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Early Intervention in Psychiatry

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https://www.readbyqxmd.com/read/27860281/counting-up-the-risks-how-common-are-risk-factors-for-morbidity-and-mortality-in-young-people-with-psychosis
#1
Lisa Anne Hahn, Andrew Mackinnon, Debra L Foley, Vera A Morgan, Anna Waterreus, Gerald F Watts, David J Castle, Dennis Liu, Cherrie A Galletly
BACKGROUND: This study examined the prevalence of risk factors for cardiovascular (CV)-related morbidity and mortality in young people with psychosis aged 18 to 24 years. METHODS: The study included 132 people aged 18 to 24 years who participated in the 2010 second Australian national survey of people living with psychosis. The 2009 World Health Organisation (WHO) Global Health Risks report was used as a framework to determine which specific risk factors were present in each in these young people...
November 17, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27863046/early-psychosis-intervention-outpatient-service-of-the-1st-psychiatric-university-clinic-in-athens-3-years-of-experience
#2
Constantinos Kollias, Lida-Alkisti Xenaki, Stefanos Dimitrakopoulos, Ioannis Kosteletos, Vassilis Kontaxakis, Nikos Stefanis, Charalampos Papageorgiou
To present the 3-year experience of the early intervention in psychosis (EIP) service implementation of the 1st Psychiatric University Clinic in Athens. An overview of: (1) the purpose of our service, (2) the referral network, (3) the selection criteria, (4) the diagnostic procedures, (5) the therapeutic interventions and (6) the research activities. The service was established in 2012 and developed gradually aiming to provide information, early detection, treatment and support to people aged 15 to 40 years with psychotic manifestations, who are either at increased risk of developing psychosis (at-risk mental state [ARMS]) or with first episode psychosis (FEP)...
November 9, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27863039/family-member-engagement-with-early-psychosis-specialty-care
#3
Alicia Lucksted, Jennifer Stevenson, Ilana Nossel, Amy Drapalski, Sarah Piscitelli, Lisa B Dixon
BACKGROUND: Family members of individuals with early psychosis (EP) play critical roles in their engagement with EP services, but family member experiences of those roles are insufficiently understood. METHODS: We conducted semi-structured interviews with 18 family members of individuals enrolled in EP services during the Recovery After an Initial Schizophrenia Episode-Implementation Evaluation Study (RAISE-IES study), to better understand their experiences engaging with EP specialty care and their roles in client engagement in services...
November 9, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27860369/factor-structure-of-therapist-fidelity-to-individual-resiliency-training-in-the-recovery-after-an-initial-schizophrenia-episode-early-treatment-program
#4
Julia Browne, Alexandra N Edwards, David L Penn, Piper S Meyer-Kalos, Jennifer D Gottlieb, Paul Julian, Kelsey Ludwig, Kim T Mueser, John M Kane
BACKGROUND: Evidence-based approaches and early intervention have improved the long-term prognosis of individuals with schizophrenia. However, little is known about the therapeutic processes involved in individual therapy in first-episode psychosis. A comprehensive psychosocial/psychiatric programme for this population, NAVIGATE, includes an individual therapy component, individual resiliency training (IRT). Fidelity of clinicians' adherence to the IRT protocol has been collected to ensure proper implementation of this manual-based intervention...
November 9, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27860294/screening-for-psychosis-risk-among-adolescents-in-child-and-adolescent-mental-health-services-a-description-of-the-first-step-with-the-16-item-version-of-the-prodromal-questionnaire-pq-16
#5
Yvonne de Jong, Cornelis L Mulder, Albert E Boon, Mathijs Deen, Maarten van 't Hof, Mark van der Gaag
AIM: Although the 16-item version of the Prodromal Questionnaire (PQ-16) is used as a screener in the early detection of psychosis risk, little is known about PQ-16 scores among adolescents referred to the Child and Adolescent Mental Health Services. We assessed such scores in adolescents referred to these services in the Netherlands, and also their associations with age, gender, diagnosis and level of functioning. METHODS: The PQ-16 was added to regular intake procedures...
November 9, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27734591/the-relapse-rate-and-predictors-of-relapse-in-patients-with-first-episode-psychosis-following-discontinuation-of-antipsychotic-medication
#6
Suzanne Di Capite, Rachel Upthegrove, Pavan Mallikarjun
BACKGROUND: To determine the "real world" relapse rate in patients with first-episode psychosis (FEP) who had discontinued antipsychotic medication and identify socio-demographic and clinical factors associated with the risk of relapse. METHODS: Quantitative data were obtained via case-note review on 63 patients with FEP who had discontinued antipsychotic medication from Birmingham Early Intervention Service between 2012 and 2015. The follow-up period was until either: an occurrence of a relapse; end of 12-month study period; end of patient's case-note record...
October 13, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27731949/predictors-of-functioning-in-people-suffering-from-first-episode-psychosis-1%C3%A2-year-into-entering-early-intervention-service-in-hong-kong
#7
Catherine Shiu-Yin Chong, Man-Wah Siu, Condy Hoi-Shuen Kwan, Wing-Chung Chang, Edwin Ho-Ming Lee, Sherry Kit-Wa Chan, Christy Lai-Ming Hui, Fiona Yee-Ki Tam, Eric Yu-Hai Chen, William Tak-Lam Lo
AIM: To explore the changes of functioning in people suffering from first-episode psychosis throughout their first year into an early intervention service, and the baseline predictors of their functioning levels at baseline, 6 and 12 months METHOD: Consecutive subjects presenting to an early intervention service were recruited from 1 February 2013 to 31 May 2015. Information on their socio-demographic status was collected. Structured instruments were used to assess their premorbid functioning, duration of untreated psychosis, psychopathology and insight at baseline...
October 12, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27726284/first-episode-psychosis-ongoing-mental-health-service-utilization-during-the-stable-period-for-adolescents
#8
Robin E Gearing, Kathryne B Brewer, Irfan Mian, Kiara Moore, Prudence Fisher, Jane Hamilton, James Mandiberg
AIM: The timely identification and treatment of psychosis are increasingly the focus of early interventions, with research targeting the initial high-risk period in the months following first-episode hospitalization. Ongoing treatment after stabilization is also essential in the years following a first-episode psychosis (FEP), but has received less research attention. In this study, variables that could impact continued psychiatric service utilization by adolescents following their FEP and temporal patterns in service utilization are examined...
October 11, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27696760/integrating-family-work-into-the-treatment-of-young-people-with-severe-and-complex-depression-a-developmentally-focused-model
#9
Simon Rice, Stephen Halperin, Simon Blaikie, Katherine Monson, Rachel Stefaniak, Mark Phelan, Christopher Davey
AIM: Although models of family intervention are clearly articulated in the child and early adolescent literature, there is less clarity regarding family intervention approaches in later adolescence and emerging adulthood. METHODS: This study provides the rationale and intervention framework for a developmentally sensitive model of time-limited family work in the outpatient treatment of complex youth depression (15-25 years). RESULTS: Derived from current practice in the Youth Mood Clinic (YMC) at Orygen Youth Health, Melbourne, a stepped model of family intervention is discussed...
October 2, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27684654/premorbid-adjustment-in-individuals-at-ultra-high-risk-for-developing-psychosis-a-case-control-study
#10
Anders L Dannevang, Lasse Randers, Matthias Gondan, Kristine Krakauer, Dorte Nordholm, Merete Nordentoft
AIM: Deterioration in premorbid adjustment is related to ultra-high risk (UHR) individuals developing psychosis, but it has not been examined how UHR individuals' development differs compared to healthy controls. This study investigates differences in premorbid adjustment between UHR individuals and a healthy control group. METHOD: A total of 48 UHR individuals and 50 healthy controls matched on group level for age, gender and parents' socio-economic status were included in the study...
September 29, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27677625/the-c-jaad-a-french-team-for-early-intervention-in-psychosis-in-paris
#11
Alice Oppetit, Julie Bourgin, Gilles Martinez, Mathilde Kazes, Célia Mam-Lam-Fook, Raphael Gaillard, Jean-Pierre Olié, Marie-Odile Krebs
AIM: The aim is to describe a centre operating in Paris that pioneers the early intervention for young people at the onset and at high risk of psychosis in France. METHODS: Comprehensive descriptive analysis of different clinical and service measures is used in describing the implementation of the C'JAAD (Evaluation Centre for Young Adults and Adolescents) using data from an ongoing prospective non-interventional research programme. RESULTS: Over a 2-year period, 151 patients were referred to the C'JAAD and included in the ICAAR research programme...
September 28, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27653624/a-study-on-negative-and-depressive-symptom-prevalence-in-individuals-at-ultra-high-risk-for-psychosis
#12
Marleine Azar, Marita Pruessner, Lawrence H Baer, Srividya Iyer, Ashok K Malla, Martin Lepage
BACKGROUND: Negative symptoms are known to be present in the prodromal stage of psychotic disorders, yet little is known about their prevalence. Studies examining the presence of negative symptoms in ultra-high risk (UHR) populations have shown some limitations, notably failing to control depression. The objective of this study was to examine the prevalence of negative symptoms in the presence of significant levels of depression and in the absence of such symptoms (primary negative symptoms) over 1 year and to examine differences in negative symptoms in psychosis converters and non-converters...
September 21, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27629407/gene-environment-interaction-between-the-brain-derived-neurotrophic-factor-val66met-polymorphism-psychosocial-stress-and-dietary-intake-in-early-psychosis
#13
Giulia Gattere, Alexander Stojanovic-Pérez, Rosa Monseny, Lourdes Martorell, Laura Ortega, Itziar Montalvo, Montse Solé, María José Algora, Ángel Cabezas, Rebecca M Reynolds, Elisabet Vilella, Javier Labad
AIM: The brain-derived neurotrophic factor (BDNF) is a major participant in the regulation of food intake and may play a role in the regulation of the stress response. We aimed to investigate whether there is a gene-environment interaction in the relationship between stress and BDNF Val66Met polymorphism in relation to dietary patterns in a sample of subjects with early psychosis. METHODS: We studied 124 early psychotic disorder (PD) patients, 36 At-Risk Mental States (ARMS) and 62 healthy subjects (HS)...
September 15, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27629273/examining-the-durability-of-a-hybrid-remote-and-computer-based-cognitive-remediation-intervention-for-adolescents-with-22q11-2-deletion-syndrome
#14
Margaret A Mariano, Kerri Tang, Matthew Kurtz, Wendy R Kates
AIM: Schizophrenia and 22q11.2 deletion syndrome (22q11DS) share similar patterns of cognitive deficits. Up to 30% of those with 22q11DS develop schizophrenia during early adulthood. As cognitive decline has recently been found to predict onset of psychosis in adolescents with 22q11DS, early interventions such as cognitive remediation (CR) during adolescence are warranted. This paper investigates the durability of a remote, computerized, CR programme for youth with 22q11DS. Our aim was to determine if the positive effects of CR persisted 6 months beyond intervention completion...
September 15, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27621217/characterization-of-white-matter-abnormalities-in-early-stage-schizophrenia
#15
Tom A Hummer, Michael M Francis, Jenifer L Vohs, Emily Liffick, Nicole F Mehdiyoun, Alan Breier
AIM: White matter abnormalities have been reported in schizophrenia and may indicate altered cortical network integrity and structural connectivity, which have been hypothesized as key pathophysiological components of this illness. In this study, we aimed to further characterize the nature and progression of white matter alterations during the early stages of the disorder. METHODS: We employed diffusion tensor imaging (DTI) approaches to investigate fractional anisotropy (FA), radial diffusivity (RD) and axial diffusivity (AD) in 40 patients with schizophrenia and related psychotic disorders (aged 18-30 years) who were within 5 years of illness, along with an age-, sex- and race-matched sample of 21 healthy controls...
September 13, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27619198/the-freed-project-first-episode-and-rapid-early-intervention-in-eating-disorders-service-model-feasibility-and-acceptability
#16
Amy Brown, Jessica McClelland, Elena Boysen, Victoria Mountford, Danielle Glennon, Ulrike Schmidt
AIM: Eating disorders (EDs) are disabling disorders, predominantly affecting adolescents and young adults. Untreated symptoms have lasting effects on brain, body and behaviour. Care pathway-related barriers often prevent early detection and treatment of ED. The aim of this study was to assess the feasibility and acceptability of FREED (First Episode and Rapid Early Intervention for Eating Disorder), a novel service for young people (aged 18-25 years) with recent ED onset (≤3 years), embedded in a specialist adult National Health Service ED service...
September 13, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27619055/search-for-protective-factors-for-psychosis-a-population-based-sample-with-special-interest-in-unaffected-individuals-with-parental-psychosis
#17
Emmi Keskinen, Riikka Marttila, Heli Koivumaa-Honkanen, Kristiina Moilanen, Sirkka Keinänen-Kiukaanniemi, Markku Timonen, Matti Isohanni, John McGrath, Jouko Miettunen, Erika Jääskeläinen
AIM: To find factors that are associated with not having psychotic illness in a prospective general population sample, with a special interest in individuals with parental psychosis. METHODS: Data from the Northern Finland Birth Cohort 1966 (n = 10 458) and several registers were used to detect individuals with and without parental psychosis. Altogether, 594 persons had parent(s) with psychosis and 48 of them also had psychosis subsequently. Variables related to pregnancy and birth, family and childhood, health and habits in adolescence, school performance and physical activity were studied to identify determinants of unaffected status among individuals with and without parental psychosis...
September 13, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/27618789/early-detection-and-integrated-care-for-adolescents-and-young-adults-with-severe-psychotic-disorders-rationales-and-design-of-the-integrated-care-in-early-psychosis-study-access-iii
#18
Martin Lambert, Daniel Schöttle, Mary Sengutta, Friederike Ruppelt, Anja Rohenkohl, Daniel Luedecke, Luise Antonia Nawara, Britta Galling, Anne-Lena Falk, Linus Wittmann, Vivien Niehaus, Gizem Sarikaya, Ute Handwerk, Wiebke Rothländer, Liz Rietschel, Charlotte Gagern, Benjamin Lange, Christina Meigel-Schleiff, Dieter Naber, Michael Schulte-Markwort, Helmut Krüger, Hans-Peter Unger, Sven Sippel, Sabine Ott, Georg Romer, Anne Daubmann, Karl Wegscheider, Christoph U Correll, Benno G Schimmelmann, Thomas Bock, Jürgen Gallinat, Anne Karow
AIM: The Integrated Care in Early Psychosis (ACCESS III) Study examined the efficacy and cost-effectiveness of a combined intervention consisting of strategies to improve early detection and quality of care (integrated care including therapeutic assertive community treatment) in adolescents and young adults in the early phase of a severe psychotic disorder from 2011 to 2014. METHODS: This is a prospective, single-centre, 1-year cohort study comparing an intervention condition (early detection plus integrated care, n = 120) to the historical control condition (standard care, SC, n = 105) for adolescents and young adults aged 12-29 years suffering from a severe, early-phase psychotic disorder (i...
September 12, 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/26486257/the-common-elements-of-treatment-engagement-for-clinically-high-risk-youth-and-youth-with-first-episode-psychosis
#19
Kimberly D Becker, Sara L Buckingham, Leslie Rith-Najarian, Emily R Kline
AIM: Without treatment, clinically high-risk (CHR) youth or youth with first-episode psychosis (FEP) have increased risk for significant complications from their illness; yet, treatment engagement among these youth is critically low. The purpose of this study was to examine engagement efforts with CHR/FEP youth to stimulate new ideas that might facilitate participation in services for this population. METHODS: A literature review using distillation methods identified engagement practices reported in two bodies of literature...
December 2016: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/26362703/early-intervention-services-in-psychosis-from-evidence-to-wide-implementation
#20
Claudio Csillag, Merete Nordentoft, Masafumi Mizuno, Peter B Jones, Eóin Killackey, Matthew Taylor, Eric Chen, John Kane, David McDaid
AIM: Early intervention (EI) in psychosis is a comprehensive and evidence-based approach aimed at detection and treatment of psychotic symptoms in their early stages. This paper presents core features and noteworthy aspects of the evidence basis and limitations of EI, the importance of programme fidelity, challenges for its widespread dissemination and economic perspectives related to it. METHODS: This paper is a narrative review about the evidence supporting EI and the challenges to its widespread dissemination...
December 2016: Early Intervention in Psychiatry
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