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Early Intervention in Psychiatry

Martina Papmeyer, Jacqueline Aston, Judith Everts-Graber, Ulrike Heitz, Erich Studerus, Stefan J Borgwardt, Rolf-Dieter Stieglitz, Anita Riecher-Rössler
BACKGROUND: We aimed to determine the prognostic accuracy of the Basel Screening Instrument for Psychosis (BSIP) in terms of specificity, sensitivity, positive and negative predictive value by following up individuals that were initially not considered to be at increased risk of psychosis based on the BSIP. Moreover, clinical characteristics of these individuals were examined given the relative lack of such information in the literature. METHODS: As part of the "Früherkennung von Psychosen" (FePsy) study, 87 individuals were screened with the BSIP...
April 21, 2017: Early Intervention in Psychiatry
Angela Nicholas, Erin Holloway, Nic Telford, Debra Rickwood
AIMS: The primary aim of this pilot study was to determine the psychometric properties of the 18-item headspace Family and Friends Satisfaction Scale (hFAFSS). METHODS: During August 2015, staff from 22 headspace centres approached family members and friends of young people attending headspace to complete the hFAFSS. Principal components analysis with oblique Promin rotation and polychoric correlations were used to assess the factor structure of the hFAFSS. RESULTS: There were 277 usable responses...
April 19, 2017: Early Intervention in Psychiatry
Helle Karkov Madsen, Dorte Nordholm, Kristine Krakauer, Lasse Randers, Merete Nordentoft
AIM: To make a thorough characterization of the co-morbidity, psychopathology and demographics in the first Danish ultra high-risk (UHR) sample. METHOD: Forty-two UHR subjects went through comprehensive interviews assessing their psychopathology, psychiatric disorders, substance use and family history of psychiatric disorders. RESULTS: All UHR subjects met the criteria of at least 1 axis I diagnosis in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) and met on average four diagnoses (both axis I and II), mostly within the areas of depression, anxiety and substance abuse...
April 19, 2017: Early Intervention in Psychiatry
Avra Selick, Janet Durbin, Nhi Vu, Karen O'Connor, Tiziana Volpe, Elizabeth Lin
Family support is a core component of the Early Psychosis Intervention (EPI) model, yet it continues to have relatively low rates of implementation in practice. This paper reports results of a literature review on facilitators and barriers to delivering family interventions in EPI programmes. A search was conducted of 4 electronic databases, Medline, EMBASE, PsycINFO and Joanna Briggs, from 2000 to 2015 using terms related to early onset psychosis, family work and implementation. Four thousand four hundred and two unique studies were identified, 7 of which met inclusion criteria...
April 18, 2017: Early Intervention in Psychiatry
Ruchika Gajwani, Michael Larkin, Chris Jackson
BACKGROUND: Lifetime risk of suicide in first-episode psychosis far exceeds the general population, with the risk of suicide persisting long after first presentation. There is strong evidence to suggest that women more frequently attempt suicide, while men are at a greater risk of completing suicide. First-hand experiential evidence is needed in order to better understand men's motives for, and struggles with, suicidality in early psychosis. METHODS: Semi-structured interviews were conducted with 7 participants...
April 18, 2017: Early Intervention in Psychiatry
Anastasia Theodoridou, Michael P Hengartner, Karsten Heekeren, Diane Dvorsky, Frauke Schultze-Lutter, Miriam Gerstenberg, Susanne Walitza, Wulf Rössler
AIM: Presentation of attenuated positive psychotic symptoms (APS) was reported to be modestly influenced by age, sex and education in a psychosis-risk sample. We re-examined the influence of demographic variables on APS in an independent psychosis-risk sample. METHOD: In a clinical high-risk-sample (N = 188; 13-35 years; 60.1% men), bivariate correlations were examined with Spearman correlations. All other associations were computed with generalized linear models...
April 18, 2017: Early Intervention in Psychiatry
Cindy B Woolverton, Emily K Bell, Aubrey M Moe, Patricia Harrison-Monroe, Nicholas J K Breitborde
BACKGROUND: Social functioning deficits greatly affect individuals with psychotic disorders resulting in decreased ability to maintain relationships, jobs and pursuit of educational goals. Deficits in social cognition have been hypothesized to be an important contributor to these deficits in social functioning. In particular, 5 domains of social cognition have been suggested to be relevant in the study of psychotic disorders: (1) attributional style, (2) emotion recognition, (3) social knowledge, (4) social perception and (5) theory of mind...
April 12, 2017: Early Intervention in Psychiatry
Shamima Saloojee, Jonathan K Burns, Ayesha A Motala
BACKGROUND: To determine the prevalence and incidence of metabolic syndrome in individuals with a first episode of severe mental illness from South Africa. METHODS: Antipsychotic naïve study subjects with a first episode of severe mental illness and control subjects were recruited at baseline for a prospective study. Individuals without metabolic syndrome at baseline were followed up for 12 months after antipsychotic medication was initiated. Metabolic syndrome was determined at baseline and at the 12-month follow-up using the Joint Interim Statement criteria...
April 12, 2017: Early Intervention in Psychiatry
Frank Hughes, Lisa Hebel, Paul Badcock, Alexandra G Parker
AIMS: Guiding principles are arguably central to the development of any health service. The aim of this article is to report on the outcomes of a youth mental health (YMH) community of practice (CoP), which identified a range of guiding principles that provide a clear point of comparison for the only other set of principles for YMH service delivery proposed to date. METHODS: A YMH CoP was established in 2010 as part of the Victorian State Government approach to improving YMH care...
April 12, 2017: Early Intervention in Psychiatry
Ben Chen, Haishan Shi, Le Hou, Xiaomei Zhong, Yanhua Wang, Zhangying Wu, Qi Peng, Dong Zheng, Yuefen Zhang, Yan Tan, Ziyan Fang, Xinru Chen, Xinni Luo, Sha Liu, Ning Yuping
BACKGROUND: The effect of penicillin therapy on clinical outcomes vary among patients with general paresis (GP). We sought to explore biomarkers that might serve as predictors of clinical outcomes in GP and identify patients requiring early intervention. METHODS: Thirty-five inpatients with GP were recruited. Each GP patient underwent comprehensive neuropsychological, neuroimaging and laboratory assessments before receiving penicillin therapy, and returned for follow-up evaluations after 6 months...
April 5, 2017: Early Intervention in Psychiatry
Gagan Fervaha, Hiroyoshi Takeuchi, George Foussias, Margaret K Hahn, Ofer Agid, Gary Remington
BACKGROUND: Individuals with schizophrenia engage in goal-directed activities significantly less often compared to healthy individuals in the community. There is ample evidence documenting the presence of motivational deficits in schizophrenia using observer-based ratings; however, purely self-reported accounts of patients' motivation are less well understood. This study examined subjective accounts of trait achievement motivation among relatively young, clinically stable, early-course outpatients with schizophrenia...
February 23, 2017: Early Intervention in Psychiatry
Jo Davison, Jan Scott
BACKGROUND: Studies of potential interventions for asymptomatic individuals at risk of severe mental disorders (ie, clinical stage 0) have focused on genetic counselling or the views of adults with established disease. No study has interviewed youth at risk of bipolar disorders (BD). METHODS: Qualitative analysis of interviews with asymptomatic adolescent offspring of adults with BD (OSBD = 7) and unrelated parents with bipolar disorders (PBD = 6) to examine manifest and latent themes in the dialogue...
February 11, 2017: Early Intervention in Psychiatry
Sarah E Hetrick, Denise A O'Connor, Heather Stavely, Frank Hughes, Kerryn Pennell, Eoin Killackey, Patrick D McGorry
AIM: Our aim was to develop an implementation guide that was informed by an analysis of context-specific barriers and enablers, behaviour change theory, as well as evidence about the effects of implementation interventions, for the establishment and scaling up of an early intervention model for psychosis (called Early Psychosis Prevention and Intervention Centre (EPPIC)). METHODS: We used a systematic approach involving four steps. First, the target behaviours of the EPPIC model for implementation were specified...
February 8, 2017: Early Intervention in Psychiatry
Aswin Ratheesh, Susan M Cotton, Christopher G Davey, Sophie Adams, Andreas Bechdolf, Craig Macneil, Michael Berk, Patrick D McGorry
AIM: Early intervention and prevention of serious mental disorders such as bipolar disorder has the promise of decreasing the burden associated with these disorders. With increasing early and preventive intervention efforts among cohorts such as those with a familial risk for bipolar disorder, there is a need to examine the associated ethical concerns. The aim of this review was to examine the ethical issues underpinning the clinical research on pre-onset identification and preventive interventions for bipolar disorder...
April 2017: Early Intervention in Psychiatry
Sarah K Liddle, Frank P Deane, Stewart A Vella
AIM: Mental health is a major concern among adolescents. Most mental illnesses have their onset during this period, and around 14% of all young people aged 12 to 17 years experience a mental illness in a 12-month period. However, only 65% of these adolescents access health services to address their mental health problems. Approximately 70% of all Australian adolescents participate in sport, and this presents an opportunity for mental health promotion. METHODS: This paper reviewed current approaches by sporting organizations to mental health promotion, prevention and early intervention by searching peak body websites, as well as the wider Internet...
April 2017: Early Intervention in Psychiatry
Marita Pruessner, Kia Faridi, Jai Shah, Mark Rabinovitch, Srividya Iyer, Sherezad Abadi, Nicole Pawliuk, Ridha Joober, Ashok K Malla
AIM: In the context of an increasing focus on indicated prevention of psychotic disorders, we describe the operation of the Clinic for Assessment of Youth at Risk (CAYR) over 10 years, a specialized service for identification, monitoring and treatment of young individuals who meet ultra-high risk (UHR) criteria for psychosis, and its integration within the Prevention and Early Intervention Program for Psychosis (PEPP) in Montreal, Canada. METHODS: We outline rationale, development, inclusion and exclusion criteria, assessment, services offered, community outreach and liaison with potential referral sites, and our research focus on risk and protective factors related to the neural diathesis-stress model of psychosis...
April 2017: Early Intervention in Psychiatry
Maija Lindgren, Marko Manninen, Hely Kalska, Ulla Mustonen, Taina Laajasalo, Kari Moilanen, Matti O Huttunen, Tyrone D Cannon, Sebastian Therman, Jaana Suvisaari
AIM: We explored whether cognitive performance, and verbal learning in particular, predicts psychosis or psychiatric hospitalizations among unselected first-admission adolescent patients in general psychiatric care. METHODS: Up to 152 adolescents aged 15-18 were interviewed with the SIPS, tested with a cognitive test battery in the beginning of their psychiatric treatment, and followed for a maximum of 9 years (median 4.5 years). RESULTS: The composite factors of processing speed, verbal performance and visuospatial performance did not predict psychosis (n = 7) or all-cause psychiatric hospitalizations (n = 26) beyond psychosis risk symptoms...
April 2017: Early Intervention in Psychiatry
Anika Maraj, Kelly K Anderson, Nina Flora, Manuela Ferrari, Suzanne Archie, Kwame J McKenzie
AIM: To assess variability in symptom presentation and explanatory models of psychosis for people from different ethnic groups. METHODS: Clients with first-episode psychosis (n = 171) who identified as black African, black Caribbean or white European were recruited from early intervention programmes in Toronto and Hamilton. We compared results by ethnic group for symptom profiles and explanatory models of illness. RESULTS: Clients of black Caribbean origin had a lower odds of reporting that they were speaking incomprehensibly (OR = 0...
April 2017: Early Intervention in Psychiatry
Maude Schneider, Martial Van der Linden, Sarah Menghetti, Martin Debbané, Stephan Eliez
AIMS: 22q11.2 deletion syndrome (22q11.2DS) is a neurogenetic condition associated with an increased risk of developing schizophrenia. Previous studies have shown that negative symptoms represent the most specific clinical characteristic of psychosis in 22q11.2DS and are strongly associated with outcome. However, the psychological mechanisms associated with these symptoms in this population are poorly understood. In accordance with recent conceptualizations in the field of schizophrenia, the present study aims at investigating whether negative symptoms are associated with the presence of negative performance beliefs and cognitive deficits...
April 2017: Early Intervention in Psychiatry
Mareike Kommescher, Sonja Gross, Verena Pützfeld, Joachim Klosterkötter, Andreas Bechdolf
AIM: The concept of coping is central to recent models of psychosis. The aim of the present paper is to explore whether specific coping styles relate to certain stages of the disorder. METHODS: Thirty-nine clients at clinical high risk (CHR) of first-episode psychosis, 19 clients with first-episode psychosis and 52 clients with multiple-episode psychosis completed a Stress Coping Questionnaire. This questionnaire consists of 114 items defining one overall positive coping scale (with three subscales) and one negative coping scale...
April 2017: Early Intervention in Psychiatry
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