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Clinical Respiratory Journal

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https://www.readbyqxmd.com/read/28925009/efficacy-of-patients-preferred-exercise-modalities-in-chronic-obstructive-pulmonary-disease-a-parallel-group-randomized-clinical-trial
#1
Meng Wu, Lu-Qian Zhou, Shi Li, Su Zhao, Hui-Jun Fan, Jie-Min Sun, Xiao-Nan Li, Jian Luo, An-Qi Wang, Jian-Ping Wu, Xiaoying Li, Jin-Nong Zhang
INTRODUCTION: Physical exercise effectively improves health-related quality of life in patients with chronic obstructive pulmonary disease (COPD). However, application of this medical intervention is problematic, due to poor adherence to the exercise program or unawareness of the significance of this intervention. OBJECTIVE: To determine whether COPD patients who adopted personal-preferred exercise modalities (PPEMs) for daily training would demonstrate sustained benefits due to improved adherence...
September 19, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28905517/the-prognostic-significance-of-tricuspid-valve-regurgitation-in-pulmonary-arterial-hypertension
#2
Libo Chen, Carolyn M Larsen, Rachel J Le, Heidi M Connolly, Sorin V Pislaru, Joseph G Murphy, Michael D McGoon, Robert P Frantz, Garvan C Kane
INTRODUCTION: Tricuspid valve regurgitation (TR) is a frequent finding in patients with pulmonary arterial hypertension (PAH). However, its prognostic significance and relation to PAH, while suspected, are poorly understood. We assessed 727 consecutive patients with newly diagnosed PAH who underwent transthoracic echocardiographic evaluation of tricuspid valve function. OBJECTIVES: The study objective was to determine the association of TR presence and severity with patient characteristics, pulmonary artery hemodynamics, and outcome...
September 14, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28905483/lung-cancer-in-young-women-in-southern-sweden-a-descriptive-study
#3
Ildikó Fritz, Håkan Olsson
INTRODUCTION: Lung cancer, a common malignancy and cause of cancer-related deaths, is strongly linked to several environmental exposures, and thus primarily affects the elderly. Formerly a man's disease, its incidence is rising among women, and lung cancer is now more common in women than men in Sweden. Women are particularly over-represented among young patients. While overall cancer mortality in Europe is decreasing, female lung cancer mortality is increasing. OBJECTIVES: We describe the epidemiological presentation of lung cancer in young Swedish women, aiming to pinpoint its risk factors for young women...
September 14, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28884501/procalcitonin-erythrocyte-sedimentation-rate-and-c-reactive-protein-in-acute-pulmonary-exacerbations-of-cystic-fibrosis
#4
Geoffrey Loh, Ilya V Ryaboy, Alicia French, Andrew Skabelund
INTRODUCTION: Acute pulmonary exacerbations of cystic fibrosis (APECF) are a leading cause of morbidity and mortality among patients with CF. APECF require frequent administration of antibiotics and subsequently lead to development of resistant organisms. OBJECTIVES: Identify inflammatory markers that may be help identify need for antibiotics and exacerbation as well as predict risk of exacerbations. METHODS: 17 patients were enrolled and baseline ESR, CRP, and procalcitonin levels were obtained in addition to obtaining these levels during admissions for Acute Pulmonary Exacerbations of Cystic Fibrosis (APECF)...
September 7, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28876537/steroid-phobia-chinese-medicine-and-asthma-control
#5
Ka Ian Ip, Kam Lun Hon, Yin Ching Kathy Tsang, Ngan Ho Theresa Leung
BACKGROUND: Inhaled corticosteroids (ICS) are the mainstay of treatment for asthma. Corticosteroid (CS) phobia and fears are prevalent and these may influence therapeutic efficacy and asthma control. AIM: To evaluate if CS fear is associated with asthma control in children Methods: Patients aged > 4 years old with asthma at a pediatric outpatient clinic were surveyed, and the Asthma Control Test (ACT) was used for assessment of asthma control. RESULTS: Ninety-eight patients and their parents were interviewed...
September 6, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28876508/the-effects-of-pirfenidone-in-patients-with-an-acute-exacerbation-of-interstitial-pneumonia
#6
Takuma Matsumura, Kenji Tsushima, Mitsuhiro Abe, Kenichi Suzuki, Kazutaka Yamagishi, Akane Matsumura, Yasunori Ichimura, Jun Ikari, Jiro Terada, Koichiro Tatsumi
Introdcution: The prognosis of patients with an acute exacerbation of interstitial pneumonia (AE-IP) is poor. Pirfenidone (PFD) reduces the disease progression in idiopathic pulmonary fibrosis. OBJECTIVES: The purpose of this study was evaluating whether the administration of PFD improved the outcomes of AE-IP. METHODS: We conducted a retrospective study of 31 patients with AE-IP who did not recover between 7 and 14 days after an initial treatment. Fourteen patients received PFD within 2 weeks (PFD group) of the AE, while 17 patients were treated without PFD (Non-PFD group)...
September 6, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28862397/empire-registry-czech-part-impact-of-demographics-pulmonary-function-and-hrct-on-survival-and-clinical-course-in-idiopathic-pulmonary-fibrosis
#7
Martina Doubková, Jan Švancara, Michal Svoboda, Martina Šterclová, Vladimír Bartoš, Martina Plačková, Ladislav Lacina, Monika Žurková, Ilona Binková, Radka Bittenglová, Vladimíra Lošťáková, Zdeněk Merta, Lenka Šišková, Richard Tyl, Pavlína Lisá, Hana Šuldová, František Petřík, Jana Pšikalová, Vladimír Řihák, Tomáš Snížek, Pavel Reiterer, Jiří Homolka, Pavlína Musilová, Jaroslav Lněnička, Peter Palúch, Roman Hrdina, Renata Králová, Hana Hortvíková, Jana Strenková, Martina Vašáková
INTRODUCTION: Prognostic factors of idiopathic pulmonary fibrosis (IPF) currently recognized include changes in vital capacity and radiologic findings. However, most of the prognostic studies in IPF are based on clinical studies with preselected IPF populations. Therefore, we decided to analyze the factors influencing IPF prognosis based on the real-practice data from our IPF registry. METHODS: Data of 514 subjects consecutively entered since 2012 into Czech EMPIRE IPF registry were analyzed...
September 1, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28862396/association-between-lung-function-physical-activity-level-and-postural-evaluation-variables-in-adult-patients-with-cystic-fibrosis
#8
Inaê Angélica Cherobin, Paulo de Tarso Roth Dalcin, Bruna Ziegler
INTRODUCTION: With the evolution of the cystic fibrosis (CF) disease, the decline of lung function associated with metabolic disorders and malnutrition, causes alterations in respiratory mechanics, musculoskeletal disorders and thoracic deformities, bringing injury to the individual's quality of life. OBJECTIVE: To verify the association between lung function, physical activity level and postural evaluation variables in adults with CF. METHODS: All patients underwent clinical evaluation and spirometry...
September 1, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28862394/efficacy-and-safety-of-a-calcium-sensitizer-levosimendan-in-patients-with-right-heart-failure-due-to-pulmonary-hypertension
#9
Rong Jiang, Qin-Hua Zhao, Wen-Hui Wu, Rui Zhang, Ping Yuan, Su-Gang Gong, Jing He, Ci-Jun Luo, Hong-Ling Qiu, Lan Wang, Jin-Ming Liu
BACKGROUND: Despite using vasoactive and PH specific therapies, the in-hospital mortality of severe pulmonary hypertension (PH) with right heart failure (RHF) is high. We conducted a prospective analysis evaluating the efficacy and safety of levosimendan in PH patients with severe acute RHF. METHODS: Forty-five PH patients hospitalized between Jan 2016 to Nov 2016 were recruited into a single arm, prospective, open-label study. Levosimendan was administered at the rate of 0...
September 1, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28862387/symptom-evaluation-during-the-methacholine-test-does-it-add-to-the-interpretation-of-the-test-results-based-on-the-pc20fev1
#10
Abraham B Bohadana, Pascal Wild, Gabriel Izbicki
PURPOSE: Conventionally, symptoms occurring during the methacholine test are not taken into account when interpreting the test results. We examined whether the evaluation of methacholine-induced symptoms (MIS) added to the test interpretation based on the PC20FEV1 by assessing their prevalence, their similarity with symptoms justifying referral and their relationship with airway responsiveness. METHODS: Eighty-two patients with suspected asthma completed a questionnaire of symptoms and underwent bronchial challenge with methacholine...
September 1, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28862383/serum-aspergillus-fumigatus-specific-igg-antibody-decreases-after-antifungal-treatment-in-chronic-pulmonary-aspergillosis-patients
#11
LETTER
Yake Yao, Hua Zhou, Qing Yang, Guohua Lu, Yunsong Yu, Yihong Shen, Jianying Zhou
No abstract text is available yet for this article.
September 1, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28846200/efficiency-of-the-lung-flute-for-sputum-induction-in-patients-with-presumed-pulmonary-tuberculosis
#12
Kentaro Sakashita, Akira Fujita, Mikio Takamori, Takayuki Nagai, Tomoshige Matsumoto, Takefumi Saito, Taku Nakagawa, Kenji Ogawa, Eriko Shigeto, Yasuto Nakatsumi, Hajime Goto, Satoshi Mitarai
INTRODUCTION: High quality sputum helps increase the sensitivity of the diagnosis of pulmonary tuberculosis. OBJECTIVES: To evaluate the efficiency of the acoustic device (Lung Flute; LF) in sputum induction compared with the conventional method, hypertonic saline inhalation (HSI). METHODS: In this crossover study, patients with presumed pulmonary tuberculosis submitted three consecutive sputa: the first sputum without induction and the second and third ones using LF and HSI...
August 28, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28842971/the-impact-of-pediatric-obesity-on-hospitalized-children-with-lower-respiratory-tract-infections-in-the-united-states
#13
Yusuke Okubo, Kotaro Nochioka, Marcia A Testa
OBJECTIVE: Obesity is the most common public health problem and is a clinically complicating risk factor among hospitalized children. The impact of pediatric obesity on the severity and morbidity of lower respiratory tract infections remains unclear. MATERIALS AND METHODS: We conducted a retrospective cohort study of bronchitis and pneumonia among children aged 2-20 years using hospital discharge records. The data were obtained from the Kid's Inpatient Database in 2003, 2006, 2009, and 2012, and were weighted to estimate the number of hospitalizations in the United States...
August 26, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28842969/pleuroparenchymal-fibroelastosis-in-heterogeneous-clinical-conditions-clinicopathologic-analysis-of-7-cases
#14
Yoon Jin Cha, Joungho Han, Man Pyo Chung, Tae Jung Kim, Sumin Shin
BACKGROUND AND AIMS: Pleuroparenchymal fibroelastosis (PPFE) is classified as a rare idiopathic interstitial pneumonia, and its clinicopathologic features remain unclear. We sought to investigate the clinical, radiologic, and pathologic features of patients with histologically proven PPFE. METHODS: Seven patients who had histologic features of PPFE that were definitive or consistent with PPFE were included. Clinical data and radiologic findings of chest computed tomography were obtained...
August 26, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28842946/anxiety-and-depression-in-adult-outpatients-with-bronchiectasis-associations-with-disease-severity-and-health-related-quality-of-life
#15
Yong-Hua Gao, Wei-Jie Guan, Ya-Nan Zhu, Rong-Chang Chen, Guo-Jun Zhang
BACKGROUND: Anxiety and depression might frequently affect bronchiectasis patients, but data in Chinese patients, including their association with disease severity assessed with Bronchiectasis Severity Index (BSI) and FACED score, are limited. OBJECTIVE: To investigate the rate, risk factors, association with disease severity and impact of anxiety and depression on health-related quality of life (HRQoL) in adult outpatients with steady-state bronchiectasis. METHODS: This cross-sectional study included 163 outpatients (102 females; mean age, 45...
August 26, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28834599/the-value-of-macrophage-inhibitory-cytokine-1-level-in-differentiating-benign-from-malignant-solitary-pulmonary-nodules
#16
Chun Hua Xu, Jin Shan Xue, Xiu Wei Zhang, Li Ke Yu, Yong Lin
INTRODUCTION: Macrophage inhibitory cytokine-1 (MIC-1), a transforming growth factor-β superfamily cytokine, is involved in tumor pathogenesis, and its measurement can be used as a clinical tool for the diagnosis of a wide range of cancers. OBJECTIVES: The aim of this study was to explore the diagnostic value of serum MIC-1 in patients with solitary pulmonary nodules (SPNs). METHODS: Serum specimens from 158 malignant SPN patients, 110 benign SPN patients, along with 120 healthy volunteers...
August 23, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28779548/how-is-chronic-non-communicable-respiratory-conditions-research-reported-in-european-newspapers-an-impact-assessment-for-policy
#17
Elena Pallari, Grant Lewison, Richard Sullivan
BACKGROUND: Newspapers are an important means for the communication of medical research findings to policy-makers and the public, but may distort their views on the relative importance of research into, and burden from, different respiratory diseases. METHODS: A systematic search strategy based on respiratory-related keywords was developed and translated into 15 European languages to identify relevant stories in 26 newspapers from eight countries in 2002-2013. Details of the stories were recorded on Excel and coded based on the reported respiratory conditions (asthma, chronic obstructive pulmonary disease (COPD) and other) and research types...
August 5, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28779547/endothelial-dysfunction-assessment-by-noninvasive-peripheral-arterial-tonometry-in-patients-with-chronic-obstructive-pulmonary-disease-compared-with-healthy-subjects
#18
Mario Malerba, Alessandro Radaeli, Matteo Nardin, Enrico Clini, Giovanna Elisiana Carpagnano, Edoardo Sciatti, Francesca Salghetti, Ivano Bonadei, Fabio Platto, Enrico Vizzardi
INTRODUCTION: Patients with chronic obstructive pulmonary disease (COPD) have an increased risk of cardiovascular disease. The endothelial dysfunction likely plays a central role in increasing cardiovascular risk. OBJECTIVES: This cross-sectional, study investigated the prevalence and extent of endothelial dysfunction in patients with stable COPD. METHODS: Peripheral arterial tonometry (PAT) was measured by post-ischemic reactive hyperemia index (RHI) in 16 COPD patients, 16 healthy controls and 16 subjects with treated systemic arterial hypertension (AH) and analysed with covariates condition (dyslipidemia, and medications)...
August 5, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28779544/a-randomized-double-blind-controlled-trial-comparing-3-sedation-regimens-during-flexible-bronchoscopy-dexmedetomidine-alfentanil-and-lidocaine
#19
Moussa Riachy, Georges Khayat, Ihab Ibrahim, Zeina Aoun, Georges Dabar, Taha Bazarbachi, Nadine Khalil, Bassem Habr
INTRODUCTION: No standardized sedation protocol is available for flexible bronchoscopy. OBJECTIVES: To evaluate the efficacy and safety of three regimens used for sedation during flexible bronchoscopy. METHODS: This randomized double-blind controlled trial assessed patients undergoing bronchoscopy and receiving lidocaine alone (C) or combined with dexmedetomidine (D) or alfentanil (A). Tolerance was assessed using the bronchoscopy score, and level of sedation was assessed using the Nursing Instrument for the Communication of Sedation...
August 5, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28776954/effectiveness-of-pulmonary-rehabilitation-in-copd-patients-receiving-long-term-oxygen-therapy
#20
Hulya Sahin, Yelda Varol, Ilknur Naz, Fevziye Tuksavul
AIM: It has been demonstrated that long-term oxygen therapy increased exercise capacity, improved the quality of life, reduced hospitalization, and increased life expectancy in chronic hypoxemic COPD patients. The present study aims to evaluate the effectiveness of pulmonary rehabilitation (PR) in COPD patients receiving long-term oxygen therapy (LTOT) compared to COPD patients not receiving LTOT. MATERIAL AND METHOD: Chronic hypoxemic COPD patients using LTOT (LTOT group) and COPD patients not receiving LTOT (non-LTOT group) who participated in this study underwent a comprehensive 8-week outpatient PR program...
August 4, 2017: Clinical Respiratory Journal
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