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Clinical Respiratory Journal

E Pallari, G Lewison, R Sullivan
Background Newspapers are an important means for the communication medical research findings to policy-makers and the public, but may distort their views on the relative importance of research into, and burden from, different respiratory diseases. Methods A systematic search strategy based on respiratory-related keywords was developed and translated into 15European languages to identify relevant stories in 26 newspapers from eight countries in 2002-13. Details of the stories were recorded on Excel and coded based on the reported respiratory conditions (asthma, chronic obstructive pulmonary disease (COPD) and other) and research types...
August 5, 2017: Clinical Respiratory Journal
Mario Malerba, Alessandro Radaeli, Matteo Nardin, Enrico Clini, Giovanna Elisiana Carpagnano, Edoardo Sciatti, Francesca Salghetti, Ivano Bonadei, Fabio Platto, Enrico Vizzardi
INTRODUCTION: Patients with chronic obstructive pulmonary disease (COPD) have an increased risk of cardiovascular disease. The endothelial dysfunction likely plays a central role in increasing cardiovascular risk. OBJECTIVES: This cross-sectional, study investigated the prevalence and extent of endothelial dysfunction in patients with stable COPD. METHODS: Peripheral Arterial Tonometry (PAT) was measured by post-ischemic reactive hyperemia index (RHI) in 16 COPD patients, 16 healthy controls and 16 subjects with treated systemic arterial hypertension (AH) and analyzed with covariates condition (dyslipidemia, and medications)...
August 5, 2017: Clinical Respiratory Journal
Moussa Riachy, Georges Khayat, Ihab Ibrahim, Zeina Aoun, Georges Dabar, Taha Bazarbachi, Nadine Khalil, Bassem Habr
INTRODUCTION: No standardized sedation protocol is available for flexible bronchoscopy. OBJECTIVES: To evaluate the efficacy and safety of three regimens used for sedation during flexible bronchoscopy. METHODS: This randomized double-blind controlled trial assessed patients undergoing bronchoscopy and receiving lidocaine alone (C) or combined with dexmedetomidine (D) or alfentanil (A). Tolerance was assessed using the bronchoscopy score, and level of sedation was assessed using the Nursing Instrument for the Communication of Sedation...
August 5, 2017: Clinical Respiratory Journal
Hulya Sahin, Yelda Varol, Ilknur Naz, Fevziye Tuksavul
AIM: It has been demonstrated that long-term oxygen therapy increased exercise capacity, improved the quality of life, reduced hospitalization, and increased life expectancy in chronic hypoxemic COPD patients. The present study aims to evaluate the effectiveness of pulmonary rehabilitation (PR) in COPD patients receiving long-term oxygen therapy (LTOT) compared to COPD patients not receiving LTOT. MATERIAL AND METHOD: Chronic hypoxemic COPD patients using LTOT (LTOT group) and COPD patients not receiving LTOT (non-LTOT group) who participated in this study underwent a comprehensive 8-week outpatient PR program...
August 4, 2017: Clinical Respiratory Journal
Hiromasa Arai, Michihiko Tajiri, Yohei Kameda, Kimihisa Shiino, Kohei Ando, Koji Okudela, Munetaka Masuda
Purpose The aim of this study was to evaluate the efficacy of the Thopaz system, a new drainage system in management of general thoracic surgery, based on a review of our clinical practice and a comparison of the utility of the Thopaz device compared with a standard drainage system. Methods A review of 540 thoracic surgeries at our hospital was performed. These cases were divided into 275 treated with the Thopaz system from April 2014 to March 2015, and 265 treated with a standard system from April 2013 to March 2014...
August 4, 2017: Clinical Respiratory Journal
Adil Can Güngen, Belma Güngen, Yusuf Aydemir, Yeşim Guzey Aras, Hikmet Çoban, Hasan Düzenli
INTRODUCTION: Restless legs syndrome(RLS) is associated with sleep disorders. However, although sleep disturbance is prevalent in people with asthma, an insufficient number of studies have investigated the relationship between asthma and RLS. OBJECTIVES: We aimed to determine the extent of the presence of RLS, and the factors related to RLS, in people with asthma. METHODS: A total of 84 people with asthma and 51 healthy volunteers were enrolled...
August 4, 2017: Clinical Respiratory Journal
Soo A Kim, Brian B Koo, Do Eui Kim, Young Hwangbo, Kwang Ik Yang
OBJECTIVES: A limited number of studies have investigated the relationships among fatigue, insomnia and obstructive sleep apnea (OSA). This study evaluated the factors affecting fatigue severity in patients with OSA. METHODS: We investigated 633 OSA patients who were diagnosed by polysomnography. All patients completed sleep questionnaires including self-reported sleep duration, the Fatigue Severity Scale (FSS), the Korean version of Epworth Sleepiness Scale (K-ESS), Insomnia Severity Index (ISI), Korean version of Pittsburg Sleep Quality Index (K-PSQI) and Beck Depression Inventory-2 (BDI-2)...
August 4, 2017: Clinical Respiratory Journal
Sven Stieglitz, Sandhya Matthes, Ilona Kietzmann, Christina Priegnitz, Lars Hagmeyer, Winfried Randerath
OBJECTIVES: The number of ventilated patients is further increasing which leads to an increasing number of patients with weaning failure. In Germany, the treatment of patients with invasive out-of-hospital becomes more and more common. The aim of the study was to observe the outcome, the frequency and character of emergencies of patients with invasive out-of-hospital ventilation. METHODS: We conducted a prospective study over 1 year. 59 invasively ventilated patients living either at home or at nursing homes specialized in ventilator medicine were included...
August 4, 2017: Clinical Respiratory Journal
Michalis Agrafiotis, Efstathia Kotsifou, Vassilios Renessis, Anastassia Athanassiadou, Aekaterini Kousta, Diamantis Chloros
INTRODUCTION: Practical recommendations for the application of mouthpiece ventilation (MPV) are scarce. OBJECTIVE: To suggest a practice point for the management of patients started on MPV. CASE DESCRIPTION: A 73-year old gentleman with non-bulbar amyotrophic lateral sclerosis who was using his bilevel device for 16-18 hours per day was considered for MPV. He was started on an assist volume control mode with a tidal volume (Vt) of 0.9 L, delivered using a square flow shape over 1...
July 31, 2017: Clinical Respiratory Journal
Shiva Mansouri Hanis, Fatemeh Khosravi Shadmani, Salman Khazaei, Kamyar Mansori
No abstract text is available yet for this article.
July 31, 2017: Clinical Respiratory Journal
Giuseppe Fiorentino, Antonio M Esquinas
No abstract text is available yet for this article.
July 31, 2017: Clinical Respiratory Journal
Rosaria Casciaro, Stefano Costa, Patricia Dang, Fabio Majo, Mirco Ros
No abstract text is available yet for this article.
July 31, 2017: Clinical Respiratory Journal
Kin Iong Chan, Hong Ting Vong, Lai Fang Sin, Yuk Ching Yip, Xue Yun Zhong, Jian Ming Wen
Objectives We report the status of most common gene mutations in non-small cell lung carcinoma (NSCLC) in Macao, and explore the relationship between each gene mutation and clinicopathologic features and survival. Methods EGFR, KRAS and BRAF mutations were detected by PCR in 122 cases of NSCLC. ALK translocation and MET amplification were detected by fluorescence in situ hybridization (FISH). MET and thyroid transcription factor (TTF-1) were investigated by immunohistochemistry. Clinical data were collected for analyzing their correlation with the gene mutations...
July 29, 2017: Clinical Respiratory Journal
Bin Cao, Yi Huang, Dan-Yang She, Qi-Jian Cheng, Fan Hong, Xin-Lun Tian, Jin-Fu Xu, Jing Zhang, Yu Chen, Ning Shen, Hui Wang, Mei Jiang, Xiang-Yan Zhang, Yi Shi, Bei He, Li-Xian He, You-Ning Liu, Jie-Ming Qu
Community-acquired pneumonia (CAP) in adults is an infectious disease with high morbidity in China and the rest of the world. With the changing pattern in the etiological profile of CAP and advances in medical techniques in diagnosis and treatment over time, Chinese Thoracic Society of Chinese Medical Association updated its CAP guideline in 2016 to address the standard management of CAP in Chinese adults. Extensive and comprehensive literature search was made to collect the data and evidence for experts to review and evaluate the level of evidence...
July 29, 2017: Clinical Respiratory Journal
Seung Won Ra, Yong Soo Kwon, Sung Ho Yoon, Chi Young Jung, Ju Sang Kim, Hye Sook Choi, Seungsoo Sheen, Hun Gyu Hwang, Ji-Hyun Lee, Tae-Hyung Kim
BACKGROUND: Presence of purulent sputum during an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is considered sufficient indication for starting empirical antibiotics. We investigated the relationship between detection of potentially pathogenic bacteria (PPB) using sputum culture or polymerase chain reaction (PCR) and clinical response and sought the risk factors for PPB growth. METHODS: In 342 outpatients with AECOPD, we compared detection rates of H...
July 29, 2017: Clinical Respiratory Journal
Dmitry Tumin, Edwin J Jackson, Don Hayes
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is common but often underdiagnosed in the United States (US). Public health insurance coverage expansion may increase the prevalence of diagnosed COPD due to improved access to care and diagnosis. OBJECTIVE: We sought to determine the effects of Medicaid expansion on the prevalence of diagnosed COPD among low-income US adults. METHODS: The 2011-2015 Behavioral Risk Factor Surveillance System survey data were used to identify adults with annual household income <$50 000...
July 29, 2017: Clinical Respiratory Journal
Selda Telo, Gamze Kırkıl, Mutlu Kuluöztürk, Mehmet Balin, Figen Deveci
BACKGROUND AND AIMS: Asymmetric dimethylarginine (ADMA) decreases the levels of nitric oxide by inhibiting nitric oxide synthases. In this study, the possible role of ADMA in determining pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) patients was investigated. METHODS: Stable COPD patients who were admitted to pulmonology outpatient clinic were involved in the study. Forty healthy volunteers, with similar ages and sexes, were accepted as the control group...
July 29, 2017: Clinical Respiratory Journal
Georgia Karpathiou, Anna Batistatou, Panagiotis Boglou, Dimitrios Stefanou, Marios E Froudarakis
OBJECTIVES: To define the characteristics of necrotizing sarcoid granulomatosis (NGS) a very rare pulmonary disease hardly recognized by pulmonologists and pathologists. DATA SOURCE: PubMed was searched for the term necrotising or necrotizing sarcoid granulomatosis. STUDY SELECTION: All cases reported in the English literature were included. RESULTS: NGS is presented at all ages (range 8-68 years) with a median age of 42 years old...
July 29, 2017: Clinical Respiratory Journal
Evelina Pajediene, Indre Bileviciute-Ljungar, Danielle Friberg
OBJECTIVES: The purpose of this study was to detect treatable sleep disorders among patients complaining of chronic fatigue by using sleep questionnaires and polysomnography. METHODS: Patients were referred to hospital for investigations and rehabilitation because of a suspected diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The criteria for further referral to full-night polysomnography (PSG) were symptoms of excessive daytime sleepiness and/or tiredness in the questionnaires...
July 28, 2017: Clinical Respiratory Journal
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