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Journal of Breast Cancer

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https://www.readbyqxmd.com/read/28382106/erratum-validation-of-a-web-based-tool-to-predict-the-ipsilateral-breast-tumor-recurrence-ibtr-2-0-after-breast-conserving-therapy-for-korean-patients
#1
Seung Pil Jung, Sung Mo Hur, Se Kyung Lee, Sangmin Kim, Min-Young Choi, Soo Youn Bae, Jiyoung Kim, Min Kuk Kim, Won Ho Kil, Jun-Ho Choe, Jung-Han Kim, Jee Soo Kim, Seok Jin Nam, Jeoung Won Bae, Jeong Eon Lee
[This corrects the article on p. 97 in vol. 16, PMID: 23593089.].
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382105/erratum-magnetic-resonance-imaging-features-of-adenosis-in-the-breast
#2
Masoumeh Gity, Ali Arabkheradmand, Elham Taheri, Madjid Shakiba, Yassaman Khademi, Bijan Bijan, Mohammad Salehi Sadaghiani, Amir Hossein Jalali
[This corrects the article on p. 187 in vol. 18, PMID: 26155296.].
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382104/comment-on-histomorphological-factors-predicting-the-response-to-neoadjuvant-chemotherapy-in-triple-negative-breast-cancer
#3
COMMENT
Kadri Altundag
No abstract text is available yet for this article.
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382103/comment-on-chemotherapy-induced-left-ventricular-dysfunction-in-patients-with-breast-cancer
#4
COMMENT
Kadri Altundag
No abstract text is available yet for this article.
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382102/bilateral-triple-negative-invasive-breast-cancer-with-a-brca2-mutation-and-glioblastoma-a-case-report-and-literature-review
#5
Ali Raufi, Mohamed Alsharedi, Yousef Khelfa, Maria Tirona
Breast cancer is the second leading cause of death among women in North America. Glioblastoma is the most common primary malignant central nervous system tumor in adults. The majority of hereditary breast cancers are associated with deleterious mutations in the BRCA1 and BRCA2 genes. Although few case reports have described the incidence of glioblastoma in patients previously diagnosed with breast cancer, any association between BRCA2 mutations and glioblastoma has not been demonstrated to date. Herein, we report a woman who is a carrier of a familial BRCA2 mutation, and was previously diagnosed with triple-negative breast cancer (TNBC) and subsequently with a second primary TNBC and glioblastoma...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382101/brip1-fancj-mutation-analysis-in-a-family-with-history-of-male-and-female-breast-cancer-in-india
#6
Ananthapur Venkateshwari, David Wayne Clark, Pratibha Nallari, Cingeetham Vinod, Thangaraj Kumarasamy, Goverdhan Reddy, Akka Jyothy, Malladi Vijay Kumar, Raghuraman Ramaiyer, Komaraiah Palle
Male breast cancer (MBC) is a rare and poorly studied disease that is a growing global health problem. Interestingly, both the molecular basis of MBC and its histological profile are often quite distinct from the far more prevalent female breast cancer, emphasizing the need for increased focus on MBC. Here, we present a case report of an MBC patient from India with a strong familial history of breast cancer. This patient was normal for BRCA1/2 and many other common breast cancer-associated genes. However, upon further analysis, the individual was found to possess two mutations in the DNA helicase and tumor suppressor gene BRIP1, including a silent mutation at residue 879 as well as a P919S variant...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382100/patient-satisfaction-with-implant-based-breast-reconstruction-associated-with-implant-volume-and-mastectomy-specimen-weight-ratio
#7
Woo Yeol Baek, Il Hwan Byun, Young Seok Kim, Dae Hyun Lew, Joon Jeong, Tai Suk Roh
PURPOSE: Breast volume assessment is one of the most important steps during implant-based breast reconstruction because it is critical in selecting implant size. According to previous studies, there is a close relationship between the mastectomy specimen weight and resected breast volume. The aim of this study was to evaluate long-term patient satisfaction with implant-based breast reconstruction guided by the ratio of implant volume to mastectomy specimen weight. In doing so, we describe the ideal ratio for patient satisfaction...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382099/fertility-rates-in-young-korean-breast-cancer-patients-treated-with-gonadotropin-releasing-hormone-and-chemotherapy
#8
Isaac Kim, Jai Min Ryu, Hyun-June Paik, Sungmin Park, Soo Youn Bae, Se Kyung Lee, Jonghan Yu, Seok Won Kim, Seok Jin Nam, Jeong Eon Lee
PURPOSE: Gonadotropin-releasing hormone (GnRH) agonists have been used with adjuvant chemotherapy to protect ovarian function. However, there are no data on the actual pregnancy rates among young breast cancer patients receiving GnRH agonists and concurrent chemotherapy in Korea. METHODS: Among patients who underwent surgery from January 2002 to April 2012, premenopausal patients aged between 20 and 40 years were included in the analysis. We retrospectively reviewed clinicopathologic features (e...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382098/cardioprotective-effect-of-dexrazoxane-in-patients-with-her2-positive-breast-cancer-who-receive-anthracycline-based-adjuvant-chemotherapy-followed-by-trastuzumab
#9
In-Ho Kim, Ji Eun Lee, Ho-Joong Youn, Byung Joo Song, Byung Joo Chae
PURPOSE: We intended to determine whether dexrazoxane (DZR) is cardioprotective during administration of adjuvant anthracycline-based chemotherapy followed by a 1-year trastuzumab treatment. METHODS: The medical records of 228 patients who underwent surgical resection and received adjuvant chemotherapy with trastuzumab for human epidermal growth factor receptor type 2 (HER2)-positive breast cancer between January 2010 and December 2014 were reviewed. Approximately 25% of patients received DZR prior to each administration of doxorubicin during doxorubicin with cyclophosphamide (AC) chemotherapy...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382097/oncologic-outcomes-after-immediate-breast-reconstruction-following-total-mastectomy-in-patients-with-breast-cancer-a-matched-case-control-study
#10
Jai Min Ryu, Hyun-June Paik, Sungmin Park, Ha Woo Yi, Seok Jin Nam, Seok Won Kim, Se Kyung Lee, Jonghan Yu, Soo Youn Bae, Jeong Eon Lee
PURPOSE: The use of immediate breast reconstruction (IBR) following total mastectomy (TM) has increased markedly in patients with breast cancer. As the indications for IBR have been broadened and more breast-conserving surgery-eligible patients are undergoing IBR, comparing the oncologic safety between TM only and IBR following TM becomes more difficult. This study aimed to analyze the oncologic outcomes between TM only and IBR following TM via a matched case-control methodology. METHODS: A retrospective review was conducted to identify all patients who underwent TM between 2008 and 2014...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382096/a-prognostic-model-for-patients-with-triple-negative-breast-cancer-importance-of-the-modified-nottingham-prognostic-index-and-age
#11
Jeanny Kwon, Keun-Yong Eom, Tae Ryool Koo, Byoung Hyuck Kim, Eunyoung Kang, Sung-Won Kim, Yu Jung Kim, So Yeon Park, In Ah Kim
PURPOSE: Considering the distinctive biology of triple-negative breast cancer (TNBC), this study aimed to identify TNBC-specific prognostic factors and determine the prognostic value of the Nottingham Prognostic Index (NPI) and its variant indices. METHODS: A total of 233 patients with newly diagnosed stage I to III TNBC from 2003 to 2012 were reviewed. We retrospectively analyzed the patients' demographics, clinicopathologic parameters, treatment, and survival outcomes...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382095/prognostic-influence-of-bcl2-on-molecular-subtypes-of-breast-cancer
#12
Ki-Tae Hwang, Wonshik Han, Jongjin Kim, Hyeong-Gon Moon, Sohee Oh, Yun Seon Song, Young A Kim, Mee Soo Chang, Dong-Young Noh
PURPOSE: We aimed to reveal the prognostic influence of B-cell CLL/lymphoma 2 (BCL2) on molecular subtypes of breast cancer. METHODS: We analyzed 9,468 patients with primary breast cancer. We classified molecular subtypes according to the National Comprehensive Cancer Network (NCCN) and St. Gallen guidelines, mainly on the basis of the expression of hormonal receptor (HR), human epidermal growth factor receptor 2 (HER2), and Ki-67. RESULTS: Regarding NCCN classification, BCL2 was a strong favorable prognostic factor in the HR(+)/HER2(-) subtype (p<0...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382094/clinicopathologic-and-prognostic-significance-of-transducin-like-enhancer-of-split-1-protein-expression-in-invasive-breast-cancer
#13
Ji-Hye Lee, Sang Byung Bae, Mee-Hye Oh, Hyun Deuk Cho, Si-Hyong Jang, Soon Auck Hong, Junhun Cho, Sung Yong Kim, Sun Wook Han, Jong Eun Lee, Han Jo Kim, Hyun Ju Lee
PURPOSE: Transducin-like enhancer of split 1 (TLE1) is a member of the TLE family of transcriptional co-repressors that control the transcription of a wide range of genes. We investigated the prognostic significance of TLE1 protein expression in breast cancers by using immunohistochemistry and explored the relationship of TLE1 with clinicopathological parameters. METHODS: Immunohistochemistry was performed on 456 cases of breast cancer tiled on tissue microarrays...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382093/microrna-222-expression-as-a-predictive-marker-for-tumor-progression-in-hormone-receptor-positive-breast-cancer
#14
Song-Hee Han, Hyun Jeong Kim, Jae Moon Gwak, Mimi Kim, Yul Ri Chung, So Yeon Park
PURPOSE: The microRNA-221/222 (miR-221/222) gene cluster has been reported to be associated with the promotion of epithelial-mesenchymal transition (EMT), downregulation of estrogen receptor-α, and tamoxifen resistance in breast cancer. We studied the expression of miR-222 in human breast cancer samples to analyze its relationship with clinicopathologic features of the tumor, including estrogen receptor status, expression of EMT markers, and clinical outcomes. METHODS: Quantitative real-time polymerase chain reaction was performed to detect the expression of miR-222 in 197 invasive breast cancers...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382092/genetic-predisposition-of-polymorphisms-in-hmgb1-related-genes-to-breast-cancer-prognosis-in-korean-women
#15
Junsu Lee, Jaesung Choi, Seokang Chung, JooYong Park, Ji-Eun Kim, Hyuna Sung, Wonshik Han, Jong Won Lee, Sue K Park, Mi Kyung Kim, Sei-Hyun Ahn, Dong-Young Noh, Keun-Young Yoo, Daehee Kang, Ji-Yeob Choi
PURPOSE: The high mobility group box 1 (HMGB1) protein has roles in apoptosis and immune responses by acting as a ligand for receptor for advanced glycation end products (RAGE), Toll-like receptors (TLRs), and triggering receptor expressed on myeloid cells 1. In particular, HMGB1/RAGE is involved in tumor metastasis by inducing matrix metalloproteinase 2 (MMP2) and MMP9 expression. We investigated the associations between genetic variations in HMGB1-related genes and disease-free survival (DFS) and overall survival (OS) in Korean female breast cancer patients...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382091/inhibition-of-nicotinamide-phosphoribosyltransferase-induces-apoptosis-in-estrogen-receptor-positive-mcf-7-breast-cancer-cells
#16
Mohammad Alaee, Shahnaz Khaghani, Kiarash Behroozfar, Zahra Hesari, Seyedeh Sara Ghorbanhosseini, Mitra Nourbakhsh
PURPOSE: Tumor cells have increased turnover of nicotinamide adenine dinucleotide (NAD(+)), the main coenzyme in processes including adenosine diphosphate-ribosylation, deacetylation, and calcium mobilization. NAD(+) is predominantly synthesized in human cells via the salvage pathway, with the first component being nicotinamide. Nicotinamide phosphoribosyltransferase (NAMPT) is the key enzyme in this pathway, and its chemical inhibition by FK866 has elicited antitumor effects in several preclinical models of solid and hematologic cancers...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382090/detection-of-methylated-circulating-dna-as-noninvasive-biomarkers-for-breast-cancer-diagnosis
#17
REVIEW
Isabella Wai Yin Cheuk, Vivian Yvonne Shin, Ava Kwong
Internationally, breast cancer is the most common female cancer, and is induced by a combination of environmental, genetic, and epigenetic risk factors. Despite the advancement of imaging techniques, invasive sampling of breast epithelial cells is the only definitive diagnostic procedure for patients with breast cancer. To date, molecular biomarkers with high sensitivity and specificity for the screening and early detection of breast cancer are lacking. Recent evidence suggests that the detection of methylated circulating cell-free DNA in the peripheral blood of patients with cancer may be a promising quantitative and noninvasive method for cancer diagnosis...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28382089/basic-facts-of-breast-cancer-in-korea-in-2014-the-10-year-overall-survival-progress
#18
REVIEW
Eun Hwa Park, Sun Young Min, Zisun Kim, Chan Seok Yoon, Kyu-Won Jung, Seok Jin Nam, Se Jeong Oh, Seeyoun Lee, Byeong-Woo Park, Woosung Lim, Min Hee Hur
We, the Korean Breast Cancer Society (KBCS), present the facts and the trends of breast cancer in Korea in 2014. Data on the total number of newly diagnosed patients was obtained from the Korea Central Cancer Registry database, other data were collected from the KBCS online registry database, and the overall survival data of patients were updated from Statistics Korea. A total of 21,484 female patients were newly diagnosed with breast cancer in 2014. The crude incidence rate and the age-standardized incidence rate (ASR) of breast cancer in female patients, including carcinoma in situ, were 83...
March 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28053638/erratum-lentivirus-mediated-short-hairpin-rna-targeting-protein-phosphatase-4-regulatory-subunit-1-inhibits-growth-in-breast-cancer
#19
Yuying Qi, Tinghui Hu, Kai Lin, Renqing Ye, Zuodong Ye
[This corrects the article on p. 218 in vol. 18, PMID: 26472971.].
December 2016: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28053637/comment-to-patients-with-concordant-triple-negative-phenotype-between-primary-breast-cancers-and-corresponding-metastases-have-poor-prognosis
#20
COMMENT
Kadri Altundag
No abstract text is available yet for this article.
December 2016: Journal of Breast Cancer
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