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Archives of Osteoporosis

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https://www.readbyqxmd.com/read/30413893/cost-effectiveness-of-a-home-safety-intervention-to-prevent-falls-in-impaired-elderly-people-living-in-the-community
#1
Christopher Kunigkeit, Stephanie Stock, Dirk Müller
PURPOSE: Among others, the German National Prevention Conference recently recommended the provision of preventive options for elderly to maintain their independent living. Because a home safety assessment and modification program (HSM) has shown to be effective in avoiding falls and risk of falling in elderly, the aim of this analysis was to evaluate the cost-effectiveness of HSM in patients aged ≥ 80 years who receive non-institutionalized long-term care. METHODS: In order to reflect quality-adjusted life years (QALYs) and costs resulting from HSM, a Markov-model with a time horizon of 20 years was performed from the perspective of the German statutory health insurance (SHI) and statutory long-term care insurance (LCI)...
November 9, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30406425/osteoporosis-in-postmenopausal-women-in-this-decade-a-bibliometric-assessment-of-current-research-and-future-hotspots
#2
REVIEW
Yuanyu Qiu, Wu Yang, Qijin Wang, Sijia Yan, Bo Li, Xiao Zhai
Postmenopausal osteoporosis (PMOP) has already become a major public health problem. However, there was no bibliometric analysis estimating the evolutionary process of PMOP research. PURPOSE: This study aimed to assess its scientific activity. METHODS: Publications on PMOP were retrieved from Science Citation Index-Expanded (SCI-E) of the Web of Science (WoS) from 2008 to 2018. VOSviewer software was used for data mining and visualization. The quantity of papers, number of citations, citation frequency per year, and H-index were assessed and compared among different countries, institutes, and researchers...
November 7, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30397843/individualized-evaluation-of-lumbar-bone-mineral-density-in-children-with-cerebral-palsy
#3
Ibrahim Duran, J Katzmann, K Martakis, C Stark, O Semler, E Schoenau
Lumbar spine bone mineral density (LS-BMD) assessed by dual-energy X-ray absorptiometry (DXA) is used in children with cerebral palsy (CP) to evaluate bone health. LS-BMD results in children with CP are influenced significantly by their height, BMI, and mobility level. An adjustment for these parameters might improve the clinical significance of the method. PURPOSE/INTRODUCTION: DXA evaluation is considered useful in children with CP to assess bone health. For this purpose, LS-BMD is often used...
November 5, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30397732/changes-in-bone-mineral-density-in-women-before-critical-illness-a-matched-control-nested-cohort-study
#4
Neil R Orford, Michael Bailey, Rinaldo Bellomo, Julie A Pasco, David J Cooper, Mark A Kotowicz
The contribution of premorbid bone health to accelerated bone loss following critical illness is unknown. This study compared bone density in women before critical illness to women who did not become critically ill. Overall bone density was similar, although femoral neck bone mass increased immediately prior to critical illness. PURPOSE: The relative contribution of acute and chronic factors to accelerated loss of bone mineral density (BMD) following critical illness is unknown. This study compared the BMD trajectory of women before critical illness to the BMD trajectory of women who did not become critically ill...
November 5, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30382424/a-brief-history-of-frax
#5
REVIEW
John A Kanis, Helena Johansson, Nicholas C Harvey, Eugene V McCloskey
This paper reviews the research programme that went into the development of FRAX® and its impact in the 10 years since its release in 2008. INTRODUCTION: Osteoporosis is defined on the measurement of bone mineral density though the clinical consequence is fracture. The sensitivity of bone mineral density measurements for fracture prediction is low, leading to the development of FRAX to better calculate the likelihood of fracture and target anti-osteoporosis treatments. METHODS: The method used in this paper is literature review...
October 31, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30374788/individualized-evaluation-of-lumbar-bone-mineral-density-and-bone-mineral-apparent-density-in-children-and-adolescents
#6
Ibrahim Duran, K Martakis, M Rehberg, O Semler, E Schoenau
Lumbar spine bone mineral density (LS-BMD) assessed by dual-energy X-ray absorptiometry (DXA) is used in children to evaluate bone health. LS-BMD results in children are influenced significantly by height and BMI. An adjustment for these parameters may improve the clinical use of the method. PURPOSE/INTRODUCTION: DXA evaluation is considered useful in children to assess bone health. For this purpose, lumbar spine bone mineral density (LS-BMD) and bone mineral apparent density (LS-BMAD) are often used...
October 29, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30374781/judicious-use-of-dxa-bmd-in-assessing-fracture-risk-by-using-clinical-risk-factors-in-the-indian-population
#7
Beena Bansal, Ambrish Mithal, Shweta Rebecca Chopra, Shubhda Bhanot, M Shafi Kuchay, Khalid J Farooqui
FRAX scores were significantly higher in patients admitted with fragility fractures than controls and can be useful in choosing the right patients for bone density testing, thus using of an expensive test judiciously. PURPOSE: This study was planned to compare the FRAX scores for the risk for major osteoporotic fracture (FRAX-MOF) and hip fracture (FRAX-HF) in patients with fragility fractures (cases) and those admitted for other indications (controls) in the orthopedic ward in our institute...
October 29, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30374631/long-term-effects-of-inhaled-corticosteroids-on-bone-mineral-density-in-older-women-with-asthma-or-copd-a-registry-based-cohort-study
#8
Wenjia Chen, Kate M Johnson, J Mark FitzGerald, Mohsen Sadatsafavi, William D Leslie
We assessed the association between long-term inhaled corticosteroid (ICS) use and bone mineral density (BMD) in older women with chronic respiratory disease. Women with > 50% adherence to ICS use had very slightly accelerated BMD loss at the total hip compared with those with lower or ICS use. INTRODUCTION: This study evaluated the impact of long-term ICS therapy on bone loss in older women with asthma or chronic obstructive pulmonary disease (COPD). METHODS: We used a population-based bone densitometry registry linked with administrative health data covering the province of Manitoba, Canada (1999-2013), to identify women aged > 40 years who had diagnosed asthma or COPD...
October 29, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30353299/calcitriol-treatment-in-patients-with-low-vitamin-d-levels
#9
Refik Tanakol, Nurdan Gül, Ayşe Kubat Üzüm, Ferihan Aral
The aim of the the study is to compare the effects of cholecalciferol and calcitriol on bone mineral metabolism in women with vitamin D deficiency. Calcitriol was associated with a significant increase in bone mineral density at the lumbar spine in patients with low vitamin D levels. PURPOSE/INTRODUCTION: Active vitamin D analogs may have larger impact in decreasing bone loss and fracture rate compared to cholecalciferol in osteoporosis. However, their effects in the treatment of vitamin D deficiency compared to cholecalciferol are not clear...
October 23, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30341636/impact-of-bisphosphonate-compliance-on-the-risk-of-osteoporotic-fracture-in-france
#10
Manon Belhassen, Bernard Cortet, Cyrille B Confavreux, Liliane Lamezec, Marine Ginoux, Eric Van Ganse
Limited information is available on the impact of bisphosphonate compliance levels on fracture risk in osteoporosis patients in France. The results of this nested case-control, retrospective study suggest that fracture risk did not significantly change with bisphosphonate compliance levels, except for highly compliant patients. PURPOSE/INTRODUCTION: This was the first study conducted in France to evaluate the impact of compliance levels for bisphosphonates, the most frequently prescribed first-line anti-osteoporotic treatment, on fracture risk...
October 19, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30334129/association-between-polycyclic-aromatic-hydrocarbons-and-osteoporosis-data-from-nhanes-2005-2014
#11
Wenhou Duan, Xin Meng, Yanxin Sun, Chongqi Jia
The association between osteoporosis and polycyclic aromatic hydrocarbons was not clear. However, recent studies showed that both osteoporosis and polycyclic aromatic hydrocarbons were associated with reactive oxygen species. So we presumed that polycyclic aromatic hydrocarbons were associated with increased odds of osteoporosis. We found 3-hydroxyfluorene was associated with decreased odds of osteoporosis, while 2-hydroxyfluorene was associated with increased odds of osteoporosis. PURPOSE: Previous studies showed that polycyclic aromatic hydrocarbons were involved in the production of reactive oxygen species that played an important role in illness...
October 17, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30324335/serum-25-hydroxyvitamin-d-status-quantitative-ultrasound-parameters-and-their-determinants-in-greek-population
#12
Effimia V Grigoriou, George Trovas, Nikolaos Papaioannou, Polyzois Makras, Panagiotis Kokkoris, Ismene Dontas, Konstantinos Makris, Symeon Tournis, George V Dedoussis
Vitamin D deficiency and quantitative ultrasound measurements are associated with bone fragility. We assessed these parameters and their correlates. 87.7% of the population has vitamin D inadequacy and this correlated with lifestyle factors. These results contribute to epidemiological data needed for population guidelines for bone health. PURPOSE: Vitamin D deficiency and quantitative ultrasound (QUS) parameters are among the most important clinical risk factors of bone fragility. Few data are available for Greek population...
October 15, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30324242/improvement-in-the-primary-and-secondary-prevention-of-osteoporosis-by-a-fracture-liaison-service-feedback-from-a-single-french-center-care-pathway
#13
Arthur Vrignaud, Simon Pelletier, Emmanuelle Dernis, Yvon Moui, Bénédicte Haettich
Osteoporosis is responsible for fragility fractures, thus causing significant morbidity and mortality. This study shows that care pathways, such as Le Mans General Hospital Fracture Liaison Service, are useful and efficient in improving the prevention of osteoporosis and of its consequences. INTRODUCTION: Osteoporosis is a major public health concern, causing significant morbidity and mortality. Care pathways, called Fracture Liaison Services, have demonstrated their utility in preventing osteoporosis-associated morbidity and mortality...
October 15, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30306385/longitudinal-determinants-of-12-month-changes-on-bone-health-in-adolescent-male-athletes
#14
Esther Ubago-Guisado, Dimitris Vlachopoulos, Ioannis G Fatouros, Chariklia K Deli, Diamanda Leontsini, Luis A Moreno, Daniel Courteix, Luis Gracia-Marco
We identified the determinants of 12-month changes of areal bone mineral density (aBMD), hip geometry and trabecular bone score (TBS) in adolescent male athletes. Changes in region-specific lean mass and the type of sport are the most consistent determinants in this population. PURPOSE: This study aims to identify the determinants of 12-month changes of areal bone mineral density (aBMD), hip geometry and trabecular bone score (TBS) in adolescent male athletes. METHODS: The sample was 104 adolescent males aged 12-14 years at baseline that were followed over 12 months: 39 swimmers, 37 footballers (or soccer players) and 28 cyclists...
October 10, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30306345/prevention-of-low-bone-mass-to-achieve-high-bone-density-in-mexico-position-of-the-mexican-association-for-bone-and-mineral-metabolism
#15
Rolando Espinosa, Patricia Clark, Edgar Denova-Gutiérrez, María de Los Ángeles Aguilera-Barreiro, Mario Flores, Pilar Diez, Salomón Jasqui, María Del Pilar De la Peña, Federico Cisneros-Dreinhofer, Pilar Lavielle, Víctor Mercado
In Mexico, osteoporosis is a public health problem. In this document, the Mexican Association for Bone and Mineral Metabolism defines its position on calcium, vitamin D supplement use, and physical activity as an effective, safe, and cost-effective initiatives to prevent low bone mass. INTRODUCTION: In Mexico, osteoporosis is a public health problem that is expected to increase in the decades ahead. Generally, modifiable risk factors for bone health are related with lifestyles, especially nutrition and physical activity...
October 10, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30306279/association-of-high-density-lipoprotein-triglycerides-and-homocysteine-with-bone-mineral-density-in-young-indian-tribal-women
#16
Rucha Saoji, Rajat Subra Das, Meena Desai, Achhelal Pasi, Geetanjali Sachdeva, Tapan Kumar Das, M Ikram Khatkhatay
This study investigated association between lipids and homocysteine (Hcy) with bone mineral density (BMD) in young women as opposed to previous studies on elderly women. HDL, triglyceride, and Hcy are significantly associated with BMD in young women and tobacco and alcohol consumption have no effect on this association. PURPOSE: The present study investigates whether the association of serum lipids and homocysteine (Hcy) with bone mineral density (BMD) reported mostly in elderly population can be generalized to young or premenopausal women, consequently suggesting screening of young women with low BMD for dyslipidemia or any cardiovascular events and vice versa...
October 10, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30306272/prevalence-of-vitamin-d-deficiency-in-postmenopausal-high-and-low-energy-fracture-patient
#17
Jun Seung Lee, Ji Wan Kim
This study evaluated the prevalence of vitamin D deficiency in postmenopausal women with fractures and revealed a high prevalence of vitamin D deficiency regardless of whether the injury mechanism was high or low energy. However, the prescription rate of vitamin D supplementation was lower in the high-energy compared to the low-energy injury group. PURPOSE: The present study aimed to investigate the prevalence of vitamin D deficiency in postmenopausal women with fractures from low-energy and high-energy injuries and to determine differences in the prevalence of vitamin D deficiency and the rate of postoperative vitamin D supplementation between the two groups...
October 10, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30306268/effects-of-anti-osteoporosis-medications-on-total-hip-arthroplasty-risks-in-osteoporotic-patients-with-hip-osteoarthritis-in-taiwan-a-nationwide-cohort-study
#18
Chih-Chien Hung, Chen-Yu Wang, Shau-Huai Fu, Rong-Sen Yang, Fei-Yuan Hsiao
This nationwide cohort study examined the potential disease-modifying effect of anti-osteoporosis medication on hip osteoarthritis. The results revealed that the usage of anti-osteoporosis medication is not associated with decreased risk in undergoing total hip arthroplasty in patient with hip osteoarthritis. PURPOSE: This study aimed to assess the association between use of anti-osteoporosis medications (AOMs) and the risk of undergoing total hip arthroplasty (THA) in patients with hip osteoarthritis (OA)...
October 10, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30293145/plain-radiograghs-of-lumbar-spine-in-patients-with-low-back-pain
#19
Ngozi R Njeze, Salome N Ezeofor, Olanike R Agwu-Umahi
Low back pain (LBP) is a common presenting complaint in our hospital in Enugu Nigeria. Three hundred thirty-three radiographs of patients with LBP were studied. A lot of them had bony outgrowths (osteophytes) on the spine. Plain radiograph of the spine is useful in studying these patients' condition. INTRODUCTION: Low back pain (LBP) is one of the common symptoms which bring patients to hospital and ultimately to radiology department for medical assistance. Plain radiographs of lumbar spine are usually the initial imaging tools requested by clinicians...
October 7, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/30267162/the-prevalence-of-overtreatment-of-osteoporosis-results-from-the-paadrn-trial
#20
Sylvie F Hall, Nicole C Wright, Fredric D Wolinsky, Yiyue Lou, Stephanie Edmonds, Douglas Roblin, Michael Jones, Kenneth Saag, Peter Cram
Overtreatment of osteoporosis increases costs and puts patients at unnecessary risk of experiencing adverse drug events. In the Patient Activation After DXA Receipt Notification (PAADRN) trial, we found that 8% of individuals with no indication for therapy were recommended a new osteoporosis medication or continuation of an existing medication. PURPOSE: There is a robust body of literature addressing undertreatment in osteoporosis, but limited data addressing overtreatment. Understanding overtreatment is important to minimize harm and decrease costs...
September 28, 2018: Archives of Osteoporosis
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