journal
MENU ▼
Read by QxMD icon Read
search

Gut and Liver

journal
https://www.readbyqxmd.com/read/27980231/a-novel-model-for-predicting-hepatocellular-carcinoma-development-in-patients-with-chronic-hepatitis-b-and-normal-alanine-aminotransferase-levels
#1
Dong Hyun Sinn, Jeong-Hoon Lee, Kyunga Kim, Joong Hyun Ahn, Ji Hyeon Lee, Jung Hee Kim, Dong Hyeon Lee, Jung-Hwan Yoon, Wonseok Kang, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik
Background/Aims: Hepatocellular carcinoma (HCC) can develop in chronic hepatitis B (CHB) patients with normal alanine aminotransferase (ALT) levels. Therefore, methods that can stratify an individual's HCC risk are needed. Methods: A simple HCC risk score was developed from 971 patients with CHB who had elevated hepatitis B virus DNA levels (>2,000 IU/mL) with normal or mildly elevated ALT levels (<80 U/L). The score was validated from an independent cohort of 507 patients...
December 16, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27965478/efficacy-of-capecitabine-plus-oxaliplatin-combination-chemotherapy-for-advanced-pancreatic-cancer-after-failure-of-first-line-gemcitabine-based-therapy
#2
Kwang Hyun Chung, Ji Kon Ryu, Jun Hyuk Son, Jae Woo Lee, Dong Kee Jang, Sang Hyub Lee, Yong-Tae Kim
Background/Aims: Second-line chemotherapy in patients with advanced pancreatic ductal adenocarcinoma (PDAC) that progresses following gemcitabine-based treatment has not been established. This study aimed to investigate the efficacy and safety of second-line combination chemotherapy with capecitabine and oxaliplatin (XELOX) in these patients. Methods: Between August 2011 and May 2014, all patients who received at least one cycle of XELOX (capecitabine, 1,000 mg/m(2) twice daily for 14 days; oxaliplatin, 130 mg/m(2) on day 1 of a 3-week cycle) combination chemotherapy for unresectable or recurrent PDAC were retrospectively recruited...
December 16, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27965477/impact-of-obesity-on-a-chinese-population-with-erosive-esophagitis-and-barrett-s-esophagus
#3
Shou-Wu Lee, Han-Chung Lien, Teng-Yu Lee, Chun-Fang Tung, Hong-Zen Yeh, Chi-Sen Chang
Background/Aims: The aim of this study was to investigate the associations between obesity and erosive esophagitis (EE) or Barrett's esophagus (BE) in a Chinese population. Methods: Data from subjects were retrospectively collected from 2006 to 2009. Individuals with BE were identified and age- and sex-matched at a 1:2 ratio with normal esophagocardial junction and EE patients. The subjects were stratified into two groups: the normal weight group and overweight/ obesity group (body mass index ≥25 mg/m(2)) or the normal waist group and abdominal obesity group (waist circumference ≥90 cm for men and ≥80 cm for women)...
December 16, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27965476/positive-glucose-breath-tests-in-patients-with-hysterectomy-gastrectomy-and-cholecystectomy
#4
Dae Bum Kim, Chang-Nyol Paik, Yeon Ji Kim, Ji Min Lee, Kyong-Hwa Jun, Woo Chul Chung, Kang-Moon Lee, Jin-Mo Yang, Myung-Gyu Choi
Background/Aims: This study aimed to investigate the prevalence and characteristics of small intestinal bacterial overgrowth (SIBO) in patients undergoing abdominal surgeries, such as gastrectomy, cholecystectomy, and hysterectomy. Methods: One hundred seventy-one patients with surgery (50 hysterectomy, 14 gastrectomy, and 107 cholecystectomy), 665 patients with functional gastrointestinal disease (FGID) and 30 healthy controls undergoing a hydrogen (H₂)-methane (CH₄) glucose breath test (GBT) were reviewed...
December 16, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27965475/magnetic-resonance-elastography-and-diffusion-weighted-imaging-in-the-evaluation-of-hepatic-fibrosis-in-chronic-hepatitis-b
#5
Tiffany P Hennedige, Gang Wang, Fiona P Leung, Hind S Alsaif, Lynette Ls Teo, Seng Gee Lim, Aileen Wee, Sudhakar K Venkatesh
Background/Aims: Comparison of the accuracy of magnetic resonance elastography (MRE) and diffusion weighted imaging (DWI) for the diagnosis of liver fibrosis in patients with chronic hepatitis B (CHB). Methods: In this retrospective analysis, we investigated 63 patients with CHB and liver fibrosis. DWI was performed with both breath-hold (DWI-BH) and free-breathing (DWI-FB) sequences (b=0, 500). The mean liver stiffness and apparent diffusion coefficient (ADC) were calculated by drawing regions of interest maps...
December 16, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27965474/a%C3%A3-a%C3%A3-berries-inhibit-colon-tumorigenesis-in-azoxymethane-dextran-sulfate-sodium-treated-mice
#6
Yoon Jin Choi, Yoon Jeong Choi, Nayoung Kim, Ryoung Hee Nam, Seonmin Lee, Hye Seung Lee, Ha-Na Lee, Young-Joon Surh, Dong Ho Lee
Background/Aims: The aim of this study was to investigate the protective effect of açaí against azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colorectal cancer development. Methods: The effect of açaí on tumorigenesis was assessed by evaluating tumor incidence, multiplicity and invasiveness in the mouse colon. The levels of myeloperoxidase (MPO) and proinflammatory cytokines (tumor necrosis factor α [TNF-α], interleukin [IL]-1β, and IL-6) were measured via enzyme-linked immunosorbent assay...
December 16, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27965473/diagnostic-value-of-endoscopic-ultrasonography-in-symptomatic-patients-with-high-and-intermediate-probabilities-of-common-bile-duct-stones-and-a-negative-computed-tomography-scan
#7
Tae Joo Jeon, Jae Hee Cho, Yeon Suk Kim, Si Young Song, Ji Young Park
Background/Aims: When computed tomography (CT) does not indicate choledocholithiasis in highly suspicious patients, there is no definite consensus on the subsequent modality. Endoscopic ultrasonography (EUS) indicates fewer procedure-related complications than endoscopic retrograde cholangiopancreatography (ERCP) and has a lower cost than magnetic resonance cholangiopancreatography. Therefore, we aimed to investigate the diagnostic value of EUS in patients with suspected choledocholithiasis and negative CT findings...
December 16, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27928095/cholangiocarcinoma-current-knowledge-and-new-developments
#8
REVIEW
Boris Blechacz
Cholangiocarcinoma (CCA) is the second most common primary malignancy. Although it is more common in Asia, its incidence in Europe and North America has significantly increased in recent decades. The prognosis of CCA is dismal. Surgery is the only potentially curative treatment, but the majority of patients present with advanced stage disease, and recurrence after resection is common. Over the last two decades, our understanding of the molecular biology of this malignancy has increased tremendously, diagnostic techniques have evolved, and novel therapeutic approaches have been established...
December 8, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27890867/obesity-related-digestive-diseases-and-their-pathophysiology
#9
REVIEW
Su Youn Nam
Obesity is a growing medical and public health problem worldwide. Many digestive diseases are related to obesity. In this article, the current state of our knowledge of obesity-related digestive diseases, their pathogenesis, and the medical and metabolic consequences of weight reduction are discussed. Obesity-related digestive diseases include gastroesophageal reflux disease, Barrett's esophagus, esophageal cancer, colon polyp and cancer, nonalcoholic fatty liver disease, hepatitis C-related disease, hepatocellular carcinoma, gallstone, cholangiocarcinoma, and pancreatic cancer...
November 29, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27885175/cpg-island-methylator-phenotype-high-colorectal-cancers-and-their-prognostic-implications-and-relationships-with-the-serrated-neoplasia-pathway
#10
REVIEW
Ye-Young Rhee, Kyung-Ju Kim, Gyeong Hoon Kang
The concept of a CpG island methylator phenotype (CIMP) was first introduced by Toyota and Issa to describe a subset of colorectal cancers (CRCs) with concurrent hypermethylation of multiple CpG island loci. The concept of CIMP as a molecular carcinogenesis mechanism was consolidated by the identification of the serrated neoplasia pathway, in which CIMP participates in the initiation and progression of serrated adenomas. Distinct clinicopathological and molecular features of CIMP-high (CIMP-H) CRCs have been characterized, including proximal colon location, older age of onset, female preponderance, and frequent associations of high-level microsatellite instability and BRAF mutations...
November 28, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27876707/critical-appraisal-of-association-between-diet-and-lifestyle-habits-and-irritable-bowel-syndrome-a-case-control-study
#11
LETTER
Samantha Noseworthy
No abstract text is available yet for this article.
November 24, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27876706/reply-the-characteristics-about-our-study-in-irritable-bowel-syndrome
#12
LETTER
Kang-Min Zhuang, Yu-Bin Guo, Si-De Liu
No abstract text is available yet for this article.
November 24, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27843131/adsorptive-granulocyte-and-monocyte-apheresis-in-the-treatment-of-ulcerative-colitis-the-first-multicenter-study-in-china
#13
Ya-Min Lai, Wei-Yan Yao, Yao He, Xuan Jiang, Yu-Bei Gu, Min-Hu Chen, Yu-Lan Liu, Yao-Zong Yuan, Jia-Ming Qian
Background/Aims: Patients with active ulcerative colitis (UC) have elevated levels of activated myeloid-derived leukocytes as a source of inflammatory cytokines. The selective depletion of these leukocytes by adsorptive granulocyte/monocyte apheresis (GMA) with an Adacolumn should alleviate inflammation, promote remission and enhance drug efficacy. However, studies have reported contrasting efficacy outcomes based on patients' baseline demographic variables. This study was undertaken to understand the demographic features of GMA responders and nonresponders...
November 16, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27840367/diagnostic-yield-and-clinical-impact-of-video-capsule-endoscopy-in-patients-with-chronic-diarrhea-a-korean-multicenter-capentry-study
#14
Hyun Joo Song, Jeong Seop Moon, Seong Ran Jeon, Jin-Oh Kim, Jinsu Kim, Dae Young Cheung, Myung-Gyu Choi, Yun Jeong Lim, Ki-Nam Shim, Byong Duk Ye, Jae Hee Cheon, Cheol Hee Park, Hyun-Soo Kim, Ji Hyun Kim, Dong Kyung Chang, Jae Hyuk Do, Kyeong Ok Kim, Byung Ik Jang, Sung-Jae Shin
Background/Aims: In some cases, chronic diarrhea is unexplained, and small bowel disorders may be one of the causes. The aim of this study was to assess the diagnostic yield and clinical impact of video capsule endoscopy (VCE) in patients with chronic diarrhea. Methods: We retrospectively analyzed records from October 2002 to August 2013 in the VCE nationwide database registry (n=2,964). Ninety-one patients from 15 medical centers (60 males and 31 females; mean age, 47±19 years) were evaluated for VCE as a result of chronic diarrhea...
November 14, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27840366/dynamic-changes-in-helicobacter-pylori-status-following-gastric-cancer-surgery
#15
Kichul Yoon, Nayoung Kim, Jaeyeon Kim, Jung Won Lee, Hye Seung Lee, Jong-Chan Lee, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Sang-Hoon Ahn, Do Joong Park, Hyung Ho Kim, Yoon Jin Lee, Kyoung-Ho Lee, Young-Hoon Kim, Dong Ho Lee
Background/Aims: Helicobacter pylori eradication is recommended in patients with early gastric cancer. However, the possibility of spontaneous regression raises a question for clinicians about the need for "retesting" postoperative H. pylori status. Methods: Patients who underwent curative gastrectomy at Seoul National University Bundang Hospital and had a positive H. pylori status without eradication therapy at the time of gastric cancer diagnosis were prospectively enrolled in this study...
November 14, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27840365/gastroesophageal-reflux-in-neurologically-impaired-children-what-are-the-risk-factors
#16
Seung Kim, Hong Koh, Joon Soo Lee
Background/Aims: Neurologically impaired patients frequently suffer from gastrointestinal tract problems, such as gastroesophageal reflux disease (GERD). In this study, we aimed to define the risk factors for GERD in neurologically impaired children. Methods: From May 2006 to March 2014, 101 neurologically impaired children who received 24-hour esophageal pH monitoring at Severance Children's Hospital were enrolled in the study. The esophageal pH finding and the clinical characteristics of the patients were analyzed...
November 14, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27840363/therapy-with-direct-acting-antiviral-agents-for-hepatitis-c-related-liver-cirrhosis
#17
REVIEW
Nobuyuki Toshikuni
Chronic hepatitis C virus (HCV) infection may eventually lead to liver cirrhosis (LC), a condition associated with a high risk of liver failure and hepatocellular carcinoma. Although interferon (IFN)-based therapy has made substantial contributions to the management of HCV-infected patients, this therapy has limitations for LC patients in terms of eligibility, tolerability, relatively low and high rates of sustained virological response (SVR), and serious adverse events. Therapy with newly developed direct-acting antiviral agents (DAAs) can overcome these limitations in IFN-based therapy...
November 14, 2016: Gut and Liver
https://www.readbyqxmd.com/read/28053299/the-potential-role-of-elk-3-egr-1-signaling-pathway-in-the-epithelial-mesenchymal-transition-during-liver-fibrosis
#18
EDITORIAL
In Hee Kim
No abstract text is available yet for this article.
January 15, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28053298/another-face-of-contrast-enhanced-ultrasonography-a-diagnostic-tool-for-cirrhosis
#19
EDITORIAL
Soung Won Jeong
No abstract text is available yet for this article.
January 15, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28053297/role-of-smoking-as-a-risk-factor-in-east-asian-patients-with-crohn-s-disease
#20
EDITORIAL
Sung Chul Park, Yoon Tae Jeen
No abstract text is available yet for this article.
January 15, 2017: Gut and Liver
journal
journal
41747
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"