg swelling, etc. Venous valve incompetence is a major cause of CVI. When the valves of veins in the leg become incompetent (i.e., do not close properly), blood is able to flow backwards (i.e., reflux), which results in blood pooling in the lower extremities, distal venous hypertension, and CVI. Current clinical therapies, such as surgical venous valve reconstruction and bioprosthetic venous valve replacement, are highly invasive and only moderately successful...
October 24, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29101897/estimation-of-in-vivo-mechanical-properties-of-the-aortic-wall-a-multi-resolution-direct-search-approach
#20
Minliang Liu, Liang Liang, Wei Sun
The patient-specific biomechanical analysis of the aorta requires in vivo mechanical properties of individual patients. Existing approaches for estimating in vivo material properties often demand high computational cost and mesh correspondence of the aortic wall between different cardiac phases. In this paper, we propose a novel multi-resolution direct search (MRDS) approach for estimation of the nonlinear, anisotropic constitutive parameters of the aortic wall. Based on the finite element (FE) updating scheme, the MRDS approach consists of the following three steps: (1) representing constitutive parameters with multiple resolutions using principal component analysis (PCA), (2) building links between the discretized PCA spaces at different resolutions, and (3) searching the PCA spaces in a 'coarse to fine' fashion following the links...
October 20, 2017: Journal of the Mechanical Behavior of Biomedical Materials
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