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Journal of Complementary & Integrative Medicine

Kavitha Yuvaraj, Arumugam Geetha
Background Chronic pancreatitis (CP) is a persistent inflammation of the pancreas clinically presented with severe abdominal pain, progressive fibrosis, and loss of exocrine and endocrine functions. Inflammasomes, cytosolic multiprotein complexes which regulate the formation of proinflammatory cytokines, are influenced by various factors including heat shock proteins (HSPs). Morus alba L., or white mulberry root bark is a valued traditional Asian medicine with a diverse array of phytochemicals. The aim of this investigation was to define the modulatory action of methanolic extract of Morus alba root bark (MEMARB) on NLRP3 inflammasome, and HSPs in pancreas subjected to inflammatory insult...
October 18, 2018: Journal of Complementary & Integrative Medicine
Saeed Ahmad, Waheed Mumtaz Abbasi, Tayyeba Rehman
Background Belladonna and Pyrogenium are commonly used to treat fever in homeopathy. But in vivo antipyretic activity of these medicines is not reported yet. The study was conducted to evaluate the effectiveness of ultrahigh dilutions of Belladonna (Bell) and Pyrogenium (Pyro) in fever model of rabbits induced by Baker's yeast. Methods Healthy, local strain rabbits (♂ and ♀) were divided into seven groups (n=42): Normal control, negative control, standard control, pyro 1000c, pyro 200c, Bell 1000c and Bell 200c...
October 17, 2018: Journal of Complementary & Integrative Medicine
Arundhati Goley, A Mooventhan, N K Manjunath
Background Hydrotherapeutic applications to the head and spine have shown to improve cardiovascular and autonomic functions. There is lack of study reporting the effect of either neutral spinal bath (NSB) or neutral spinal spray (NSS). Hence, the present study was conducted to evaluate and compare the effects of both NSB and NSS in healthy volunteers. Methods Thirty healthy subjects were recruited and randomized into either neutral spinal bath group (NSBG) or neutral spinal spray group (NSSG). A single session of NSB, NSS was given for 15 min to the NSBG and NSSG, respectively...
October 17, 2018: Journal of Complementary & Integrative Medicine
Leila Riahi, Hanen Chakroun, Imen Klay, Ahmed Slaheddine Masmoudi, Ameur Cherif, Nejia Zoghlami
Background The Mentha rotundifolia L. (Lamiaceae family), is a medicinal herb used since the ancient times as an antiseptic, analgesic and anti-inflammatory agent. In the present work, metabolomic profiling of two Mentha rotundifolia L. ecotypes leaf tissues spontaneously growing in the North of Tunisia was achieved. Methods Phenolic contents (TPC, TFC and TTC) were assessed using colorimetric methods. Metabolomic profiling of leaf tissues extracts was assessed based on Gas Chromatography-Mass Spectrometry (GC/MS) analysis...
October 17, 2018: Journal of Complementary & Integrative Medicine
Naiara Coelho Ximenes, Manuel Alves Dos Santos Júnior, Germana Silva Vasconcelos, Kátia Cilene Ferreira Dias, Mércia Marques Jucá, Aline Holanda Silva, Luzia Kalyne Almeida Moreira Leal, Glauce Socorro Barros Viana, Francisca Cléa Florenço de Sousa, Silvânia Maria Mendes Vasconcelos
Background Schizophrenia is a chronic mental disorder, characterized by positive, negative and cognitive symptoms. In general, several plants have shown activity in diseases related to the central nervous system (e.g., Erythrina velutina (EEEV), also known as "mulungu"). For this reason, we aimed to investigate the effects of standardized ethanol extract obtained from the stem bark of EEEV on the schizophrenia-like behaviors induced by ketamine (KET) administration. Methods Swiss mice were treated with KET (20 mg/kg, i...
October 12, 2018: Journal of Complementary & Integrative Medicine
Saeed Ahmad, Samya Perveen, Muhammad Adeel Arshad, Tayyeba Rehman
Background Euphorbia granulata is herb of family Euphorbiaceae having several traditional uses. The aim of the study is to summarize reported nutritional and medicinal value along with ethnomedical records. Methods The papers on nutritional and medicinal value of E. granulata are collected from electronic search engines (Google Scholar, PubMed). Synonyms are confirmed from "The plant List." Results Pharmacological studies suggest that the extracts of E. granulata possess antioxidant, antibacterial, antifungal, diuretic, antiulcerative colitis and spasmolytic properties...
October 12, 2018: Journal of Complementary & Integrative Medicine
Hajar F Karaali, Ragaee R Fahmi, Jamilah M Borjac
Background Acetaminophen (APAP) is one of the most widely used drugs to treat pain. Its overdose is lethal causing liver and kidney failure. Nephrotoxicity and hepatotoxicity are mostly due to the overproduction of reactive oxygen species. Ocimum basilicum, known as basil, is a commonly used medicinal plant due to its versatile role as antibacterial, antifungal, and anti-oxidative. We aim in this study to investigate the preventive and protective effect of basil leaves aqueous extract against APAP-induced hepatorenal toxicity in BALB/c mice...
October 12, 2018: Journal of Complementary & Integrative Medicine
Amera Anjum, Arshiya Sultana
Background To compare the efficacy and safety of herbal decoction (pods of Cassia fistula Linn. and Arils of Myristica fragrans Houtt) with mefenamic acid in spasmodic dysmenorrhoea. Methods In this single-blind, prospective, parallel, standard controlled study, dysmenorrheic patients (n=64) were randomly allocated to receive herbal decoction (n=31) or mefenamic acid (n=33) for two consecutive menstrual cycles. Treatment group received 180 mL herbal decoction of post amaltas (Cassia fistula L pod's pericarp) (21 g), bisbasah (Myristica fragrans Houtt arils) (3 g) and qand siyah (jaggery) (30 g) which were orally administered at morning for 3 days before the expected start of menstruation...
October 12, 2018: Journal of Complementary & Integrative Medicine
Herney Andrés García-Perdomo, Laura M Montealegre Cardona, Maria Juliana Cordoba-Wagner, James A Zapata-Copete
Background To assess the effectiveness and harms of music to reduce anxiety and pain in cystoscopy. Methods We searched MEDLINE (OVID), EMBASE, LILACS and the Cochrane Central Register of Controlled Trials (CENTRAL) from inception to nowadays. We included clinical trials, involving the assessment of the effect of music in cystoscopy. The primary outcomes were pain and anxiety measured by any scale and the secondary outcomes were length of stay, physiological parameters (blood pressure or heart rate) and adverse effects...
October 12, 2018: Journal of Complementary & Integrative Medicine
Élida Mara Carneiro, Rafaela Miranda Carneiro Borges, Helia Morais Nomelini de Assis, Lohanna Gutierrez Bazaga, Janaíne Machado Tomé, Adriana Paula da Silva, Maria de Fátima Borges
Background Complementary Spiritist Therapy includes prayer, Spiritist "passe", fluid therapy (fluidic water or magnetized water), and spiritual education, among other therapeutic resources. The objective of this study was to evaluate the effects of Complementary Spiritist Therapy with conventional treatment on emotional status, muscle tension and wellbeing of hospitalized patients with HIV/AIDS. Methods Patients were randomly assigned into either the experimental (3 days [10 mins per day/session] of Complementary Spiritist Therapy alongside conventional treatment; n=20) or control (conventional treatment alone; n=21) group...
October 12, 2018: Journal of Complementary & Integrative Medicine
Ilana Levy, Samuel Attias, Lior Cohen, Nadav Stoppelmann, Dan Steinberger, Ofra Grimberg, Eran Ben-Arye, Ibrahim Matter, Gideon Sroka, Mostafa Somri, Elad Schiff
Background Postoperative pain is common in patients hospitalized in surgical departments, yet it is currently not sufficiently controlled by analgesics. Acupuncture, a complementary medical practice, has been evaluated for its benefits in postoperative pain with heterogeneous results. We tested the feasibility of a controlled study comparing the postoperative analgesic effect of acupuncture together with standard-of-care to standard-of-care only. Methods In this pilot non-randomized controlled study conducted at a tertiary medical center in Israel, patients received either acupuncture with standard-of-care pain treatment (acupuncture group) or standard-of-care treatment only (control group) following surgery...
October 12, 2018: Journal of Complementary & Integrative Medicine
Ika Fidianingsih, Nur Aisyah Jamil, Russy Novita Andriani, Wira Muhammad Rindra
Background A high prevalence of anxiety in the elderly often leads to decreased quality of life (QOL). A restrictive diet can increase the production of ketone bodies that encourage mood enhancement, neural protection and pain reduction. This study aimed to identify whether Dawood fasting could increase the QOL of the elderly by reducing anxiety. Methods This research was a quasi-experimental study involving a pretest-post-test control group design. The subjects were pre-elderly and elderly or healthy people aged more than 50, and a consecutive sampling method was employed...
October 12, 2018: Journal of Complementary & Integrative Medicine
Acharaporn Duangjai, Surasak Saokaew
Background Natural supplements and herbal medicines have been attracted to use for managing elevated cholesterol levels. Tiliacora triandra (Colebr.) Diels (TT) or Yanang (in Thai) is commonly used as an ingredient in various types of Thai foods. In this study, we investigated the effect of methanolic TT leaf extract on cholesterol absorption by measuring the uptake and the efflux of cholesterol and cholesterol micellar solubility. In addition, we tested the effect of TT leaf extract on pancreatic lipase activity...
October 12, 2018: Journal of Complementary & Integrative Medicine
Erika R Larson, Becky Kinkead, Sherry A Edwards, Pamela J Schettler, Boadie W Dunlop, Jeffrey J Rakofsky, Mark H Rapaport
Background The Protocol Training and Assessment Model (Model) was developed through collaboration between Emory University School of Medicine and Atlanta School of Massage to minimize intra- and inter-therapist variability for two research massage therapist (rMT) applied intervention arms in the Massage for Cancer-Related Fatigue (MCRF) early-phase study. The Model was followed to maintain and assess protocol integrity for the study's manualized Swedish massage therapy (SMT) and light touch (LT) interventions...
October 12, 2018: Journal of Complementary & Integrative Medicine
Sudabeh Ahmadidarrehsima, Reza Mohammadpourhodki, Hossein Ebrahimi, Maryam Keramati, Mostafa Dianatinasab
Background Fatigue is one of the most disturbing and the most common symptoms reported by patients dialyzed. There are methods available on complementary and alternative medicine, through which nurses can help patients to promote their health. Reflexology is a treatment which has a long history and is considered as one of the most popular and the most widespread methods of alternative medicine. In this study, the effects of foot reflexology and slow stroke back massage on the severity of fatigue in patients treated with hemodialysis were measured...
September 28, 2018: Journal of Complementary & Integrative Medicine
Kulwarang Wongwilairat, Orawan Buranruk, Wichai Eungpinichpong, Rungthip Puntumetakul, Somporn Kantharadussadee-Triamchaisri
No abstract text is available yet for this article.
August 22, 2018: Journal of Complementary & Integrative Medicine
Aida Mekhoukhe, Houda Kicher, Adidi Ladjouzi, Lamia Medouni-Haroune, Fatiha Brahmi, Sonia Medouni-Adrar, Khodir Madani
No abstract text is available yet for this article.
August 15, 2018: Journal of Complementary & Integrative Medicine
Ayokunle O Ademosun, Adeniyi A Adebayo, Ganiyu Oboh
Background Citrus peels have been reported useful in folk medicine for the management of cardiovascular diseases, but there is dearth of information on the possible mechanisms for their therapeutic action. The aim of this study was to investigate the effect of methanolic extracts from some citrus [lime (Citrus limon), tangerine (Citrus reticulata), shaddock (Citrus maxima)] peels on some enzymes relevant to the management of cardiovascular diseases [monoamine oxidase (MAO), phosphodiesterase-5 (PDE-5) and angiotensin-1-converting enzyme (ACE)]...
August 11, 2018: Journal of Complementary & Integrative Medicine
Meysam Zarezadeh, Ahmad Saedisomeolia, Masoud Khorshidi, Hamed Kord Varkane, Motahareh Makhdoomi Arzati, Mina Abdollahi, Mir Saeed Yekaninejad, Rezvan Hashemi, Mohammad Effatpanah, Niyaz Mohammadzadeh Honarvar
Aims Patients with type 2 diabetes mellitus (T2DM) are prone to cardiovascular disease (CVD) due to inflammation process and oxidative stress. ADMA (Asymmetric dimethylarginine) and ICAM-1 (inter-cellular adhesion molecule-1) play an important role in CVD pathogenesis. Ginger as an anti-oxidant and anti-inflammation can effect on these biomarkers. The aim of present study was to characterize the effect of ginger supplementation on ADMA and ICAM-1 serum levels in patients with T2DM. Methods The present study is a randomized double-blind clinical trial which is conducted among 45 diabetic patients (nginger=23, nplacebo=22)...
August 11, 2018: Journal of Complementary & Integrative Medicine
Zahi Arnon, Asnat Dor, Hadar Bazak, Samuel Attias, Shlomi Sagi, Shoshana Balachsan, Elad Schiff
Background Despite pharmacological interventions, labor pain and anxiety still remain a challenge, and can carry long-term psychological complications. The goal of this study was to assess the effect of reflexology on these symptoms and to explore the physical and psychological components of women's experience associated with this treatment. Methods This qualitative study was conducted in an Israeli university hospital that offers integrative medicine services. Reflexology was offered to laboring women in the hospital, by the medical staff...
July 19, 2018: Journal of Complementary & Integrative Medicine
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