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Clinical Ophthalmology

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https://www.readbyqxmd.com/read/29445264/exercise-program-improved-subjective-dry-eye-symptoms-for-office-workers
#1
Kokoro Sano, Motoko Kawashima, Sayuri Takechi, Masaru Mimura, Kazuo Tsubota
Introduction: We investigated the benefits of a cognitive behavior therapy-based exercise program to reduce the dry eye symptoms of office workers. Materials and methods: We recruited 11 office workers with dry eye symptoms, aged 31-64 years, who voluntarily participated in group health guidance at a manufacturing company. Participants learned about the role of physical activity and exercise in enhancing wellness and performed an exercise program at home 3 days per week for 10 weeks...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29440873/effect-of-phenylephrine-ketorolac-on-iris-fixation-ring-use-and-surgical-times-in-patients-at-risk-of-intraoperative-miosis
#2
Denise Visco
Purpose: To evaluate the effect of intracameral phenylephrine/ketorolac (1%/0.3%) during cataract surgery on the use of iris fixation ring and surgical time in patients with poor pupil dilation (≤5.0 mm) or intraoperative floppy iris syndrome (IFIS). Setting: Private practice outpatient surgical center. Design: This retrospective analysis was conducted from January 1, 2014 to October 7, 2015. Materials and methods: The use of iris fixation rings was evaluated in a retrospective analysis of 46 patients who underwent cataract surgery from January 1, 2014, to October 7, 2015, and who were identified before surgery to be at risk for intraoperative miosis...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29440872/topical-ocular-0-1-cyclosporine-a-cationic-emulsion-in-dry-eye-disease-patients-with-severe-keratitis-experience-through-the-french-early-access-program
#3
Pierre-Jean Pisella, Marc Labetoulle, Serge Doan, Beatrice Cochener-Lamard, Mourad Amrane, Dahlia Ismail, Catherine Creuzot-Garcher, Christophe Baudouin
Purpose: The objective of this study was to report the evaluation of efficacy and safety of cyclosporine A cationic emulsion (CsA CE) 0.1% for the treatment of severe keratitis in adults with dry eye disease (DED) in a French early-access program. Methods: Patients with DED and severe keratitis (corneal fluorescein staining [CFS] score of 3-5 on the Oxford scale and/or the presence of corneal lesions [filaments or ulcers]) were enrolled in a compassionate use program (Authorization for Temporary Use [ATU]) for once-daily CsA CE, which was approved by French health authorities prior to its registration...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29440871/erratum-micro-invasive-glaucoma-surgery-migs-a-review-of-surgical-procedures-using-stents-corrigendum
#4
(no author information available yet)
[This corrects the article on p. 1583 in vol. 11, PMID: 28919702.].
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29440870/surgical-outcomes-of-membrane-tube-type-glaucoma-shunt-device-in-indigenous-west-africans
#5
Olusola Olawoye, Tarela Sarimiye, Adeyinka Ashaye, Young Hoon Hwang, Jong Chul Han, Byung Heon Ahn
Purpose: The aim of this study was to report the safety and efficacy of the membrane-tube (MT)-type glaucoma shunt device (Finetube MT) in the management of refractory glaucoma in indigenous West Africans. Methods: The Finetube MT was implanted into 25 eyes of 25 West African patients with refractory glaucoma. These patients had inadequate intraocular pressure (IOP) control despite maximum tolerable IOP-lowering medications with or without previous ocular surgeries...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29440869/exfoliation-syndrome-in-northern-nigeria
#6
Ugbede Idakwo, Olusola Olawoye, Benedictus Gk Ajayi, Robert Ritch
Purpose: To estimate the frequency of exfoliation syndrome (XFS) and its association with ocular diseases in Northern Nigeria. Materials and methods: Consecutive patients who presented to the outpatient department of ECWA Eye Hospital Kano from February 2015 to May 2015 were included in the study. Each patient had a complete ophthalmic examination. The anterior segment examination included tonometry, gonioscopy, and detailed slit-lamp examination to assess for the presence or absence of exfoliation material, inflammatory cells, and other abnormal findings...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29440868/ocular-comfort-assessment-of-lifitegrast-ophthalmic-solution-5-0-in-opus-3-a-phase-iii-randomized-controlled-trial
#7
Kelly K Nichols, Edward Holland, Melissa M Toyos, James H Peace, Parag Majmudar, Aparna Raychaudhuri, Mohamed Hamdani, Monica Roy, Amir Shojaei
Purpose: To evaluate ocular comfort of lifitegrast ophthalmic solution 5.0% among patients with dry eye disease (DED) in the OPUS-3 trial. Methods: OPUS-3 was a multicenter, randomized, double-masked, placebo-controlled study. Adults with DED and recent artificial tear use were randomized 1:1 (lifitegrast:placebo) to ophthalmic drops twice daily for 84 days. On days 0 (baseline), 14, 42, and 84, drop comfort score (scale, 0-10; 0 = very comfortable, 10 = very uncomfortable) was measured at 0, 1, 2, and 3 minutes postinstillation...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29440867/long-term-titrated-iop-control-with-one-two-or-three-trabecular-micro-bypass-stents-in-open-angle-glaucoma-subjects-on-topical-hypotensive-medication-42-month-outcomes
#8
L Jay Katz, Carl Erb, Amadeu Carceller Guillamet, Antonio M Fea, Lilit Voskanyan, Jane Ellen Giamporcaro, Dana M Hornbeak
Purpose: Evaluate long-term outcomes after one, two, or three trabecular micro-bypass stents implanted in a standalone procedure in eyes with open-angle glaucoma taking ocular hypotensive medication. Patients and methods: Prospective randomized ongoing study of 119 subjects (109 with 42-month follow-up) with open-angle glaucoma, preoperative intraocular pressure (IOP) 18-30 mmHg on one to three glaucoma medications, and unmedicated (post-washout) IOP 22-38 mmHg...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29440866/long-term-progression-of-visual-field-defects-and-related-factors-in-medically-treated-normal-tension-glaucoma
#9
Keiji Yoshikawa, Kazunori Santo, Hiroko Hizaki, Masayo Hashimoto
Purpose: To analyze factors related to long-term progression of visual field defects (VFD) in patients with normal tension glaucoma (NTG) under medical therapy. Patients and methods: Clinical data from 622 eyes of 311 primary open-angle glaucoma and NTG patients were collected from April 2006 to March 2016. Of these patients, those with normal intraocular pressure (IOP); glaucomatous VFD judged by Anderson's criteria; corrected visual acuity ≥0.7; receiving more than 6 years medical therapy; having undergone ≥10 visual field tests performed at 6-month intervals using a Humphrey field analyzer (Swedish Interactive Threshold Algorithms standard, C 24-2 program); and having reliability coefficients of visual field testing <33% and mean deviation (MD) more than -20 decibels in the initial visual field test were included in data analysis...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29416315/comparison-of-corneal-biomechanics-after-myopic-small-incision-lenticule-extraction-compared-to-lasik-an-ex-vivo-study
#10
Anastasios John Kanellopoulos
Purpose: To investigate ex vivo potentially different corneal biomechanical properties after small-incision lenticule extraction (SMILE) versus LASIK for myopic correction. Methods: Thirty human donor corneas were subjected to either myopic SMILE or femtosecond laser-assisted LASIK. Donor corneas were assigned to six investigative groups: Group A, -3.00 D (diopters) SMILE; Group B, -8.00 D SMILE; Group C, -3.00 D LASIK; and Group D, -8.00 D LASIK. Additionally, two control groups were formed: Group E, SMILE and Group F, LASIK...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29416314/cysteamine-hydrochloride-eye-drop-solution-for-the-treatment-of-corneal-cystine-crystal-deposits-in-patients-with-cystinosis-an-evidence-based-review
#11
REVIEW
Achini K Makuloluwa, Fatemeh Shams
Cystinosis is a rare, autosomal recessive disorder leading to defective transport of cystine out of lysosomes. Subsequent cystine crystal accumulation can occur in various tissues, including the ocular surface. This review explores the efficacy of cysteamine hydrochloride eye drops in the treatment of corneal cystine crystal accumulation and its safety profile.
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29416313/measurement-of-the-hypotenuse-of-the-vertical-optic-nerve-head-cup-with-spectral-domain-optical-coherence-tomography-for-the-structural-diagnosis-of-glaucoma
#12
Fabio Lavinsky, Camila Zanella Benfica, Nédio Castoldi, Anne Elise Cruz do Carmo Chaves, Paulo Augusto de Arruda Mello
Purpose: To evaluate the hypotenuse of the vertical optic nerve head cup (HVOC), measured using the length and depth of the cup obtained with enhanced depth imaging spectral-domain optic coherence tomography (SD-OCT), as a biomarker for glaucoma diagnosis. Methods: This was a prospective cross-sectional study of patients with glaucoma and controls. SD-OCT was performed in all participants to assess average circumpapillary retinal nerve fiber layer (RNFL) thickness...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29406523/surgical-cystotomy-for-refractory-diabetic-cystoid-macular-edema
#13
COMMENT
Koushik Tripathy
No abstract text is available yet for this article.
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29403262/optical-coherence-tomography-angiography-in-choroidal-melanoma-and-nevus
#14
Fariba Ghassemi, Reza Mirshahi, Kaveh Fadakar, Siamak Sabour
Synopsis: In optical coherence tomography angiography, the choroidal vascular flow rate in choroidal melanoma is significantly lower than that in choroidal nevus. Objective: The objective of this study was to describe the choriocapillaris and retinal features imaged by optical coherence tomography angiography (OCTA) in eyes with choroidal nevus from small malignant choroidal melanoma. Methods: In this retrospective, noninvasive, observational study, 11 patients diagnosed with small choroidal mass (five with choroidal nevus and six with malignant melanoma) who underwent dilated fundus examination, ocular ultrasonography and OCTA images were compared...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29403261/maximum-human-objectively-measured-pharmacologically-stimulated-accommodative-amplitude
#15
Andrzej Grzybowski, Ronald A Schachar, Magdalena Gaca-Wysocka, Ira H Schachar, Barbara K Pierscionek
Purpose: To measure the maximum, objectively measured, accommodative amplitude, produced by pharmacologic stimulation. Methods: Thirty-seven healthy subjects were enrolled, with a mean age of 20.2±1.1 years, corrected visual acuity of 20/20, and mean spherical equivalent refraction (SER) =-0.83±1.60 diopters. For each subject, the right pupil was dilated with phenylephrine 10%. After 30 minutes, the pupil was measured, the left eye was patched, and the right eye was autorefracted...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29403260/evaluation-of-contrast-sensitivity-and-other-visual-function-outcomes-in-diabetic-macular-edema-patients-following-treatment-switch-to-aflibercept-from-ranibizumab
#16
Donald R Nixon, Nicholas Ap Flinn
Purpose: This study aims to investigate changes in contrast sensitivity (CS), visual acuity (VA), central retinal thickness (CRT), and vision-related quality of life in subjects with recalcitrant diabetic macular edema switched from long-term ranibizumab treatment to aflibercept. Patients and methods: In this prospective, investigator-masked, single-center study, 40 patients with persistent fluid, despite previous ranibizumab treatment, were switched to aflibercept with 5 consecutive monthly doses...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29398905/irrigation-port-hydration-in-phacoemulsification-surgery
#17
Hisaharu Suzuki, Yoichiro Masuda, Yuki Hamajima, Hiroshi Takahashi
Background: In most cases, hydration is performed by water injection into the stromal tissue with a needle. The technique is simple, however it is sometimes troublesome. Purpose: We describe a simple technique for hydrating the corneal stroma in cataract surgery using an irrigation port. Patients and methods: The technique began by pushing the irrigation port against the corneal stroma for a few seconds during phacoemulsification, which generated edema in the corneal incision that subsequently prevented leakage...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29398904/a-single-vectored-thermal-pulsation-treatment-for-meibomian-gland-dysfunction-increases-mean-comfortable-contact-lens-wearing-time-by-approximately-4-hours-per-day
#18
Caroline A Blackie, Christy A Coleman, Kelly K Nichols, Lyndon Jones, Peter Q Chen, Ron Melton, David L Kading, Leslie E O'Dell, Sruthi Srinivasan
Purpose: To evaluate the effect of a single vectored thermal pulsation (VTP) treatment in contact lens wearers with meibomian gland dysfunction (MGD) and dry eye symptoms. Methods: The prospective, nonsignificant risk, open-label, randomized, multi-center clinical trial included 55 soft contact lens (SCL) wearers with MGD and evaporative dry eye. Subjects were randomized to the single VTP treatment group or an untreated control. The controls received a crossover VTP treatment at 3 months (crossover treatment group)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29398903/comparison-of-a-single-dose-vectored-thermal-pulsation-procedure-with-a-3-month-course-of-daily-oral-doxycycline-for-moderate-to-severe-meibomian-gland-dysfunction
#19
Kerry B Hagen, Raman Bedi, Caroline A Blackie, Kellie J Christenson-Akagi
Purpose: The aim of this study was to compare the efficacy of a single bilateral 12-minute vectored thermal pulsation (VTP) procedure versus daily oral doxycycline for 3 months for moderate-to-severe meibomian gland dysfunction (MGD). Methods: This prospective, randomized, parallel-group, single-masked study included 28 subjects who received either a single-dose VTP or 3 months of doxycycline treatment. At baseline and 3 months post treatment, all subjects were evaluated for the following: dry eye symptoms with a standard dry eye questionnaire (the Standard Patient Evaluation for Eye Dryness [SPEED]), meibomian gland (MG) function by counting the number of glands yielding liquid secretion with the MG evaluator (MGE), tear breakup time (TBUT) and corneal and conjunctival staining...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29398902/elevated-levels-of-plasma-tumor-necrosis-factor-alpha-in-patients-with-pseudoexfoliation-glaucoma
#20
Altaf A Kondkar, Taif A Azad, Faisal A Almobarak, Hatem Kalantan, Saleh A Al-Obeidan, Khaled K Abu-Amero
Background: Tumor necrosis factor alpha (TNF-α) is a pro-inflammatory cytokine, which plays a role in glaucomatous neurodegeneration. Based on the plausible role of inflammation in the pathogenesis of pseudoexfoliation glaucoma (PEG), we investigated whether there is any relationship between the levels of plasma TNF-α and PEG or any of its clinical indices in comparison to normal controls. Methods: The study was designed as a retrospective analysis. Plasma samples from 49 PEG patients and 88 non-glaucomatous controls were evaluated for TNF-α levels using an enzyme-linked immunosorbent assay (ELISA)...
2018: Clinical Ophthalmology
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