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Dermatology Research and Practice

Reem Dina Matzen, Julie Zinck Leth-Espensen, Therese Jansson, Dennis Sandris Nielsen, Marianne N Lund, Steen Matzen
The mechanism behind the biologic actions of honey as a wound remedy has been intensively studied; however, there is no published data regarding any antibacterial effect of honey derived from Danish flora. We surveyed 11 honeys of various Danish floral sources for their antibacterial activity and compared them to a culinary processed commercial honey (Jakobsens) and a raw and a medical grade Manuka ( Leptospermum scoparium ) honey using the agar-well diffusion method. We tested the effect on three gram-positive bacteria (two strains of Staphylococcus aureus and one strain of Staphylococcus epidermidis ) and two gram-negative bacteria ( Pseudomonas aeruginosa and Escherichia coli )...
2018: Dermatology Research and Practice
Jorge Sánchez, Andres Sánchez, Ricardo Cardona
Background: Many patients with chronic spontaneous urticaria (CSU) identify different foods as triggers of their symptoms and frequently make dietary restrictions without enough information. Objective: To explore the diet habits of CSU patients and estimate the clinical impact of the foods most frequently reported to be suspect. Methodology: Patients were interrogated about their clinical history of urticaria. Skin prick test and sIgE serum were done for most frequently reported foods by patients...
2018: Dermatology Research and Practice
David G Li, Fan Di Xia, Jasmine Rana, Grace J Young, Forootan Alizadeh, Cara Joyce, Shinjita Das, Arash Mostaghimi
Variations in treatment modalities for skin growths contribute substantially to overall healthcare spending within dermatology. However, little is known regarding factors impacting patient decision-making when choosing a treatment modality. In this survey-based, cross-sectional study (n = 375, 81.9% response rate), we asked patients to rate the importance of different treatment parameters for a nonfacial skin growth, further classified into five domains: efficacy, appearance, financial impact, visit duration, and productivity...
2018: Dermatology Research and Practice
Mina Mirnezami, Hoda Rahimi
Background. Acne vulgaris is an inflammatory disease of pilosebaceous units which may cause permanent dyspigmentation and/or scars if not treated. Isotretinoin is recommended in the treatment of recalcitrant or severe acne, but it is associated with common adverse effects that frequently result in patients incompliance and discontinuation of the drug. The present study was designed to assess the efficacy of oral omega-3 in decreasing the adverse effects of isotretinoin. Materials and Methods. In this randomized double-blind clinical trial, a total of 118 patients with moderate or severe acne were randomly divided into two (case and control) groups...
2018: Dermatology Research and Practice
Teuku Alamsyah, Said Usman, Mutia Yusuf, Said Devi Elvin
Aceh Province had the highest rate of leprosy in Indonesia; in 2014, 436 new Multibacillary cases were reported. Nagan Raya was the District in Aceh with the highest number of cases; new cases in 2015 comprised 26 with Paucibacillary (PB) and 21 with Multibacillary (MB) with a total of 4.26% with Grade II disability. The phenomena of handling and treatment by the people in Nagan Raya involve treatment by traditional healers, "Tabib" , to treat the leprosy, with treatments known as Peundang locally...
2018: Dermatology Research and Practice
Dilia Giuggioli, Michele Colaci, Emanuele Cocchiara, Amelia Spinella, Federica Lumetti, Clodovero Ferri
[This corrects the article DOI: 10.1155/2018/1284687.].
2018: Dermatology Research and Practice
Philip M Stephens, Brian Martin, Ghazal Ghafari, James Luong, Vinayak K Nahar, Linda Pham, Jiangxia Luo, Marcelle Savoy, Manoj Sharma
Skin cancers are becoming a substantial public health problem in China. Fair skin and increased exposure to ultraviolet B (UVB) rays from the sun are among the most substantial risk factors for skin cancer development, thus making the Chinese people vulnerable to this group of diseases. The purpose of this article is to present a narrative review of the knowledge, attitudes, and practices (KAP) related to skin cancers within the Chinese population. A systematic electronic search of MEDLINE (PubMed), CINAHL, ScienceDirect, and Google Scholar databases yielded nine articles that met the inclusion criteria...
2018: Dermatology Research and Practice
Sukhontha Hasatsri, Anuphap Pitiratanaworanat, Suwit Swangwit, Chadaporn Boochakul, Chamaipond Tragoonsupachai
Good quality wound dressings should have exceptional properties for usage, such as being able to remove excess wound exudates, having rapid dehydration, and providing optimal water vapour permeability. This study evaluated and compared the morphological and physical properties of six different commercially absorbent wound dressings in Thailand: two hydrocolloids, two alginates, and two foams. These wound dressings are available in a variety of components and structures, some of which have a multilayer structure...
2018: Dermatology Research and Practice
Moonyza Akmal Ahmad Kamil, Azura Mohd Affandi
Introduction: Hidradenitis Suppurativa (HS) is a chronic inflammatory skin condition characterized by inflamed nodules, abscesses, sinus tracts, and scarring, which can occur in any skin containing folliculopilosebaceous units. We aim to identify the demographic and clinical characteristics and treatment modalities in patients with HS. Methods: A retrospective analysis involving records of patients diagnosed with HS in Hospital Kuala Lumpur from July 2009 to June 2016...
2018: Dermatology Research and Practice
Abbas Darjani, Rana Rafiei, Sareh Shafaei, Elahe Rafiei, Hojat Eftekhari, Narges Alizade, Kaveh Gharaei Nejad, Behnam Rafiee, Sara Najirad
Background: Cherry angioma is the most common type of acquired cutaneous vascular proliferation which would increase with aging due to some angiogenic factors but the exact pathogenesis is unknown. Usually angiogenic factors are synthesized in human body to compensate occlusive effects of atherogenic agents such as serum lipids. Our hypothesis was that increased levels of these angiogenic factors could be a trigger for development of cherry angioma. This study has been designed to compare frequency of dyslipidemia in subjects with and without cutaneous cherry angioma...
2018: Dermatology Research and Practice
Naveen Kumar, Pramod Kumar, Satheesha Nayak Badagabettu, Melissa Glenda Lewis, Murali Adiga, Ashwini Aithal Padur
Background: Difference in scar formation at different sites, in different directions at the same site, but with changes in the elasticity of skin with age, sex, and race or in some pathological conditions, is well known to clinicians. The inappropriate collagen syntheses and delayed or lack of epithelialization are known to induce scar formation with negligible elasticity at the site of damage. Changes in the elasticity of scars may be due to an unequal distribution of dermal collagen (C) and elastic (E) fibers...
2018: Dermatology Research and Practice
Susheera Chatproedprai, Vanvara Wutticharoenwong, Therdpong Tempark, Siriwan Wananukul
Aim: To determine the probable causative factors, clinical features, and treatment outcomes of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS-TEN overlap in children. Methods: A 20-year database review of all children diagnosed with SJS/TEN/SJS-TEN overlap at the King Chulalongkorn Memorial Hospital, Thailand. Results: 36 patients (M : F, 16 : 20) with the mean age of 9.2 ± 4.0 years were identified. There were 20 cases of SJS, 4 cases of SJS-TEN overlap, and 12 cases of TEN...
2018: Dermatology Research and Practice
Nastaran Namazi, Sahar Dadkhahfar
Impetigo herpetiformis (IH) is among rare dermatosis of pregnancy, which is currently considered as a form of generalized pustular psoriasis. It is diagnosed by characteristic lesions of erythematous patches and grouped pustules mostly in the third trimester of pregnancy and may have systemic associations. A variety of complications have been reported in the course of IH. Treatment of IH can be quite challenging, and a number of treatment options have been reported to be effective for the management.
2018: Dermatology Research and Practice
Azura Mohd Affandi, Iman Khan, Nooraishah Ngah Saaya
Background: Psoriasis is a chronic inflammatory skin disease affecting 2-3% of the general population. Aim: To evaluate the epidemiology and clinical characteristics of patients with psoriasis who seek treatment in outpatient dermatology clinics throughout hospitals in Malaysia. Materials and Methods: Data were obtained from the Malaysian Psoriasis Registry (MPR). All patients (aged 18 and above) who were notified to the registry from July 2017 to December 2017 were included in this study...
2018: Dermatology Research and Practice
Atena Barat, Michael J Goldacre, Trevor W Lambert
Objective: To report UK-trained doctors' career choices for dermatology, career destinations, and factors influencing career pathways. Methods: Multicohort multipurpose longitudinal surveys of UK-trained doctors who graduated between 1974 and 2015. Results: In all, 40,412 doctors (58% of graduates) responded in year 1, 31,466 (64%) in year 3, and 24,970 (67%) in year 5. One year after graduation, 1.7% of women and 0.6% of men made dermatology their first choice but by five years after graduation the respective figures were 1...
2018: Dermatology Research and Practice
Gia-Buu Tran, Nghia-Thu Tram Le, Sao-Mai Dam
Several herbal remedies have been used as topical agents to cure burn wound, one of the most common injuries in worldwide. In this study, we investigated the potential use of Cleistocalyx operculatus essential oil to treat the burn wound. We identified a total of 13 bioactive compounds of essential oil, several of which exhibited the anti-inflammatory and antimicrobial activities. Furthermore, the essential oil showed the antibacterial effect against S. aureus but not with P. aeruginosa. The supportive effect of essential oil on burn wound healing process also has been proven...
2018: Dermatology Research and Practice
Giuggioli Dilia, Colaci Michele, Cocchiara Emanuele, Spinella Amelia, Lumetti Federica, Ferri Clodoveo
Background: Systemic sclerosis (SSc) and localized scleroderma (LoS) are two different diseases that may share some features. We evaluated the relationship between SSc and LoS in our case series of SSc patients. Methods: We analysed the clinical records of 330 SSc patients, in order to find the eventual occurrence of both the two diseases. Results: Eight (2.4%) female patients presented both the two diagnoses in their clinical histories...
2018: Dermatology Research and Practice
Khadim Diongue, Mouhamadou Ndiaye, Mame Cheikh Seck, Mamadou Alpha Diallo, Aïda Sadikh Badiane, Daouda Ndiaye
Fusarium spp. represent 9 to 44% of onychomycoses caused by fungi other than dermatophytes. This retrospective study describes 17 cases of Fusarium onychomycosis diagnosed at the Laboratory of Parasitology and Mycology of Le Dantec University Hospital in Dakar, Senegal, from 2014 to 2016. It included all patients received in the laboratory for suspicion of onychomycosis between January 1, 2014, and December 31, 2016. Diagnosis was based on mycological examination including direct examination and culture. Mycological analysis was considered positive when direct examination and culture were positive after at least one repeat...
2017: Dermatology Research and Practice
Koussake Kombaté, Julienne Noude Técléssou, Bayaki Saka, Abla Sefako Akakpo, Koudjouka Odette Tchangai, Abas Mouhari-Toure, Garba Mahamadou, Waguena Gnassingbé, Aurel Abilogun-Chokki, Palokinam Pitché
Objective: This study aimed to determine the prevalence of and factors associated with self-medication in dermatology in Lomé, Togo. Methods: We conducted an analytical cross-sectional study from February to April 2016 in 2 dermatology departments in Lomé. Univariate and multivariate logistic regression models were carried out to identify possible factors associated with self-medication. Results: A total of 711 patients were included in the study...
2017: Dermatology Research and Practice
Christian Ottomann, Markus Küntscher, Bernd Hartmann, Vlado Antonic
Ischaemic insult in the skin flaps is a major problem in reconstructive surgery particularly in patients with diabetes mellitus. Here, we sought to investigate the effectiveness of ischaemic preconditioning (IP) on diabetic skin flaps in rat animal model. Hundred Wistar rats (90 streptozotocin treated animals and 10 nondiabetic controls) were used. Diabetes mellitus was confirmed by measuring glucose level in blood, HbA1c, and ketonuria. We used blood vessel clamping, hind limb tourniquet, and NO donors (Spermine/NO complex) to induce short-term ischaemia of tissues that will be excised for skin flaps...
2017: Dermatology Research and Practice
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