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Journal of Complementary & Integrative Medicine

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https://www.readbyqxmd.com/read/29045235/the-aqueous-tuber-extract-of-pueraria-tuberosa-willd-d-c-caused-cytotoxic-effect-on-ht-29-cell-lines-with-down-regulation-of-nuclear-factor-kappa-b-nf-%C3%AE%C2%BAb
#1
Adeolu Alex Adedapo, Olusegun A Fagbohun, Christianah Dawurung, Ademola Adetokunbo Oyagbemi, Temidayo Olutayo Omobowale, Momoh Audu Yakubu
Background Pueraria tuberosa (Willd) D.C. (Fabaceae) tubers are already used in traditional medicine by Ayurvedic physicians for the management of fertility disorders, general weakness, and also as anti-ageing therapies. Other known pharmacological properties include: anti-hyperglycemics, hepatoprotective, anti-hyperlipidemic, diuretic, nutritive, and anti-fertility agents in male rats. Methods The anti-proliferative effect of the aqueous tuberous root extract of Pueraria tuberosa on vascular smooth muscle cells (VSMCs) and Human Colorectal Adenocarcinoma Cell lines (HT-29) was investigated using the Cell Titer 96 MTT Proliferation Assay where the viable cells were seeded at a density of 5 × 104 (100 µL/well)...
October 18, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28985183/the-effect-of-celery-apium-graveolens-l-on-fertility-a-systematic-review
#2
Wesam Kooti, Maryam Moradi, Khadijeh Peyro, Maedeh Sharghi, Fatima Alamiri, Milad Azami, Mohammad Firoozbakht, Mehri Ghafourian
Background Fertility and infertility problems are among the complex issues in medicine. The use of herbal products in the treatment of fertility has been considered as an alternative to synthetic drugs. Celery containing known compounds can have an impact on the fertility rate. The aim of this study was to do a systematic review on conducted studies in conjunction with the celery and reproduction. Methods Required papers were searched from databases like Science direct, PubMed, Scopus, and Springer. Keywords used in this study were "Apium graveolens L...
October 6, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28981445/comparison-of-honey-and-phenytoin-pht-cream-effects-on-intensity-of-pain-and-episiotomy-wound-healing-in-nulliparous-women
#3
Mohadesseh Lavaf, Masoumeh Simbar, Faraz Mojab, Hamid Alavi Majd, Mansoureh Samimi
Background This study investigates and compares the effect of phenytoin and honey cream on intensity of pain and episiotomy wound healing in nulliparous women. Methods This research was conducted by double-blinded randomized clinical trial method on 120 nulliparous women in three groups of phenytoin, honey and placebo. After delivery and episiotomy, mothers used a knuckle of the prescribed creams on their episiotomy area, every night until 10-night. Evaluation of wound healing using REEDA scale and pain intensity with numerical rating scale of pain took place within the first 24 h and after 7 and 14 days of delivery...
October 5, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28972943/kolaviron-and-garcinia-kola-attenuate-doxorubicin-induced-cardiotoxicity-in-wistar-rats
#4
Ademola Adetokunbo Oyagbemi, Temitayo Olutayo Omobowale, James Olukayode Olopade, Ebenezer Olatunde Farombi
Background The Garcinia kola seeds have been reported for its antibacterial, antioxidant, antidiabetic and also for its chemoprevention property. The use of doxorubicin as an anticancer drug has been accompanied with avalanche of side effects including cardiotoxicity. The aim of this study was to investigate the cardioprotective effect of Kolaviron and Garcinia kola and their mechanisms of action. Methods Sixty male rats (Wistar strain) were used in this study. They were divided into 6 groups (A-F) each containing 10 animals...
October 3, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28941354/modulatory-effect-of-caffeic-acid-on-cholinesterases-inhibitory-properties-of-donepezil
#5
Odunayo Michael Agunloye, Ganiyu Oboh
Background Donepezil hydrochloride commonly used in the management of Alzheimer's disease (AD), exhibiting its inhibitory effects on acetylcholinesterase and butyrylcholinesterase activity thereby enhance cognitive function. Caffeic acid member of hydroxycinnamic acid is widely present in human diet. This study aims to investigate influence of caffeic acid on acetylcholinesterase and butyrylcholinesterase inhibitory properties of donepezil (in vitro). Methods 5 mg of donepezil was dissolved in 50 mL distilled water while 10 mg of caffeic acid was dissolved in 100 mL distilled water...
September 22, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28915115/anti-arthritic-and-gastroprotective-activities-of-ardisia-crispa-root-partially-mediated-via-its-antioxidant-effect
#6
Roslida Abdul Hamid, Lau Moi Fong, Yeong Looi Ting
Background Ardisia crispa Thunb A.DC (Myrsinaceae), commonly known as "hen's eyes", has been traditionally used in treating various inflammatory diseases. The present study evaluated anti-arthritic, gastroprotective and antioxidant activities of Ardisia crispa root hexane extract (ACRH) in various animal models. Methods Anti-arthritic activity was evaluated in complete Freund adjuvant (CFA)-induced adjuvant arthritis and gastroprotective effect was studied in the ethanol-induced ulcer model in rats. ACRH was further isolated to yield quinone-rich fraction (QRF) and both were analyzed for their total phenolic content, total flavonoid content and antioxidant activities in various antioxidant assays...
September 14, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28915116/a-review-of-tunisian-medicinal-plants-with-anticancer-activity
#7
Wissem Aidi Wannes, Moufida Saidani Tounsi, Brahim Marzouk
Cancer is a major public health problem in the world. The use of the medicinal plants in cancer prevention and management is frequent in Africa, especially in Tunisia, and it is transmitted from generation to generation within cultures. Many previous studies showed that a wide range of Tunisian medicinal plants exerted cytotoxic and anticancer activity. A comprehensive review was conducted to collect information from scientific journal articles, including indigenous knowledge researches, about Tunisian medicinal plants used for the prevention and management of cancer...
September 13, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28865203/pharmacological-and-phytochemical-screening-of-palestinian-traditional-medicinal-plants-erodium-laciniatum-and-lactuca-orientalis
#8
Nidal Jaradat, Motasem AlMasri, Abdel Naser Zaid, Dua'a Ghazi Othman
BACKGROUND: Various epidemiological studies showed that herbal remedies containing polyphenols may protect against various diseases such as cancers, vascular diseases and inflammatory pathologies. Currently, such groups of bioactive compounds have become a subject of many antimicrobials and antioxidant investigations. Accordingly, the current study aimed to conduct biological and phytochemical screening for two Palestinian traditional medicinal plants, Erodium laciniatum and Lactuca orientalis...
September 1, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28850550/ameliorative-role-of-ethyl-acetate-fraction-of-methanolic-leaf-extract-of-camellia-sinensis-green-tea-on-streptozotocin-induced-diabetes-linked-testicular-hypofunction-in-albino-rat-a-dose-dependent-biochemical-and-genomic-transection-study
#9
Barnali Das, Baisakhi Biswas, Abhinandan Ghosh, Bhabani Prasad Pakhira, Debidas Ghosh
Background The present investigation focuses the diabetes-induced testicular hypofunction and its possible correction by the effective dose of ethyl-acetate fraction of methanolic extract of Camellia sinensis leaves through dose-dependent study in streptozotocin-induced diabetic rat. Methods The androgenic, spermiological, oxidative stress and apoptosis sensors along with testicular genomic sensors were evaluated in a dose-dependent fashion (50 mg or 100 mg or 200 mg/kg body weight). Activities of hepatic transaminases for toxicity assessment were also measured...
August 29, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28749782/erection-stimulating-anti-diabetic-and-antioxidant-properties-of-hunteria-umbellata-and-cylicodiscus-gabunensis-water-extractable-phytochemicals
#10
Ganiyu Oboh, Adeniyi A Adebayo, Ayokunle O Ademosun
Background Herbs have been used as an aphrodisiac since ages. This study was designed to investigate the effects of Hunteria umbellata (HU) seeds and Cylicodiscus gabunensis (CG) stem barks aqueous extracts on key enzymes relevant to erectile dysfunction (phosphodiesterase-5 and arginase) and type-2 diabetes (α-amylase and α-glucosidase). Methods In ascertaining the erectogenic and antidiabetic properties of the extracts, the effects of the extracts on activities of some enzymes relevant to erectile dysfunction (arginase and phosphodiesterase-5) and type-2 diabetes (α-amylase and α-glucosidase) were determined...
July 26, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28734114/effects-of-pomegranate-peel-extract-on-histopathology-testosterone-levels-and-sperm-of-testicular-torsion-detorsion-induced-in-adult-wistar-rats
#11
Mandana Beigi Boroujeni, Said Saied Shahrokhi, Mahdi Birjandi, Abolfazl Abbaszadeh, Fatemeh Beyranvand, Sakineh Hamoleh, Zohreh Zandbaf, Mohammadreza Gholami
Background In the present study, effects of pomegranate peel extract have been evaluated on decreasing the damage induced by testis torsion. Methods In this study, 30 adult Wistar rats were randomly divided into three groups of control, experimental (1) and experimental (2). CONTROL: no ischemia, received vehicle alone, exposed to sham operation. Experimental (1): Received the vehicle alone during ischemia followed by 60 days' reperfusion. Experimental (2): After performing ischemia reperfusion, 500 mg/kg of pomegranate peel extract has been used for 60 days...
July 22, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28704196/antioxidant-capacity-and-phenolic-content-of-two-algerian-mentha-species-m-rotundifolia-l-huds-m-pulegium-l-extracted-with-different-solvents
#12
Fatiha Brahmi, Farid Dahmoune, Nabil Kadri, Mohmed Chibane, Soufiane Dairi, Hocine Remini, Sonia Oukmanou-Bensidhoum, Lotfi Mouni, Khodir Madani
Background It is important to consider the optimum conditions and processing factors (like solvent type) influencing activity of plant antioxidants for utilization in food and biological systems. Methods The antioxidant capacity and phenolic content of two Mentha species, namely, Mentha pulegium L. (MP) and Mentha rotundifolia (L.) Huds (MR), were studied and six solvent systems were used. The total antioxidant capacity of the mint species extracts was evaluated using phosphomolybdenum method and the free radical-scavenging capacity by 2,2-diphenyl-1-picrylhydrazyl radical-scavenging assay...
July 8, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28665790/effects-of-quinine-on-gastric-ulcer-healing-in-wistar-rats
#13
Olasupo Stephen Adeniyi, Olubiyi Vincent Makinde, Emmanuel Titus Friday, Samuel Babafemi Olaleye
Background Quinine (QT) is an important anti-malarial drug; however, there is little information about its effects on the gut. Therefore, this study aimed to investigate the effects of a therapeutic dose of QT on the healing of gastric ulcer in rats. Methods Male Wistar rats weighing 150-200 g were divided into three groups: control rats without ulcer (group 1), ulcerated rats treated with 1 mL/kg (p.o.) normal saline (NS) (group 2), and ulcerated rats treated with 10 mg/kg (p.o.) QT (group 3). Ulcers were induced by serosal application of 80 % acetic acid to the stomach of rats anaesthetized with 50 mg/kg thiopentone sodium and treatment was given three times daily...
June 29, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28889731/comparative-evaluation-of-hypoglycemic-and-hypolipidemic-activity-of-various-extract-of-anogeissus-latifolia-bark-in-streptozotocin-induced-diabetic-rats
#14
Subramaniam Ramachandran, Thekkin Kattil Faisal, Jose Anjumary, Aiyalu Rajasekaran, Kuppusamy Asokkumar, Kuppusamy Annadurai, Ramasamy Arivukkarasu, Rajeev Kumar Sharma, Madhira Bhavani Shankar
Background Anogeissus latifolia Wall. (A. latifolia) bark has been traditionally used in the treatment of various diseases which includes diabetes and general debility. The present study was aimed to investigate the comparative hypoglycemic and hypolipidemic activity of various extracts of A. latifolia bark in streptozotocin-induced type 1 diabetic rats. Methods Acute toxicity was carried out at 2 g/kg dose of petroleum ether extract of A. latifolia bark (PEALB), chloroform extract of A. latifolia bark (CEALB) and methanol extract of A...
June 22, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28640753/mechanism-of-antihypertensive-effect-of-mucuna-pruriens-l-seed-extract-and-its-isolated-compounds
#15
Mohammad Yaseen Khan, Vimal Kumar
Background In the search of safe and effective lead molecules from natural sources, Mucuna pruriens (MP) L. (Fabaceae) seeds were utilized for exploring the antihypertensive potential. Traditionally, it is used as diuretic and hypotensive. Methods Bioassay-guided fractions were utilized for the isolation of active compounds by column chromatography. IC50 value, enzyme kinetics and inhibition mechanism were determined. In vivo time and dose-dependent hypotensive study followed by changes in mean arterial pressure (MAP) induced by angiotensin I (3 nmol/kg), angiotensin II (3 nmol/kg), and bradykinin (10 nmol/kg) in anesthetized rats was done...
June 21, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28665789/return-to-work-program-efficacy-with-self-regulation-therapy-srt%C3%A2-case-study-with-complex-trauma-and-concurrent-disorders
#16
Tara Miller
Background This study shows the efficacy of treating complex cases neurobiologically using Self-Regulation Therapy (SRT®) within the context of return to work goals. Case presentation This is a single case study of a 32-year-old white female. This case study follows a client with concurrent diagnoses of post-traumatic stress disorder (PTSD), bipolar disorder I and substance abuse over the course of 2 years of treatment with SRT®. Using SRT® as primary modality and Likert Scale self-report on the Zettl Scale of Dysregulation, psychiatric medication monitoring and pharmaceutical tracking, this study shows session summaries and progress...
June 16, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28731316/phytochemical-analysis-of-myrtus-communis-plant-conventional-versus-microwave-assisted-extraction-procedures
#17
Nadia Bouaoudia-Madi, Lila Boulekbache-Makhlouf, Nabil Kadri, Farid Dahmoune, Hocine Remini, Sofiane Dairi, Sonia Oukhmanou-Bensidhoum, Khodir Madani
Background Myrtle (Myrtus communis L) may constitute an interesting dietary source of health protective compounds. Microwave-assisted extraction (MAE) of total phenolic compounds (TPC) from myrtle leaf, stems, pericarp, and seeds was studied and the results were compared with those of the conventional method extraction (CME) in terms of extraction time. Methods Extraction yield/efficiency and antioxidant activity were measured using radical scavenging assay (DPPH•) and reducing power. Results The results show that the MAE was higher in terms of saving energy, extraction time (62 s) and extraction efficiency of bioactive compound compared to CME (2 h)...
June 10, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28731315/hypocholesterolemic-activity-of-cornelian-cherry-cornus-mas-l-fruits
#18
Fatemeh Hosseinpour, Tahoora Shomali, Mahmoud Rafieian-Kopaei
Background Lipid profile disturbances are important risk factors for cardiovascular events in patients with diabetes mellitus and finding safe and multifaceted agents is persuaded in this regard. This study aimed to evaluate the effect of cornelian cherry dried powder (CCDP) on serum lipid profile as well as liver antioxidant capacity, HMG-CoA reductase level and activity, and LDL receptor level in streptozotocin-induced diabetic rats. Methods Forty-eight male adult Wistar rats were randomly allocated into eight equal groups and were treated for 4 weeks as follows: negative control (normal rats, basic diet); positive control (diabetic rats, basic diet), T1 to T4 groups: diabetic rats fed with basic diet containing 0...
June 1, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28731313/an-innovative-mindfulness-and-educational-care-approach-in-an-adult-patient-affected-by-gastroesophageal-reflux-the-iara-model
#19
Andrea De Giorgio, Rita Maria Loscalzo, Marco Ponte, Anna Maria Padovan, Giuseppina Graceffa, Francesca Gulotta
Patients affected by gastroesophageal reflux disease (GERD) have a poor quality of life caused by several manifestations such as cough, asthma, laryngitis and dental erosion. The clinical conditions are highly disabling for patients and symptoms are difficult to manage. These conditions lead to many discomforts which contribute to an increase of the disease perception. For these reasons, it is important to improve the interventions on psychological aspects that ameliorate the patients' quality of life. The application of IARA model has proven useful to decrease GERD symptoms, distress and medication intake and to increase adherence to care, improving the patient's quality of life...
May 16, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28889732/effects-of-water-extract-of-curcuma-longa-l-roots-on-immunity-and-telomerase-function
#20
Min-Hsiung Pan, Jia-Ching Wu, Chi-Tang Ho, Vladimir Badmaev
Background Immunity and Longevity Methods A water extract of Curcuma longa (L.) [vern. Turmeric] roots (TurmericImmune™) standardized for a minimum 20 % of turmeric polysaccharides ukonan A, B, C and D was evaluated for its biological properties in in vitro tissue culture studies. Results The water extract of turmeric (TurP) exhibited induced-nitric oxide (NO) production in RAW264.7 macrophages. These results suggested the immunomodulatory effects of TurP. In addition, the polysaccharides up-regulated function of telomerase reverse transcriptase (TERT) equally to the phenolic compound from turmeric, curcumin...
May 12, 2017: Journal of Complementary & Integrative Medicine
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