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Clinical Ophthalmology

Anadi Khatri, Eli Pradhan, Sweta Singh, Roshija Rijal, Bal Kumar Khatri, Gyanendra Lamichhane, Muna Kharel
Aim: Subthreshold lasers have gained popularity in the treatment of chorioretinopathy central serous chorioretinopathy (CSCR) and yellow (577 nm) lasers have completely revolutionized the treatment. However, there is very little literature regarding the use of a more common and conventional - green (532 nm) subthreshold laser for the treatment of chronic CSCR. We report the use of green (532 nm) laser for the treatment of chronic CSCR and its outcome. Methods: Eyes with nonresolving CSCR were treated with green subthreshold laser and evaluated at the end of 5 months...
2018: Clinical Ophthalmology
Tao Sha, Lili Gao, Li Xue, Zhilong Zhang
No abstract text is available yet for this article.
2018: Clinical Ophthalmology
Yoshiaki Tanaka, Fumihiko Toyoda, Machiko Shimmura-Tomita, Nozomi Kinoshita, Hiroko Takano, Yoh Dobashi, Shigeki Yamada, Hiroto Obata, Akihiro Kakehashi
Purpose: The aim of this case series was to clarify the clinicopathological features of epiretinal membranes (ERMs) that developed in eyes after silicone oil (SO) tamponade to treat rhegmatog-enous retinal detachments (RRDs). Patients and methods: In the Department of Ophthalmology, Saitama Medical Center, Jichi Medical University, patients with idiopathic ERMs (23 eyes) and ERMs in eyes filled with SO (SO ERMs) after vitreous surgery to treat RRDs (nine eyes) were enrolled from July 2012 to March 2014...
2018: Clinical Ophthalmology
Saeed Azizi, Abdirahman Osman, Omer Ali
No abstract text is available yet for this article.
2018: Clinical Ophthalmology
Lily Dasso, Tala Al-Khaled, Sriram Sonty, Ahmad A Aref
Netarsudil ophthalmic solution is a novel topical intraocular pressure (IOP)-lowering agent that has recently been approved by the US Food and Drug Administration (FDA) for the treatment of ocular hypertension and open-angle glaucoma. Its unique pharmacology allows for IOP lowering as a result of direct reduction in trabecular outflow resistance in addition to a decrease in episcleral venous pressure and aqueous humor production. The efficacy of netarsudil has been shown in animal studies and human clinical trials...
2018: Clinical Ophthalmology
Majid Moshirfar, Jordan D Desautels, Brian D Walker, Orry C Birdsong, David F Skanchy, Tyler S Quist, Michael S Murri, Steve H Linn, Phillip C Hoopes, Phillip C Hoopes
Purpose: To assess longitudinal refractive, keratometric, and topographic changes following KAMRA small-aperture inlay implantation. Design and setting: Prospective study at a single site refractive surgery center. Methods: Fifty patients underwent KAMRA small-aperture corneal inlay implantation for the correction of presbyopia. Uncorrected near visual acuity (UNVA), uncorrected distance visual acuity, manifest refractive spherical equivalent (MRSE), mean keratometry (Km), corneal topography, and surgically induced astigmatism vector analysis assessments were performed preoperatively and at 1, 3, 6, 12, 24, and 36 months postoperatively...
2018: Clinical Ophthalmology
Joseph Tauber, Barry A Schechter, Jason Bacharach, Melissa M Toyos, Robert Smyth-Medina, Sidney L Weiss, Jodi I Luchs
Purpose: The aim of this study was to evaluate the safety and efficacy of OTX-101, a clear nanomicellar aqueous solution of cyclosporine, in the treatment of dry eye disease (DED). Patients and methods: This was a 12-week multicenter, randomized, prospective, double-masked, vehicle-controlled, dose-ranging clinical trial. Subjects were adults aged ≥18 years, with a total conjunctival staining score of ≥3 and ≤9, and global DED symptom score ≥40 (0-100 visual analogue scale)...
2018: Clinical Ophthalmology
Takeshi Teshigawara, Akira Meguro, Nobuhisa Mizuki
Purpose: To evaluate the influence of pupil dilation on predicted postoperative refraction (PPR) and recommended intraocular lens (IOL) power to obtain target postoperative refraction calculated by using the third- and fourth-generation IOL power calculation formulas with a new optical biometer. Methods: This retrospective study included 162 eyes with cataract that underwent uneventful phacoemulsification with IOL implantation. PPR, recommended IOL power, anterior chamber depth (ACD), and lens thickness (LT) were measured pre- and post-pupil dilation...
2018: Clinical Ophthalmology
Apatsa Lekskul, Pichaya Chuephanich, Chao Charoenkijkajorn
Purpose: To evaluate the postoperative refraction of intended undercorrection after intraocular lens (IOL) implantation in pediatric cataract patients. Design: A cross-sectional study (data collected by retrospective chart review). Patients and methods: The medical records of children aged under 10 years, who underwent cataract surgery with IOL implantation at the Ramathibodi Hospital between January 2000 and May 2018, were reviewed. IOL power calculations were 30%, 25%, 20%, 15% and 10% under-corrected if children were aged 6-12, 13-24, 25-36, 37-48 and 49-60 months, respectively...
2018: Clinical Ophthalmology
Alison D Early, Sarah Adelson, Craig J Miller, Thomas F Mauger
Objective: To evaluate smoking and alcohol use as risk factors for higher-grade dysplasia in a population of patients with histopathologically proven ocular surface squamous neoplasia. Materials and methods: This is a retrospective chart review of data extracted from a database comprising demographic information and medical diagnosis information based on International Classification of Disease codes. Outcome measures were analyzed using the Wilcoxon two-sided test, a non-parametric t -test...
2018: Clinical Ophthalmology
Carson R Bee, Lisa R Koenig, Eileen S Hwang, Steven B Koenig
Purpose: Treatment of calcific band keratopathy (CBK) is commonly performed with ethylenediaminetetraacetic acid (EDTA), but EDTA has become more difficult to obtain. This paper describes a technique for treating CBK using a diamond-dusted burr without EDTA in eyes with limited visual potential. Patients and methods: In this paper, we provide detailed instructions on how to perform the surgical technique for treating CBK, along with a surgical video. We performed a retrospective review of consecutive patients with clinically significant CBK who underwent this procedure from December 2012 to July 2015...
2018: Clinical Ophthalmology
Shwu-Jiuan Sheu, Ying-Yen Lee, Yu-Harn Horng, Huey-Shyan Lin, Wei-Yu Lai, Chui-Lien Tsen
Purpose: To investigate optical coherence tomography (OCT) characteristics in diabetic macular edema (DME) over time and after treatment. Patients and methods: OCT morphological features in DME eyes treated with ranibizumab with at least 1 year of follow-up were retrospectively analyzed. Results: Thirty-five eyes were included. From baseline to Month 12, mean visual gain was 7.2±13.6 letters and mean central retinal thickness reduction was 61...
2018: Clinical Ophthalmology
Pear Pongsachareonnont, Michael Ying Kit Mak, Cameron Paul Hurst, Wai-Ching Lam
Purpose: To determine the levels of interleukin (IL)-6, vascular endothelial growth factor-A, platelet-derived growth factor, placental growth factor (PLGF), and other cytokines in the aqueous fluid of patients with neovascular age-related macular degeneration who respond poorly to ranibizumab. Patients and methods: This is an observational, prospective study. Thirty-two eyes from 30 patients were included in the study: 11 patients who responded poorly to ranibizumab and were switched to aflibercept (AF group), 8 patients who received ranibizumab and photodynamic therapy (PDT group), and 13 patients who responded to ranibizumab (control group)...
2018: Clinical Ophthalmology
Soma Farag
No abstract text is available yet for this article.
2018: Clinical Ophthalmology
Nida Wongchaisuwat, Ankana Metheetrairat, Pratuangsri Chonpimai, Waree Nujoi, Pinnita Prabhasawat
Purpose: To compare the central corneal thickness (CCT) measurements in subjects with corneal edema using ultrasound pachymetry, Visante anterior-segment optical coherence tomography (OCT), Cirrus OCT, and Pentacam Scheimpflug camera tomography. Methods: This prospective cross-sectional study included 46 eyes of 33 patients with corneal edema and a CCT exceeding 550 μm evaluated by ultrasound pachymetry, Visante OCT, Cirrus OCT, and Pentacam. Two observers measured each eye twice...
2018: Clinical Ophthalmology
Fatemeh Eslami, Hamid Reza Ghasemi Basir, Abbas Moradi, Shokoufe Heidari Farah
Background: The prevalence of bacterial pathogens isolated from patients with acute and chronic dacryocystitis and the pattern of antibiotic susceptibility tests are varied in each region. Moreover, the management of dacryocystitis is only based on clinical observations without microbiological evaluation. The present study aimed to identify epidemiologic and etiologic factors of dacryocystitis in our geographical area. Materials and methods: This cross-sectional and analytical study was carried out in the ophthalmology department of Hamadan University of Medical Sciences (northwest of Iran) during 2016-2017...
2018: Clinical Ophthalmology
Christopher Ricks, Alexandrea Montoya, Jeff Pettey
Background: Solar retinopathy is a rare ophthalmic disorder resulting from sustained viewing of the sun without protective eyewear. Incidence of solar retinopathy typically increases following a solar eclipse due to attempted visualization of the sun without appropriate eye protection. This paper serves as a case series of all available reported cases of solar retinopathy present in Utah resulting from the August 21st, 2017 solar eclipse. Methods: Twenty-seven patients had presented with concern for vision changes after the solar eclipse and six patients had exam findings consistent with solar retinopathy...
2018: Clinical Ophthalmology
Eiko Tsuiki, Kiyoshi Suzuma, Makiko Matsumoto, Yasser Helmy Mohamed, Takashi Kitaoka
Purpose: This study was designed to investigate the therapeutic effects of oral kallidinogenase medication as an adjuvant therapy in treating patients with diabetic macular edema (DME). Study design: This was a prospective, open-labeled, randomized study. Methods: All patients were given posterior sub-Tenon triamcinolone acetonide (STTA) injection and focal laser treatment session for DME. The patients were subdivided into two groups: 1) those treated with oral kallidinogenase for at least 6 months after local treatment (treated group) and 2) those treated without oral kallidinogenase (untreated group)...
2018: Clinical Ophthalmology
Yasutaka Takagi, Kazunori Santo, Masayo Hashimoto, Takeo Fukuchi
Purpose: This paper aimed to evaluate the intraocular pressure (IOP)-lowering effects of prostaglandin analogs (PGAs) in Japanese patients with normal-tension glaucoma (NTG) by reviewing the current literature. Methods: In February 2018, database searches were performed in PubMed, Embase, ProQuest, and the Japanese databases JAPICDOC and JMEDPlus. Studies were sorted into two categories: Category 1 consisted of studies of patients with NTG who reported reduced IOP values and Category 2 consisted of studies of patients with NTG who had IOP values at predosing and a final evaluation point...
2018: Clinical Ophthalmology
Yoichiro Masuda, Hisaharu Iwaki, Akira Watanabe, Akiko Takada, Toshinori Okamoto, Kotaro Oki, Tadashi Nakano, Hiroshi Tsuneoka
Femtosecond laser-assisted cataract surgery (FLACS) changes the intraoperative environment due to the generation of intracapsular gas that induces a high intracapsular volume. Manual hydrodissection (mH) may induce high intracapsular pressure (ICP) and additional intracapsular volume, thereby leading to capsular block syndrome (CBS). Since the phaco-sleeve irrigation-assisted hydrodissection (iH) technique is used to initially groove and split the lens and remove the intracapsular gas, this can reduce the intracapsular volume while bypassing the intracapsular lens prior to the hydrodissection...
2018: Clinical Ophthalmology
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