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Iranian Journal of Kidney Diseases

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https://www.readbyqxmd.com/read/29190609/nephroquiz-10-a-16-year-old-patient-with-thrombocytopenia-and-kidney-failure
#1
Maryam Ghazizadeh, Matin Ghazizadeh, Mohsen Nafar
No abstract text is available yet for this article.
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29190608/seropositivity-of-rheumatoid-arthritis-specific-tests-in-a-patient-with-nephrotic-syndrome-successful-treatment-with-rituximab
#2
Alireza Mirzaei, Yousef Ataeipoor, Mojgan Asgari, Mozhdeh Zabihiyeganeh
Presentation of rheumatoid arthritis (RA) with renal complications is very rare without articular symptoms. We here report a case of a 23-year-old woman, presenting with the edema of the extremities, no relevant previous medical history, and the features of acute tubular injury in her percutaneous kidney biopsy. Following the incidental notification of a positive rheumatoid factor test, other immunologic tests including anticyclic citrullinated peptide and antimutated citrullinated vimentin were performed, the positive results of which favored the diagnosis of RA...
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29190607/effect-of-paricalcitol-on-bone-density-after-kidney-transplantation-analysis-of-2-transplant-centers
#3
Zuzana Žilinská, Ivana Dedinská, Ján Breza, Ludovít Laca
INTRODUCTION: The Kidney Disease: Improving Global Outcomes Clinical Practice Guidelines on the management of bone disease in patients with chronic kidney disease recommend periodic measurement of serum calcium, phosphorus, vitamin D, and parathyroid hormone levels after kidney transplantation, with the frequencies that will vary according to the severity of bone disease and graft function. Paricalcitol, a selective vitamin D receptor activator, is indicated in the prevention and treatment of secondary hyperparathyroidism...
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29190606/association-between-klotho-gene-polymorphism-and-markers-of-bone-metabolism-in-patients-receiving-maintenance-hemodialysis-in-iran
#4
Aboalfazl Nazarian, Meisam Hasankhani, Monireh Aghajany-Nasab, Ali Monfared
INTRODUCTION: Some genetic variations of Klotho have been reported as a risk factor for calcification and hyperphosphatemia in chronic kidney disease. Klotho polymorphism is also associated with outcome in patients receiving hemodialysis. This study aimed to evaluate the relationship between Klotho single nucleotide polymorphism (SNP) and bone metabolism as an early prognostic measure for chronic kidney disease.   Materials and Methods. Sixty patients receiving hemodialysis and 60 age-matched controls were enrolled in the study of the assessment of 2 types of Klotho polymorphism (G395A and C1818T)...
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29190605/evaluation-of-renal-toxicity-of-colistin-therapy-with-neutrophil-gelatinase-associated-lipocalin-a-biomarker-of-renal-tubular-damage
#5
Atefeh Ordooei Javan, Jamshid Salamzadeh, Shervin Shokouhi, Zahra Sahraei
INTRODUCTION: Nephrotoxicity has been a concern with new dosing regimens of colistin. This study was designed to compare nephrotoxicity of high dose and conventional dose of colistin and the ability of detecting it using neutrophil gelatinase-associated lipocalin (NGAL). MATERIALS AND METHODS: A randomized clinical trial was carried out on 40 patients with multidrug-resistant gram-negative infections assigned into 2 groups to receive high and conventional doses of colistin...
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29190604/metabolic-response-to-mulberry-extract-supplementation-in-patients-with-diabetic-nephropathy-a-randomized-controlled-trial
#6
Mohsen Taghizadeh, Alireza Soleimani, Fereshteh Bahmani, Alireza Moravveji, Amir Asadi, Elahe Amirani, Narjes Farzin, Nasrin Sharifi, Afshin Naseri, Majid Dastorani, Zatollah Asemi
INTRODUCTION: This study aimed to evaluate the effects of mulberry extract administration on markers of insulin metabolism, lipid concentrations, and biomarkers of inflammation and oxidative stress in patients with diabetic nephropathy (DN). MATERIALS AND METHODS: Sixty patients were randomly allocated into 2 groups to receive either 300 mg/d of mulberry extract (n = 30) or placebo (n = 30), twice per day for 12 weeks. Fasting blood samples were taken at the onset of the study and 12 weeks after supplementation to examine markers of insulin metabolism, lipid concentrations, and biomarkers of inflammation and oxidative stress...
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29190603/upregulation-of-cabin1-during-injury-to-renal-tubular-epithelial-cells-in-rats
#7
Yueqiang Wen, Huiyuan Li, Peilan Zhou, Lingling Liu, Zebin Wang, Jianbo Liang
INTRODUCTION: Calcineurin-binding protein 1 (Cabin1) interacts with calcineurin and p53, but its function in renal tubular epithelial cell (RTEC) is unclear. We established 5/6 nephrectomized rats and angiotensin II-induced injury to the RTECs in vitro, to observe the expression of Cabin1 during RTEC injury. MATERIALS AND METHODS: Sprague-Dawley rats were sacrificed at 4 and 8 weeks after 5/6 nephrectomy. Renal pathology and mitochondrial damage were detected by light and electrical microscope...
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29190602/protective-effects-of-pomegranate-juice-on-nephrotoxicity-induced-by-captopril-and-gentamicin-in-rats
#8
Abbas Alimoradian, Saeed Changizi-Ashtiyani, Atefeh Ghiasabadi Farahani, Leila Kheder, Razie Rajabi, Akram Sharifi
INTRODUCTION: Nephrotoxicity is an important side effects of captopril and gentamicin. This study investigated the prophylactic and protective effects of pomegranate juice (PJ) on the kidney exposed to nephrotoxicity induced by these medications. MATERIALS AND METHODS: Wistar male rats received drinking water (groups 1 to 3) or PJ at doses of 4 mL/kg (group 4), 10 mL/kg (groups 5 and 7), and 15 mL/kg (group 6) for 14 days. Captopril and gentamicin were administrated on days 10 and 14 to groups 1 and 2, respectively, while groups 3 to 6 received both...
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29190601/cytokine-gene-polymorphism-in-children-with-idiopathic-nephrotic-syndrome
#9
Dina Abdel Razek Midan, Nesreen Gamal Elhelbawy, Mona Salah El-Din Habib, Iman Aly Ahmedy, Rasha Ibrahim Noreldin
INTRODUCTION: Idiopathic nephrotic syndrome (INS) is a glomerular disease with completely unclear pathogenesis and different responses to steroid therapy. This study aimed to investigate the role of cytokine genes promoter polymorphisms in steroid therapy responses. MATERIALS AND METHODS: One hundred children with INS and 30 healthy controls were studied. Genotyping of TNF-α-G308A single nucleotide polymorphism was done using polymerase chain reaction-restriction fragment length polymorphism method, while of IL-6-G174C single nucleotide polymorphism was done using real-time polymerase chain reaction...
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29190600/hyaluronic-acid-as-a-new-biomarker-to-differentiate-acute-kidney-injury-from-chronic-kidney-disease
#10
Davut Akin, Sehmus Ozmen, Mehmet Emin Yilmaz
INTRODUCTION: It may be difficult to differentiate acute kidney injury from chronic kidney disease in patients with no past medical reports of kidney function. This study aimed to investigate the role of serum hyaluronic acid (HA), which is known as a marker of fibrosis, in differential diagnosis of kidney failure. MATERIALS AND METHODS: A total of 90 patients (52 women and 38 mne) admitted to our renal unit with uremia for the first time were included. Serum HA level was measured...
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29190599/irreversible-lesions-of-tacrolimus-induced-posterior-reversible-leukoencephalopathy-syndrome
#11
Shokoufeh Savaj, Maryam Farasatinasab, Atefeh Amouzegar
No abstract text is available yet for this article.
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29190598/evaluation-and-management-of-kidney-calculi
#12
Arash Shadman, Bahar Bastani
INTRODUCTION: The recent change in the view towards nephrolithiasis from a benign isolated disease to a disorder associated with numerous systemic and chronic conditions has added to the importance of a more thorough and timely diagnostic and therapeutic intervention. MATERIALS AND METHODS: Both original and review articles found via the PubMed search on recent evaluation and management strategies of urinary calculi were reviewed. These resources were integrated with the authors' knowledge of the field...
November 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29038398/notice-of-inadvertent-duplicate-publication-and-retraction
#13
(no author information available yet)
No abstract text is available yet for this article.
October 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29038397/errata
#14
(no author information available yet)
No abstract text is available yet for this article.
October 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29038396/multiple-myeloma-in-a-patient-with-familial-mediterranean-fever
#15
Bahman Bashardoust, Nasrollah Maleki
Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent episodes of painful inflammation in the abdomen, chest, or joints. The coexistence of multiple myeloma (MM) and FMF is an extremely rare event. Here, we report a case of FMF with concurrent MM. A 63-year-old woman was diagnosed with FMF since 15 years earlier. She was admitted with a complaint of low back pain. Regarding the presence of back pain, anemia, hypercalcemia, and kidney failure, a diagnosis of MM was suspected...
October 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29038395/acute-interstitial-nephritis-induced-by-citrullus-colocynthis
#16
Shokoufeh Savaj, Mohammad Ghaffari, Mohammad Amin Abbasi, Javad Azar
Acute interstitial nephritis (AIN) is known as a common cause of acute kidney injury, found in 15% to 27% of kidney biopsies. Drug-induced AIN is currently the most common cause of AIN. The most common medications causing AIN are antibiotics and nonsteroidal anti-inflammatory drugs. We describe a case of Citrullus colocynthis (herbal remedy for diabetes mellitus and weight reduction) that induced AIN. A 31-year-old woman with major thalassemia, diabetes mellitus, and hepatitis C infection was admitted because of flank pain and unexpected increase in serum creatinine level...
October 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29038394/factors-associated-with-lumbar-and-femoral-bone-mineral-density-in-kidney-transplants-candidates
#17
Mohammad Aghighi, Mitra Mahdavi Mazdeh, Mohsen Nafar, Vahid Rakhshan
INTRODUCTION: Data on risk factors associated with low bone mineral density are limited in patients with end-stage renal disease. This study evaluated the factors deemed associated with lumbar and femoral Z and T scores. MATERIALS AND METHODS: Clinical and demographic data of 98 patients waiting for kidney transplantation were collected, as well as lumbar and femoral bone densitometries, before transplantation. Osteoporosis and osteopenia and factors associated with bone mineral density were assessed...
October 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29038393/association-of-body-mass-index-waist-circumference-and-waist-stature-ratio-with-urine-composition-in-patients-with-urolithiasis
#18
Sanaz Tavasoli, Maryam Taheri, Alireza Khoshdel, Abbas Basiri
INTRODUCTION: This study was aimed to evaluate the correlation of body mass index (BMI), waist circumference (WC), and waist-stature ratio (WSR) with urinary composition in urolithiasis patients. MATERIALS AND METHODS: Medical reports of 1410 urolithiasis patients referred to a tertiary in Tehran, from 2010 to 2015, were reviewed. Collected data included WC, BMI, and WSR, 24-hour urine composition, and the first-morning urine pH. Urinary relative supersaturation of calcium oxalate, calcium phosphate, and uric acid were calculated...
October 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29038392/urine-vancomycin-level-as-a-method-for-drug-monitoring-in-patients-with-normal-and-decreased-kidney-function
#19
Shervin Shokouhi, Ilad Alavi Darazam, Ziba Ayoubian, Mohammad M Sajadi
INTRODUCTION: Therapeutic drug monitoring of vancomycin is an important issue in clinical decision-making and dosage modifying, particularly among patients in critical conditions and decreased kidney function. Urine is typically readily available in hospitalized patients and therapeutic drug monitoring in urine may be a reliable and noninvasive procedure compared to frequent blood sampling. We aimed to determine and validate the diagnostic yield of vancomycin trough level in urine. MATERIALS AND METHODS: In a prospective study, 95 patients who were treated with vancomycin for any clinical condition were enrolled in this study...
October 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29038391/embryohistiogenesis-of-vascular-tufts-of-glomeruli-a-possible-hypothesis
#20
Shahriar Dabiri, Mohammad Mehdi Moeini-Aghtaei, Bahram Dabiri
INTRODUCTION: Embryogenesis of the kidney glomeruli, especially its vascular component, has not been well documented. Glomeruli capillary tuft is surrounded and enveloped by visceral epithelial cells, which is a unique portal system that connects afferent with efferent arteriole without interaction with venular circulation. We hypothesized that the portal system embryologically has developed by extension of the intima of afferent arteriole into the stroma of glomerulus. We also hypothesized that juxtaglomeruli apparatus was developed from remnants of smooth muscle cells of the media of afferent arteriole at the anastomosing site with the Bowman capsule entrance...
October 2017: Iranian Journal of Kidney Diseases
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