journal
MENU ▼
Read by QxMD icon Read
search

Clinical Ophthalmology

journal
https://www.readbyqxmd.com/read/29026287/ocular-pharmacokinetics-and-tolerability-of-bimatoprost-ophthalmic-solutions-administered-once-or-twice-daily-in-rabbits-and-clinical-dosing-implications
#1
Jie Shen, Margot L Goodkin, Warren Tong, Mayssa Attar
PURPOSE: Fixed-combination medications can benefit patients requiring multiple agents to lower their intraocular pressure (IOP), but combining agents with complementary mechanisms of action is challenging if their dosing frequency differs. This study compares in vivo pharmacokinetic and ocular tolerability of bimatoprost 0.01% ophthalmic solutions dosed once or twice daily. Reports of twice-daily dosing in glaucoma patients are also reviewed. METHODS: New Zealand White rabbits were administered bimatoprost 0...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29026286/intraoperative-optical-coherence-tomography-and-ab-interno-trabecular-meshwork-surgery-with-the-trabectome
#2
Bernd Junker, Jens F Jordan, Carsten Framme, Amelie Pielen
IMPORTANCE: This study is the first description of the use of the intraoperative optical coherence tomography (iOCT) for trabecular meshwork surgery with the Trabectome in a regular clinical setting. BACKGROUND: The aim of this study is to evaluate intraoperatively the immediate success of ab interno trabeculotomy with the Trabectome defined as a removal of the trabecular meshwork. DESIGN: This is a retrospective clinical study performed in the University Eye Hospital, Medical School Hannover...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29026285/efficacy-of-0-05-epinastine-and-0-1-olopatadine-for-allergic-conjunctivitis-as-seasonal-and-preseasonal-treatment
#3
Takanori Mizoguchi, Mineo Ozaki, Nobuchika Ogino
PURPOSE: To evaluate the efficacy and safety of 0.05% epinastine and 0.1% olopatadine eye drop preparations as seasonal and preseasonal treatments in patients with seasonal allergic conjunctivitis (SAC). SUBJECTS AND METHODS: This was a prospective, randomized, case-control study involving two institutions. The subjects were patients diagnosed with SAC at two institutions between February and March in 2014. To examine the clinical effects of seasonal treatment, 0...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29026284/anti-vascular-endothelial-growth-factor-therapy-for-the-treatment-of-myopic-choroidal-neovascularization
#4
REVIEW
Colin S Tan, SriniVas R Sadda
Myopic choroidal neovascularization (CNV) is a sight-threatening condition which occurs in eyes with myopia, particularly in those with pathologic myopia. It is the most common cause of CNV among patients younger than 50 years. Hemorrhage and exudation from the CNV lesion may eventually result in scarring or chorioretinal atrophy. While myopic CNV was previously treated with focal laser photocoagulation or photodynamic therapy (PDT), the current treatment of choice is anti-vascular endothelial growth factor (VEGF) agents...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29026283/outcomes-study-between-femtosecond-laser-assisted-cataract-surgery-and-conventional-phacoemulsification-surgery-using-an-active-fluidics-system
#5
Wilson Takashi Hida, Patrick Frenzel Tzelikis, César Vilar, Mario Augusto Pereira Dias Chaves, Antônio Francisco Pimenta Motta, Pedro Carlos Carricondo, Bruna Vieira Ventura, Renato Ambrosio, Walton Nosé, Milton Ruiz Alves
PURPOSE: The purpose of this study was to compare intraoperative parameters between femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification using Centurion(®) Vision System with Active Fluidics. SETTING: This study was performed at Brasília Ophthalmologic Hospital, Brasília, Federal District, Brazil. PATIENTS AND METHODS: This was a prospective randomized comparative study. Patients with the diagnosis of cataract and surgical extraction programmed were divided into two groups: conventional phacoemulsification and FLACS...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28979096/ectasia-following-small-incision-lenticule-extraction-smile-a-review-of-the-literature
#6
REVIEW
Majid Moshirfar, Julio C Albarracin, Jordan D Desautels, Orry C Birdsong, Steven H Linn, Phillip C Hoopes
PURPOSE: Four cases of corneal ectasia after small-incision lenticule extraction (SMILE) have been reported. In this review, we provide an overview of the published literature on corneal ectasia after SMILE and risk factors associated with this complication. METHODS: Case reports were identified by a search of seven electronic databases for pertinent heading terms between 2011 and July 2017. We identified patient characteristics and surgical details including preoperative topography, central corneal thickness, and anterior keratometry (Km)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28979095/comparison-of-intraocular-pressure-fluctuations-before-and-after-ab-interno-trabeculectomy-in-pseudoexfoliation-glaucoma-patients
#7
Naoki Tojo, Shinya Abe, Mari Miyakoshi, Atsushi Hayashi
PURPOSE: Ab interno trabeculectomy (AIT) with the Trabectome has been shown to reduce intraocular pressure (IOP) in eyes with pseudoexfoliation (PEX) glaucoma. Here, we examined the change of IOP fluctuations before and after only AIT or AIT with cataract surgery in PEX patients using the contact lens sensor Triggerfish(®). METHODS: This was a prospective open-label study. Twenty-four consecutive patients with PEX glaucoma were included. Twelve patients underwent cataract surgery and AIT (triple-surgery group), and 12 patients underwent only AIT (single-surgery group)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28979094/ocular-parameters-before-and-after-steep-trendelenburg-positioning-for-robotic-assisted-laparoscopic-radical-prostatectomy
#8
Kyoichi Mizumoto, Masahiko Gosho, Masayoshi Iwaki, Masahiro Zako
PURPOSE: Intraocular pressure (IOP) increases in patients in a steep Trendelenburg position during robotic-assisted laparoscopic radical prostatectomy (RALP). We hypothesized that a steep Trendelenburg position during RALP, an unusual systemic condition involving a transiently increased IOP, may induce ocular pathology that can be detected by detailed evaluations long after the surgery. This study aims to explore ocular structural and functional parameters in patients before and in the long term after the surgery...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28979093/investigating-the-potential-benefits-of-a-new-artificial-tear-formulation-combining-two-polymers
#9
Peter A Simmons, Joseph G Vehige
PURPOSE: Artificial tear formulations typically contain a water-soluble polymer to enhance residence time, moisture retention, and binding to the mucin coat of the ocular surface, which facilitate corneal healing. This study investigated the potential advantages of combining carboxymethylcellulose (CMC) and hyaluronic acid (HA) polymers in a single formulation. MATERIALS AND METHODS: Individual CMC and HA solutions were prepared and tested for bulk viscosity in comparison to a solution that combined CMC and HA...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28979092/image-registration-reveals-central-lens-thickness-minimally-increases-during-accommodation
#10
Ronald A Schachar, Majid Mani, Ira H Schachar
PURPOSE: To evaluate anterior chamber depth, central crystalline lens thickness and lens curvature during accommodation. SETTING: California Retina Associates, El Centro, CA, USA. DESIGN: Healthy volunteer, prospective, clinical research swept-source optical coherence biometric image registration study of accommodation. METHODS: Ten subjects (4 females and 6 males) with an average age of 22.5 years (range: 20-26 years) participated in the study...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28979091/intraocular-pressure-and-visual-field-changes-in-normal-tension-glaucoma-patients-treated-using-either-unoprostone-or-latanoprost-a-prospective-comparative-study
#11
Daisuke Takemoto, Tomomi Higashide, Yoshiaki Saito, Shinji Ohkubo, Sachiko Udagawa, Hisashi Takeda, Kazuhisa Sugiyama
PURPOSE: We conducted a prospective study in patients with normal-tension glaucoma (NTG) who received either isopropyl unoprostone or latanoprost. We compared the drugs in terms of their effects on intraocular pressure (IOP) and visual field loss progression over a 3-year period. STUDY DESIGN: Prospective, randomized controlled study. METHODS: We enrolled 48 patients with newly diagnosed NTG at Kanazawa University Hospital. Eligible patients were randomly allocated (1:1) to receive either unoprostone or latanoprost ophthalmic solutions...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28979090/effects-of-temperature-and-fluid-media-on-the-scroll-width-size-of-the-descemet-s-membrane-endothelial-keratoplasty-dmek-donor-graft
#12
Ellen H Koo, Allen O Eghrari, Ryan S Meshkin, Wei Shi, William J Feuer, Karen G DeMarco, Arthur C Kurz
AIM: Our study was conducted to evaluate whether higher temperature leads to increased - or wider - scroll widths of the Descemet's membrane endothelial keratoplasty (DMEK) donor graft. PURPOSE: To investigate the effects of temperature and fluid media on the DMEK donor graft scroll widths. MATERIALS AND METHODS: This research work was a laboratory investigation. Baseline cell count was taken via specular microscopy for the donor corneas at room temperature (20°C-25°C)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28979089/long-term-evaluation-of-spontaneous-release-of-epiretinal-membrane-and-its-possible-pathogenesis
#13
Teruyo Kida, Seita Morishita, Masanori Fukumoto, Takaki Sato, Hidehiro Oku, Tsunehiko Ikeda
PURPOSE: To investigate the characteristics in spontaneous release of epiretinal membrane (ERM) during watchful waiting and to introduce a possible mechanism of pathogenesis as a photo essay. METHODS: Records from all patients with ERM were obtained from Osaka Medical College Hospital from January 2001 to October 2012. Visual acuity (VA), fundus photo, and optical coherence tomography (OCT) were reviewed using the medical records. For statistical analysis, VA measured with a Landolt chart was converted to the logarithm of the minimum angle of resolution (logMAR)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28919703/quality-and-learning-curve-of-handheld-versus-stand-alone-non-mydriatic-cameras
#14
Mariya Gosheva, Christian Klameth, Lars Norrenberg, Lucien Clin, Johannes Dietter, Wadood Haq, Iliya V Ivanov, Focke Ziemssen, Martin A Leitritz
PURPOSE: Nowadays, complex digital imaging systems allow detailed retinal imaging without dilating patients' pupils. These so-called non-mydriatic cameras have advantages in common circumstances (eg, for screening or emergency purposes) but present limitations in terms of image quality and field of view. We compare the usefulness of two non-mydriatic camera systems (ie, a handheld versus a stand-alone device) for fundus imaging. The primary outcome was image quality. The secondary outcomes were learning effects and quality grade-influencing factors...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28919702/micro-invasive-glaucoma-surgery-migs-a-review-of-surgical-procedures-using-stents
#15
Lutz E Pillunat, Carl Erb, Anselm Gm Jünemann, Friedemann Kimmich
Over the last decade several novel surgical treatment options and devices for glaucoma have been developed. All these developments aim to cause as little trauma as possible to the eye, to safely, effectively, and sustainably reduce intraocular pressure (IOP), to produce reproducible results, and to be easy to adopt. The term "micro-invasive glaucoma surgery (MIGS)" was used for summarizing all these procedures. Currently MIGS is gaining more and more interest and popularity. The possible reduction of the number of glaucoma medications, the ab interno approach without damaging the conjunctival tissue, and the probably safer procedures compared to incisional surgical methods may explain the increased interest in MIGS...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28894356/refractive-lens-exchange-in-younger-and-older-presbyopes-comparison-of-complication-rates-3-months-clinical-and-patient-reported-outcomes
#16
Steven C Schallhorn, Julie M Schallhorn, Martina Pelouskova, Jan A Venter, Keith A Hettinger, Stephen J Hannan, David Teenan
PURPOSE: To compare refractive and visual outcomes, patient satisfaction, and complication rates among different age categories of patients who underwent refractive lens exchange (RLE). METHODS: A stratified, simple random sample of patients matched on preoperative sphere and cylinder was selected for four age categories: 45-49 years (group A), 50-54 years (group B), 55-59 years (group C), and 60-65 years (group D). Each group contained 320 patients. All patients underwent RLE with a multifocal intraocular lens at least in one eye...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28894355/erratum-intravitreal-aflibercept-for-choroidal-neovascularization-associated-with-chorioretinitis-a-pilot-study-corrigendum
#17
(no author information available yet)
[This corrects the article on p. 1315 in vol. 11, PMID: 28769551.].
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28894354/switching-to-preservative-free-latanoprost-impact-on-tolerability-and-patient-satisfaction
#18
COMMENT
Daniel Edward Robert Beck, Karim El-Assal, Ken McGarry, Nicholas Kloster Wride
No abstract text is available yet for this article.
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28883712/integrated-results-from-the-copernicus-and-galileo-studies
#19
Amelie Pielen, W Lloyd Clark, David S Boyer, Yuichiro Ogura, Frank G Holz, Jean-Francois Korobelnik, Brigitte Stemper, Friedrich Asmus, Kay D Rittenhouse, Christiane Ahlers, Robert Vitti, Namrata Saroj, Oliver Zeitz, Julia A Haller
OBJECTIVES: To report on the efficacy and safety of intravitreal aflibercept in patients with macular edema secondary to central retinal vein occlusion (CRVO) in an integrated analysis of COPERNICUS and GALILEO. PATIENTS AND METHODS: Patients were randomized to receive intravitreal aflibercept 2 mg every 4 weeks or sham injections until week 24. From week 24 to week 52, all intravitreal aflibercept-treated patients in both studies and sham-treated patients in COPERNICUS were eligible to receive intravitreal aflibercept based on prespecified criteria...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28860706/investigation-into-the-quantitative-and-qualitative-characteristics-of-choroidal-melanoma-through-magnetic-resonance-imaging-and-b-scan-ultrasound
#20
Vassilis Papayiannis, Konstantinos T Tsaousis, Constantinos A Kouskouras, Afroditi Haritanti, Vasilios F Diakonis, Ioannis T Tsinopoulos
OBJECTIVE: To investigate the homogeneity and vascularity of choroidal melanoma through magnetic resonance imaging (MRI) and brightness modulation (B-mode) ultrasound scan and their correlation with dimensions of tumor, as well as to measure the sensitivity of both modalities in retinal detachment (RD) detection. MATERIALS AND METHODS: This retrospective chart review included patients diagnosed with choroidal melanoma. All these patients underwent MRI scans using T2-weighted (T2-WI) and T1-weighted (T1-WI) sequences, before and after an intravenous injection of paramagnetic contrast material...
2017: Clinical Ophthalmology
journal
journal
41819
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"