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Clinical Ophthalmology

Mark Packer, Jon I Williams, Gregg Feinerman, Richard S Hope
Purpose: Glistening formation in the intraocular lens (IOL) optic has the potential to impact quality of vision. The enVista One-Piece Hydrophobic Acrylic Spherical IOL Model MX60 (MX60 IOL) is currently the only US Food and Drug Administration-approved IOL with a label of "no glistenings". The purpose of this prospective, multicenter, partially randomized, partially controlled, double-masked, pivotal study was to evaluate the safety and effectiveness of the enVista One-Piece Hydrophobic Acrylic MX60T Toric IOL (enVista MX60T Toric IOL)...
2018: Clinical Ophthalmology
Manoj Motwani
Purpose: This pilot study was conducted to test the hypothesis that WaveLight® Contoura and wavefront-optimized (WFO) hyperopic treatment can be used together for hyperopia/hyperopic astigmatism to create more uniform corneas. Materials and methods: A retrospective analysis was conducted in 35 consecutive hyperopic/hyperopic astigmatism eyes of 22 patients treated via LASIK on the Wavelight® EX500. Higher order aberrations and astigmatism were removed using Contoura with the Layer Yolked Reduction of Astigmatism (LYRA) Protocol, and hyperopia was treated with WFO correction...
2018: Clinical Ophthalmology
María Elena Rodríguez González-Herrero, Marcos Ruiz, Francisco Javier López Román, José María Marín Sánchez, Joan Carles Domingo
Objective: There is little evidence of real-life outcomes of dietary supplementation with high-dose docosahexaenoic acid (DHA) and carotenoids in patients with diabetic retinopathy (DR). We assessed the effect of supplementation with DHA triglyceride (1,050 mg/d) + xanthophyll carotenoid multivitamin on macular function in nonproliferative DR. Methods: Asymptomatic patients with nonproliferative DR were included in a prospective controlled study and assigned (1:1) to the DHA supplementation group or the control group...
2018: Clinical Ophthalmology
Samiksha Fouzdar Jain, Helen H Song, Shaza N Al-Holou, Linda A Morgan, Donny W Suh
Purpose: The treatment of retinopathy of prematurity (ROP) is not standardized and can vary significantly between providers. This study aims to determine preferred practices in treating ROP by globally surveying pediatric ophthalmologists. Methods: Between January and February 2017, an international pediatric ophthalmology interest group was invited to complete an anonymous survey of 18 questions. The main objectives were to determine the preferred first line of treatment for ROP, the preferred dosage of intravitreal bevacizumab (IVB) used, and the outcome and possible complications following bevacizumab injection...
2018: Clinical Ophthalmology
Li Jiang, Scott Eaves, Navpreet Dhillon, Punithawathy Ranjit
Purpose: To assess and compare the long-term postoperative outcomes of trabeculectomy (TE), phacotrabeculectomy (PTE), and viscocanalostomy (VC) and to correlate postoperative intraocular pressure (IOP) with visual outcome. Patients and methods: This retrospective cohort observational study included 520 eyes which underwent TE with mitomycin C (MMC) (n=205), PTE with MMC (n=189), and VC ± combined cataract surgery and MMC (n=126) to control IOP between June 2010 and June 2014 by a single surgeon...
2018: Clinical Ophthalmology
Amanda Rey, Ignasi Jürgens, Xavier Maseras, Agnieszka Dyrda, Patricia Pera, Antonio Morilla
Purpose: To evaluate the visual outcomes and complications of phacoemulsification in previously vitrectomized eyes. Patients and methods: A retrospective analysis of 87 consecutive vitrectomized eyes (87 patients) which had undergone phacoemulsification with intraocular lens implantation between 2013 and 2016. Results: The mean interval from pars plana vitrectomy (PPV) to cataract surgery (CS) was 18.8 months. Mean age at CS was 61.5 years...
2018: Clinical Ophthalmology
Guzel Bikbova, Toshiyuki Oshitari, Takayuki Baba, Mukharram Bikbov, Shuichi Yamamoto
Diabetic keratopathy is characterized by impaired innervation of the cornea that leads to decreased sensitivity, with resultant difficulties with epithelial wound healing. These difficulties in wound healing put patients at risk for ocular complications such as surface irregularities, corneal infections, and stromal opacification. Pathological changes in corneal innervations in diabetic patients are an important early indicator of diabetic neuropathy. The decrease in corneal sensitivity is strongly correlated with the duration of diabetes as well as the severity of the neuropathy...
2018: Clinical Ophthalmology
Pear Pongsachareonnont, Sagol Tangjanyatam
Purpose: We compared the accuracy of axial length (AL) measurement obtained by optical biometry with that obtained by acoustic biometry in eyes with rhegmatogenous retinal detachment (RRD). Patients and methods: This prospective descriptive analytic study measured the AL of eyes with RRD preoperatively and 3 months postoperatively using optical biometry (intraocular lens [IOL] master group) and acoustic biometry (immersion A-scan group). Preoperative and postoperative measurements were compared by paired t -test...
2018: Clinical Ophthalmology
Ali Alsaqr, Ali Abu Sharha, Raied Fagehi, Awatif Almutairi, Sarah Alosaimi, Abdulrahman Almalki, Abdulaziz Alluwaymi
Purpose: The visual status of adolescents in Saudi Arabia (SA) has not been well reported. To date, the prevalence and types of refractive errors (REs), amblyopia, strabismus, and correctable visual impairments have not been quantified. The aim of the study was to investigate the visual status in adolescents in Riyadh, SA. Methods: This study was based on a population cross-sectional and random cluster design. After design and the sample calculations, 1,007 participants, 12-20 years of age, were screened during the study...
2018: Clinical Ophthalmology
Amr Mounir, Gamal Radwan, Mahmoud Mohamed Farouk, Engy Mohamed Mostafa
Objectives: To document the difference between complication rate in the early curve of practicing intracorneal stromal rings and after gaining experience. Patients and methods: A retrospective study of 623 eyes of 417 patients with keratoconus who underwent Keraring implantation using femtosecond laser for channel creation. Results: The main outcome measures were reported intraoperative and postoperative complications. The overall complication rate was 12...
2018: Clinical Ophthalmology
Justin B Hellman, Michele C Lim, Karen Y Leung, Cameron M Blount, Glenn Yiu
Purpose: To determine the financial and clinical impact of conversion from International Classification of Disease, 9th revision (ICD-9) to ICD-10 coding. Design: Retrospective, database study. Materials and methods: Monthly billing and coding data from 44,564 billable patient encounters at an academic ophthalmology practice were analyzed by subspecialty in the 1-year periods before (October 1, 2014, to September 30, 2015) and after (October 1, 2015, to September 30, 2016) conversion from ICD-9 to ICD-10...
2018: Clinical Ophthalmology
Thomas R Walters, Robert J Smyth-Medina, Paul C Cockrum
Purpose: The purpose of this study was to quantify the concentration of bromfenac in the aqueous humor utilizing high-performance liquid chromatography mass spectrometry between two commercial nonsteroidal anti-inflammatory drugs, using aqueous humor concentrations to characterize pharmacokinetic proportional differences between 0.075% bromfenac ophthalmic solution in DuraSite (BromSite® ) and 0.09% bromfenac ophthalmic solution (Bromday® ). Methods: In this multicenter, randomized, double-masked, two-arm, parallel-group, comparative, Phase II clinical trial, subjects were assigned to receive bromfenac in DuraSite or bromfenac ophthalmic solution in a 1:1 ratio...
2018: Clinical Ophthalmology
(no author information available yet)
[This corrects the article on p. 263 in vol. 12, PMID: 29440868.].
2018: Clinical Ophthalmology
Mohamed Nagy Elmohamady, Walid Abdelghaffar, Ahmed Daifalla, Tamer Salem
Purpose: To evaluate femtosecond laser in flap and cap creation, detect some corneal biomechanical changes, and evaluate dry eye after laser in situ keratomileusis (LASIK), Femto-LASIK, and small incision lenticule extraction (SMILE) with 3-year follow-up. Patients and methods: Preoperative evaluation taken: full ophthalmic examination, Pentacam, ocular response analyzer, ocular surface disease index (OSDI), and tear breakup time (TBUT). LASIK flap was created using Moria microkeratome in 30 eyes (LASIK group) and using VisuMax femtosecond laser in 38 eyes (FS-LASIK group) and SMILE was done by VisuMax in 35 eyes (SMILE group)...
2018: Clinical Ophthalmology
Beatrice Y Brewington, Yusra F Shao, Fredrick H Davidorf, Colleen M Cebulla
Surgical management with enucleation was the primary treatment for uveal melanoma (UM) for over 100 years. The Collaborative Ocular Melanoma Study confirmed in 2001 that globe-preserving episcleral brachytherapy for UM was safe and effective, demonstrating no survival difference with enucleation. Today, brachytherapy is the most common form of radiotherapy for UM. We review the history of brachytherapy in the treatment of UM and the evolution of the procedure to incorporate fine-needle-aspiration biopsy techniques with DNA-and RNA-based genetic prognostic testing...
2018: Clinical Ophthalmology
Tomoki Sato, Takahiro Kawaji, Akira Hirata, Takanori Mizoguchi
Purpose: The purpose of this study was to evaluate the efficacy of 360-degree suture trabeculotomy (360S-LOT) ab interno for treating open-angle glaucoma (OAG). Risk factors of surgical failure were examined. Patients and methods: 360S-LOT ab interno alone was performed for patients with uncontrolled OAG, and combined 360S-LOT ab interno/phacoemulsification was performed for patients with controlled OAG with a visually significant cataract between March 2014 and September 2015 at a single center...
2018: Clinical Ophthalmology
Jennifer S McDaniel, Andrew W Holt, Elaine D Por, Elof Eriksson, Anthony J Johnson, Gina L Griffith
Purpose: Currently available ocular moisture chambers are not adequate to manage the treatment of periocular burns, corneal injuries, and infection. The purpose of these studies was to demonstrate that a flexible, semi-transparent ocular wound chamber device adapted from technology currently used on dermal wounds is safe for use on corneal epithelial injuries. Materials and methods: A depilatory cream (Nair™, 30 seconds) was utilized to remove the excess hair surrounding the left eyes of anesthetized Institute Armand Frappier (IAF) hairless, female guinea pigs (Crl:HA-Hrhr)...
2018: Clinical Ophthalmology
Sergei V Churashov, Elena V Kudryashova, Alexei N Kulikov, Ernest V Boiko, Valerii F Chernysh, Dmitrii S Maltsev
Purpose: This study aimed to evaluate the efficacy of "wet" transepithelial phototherapeutic keratectomy (TE-PTK) for treating persistent epithelial defects (PEDs) in the corneal graft following penetrating keratoplasty (PKP). Methods: This study describes a noncomparative, prospective interventional case series. Patients with post-PKP graft epithelial defects lasting >3 months despite previous treatments with extensive wear soft contact lenses, amniotic membrane transplantation, and tarsorrhaphy were treated with wet TE-PTK...
2018: Clinical Ophthalmology
Danny Siu-Chun Ng, Zihan Sun, Alvin Lerrmann Young, Simon Tak-Chuen Ko, Jerry Ka-Hing Lok, Timothy Yuk-Yau Lai, Shameema Sikder, Clement C Tham
Objective: To identify residents' perceived barriers to learning phacoemulsification surgical procedures and to evaluate whether virtual reality simulation training changed these perceptions. Design: The ophthalmology residents undertook a simulation phacoemulsification course and proficiency assessment on the Eyesi system using the previously validated training modules of intracapsular navigation, anti-tremor, capsulorrhexis, and cracking/chopping. A cross-sectional, multicenter survey on the perceived difficulties in performing phacoemulsification tasks on patients, based on the validated International Council of Ophthalmology's Ophthalmology Surgical Competency Assessment Rubric (ICO-OSCAR), using a 5-point Likert scale (1 = least and 5 = most difficulty), was conducted among residents with or without prior simulation training...
2018: Clinical Ophthalmology
Manoj Motwani
Purpose: The aim of this article was to demonstrate how WaveLight Contoura and wavefront optimization (WFO) can be used together to treat high myopia/myopic astigmatism corrections. Materials and methods: A retrospective analysis was conducted on 24 consecutive myopic/myopic astigmatism eyes that exceeded the Contoura labeling of -8.00 with -3.00 D of astigmatism. Residual correction after Contoura with Layer Yolked Reduction of Astigmatism protocol was treated with WFO Contoura LASIK correction...
2018: Clinical Ophthalmology
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