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Clinical Respiratory Journal

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https://www.readbyqxmd.com/read/29330970/gamma-glutamyl-transferase-activity-as-a-predictive-marker-for-severity-of-obstructive-sleep-apnea-syndrome-and-concomitant-hypertension
#1
Bozkus Fulsen
BACKGROUND: Chronic intermittent hypoxia, inflammation and oxidative stress are involved in resultant obstructive sleep apnea syndrome (OSAS), which may affect numerous regulatory mechanisms that play a role in the regulation of blood pressure. Gamma glutamyl transferase (GGT) is a novel marker in the prediction of cardiovascular risk. OBJECTIVE: The objective of this study was to investigate the correlation of serum levels of GGT with hypertension and the degree of the upper airway obstruction in subjects with OSAS...
January 13, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29330966/static-hyperinflation-is-associated-with-ventilatory-limitation-and-exercise-tolerance-in-adult-cystic-fibrosis
#2
Daniel Stevens
INTRODUCTION: Lung hyperinflation is a potential mechanism limiting exercise tolerance. However, available data on the impact of static hyperinflation on exercise performance in adult cystic fibrosis is lacking. Furthermore, the relative contribution of both static and dynamic hyperinflation to exercise performance is unknown. OBJECTIVES: To determine the impact of static hyperinflation on exercise tolerance and lung dynamics in adult cystic fibrosis. METHODS: Clinical data of 107 adult patients with cystic fibrosis, including pulmonary function, lung volumes, and cardiopulmonary exercise from the Toronto Cystic Fibrosis database were collected and analyzed...
January 13, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29330908/defining-expanded-areas-in-ebus-sampling-ebus-guided-trans-and-intra-pulmonary-artery-needle-aspiration-with-review-of-transvascular-ebus
#3
Ravindra M Mehta, Pavankumar R Biraris, Vallandramam Pattabhiraman, Arjun Srinivasan, Abhinav Singla, Sunil Kumar, Michael Cutaia
BACKGROUND: Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) has revolutionized the diagnostic approach to mediastinal diseases. Lesions located lateral to the pulmonary artery (trans-PA, Station 5), or in the lumen of the PA (intra-PA) are in the 'blind-spot' of EBUS. OBJECTIVES: We describe a case series where EBUS guided trans-pulmonary or intra-pulmonary aspiration (EBUS-TIPNA) was used for diagnosis. METHODS: Retrospective analysis of 10 patients who had EBUS-TIPNA over 3 years in 2 centers...
January 13, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29316316/serum-but-not-exhaled-breath-condensate-periostin-level-is-increased-in-competitive-athletes
#4
Marcin Kurowski, Janusz Jurczyk, Marzanna Jarzębska, Aleksandra Wardzyńska, Hubert Krysztofiak, Marek L Kowalski
INTRODUCTION: Periostin is a matricellular protein expressed by many tissues. Its release may be enhanced, among others, through mechanical stimulation of muscles and bones as well as by cytokines of allergic inflammation. OBJECTIVES: Our aim was to assess periostin levels in serum and exhaled breath condensate (EBC) of professional athletes, asthmatics and healthy controls. We also sought to determine whether acute treadmill exercise influences serum and EBC periostin...
January 8, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29316311/prevalence-of-influenza-a-infection-in-the-middle-east-a-systematic-review-and-meta-analysis
#5
REVIEW
Mohsen Moghoofei, Seyed Hamidreza Monavari, Shayan Mostafaei, Shima Hadifar, Amir Ghasemi, Farhad Babaei, Hoda Kavosi, Ahmad Tavakoli, Davod Javanmard, Maryam Esghaei, Nilofar Khodabandehlou
OBJECTIVE: This systematic review and meta-analysis was performed to determine the prevalence rate of influenza virus from different parts of Middle East region, and present an overall relative frequency (RF) for this region. METHODS: The authors performed a systematic literature review from several reliable databases such as PubMed, ISI Web of Science and Scopus during 2000-2016. Furthermore, the keywords of this research were "Influenza", "Subtype", "Seroprevalence", "Incidence", "Seroepidemiology", "H1N1", "H3N2", "H5N1", "H9N2", "Middle-East", and "Meta-analysis"...
January 8, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29316286/validation-of-the-dyspnoea-12-scale-into-portuguese-speaking-copd-patients
#6
Aline Aparecida Simsic, Janelle Yorke, Eloisa Gatti Regueiro, Valeria Pires Di Lorenzo, José Baddini-Martinez
BACKGROUND AND AIMS: Dyspnoea-12 assesses dyspnea based on the physical and affective components of the symptom. The aim of this study was to translate the Dyspnoea-12 into Portuguese, and to obtain validation data regarding the use of this tool in patients with chronic obstructive lung disease (COPD). METHODS: The English version of the scale Dyspnoea-12 underwent a formal translation process into Portuguese as spoken in Brazil with the final version being called Dyspnoea-12-Pt...
January 8, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29316277/modification-of-oxygen-concentrators-based-on-questionnaire-survey
#7
Masahiro Shinoda, Masaharu Shinkai, Akimichi Nagashima, Kenjiro Nagai, Kei Takagi, Takeshi Kaneko
BACKGROUND: In this study, we conducted a questionnaire survey to clarify and improve problems related to oxygen concentrators. METHODS: Using a questionnaire survey of 30 patients receiving long-term oxygen therapy for chronic respiratory failure, we investigated the necessity of using a remote controller, portability, fire prevention system, built-in battery type and so on. Patients were divided into two groups according to age, sex, underlying conditions, and amount of oxygen prescribed, then analyzed accordingly...
January 8, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29316273/pilot-project-physiologic-responses-to-a-high-intensity-active-video-game-with-copd-patients-tools-for-home-rehabilitation
#8
Andrée-Anne Parent, Vincent Gosselin-Boucher, Marilyn Houle-Peloquin, Claude Poirier, Alain-Steve Comtois
INTRODUCTION: Chronic Obstructive Pulmonary Disease (COPD) is a respiratory condition that causes a significant deterioration of the quality of life. However, exercise can improve the quality of life for COPD patients and it is for this reason previous study observed the effects of active video games to increase exercise. Using motion capture devices with short bursts of exercise never been tried with COPD patients. OBJECTIVES: The objective was to observe the feasibility of using this device safely and easily with COPD patients...
January 8, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29247592/relationship-between-smoking-and-and-total-antioxidant-status-total-oxidant-status-oxidative-stress-index-vit-c-vit-e
#9
M Merve Karademirci, Ruhusen Kutlu, Ibrahim Kilinc
BACKGROUND: Tobacco smoke contains many toxic, carcinogenic and mutagenic chemicals, as well as stable and unstable free radicals. In this study, we aimed to assess the vitamin E, vitamin C and total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI) in smoking and non-smoking men. METHODS: This case control analytical study was conducted on 78 smoking and 82 non-smoking men. Fagerström nicotine dependence test was used in order to assess the participants'addiction status...
December 16, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29243879/the-effects-of-smoking-on-vascular-endothelial-growth-factor-and-inflammation-markers-a-case-control-study
#10
Merve Guzeldulger Ugur, Ruhusen Kutlu, Ibrahim Kilinc
BACKGROUND AND AIMS: Chronic Obstructive Pulmonary Disease(COPD) is a type of obstructive lung disease characterized by long-term poor airflow. Tobacco smoking is the most common cause of COPD. In this study, we aimed to assess thevasculerendothelial growth factor (VEGF) and inflammation markers on smokers and non-smoking individuals. METHODS: Our study was a case-control study and 175 individuals who want to give up smoking constituted the case group. As a control group, 175 individuals who never smoked...
December 15, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29227046/prevalence-of-comorbidities-in-patients-with-obstructive-sleep-apnoea-syndrome-overlap-syndrome-obesity-hypoventilation-syndrome
#11
Donato Lacedonia, Giovanna Elisiana Carpagnano, Giulia Patricelli, Mauro Carone, Crescenzio Gallo, Incoronata Caccavo, Roberto Sabato, Annarita Depalo, Maria Aliani, Alberto Capozzolo, Maria Pia Foschino Barbaro
INTRODUCTION: Sleep-disordered breathing causes a burden to the sufferer, the healthcare system, and the society. Most studies have focused on Obstructive Sleep Apnea (OSA), however, the prevalence of comorbidities in patients affected by Overlap Syndrome (OS) and Obesity Hypoventilation Syndrome (OHS) has not been carefully evaluated. STUDY OBJECTIVES: The principal aim of this study was to identify the presence of comorbidities in patients suffering from OSA, OS, OHS and the differences in three groups of patients...
December 11, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29227032/efficacy-and-safety-of-low-dose-urokinase-for-the-treatment-of-hemodynamically-stable-aecopd-patients-with-acute-pulmonary-thromboembolism
#12
Xiaogang Jing, Guojun Zhang, Beifeng Zhang, Lingling Dai, Xi Wang, Liuqun Jia, Huan Wang, Lin An, Yuanjian Yang, Zhe Cheng
PURPOSE: The aim of this study was to assess the incidence of pulmonary thromboembolism (PTE) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD),and to evaluate the efficacy and safety of low-dose urokinase (UK) thrombolysis therapy when treating hemodynamically stable AECOPD patients with acute PTE (AECOPD-PTE). METHODS: A total of 419 AECOPD patients, including 96 AECOPD-PTE, were enrolled. A total of 30 AECOPD-PTE patients were collected retrospectively, and 66 AECOPD-PTE patients were prospectively divided into anticoagulation-only, low-dose UK and standard-dose UK groups...
December 11, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29227026/the-prevalence-of-asthma-in-iranian-adults-the-first-national-survey-and-the-most-recent-updates
#13
Mohammad Reza Fazlollahi, Mehdi Najmi, Mojtaba Fallahnezhad, Nastaran Sabetkish, Anoshirvan Kazemnejad, Katayoon Bidad, Raheleh Shokouhi Shoormasti, Maryam Mahloujirad, Zahra Pourpak, Mostafa Moin
BACKGROUND: The worldwide increase in the prevalence of asthma has made it a major public-health concern. We aimed to identify the prevalence of asthma and asthma symptoms in adults living in urban and rural areas of Iran as a populated country with about 80 millions of residents. METHODS: This cross-sectional study was conducted to estimate the prevalence of asthma in adults between 20 and 44 years old in all provinces of Iran. Data were collected by personal interview via a standardized questionnaire [European Community Respiratory Health Survey (ECRHS)] between November 2015 and February 2016...
December 11, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29227024/blood-biomarkers-as-predictors-of-long-term-mortality-in-copd
#14
Angelico Mendy, Erick Forno, Theophile Niyonsenga, Janvier Gasana
BACKGROUND: Blood biomarkers are easily accessible and might reflect chronic obstructive pulmonary disease (COPD) activity. AIM: The aim of this study was to determine whether a panel of blood biomarkers [C-reactive protein (CRP), neutrophils, eosinophils, albumin and vitamin D] could predict mortality in COPD. METHODS: We analyzed data from 431 COPD participants to the 2007-2010 National Health and Nutrition Examination Surveys who were followed for a median time of 36 months...
December 11, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29227023/sex-linked-difference-in-blood-oxygen-saturation
#15
Sagi Levental, Elie Picard, Francis Mimouni, Leon Joseph, Tal Y Samuel, Reuben Bromiker, Dror Mandel, Nissim Arish, Shmuel Goldberg
BACKGROUND: It is not known whether SpO2 in healthy volunteers is affected by sex. OBJECTIVE: to evaluate whether there are differences in SpO2 between young healthy adult males and females and to evaluate whether the differences are already present at birth. METHODS: We studied 2 cohorts of patients. The first one consisted of young adult volunteers (105 males and 102 females). In these patients, SpO2 was measured as well as selected anthropometric variables (height, weight), vital signs (respiratory rate, pulse rate and body temperature), and obtained data on menstrual cycle phase of the female participants...
December 11, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29215188/polymerase-chain-reaction-test-in-induced-sputum-of-patients-with-pulmonary-tuberculosis
#16
Verônica da Silva Paiva, Fernanda Luiza Staub, Dirceu Felipe Valentini, Regina Bones Barcellos, Karen Barros Schmid, Elis Regina Dalla Costa, Maria Lucia Rosa Rossetti, Paulo de Tarso Roth Dalcin, Denise Rossato Silva
INTRODUCTION: Induced sputum (IS) is an alternative method of obtaining sputum, but IS smears are frequently negative. Culture is more time consuming in its results, and less useful to guide the diagnosis. Polymerase chain reaction (PCR) is the most common methodology for rapid diagnosis of tuberculosis (TB), and few studies evaluated its role in IS samples. OBJECTIVES: The objective of this study is to determine the diagnostic yield of PCR for TB compared with culture in IS samples...
December 7, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29193790/airway-inflammatory-phenotypes-making-sputum-cell-evaluation-more-accessible-for-clinical-use
#17
LETTER
Patrizia Pignatti, Dina Visca, Veronica Leoni, Elisabetta Zampogna, Francesca Cherubino, Giovanni Sotgiu, Etienne Lucini, Antonio Spanevello
No abstract text is available yet for this article.
November 28, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29193785/contribution-of-hiatal-hernia-to-asthma-in-patients-with-gastroesophageal-reflux-disease
#18
Zhi-Tong Li, Feng Ji, Xin-Wei Han, Lin-Xia Gu, Li Wang, Yong-Qiang Yue, Zhong-Gao Wang
BACKGROUND: To determine the correlation between asthma and hiatal hernia (HH) in patients with gastroesophageal reflux disease (GERD)-related asthma requiring laparoscopic anti-reflux surgery. METHODS: One hundred and thirty-six GERD patients with medically refractory asthma with (80 patients) or without HH (56 patients) were enrolled. Gastroesophageal reflux disease was assessed by endoscopy, esophageal manometry, reflux monitoring and symptom questionnaires, and treated with laparoscopic Nissen fundoplication (LNF) or LNF with concomitant hiatal hernia repair (LNF-HHR)...
November 28, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29193717/is-venous-blood-gas-performed-in-the-emergency-department-predictive-of-outcome-during-acute-on-chronic-hypercarbic-respiratory-failure
#19
Lisa Domaradzki, Sahithi Gosala, Khaled Iskandarani, Andry Van de Louw
BACKGROUND: during acute on chronic hypercarbic respiratory failure (AHRF), arterial pH is associated with non-invasive ventilation (NIV) failure and mortality. Venous blood gas (VBG) has been proposed as a substitute for arterial blood gas, based on a good agreement between venous and arterial values. We assessed the predictive value of admission VBG on intubation rate, NIV failure and mortality during AHRF. METHODS: retrospective chart review of inpatients admitted between 2009 and 2015 with AHRF who had VBG performed on admission...
November 28, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29148205/inhaled-corticosteroids-and-the-risks-of-low-energy-fractures-in-patients-with-chronic-airway-diseases-a-propensity-score-matched-study
#20
Chun-Hao Tsai, Lin-Yu Laio, Cheng-Li Lin, Wei-Sheng Chung
BACKGROUND AND AIMS: Inhaled corticosteroids (ICSs) are crucial anti-inflammatory medications for chronic airway diseases. Studies investigating the relationship between ICSs and fractures in Asian populations are scant. We investigated whether ICSs increased the risk of low-energy fractures in patients with chronic airway diseases. METHODS: We used the Longitudinal Health Insurance Database to select patients aged 20 years and older with chronic airway diseases (asthma and COPD) between 2000 and 2011 as the base cohort...
November 17, 2017: Clinical Respiratory Journal
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