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Early Intervention in Psychiatry

Jo Davison, Jan Scott
BACKGROUND: Studies of potential interventions for asymptomatic individuals at risk of severe mental disorders (ie, clinical stage 0) have focused on genetic counselling or the views of adults with established disease. No study has interviewed youth at risk of bipolar disorders (BD). METHODS: Qualitative analysis of interviews with asymptomatic adolescent offspring of adults with BD (OSBD = 7) and unrelated parents with bipolar disorders (PBD = 6) to examine manifest and latent themes in the dialogue...
February 11, 2017: Early Intervention in Psychiatry
Sarah E Hetrick, Denise A O'Connor, Heather Stavely, Frank Hughes, Kerryn Pennell, Eoin Killackey, Patrick D McGorry
AIM: Our aim was to develop an implementation guide that was informed by an analysis of context-specific barriers and enablers, behaviour change theory, as well as evidence about the effects of implementation interventions, for the establishment and scaling up of an early intervention model for psychosis (called Early Psychosis Prevention and Intervention Centre (EPPIC)). METHODS: We used a systematic approach involving four steps. First, the target behaviours of the EPPIC model for implementation were specified...
February 8, 2017: Early Intervention in Psychiatry
Shruthi Venkataraman, Gerald Jordan, Megan A Pope, Srividya N Iyer
AIM: To better understand cultural competence in early intervention for psychosis, we compared service users' and service providers' perceptions of the importance of providers being culturally competent and attentive to aspects of culture. METHODS: At a Canadian early intervention programme, a validated scale was adapted to assess service user (N = 51) and provider (N = 30) perceptions of service providers' cultural competence and the importance accorded thereto...
January 26, 2017: Early Intervention in Psychiatry
Anna Ärmänen, Marius Lahti, Sebastian Therman, Jaana Suvisaari, Maija Lindgren
AIM: Recent evidence from psychosis risk studies of preselected samples suggests that early functional impairment may be a vulnerability marker for psychosis. We investigated whether functional impairment predicted later risk of psychotic disorder and psychiatric hospitalizations in adolescents at entry to general psychiatric services. METHODS: A total of 154 adolescents, aged 15 to 18 years, were recruited to the study at entry to general adolescent psychiatric services in Helsinki, Finland...
January 26, 2017: Early Intervention in Psychiatry
Matthew J Taylor, Tania Blanco Pena, Rocio Perez-Iglesias
AIM: Prognosis following early psychosis is highly variable. Long-term prognostic information from research studies is available in only a few areas. We sought to understand how well routine discharge information allows prediction of long-term readmission prognosis. METHODS: We reviewed the records of 239 people leaving Early Intervention services, after an average of 2.5 years, and counted the number of relapses. The distribution was modelled and extrapolated to a predicted 10 year outcome...
January 26, 2017: Early Intervention in Psychiatry
Laura Giusti, Donatella Ussorio, Anna Salza, Maurizio Malavolta, Annalisa Aggio, Valeria Bianchini, Massimo Casacchia, Rita Roncone
BACKGROUND: People with anxiety disorders tend to focus on unpleasant and threatening stimuli. Our aims were to evaluate: (1) the presence of paranoid ideation, and the jumping to conclusions (JTC) bias in young suffering from an anxiety disorder and (2) the effectiveness of a cognitive-behavioural intervention (CBT) to manage anxiety combined with 2 modules to reduce the JTC bias. METHODS: Psychopathology, social functioning, metacognition and the JTC bias were investigated in 60 subjects, randomly assigned to the experimental CBT group + treatment-as-usual (TAU) (n = 35) or to a wait-list group (n = 25) receiving only TAU...
January 26, 2017: Early Intervention in Psychiatry
Rowena Jones, Luke Banbury
BACKGROUND: There is a growing body of research looking into the high rates of victimization amongst people with severe mental illness. Studies to date have tended to look at victimization rates in people with chronic mental illness over a wide age range. However, national crime surveys indicate that younger people are more likely to be the victim of crime than older people. There is also evidence that people from ethnic minorities are more likely to experience and less likely to report criminal victimization...
January 26, 2017: Early Intervention in Psychiatry
Nicholas J K Breitborde, Aubrey M Moe, Cindy Woolverton, Patricia Harrison-Monroe, Emily K Bell
Growing evidence suggests that specialized, multi-component treatment programmes produce improvements in numerous outcomes among individuals with first-episode psychosis. However, these programmes often lack interventions specifically designed to address deficits in social cognition. This raises questions about the effectiveness of such programmes in addressing deficits in social cognition that accompany psychotic disorders. We investigated the effect of participation in a multi-component treatment programme on social cognition among 71 individuals with first-episode psychosis...
January 25, 2017: Early Intervention in Psychiatry
Marie Sutton, Donal O'Keeffe, Timothy Frawley, Kevin Madigan, Felicity Fanning, Elizabeth Lawlor, Eric Roche, Aine Kelly, Niall Turner, Arielle Horenstein, Eadbhard O'Callaghan, Mary Clarke
The aim of this study was to assess the feasibility of a psychosis information intervention for professionals in contact with young people in Ireland. A quasi-experimental pre- and post-intervention design was used. One thousand and thirty-two professionals received an information intervention designed to improve mental health literacy (MHL) and confidence in providing help to people with psychosis. Seven hundred and fifty-five participants completed the Psychosis Information and Confidence Questionnaire pre- and post-intervention...
January 19, 2017: Early Intervention in Psychiatry
Ahmad Hajebi, Homayoun Amini, Leila Kashani, Vandad Sharifi
BACKGROUND: To assess the clinical course and outcome of patients with methamphetamine-induced psychosis in comparison with patients with primary psychotic disorders. METHODS: This prospective study was conducted on patients with methamphetamine-induced psychosis, and 2 groups of primary psychotic disorders: affective psychosis and non-affective psychosis admitted to 2 psychiatric hospitals in Tehran, Iran, with a first episode of a psychotic illness. A total of 165 subjects (55 in each group) were selected using convenience sampling...
December 19, 2016: Early Intervention in Psychiatry
Caragh Behan, Sarah Masterson, Mary Clarke
AIM: Although early intervention in psychosis is an accepted policy internationally, the evidence base for this paradigm, originates mostly from the specialist model. In a real world setting, variations of this model are often implemented. The aim of this paper is to systematically evaluate the evidence for delivering early intervention outside the specialist stand-alone centre. METHODS: A systematic search following the PRISMA guidelines was undertaken in Medline, PsycInfo, Embase and the Cochrane trials register...
February 2017: Early Intervention in Psychiatry
Ann K Shinn, Kirsten W Bolton, Rakesh Karmacharya, Kathryn E Lewandowski, Cagri Yuksel, Justin T Baker, Virginie-Anne Chouinard, Samira M Pingali, Hilary Bye, Katherine Cederbaum, Dost Öngür
AIMS: Most programs specializing in the treatment of first-episode psychosis in the United States focus on schizophrenia. However, many early psychosis patients do not fit into this diagnostic category. Here we describe McLean OnTrack, an intensive outpatient treatment program that accepts all comers with first-episode psychosis. METHODS: We assessed baseline characteristics of patients in the 2.5 years since program initiation. We examined how initial referral diagnoses compare with current diagnoses, calculating the proportion of diagnostic changes...
February 2017: Early Intervention in Psychiatry
Alfonso González-Valderrama, Carmen Paz Castañeda, Cristián Mena, Juan Undurraga, Pilar Mondaca, Matías Yañez, Paula Bedregal, Ruben Nachar
AIM: To determine the association between duration of untreated psychosis (DUP) and symptoms remission in a hospitalized first-episode psychosis cohort. METHODS: Inpatients with a first-episode non-affective psychosis were recruited. Subjects were divided into two groups of long and short DUP using a 3-month cut-off point, and this was related to remission at 10 weeks of treatment. Multivariate analyses were performed. RESULTS: Fifty-five inpatients were included...
February 2017: Early Intervention in Psychiatry
Amal Abdel-Baki, Shalini Lal, Olivier D-Charron, Emmanuel Stip, Nadjia Kara
AIM: Computers, video games and technological devices are part of young people's everyday lives. However, their use in first-episode psychosis (FEP) treatment is rare. The purpose of this study was to better understand the access and use of technology among individuals with FEP, including gaming activities, to inform future development of technology-enabled therapeutic applications. METHODS: Self-administered survey on use of technological tools in 71 FEP individuals...
February 2017: Early Intervention in Psychiatry
Nicholas Peiper, Robert J Illback, Aileen O'Reilly, Richard Clayton
AIM: Significant overlap and comorbidity has been demonstrated among young people with mental health problems. This paper examined demographic characteristics, heterogeneity of need descriptors and services provided among young people (12-25 years) engaging in brief interventions at Jigsaw in the Republic of Ireland. METHOD: Between 1 January 2013 and 31 December 2013, a total of 2571 young people sought help from 1 of 10 Jigsaw sites. Of these, 1247 engaged in goal-focused brief interventions, typically consisting of one to six face-to-face sessions...
February 2017: Early Intervention in Psychiatry
Luyken H Stouten, Wim Veling, Winfried Laan, Mischa van der Helm, Mark van der Gaag
AIM: Most studies on the determinants of psychosocial functioning in first-episode psychosis used few predictors. This study examines the effects of multiple cognitive domains and multiple symptoms on psychosocial functioning. METHODS: A total of 162 patients with a first-episode psychosis were assessed within 3 months after referral to an early psychosis treatment department. Four psychopathological subdomains (positive and negative symptoms, depression and anxiety) and five subdomains of psychosocial functioning (work/study, relationships, self-care, disturbing behaviour and general psychosocial functioning) were measured...
February 2017: Early Intervention in Psychiatry
John Lyne, Ridha Joober, Norbert Schmitz, Martin Lepage, Ashok Malla
AIM: Duration of untreated psychosis (DUP) has been associated with negative symptoms in several studies; however, longitudinal findings have been inconsistent. No previous study has accounted for active psychosis after presentation, although this could impact on outcomes in a manner similar to DUP. METHODS: We measured Scale for the Assessment of Positive Symptoms at frequent intervals during the 12 months after initial presentation to determine the active psychosis duration for 230 individuals with first-episode psychosis...
February 2017: Early Intervention in Psychiatry
Fatemeh Abdollahi, Mehran Zarghami, Shariff-Ghazali Sazlina, Munn-Sann Lye
AIM: Prolonged depression during the post-partum period is associated with maternal and infant mortality and morbidity. Less attention has been given to factors that predict the persistence of depression beyond the first 3 months post-partum. METHODS: From a longitudinal cohort of 2279 women who attended Mazandaran's primary health centres in 2009, 478 women with an Edinburgh Postnatal Depression Scale (EPDS) score of 12 or greater in the third trimester of pregnancy were recruited...
February 2017: Early Intervention in Psychiatry
Hanan Al Fayez, Julia Lappin, Robin Murray, Jane Boydell
AIM: Recent studies of 'duration of untreated psychosis' (DUP) indicate that some patients remain untreated in the community for some time. Considerable emphasis has been placed on reducing the DUP. However, most studies investigating DUP have been conducted in Western countries, where well-developed primary care systems are available. This study aims to describe DUP and its association with both demographic factors and pathways to care in Riyadh, Saudi Arabia. METHODS: A retrospective study of 421 new case records of all Saudi schizophrenia patients over a 2-year period in six governmental hospitals in Riyadh, Saudi Arabia...
February 2017: Early Intervention in Psychiatry
Ivy F Tso, Stephan F Taylor, Tyler B Grove, Tara Niendam, Steven Adelsheim, Andrea Auther, Barbara Cornblatt, Cameron S Carter, Roderick Calkins, J Daniel Ragland, Tamara Sale, William R McFarlane
AIM: The Scale of Prodromal Symptoms (SOPS) was developed to identify individuals experiencing early signs of psychosis, a critical first step towards early intervention. Preliminary dimension reduction analyses suggested that psychosis-risk symptoms may deviate from the traditional symptom structure of schizophrenia, but findings have been inconsistent. This study investigated the phenomenology of psychosis risk symptoms in a large sample from a multi-site, national study using rigorous factor analysis procedure...
February 2017: Early Intervention in Psychiatry
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