journal
MENU ▼
Read by QxMD icon Read
search

Journal of Crohn's & Colitis

journal
https://www.readbyqxmd.com/read/28082310/very-early-onset-ibd-how-very-different-on-average
#1
EDITORIAL
Dan Turner, Aleixo M Muise
No abstract text is available yet for this article.
January 12, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28039310/european-crohn-s-and-colitis-organisation-topical-review-on-environmental-factors-in-ibd
#2
Christian Maaser, Ebbe Langholz, Hannah Gordon, Johan Burisch, Pierre Ellul, Vicent Hernández Ramirez, Tarkan Karakan, Konstantinos H Katsanos, Eduards Krustins, Arie Levine, Gerassimos J Mantzaris, Colm O'Morain, Elif Saritas Yuksel, Hans Strid, Vito Annese
This ECCO topical review of the European Crohn's and Colitis Organisation (ECCO) focuses on the role of environmental factors in respect to the development of IBD as well as the influence on the course of established IBD.The objective was to reach expert consensus to provide evidence-based guidance for clinical practice.
December 30, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28039309/tissue-nonspecific-alkaline-phosphatase-expression-is-needed-for-the-full-stimulation-of-t-cells-and-t-cell-dependent-colitis
#3
Cristina Hernández-Chirlaque, Reyes Gámez-Belmonte, Borja Ocón, Patricia Martínez-Moya, Stefan Wirtz, Fermín Sánchez de Medina, Olga Martínez-Augustin
BACKGROUND AND AIMS: Two alkaline phosphatase isoforms, intestinal (IAP) and tissue non-specific alkaline phosphatase (TNAP), are coexpressed in mouse colon, with the latter predominating in colitis. We aimed to examine the role of TNAP in T lymphocytes using heterozygous TNAP(+/-) mice (as TNAP(-/-) mice are nonviable). METHODS: In vitro primary cultures and in vivo T cell models using TNAP(+/-) mice were used. RESULTS: Stimulated splenocytes (lipopolysaccharide and concanavalin A) and T lymphocytes (concanavalin A and a-CD3/a-CD28) showed a decreased cytokine production and expression when compared with WT cells...
December 30, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28039308/corrigendum
#4
(no author information available yet)
No abstract text is available yet for this article.
December 30, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28025307/five-year-safety-data-from-encore-a-european-observational-safety-registry-for-adults-with-crohn-s-disease-treated-with-infliximab-remicade%C3%A2-or-conventional-therapy
#5
Geert D'Haens, Walter Reinisch, Jean-Frederic Colombel, Julian Panes, Subrata Ghosh, Cosimo Prantera, Stefan Lindgren, Daniel W Hommes, Zhiping Huang, Judith Boice, Susan Huyck, Freddy Cornillie
BACKGROUND AND AIMS: The ENCORE registry aimed at comparing the long-term safety of Crohn's disease [CD] treatment with infliximab [Remicade(®)] and with conventional therapies in real-world clinical practice. METHODS: The 5-year, prospective, observational ENCORE registry followed patients with CD in nine European countries, who received treatment with infliximab, conventional therapies, or switched to infliximab from conventional therapy. Adverse events [AEs] in pre-specified categories and serious AEs were recorded at least every 6 months of the 5-year observation period...
December 26, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28025306/risks-and-benefits-of-mucosal-healing-with-combined-immunosuppression-in-paediatric-crohn-s-disease-a-complex-topic-that-needs-careful-evaluation
#6
LETTER
Stefano Nobile, Paolo Gionchetti, Massimo Campieri
No abstract text is available yet for this article.
December 26, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27993998/the-pathogenic-role-of-nlrp3-inflammasome-activation-in-inflammatory-bowel-diseases-of-both-mice-and-humans
#7
Ling Liu, Ying Dong, Mei Ye, Shi Jin, Jianbo Yang, Maria E Joosse, Yu Sun, Jennifer Zhang, Mark Lazarev, Steven R Brant, Bashar Safar, Michael Marohn, Esteban Mezey, Xuhang Li
BACKGROUND AND AIMS: NLRP3 inflammasome is known to be involved in inflammatory bowel diseases. However, it is controversial if it is pathogenic or beneficial. This study evaluated the roles of NLRP3-inflammasome in the pathogenesis of inflammatory bowel disease in IL-10-/- mice and humans. METHODS: NLRP3 inflammasome in colonic mucosa, macrophages, and colonic epithelial cells were analyzed by Western blotting. The NLRP3 inflammasome components were studied by sucrose density gradient fractionation, chemical crosslinking and co-immunoprecipitation...
December 17, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27993997/letter-vedolizumab-in-pregnancy
#8
LETTER
Juliette Sheridan, Garret Cullen, Glen Doherty
No abstract text is available yet for this article.
December 17, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27993996/fluoxetine-for-maintenance-of-remission-and-to-improve-quality-of-life-in-patients-with-crohn-s-disease
#9
LETTER
Cong Dai, Min Jiang, Ming-Jun Sun
No abstract text is available yet for this article.
December 17, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27986839/optimisation-of-intestinal-fibrosis-and-survival-in-the-mouse-s-typhimurium-model-for-anti-fibrotic-drug-discovery-and-preclinical-applications
#10
Laura A Johnson, Eva S Rodansky, David S Moons, Scott D Larsen, Richard R Neubig, Peter D R Higgins
BACKGROUND AND AIMS: Intestinal fibrosis is a frequent complication in Crohn's disease [CD]. The mouse Salmonella typhimurium model, due to its simplicity, reproducibility, manipulability, and penetrance, is an established fibrosis model for drug discovery and preclinical trials. However, the severity of fibrosis and mortality are host- and bacterial strain-dependent, thus limiting the original model. We re-evaluated the S. typhimurium model to optimise fibrosis and survival, using commercially available mouse strains...
December 16, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27932454/inducible-colonic-m-cells-are-dependent-on-tnfr2-but-not-lt%C3%AE-r-identifying-distinct-signalling-requirements-for-constitutive-versus-inducible-m-cells
#11
Erinn A Parnell, Erin M Walch, David D Lo
BACKGROUND AND AIMS: M cells associated with organised lymphoid tissues such as intestinal Peyer's patches provide surveillance of the intestinal lumen. Inflammation or infection in the colon can induce an M cell population associated with lymphoid infiltrates; paradoxically, induction is dependent on the inflammatory cytokine tumour necrosis factor [TNF]-α. Anti-TNFα blockade is an important therapeutic in inflammatory bowel disease, so understanding the effects of TNFα signalling is important in refining therapeutics...
December 7, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27932453/preoperative-vedolizumab-and-postoperative-outcomes-in-inflammatory-bowel-disease-does-smoke-always-mean-fire
#12
LETTER
Paulo Gustavo Kotze, Takayuki Yamamoto
No abstract text is available yet for this article.
December 7, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27932452/patients-beliefs-and-concerns-about-the-necessity-of-long-term-therapies-are-crucial-for-medication-adherence-for-inflammatory-bowel-disease
#13
LETTER
Marco Vincenzo Lenti, Christian P Selinger
No abstract text is available yet for this article.
December 7, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27932451/extra-pulmonary-reactivation-of-latent-tuberculosis-after-initiation-of-anti-tumour-necrosis-factor-therapy-for-inflammatory-bowel-disease-are-current-screening-strategies-adequate
#14
LETTER
Thomas H Tranah, Shin Y Luk, Markus Gess
No abstract text is available yet for this article.
December 7, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27932450/accuracy-of-diffusion-weighted-magnetic-resonance-colonography-in-assessing-mucosal-healing-and-the-treatment-response-in-patients-with-ulcerative-colitis
#15
Valérie Laurent, Sébastien Naudé, Lucine Vuitton, Camille Zallot, Cédric Bauman, Mélanie Girard-Gavanier, Laurent Peyrin-Biroulet
BACKGROUND & AIMS: Using sigmoidoscopy as the gold standard, we assessed the accuracy and responsiveness to change of diffusion-weighted magnetic resonance colonography in ulcerative colitis using the Nancy score. METHODS: 29 ulcerative colitis patients having undergone at least two diffusion-weighted magnetic resonance colonographies were included. Disease activity was evaluated using the Mayo endoscopic subscore and the Nancy score. We determined the accuracy of the Nancy score in the diagnosis of mucosal healing...
December 7, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27932449/oral-iron-treatment-response-and-predictors-in-anaemic-adolescents-and-adults-with-ibd-a-prospective-controlled-open-label-trial
#16
David S Rampton, James R Goodhand, Neerav M Joshi, Abu-Bakarr Karim, Yasmine Koodun, Farah M Barakat, Lucia Macken, Douglas G Ward, Tariq H Iqbal, Jenny Epstein, John M Fell, Ian R Sanderson
BACKGROUND: Because of previous concerns about the efficacy and safety of oral iron for treating iron deficiency anaemia in inflammatory bowel disease [IBD], particularly in young people, we compared the effects of ferrous sulphate on haemoglobin response, disease activity and psychometric scores in adolescents and adults with IBD. We also assessed the relation of baseline serum hepcidin to haemoglobin response. METHODS: We undertook a prospective, open-label, 6-week non-inferiority trial of the effects of ferrous sulphate 200 mg twice daily on haemoglobin, iron status, hepcidin, disease activity (Harvey-Bradshaw Index, Simple Colitis Clinical Activity Index, C-reactive protein [CRP]), faecal calprotectin and psychometric scores in 45 adolescents [age 13-18 years] and 43 adults [>18 years]...
December 7, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27927720/restorative-proctocolectomy-in-elderly-ibd-patients-a-multicentre-comparative-study-on-safety-and-efficacy
#17
Francesco Colombo, Saloomeh Sahami, Antony de Buck Van Overstraeten, Hagit Tulchinsky, Diane Mege, Iris Dotan, Diego Foschi, Cosimo Alex Leo, Janindra Warusavitarne, André D'Hoore, Yves Panis, Willem Bemelman, Gianluca M Sampietro
BACKGROUND AND AIMS: Restorative proctocolectomy in elderly inflammatory bowel disease [ IBD] patients is controversial and limited data are available on the outcomes of surgery. The aim of this study was to evaluate the safety, efficacy, and long-term results of ileal-pouch-anal anastomosis in elderly patients, in a multicentre survey from European referral centres. METHODS: The International Pouch Database [IPD] combined 101 variables. Patients aged ≥ 65 years were matched on the basis of open versus laparoscopic surgery with a control group of consecutive younger unselected patients with a ratio of 1:2...
December 7, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27927719/development-and-validation-of-risk-matrices-for-crohn-s-disease-outcomes-in-patients-submitted-to-early-therapeutic-interventions
#18
Cláudia Camila Dias, Pedro Pereira Rodrigues, Rosa Coelho, Paula Moura Santos, Samuel Fernandes, Paula Lago, Cidalina Caetano, Ângela Rodrigues, Francisco Portela, Ana Oliveira, Paula Ministro, Eugénia Cancela, Ana Isabel Vieira, Rita Barosa, José Cotter, Pedro Carvalho, Isabelle Cremers, Daniel Trabulo, Paulo Caldeira, Artur Antunes, Isadora Rosa, Joana Moleiro, Paula Peixe, Rita Herculano, Raquel Gonçalves, Bruno Gonçalves, Helena Tavares Sousa, Luís Contente, Henrique Morna, Susana Lopes, Fernando Magro
No abstract text is available yet for this article.
December 7, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27856523/beyond-histological-remission-intramucosal-calprotectin-as-a-potential-predictor-of-outcomes-in-ulcerative-colitis
#19
Marianne Guirgis, Emily Wendt, Lai Mun Wang, Alissa Walsh, Daniel Burger, Robert V Bryant, Alex Kent, Rebecca Adamson, Oliver Brain, Simon P L Travis, Satish Keshav
BACKGROUND AND AIMS: Histological remission and low faecal calprotectin are positive prognostic factors in ulcerative colitis [UC]. Intramucosal calprotectin [iMC], which can be readily determined by immunohistochemistry, has not so far been evaluated as a predictor of outcome in UC. We aimed to investigate the relationship between iMC and clinical, endoscopic, and histological measures of remission in UC, and the independent prognostic value of iMC. METHODS: Ambulant patients with UC were recruited for a study comparing clinical activity indices...
November 14, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27838610/prediction-of-short-and-medium-term-efficacy-of-biosimilar-infliximab-therapy-do-trough-levels-and-antidrug-antibody-levels-or-clinical-and-biochemical-markers-play-the-more-important-role
#20
Lorant Gonczi, Zsuzsanna Vegh, Petra Anna Golovics, Mariann Rutka, Krisztina Barbara Gecse, Renata Bor, Klaudia Farkas, Tamás Szamosi, László Bene, Beáta Gasztonyi, Tünde Kristóf, László Lakatos, Pál Miheller, Károly Palatka, Mária Papp, Árpád Patai, Ágnes Salamon, Gábor Tamás Tóth, Áron Vincze, Edina Biro, Barbara Dorottya Lovasz, Zsuzsanna Kurti, Zoltan Szepes, Tamás Molnár, Péter L Lakatos
BACKGROUND AND AIMS: Biosimilar infliximab CT-P13 received European Medicines Agency [EMA] approval in June 2013 for all indications of the originator product. In the present study, we aimed to evaluate the predictors of short- and medium-term clinical outcome in patients treated with the biosimilar infliximab at the participating inflammatory bowel disease [IBD] centres in Hungary. METHODS: Demographic data were collected and a harmonised monitoring strategy was applied...
November 12, 2016: Journal of Crohn's & Colitis
journal
journal
41775
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"