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Early Intervention in Psychiatry

Ahmad Hajebi, Homayoun Amini, Leila Kashani, Vandad Sharifi
BACKGROUND: To assess the clinical course and outcome of patients with methamphetamine-induced psychosis in comparison with patients with primary psychotic disorders. METHODS: This prospective study was conducted on patients with methamphetamine-induced psychosis, and 2 groups of primary psychotic disorders: affective psychosis and non-affective psychosis admitted to 2 psychiatric hospitals in Tehran, Iran, with a first episode of a psychotic illness. A total of 165 subjects (55 in each group) were selected using convenience sampling...
December 19, 2016: Early Intervention in Psychiatry
Lisa Anne Hahn, Andrew Mackinnon, Debra L Foley, Vera A Morgan, Anna Waterreus, Gerald F Watts, David J Castle, Dennis Liu, Cherrie A Galletly
BACKGROUND: This study examined the prevalence of risk factors for cardiovascular (CV)-related morbidity and mortality in young people with psychosis aged 18 to 24 years. METHODS: The study included 132 people aged 18 to 24 years who participated in the 2010 second Australian national survey of people living with psychosis. The 2009 World Health Organisation (WHO) Global Health Risks report was used as a framework to determine which specific risk factors were present in each in these young people...
November 17, 2016: Early Intervention in Psychiatry
Constantinos Kollias, Lida-Alkisti Xenaki, Stefanos Dimitrakopoulos, Ioannis Kosteletos, Vassilis Kontaxakis, Nikos Stefanis, Charalampos Papageorgiou
To present the 3-year experience of the early intervention in psychosis (EIP) service implementation of the 1st Psychiatric University Clinic in Athens. An overview of: (1) the purpose of our service, (2) the referral network, (3) the selection criteria, (4) the diagnostic procedures, (5) the therapeutic interventions and (6) the research activities. The service was established in 2012 and developed gradually aiming to provide information, early detection, treatment and support to people aged 15 to 40 years with psychotic manifestations, who are either at increased risk of developing psychosis (at-risk mental state [ARMS]) or with first episode psychosis (FEP)...
November 9, 2016: Early Intervention in Psychiatry
Alicia Lucksted, Jennifer Stevenson, Ilana Nossel, Amy Drapalski, Sarah Piscitelli, Lisa B Dixon
BACKGROUND: Family members of individuals with early psychosis (EP) play critical roles in their engagement with EP services, but family member experiences of those roles are insufficiently understood. METHODS: We conducted semi-structured interviews with 18 family members of individuals enrolled in EP services during the Recovery After an Initial Schizophrenia Episode-Implementation Evaluation Study (RAISE-IES study), to better understand their experiences engaging with EP specialty care and their roles in client engagement in services...
November 9, 2016: Early Intervention in Psychiatry
Julia Browne, Alexandra N Edwards, David L Penn, Piper S Meyer-Kalos, Jennifer D Gottlieb, Paul Julian, Kelsey Ludwig, Kim T Mueser, John M Kane
BACKGROUND: Evidence-based approaches and early intervention have improved the long-term prognosis of individuals with schizophrenia. However, little is known about the therapeutic processes involved in individual therapy in first-episode psychosis. A comprehensive psychosocial/psychiatric programme for this population, NAVIGATE, includes an individual therapy component, individual resiliency training (IRT). Fidelity of clinicians' adherence to the IRT protocol has been collected to ensure proper implementation of this manual-based intervention...
November 9, 2016: Early Intervention in Psychiatry
Yvonne de Jong, Cornelis L Mulder, Albert E Boon, Mathijs Deen, Maarten van 't Hof, Mark van der Gaag
AIM: Although the 16-item version of the Prodromal Questionnaire (PQ-16) is used as a screener in the early detection of psychosis risk, little is known about PQ-16 scores among adolescents referred to the Child and Adolescent Mental Health Services. We assessed such scores in adolescents referred to these services in the Netherlands, and also their associations with age, gender, diagnosis and level of functioning. METHODS: The PQ-16 was added to regular intake procedures...
November 9, 2016: Early Intervention in Psychiatry
Caragh Behan, Sarah Masterson, Mary Clarke
AIM: Although early intervention in psychosis is an accepted policy internationally, the evidence base for this paradigm, originates mostly from the specialist model. In a real world setting, variations of this model are often implemented. The aim of this paper is to systematically evaluate the evidence for delivering early intervention outside the specialist stand-alone centre. METHODS: A systematic search following the PRISMA guidelines was undertaken in Medline, PsycInfo, Embase and the Cochrane trials register...
February 2017: Early Intervention in Psychiatry
Ann K Shinn, Kirsten W Bolton, Rakesh Karmacharya, Kathryn E Lewandowski, Cagri Yuksel, Justin T Baker, Virginie-Anne Chouinard, Samira M Pingali, Hilary Bye, Katherine Cederbaum, Dost Öngür
AIMS: Most programs specializing in the treatment of first-episode psychosis in the United States focus on schizophrenia. However, many early psychosis patients do not fit into this diagnostic category. Here we describe McLean OnTrack, an intensive outpatient treatment program that accepts all comers with first-episode psychosis. METHODS: We assessed baseline characteristics of patients in the 2.5 years since program initiation. We examined how initial referral diagnoses compare with current diagnoses, calculating the proportion of diagnostic changes...
February 2017: Early Intervention in Psychiatry
Alfonso González-Valderrama, Carmen Paz Castañeda, Cristián Mena, Juan Undurraga, Pilar Mondaca, Matías Yañez, Paula Bedregal, Ruben Nachar
AIM: To determine the association between duration of untreated psychosis (DUP) and symptoms remission in a hospitalized first-episode psychosis cohort. METHODS: Inpatients with a first-episode non-affective psychosis were recruited. Subjects were divided into two groups of long and short DUP using a 3-month cut-off point, and this was related to remission at 10 weeks of treatment. Multivariate analyses were performed. RESULTS: Fifty-five inpatients were included...
February 2017: Early Intervention in Psychiatry
Amal Abdel-Baki, Shalini Lal, Olivier D-Charron, Emmanuel Stip, Nadjia Kara
AIM: Computers, video games and technological devices are part of young people's everyday lives. However, their use in first-episode psychosis (FEP) treatment is rare. The purpose of this study was to better understand the access and use of technology among individuals with FEP, including gaming activities, to inform future development of technology-enabled therapeutic applications. METHODS: Self-administered survey on use of technological tools in 71 FEP individuals...
February 2017: Early Intervention in Psychiatry
Nicholas Peiper, Robert J Illback, Aileen O'Reilly, Richard Clayton
AIM: Significant overlap and comorbidity has been demonstrated among young people with mental health problems. This paper examined demographic characteristics, heterogeneity of need descriptors and services provided among young people (12-25 years) engaging in brief interventions at Jigsaw in the Republic of Ireland. METHOD: Between 1 January 2013 and 31 December 2013, a total of 2571 young people sought help from 1 of 10 Jigsaw sites. Of these, 1247 engaged in goal-focused brief interventions, typically consisting of one to six face-to-face sessions...
February 2017: Early Intervention in Psychiatry
Luyken H Stouten, Wim Veling, Winfried Laan, Mischa van der Helm, Mark van der Gaag
AIM: Most studies on the determinants of psychosocial functioning in first-episode psychosis used few predictors. This study examines the effects of multiple cognitive domains and multiple symptoms on psychosocial functioning. METHODS: A total of 162 patients with a first-episode psychosis were assessed within 3 months after referral to an early psychosis treatment department. Four psychopathological subdomains (positive and negative symptoms, depression and anxiety) and five subdomains of psychosocial functioning (work/study, relationships, self-care, disturbing behaviour and general psychosocial functioning) were measured...
February 2017: Early Intervention in Psychiatry
John Lyne, Ridha Joober, Norbert Schmitz, Martin Lepage, Ashok Malla
AIM: Duration of untreated psychosis (DUP) has been associated with negative symptoms in several studies; however, longitudinal findings have been inconsistent. No previous study has accounted for active psychosis after presentation, although this could impact on outcomes in a manner similar to DUP. METHODS: We measured Scale for the Assessment of Positive Symptoms at frequent intervals during the 12 months after initial presentation to determine the active psychosis duration for 230 individuals with first-episode psychosis...
February 2017: Early Intervention in Psychiatry
Fatemeh Abdollahi, Mehran Zarghami, Shariff-Ghazali Sazlina, Munn-Sann Lye
AIM: Prolonged depression during the post-partum period is associated with maternal and infant mortality and morbidity. Less attention has been given to factors that predict the persistence of depression beyond the first 3 months post-partum. METHODS: From a longitudinal cohort of 2279 women who attended Mazandaran's primary health centres in 2009, 478 women with an Edinburgh Postnatal Depression Scale (EPDS) score of 12 or greater in the third trimester of pregnancy were recruited...
February 2017: Early Intervention in Psychiatry
Hanan Al Fayez, Julia Lappin, Robin Murray, Jane Boydell
AIM: Recent studies of 'duration of untreated psychosis' (DUP) indicate that some patients remain untreated in the community for some time. Considerable emphasis has been placed on reducing the DUP. However, most studies investigating DUP have been conducted in Western countries, where well-developed primary care systems are available. This study aims to describe DUP and its association with both demographic factors and pathways to care in Riyadh, Saudi Arabia. METHODS: A retrospective study of 421 new case records of all Saudi schizophrenia patients over a 2-year period in six governmental hospitals in Riyadh, Saudi Arabia...
February 2017: Early Intervention in Psychiatry
Ivy F Tso, Stephan F Taylor, Tyler B Grove, Tara Niendam, Steven Adelsheim, Andrea Auther, Barbara Cornblatt, Cameron S Carter, Roderick Calkins, J Daniel Ragland, Tamara Sale, William R McFarlane
AIM: The Scale of Prodromal Symptoms (SOPS) was developed to identify individuals experiencing early signs of psychosis, a critical first step towards early intervention. Preliminary dimension reduction analyses suggested that psychosis-risk symptoms may deviate from the traditional symptom structure of schizophrenia, but findings have been inconsistent. This study investigated the phenomenology of psychosis risk symptoms in a large sample from a multi-site, national study using rigorous factor analysis procedure...
February 2017: Early Intervention in Psychiatry
Kimberly D Becker, Sara L Buckingham, Leslie Rith-Najarian, Emily R Kline
AIM: Without treatment, clinically high-risk (CHR) youth or youth with first-episode psychosis (FEP) have increased risk for significant complications from their illness; yet, treatment engagement among these youth is critically low. The purpose of this study was to examine engagement efforts with CHR/FEP youth to stimulate new ideas that might facilitate participation in services for this population. METHODS: A literature review using distillation methods identified engagement practices reported in two bodies of literature...
December 2016: Early Intervention in Psychiatry
Claudio Csillag, Merete Nordentoft, Masafumi Mizuno, Peter B Jones, Eóin Killackey, Matthew Taylor, Eric Chen, John Kane, David McDaid
AIM: Early intervention (EI) in psychosis is a comprehensive and evidence-based approach aimed at detection and treatment of psychotic symptoms in their early stages. This paper presents core features and noteworthy aspects of the evidence basis and limitations of EI, the importance of programme fidelity, challenges for its widespread dissemination and economic perspectives related to it. METHODS: This paper is a narrative review about the evidence supporting EI and the challenges to its widespread dissemination...
December 2016: Early Intervention in Psychiatry
Leslie Marino, Lawrence S Wissow, Maryann Davis, Michael T Abrams, Lisa B Dixon, Eric P Slade
AIM: To assess demographic and clinical predictors of outpatient mental health clinic follow-up after inpatient psychiatric hospitalization among Medicaid-enrolled young adults. METHODS: Using logistic regression and administrative claims data from the Maryland public mental health system and Maryland Medicaid for young adults ages 18-26 who were enrolled in Medicaid (N = 1127), the likelihood of outpatient mental health follow-up within 30 days after inpatient psychiatric hospitalization was estimated ...
December 2016: Early Intervention in Psychiatry
Suzanne Di Capite, Rachel Upthegrove, Pavan Mallikarjun
BACKGROUND: To determine the "real world" relapse rate in patients with first-episode psychosis (FEP) who had discontinued antipsychotic medication and identify socio-demographic and clinical factors associated with the risk of relapse. METHODS: Quantitative data were obtained via case-note review on 63 patients with FEP who had discontinued antipsychotic medication from Birmingham Early Intervention Service between 2012 and 2015. The follow-up period was until either: an occurrence of a relapse; end of 12-month study period; end of patient's case-note record...
October 13, 2016: Early Intervention in Psychiatry
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