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Clinical Respiratory Journal

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https://www.readbyqxmd.com/read/30015400/hla-drb1-allele-frequency-and-immunological-response-in-obstructive-sleep-apnea-syndrome-in-turkish-population
#1
Muhammet Yusuf Tepebaşı, Nilüfer Şahin Calapoğlu, Önder Öztürk, Okan Sancer, Taner Gonca
INTRODUCTION: Obstructive sleep apnea syndrome (OSAS) is a complex, polygenic and multifactorial disease. The relationship between Human Leukocyte Antigen (HLA) polymorphisms and sleep disturbances has been established, but the relationship with HLA alleles has not been fully clarified. In addition, sleep deprivation in OSAS patients can cause changes that affect the components and responses of the immune system. OBJECTIVE: The aim of this study has assessed the effect of HLA-DRB1 alleles on OSAS disease and the changes occurring in immune response cells in Turkish population...
July 17, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/30015394/the-serum-kl-6-levels-in-untreated-idiopathic-pulmonary-fibrosis-can-naturally-decline-in-association-with-disease-progression
#2
Hiroshi Ishii, Hisako Kushima, Yoshiaki Kinoshita, Masaki Fujita, Kentaro Watanabe
BACKGROUND: Serum KL-6 is known to be a useful biomarker for the diagnosis and assessment of the disease activity in idiopathic pulmonary fibrosis (IPF). However, some patients with untreated IPF present with a serial decline in their serum KL-6 levels, despite showing clinical progression. OBJECTIVES: The aim of the present study was to evaluate the association between the time course of the serum KL-6 levels and the clinical course of patients with untreated IPF...
July 17, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/30015374/malignancy-in-the-tracheal-bronchus-a-case-series-and-review-of-the-literature
#3
Elina Levin, Mark Bowling
BACKGROUND/AIMS: The tracheal bronchus is a rare congenital abnormality with incidence reported in a range of 0.1% to 2%. Infrequently, malignancy has been reported as occurring in the tracheal bronchus. In order to ascertain a relationship between malignancy and the tracheal bronchus, we performed a literature review and present a case series. METHODS: We reviewed 21 case reports of malignancy occurring in the tracheal bronchus. CONCLUSION: Although the number of cases is limited, it appears that bronchoscopy is the most frequently utilized diagnostic tool...
July 17, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/30015372/pre-intensive-care-unit-intubation-and-subsequent-delayed-intensive-care-unit-admission-is-independently-associated-with-increased-occurrence-of-ventilator-associated-pneumonia
#4
Eirini Tsakiridou, Anna-Maria Mega, Epameinondas Zakynthinos, Theodora Melissopoulou, George Stamos, Konstantinos Argyriou, Stamatoula Pangrati, Ioannis Deliolanis, Ioannis Floros
INTRODUCTION: Critically ill intubated patients are at risk for ventilator-associated pneumonia. However, intubation may not occur in intensive care unit (ICU) and subsequent ICU admission may be delayed. OBJECTIVES: To evaluate whether intubation >24 hours prior ICU admission and delay in ICU admission is associated with ventilator-associated pneumonia (VAP) in non-trauma critically ill patients. MATERIALS AND METHODS: Prospective observational study conducted in a medical-surgical ICU of a tertiary hospital...
July 17, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/30014567/high-flow-nasal-cannulae-versus-non-invasive-ventilation-in-moderate-hypercapnic-respiratory-failure-different-roads-same-destination-but-doubtful-equality
#5
LETTER
Guy W Soo Hoo, Antonio M Esquinas, Habib M R Karim
Nasal high flow oxygen (NHF) is a growing therapy in many forms of hypoxemic respiratory failure. The impact of NHF in chronic respiratory failure has been yet controversial. In this line we read the report from Lee and colleagues with interest,1 but there are several areas that warrant comment. This article is protected by copyright. All rights reserved.
July 16, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/30005142/recent-developments-in-the-management-of-pleural-infection-a-comprehensive-review
#6
Eihab O Bedawi, Maged Hassan, Najib M Rahman
OBJECTIVES: Pleural infection is a condition commonly encountered by the respiratory physician. This review aims to provide the reader with an update on the most recent data regarding the epidemiology, microbiology and the management of pleural infection. DATA SOURCE: Medline was searched for articles related to pleural infection using the terms 'pleural infection', 'empyema' and 'parapneumonic'. The search was limited to the years 1997-2017. Only human studies and reports in English were included...
July 13, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/30004629/what-is-the-significance-of-non-specific-pleuritis-a-trick-question
#7
Julius Janssen, Fabien Maldonado, Muzaffer Metintas
Non-specific pleuritis (NSP) is defined as fibrinous or inflammatory pleuritis which cannot be attributed to a specific benign or malignant etiology. It can be diagnosed in biopsies in up to 30% of cases of exudative pleuritis after thoracoscopy, with a mean of 19.2%. In 66 out of 469 (14.2%) patients in combined series, a malignant pleural disease (mostly mesothelioma) was found during a follow-up of at least 21 months. Most likely, a follow-up time of 12 months is sufficient, although the current routine is a follow-up of 2 years...
July 13, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/30004178/association-between-asthma-and-migraine-a-cross-sectional-study-of-over-110-000-adolescents
#8
Yael Graif, Tamy Shohat, Yossy Machluf, Rivka Farkash, Yoram Chaiter
BACKGROUND: Epidemiological studies have reported an association between asthma and migraine, mainly in adults. OBJECTIVE: To examine the association between specialist-diagnosed asthma and migraine among adolescents. METHODS: The electronic database of a recruitment center was retrospectively searched for all 17-year-old draftees during the years 1987-2010. Diagnoses of asthma and migraine were made by certified specialists. The prevalence of migraine was compared among draftees with and without asthma...
July 13, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29931773/association-between-hand-grip-strength-with-weaning-and-intensive-care-outcomes-in-copd-patients-a-pilot-study
#9
Aliae Ar Mohamed-Hussein, Hoda A Makhlouf, Zahraa I Selim, Waleed Gamaleldin Saleh
BACKGROUND: In COPD weight loss and muscle wasting contribute significantly to morbidity, disability and handicap. Dominant-handgrip strength for evaluation of muscle strength has not been tested as a parameter to predict outcome of weaning from mechanical ventilation (MV). OBJECTIVES: to evaluate the association between handgrip strength and the duration and success of weaning and extubation outcome. PATIENTS AND METHODS: This prospective study included 34 COPD patients requiring MV for at least 48 hours...
June 22, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29920961/is-an-fev-1-of-80-predicted-a-normal-spirometry-in-cystic-fibrosis-children-and-adults
#10
Peter König, Zarah Ner, James D Acton, Bin Ge, John Hewett
Introduction- FEV1 is considered the gold standard spirometric measure for the assessment and management of cystic fibrosis lung disease. Recent evidence suggests that tests at lower lung volumes may be more sensitive. Objectives- To assess how many other spirometric tests are abnormal in the presence of a normal FEV1 (≥80%) and which spirometric tests are most sensitive in detecting airway obstruction. Methods -This was a retrospective analysis of 3,169 spirometry tests on 184 patients with cystic fibrosis aged 6 - 57 years...
June 19, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29873202/prognostic-evaluation-of-serum-ferritin-in-acute-exacerbation-of-idiopathic-pulmonary-fibrosis
#11
Noriyuki Enomoto, Yoshiyuki Oyama, Yasunori Enomoto, Masashi Mikamo, Masato Karayama, Hironao Hozumi, Yuzo Suzuki, Masato Kono, Kazuki Furuhashi, Tomoyuki Fujisawa, Naoki Inui, Yutaro Nakamura, Takafumi Suda
BACKGROUND: Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) has an extremely poor prognosis. The role of ferritin in the pathogenesis of AE-IPF is not well known while serum ferritin is a key prognostic indicator for patients with clinically amyopathic dermatomyositis with rapidly progressive interstitial pneumonia. OBJECTIVE: To elucidate the clinical importance of serum ferritin in patients with AE-IPF. METHODS: Thirty-seven patients (48 episodes), who were diagnosed with AE-IPF and treated at our hospital between 1997 and 2015, were retrospectively studied...
June 5, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29873200/does-the-2017-revision-improve-the-ability-of-gold-to-predict-risk-of-future-moderate-and-severe-exacerbation
#12
Serhat Erol, Elif Sen, Yagmur Gizem Kilic, Ahmed Yousif, Oznur Akkoca Yildiz, Turan Acican, Sevgi Saryal
INTRODUCTION: In 2017 update, GOLD separated spirometry from ABCD classification. OBJECTIVES: The aim was to investigate the predictive reliability of GOLD 2017 grading system in terms of future moderate and severe exacerbations. METHODS: COPD patients were classified into A to D groups according to GOLD 2011 and 2017. Patients who were assigned to C/D groups according to GOLD 2011 were divided into subgroups C 1/D1, C2/D2, C3/D3 according to FEV1 % of predicted and exacerbation history...
June 5, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29873194/pulsus-paradoxus
#13
REVIEW
Malay Sarkar, Rajeev Bhardwaz, Irappa Madabhavi, Srinivas Gowda, Kushal Dogra
OBJECTIVES: Reviewed the etiologies, pathophysiologic mechanisms, detection and clinical significance of pulsus paradoxus in various conditions. DATA SOURCE: We searched PubMed, EMBASE, and the CINAHL from inception to June 2017. We used the following search terms: Pulsus paradoxus, pericardial effusion, acute asthma, ventricular interdependence and so forth. All types of study were chosen. RESULTS AND CONCLUSION: Legendary physician Sir William Osler truly said that "Medicine is learned by the bedside and not in the classroom...
June 5, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29873189/prevalence-and-features-of-asthma-copd-overlap-in-the-u-s-2007-2012
#14
Angelico Mendy, Erick Forno, Theophile Niyonsenga, Ryan Carnahan, Janvier Gasana
BACKGROUND: Perceived to be distinct, asthma and chronic obstructive pulmonary disease (COPD) can co-exist and potentially have a worse prognosis than the separate diseases. Yet, little is known about the exact prevalence and the characteristics of the Asthma-COPD overlap (ACO) in the U.S. POPULATION: <AbstractText Label="AIMS" NlmCategory="OBJECTIVE">To determine ACO prevalence in the U.S., identify ACO predictors, examine ACO association with asthma and COPD severity, and describe distinctive spirometry and laboratory features of ACO...
June 5, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29869447/the-prevalence-of-children-asthma-a-few-comments
#15
LETTER
Javad Ghaffari
No abstract text is available yet for this article.
June 5, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29790656/clinical-characteristics-and-validation-of-bronchiectasis-severity-score-systems-for-post-tuberculosis-bronchiectasis
#16
Hong Wang, Xiao-Bin Ji, Cheng-Wei Li, Hai-Wen Lu, Bei Mao, Shuo Liang, Ke-Bin Cheng, Jiu-Wu Bai, Miguel Angel Martinez-Garcia, Jin-Fu Xu
INTRODUCTION: Lung damage related to tuberculosis is a major contributor to the etiology of bronchiectasis in China. It is unknown whether bronchiectasis severity score systems are applicable in these cases. OBJECTIVES: To evaluate the clinical characteristics and validation of bronchiectasis severity score systems for post-tuberculosis bronchiectasis. METHODS: The study enrolled 596 bronchiectasis patients in Shanghai Pulmonary Hospital between January 2011 and December 2012...
May 23, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29729130/co2-retention-the-key-to-stopping-hiccups
#17
Toshiro Obuchi, Satoshi Shimamura, Naofumi Miyahara, Naoyuki Fujimura, Akinori Iwasaki
BACKGROUND: While investigating the mechanisms behind hiccups, our team discovered what could be the sufficient physiological conditions for terminating even persistent cases. METHODS: To investigate the role of CO2 retention, a healthy male volunteer was asked to perform 3 kinds of rebreathing experiments using different materials: (I) a 20L air-filled plastic bag, (II) a 20L air-filled plastic bag with a 1.5 × 1.5 cm hole, and (III) a 20L oxygen-filled plastic bag...
May 5, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29729122/watch-pat-versus-level-iii-device-in-diagnosing-sleep-disordered-breathing-in-first-myocardial-infarction
#18
Jeanette Ting, Li-Ling Tan, Iswaree Devi Balakrishnan, Siew-Pang Chan, Tiong-Cheng Yeo, Chi-Hang Lee
BACKGROUND: Watch-PAT 200, a novel portable sleep device worn on the wrist, has been validated against polysomnography. Although sleep disordered breathing (SDB) screening is recommended in patients with cardiovascular disease, no study has reported a comparison of results from Watch-PAT 200 and level III portable devices.  Methods: Patients (n=140) admitted with a first ST-segment elevation myocardial infarction (STEMI) participated in a hospital-based sleep study using the Watch-PAT 200 and a level III portable device (Embletta Gold) simultaneously within five days of admission...
May 5, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29729121/predictive-equations-for-respiratory-muscle-strength-by-anthropometric-variables
#19
Fernanda Figueiroa Sanchez, Cássio Daniel Araújo da Silva, Maria Clara de Souza Pereira Gama Maciel, Jamilly Rebouças Demósthenes Marques, Elisa Brosina de Leon, Roberta Lins Gonçalves
Recent studies have pointed out divergences in the predictive quality of reference equations for respiratory muscle strength, alerting the need to introduce into these equations specific variables for certain target populations. OBJECTIVES: Propose predictive equations of respiratory muscle strength by the variables Body Weight and Body Mass Index (BMI = weight / height²). MATERIAL AND METHODS: A cross-sectional study, the evaluation was made by the Test of Maximum Static Respiratory Pressures (MIP e MEP) according to standard protocol of the Brazilian Society of Pneumology and Tisiology...
May 5, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29679518/new-insights-in-the-use-of-pleural-ultrasonography-for-diagnosis-and-treatment-of-pleural-disease
#20
Giampietro Marchetti, Sabrina Arondi, Francesca Baglivo, Sara Lonni, Federico Quadri, Alberto Valsecchi, Nicola Venturoli, Paolo Ceruti
The use of transthoracic ultrasound has acquired a wide consensus among respiratory physicians during the last few years. The developing of portable and easily available devices favorites patient's bedside evaluation. Transthoracic ultrasound provides rapid, real-time and low-cost diagnostic information, allowing image-guided chest interventions and reducing procedural risks. The different acoustic impedance between aerated and not aerated organs produces artifacts known as A lines, B lines, sliding sign, lung point, etc...
April 21, 2018: Clinical Respiratory Journal
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