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BMC Proceedings

Paulo P Andrade, Marília Andreza da Silva Ferreira, Marta Silva Muniz, Amaro de Casto Lira-Neto
The emergence of new technologies for genetic modification has broadened the range of possible new products. The regulations of many countries that could benefit from these new products may not be prepared to assess risks and enable science-based decision-making. This is especially acute in the case of genetically modified insects with potential use in public health and agriculture. Modifications of the regulatory framework, sometimes necessary to allow a proper risk assessment of products from new technologies, are strongly influenced by political decisions derived from the balance of power and interest among stakeholders...
2018: BMC Proceedings
Andrew Stirling, K R Hayes, Jason Delborne
Frameworks that govern the development and application of novel products, such as the products of synthetic biology, should involve all those who are interested or potentially affected by the products. The governance arrangements for novel products should also provide a democratic mechanism that allows affected parties to express their opinions on the direction that innovation does or does not take. In this paper we examine rationales, obstacles and opportunities for public participation in governance of novel synthetic biology products...
2018: BMC Proceedings
Vibha Ahuja
In India, genetically modified organisms (GMOs) and the products thereof are regulated under the "Rules for the manufacture, use, import, export & storage of hazardous microorganisms, genetically engineered organisms or cells, 1989" (referred to as Rules, 1989) notified under the Environment (Protection) Act, 1986. These Rules are implemented by the Ministry of Environment, Forest and Climate Change, Department of Biotechnology and State Governments though six competent authorities. The Rules, 1989 are supported by series of guidelines on contained research, biologics, confined field trials, food safety assessment, environmental risk assessment etc...
2018: BMC Proceedings
Geoff Turner, Camilla Beech, Lucia Roda
The development and use of genetic technologies is regulated by countries according to their national laws and governance structures. Legal frameworks require comprehensive technical evidence to be submitted by an applicant on the biology of the organism, its safety to human, animal health and the environment in which it will be released. Some countries also require information on socio-economic and trade impacts. One of the key elements that assists decision-making under those legal frameworks is the use of risk assessments...
2018: BMC Proceedings
Michael M Burgess, John D Mumford, James V Lavery
Policy and management related to the release of organisms generated by emerging biotechnologies for pest management should be informed through public engagement. Regulatory decisions can be conceptually distinguished into the development of frameworks, the assessment of the release of a specific modified organism, and implementation decisions such as location and timing. Although these decisions are often intertwined in practice, the negotiation takes place at different stages of technology development and suggests different roles for public engagement...
2018: BMC Proceedings
Barbara Glover, Olalekan Akinbo, Moussa Savadogo, Samuel Timpo, Godwin Lemgo, Woldeyesus Sinebo, Sunday Akile, Silas Obukosia, Jeremy Ouedraogo, Margareth Ndomondo-Sigonda, Muffy Koch, Diran Makinde, Aggrey Ambali
The New Partnership for Africa's Development (NEPAD) Agency recognizes that Africa is in a period of transition and that this demands exploring and harnessing safe advances made in science-based innovations including modern biotechnology. To advance the science of biotechnology in Africa effectively, while at the same time safeguarding human health and the environment, the African Union (AU) adopted a High-Level Panel report on modern biotechnology entitled, Freedom to Innovate , which advocated for a coevolutionary approach where technology development goes hand in hand with regulation...
2018: BMC Proceedings
James P Collins
Gene drives are systems of biased inheritance that enhance the likelihood a sequence of DNA passes between generations through sexual reproduction and potentially throughout a local population and ultimately all connected populations of a species. Gaps in our knowledge of gene drive systems prompted the US National Institutes of Health (NIH) and the Foundation for the NIH to ask the US National Academies of Sciences, Engineering, and Medicine (NASEM) to convene an expert panel to provide an independent, objective examination of what we know about gene drive systems...
2018: BMC Proceedings
LaVerne L Brown, Barbara Cohen, Derrick Tabor, Giovanna Zappalà, Padma Maruvada, Paul M Coates
The Office of Dietary Supplements, the National Institute on Minority Health and Health Disparities, the National Institute on Aging, and the National Institute of Diabetes and Digestive and Kidney Diseases, all components of the U.S. National Institutes of Health, co-sponsored an expert panel meeting to discuss the vitamin D paradox in Black Americans. The paradox is that despite markedly low (or "deficient") measures of vitamin D status in Black Americans, the incidence of falls, fractures, or osteopenia are significantly lower compared to White American counterparts with similar vitamin D status...
2018: BMC Proceedings
Jill Thompson, Chi-Chi Undie, Avni Amin, Brooke Ronald Johnson, Rajat Khosla, Leopold Ouedraogo, Triphonie Nkurunziza, Sara Rich, Elizabeth Westley, Melissa Garcia, Harriet Birungi, Ian Askew
In April 2016, the Population Council, in partnership with the World Health Organization (WHO) and the International Consortium for Emergency Contraception, convened a regional meeting in Lusaka, Zambia, geared toward supporting countries in East and Southern Africa in meeting their obligations under the Maputo Protocol. These obligations include expanding access to women's reproductive health services - especially women survivors of sexual violence. Government and civil society representatives from six countries participated: Botswana, Ethiopia, Kenya, Malawi, Rwanda, and Zambia...
2018: BMC Proceedings
Nicola S Pocock, Rapeepong Suphanchaimat, Chee Khoon Chan, Erwin Martinez Faller, Nicholas Harrigan, Veena Pillai, Kolitha Wickramage
Migrants and refugees face challenges accessing both healthcare and good social determinants of health in Malaysia. Participants at the "Migrant and Refugee Health in Malaysia workshop, Kuala Lumpur, 9-10 November 2017" scoped these challenges within the regional ASEAN context, identifying gaps in knowledge and practical steps forward to improve the evidence base in the Malaysia.
2018: BMC Proceedings
Martin Okechukwu C Ota, Doris Gatwiri Kirigia, Emil Asamoah-Odei, Pamela Suzanne Drameh-Avognon, Olushayo Olu, Mwelecele Ntuli Malecela, Joseph Waogodo Cabore, Matshidiso Rebecca Moeti
Background: Universal Health Coverage (UHC)is central to the health Sustainable Development Goals(SDG). Working towards UHC is a powerful mechanism for achieving the right to health and promoting human development which is a priority area of focus for the World Health Organization WHO. As a result, the WHO Regional Office for Africa convened the first-ever Africa Health Forum, co- hosted by the government of Rwanda in Kigali in June 2017 with the theme "Putting People First: The Road to Universal Health Coverage in Africa"...
2018: BMC Proceedings
Jill Thompson, Chi-Chi Undie, Avni Amin, Brooke Ronald Johnson, Rajat Khosla, Leopold Ouedraogo, Triphonie Nkurunziza, Sarah Rich, Elizabeth Westley, Melissa Garcia, Harriet Birungi, Ian Askew
[This corrects the article DOI: 10.1186/s12919-018-0101-5.].
2018: BMC Proceedings
Florian Halbeisen, Claire Hogg, Mikkel C Alanin, Zuzanna Bukowy-Bieryllo, Francisco Dasi, Julie Duncan, Amanda Friend, Myrofora Goutaki, Claire Jackson, Victoria Keenan, Amanda Harris, Robert A Hirst, Philipp Latzin, Gemma Marsh, Kim Nielsen, Dominic Norris, Daniel Pellicer, Ana Reula, Bruna Rubbo, Nisreen Rumman, Amelia Shoemark, Woolf T Walker, Claudia E Kuehni, Jane S Lucas
Primary ciliary dyskinesia (PCD) is a rare heterogenous condition that causes progressive suppurative lung disease, chronic rhinosinusitis, chronic otitis media, infertility and abnormal situs. 'Better Experimental Approaches to Treat Primary Ciliary Dyskinesia' (BEAT-PCD) is a network of scientists and clinicians coordinating research from basic science through to clinical care with the intention of developing treatments and diagnostics that lead to improved long-term outcomes for patients. BEAT-PCD activities are supported by EU funded COST Action (BM1407)...
2018: BMC Proceedings
Maryam Foroozesh, Marguerite Giguette, Kathleen Morgan, Kelly Johanson, Gene D'Amour, Tiera Coston, Clair Wilkins-Green
Background and purpose: Xavier University of Louisiana is a historically Black and Catholic university that is nationally recognized for its science, technology, engineering and mathematics (STEM) curricula. Approximately 73% of Xavier's students are African American, and about 77% major in the biomedical sciences. Xavier is a national leader in the number of STEM majors who go on to receive M.D. degrees and Ph.D. degrees in science and engineering. Despite Xavier's advances in this area, African Americans still earn about 7...
2017: BMC Proceedings
Heather E McCreath, Keith C Norris, Nancy E Calderόn, Dawn L Purnell, Nicole M G Maccalla, Teresa E Seeman
Background: The National Institutes of Health (NIH)-funded Diversity Program Consortium (DPC) includes a Coordination and Evaluation Center (CEC) to conduct a longitudinal evaluation of the two signature, national NIH initiatives - the Building Infrastructure Leading to Diversity (BUILD) and the National Research Mentoring Network (NRMN) programs - designed to promote diversity in the NIH-funded biomedical, behavioral, clinical, and social sciences research workforce. Evaluation is central to understanding the impact of the consortium activities...
2017: BMC Proceedings
Guido G Urizar, Laura Henriques, Chi-Ah Chun, Paul Buonora, Kim-Phuong L Vu, Gino Galvez, Laura Kingsford
Background and purpose: First-generation college graduates, racial and ethnic minorities, people with disabilities, and those from disadvantaged backgrounds are gravely underrepresented in the health research workforce representing behavioral health sciences and biomedical sciences and engineering (BHS/BSE). Furthermore, relative to their peers, very few students from these underrepresented groups (URGs) earn scientific bachelor's degrees with even fewer earning doctorate degrees. Therefore, programs that engage and retain URGs in health-related research careers early on in their career path are imperative to promote the diversity of well-trained research scientists who have the ability to address the nation's complex health challenges in an interdisciplinary way...
2017: BMC Proceedings
Mica Estrada, Alegra Eroy-Reveles, Avi Ben-Zeev, Teaster Baird, Carmen Domingo, Cynthia A Gómez, Kirsten Bibbins-Domingo, Audrey Parangan-Smith, Leticia Márquez-Magaña
Background: The underrepresentation of minority students in the sciences constrains innovation and productivity in the U.S. The SF BUILD project mission is to remove barriers to diversity by taking a "fix the institution" approach rather than a "fix the student" one. SF BUILD is transforming education, research, training, and mentoring at San Francisco State University, a premiere public university that primarily serves undergraduates and ethnic minority students. It boasts a large number of faculty members from underrepresented groups (URGs), including many of the project leaders...
2017: BMC Proceedings
William R LaCourse, Kathy Lee Sutphin, Laura E Ott, Kenneth I Maton, Patrice McDermott, Charles Bieberich, Philip Farabaugh, Philip Rous
Background: UMBC, a diverse public research university, "builds" upon its reputation in producing highly capable undergraduate scholars to create a comprehensive new model, STEM BUILD at UMBC. This program is designed to help more students develop the skills, experience and motivation to excel in science, technology, engineering, and mathematics (STEM). This article provides an in-depth description of STEM BUILD at UMBC and provides the context of this initiative within UMBC's vision and mission...
2017: BMC Proceedings
Jeanne M Andreoli, Andrew Feig, Steven Chang, Sally Welch, Ambika Mathur, Gary Kuleck
Background and purpose: Faced with decades of severe economic decline, the city of Detroit, Michigan (USA) is on the cusp or reinventing itself. A Consortium was formed of three higher education institutions that have an established mission to serve an urban population and a vested interest in the revitalization of the health, welfare, and economic opportunity in the Detroit metro region that is synergistic with national goals to diversify the biomedical workforce. The purpose of this article is to describe the rationale, approach, and model of the Research Enhancement for BUILDing Detroit (ReBUILDetroit) Consortium, as a cross-campus collaborative for students, faculty, and institutional development...
2017: BMC Proceedings
Christine A Sorkness, Christine Pfund, Elizabeth O Ofili, Kolawole S Okuyemi, Jamboor K Vishwanatha, Maria Elena Zavala, Theresa Pesavento, Mary Fernandez, Anthony Tissera, Alp Deveci, Damaris Javier, Alexis Short, Paige Cooper, Harlan Jones, Spero Manson, Dedra Buchwald, Kristin Eide, Andrea Gouldy, Erin Kelly, Nicole Langford, Richard McGee, Clifford Steer, Thad Unold, Anne Marie Weber-Main, Adriana Báez, Jonathan Stiles, Priscilla Pemu, Winston Thompson, Judith Gwathmey, Kimberly Lawson, Japera Johnson, Meldra Hall, Douglas Paulsen, Mona Fouad, Ann Smith, Rafael Luna, Donald Wilson, Greg Adelsberger, Drew Simenson, Abby Cook, Monica Feliu-Mojer, Eileen Harwood, Amy Jones, Janet Branchaw, Stephen Thomas, Amanda Butz, Angela Byars-Winston, Stephanie House, Melissa McDaniels, Sandra Quinn, Jenna Rogers, Kim Spencer, Emily Utzerath, Duplicate Of Weber-Main, Veronica Womack
Background and purpose: Effective mentorship is critical to the success of early stage investigators, and has been linked to enhanced mentee productivity, self-efficacy, and career satisfaction. The mission of the National Research Mentoring Network (NRMN) is to provide all trainees across the biomedical, behavioral, clinical, and social sciences with evidence-based mentorship and professional development programming that emphasizes the benefits and challenges of diversity, inclusivity, and culture within mentoring relationships, and more broadly the research workforce...
2017: BMC Proceedings
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