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Clinical Ophthalmology

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https://www.readbyqxmd.com/read/29674843/intraoperative-complications-of-refractive-small-incision-lenticule-extraction-in-the-early-learning-curve
#1
Abdelmonem M Hamed, Shereef M Abdelwahab, Tarek T Soliman
Purpose: To study the intraoperative complications of refractive small incision lenticule extraction (ReSMILE push-up technique), and to record the mean intraoperative duration time of all surgeries for the refractive surgeon in his early learning curve. Setting: Ebsar Eye Center, Benha, Egypt. Design: A prospective, single-center, cohort clinical study. Methods: This prospective, single-center, cohort clinical study was done on patients with myopia and myopic astigmatism, who were enrolled for SMILE surgeries...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29670328/treatment-outcomes-in-the-dry-eye-amniotic-membrane-dream-study
#2
Marguerite B McDonald, Hosam Sheha, Sean Tighe, Susan B Janik, Frank W Bowden, Amit R Chokshi, Michael A Singer, Seema Nanda, Mujtaba A Qazi, Damon Dierker, Adam T Shupe, Brittany J McMurren
Purpose: To evaluate the efficacy of cryopreserved amniotic membrane (CAM) in reducing signs and symptoms of dry eye disease (DED) in a large patient population. Methods: A retrospective chart review at 10 clinical sites was done of patients with refractory DED who received CAM and completed at least 3 months of follow-up. Data collected were demographics; medical history including previous and current ocular treatment, diagnosis, clinical presentations, comorbidity, duration and frequency of treatment with CAM; and concomitant medications...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29670327/eye-wash-water-flow-direction-study-an-evaluation-of-the-effectiveness-of-eye-wash-devices-with-opposite-directional-water-flow
#3
Jennifer S Fogt, Lisa A Jones-Jordan, Joseph T Barr
Introduction: New designs of eye wash stations have been developed in which the direction of water flow from the fountain has been reversed, with two water streams originating nasally in both eyes and flowing toward the temporal side of each eye. No study has been done to determine the ideal direction of water flow coming from the eye wash in relation to the eye. Materials and methods: Ophthalmic eye examinations were conducted before and after the use of two eye wash stations with opposite water flow directionality...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29670326/iridocorneal-endothelial-syndrome-clinical-perspectives
#4
REVIEW
Andrew Walkden, Leon Au
This article aims to review the clinical management strategies available for the rare iridocorneal endothelial syndrome. The different clinical variations as well as the imaging techniques available to aid diagnosis are discussed. We then present the evidence available to help the reader to understand how the condition can be managed medically and also the important surgical aspects of treatment. This involves raised intraocular pressure management in addition to the visual management options of partial or full thickness keratoplasty...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29670325/retinal-detachment-in-albinism
#5
Ahmad M Mansour, Jay Chhablani, J Fernando Arevalo, Lihteh Wu, Ravi Sharma, Suthasinee Sinawat, Tharikarn Sujirakul, Alexandre Assi, Wandsy M Vélez-Vázquez, Mohamad A Mansour, Ozcan Kayikcioglu, Cem Kucukerdonmez, Ali Kal
Purpose: To report the visual and anatomic outcomes of albino retinal detachment (ARD) repair. Methods: Collaborative retrospective analysis of ARD. Outcome measures were number of surgical interventions, final retinal reattachment, and best corrected visual acuity (BCVA) at last follow-up. Results: Seventeen eyes of 16 patients (12 males; mean age =37.8 years) had the following complications at presentation: macula off (14), total (7) or inferior detachment (5), proliferative vitreoretinopathy (5), detectable break (16), lattice (5), horseshoe tears (9), and giant tear or dialysis (4)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29662301/conventional-trabeculectomy-versus-trabeculectomy-with-the-ex-press-%C3%A2-mini-glaucoma-shunt-differences-in-postoperative-interventions
#6
Naoki Tojo, Mitsuya Otsuka, Atsushi Hayashi
Purpose: To compare the postoperative interventions and outcomes between conventional trabeculectomy and trabeculectomy with the Ex-PRESS® mini-glaucoma shunt device (Ex-Press). Methods: This was a retrospective, comparative, single-facility study. We analyzed the cases of 108 glaucoma patients who underwent trabeculectomy and were followed for >1 year. Thirty-nine eyes underwent a conventional trabeculectomy (conventional group) and 69 eyes underwent a trabeculectomy with an Ex-Press (Ex-Press group)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29662300/the-effects-of-repeated-ozurdex-injections-on-ocular-hypertension
#7
Sepehr Bahadorani, Chelsey Krambeer, Kendall Wannamaker, Wayne Tie, Michael Jansen, Jason Espitia, Jeong-Hyeon Sohn, Michael A Singer
Purpose: The purpose of this study was to correlate the degree of ocular hypertension with the number of Ozurdex injections. Methods: Intraocular pressure (IOP) fluctuations for a total of 183 injections were studied over a period of at least 12 months. The main indications for treatment were uveitis, diabetic macular edema, and retinal vein occlusion. Results: Results of the study demonstrate that repeated Ozurdex injections do not increase the frequency of IOP spikes beyond 30 mmHg...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29662299/clinical-characteristics-and-causes-of-visual-impairment-in-a-low-vision-clinic-in-northern-jordan
#8
May M Bakkar, Eman A Alzghoul, Mera F Haddad
Aim: The aim of the study was to identify causes of visual impairment among patients attending a low vision clinic in the north of Jordan and to study the relevant demographic characteristics of these patients. Subjects and methods: The retrospective study was conducted through a review of clinical records of 135 patients who attended a low vision clinic in Irbid. Clinical characteristics of the patients were collected, including age, gender, primary cause of low vision, best corrected visual acuity, and current prescribed low vision aids...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29662298/anti-vegf-treatment-of-macular-edema-associated-with-retinal-vein-occlusion-patterns-of-use-and-effectiveness-in-clinical-practice-echo-study-report-2
#9
J Michael Jumper, Pravin U Dugel, Sanford Chen, Kevin J Blinder, John G Walt
Purpose: To evaluate the efficacy, safety, and injection frequency of vascular endothelial growth factor (VEGF) antagonists in the treatment of macular edema secondary to retinal vein occlusion (RVO) in clinical practice. Patients and methods: A multicenter retrospective study of the medical records of 165 patients (95 branch RVO, 70 central RVO) treated with at least three anti-VEGF injections in the study eye was conducted. Available data collected for at least 6 months after the first injection included Snellen best-corrected visual acuity (BCVA), central retinal thickness (CRT) by time-domain optical coherence tomography (TD-OCT) or spectral-domain optical coherence tomography (SD-OCT), anti-VEGF injections, other treatments/procedures for RVO, and adverse events...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29636597/comparison-of-simulated-keratometric-changes-following-wavefront-guided-and-wavefront-optimized-myopic-laser-assisted-in-situ-keratomileusis
#10
Wen-Shin Lee, Edward E Manche
Purpose: The aim of the study was to determine and compare the relationship between change in simulated keratometry (K) and degree of refractive correction in wavefront-guided (WFG) and wavefront-optimized (WFO) myopic laser-assisted in situ keratomileusis (LASIK). Methods: A total of 51 patients were prospectively randomized to WFG LASIK in one eye and WFO LASIK in the contralateral eye at the Byers Eye Institute, Stanford University. Changes in simulated K and refractive error were determined at 1 year post-operatively...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29636596/comparison-of-macular-thickness-by-optical-coherence-tomography-measurements-after-uneventful-phacoemulsification-using-ketorolac-tromethamine-nepafenac-vs-a-control-group-preoperatively-and-postoperatively
#11
Ricardo Alexandre Stock, Daiane Karen Galvan, Rafael Godoy, Elcio Luiz Bonamigo
Purpose: To analyze, using optical coherence tomography, the macular thickness values of patient groups using nonsteroidal anti-inflammatory drug (NSAID) eye drops or artificial tears during uncomplicated cataract surgery. Methods: A total of 77 eyes from 42 patients were analyzed. The patients were divided into three groups, each using one of the following ophthalmic sterile suspensions: nepafenac (21 eyes), propylene glycol (24 eyes), or ketorolac tromethamine (32 eyes)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29636595/visual-acuity-endothelial-cell-density-and-polymegathism-after-iris-fixated-lens-implantation
#12
Nader Nassiri, Saeedeh Ghorbanhosseini, Ebrahim Jafarzadehpur, Sara Kavousnezhad, Nariman Nassiri, Kourosh Sheibani
Purpose: The purpose of this study was to evaluate the visual acuity as well as endothelial cell density (ECD) and polymegathism after iris-fixated lens (Artiflex® AC 401) implantation for correction of moderate to high myopia. Patients and methods: In this retrospective cross-sectional study, 55 eyes from 29 patients undergoing iris-fixated lens implantation for correction of myopia (-5.00 to -15.00 D) from 2007 to 2014 were evaluated. Uncorrected visual acuity, best spectacle-corrected visual acuity, refraction, ECD and polymegathism (coefficient of variation [CV] in the sizes of endothelial cells) were measured preoperatively and 6 months postoperatively...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29636594/ranibizumab-treatment-history-as-predictor-of-the-switch-response-to-aflibercept-evidence-for-drug-tolerance
#13
Ali Dirani, Irmela Mantel
Purpose: To investigate whether tolerance to the anti-VEGF drug, ranibizumab, develops after drug exposure and to determine whether the history of treatment with ranibizumab prior to refractoriness can predict the post-switching responses to aflibercept. Methods: We retrospectively investigated neovascular age-related macular degeneration patients refractory to ranibizumab (intra- or subretinal fluid despite monthly injections for ≥6 months) who were switched to aflibercept and were followed up for at least 12 months on each of ranibizumab and aflibercept...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29628756/combination-of-ranibizumab-and-indomethacin-for-neovascular-age-related-macular-degeneration-randomized-controlled-trial
#14
Andrea Russo, Nicolò Scaroni, Elena Gambicorti, Raffaele Turano, Francesco Morescalchi, Ciro Costagliola, Francesco Semeraro
Purpose: The aim of this study was to evaluate whether indomethacin eye drops and intravitreal ranibizumab (IVR) injections would provide additional benefit over ranibizumab alone in the treatment of choroidal neovascularization (CNV). Participants and methods: This was a randomized, prospective pilot study of eyes with new-onset CNV. Fifty-eight patients were randomized 1:1 into a ranibizumab monotherapy (RM) group and a ranibizumab plus indomethacin (RI) group...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29615834/corneal-clarity-measurements-in-patients-with-keratoconus-undergoing-either-penetrating-or-deep-anterior-lamellar-keratoplasty
#15
Khaled Alzahrani, Syarifah-Faiza Dardin, Fiona Carley, Arun Brahma, Debbie Morley, M Chantal Hillarby
Purpose: To compare the corneal clarity measurement between penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK) in patients with keratoconus, using densitometry software for the Oculus Pentacam. Methods: A retrospective comparative study was carried out at Manchester Royal Eye Hospital. Data were collected 12-18 months after corneal transplantation for keratoconus, including postoperative corneal densitometry, best corrected visual acuity (BCVA), central corneal thickness (CCT), and other relevant clinical details...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29615833/patient-and-physician-perspectives-on-the-use-of-cyclosporine-ophthalmic-emulsion-0-05-for-the-management-of-chronic-dry-eye
#16
REVIEW
Tatiana Deveney, Penny A Asbell
Dry eye disease (DED) is a multifactorial disease of the ocular surface and is one of the most common reasons for patients to visit an eye care provider. Cyclosporine A (CsA) is an immune modulating drug that was approved in the US for topical use in the treatment of DED in 2003, which led to a paradigm change in our understanding and treatment of DED, turning attention to control of inflammation for treatment. This review summarizes the literature to date regarding the impact of CsA on the treatment of DED...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29615832/prevalence-and-risk-factors-of-diabetic-retinopathy-among-an-elderly-population-with-diabetes-in-nepal-the-bhaktapur-retina-study
#17
Raba Thapa, Shankha N Twyana, Govinda Paudyal, Shankar Khanal, Ruth van Nispen, Stevie Tan, Suman S Thapa, Ghmb van Rens
Aim: Diabetic retinopathy (DR) is an emerging cause of blindness in developing countries. This study aimed to explore the prevalence and risk factors of DR in an elderly population in Nepal. Subjects and methods: This is a population-based, cross-sectional study. A total of 1860 subjects at the age 60 years and above participated (response rate 88.6%). A detailed history was obtained, presenting and best-corrected visual acuity were measured, and anterior segment and posterior segment examinations were carried out...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29606853/the-role-of-corneal-hysteresis-during-the-evaluation-of-patients-with-possible-normal-tension-glaucoma
#18
Ming Chen, Laura Kueny, Arthur L Schwartz
Purpose: There are multiple reports of the role of corneal hysteresis (CH) as an independent risk factor for the diagnosis and risk of progression of normal-tension glaucoma (NTG). Our study measured CH with the Ocular Response Analyzer (ORA) in patients with intraocular pressure (IOP) <21 mmHg to investigate if a low CH would identify NTG in this Asian-based practice. Methods: This was a prospective cross-sectional study of patients who underwent routine eye examination during 2016 in a private practice in Honolulu, Hawaii, where most patients are Asian...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29606852/switching-from-concomitant-therapy-to-tafluprost-timolol-fixed-combination
#19
Kenji Inoue, Taku Kawashima, Seiki Katakura, Kyoko Shidara, Takayuki Fujimoto, Hiromi Kohmoto, Minako Shiokawa, Ryo Moriyama, Ryoko Okayama
Purpose: To evaluate the efficacy and safety of tafluprost/timolol fixed combination (TTFC). Study design: A prospective clinical study. Methods: Twenty-eight patients (28 eyes) with primary open-angle glaucoma, who had used tafluprost and timolol gel for at least 3 months with good adherence, were enrolled. Concomitant administration of tafluprost and timolol was switched to TTFC without a washout period. The intraocular pressure (IOP), blood pressure, pulse rate, and ocular signs were compared between before switching (baseline), and 4 and 8 weeks after switching...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29593379/the-clinical-effectiveness-of-tafluprost-on-japanese-normal-tension-glaucoma-patients
#20
Akio Nomura, Hirotaka Osaki, Fumiki Shimada, Yasuaki Kuwayama
Purpose: This study evaluates the effect of tafluprost on visual field progression in normal-tension glaucoma (NTG) in a Japanese population under daily clinical practice settings. Patients and methods: This is a post-marketing, multicenter, non-interventional, observational study. Patients with NTG who initiated tafluprost treatment were registered and prospectively observed for 2-3 years to investigate its effectiveness on visual field progression and intraocular pressure (IOP) and safety in Japan...
2018: Clinical Ophthalmology
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