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Archives of Osteoporosis

R Aigner, T Meier Fedeler, D Eschbach, J Hack, C Bliemel, S Ruchholtz, B Bücking
: The aim of the present study was to identify patient factors associated with higher costs in hip fracture patients. The mean costs of a prospectively observed sample of 402 patients were 8853 €. The ASA score, Charlson comorbidity index, and fracture location were associated with increased costs. PURPOSE: Fractures of the proximal end of the femur (hip fractures) are of increasing incidence due to demographic changes. Relevant co-morbidities often present in these patients cause high complication rates and prolonged hospital stays, thus leading to high costs of acute care...
December 2016: Archives of Osteoporosis
Serge Ferrari, Jean-Yves Reginster, Maria Luisa Brandi, John A Kanis, Jean-Pierre Devogelaer, Jean-Marc Kaufman, Jean-Marc Féron, Andreas Kurth, René Rizzoli
: This review provides a critical analysis of currently available approaches to increase bone mass, structure and strength through drug therapy and of possible direct intra-osseous interventions for the management of patients at imminent risk of hip fracture. PURPOSE: Osteoporotic hip fractures represent a particularly high burden in morbidity-, mortality- and health care-related costs. There are challenges and unmet needs in the early prevention of hip fractures, opening the perspective of new developments for the management of osteoporotic patients at imminent and/or at very high risk of hip fracture...
December 2016: Archives of Osteoporosis
Mohammad Reza Bordbar, Sezaneh Haghpanah, Mohammad Hossein Dabbaghmanesh, Gholamhossein Ranjbar Omrani, Forough Saki
: Acute leukemia is the most common malignancy in children. We showed that low bone mass is prevalent among children with leukemia, especially in femur. Serum calcium, exercise, chemotherapy protocol, and radiotherapy are the main contributing factors. We suggest that early diagnosis and treatment of this problem could improve bone health in them. INTRODUCTION: Acute leukemia is the most common malignancy in children and has been reported to be associated with low bone mass...
December 2016: Archives of Osteoporosis
Shaoguang Li, Tiansheng Sun, Zhi Liu
: In a rapidly aging population, hip fractures have become an important public health issue in China. Presently, there is no study on the excess mortality of hip fractures in the mainland of China. This is the first study that presents excess mortality following hip fracture in Beijing, China. PURPOSE: This study aims to assess the incidence and excess mortality of hip fracture patients aged 60 years or older from a municipal population database of Beijing. METHODS: We retrieved the Beijing municipal health insurance database of 2013 to identify beneficiaries who were at least 60 years older as total population of this age group and obtained the number of mortalities in a year...
December 2016: Archives of Osteoporosis
Joerg Schiller, Christoph Korallus, Matthias Bethge, Matthias Karst, Marie-Lena Schmalhofer, Christoph Gutenbrunner, Matthias Georg Fink
: In this sham-controlled study, 53 patients received 10 sessions of acupuncture treatment over 5 weeks to investigate the effects of acupuncture on the pain and quality of life of patients with osteoporosis. The results showed significant favorable effects of verum acupuncture on quality of life. Both interventions showed sustained and clinically relevant effects on pain. PURPOSE: Standard analgesic treatment is associated with adverse events in patients with osteoporosis, especially elderly and/or comorbid patients...
December 2016: Archives of Osteoporosis
K L Barker, F Toye, C J Minns Lowe
: We aimed to systematically review qualitative studies exploring the experience of living with osteoporosis to develop new conceptual understanding. We identified themes about the invisibility/visibility of osteoporosis, the experience of uncertainty of living with osteoporosis (OP) and living with an ageing body and the place of gender. PURPOSE: The aim of this review was to systematically review the body of qualitative studies exploring the experience of living with either osteoporosis or osteopenia and to use meta-ethnography to develop new conceptual understanding...
December 2016: Archives of Osteoporosis
David J Armstrong, Rhonda Hunter
No abstract text is available yet for this article.
December 2016: Archives of Osteoporosis
Akeem A Yusuf, Thomas J Matlon, Andreas Grauer, Richard Barron, David Chandler, Yi Peng
: Osteoporosis medications are recommended for elderly patients after a fragility fracture. However, we found substantial under-treatment in the post-fracture year, especially among patients who had not previously received such medications. Improved treatment of elderly patients experiencing fragility fractures is needed. INTRODUCTION: Osteoporosis medications are recommended for elderly patients after a fragility fracture, but under-treatment is common. We determined osteoporosis medication use after fragility fractures and examined associated factors...
December 2016: Archives of Osteoporosis
Éric Tremblay, Sylvie Perreault, Marc Dorais
: Persistence to denosumab or zoledronic acid was increased compared to oral bisphosphonates. INTRODUCTION: Denosumab and zoledronic acid are alternative therapies to oral bisphosphonates. Few studies have assessed persistence of those agents. METHODS: Incident users of denosumab and zoledronic acid were identified using healthcare databases of public drug insurance plan of Quebec province, Canada. Patients initiating therapy between October 1, 2008, and June 30, 2013, and aged 50 years and over were eligible...
December 2016: Archives of Osteoporosis
Shalinie King, Iven Klineberg, Itamar Levinger, Tara C Brennan-Speranza
UNLABELLED: Patients with type 2 diabetes mellitus have a higher risk of dental and/or orthopaedic implant failure. However, the mechanism behind this phenomenon is unclear, and animal studies may prove useful in shedding light on the processes involved. This review considers the available literature on rat models of diabetes and titanium implantation. INTRODUCTION: The process of osseointegration whereby direct contact is achieved between bone and an implant surface depends on healthy bone metabolism...
December 2016: Archives of Osteoporosis
Smita Jha, Timothy Bhattacharyya
UNLABELLED: There is a strong impetus to prevent and treat osteoporosis to prevent fractures. $990 million dollars was spent on anti-osteoporosis drugs in 2013. As we shift our focus on primary prevention of fractures, providers are encouraged to find the most cost-effective anti-osteoporosis therapy for patients. PURPOSE: Osteoporosis is a major global problem with osteoporotic fractures posing a potentially avoidable burden on healthcare resources. We studied the utilization and cost of anti-osteoporotic therapy using the 2013 Medicare Part D data...
December 2016: Archives of Osteoporosis
Felipe Welter Langer, Antonio Aurelio da Silveira Codevilla, Raisa Bringhenti, Léo Canterle Dal Osto, Thabara Renaty Sanchez Campos, Tamires Tolazzi Martins, Ana Elize Barin, Pietro Hagamenon Rigo, Natalia Diel Boufleuer, Sheyla Fabiane Santinon, Kaira Kipper, Juliano Rodrigues, Melissa Orlandin Premaor
UNLABELLED: Postmenopausal women with a high risk of fractures may not perceive their risk. This study showed no concordance between the perceived and calculated risk of fracture. Almost 80 % of the women identified as a high risk of fracture by the FRAX algorithm tool perceived themselves to have little risk. PURPOSE: This study aimed to assess the concordance between self-perception of osteoporosis and fracture risk and the 10-year risk of fractures calculated by the FRAX algorithm...
December 2016: Archives of Osteoporosis
M Bonafede, N Shi, R Barron, X Li, D B Crittenden, D Chandler
UNLABELLED: Patient characteristics contributing to imminent risk for fracture, defined as risk of near-term fracture within the next 12 to 24 months, have not been well defined. In patients without recent fracture, we identified factors predicting imminent risk for vertebral/nonvertebral fracture, including falls, age, comorbidities, and other potential fall risk factors. PURPOSE: Several factors contribute to long-term fracture risk in patients with osteoporosis, including age, bone mineral density, and fracture history...
December 2016: Archives of Osteoporosis
John A Kanis, Nicholas C Harvey, Cyrus Cooper, Helena Johansson, Anders Odén, Eugene V McCloskey
UNLABELLED: This systematic review identified assessment guidelines for osteoporosis that incorporate FRAX. The rationale for intervention thresholds is given in a minority of papers. Intervention thresholds (fixed or age-dependent) need to be country-specific. INTRODUCTION: In most assessment guidelines, treatment for osteoporosis is recommended in individuals with prior fragility fractures, especially fractures at spine and hip. However, for those without prior fractures, the intervention thresholds can be derived using different methods...
December 2016: Archives of Osteoporosis
Aissam El Maataoui, Asmae Biaz, Samira El Machtani, Sanae Bouhsain, Abdellah Dami, Abdellah El Maghraoui, Zohra Ouzzif
UNLABELLED: This study aimed to compare the vitamin D status in healthy Moroccan men and women aged 50 years and older. A total of 186 Moroccan women and 68 men, who had no previous diagnosis of osteoporosis, were recruited prospectively. We found in this study a high prevalence of hypovitaminosis D with no difference between men and women. PURPOSE: The main purpose of this study was to describe and compare the vitamin D status, parathormone, calcium, and phosphate of healthy Moroccan men and women aged 50 years and older...
December 2016: Archives of Osteoporosis
Roland D Chapurlat, Georges Boivin
No abstract text is available yet for this article.
2016: Archives of Osteoporosis
Taylor C Wallace, Douglas C Bauer, Robert F Gagel, Susan L Greenspan, Joan M Lappe, Meryl S LeBoff, Robert R Recker, Kenneth G Saag, Andrea J Singer
The methods and processes described in this manuscript have been approved and adopted by the NOF Board of Trustees on November 11, 2015. This manuscript has been peer-reviewed by the NOF Research Committee and Osteoporosis International. The National Osteoporosis Foundation frequently publishes position statements for the benefit of educating healthcare professionals and the general public on a particular issue and/or concern related to preventing osteoporosis and/or promoting strong bones throughout the lifespan...
2016: Archives of Osteoporosis
M L Brandi
No abstract text is available yet for this article.
2016: Archives of Osteoporosis
Lior Benzvi, Adam Gershon, Idit Lavi, Ronit Wollstein
UNLABELLED: A retrospective study evaluated a large health maintenance organization for secondary prevention of osteoporosis following fragility fractures of the distal radius. Our population remained undiagnosed and untreated despite the ability of the system to provide adequate care. These patients specifically should be targeted for a comprehensive multidisciplinary effort at prevention. PURPOSE: Osteoporotic wrist fractures carry a high risk for subsequent fragility fractures...
2016: Archives of Osteoporosis
Brianna R Lindsay, Temitope Olufade, Jennifer Bauer, Jane Babrowicz, Rebecca Hahn
UNLABELLED: We investigated reasons for non-treatment of osteoporosis and discontinuation of osteoporosis therapy. Barriers to treatment include patients' preference for alternative treatments and a fear of possible side effects. Side effects are a common reason for treatment discontinuation, and they may be associated with a lack of willingness to restart treatment. PURPOSE/INTRODUCTION: Osteoporosis patients commonly cite treatment-related side effects, or the fear thereof, as a reason for discontinuing or not initiating anti-osteoporosis medications...
2016: Archives of Osteoporosis
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