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Iranian Journal of Kidney Diseases

Sora Yasri, Viroj Wiwanitkit
No abstract text is available yet for this article.
May 2018: Iranian Journal of Kidney Diseases
Kourosh Goudarzipour, Farzaneh Farahmandi, Ahmad Mohammadi, Reza Taherian
Ewing sarcoma/peripheral primitive neuroectodermal tumor (ES/PNET) typically occurs in long or flat bones, soft tissues, or less often, solid organs. Ewing sarcoma/peripheral primitive neuroectodermal tumor arising from the adrenal gland is extremely rare, especially in children, and only limited cases are reported previously. Herein, we review a case of a 22-month-old girl who presented to our department with abdominal pain, bulging of the left flank, and a nonfunctioning adrenal lesion which was found to be an adrenal ES/PNET...
May 2018: Iranian Journal of Kidney Diseases
Amir Ahmad Nassiri, Legha Lotfollahi, Neda Behzadnia, Ilad Alavi Darazam, Monir Sadat Hakemi, Azam Rahimzadeh Kalaleh, Monir Kamalkhani
INTRODUCTION: Systemic arterial hypertension is prevalent in end-stage renal disease and is closely associated with left ventricular hypertrophy (LVH). Blood pressure (BP) behavior is unique in this population, and it is not clear which BP measurement should be used for treatment guidance. We aimed to evaluate the association of several methods of BP measurement with left ventricular mass index (LVMI) as hypertensive end-organ damage. MATERIALS AND METHODS: Patients on maintenance hemodialysis, 3 or 4 times per week for at least 3 months, were enrolled...
May 2018: Iranian Journal of Kidney Diseases
Xiaoxue Zhang, Ying Chen, Yamei Cai, Xing Tian, Jing Xiao, Zhanzheng Zhao, Dahai Yu
INTRODUCTION: This study aimed to assess the number and profiles of patients initializing peritoneal dialysis form the Henan Peritoneal Dialysis Registry, a provincial database in central China. MATERIALS AND METHODS: All patients aged 18 years and greater, initializing peritoneal dialysis within the province during 2007 to 2014 were included. Demographic characteristics were collected and clinical parameters included the type of renal diagnosis (primary glomerular, secondary glomerular, and others) and recorded major comorbidities in the neural, cardiovascular, respiratory, gastrointestinal, and endocrine systems...
May 2018: Iranian Journal of Kidney Diseases
Alaleh Gheissari, Rokhsareh Meamar, Amin Abedini, Peyman Roomizadeh, Mohammad Shafiei, Zahra Samaninobandegani, Zhale Tabrizi, Farhad Mahmoudi, Alireza Merrikhi, Esfandiar Najafi Tavana
INTRODUCTION: Cardiovascular disease (CVD) is the main cause of death in children with end-stage renal disease (ESRD). Matrix metalloproteinases (MMP-2 and MMP-9) are members of endopeptidases which contribute to CVD. The aim of this study was to evaluate the association of MMP-2 and MMP-9 with markers of endothelial dysfunction, soluble E-selectin and brachial flow-mediated dilatation; several biochemical risk factors of CVD; and thrombotic incidents in children with ESRD. MATERIALS AND METHODS: Thirty-one children with ESRD and 18 healthy age- and sex-adjusted controls underwent measurement of serum levels of MMP-2, MMP-9, soluble E-selectin, phosphorus, calcium, parathyroid hormone, lipid profile, thrombotic factors, and albumin...
May 2018: Iranian Journal of Kidney Diseases
Naghmeh Akbarian, Nosratollah Zarghami, Ali Mota, Sima Abediazar, Sina Abroon, Aynaz Mihanfar, Mina Amanzadeh, Akbar Darbin, Hossein Bannazadeh Baghi, Mohammad Rahmati-Yamchi
INTRODUCTION: Diabetic nephropathy is one of the serious complications of diabetes mellitus. Visfatin is an intracellular enzyme with insulin-mimicking effects. It enhances the expression of endothelial nitric oxide (NO) synthase in renal cells. This study aimed to investigate serum levels of visfatin and NO metabolites in patients with diabetic nephropathy. MATERIALS AND METHODS: A total of 80 diabetic patients were enrolled and classified into nephropathic and non-nephropathic patients...
May 2018: Iranian Journal of Kidney Diseases
Esmat Aghadavod, Alireza Soleimani, Gholamali Hamidi, Fariba Keneshlou, Akbar Heidari, Zatollah Asemi
INTRODUCTION: Patients with diabetic nephropathy (DN) may benefit from vitamin E's antilipid and antioxidant activities. This study aimed to evaluate the effects of high-dose vitamin E supplementation on markers of cardiometabolic risk and oxidative stress in patients with DN. MATERIALS AND METHODS: This randomized controlled trial was carried out on 54 patients with DN that were randomly divided into 2 groups to receive vitamin E supplement (800 IU/d) or placebo for 12 weeks...
May 2018: Iranian Journal of Kidney Diseases
Ayse Feyda Nursal, Ercan Turkmen, Suheyla Uzun Kaya, Akin Tekcan, Ozlem Sezer, Sumeyya Deniz Celik, Serbulent Yigit
INTRODUCTION: The most important complication of familial Mediterranean fever (FMF) is secondary amyloidosis, which can lead to kidney failure. Genetic variability in the genes of various components of the renin-angiotensin system may play a role in the pathogenesis of the kidney disorders.  The aim of the present study was to investigate the association between angiotensin converting enzyme (ACE) gene I/D variant and risk of developing FMF-related amyloidosis in Turkish patients. MATERIALS AND METHODS: A total of 240 individuals consisting of 40 patients with FMF-related amyloidosis, 100 FMF patients without amyloidosis, and 100 healthy controls were recruited...
May 2018: Iranian Journal of Kidney Diseases
Mahdieh Salimi, Sepehr Sarrafzadeh Zargar
INTRODUCTION: The initiation and progression of diabetic nephropathy (DN) is complex. Quantification of mRNA expression in urinary sediment cells (USCs) has emerged as a novel strategy for studying kidney diseases. Insulin requires a family of insulin receptor substrate (IRS) proteins for its physiological effects, and many reports have highlighted the role of insulin and IRS proteins in kidney physiology and disease. This study aimed to assess IRS2 expression in USCs of patients with diabetes mellitus, DN, and nondiabetic chronic kidney disease...
May 2018: Iranian Journal of Kidney Diseases
Fariba Samadian, Nooshin Dalili, Leila Mahmoudieh, Shadi Ziaei
The administration of radiocontrast media may lead to kidney injury, known as contrast-induced nephropathy, which is reversible in most cases, but its development may be associated with adverse outcomes. This review article provides recommendations for the prevention of contrast nephropathy.
May 2018: Iranian Journal of Kidney Diseases
Min Jeong Kim, Joo Hui Kim, Il Young Kim, Soo Bong Lee, In Seong Park, Mi Yeun Han, Harin Rhee, Sang Heon Song, Eun Young Seong, Ihm Soo Kwak, Dong Won Lee
Preeclampsia is the most common cause of proteinuria with hypertension during pregnancy. Primary kidney disease and kidney disease secondary to systemic disorders may rarely occur during pregnancy, resulting in proteinuria. A 34-year-old woman was admitted to our hospital with abdominal distention and lower extremity edema. The pregnancy was terminated at the 24th week of gestation due to preterm labor. Even after the delivery, proteinuria and renal deterioration continued to progress. The M-peak was not found on serum and urine protein electrophoresis...
March 2018: Iranian Journal of Kidney Diseases
Francisco E Rodríguez Castellanos, Francisco Domínguez Quintana, Virgilia Soto Abraham, Eduardo Mancilla Urrea
INTRODUCTION: Kidney transplantation is considered the ideal treatment for end-stage renal disease. Acute rejection can influence graft survival. The aim of this study was to propose a classification system for acute rejection based on factor analysis. MATERIALS AND METHODS: Data were collected from kidney transplant recipients with acute rejection diagnosis based on standard histological variables, the presence of peritubular eosinophils, and immunolabeling for lysozyme and myeloperoxidase in kidney tissue...
March 2018: Iranian Journal of Kidney Diseases
Shokoufeh Savaj, Seyedeh Ghazal Hosseini, Ahad J Ghods
INTRODUCTION: Non-human leukocyte antigen antibodies are an independent risk factor for acute rejection in kidney transplant recipients. Among them, angiotensin II receptor type 1 (ART1) antibodies can induce various effects, but their clinical importance in kidney transplant recipients has not been properly explained. This study aimed to evaluate the effect of ART1 antibodies on allograft function and hypertension in stable kidney transplant recipients. MATERIALS AND METHODS: Eighty-one kidney recipients from non- human leukocyte antigen antibodies-matched donors with stable allograft function were examined for estimated glomerular filtration rate (Chronic Kidney Disease-Epidemiology Collaboration formula) and ART1 antibodies (measured using an enzyme-linked immunosorbent assay method)...
March 2018: Iranian Journal of Kidney Diseases
Yan-Ping Wei, Xing-Gu Lin, Rong-Quan He, Juan Shen, Si-Long Sun, Gang Chen, Qiu-Yan Wang, Jian-Feng Xu, Zeng-Nan Mo
INTRODUCTION: Nonalcoholic fatty liver disease (NAFLD) has been reported to have effects on kidney diseases; however, a link between NAFLD and urinary calculi remains to be confirmed. This study was conducted on a male population based on our previous Fangchenggang Area Male Health and Examination Survey in Guangxi, China in order to estimate the frequency of urinary calculi and assess the association between NAFLD and urinary calculi while controlling for possible confounders. MATERIALS AND METHODS: This was a population-based cross-sectional study conducted in the Fangchenggang region in Guangxi, China...
March 2018: Iranian Journal of Kidney Diseases
Heba Mostafa Ahmed, Dina Ahmed Ezzat, Noha A Doudar, Mai Adel
INTRODUCTION: Early diagnosis of minimal change disease (MCD) is challenging in nephrotic children. CD80 is a protein expressed on the surface of podocytes associated with nephrotic syndrome and it is implicated in the induction of proteinuria. This study aimed to investigate the use of urinary CD80 for the diagnosis of MCD. MATERIALS AND METHODS: Urinary CD80 levels were evaluated in 36 children with nephrotic syndrome and normal glomerular filtration rate. They were divided into three groups of MCD (n = 21), focal segmental glomerulosclerosis (n = 9), and other glomerulopathies (n = 6)...
March 2018: Iranian Journal of Kidney Diseases
Zohreh Naji Ebrahimi Yazd, Sara Hosseinian, Mohammad Naser Shafei, Alireza Ebrahimzadeh Bideskan, Nazanin Entezari Heravi, Soghra Parhizgar, Samira Shahraki, Zahra Samadi Noshahr, Somayeh Mahzari, Abolfazl Khajavi Rad
INTRODUCTION: Nephropathy is an important side effect of doxorubicin. The aim of the current study was to investigate the protective effect of Plantago major extract against doxorubicin-induced functional and histological damage in rat's kidney. MATERIALS AND METHODS: Sixty Albino rats were randomly divided into 6 groups. Doxorubicin, 5 mg/kg, was injected intravenously on the 7th day of the study. Animals were treated with dexamethasone, 0.9 mg/kg, vitamin E, 100 mg/kg, and P major extract, 600 mg/kg and 1200 mg/kg, for 7 days before and 4 weeks after doxorubicin administration...
March 2018: Iranian Journal of Kidney Diseases
Li Zhou, Di Yao, Songqing Zhao, Yuzhang Jiang, Weiping Lu
INTRODUCTION: A variety of molecular pathways, such as generation of advanced glycation end products, inflammation, and oxidative stress, are involved in the development of diabetic nephropathy (DN). Recently, a protective effect of omega-3 polyunsaturated fatty acids on the kidney has been reported. This study aimed to determine serum docosahexaenoic acid (DHA) level and its association with inflammation factors in patients with DN. MATERIALS AND METHODS: One hundred patients with type 2 diabetic mellitus were divided into 3 groups of non-DN, early DN, and clinical DN, based on 24-hour urinary albumin levels...
March 2018: Iranian Journal of Kidney Diseases
Akram Ranjbar, Nejat Kheiripour, Hassan Ghasemi, Mohamad Ali Seif Rabiei, Farahnaz Dadras, Farhad Khoshjou
INTRODUCTION: Oxidative stress has a well-known role in diabetic nephropathy, and mitochondria are the major source of reactive oxygen species production. This study aimed to assess the effect of tempol, a superoxide dismutase mimetic agent, on mitochondrial antioxidant enzymes and cell viability in diabetic nephropathy. MATERIALS AND METHODS: Adult male Wistar rats were divided into 4 groups of 7 animals. Diabetes mellitus was induced by injection of streptozotocin in 2 groups, the rat in one of which were also treated with tempol for 4 weeks...
March 2018: Iranian Journal of Kidney Diseases
Shapour Badiee Aval, Yalda Ravanshad, Anoush Azarfar, Hassan Mehrad-Majd, Shatila Torabi, Sahar Ravanshad
INTRODUCTION: Uremic pruritus is characterized by an uncomfortable and unlimited sensation which leads to scratch, which strongly reduces the quality of life. Pruritus is a common symptom in patients with end-stage renal disease. Various clinical trial studies have examined the effects of acupuncture and acupressure on treatment of uremic pruritus. This systematic review meta-analysis aimed to evaluate the effectiveness based on published studies. MATERIALS AND METHODS: An electronic literature search was conducted to identify appropriate trial studies...
March 2018: Iranian Journal of Kidney Diseases
Giorgina B Piccoli, Mona Alrukhaimi, Zhi-Hong Liu, Elena Zakharova, Adeera Levin, Wkd World Kidney Day Steering Committee
Chronic kidney disease affects approximately 10% of the world's adult population; it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. The World Kidney Day and the International Women's Day coincide in 2018, thus offering an opportunity to reflect on the importance of women's health, and specifically their kidney health, on the community and the next generations, as well as to strive to be more curious about the unique aspects of kidney disease in women so that we may apply those learnings more broadly...
March 2018: Iranian Journal of Kidney Diseases
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