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Clinical Respiratory Journal

Toshiro Obuchi, Satoshi Shimamura, Naofumi Miyahara, Naoyuki Fujimura, Akinori Iwasaki
BACKGROUND: While investigating the mechanisms behind hiccups, our team discovered what could be the sufficient physiological conditions for terminating even persistent cases. METHODS: To investigate the role of CO2 retention, a healthy male volunteer was asked to perform 3 kinds of rebreathing experiments using different materials: (I) a 20L air-filled plastic bag, (II) a 20L air-filled plastic bag with a 1.5 × 1.5 cm hole, and (III) a 20L oxygen-filled plastic bag...
May 5, 2018: Clinical Respiratory Journal
Jeanette Ting, Li-Ling Tan, Iswaree Devi Balakrishnan, Siew-Pang Chan, Tiong-Cheng Yeo, Chi-Hang Lee
BACKGROUND: Watch-PAT 200, a novel portable sleep device worn on the wrist, has been validated against polysomnography. Although sleep disordered breathing (SDB) screening is recommended in patients with cardiovascular disease, no study has reported a comparison of results from Watch-PAT 200 and level III portable devices.  Methods: Patients (n=140) admitted with a first ST-segment elevation myocardial infarction (STEMI) participated in a hospital-based sleep study using the Watch-PAT 200 and a level III portable device (Embletta Gold) simultaneously within five days of admission...
May 5, 2018: Clinical Respiratory Journal
Fernanda Figueiroa Sanchez, Cássio Daniel Araújo da Silva, Maria Clara de Souza Pereira Gama Maciel, Jamilly Rebouças Demósthenes Marques, Elisa Brosina de Leon, Roberta Lins Gonçalves
Recent studies have pointed out divergences in the predictive quality of reference equations for respiratory muscle strength, alerting the need to introduce into these equations specific variables for certain target populations. OBJECTIVES: Propose predictive equations of respiratory muscle strength by the variables Body Weight and Body Mass Index (BMI = weight / height²). MATERIAL AND METHODS: A cross-sectional study, the evaluation was made by the Test of Maximum Static Respiratory Pressures (MIP e MEP) according to standard protocol of the Brazilian Society of Pneumology and Tisiology...
May 5, 2018: Clinical Respiratory Journal
Giampietro Marchetti, Sabrina Arondi, Francesca Baglivo, Sara Lonni, Federico Quadri, Alberto Valsecchi, Nicola Venturoli, Paolo Ceruti
The use of transthoracic ultrasound has acquired a wide consensus among respiratory physicians during the last few years. The developing of portable and easily available devices favorites patient's bedside evaluation. Transthoracic ultrasound provides rapid, real-time and low-cost diagnostic information, allowing image-guided chest interventions and reducing procedural risks. The different acoustic impedance between aerated and not aerated organs produces artifacts known as A lines, B lines, sliding sign, lung point, etc...
April 21, 2018: Clinical Respiratory Journal
Marc Beaumont, Patrice Forget, Francis Couturaud, Gregory Reychler
OBJECTIVES: In chronic obstructive pulmonary disease (COPD), quality of life and exercise capacity are altered in relationship to dyspnea. Benefits of inspiratory muscle training (IMT) on quality of life, dyspnea and exercise capacity were demonstrated, but when it is associated to pulmonary rehabilitation (PR), its efficacy on dyspnea is not demonstrated. The aim of this systematic review with meta analysis was to verify the effect of IMT using threshold devices in COPD patients on dyspnea, quality of life, exercise capacity and inspiratory muscles strength, and the added effect on dyspnea of IMT associated with PR (versus PR alone)...
April 17, 2018: Clinical Respiratory Journal
Derya Özden Omaygenç, Nermin Ünal, Saadet İpek Edipoğlu, Tuğçe Barca Şeker, Mehmet Akif Özgül, Demet Turan, Cengiz Özdemir, İbrahim Oğuz Karaca, Erdoğan Çetinkaya
OBJECTIVE: Regarding the fact that rigid bronchoscopy is generally performed under general anesthesia and this patient subgroup is remarkably morbid, encountering procedure and/or anesthesia related complications are highly likely. Here, we aimed to assess factors influencing recovery and detect possible determinants of adverse event occurence during these operations performed in a tertiary referral centre. METHODS: 81 consecutive ASA I-IV patients were recruited for this investigation...
April 16, 2018: Clinical Respiratory Journal
Jane A Shaw, Elvis M Irusen, Andreas H Diacon, Coenraad Fn Koegelenberg
Tuberculosis (TB) is the leading infectious cause of death worldwide, and the commonest cause of death in people living with HIV. Globally, pleural TB remains one of the most frequent causes of pleural exudates, particularly in TB-endemic areas and in the HIV positive population. Most TB pleural effusions are exudates with high adenosine deaminase (ADA), lymphocyte-rich, straw-coloured and free flowing, with a low yield on mycobacterial culture. TB pleurisy can also present as loculated neutrophil-predominant effusions which mimic parapneumonic effusions...
April 16, 2018: Clinical Respiratory Journal
Masahide Oki, Hideo Saka
BACKGROUND: Airway stenting has been reported to be useful for patients with malignant airway stenosis as a bridge to tumor-specific therapy, such as chemotherapy and radiation therapy, as well as palliative therapy. However, its role in patients with small-cell lung cancer (SCLC), the most aggressive lung cancer subtype, is unclear. We investigated the efficacy of airway stenting for patients with airway stenosis resulting from SCLC. METHODS: All stenting procedures were performed using both rigid and flexible bronchoscopes under general anesthesia...
April 16, 2018: Clinical Respiratory Journal
Joo Young Song, Eun Kyo Ha, Yoon Ho Sheen, Mi-Ae Kim, Seung Won Lee, Jung Won Yoon, Seung Jin Lee, Young-Ho Jung, Kyung Suk Lee, Jae-Cheul Ahn, Hye Mi Jee, Man Yong Han
INTRODUCTION: Allergic rhinitis (AR) is immunologically and morphologically related to disorders in the lower airway. We investigated the relationship between the anatomy of the intranasal cavity and small airway resistance in subjects with nonallergic rhinitis (NAR). METHODS: We enrolled 226 children who were 7 years old and participated in the Seongnam Atopy Project 2016. We evaluated nasal patency using acoustic rhinometry to measure the volume of the nasal cavity at 0 to 5 cm, and measured lung function of the lower airway using an impulse oscillometry system (IOS) and spirometry...
April 16, 2018: Clinical Respiratory Journal
Muhammed Batur, Erbil Seven, Merhamet Tanrıkulu, Selami Ekin, Serek Tekin, Tekin Yasar
OBJECTIVES: It is well known that pseudoexfoliative material deteriorates iris dilatation function. This material was also found in lung tissue. The aim of the study was to evaluate pulmonary function in patients with pseudoexfoliation. METHODS: This prospective study included 60 pseudoexfoliation syndrome patients without any pulmonary diseases and 52 age- and gender-matched controls without any pulmonary diseases. Patients were asked about their cigarette use and the presence of any systemic diseases such as diabetes mellitus, arterial hypertension, and asthma...
April 16, 2018: Clinical Respiratory Journal
A Maamar, S Chevalier, P Fillâtre, V Botoc, Y Le Tulzo, A Gacouin, J M Tadié
BACKGROUND: In-hospital outcomes following decisions of withholding or withdrawing in Intensive Care Unit (ICU) patients have been previously assessed, little is known about outcomes after ICU and hospital discharge. Our objective was to report the six-month outcomes of discharged patients who had treatment limitations in a general ICU and to identify prognostic factors of survival. METHODS: We retrospectively collected the data of patients discharged from the ICU for whom life support was withheld from 2009 to 2011...
April 16, 2018: Clinical Respiratory Journal
Oksana Kamenskaya, Irina Loginova, Alexander Chernyavskiy, Aleksander Edemskiy, Vladimir V Lomivorotov, Aleksander Karaskov
OBJECTIVE: The aim of our study was to investigate the prevalence of chronic obstructive pulmonary disease (COPD) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and examine their impact on the results of pulmonary thrombendarterectomy (PEA). METHODS: We enrolled 136 patients with CTEPH who scheduled for elective PEA. Pulmonary function tests (PFTs) including full-body plethysmography with bronchodilation test and lung diffusion capacity assessment were performed in all patients prior to surgery treatment...
April 16, 2018: Clinical Respiratory Journal
Kentaro Isoda, Takuya Kotani, Tohru Takeuchi, Junichi Konma, Takaaki Ishida, Kenichiro Hata, Kenichiro Otani, Hiroshi Fujiwara, Takeshi Shoda, Shigeki Makino, Shigeki Arawaka
OBJECTIVE: To identify a predictor of relapse in interstitial pneumonia (IP) in patients with anti-aminoacyl tRNA synthetase antibodies-positive dermatomyositis (ARS-DMIP). METHODS: This retrospective cohort study comprised 27 ARS-DMIP patients. We compared clinical and laboratory findings between the relapse and non-relapse groups during 2 years after treatment initiation to find predictors of relapse in IP. Candidate predictors were further assessed by analysing the relationship with the relapse of IP...
April 6, 2018: Clinical Respiratory Journal
Ausilia Elce, Ersilia Nigro, Monica Gelzo, Paola Iacotucci, Vincenzo Carnovale, Renato Liguori, Viviana Izzo, Gaetano Corso, Giuseppe Castaldo, Aurora Daniele, Federica Zarrilli
OBJECTIVE: cystic fibrosis (CF) is the most common inherited, life limiting condition among Caucasians. No healing therapy is currently available for patients with CF. The aim of the study was to define clinical, anthropometric and biochemical effects of regular, supervised physical exercise in a large cohort of patients with CF. MATERIALS AND METHODS: 59 adult patients with CF that performed regularly supervised physical exercise in the last three years in comparison to 59 sex and age matched sedentary patients with CF were included in the study...
March 30, 2018: Clinical Respiratory Journal
Rong Jiang, Yu Shi, Rui Zhang, Bigyan Pudasain, Lan Wang, Qin-Hua Zhao, Ping Yuan, Jian Guo, Chang-Tai Zhu, Jin-Ming Liu
Background:Although there exists potential risk of bleeding, extended "lifelong" conventional-intensity (international normalized ratio (INR): 2.0-3.0) warfarin anticoagulation is recommended for unprovoked venous thromboembolism (VTE) patients due to risk of recurrent VTE. Whether long-term low-intensity (INR: 1.5-2.0) warfarin therapy reduced the risk of major bleeding without substantially lowered antithrombotic efficacy is not well understood. The aim of this study was to perform a systematic review and meta-analysis to evaluate the risk-benefits of low-intensity warfarin therapy...
March 30, 2018: Clinical Respiratory Journal
María L Brance, Julio Miljevic, Raquel Tizziani, María E Taberna, Georgina P Grossi, Pablo Toni, Elina Valentini, Andrea Trepat, Julia Zaccardi, Juan Moro, Baltasar Finuci Curi, Norberto Tamagnone, Mariano Ramirez, Javier Severini, Pablo Chiarotti, Francisco Consiglio, Raúl Piñesky, Albertina Ghelfi, Jorge Kilstein, Eduardo Street, Dino Moretti, Viviana Oliveto, Marcelo Mariño, Jorge Manera, Lucas R Brun
INTRODUCTION: Community-acquired pneumonia (CAP) is the infectious disease with the highest number of deaths worldwide. Several studies have shown an association between vitamin D deficiency and increases susceptibility to respiratory tract infections. OBJECTIVE: The aim of this study was to evaluate the serum 25-hydroxyvitamin D (25OHD) levels in hospitalized adults in general room with CAP. MATERIALS AND METHODS: An observational study was carried out in 207 hospitalized adults of both sex with CAP over 18 years from Rosario city, Argentina (32º 52' 18''S) between July 2015 to June 2016...
March 23, 2018: Clinical Respiratory Journal
Chun Hua Xu, Chuan Zhen Chi, Qian Zhang, Yu Chao Wang, Wei Wang, Qi Yuan, Ping Zhan, Xiu Wei Zhang, Yong Lin
INTRODUCTION: Cripto-1 (CR-1) is a member of the epidermal growth factor (EGF)-CFC protein family, which is involved in tumor pathogenesis. OBJECTIVES: This study aimed to explore the diagnostic and prognostic value of serum CR-1 level in patients with non-small cell lung cancer (NSCLC). METHOD: Serum specimens from 312 NSCLC patients and 120 healthy controls were collected. Serum CR-1 level was measured using enzyme-linked immunosorbent assay (ELISA)...
March 23, 2018: Clinical Respiratory Journal
Elena-Mihaela Cordeanu, Waël Younes, Matthieu Canuet, Corina Mirea, Alix-Marie Faller, Anne-Sophie Frantz, Ayhan Daglayan, Sébastien Gaertner, Dominique Stephan
No abstract text is available yet for this article.
March 23, 2018: Clinical Respiratory Journal
Ahmed Omran, Samah Eesai, Mostafa Ibrahim, Sonya El-Sharkawy
BACKGROUND: Pneumonia is still a leading cause of illness and death in infants worldwide. Lung ultrasound (LUS) is emerging as an extremely valuable non-ionizing radiation diagnostic tool in diagnosis and follow up of multiple paediatric pulmonary diseases. OBJECTIVE: To assess the applicability of LUS in diagnosis and follow up of community acquired pneumonia (CAP) in Egyptian infants younger than 1-year old. METHODS: LUS and chest X-ray (CXR) were performed in 50 infants presented with clinical symptoms and signs suggestive of CAP within the first 6 hours of admission in our inpatient department, then follow up LUS was performed 5 days after admission...
March 23, 2018: Clinical Respiratory Journal
Aykut Cilli, Ozlem Cakin, Emine Aksoy, Feyza Kargın, Nalan Adıguzel, Zuhal Karakurt, Begum Ergan, Seda Mersin, Selen Bozkurt, Fatma Ciftci, Melike Cengiz
INTRODUCTION: An increased risk of cardiovascular complications has been defined in community-acquired pneumonia (CAP), but limited data is available for patients with severe CAP. OBJECTIVE: The aim of the present study was to define the prevalence, characteristics, risk factors and impact on mortality of acute cardiac events in patients with severe CAP during short and long term. METHOD: This investigation was a multicenter, retrospective cohort sudy of patients with severe CAP...
March 23, 2018: Clinical Respiratory Journal
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