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Iranian Journal of Kidney Diseases

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https://www.readbyqxmd.com/read/29507277/light-chain-deposition-disease-associated-with-multiple-myeloma-developing-in-late-pregnancy
#1
Min Jeong Kim, Joo Hui Kim, Il Young Kim, Soo Bong Lee, In Seong Park, Mi Yeun Han, Harin Rhee, Sang Heon Song, Eun Young Seong, Ihm Soo Kwak, Dong Won Lee
Preeclampsia is the most common cause of proteinuria with hypertension during pregnancy. Primary kidney disease and kidney disease secondary to systemic disorders may rarely occur during pregnancy, resulting in proteinuria. A 34-year-old woman was admitted to our hospital with abdominal distention and lower extremity edema. The pregnancy was terminated at the 24th week of gestation due to preterm labor. Even after the delivery, proteinuria and renal deterioration continued to progress. The M-peak was not found on serum and urine protein electrophoresis...
March 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29507276/classification-of-acute-rejection-episodes-in-kidney-transplantation-a-proposal-based-on-factor-analysis
#2
Francisco E Rodríguez Castellanos, Francisco Domínguez Quintana, Virgilia Soto Abraham, Eduardo Mancilla Urrea
INTRODUCTION: Kidney transplantation is considered the ideal treatment for end-stage renal disease. Acute rejection can influence graft survival. The aim of this study was to propose a classification system for acute rejection based on factor analysis. MATERIALS AND METHODS: Data were collected from kidney transplant recipients with acute rejection diagnosis based on standard histological variables, the presence of peritubular eosinophils, and immunolabeling for lysozyme and myeloperoxidase in kidney tissue...
March 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29507275/effect-of-angiotensin-ii-receptor-type-1-antibodies-on-kidney-allograft-function
#3
Shokoufeh Savaj, Seyedeh Ghazal Hosseini, Ahad J Ghods
INTRODUCTION: Non-human leukocyte antigen antibodies are an independent risk factor for acute rejection in kidney transplant recipients. Among them, angiotensin II receptor type 1 (ART1) antibodies can induce various effects, but their clinical importance in kidney transplant recipients has not been properly explained. This study aimed to evaluate the effect of ART1 antibodies on allograft function and hypertension in stable kidney transplant recipients. MATERIALS AND METHODS: Eighty-one kidney recipients from non- human leukocyte antigen antibodies-matched donors with stable allograft function were examined for estimated glomerular filtration rate (Chronic Kidney Disease-Epidemiology Collaboration formula) and ART1 antibodies (measured using an enzyme-linked immunosorbent assay method)...
March 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29507274/epidemiologic-association-of-nonalcoholic-fatty-liver-disease-and-urinary-calculi-a-population-based-cross-sectional-study-in-southern-china
#4
Yan-Ping Wei, Xing-Gu Lin, Rong-Quan He, Juan Shen, Si-Long Sun, Gang Chen, Qiu-Yan Wang, Jian-Feng Xu, Zeng-Nan Mo
INTRODUCTION: Nonalcoholic fatty liver disease (NAFLD) has been reported to have effects on kidney diseases; however, a link between NAFLD and urinary calculi remains to be confirmed. This study was conducted on a male population based on our previous Fangchenggang Area Male Health and Examination Survey in Guangxi, China in order to estimate the frequency of urinary calculi and assess the association between NAFLD and urinary calculi while controlling for possible confounders. MATERIALS AND METHODS: This was a population-based cross-sectional study conducted in the Fangchenggang region in Guangxi, China...
March 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29507273/urinary-cd80-as-a-replacement-for-renal-biopsy-for-diagnosis-of-pediatric-minimal-change-disease
#5
Heba Mostafa Ahmed, Dina Ahmed Ezzat, Noha A Doudar, Mai Adel
INTRODUCTION: Early diagnosis of minimal change disease (MCD) is challenging in nephrotic children. CD80 is a protein expressed on the surface of podocytes associated with nephrotic syndrome and it is implicated in the induction of proteinuria. This study aimed to investigate the use of urinary CD80 for the diagnosis of MCD. MATERIALS AND METHODS: Urinary CD80 levels were evaluated in 36 children with nephrotic syndrome and normal glomerular filtration rate. They were divided into three groups of MCD (n = 21), focal segmental glomerulosclerosis (n = 9), and other glomerulopathies (n = 6)...
March 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29507272/protection-against-doxorubicin-induced-nephropathy-by-plantago-major-in-rat
#6
Zohreh Naji Ebrahimi Yazd, Sara Hosseinian, Mohammad Naser Shafei, Alireza Ebrahimzadeh Bideskan, Nazanin Entezari Heravi, Soghra Parhizgar, Samira Shahraki, Zahra Samadi Noshahr, Somayeh Mahzari, Abolfazl Khajavi Rad
INTRODUCTION: Nephropathy is an important side effect of doxorubicin. The aim of the current study was to investigate the protective effect of Plantago major extract against doxorubicin-induced functional and histological damage in rat's kidney. MATERIALS AND METHODS: Sixty Albino rats were randomly divided into 6 groups. Doxorubicin, 5 mg/kg, was injected intravenously on the 7th day of the study. Animals were treated with dexamethasone, 0.9 mg/kg, vitamin E, 100 mg/kg, and P major extract, 600 mg/kg and 1200 mg/kg, for 7 days before and 4 weeks after doxorubicin administration...
March 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29507271/clinical-characterization-of-serum-docosahexaenoic-acid-and-its-relationship-with-inflammation-factors-in-patients-with-diabetic-nephropathy
#7
Li Zhou, Di Yao, Songqing Zhao, Yuzhang Jiang, Weiping Lu
INTRODUCTION: A variety of molecular pathways, such as generation of advanced glycation end products, inflammation, and oxidative stress, are involved in the development of diabetic nephropathy (DN). Recently, a protective effect of omega-3 polyunsaturated fatty acids on the kidney has been reported. This study aimed to determine serum docosahexaenoic acid (DHA) level and its association with inflammation factors in patients with DN. MATERIALS AND METHODS: One hundred patients with type 2 diabetic mellitus were divided into 3 groups of non-DN, early DN, and clinical DN, based on 24-hour urinary albumin levels...
March 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29507270/antioxidative-effects-of-tempol-on-mitochondrial-dysfunction-in-diabetic-nephropathy
#8
Akram Ranjbar, Nejat Kheiripour, Hassan Ghasemi, Mohamad Ali Seif Rabiei, Farahnaz Dadras, Farhad Khoshjou
INTRODUCTION: Oxidative stress has a well-known role in diabetic nephropathy, and mitochondria are the major source of reactive oxygen species production. This study aimed to assess the effect of tempol, a superoxide dismutase mimetic agent, on mitochondrial antioxidant enzymes and cell viability in diabetic nephropathy. MATERIALS AND METHODS: Adult male Wistar rats were divided into 4 groups of 7 animals. Diabetes mellitus was induced by injection of streptozotocin in 2 groups, the rat in one of which were also treated with tempol for 4 weeks...
March 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29507269/a-systematic-review-and-meta-analysis-of-using-acupuncture-and-acupressure-for-uremic-pruritus
#9
Shapour Badiee Aval, Yalda Ravanshad, Anoush Azarfar, Hassan Mehrad-Majd, Shatila Torabi, Sahar Ravanshad
INTRODUCTION: Uremic pruritus is characterized by an uncomfortable and unlimited sensation which leads to scratch, which strongly reduces the quality of life. Pruritus is a common symptom in patients with end-stage renal disease. Various clinical trial studies have examined the effects of acupuncture and acupressure on treatment of uremic pruritus. This systematic review meta-analysis aimed to evaluate the effectiveness based on published studies. MATERIALS AND METHODS: An electronic literature search was conducted to identify appropriate trial studies...
March 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29507268/what-we-do-and-do-not-know-about-women-and-kidney-diseases-questions-unanswered-and-answers-unquestioned-reflection-on-world-kidney-day-and-international-woman-s-day
#10
EDITORIAL
Giorgina B Piccoli, Mona Alrukhaimi, Zhi-Hong Liu, Elena Zakharova, Adeera Levin, Wkd World Kidney Day Steering Committee
Chronic kidney disease affects approximately 10% of the world's adult population; it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. The World Kidney Day and the International Women's Day coincide in 2018, thus offering an opportunity to reflect on the importance of women's health, and specifically their kidney health, on the community and the next generations, as well as to strive to be more curious about the unique aspects of kidney disease in women so that we may apply those learnings more broadly...
March 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29421779/nephropathic-cystinosis-mimicking-bartter-syndrome-a-novel-mutation
#11
Funda Bastug, Hulya Nalcacioglu, Fatih Ozaltin, Emine Korkmaz, Sibel Yel
Cystinosis is a rare autosomal recessive disorder resulting from defective lysosomal transport of cystine due to mutations in the cystinosin lysosomal cystine transporter (CTNS) gene. The clinical phenotype of nephropathic cystinosis is characterized by renal tubular Fanconi syndrome and development of end-stage renal disease during the first decade. Although metabolic acidosis is the classically prominent finding of the disease, a few cases may present with hypokalemic metabolic alkalosis mimicking Bartter syndrome...
January 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29421778/prevalence-of-sarcopenia-and-dynapenia-and-their-determinants-in-iranian-peritoneal-dialysis-patients
#12
Atefeh As'habi, Iraj Najafi, Hadi Tabibi, Mehdi Hedayati
INTRODUCTION: Uremic sarcopenia and dynapenia are prevalent in chronic kidney disease patients, including dialysis patients. The present study was designed to determine the prevalence of sarcopenia and dynapenia and their determinants in peritoneal dialysis (PD) patients in Tehran, Iran. MATERIALS AND METHODS: All eligible PD patients at the peritoneal dialysis centers of Tehran were included in this cross-sectional study. Skeletal muscle mass and muscle strength were assessed using bioelectrical impedance analysis and hand grip strength, respectively...
January 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29421777/effect-of-hemodialysis-on-global-and-regional-cardiac-function-in-children-with-end-stage-renal-disease
#13
Hamid Amoozgar, Amir Naghshzan, Mitra Basiratnia, Maryam Ahmadipoor
INTRODUCTION: Changes in cardiac structure and function are common among patients with end-stage renal disease. The aim of this study was to evaluate the effect of hemodialysis on global and segmental cardiac function in children with end-stage renal disease. MATERIALS AND METHODS: Fifty-two children with ESRD who were on long-term hemodialysis at Nemazee Hospital, Shiraz, were enrolled. They underwent echocardiography (M-mode, 2-dimensional, Doppler, and speckle echocardiography) 30 minutes prior to and after hemodialysis, and the values were compared...
January 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29421776/association-between-matrix-metalloproteinase-3-activity-and-glomerular-filtration-rate-and-albuminuria-status-in-patients-with-type-2-diabetes-mellitus
#14
Mina Amanzadeh, Ali Mota, Nosratollah Zarghami, Sima Abedi-Azar, Sina Abroon, Naghmeh Akbarian, Aynaz Mihanfar, Mohammad Rahmati-Yamchi
INTRODUCTION: Diabetic nephropathy is pictured as matrix accumulation and thickening of glomerular basal membrane. Matrix metalloproteinases (MMPs) are major proteases involved in extracellular matrix degradation. Moreover, plasminogen activator inhibitor-1 (PAI-1) primarily regulates plasmin dependent proteolysis. It plays a role in renal fibrosis causing extracellular matrix accumulation through inhibition of plasmin-dependent extracellular matrix degradation. This study investigated PAI-1 serum level and MMP-3 activity and their correlation with glomerular filtration rate in patients with diabetes mellitus...
January 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29421775/increased-urine-interleukin-17-and-interleukin-22-levels-in-patients-with-candidal-urinary-tract-infection
#15
Kazem Ahmadikia, Parivash Kordbacheh, Pejman Shadpour, Sanam Nami, Abdolfattah Sarrafnejad, Mahmood Mahmoodi, Mahin Safara, Mohsen Rokni, Mohammad Yarahmadi, Shahram Mahmoudi, Mahdis Khezri, Farideh Zaini
INTRODUCTION: Candiduria is common in the hospitalized patients. This study aimed to quantify interleukin (IL)-17 and IL-22 levels in urine of candiduric patients. MATERIALS AND METHODS: A case-control study was conducted on inpatients at Hashemi Nejad Kidney Center. Thirty-four patients were identified with Candida species in their urine samples (> 103 colony-forming units per milliliter and presence of Candida species only). Urine samples with concomitant infections were excluded...
January 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29421774/efficacy-and-safety-of-rituximab-in-children-with-steroid-and-cyclosporine-resistant-and-steroid-and-cyclosporine-dependent-nephrotic-syndrome
#16
Rozita Hoseini, Kamran Sabzian, Hasan Otukesh, Nazanin Zafaranloo, Parsa Panahi, Nahid Rahimzadeh, Shahrbanoo Nakhaie, Mohsen Akhavan Sepehi
INTRODUCTION: There is evidence of the effectiveness of rituximab in treatment of nephrotic syndrome in children. The present study aimed to assess safety and the therapeutic effectiveness of rituximab in steroid- and cyclosporine-resistant pediatric nephrotic syndrome. MATERIALS AND METHODS: Forty-three children with steroid- and cyclosporine-resistant or steroid- and cyclosporine-dependent noncongenital nephrotic syndrome were included in the study to receive intravenous rituximab, 375 mg/m2/wk, for 4 weeks...
January 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29421773/study-of-urine-composition-of-patients-with-recurrent-nephrolithiasis-in-lorestan-iran
#17
Babak Hadian, Azita Zafar-Mohtashami, Fershteh Ghorbani
INTRODUCTION: Nephrolithiasis is one of the most common urinary tract diseases. After the first episode of urinary calculus, the risk of recurrence is nearly 40% to 50% at 5 years. Nephrolithiasis is a systemic disease that is associated with some metabolic disorders. This study aimed to provide a picture of the frequency of metabolic abnormalities in patients with nephrolithiasis from west part of Iran. MATERIALS AND METHODS: Patients with recurrent urinary tract calculi referred to the Nephrology-Urology Clinics in Khorramabad city were recruited...
January 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29421772/effects-of-coenzyme-q10-supplementation-on-gene-expressions-related-to-insulin-lipid-and-inflammation-pathways-in-patients-with-diabetic-nephropathy
#18
Akbar Heidari, Gholamali Hamidi, Alireza Soleimani, Esmat Aghadavod, Zatollah Asemi
INTRODUCTION: Data on the effects of coenzyme Q10 (CQ10) on gene expression related to insulin, lipid, and inflammation in patients with diabetic nephropathy (DN) are scarce. This study aimed to determine the effects of CQ10 supplementation on gene expression related to insulin, lipid, and inflammation pathways in patients with DN. MATERIALS AND METHODS: Forty patients with DN, aged 40 to 85 years old, were randomly assigned into 2 groups to receive either 100 mg/d of CQ10 supplements (n = 20) or placebo (n = 20), for 12 weeks...
January 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29421771/serum-beta-trace-protein-for-assessment-of-kidney-function-in-neonates
#19
Nastaran Khosravi, Manoochehr Asgari, Nasrin Khalessi, Rozita Hoseini, Niloofar Khosravi
INTRODUCTION: Compared to the conventional methods, serum beta-trace protein (BTP) has been shown to be more helpful for estimating glomerular filtration rate; however, its value is remained unclear in neonates. The present study aimed to investigate the range of serum BTP level in healthy term neonates and its value to estimate glomerular filtration rate. MATERIALS AND METHODS: This cross-sectional study was conducted on 50 healthy term neonates without underlying cardiovascular or kidney disorders who were admitted to Ali Asghar hospital in 2013...
January 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29421770/cystitis-cystica-glandularis-radiological-imitator-of-urothelial-carcinoma
#20
Binit Sureka, Vikas Jain, Saurabh Jain, Archana Rastogi
No abstract text is available yet for this article.
January 2018: Iranian Journal of Kidney Diseases
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