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Archives of Osteoporosis

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https://www.readbyqxmd.com/read/28343298/thiazide-increases-serum-calcium-in-anuric-patients-the-role-of-parathyroid-hormone
#1
Raquel F V Vasco, Eduardo T Reis, Rosa M A Moyses, Rosilene M Elias
We evaluated the effect of hydrochlorothiazide in a sample of anuric patients on hemodialysis and found an increase in serum calcium, which occurred only in those with parathyroid hormone >300 pg/ml. This finding highlights the extra-renal effect of this diuretic and a possible role of parathyroid hormone in the mechanism. PURPOSE: Thiazide diuretics are commonly used in patients with chronic kidney disease to treat hypertension. Their effects on calcium and bone metabolism are not well established, once calciuria may not fully explain levels of calcium and parathyroid hormone (PTH) in this population...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28332125/osteoarthritis-of-the-hip-joint-in-elderly-patients-is-most-commonly-atrophic-with-low-parameters-of-acetabular-dysplasia-and-possible-involvement-of-osteoporosis
#2
Yasuhiro Ishidou, Kanehiro Matsuyama, Daisuke Sakuma, Takao Setoguchi, Satoshi Nagano, Ichiro Kawamura, Shingo Maeda, Setsuro Komiya
As elderly patients with hip osteoarthritis aged, acetabular dysplasia parameters decreased (Sharp's angle, acetabular roof obliquity angle, and acetabular head index) and the incidence of the atrophic type increased. Vertebral body fracture was more frequent in the atrophic type, suggesting the involvement of osteoporosis at the onset of hip osteoarthritis. INTRODUCTION: Osteoarthritis (OA) is associated with increased bone formation at a local site. However, excessive bone resorption has also been found to occur in the early stages of OA...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28286929/cannabis-use-and-bone-mineral-density-nhanes-2007-2010
#3
Donald Bourne, Wesley Plinke, Elizabeth R Hooker, Carrie M Nielson
Cannabis use is rising in the USA. Its relationship to cannabinoid signaling in bone cells implies its use could affect bone mineral density (BMD) in the population. In a national survey of people ages 20-59, we found no association between self-reported cannabis use and BMD of the hip or spine. INTRODUCTION: Cannabis is the most widely used illegal drug in the USA, and its recreational use has recently been approved in several US states. Cannabinoids play a role in bone homeostasis. We aimed to determine the association between cannabis use and BMD in US adults...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28283938/seasonal-variation-in-internet-searches-for-vitamin-d
#4
Rebecca J Moon, Elizabeth M Curtis, Justin H Davies, Cyrus Cooper, Nicholas C Harvey
Internet search rates for "vitamin D" were explored using Google Trends. Search rates increased from 2004 until 2010 and thereafter displayed a seasonal pattern peaking in late winter. This knowledge could help guide the timing of public health interventions aimed at managing vitamin D deficiency. PURPOSE: The Internet is an important source of health information. Analysis of Internet search activity rates can provide information on disease epidemiology, health related behaviors and public interest...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28283937/effect-of-bisphosphonate-initiation-at-week-2-versus-week-12-on-short-term-functional-recovery-after-femoral-neck-fracture-a-randomized-controlled-trial
#5
Aasis Unnanuntana, Panai Laohaprasitiporn, Atthakorn Jarusriwanna
The appropriate time to initiate bisphosphonate treatment after a fragility fracture has not yet been established. In this study, we found no significant differences in short-term functional recovery between femoral neck fracture patients who received bisphosphonate treatment at 2 versus 12 weeks after hemiarthroplasty. INTRODUCTION: Bisphosphonate is the mainstay therapy for prevention and treatment of osteoporosis. The aim of this study was to investigate the effect of bisphosphonate initiation on short-term functional recovery in femoral neck fracture patients at 2 versus 12 weeks after hemiarthroplasty...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28265896/use-of-cone-beam-computed-tomography-in-identifying-postmenopausal-women-with-osteoporosis
#6
C B Brasileiro, L L F H Chalub, M H N G Abreu, I D Barreiros, T M P Amaral, A M Kakehasi, R A Mesquita
The aim of this study is to correlate radiometric indices from cone beam computed tomography (CBCT) images and bone mineral density (BMD) in postmenopausal women. Quantitative CBCT indices can be used to screen for women with low BMD. PURPOSE: Osteoporosis is a disease characterized by the deterioration of bone tissue and the consequent decrease in BMD and increase in bone fragility. Several studies have been performed to assess radiometric indices in panoramic images as low-BMD predictors...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28255680/erratum-to-unmet-needs-and-current-and-future-approaches-for-osteoporotic-patients-at-high-risk-of-hip-fracture
#7
Serge Ferrari, Jean-Yves Reginster, Maria Luisa Brandi, John A Kanis, Jean-Pierre Devogelaer, Jean-Marc Kaufman, Jean-Marc Féron, Andreas Kurth, René Rizzoli
No abstract text is available yet for this article.
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28251468/low-prevalence-of-osteoporosis-treatment-in-patients-with-recurrent-major-osteoporotic-fracture
#8
J Flais, G Coiffier, J Le Noach, J D Albert, M Faccin, A Perdriger, H Thomazeau, P Guggenbuhl
The majority of patients do not receive anti-osteoporotic treatment following a major osteoporotic fracture, despite the guidelines and the availability of effective anti-osteoporotic treatments. The fight against factors limiting the diagnosis and treatment of osteoporosis should become a priority to improve secondary prevention after an initial osteoporotic fracture. PURPOSE: Despite the availability of effective anti-osteoporotic treatments, osteoporosis management is currently insufficient...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28247259/vertebral-fracture-assessment-in-patients-presenting-with-a-non-hip-non-vertebral-fragility-fracture-experience-of-a-uk-fracture-liaison-service
#9
Aina Capdevila Reniu, Terence Ong, Syed Ajmal, Opinder Sahota
Twenty-five percent of patients with a non-hip non-vertebral fragility fracture have an undiagnosed vertebral fracture detected by vertebral fracture assessment during bone densitometric assessment. The prevalence of an undiagnosed vertebral fracture is higher in older people, and they are more likely to have multiple vertebral fractures. PURPOSE: Most vertebral fragility fractures (VFF) have no history of trauma. Vertebral fracture assessment (VFA) during dual energy x-ray absorptiometry (DXA) can be used to detect these VFFs...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28243883/two-year-persistence-and-compliance-with-osteoporosis-therapies-among-postmenopausal-women-in-a-commercially-insured-population-in-the-united-states
#10
Emily Durden, Lionel Pinto, Lorena Lopez-Gonzalez, Paul Juneau, Richard Barron
This retrospective, observational study assessed 2-year persistence and compliance by treatment, route of administration, and dosing frequency in postmenopausal women initiating a new osteoporosis therapy. Two-year persistence and compliance rates were higher in women receiving injectables compared with oral agents. PURPOSE: This study extends previous studies limited to 1-year follow-up by examining persistence with osteoporosis therapies over a 2-year period and compares short- and long-term trends in persistence and compliance among postmenopausal women with commercial or Medicare supplemental insurance in the USA...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28243882/improving-patient-outcomes-in-fibrous-dysplasia-mccune-albright-syndrome-an-international-multidisciplinary-workshop-to-inform-an-international-partnership
#11
A M Boyce, A Turner, L Watts, L Forestier-Zhang, A Underhill, R Pinedo-Villanueva, F Monsell, D Tessaris, C Burren, L Masi, N Hamdy, M L Brandi, R Chapurlat, M T Collins, Muhammad Kassim Javaid
To develop consensus on improving the management of patients, we convened an international workshop involving patients, clinicians, and researchers. Key findings included the diagnostic delay and variability in subsequent management with agreement to develop an international natural history study. We now invite other stakeholders to join the partnership. PURPOSE: The aim of this study was develop a consensus on how to improve the management of patients with fibrous dysplasia and prioritize areas for research METHODS: An international workshop was held over 3 days involving patients, clinicians, and researchers...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28210985/lumbar-disc-degeneration-was-not-related-to-spine-and-hip-bone-mineral-densities-in-chinese-facet-joint-osteoarthritis-may-confound-the-association
#12
Jianjiang Pan, Xuan Lu, Ge Yang, Yongmei Han, Xiang Tong, Yue Wang
A sample of 512 Chinese was studied and we observed that greater disc degeneration on MRI was associated with greater spine DXA BMD. Yet, this association may be confounded by facet joint osteoarthritis. BMD may not be a risk factor for lumbar disc degeneration in Chinese. PURPOSE: Evidence suggested that lumbar vertebral bone and intervertebral disc interact with each other in multiple ways. The current paper aims to determine the association between bone mineral density (BMD) and lumbar disc degeneration using a sample of Chinese...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28197890/relationships-among-diet-physical-activity-and-dual-plane-dual-energy-x-ray-absorptiometry-bone-outcomes-in-pre-pubertalgirls
#13
Jie Ren, Lynn S Brann, Kay S Bruening, Tamara A Scerpella, Jodi N Dowthwaite
In pre-pubertal girls, nutrient intakes and non-aquatic organized activity were evaluated as factors in vertebral body bone mass, structure, and strength. Activity, vitamin B12, and dietary fiber predicted bone outcomes most consistently. Exercise and vitamin B12 appear beneficial, whereas high fiber intake appears to be adverse for vertebral body development. PURPOSE: Childhood development sets the baseline for adult fracture risk. Most studies evaluate development using postero-anterior (PA) dual-energy X-ray absorptiometry (DXA) areal bone mineral density, bone mineral content, and bone mineral apparent density...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28190173/unparallel-gender-specific-changes-in-the-incidence-of-hip-fractures-in-tangshan-china
#14
Fa-Ming Tian, Xiao-Xin Sun, Jia-Yin Liu, Zhi-Kui Liu, Chun-Yu Liang, Liu Zhang
This study, which measured the incidence of hip fractures in Tangshan, China, in 2015, shows that compared to data we reported in Tangshan in 2010, the crude incidence of hip fractures in 2015 increased in females and slightly decreased in males. However, the incidences of age-specific hip fracture in females aged over 65 and males aged over 75 are both increasing. INTRODUCTION: The purpose of this study was to assess the incidence of hip fractures in 2015 in Tangshan, China, and to compare this incidence with that previously reported in Tangshan in 2010...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28188561/patient-specific-prescriber-feedback-can-increase-the-rate-of-osteoporosis-screening-and-treatment-results-from-two-national-interventions
#15
Lisa M Kalisch Ellett, N L Pratt, J K Sluggett, E N Ramsay, M Kerr, V T LeBlanc, J D Barratt, E E Roughead
Osteoporosis interventions targeting older Australians and clinicians were conducted in 2008 and 2011 as part of a national quality improvement program underpinned by behavioural theory and stakeholder engagement. Uptake of bone mineral density (BMD) tests among targeted men and women increased after both interventions and sustained increases in osteoporosis treatment were observed among men targeted in 2008. PURPOSE: Educational interventions incorporating patient-specific prescriber feedback have improved osteoporosis screening and treatment among at-risk patients in clinical trials but have not been evaluated nationally...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28155141/compliance-to-the-joint-commission-proposed-core-measure-set-on-osteoporosis-associated-fracture-review-of-different-secondary-fracture-prevention-programs-in-an-open-medical-system-from-2010-to-2015
#16
Ma Conchitina Fojas, Lauren T Southerland, Laura S Phieffer, Julie A Stephens, Tanya Srivastava, Steven W Ing
There are care gaps in the evaluation and treatment of osteoporosis after a fragility fracture. The Joint Commission is considering adoption of core measures. We compared compliance between two secondary fracture prevention programs in our institution. Incorporating strengths of both may provide the best outcomes for secondary fracture prevention. PURPOSE: There are significant care gaps in the evaluation and treatment of osteoporosis after occurrence of fragility fracture. The Joint Commission is considering adoption of a core measure set on osteoporosis-associated fractures, including laboratory assessment, bone density testing, and osteoporosis pharmacologic therapy...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28155140/teriparatide-treatment-of-femoral-fracture-nonunion-that-autogenous-bone-grafting-failed-to-heal-a-case-report
#17
Wei Yu, Xiaodong Guo
PURPOSE: Management of fracture nonunion is challenging as another surgical intervention for the patient is often a necessity, which has a huge impact on both quality of life and economic burden of the patient. Thus, a less aggressive and better accepted treatment for nonunion is required. METHODS: We gave teriparatide to a 45-year-old man with femoral fracture nonunion 1 year after he underwent surgery with autogenous bone grafting that failed to heal his initial nonunion...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28127706/new-insights-into-the-tonifying-kidney-yin-herbs-and-formulas-for-the-treatment-of-osteoporosis
#18
REVIEW
Jian-Bo He, Mei-Hui Chen, Ding-Kun Lin
Osteoporosis is characterized by an increasing osseous fragility and fracture resulting from the low mass and deteriorated microarchitecture in the bone tissue. The hormone replacement therapy and alendronate were frequently used to treat osteoporosis as the primary therapeutic strategy, but their adverse effects have severely limited their extensive clinical application, therefore, it is urgent to develop alternative or complementary therapeutic agents for anti-osteoporosis. Interestingly, with more people focusing on the complementary and alternative medicine, traditional Chinese herbs and formulas are being gradually recognized as safe and effective agents in the treatment of osteoporosis...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28124221/serum-25-hydroxyvitamin-d-and-bone-turnover-markers-in-palestinian-postmenopausal-osteoporosis-and-normal-women
#19
Akram Kharroubi, Elias Saba, Riham Smoom, Khaldoun Bader, Hisham Darwish
This study evaluated the association of vitamin D and bone markers with the development osteoporosis in Palestinian postmenopausal women. Even though vitamin D deficiency was very high for the recruited subjects, it was not associated with osteoporosis except for bones of the hip. Age and obesity were the strongest determining factors of the disease. PURPOSE: The purpose of this study was to investigate the association of bone mineral density (BMD) with serum vitamin D levels, parathyroid hormone (PTH), calcium, obesity, and bone turnover markers in Palestinian postmenopausal women...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28120256/osteoporosis-among-hospitalized-patients-with-proximal-femoral-fractures-in-assiut-university-trauma-unit-egypt
#20
Osama Farouk, Dalia G Mahran, Hatem G Said, Mohamed M Alaa, Amr Eisa, Hisham Imam, G Z Said
The study was done to investigate osteoporosis prevalence in 275 hip fracture admissions at the Trauma Unit of Assiut University Hospitals and associated factors, which are understudied in our locality. Prevalence was 74.9%. Female sex, older age, low body mass index, and fall on the ground were associated with osteoporosis. PURPOSE: This study aims to identify osteoporosis prevalence in hip fracture admissions at the Trauma Unit of Assiut University Hospitals and to study the independent correlates of osteoporosis-related fracture...
December 2017: Archives of Osteoporosis
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