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Journal of the Mechanical Behavior of Biomedical Materials

Lianxi Chen, Yuanhong Bin, Wenqi Zou, Xiaojian Wang, Wei Li
In the present work, new magnesium (Mg) alloys (Mg-4Zn-0.6Zr-xSr, x=0, 0.4, 0.8, 1.2, 1.6wt%; ZK40xSr) were prepared and studied as potential biodegradable materials. The influence of strontium (Sr) addition on the properties of the new Mg alloys was investigated, which included microstructure, corrosion degradation, and the stress corrosion cracking (SCC) susceptibility. The average grain size of the ZK40Sr was approximately 100µm, which was significantly smaller than that of ZK40 alloy without Sr (402.3±40...
November 18, 2016: Journal of the Mechanical Behavior of Biomedical Materials
A Nawaz, W G Mao, C Lu, Y G Shen
The nanoscale elastic-plastic response of single crystal 4H-SiC has been investigated by nanoindentationwith a Berkovich tip. The hardness (H) and elastic modulus (E) determined in the load-independent region were 36±2GPa and 413±8GPa, respectively. The indentation size effect (ISE) of hardness within an indentation depth of 60nm was systematically analyzed by the Nix-Gao model. Pop-in events occurring at a depth of ~23nm with indentation loads of 0.60-0.65mN were confirmed to indicate the elastic-plastic transition of the crystal, on the basis of the Hertzian contact theory and Johnson's cavity model...
November 17, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Masoud Sarraf, Bushroa Abdul Razak, Bahman Nasiri-Tabrizi, Ali Dabbagh, Noor Hayaty Abu Kasim, Wan Jefrey Basirun, Eshamsul Bin Sulaiman
Tantalum pentoxide nanotubes (Ta2O5 NTs) can dramatically raise the biological functions of different kinds of cells, thus have promising applications in biomedical fields. In this study, Ta2O5 NTs were prepared on biomedical grade Ti-6Al-4V alloy (Ti64) via physical vapor deposition (PVD) and a successive two-step anodization in H2SO4: HF (99:1)+5% EG electrolyte at a constant potential of 15V. To improve the adhesion of nanotubular array coating on Ti64, heat treatment was carried out at 450°C for 1h under atmospheric pressure with a heating/cooling rate of 1°Cmin(-)(1)...
November 16, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Haruki Imai, Yoji Tanaka, Naoyuki Nomura, Hisashi Doi, Yusuke Tsutsumi, Takashi Ono, Takao Hanawa
Zr-Ag composites were fabricated to decrease the magnetic susceptibility by compensating for the magnetic susceptibility of their components. The Zr-Ag composites with a different Zr-Ag ratio were swaged, and their magnetic susceptibility, artifact volume, and mechanical properties were evaluated by magnetic balance, three-dimensional (3-D) artifact rendering, and a tensile test, respectively. These properties were correlated with the volume fraction of Ag using the linear rule of mixture. We successfully obtained the swaged Zr-Ag composites up to the reduction ratio of 96% for Zr-4, 16, 36, 64Ag and 86% for Zr-81Ag...
November 12, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Michał Sobota, Sebastian Jurczyk, Michał Kwiecień, Anna Smola-Dmochowska, Marta Musioł, Marian Domański, Henryk Janeczek, Michał Kawalec, Piotr Kurcok
Materials with shape memory effect (SME) have already been widely used in the medical field. The interesting part of this group is represented by double function materials. The bioresorption and SME ability are common in polyesters implants. The first information about vascular stent made of bioresorbable polyester with SME was published in 2000. However, there are not many investigations about SME control of elements in the aspect of material processing. In the present work, the ability to control the shape memory (SM) of bioresorbable and semicrystalline poly(L-lactide) (PLLA) is investigated...
November 12, 2016: Journal of the Mechanical Behavior of Biomedical Materials
R Simón-Allué, B Calvo, A A Oberai, P E Barbone
The aim of this study is to characterize the passive mechanical behaviour of abdominal wall in vivo in an animal model using only external cameras and numerical analysis. The main objective lies in defining a methodology that provides in vivo information of a specific patient without altering mechanical properties. It is demonstrated in the mechanical study of abdomen for hernia purposes. Mechanical tests consisted on pneumoperitoneum tests performed on New Zealand rabbits, where inner pressure was varied from 0mmHg to 12mmHg...
November 12, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Xuelei Zhang, Zhurong Tang, Yong Zhou, Xuening Chen, Xiangdong Zhu, Yujiang Fan, Yu Zhang, Xiao Yang, Chong-Qi Tu, Xingdong Zhang
Osteosarcoma is the most common primary malignancy of bone. However, the potential variation it brings to the adjacent undamaged bone tissue is seldom investigated. In this study, we conducted a multi-level comparison of human femoral cortical bone quality in healthy cadavers (aged 42±11 years) and in resected safe margin of osteosarcoma patients (aged 49±15 years). The objective of this study was to document the changes with exposure to osteosarcoma condition in bone mechanical strength, structural morphology and elementary composition, evaluated by static and dynamic mechanical analysis (DMA), scanning electron microscopy (SEM) imaging, X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FTIR)...
November 12, 2016: Journal of the Mechanical Behavior of Biomedical Materials
M D Peng, J Q Wei, Y N Wang, Q Li
The aim of the present study was to investigate the effects of low-temperature aging on the micro-mechanical and micro-structural properties of zirconia-porcelain interface. In total, thirty-three Y-TZP zirconia blocks were fabricated by using CAD/CAM technology, veneered with porcelains. Specimens were submitted to low-temperature aging in an autoclave at 134°C, additional 0.2MPa pressure for 0h, 5h, or 10h. Flexural strength was obtained by using three-point bending test. Micro-mechanical properties (nano-hardness (H) and reduced modulus (Er)) were investigated by nanoindentation tests...
November 11, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Priyanka Srinivasan, Mark A Miller, Nico Verdonschot, Kenneth A Mann, Dennis Janssen
Aseptic loosening of the tibial component remains the leading cause for revision surgery in total knee arthroplasty (TKA). Understanding the mechanisms leading to loss of fixation can offer insight into preventative measures to ensure a longer survival rate. In cemented TKA, loosening occurs at the cement-trabecular interface probably due to a stress-shielding effect of the stiffer implant material in comparison with bone. Using finite element models of lab-prepared tibial cement-trabeculae interface specimens (n=4) based on micro-CT images, this study aims to investigate the micromechanics of the interlock between cement and trabecular bone...
November 10, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Zhaolong Han, Jiasong Li, Manmohan Singh, Chen Wu, Chih-Hao Liu, Raksha Raghunathan, Salavat R Aglyamov, Srilatha Vantipalli, Michael D Twa, Kirill V Larin
The biomechanical properties of the cornea play a critical role in forming vision. Diseases such as keratoconus can structurally degenerate the cornea causing a pathological loss in visual acuity. UV-A/riboflavin corneal collagen crosslinking (CXL) is a clinically available treatment to stiffen the cornea and restore its healthy shape and function. However, current CXL techniques do not account for pre-existing biomechanical properties of the cornea nor the effects of the CXL treatment itself. In addition to the inherent corneal structure, the intraocular pressure (IOP) can also dramatically affect the measured biomechanical properties of the cornea...
November 5, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Noélia M S Leal, Juscelino L Silva, Maria Ivone M Benigno, Eliane A Bemerguy, Josete B C Meira, Rafael Y Ballester
OBJECTIVE: To introduce an experimental non-carious cervical lesion (NCCL) model for studying the influence of presence and type of stress (tension or compression) on acid effects involved in NCCL formation on the enamel near the cement-enamel junction (CEJ). METHODS: 108 bovine incisors were cut into 18 × 3×3 mm(3) beams, with a notch in the cervical region to generate a standardized area of stress concentration. Half of the specimens were immersed in distilled water and the other half in acetic acid solution (pH 4...
November 4, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Scott T Lovald, Andrew Rau, Steven Nissman, Nicoli Ames, John McNulty, Jorge A Ochoa, Michael Baldwinson
Penetration injuries of the eye are among the most frequent causes of permanent visual impairment resulting from trauma. The purpose of this study was to determine the peak strain at which rupture occurs in the cornea due to a penetrating object. Probes of varying diameters (1.0, 1.5, and 2.0mm) were pressed into the apex of the cornea of 36 human cadaveric eye specimens until perforation or rupture of the specimen at the cornea, limbus, or sclera occurred. An axisymmetric finite element model of the human globe was created to replicate the experimental set-up...
November 3, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Mohammad Mirjavan, Azita Asayesh, Ali Asghar Asgharian Jeddi
Surgical mesh is being used for healing hernia, pelvic organ prolapse, skull injuries and urinary incontinence. In this research the effect of fabric structure on the mechanical properties of warp knitted surgical meshes in comparison to abdominal fascia has been investigated. For this purpose, warp knitted surgical mesh with five different structures (Tricot, Pin-hole-net, quasi-Sandfly, Sandfly and quasi-Marquissite) were produced using polypropylene monofilament. Thereafter, their mechanical properties such as uniaxial tensile behavior in various directions (wale-wise (90°), course-wise (0°) and diagonal (45°)), bending resistance and crease recovery were analyzed...
November 2, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Vee San Cheong, Angelo Karunaratne, Andrew A Amis, Anthony M J Bull
Radiological features alone do not allow the discrimination between accidental paediatric long bone fractures or those sustained by child abuse. Therefore, there is a clinical need to elucidate the mechanisms behind each fracture to provide a forensic biomechanical tool for the vulnerable child. Four-point bending and torsional loading tests were conducted at more than one strain rate for the first time on immature bone, using a specimen-specific alignment system, to characterise structural behaviour at para-physiological strain rates...
November 2, 2016: Journal of the Mechanical Behavior of Biomedical Materials
R B Giesberts, E E G Hekman, P G M Maathuis, G J Verkerke
The Ponseti method is the accepted treatment of idiopathic clubfoot. Although the method of manipulating the baby feet is described in great detail, current study aimed to investigate the magnitude and course of the applied forces in order to optimise the treatment of clubfoot. An instrumented clubfoot model was constructed with force sensors on the location of the first metatarsal (FM) and the talar neck (TN) and treated with the Ponseti method by 17 practitioners. Applied forces on FM and TN were measured during manipulation (4...
November 2, 2016: Journal of the Mechanical Behavior of Biomedical Materials
X X Sun, Z L Zhou, C H Man, A Y H Leung, A H W Ngan
A drug-free procedure for killing malignant cells in a cell-type specific manner would represent a significant breakthrough for leukemia treatment. Here, we show that mechanically vibrating a cell in a specific oscillation condition can significantly promote necrosis. Specifically, oscillating the cell by a low-power laser trap at specific frequencies of a few Hz was found to result in increased death rate of 50% or above in different types of myelogenous leukemia cells, while normal leukocytes showed very little response to similar laser manipulations...
November 1, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Melika Mohammadkhah, Ciaran K Simms, Paula Murphy
Detection and visualisation of Collagen structure are important to understand the relationship between mechanical behaviour and microstructure in skeletal muscle since Collagen is the main structural protein in animal connective tissues, and is primarily responsible for their passive load-bearing properties. In the current study, the direct detection and visualization of Collagen using fluorescently tagged CNA35 binding protein (fused to EGFP or tdTomato) is reported for the first time on fixed skeletal muscle tissue...
November 1, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Steven Leuridan, Quentin Goossens, Leonard Pastrav, Jorg Roosen, Michiel Mulier, Kathleen Denis, Wim Desmet, Jos Vander Sloten
Replicate composite bones are used extensively for in vitro testing of new orthopedic devices. Contrary to tests with cadaveric bone material, which inherently exhibits large variability, they offer a standardized alternative with limited variability. Accurate knowledge of the composite's material properties is important when interpreting in vitro test results and when using them in FE models of biomechanical constructs. The cortical bone analogue material properties of three different fourth-generation composite bone models were determined by updating FE bone models using experimental and numerical modal analyses results...
October 29, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Ourania-Menti Goudouri, Eleana Kontonasaki, Lambrini Papadopoulou, Marianthi Manda, Panagiotis Kavouras, Konstantinos S Triantafyllidis, Maria Stefanidou, Petros Koidis, Konstantinos M Paraskevopoulos
The aim of this study was the evaluation of the textural characteristics of an experimental sol-gel derived feldspathic dental ceramic, which has already been proven bioactive and the investigation of its flexural strength through Weibull Statistical Analysis. The null hypothesis was that the flexural strength of the experimental and the commercial dental ceramic would be of the same order, resulting in a dental ceramic with apatite forming ability and adequate mechanical integrity. Although the flexural strength of the experimental ceramics was not statistically significant different compared to the commercial one, the amount of blind pores due to processing was greater...
October 28, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Laura C Mozdzen, Alan Vucetic, Brendan A C Harley
The tendon-to-bone junction is a highly specialized tissue which dissipates stress concentrations between mechanically dissimilar tendon and bone. Upon injury, the local heterogeneities across this insertion are not regenerated, leading to poor functional outcomes such as formation of scar tissue at the insertion and re-failure rates exceeding 90%. Although current tissue engineering methods are moving towards the development of spatially-graded biomaterials to begin to address these injuries, significant opportunities remain to engineer the often complex local mechanical behavior of such biomaterials to enhance their bioactivity...
October 27, 2016: Journal of the Mechanical Behavior of Biomedical Materials
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