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International Archives of Medicine

Atif Ali Hashmi, Babar Malik, Muhammad Muzzammil Edhi, Naveen Faridi, Muhammad Ashraful
INTRODUCTION: Lipoma is a benign soft tissue neoplasm that may contain mesenchymal elements, as a result of metaplastic process. Ossification in benign and malignant soft tissue tumors can also manifest due to metaplastic process. CASE PRESENTATION: A 45 year old woman presented with a large thigh mass. The mass was developed one and a half year ago which insidiously increased in size and was associated with movement restriction. Radiological findings revealed soft tissue neoplasm on antero-medial aspect of thigh encircling the femur and displacing adjacent muscles...
January 16, 2014: International Archives of Medicine
Atif Ali Hashmi, Naveen Faridi, Muhammad Muzzammil Edhi, Asad Jafri, Mehmood Khan
Fibro-osseous pseudotumor of the digit is rare benign lesion of subcutaneous tissue which is thought to be reactive process as a result of repeated trauma. We report a case of an ulcerated lesion of skin of middle finger, clinically thought to be leishmaniasis which after punch biopsy followed by excision turned out to be fibrosseous pseudotumor. Diagnosis of fibro-osseous pseudotumor requires immense precision as it can clinically mimic unungal exostosis and can sometimes be misinterpreted clinically and radiologically as myositis ossificans...
January 9, 2014: International Archives of Medicine
Rodrigo A Gonçalves, Sérgio Feitosa, Cláudia de Selestrein, Vitor E Valenti, Fernando H de Sousa, Arnaldo A Siqueira, Márcio Petenusso, Luiz Carlos de Abreu
BACKGROUND: Acute viral bronchiolitis is a respiratory disease with high morbidity that affects newborn in the first two years of life. Its treatment with physiotherapy has been highlighted as an important tool, however, there is no consensus regarding its effects on patients improvement. We aimed to evaluate the physiological parameters before and after the procedure respiratory therapy in newborn with acute viral bronchiolitis. METHOD: This was a cross sectional observational study in 30 newborns with acute viral bronchiolitis and indicated for physiotherapy care in a hospitalized Urgency and Emergency Unit...
January 8, 2014: International Archives of Medicine
Hemal Ms Senanayake, Anujaya D Dedigama, Randil P De Alwis, Kanapathipillai Thirumavalavan
Hoffmann syndrome is a rare form of hypothyroid myopathy in adults characterized by presence of muscle weakness, stiffness and pseudohypertrophy. We report a 39 year old male with primary hypothyroidism diagnosed at childhood and not on regular thyroxine therapy who presented with fatigue, cold intolerance, constipation, exertional breathlessness, progressive proximal muscle weakness and swelling of the legs for one year. Examination revealed pseudohypertrophy of calf muscles with marked symmetrical proximal upper and lower limb weakness...
January 6, 2014: International Archives of Medicine
Paloma Pc De Araújo, Oséas F De Moura Filho, Vitor E Valenti, Sophia Motta Gallo, Marcela R Camargo, Karina G Say, Renata S Marcomini, Gonçalves de Oliveira, Carlos Bm Monteiro, Rubens Wajnsztejn, Luiz Carlos De Abreu
BACKGROUND: Although postural changes were already reported in blind adults, no previous study has investigated postural stability in blind children. Moreover, there are few studies which used a stabilometric instrument to measure postural balance. In this study we evaluated stabilometric paramaters in blind children. METHODS: We evaluated children between 7 to 12 years old, they were divided into two groups: Blind (n = 11) and age-matched control (n = 11) groups by using computerized stabilometry...
January 3, 2014: International Archives of Medicine
Akinyele Taofiq Akinlade, Anthonia Okeoghene Ogbera, Olufemi Adetola Fasanmade, Michael Adeyemi Olamoyegun
INTRODUCTION: HE are common acute complications of diabetes mellitus (DM) and include diabetic ketoacidosis (DKA), normo-osmolar hyperglycemic state (NHS) and hyperosmolar hyperglycemic state (HHS). They contribute a lot to the mortality and morbidity of DM. The clinical features include dehydration, hyperglycemia, altered mental status and ketosis. The basic mechanism of HE is a reduction in the net effective action of circulating insulin, resulting in hyperglycemia and ketonemia (in DKA) causing osmotic diuresis and electrolytes loss...
2014: International Archives of Medicine
Samreen Naz, Atif Ali Hashmi, Amna Khurshid, Naveen Faridi, Muhammad Muzzammil Edhi, Anwar Kamal, Mehmood Khan
INTRODUCTION: Thyroid swelling is common problem among South Asian women. Although benign nodules far outnumber cancerous lesions, the risk of malignancy needs to be evaluated preoperatively for which fine needle aspiration cytology (FNAC) is widely used. Bethesda system for reporting thyroid cytopathology (BSRTC) was introduced to streamline the reporting of thyroid aspirates. We aimed to evaluate the disease spectrum of thyroid cytopathology and correlation of BSRTC with final histopathology in our setup...
2014: International Archives of Medicine
Adriano L Roque, Vitor E Valenti, Thais Massetti, Talita Dias da Silva, Carlos Bandeira de Mello Monteiro, Fernando R Oliveira, Álvaro Dantas de Almeida Junior, Sheylla Nadjane Batista Lacerda, Gustavo Carreiro Pinasco, Viviane Gabriela Nascimento, Luiz Gonzaga Granja Filho, Luiz Carlos de Abreu, David M Garner, Celso Ferreira
BACKGROUND: The literature indicates that chronic obstructive pulmonary disease (COPD) affects cardiac autonomic control. In this study, we conducted a literature review in order to investigate the heart rate variability (HRV) in COPD subjects. METHODS: A search was performed in Medline database, using the link between the keywords: "autonomic nervous system", "cardiovascular system", "COPD" and "heart rate variability". RESULTS: The search resulted in a total of 40 references...
2014: International Archives of Medicine
Igor Brauns, Silmar Teixeira, Bruna Velasques, Juliana Bittencourt, Sergio Machado, Mauricio Cagy, Mariana Gongora, Victor Hugo Bastos, Dionis Machado, Ada Sandoval-Carrillo, Jose Salas-Pacheco, Roberto Piedade, Pedro Ribeiro, Oscar Arias-Carrión
Many different factors can temporarily or permanently impair movement and impairs cortical organization, e.g. hand immobilization. Such changes have been widely studied using electroencephalography. Within this context, we have investigated the immobilization effects through the theta band coherence analysis, in order to find out whether the immobilization period causes any changes in the inter and intra-hemispheric coherence within the cerebral cortex, as well as to observe whether the theta band provides any information about the neural mechanisms involved during the motor act...
2014: International Archives of Medicine
Claudio Portella, Sergio Machado, Flávia Paes, Mauricio Cagy, Alexander T Sack, Ada Sandoval-Carrillo, Jose Salas-Pacheco, Adriana Cardoso Silva, Roberto Piedade, Pedro Ribeiro, Antonio Egídio Nardi, Oscar Arias-Carrión
The human brain is a system consisting of various interconnected neural networks, with functional specialization coexisting with functional integration occurring both; temporally and spatially at many levels. The current study ranked and compared fast and slow participants in processing information by assessing latency and amplitude of early and late Event-Related Potential (ERP) components, including P200, N200, Premotor Potential (PMP) and P300. In addition, the Reaction Time (RT) of participants was compared and related to the respective ERP components...
2014: International Archives of Medicine
Muhammad Muslim Noorani, Muhammad Farhan Khaliq, Maria Shoaib, Asfandyar Sheikh, Um-E-Roman Moughal, Wardah Moazzum, Syed Arsalan Ali
The objective of this study is to determine the time interval from decision to seek medical help and arrival of the patients to the emergency department (ED). The duration of stay in ED was also calculated. This study also assesses factors responsible delayed presentation to hospital. This prospective study was conducted during day timings (9 am to 3 pm) from May 2012 to August 2012 in ED at Civil Hospital, Karachi. Patients older than 18 years and meeting the inclusion criteria were considered to be eligible for the study...
2014: International Archives of Medicine
Maha Louriz, Jihane Belayachi, Bouchra Armel, Tarek Dendane, Khalid Abidi, Naoufel Madani, Aicha Zekraoui, Abdellatif Belabes Benchekroun, Amine Ali Zeggwagh, Redouane Abouqal
BACKGROUND: In the light of the impact that pain has on patients, emergency department (ED) physicians need to be well versed in its management, particularly in its acute presentation. The goal of the present study was to evaluate the prevalence of unrelieved acute pain during ED stay in a Moroccan ED, and to identify risk factors of unrelieved pain. METHODS: Prospective survey of patients admitted to the emergency department of Ibn Sina teaching university hospital in Rabat (Morocco)...
2014: International Archives of Medicine
Atif Ali Hashmi, Naveen Faridi, Muhammad Muzzammil Edhi, Mehmood Khan
INTRODUCTION: Uterine tumors resembling ovarian sex cord tumors (UTROSCT) are uterine neoplasms of unknown histiogenesis which show near complete differentiation towards ovarian sex cord elements and are postulated to arise from pluripotential uterine mesenchymal cells or endometrial stromal cells with secondary sex cord differentiation. CASE PRESENTATION: A 48 year old post-menopausal women presented with abnormal uterine bleeding for which she underwent total abdominal hysterectomy with bilateral salpingo-ophorectomy...
2014: International Archives of Medicine
Anthonia O Ogbera, Olajumoke O Oshinaike, Olusola Dada, Ayodeji Brodie-Mends, Chukwuma Ekpebegh
BACKGROUND: Stroke is a major health issue in Nigeria and it is also a common cause of emergency admissions. Stroke often results in increased morbidity, mortality and reduced quality of life in people thus affected. The risk factors for stroke include metabolic abnormalities such as dyslipidaemia and diabetes mellitus (DM). The stress of an acute stroke may present with hyperglycaemia and in persons without a prior history of DM, may be a pointer to stress hyperglycaemia or undiagnosed DM...
2014: International Archives of Medicine
Hugo C van Woerden, Kathryn Ashton, Christopher Garlick, Andrew Hurley, Andrew Cooper, Alan Willson, Ray Henry, Vasiliki Kiparoglou, Christopher Potter
BACKGROUND: A web-based tool was developed and piloted by being made available to healthcare staff in Wales from September 2012 to March 2013. This evaluation included two primary outcome measures: general health and mental well-being, and six secondary outcome measures: sickness absence, alcohol use, healthy eating, smoking, physical activity and maintaining a healthy BMI. The aim was to assess the feasibility of a web-based tool to improve health behaviours in healthcare staff. METHODS: Healthcare staff joined via a website, chose two of five challenges, and recorded their health behaviours using an online tool on a regular basis...
2014: International Archives of Medicine
Damith S Liyanage, Lakmini S Pathberiya, Inuka K Gooneratne, Kumarangie K Vithanage, Ranjanie Gamage
BACKGROUND: Spinal muscular atrophies (SMAs) are a group of disorders characterized by degeneration of the anterior horn cells in the spinal cord and motor nuclei in the lower brainstem. It is transmitted by autosomal recessive inheritance and most of these conditions are linked to SMN gene. Even if the clinical picture is mainly dominated by the diffuse muscular atrophy, some patients can also show atypical clinical features such as myoclonic epilepsy ("SMA plus"), which may be related to other genes...
2014: International Archives of Medicine
Ana Márcia Dos Santos António, Marcelo Tavella Navega, Marco Aurélio Cardoso, Luiz Carlos Abreu, Vitor E Valenti
BACKGROUND: Flexible poles are tools used to provide rapid eccentric and concentric muscle contractions. It lacks in the literature studies that analyze acute cardiovascular responses in different exercises performed with this instrument. It was investigated the acute effects of exercise with flexible poles on heart period in healthy women. METHODS: The study was performed on 32 women between 18 and 25 years old. It was evaluated the heart rate variability (HRV) in the time (SDNN, RMSSD and pNN50) and frequency domain (HF, LF and LF/HF ratio)...
2014: International Archives of Medicine
Abdul Rauf Memon, Rizwan Khan, Mohammad Uzair Abdul Rauf, Kashif Shafique
Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare type of acquired hemolytic anemia that is frequently associated with thrombophilia. It may rarely present with cerebral venous sinus thrombosis, which manifests clinically with signs of raised intracranial pressure and requires lifelong anticoagulation therapy. One such rare presentation was seen in a 28 years old male who had history of recurrent episodes of passing red colored urine and this time presented with severe headache. He was diagnosed to have cerebral venous sinus thrombosis and on further workup was found to be suffering from PNH...
2014: International Archives of Medicine
João Kennedy Teixeira Lima, Sylvia Rannyelle Teixeira Lima, Antonio Leonel de Lima, Cícero Valdizébio Pereira Agra, Vitor Engrácia Valenti, Rayana Loch Gomes, Luciano Miller Rodrigues, João Antonio Correa, Rodrigo D Raimundo, Luiz Carlos de Abreu
Endocarditis is a type of infection that is common in internal medicine wards and in haemodialysis clinics. The location that is most affected are the heart valves. Herein, we report a case of an uncommon abscess, a sub-endothelial abscess between the transition of the superior vena cava and the right atrium. There were several emboli to the lung and foot, and the agent was related to Staphylococcus aureus and a double-lumen catheter. Usually, this type of abscess is located in valves, either the tricuspid valve if related to catheters or injection drug use or the mitral valve if related to other causes...
2014: International Archives of Medicine
Shazia Mumtaz, Atif Ali Hashmi, Sheema H Hasan, Muhammad Muzzammil Edhi, Mehmood Khan
INTRODUCTION: Current grading system in application by WHO/ISUP divides urothelial malignancies in low and high grade by morphologic criteria while strict segregation may become cumbersome in limited tissue specimens. As grading these carcinomas are of utmost prognostic significance after depth of invasion, therefore we evaluated the role of immunohistochemical expression of p53 and cytokeratin 20 as an adjuctive tool in grading urothelial carcinoma. METHODS: The study was conducted in Aga khan university hospital, Histopathology section from December 2010 till June 2011 for duration of six months...
2014: International Archives of Medicine
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