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Dermatology Research and Practice

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https://www.readbyqxmd.com/read/27899949/corrigendum-to-effect-of-narrow-band-ultraviolet-b-phototherapy-and-methotrexate-on-microrna-146a-levels-in-blood-of-psoriatic-patients
#1
Amal Abou El-Fadle, Asmaa M Ele-Refaei, Fatma M El-Esawy
[This corrects the article DOI: 10.1155/2015/145769.].
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27885324/clinical-outcome-of-a-novel-anti-cd6-biologic-itolizumab-in-patients-of-psoriasis-with-comorbid-conditions
#2
Vinay Singh
Psoriasis is a common, chronic, immune mediated, inflammatory disease of skin characterized by red patches enclosed with white scales and affects 2-3% of people in the world. Topical therapy, phototherapy, and systemic therapy were employed for management of disease from many last decades. However, long term uses of these agents are associated with unwanted effects and toxicities. Recently, Itolizumab has been developed as world's first anti-CD6 humanized monoclonal IgG1 antibody for the management of moderate-to-severe chronic plaque psoriasis in India...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27807445/comparison-of-european-standard-patch-test-results-of-330-patients-from-an-occupational-diseases-hospital
#3
Özge Gündüz, Aslı Aytekin, Engin Tutkun, Hınç Yılmaz
Background and Aim. Contact dermatitis (CD) is the most prevalent occupational skin disease with a significant impact on quality of life. Patch testing is used for the identification of responsible allergens which may improve protective and preventive measures in the workplace. Herein, we aim to identify the demographic characteristics and occupation of patients with early diagnosis of occupational CD and compare patch test results. Materials and Methods. The study included 330 patients referred to our clinic between April 2009 and April 2011 and who were patch-tested with 28-allergen European Standard Test...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27774100/recurrence-of-dysplastic-nevi-is-strongly-associated-with-extension-of-the-lesions-to-the-lateral-margins-and-into-the-deep-margins-through-the-hair-follicles-in-the-original-shave-removal-specimens
#4
Amin Maghari
Melanocytic nevi, including dysplastic or atypical nevi (DN), can recur or persist following shave removal procedures, and recurrence may resemble melanoma, both clinically and histologically (pseudomelanoma). Recurrence may originate from proliferation of the remaining neoplastic melanocytes following incomplete removal. The present study determines the rate and etiology of this event. A cross-sectional analysis of 110 excision specimens showing histological recurrence was performed, and these specimens were compared to the slides of the original shave specimens showing mildly atypical DN...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27738425/profile-of-skin-disorders-in-unreached-hilly-areas-of-north-india
#5
Deepak Dimri, Venkatashiva Reddy B, Amit Kumar Singh
Background. The pattern of skin morbidity in an area depends on climate, geography, socioeconomic status, nutrition, genetics, and habits of the community. Objective. The objective of the present study was to describe the morbidity profile of patients attending dermatology outpatient department in a tertiary care centre of Garhwal hills, North India. Methodology. This is a record based study carried out using the morbidity registers. Patient details, diagnosis, and treatment provided by physicians were documented in the morbidity register...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27437000/is-there-a-relation-between-abo-blood-groups-and-clinical-outcome-in-patients-with-pemphigoid-a-case-control-study
#6
Sedigheh Bakhtiari, Parviz Toosi, Somayyeh Azimi, Nafiseh Esmaili, Ali Montazami, Nasrin Rafieian
Background. Relationship between blood groups and dermatologic diseases remains controversial and was not yet fully elucidated nor explained clearly. The aim of this study was to examine if any relation exists between different types of pemphigoid diseases and ABO blood group. Methods. In this case-control study, 159 pemphigoid patients and 152 healthy matched-controls were evaluated. All blood group (including Rh status) data for the study was obtained from the hospital medical records. Statistical comparisons were completed with chi-square test and logistic regression...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27247564/pattern-of-pediatric-dermatoses-in-a-tertiary-care-hospital-of-western-nepal
#7
Yogesh Poudyal, Annu Ranjit, Santosh Pathak, Nagendra Chaudhary
Pediatric dermatoses are one of the most common presentations in a dermatology clinic and reflect the health and hygiene status of children. The incidence and severity of these skin lesions are influenced by geographical area, seasonal and cultural factors, and socioeconomic status. This study was done to show the prevalence of different pediatric dermatoses in a tertiary care hospital of Western Nepal. Chart reviews of children aged one day to 17 years, presenting to Universal Medical College Teaching Hospital, Nepal, from 1 September 2014 to 30 august 2015, were done...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27148363/a-comparison-between-the-effects-of-glucantime-topical-trichloroacetic-acid-50-plus-glucantime-and-fractional-carbon-dioxide-laser-plus-glucantime-on-cutaneous-leishmaniasis-lesions
#8
Fariba Jaffary, Mohammad Ali Nilforoushzadeh, Amirhossein Siadat, Elaheh Haftbaradaran, Nazli Ansari, Elham Ahmadi
Background. Cutaneous leishmaniasis is an endemic disease in Iran. Pentavalent antimonial drugs have been the first line of therapy in cutaneous leishmaniasis for many years. However, the cure rate of these agents is still not favorable. This study was carried out to compare the efficacies of intralesional glucantime with topical trichloroacetic acid 50% (TCA 50%) + glucantime and fractional carbon dioxide laser + glucantime in the treatment of cutaneous leishmaniasis. Methods. A total of 90 patients were randomly divided into three groups of 30 to be treated with intralesional injection of glucantime, a combination of topical TCA 50% and glucantime, or a combination of fractional laser and glucantime...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27143961/jumihaidokuto-shi-wei-ba-du-tang-a-kampo-formula-decreases-the-disease-activity-of-palmoplantar-pustulosis
#9
Megumi Mizawa, Teruhiko Makino, Chieko Inami, Tadamichi Shimizu
Palmoplantar pustulosis (PPP) is a chronic skin disease characterized by sterile intraepidermal pustules associated with erythematous scaling on the palms and soles. Jumihaidokuto is a traditional herbal medicine composed of ten medical plants and has been given to patients with suppurative skin disease in Japan. This study investigated the effect of jumihaidokuto on the disease activity in PPP patients (n = 10). PPP patients were given jumihaidokuto (EKT-6; 6.0 g per day) for 4 to 8 weeks in addition to their prescribed medications...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27143960/altered-levels-of-serum-zinc-and-cadmium-in-patients-with-chronic-vesiculobullous-hand-and-feet-dermatitis
#10
Swastika Suvirya, Alpna Thakur, S S Pandey, S K Tripathi, Durgesh Kumar Dwivedi
Micronutrients serve many important functions in our body and altered levels of heavy and trace metals are associated with cutaneous and systemic disorders. Vesicular palmoplantar eczema is an entity whose etiopathogenesis is a mystery. In this prospective case-noncase study blood levels of Zinc and Cadmium in 37 patients of chronic vesiculobullous hand dermatitis were estimated and compared with 40 noncases with similar age and gender distributions. Low serum Zinc levels were found in patients as compared to noncases...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27069472/effects-of-topical-emu-oil-on-burn-wounds-in-the-skin-of-balb-c-mice
#11
Mohammad Afshar, Reza Ghaderi, Mahmoud Zardast, Parvin Delshad
The goal of this study was to determine the effect of topical Emu oil on the healing of burn wounds and hair follicle restoration in superficial II-degree burns in the skin of Balb/c mice. Thirty-two male Balb/c mice with burns on the back of the neck were divided into two groups: The Emu oil group received topical Emu oil twice daily, whereas the control was left untreated. Skin biopsies were obtained on days 4, 7, 10, and 14 of the experiment. Then the specimens were viewed with Olympus SZX research microscope...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27069471/promising-option-for-treatment-of-striae-alba-fractionated-microneedle-radiofrequency-in-combination-with-fractional-carbon-dioxide-laser
#12
Farahnaz Fatemi Naeini, Shadi Behfar, Bahareh Abtahi-Naeini, Shima Keyvan, Mohsen Pourazizi
Background. A consistent treatment has not been proposed for treatment of Striae Alba (SA). The present study was designed to compare the fractionated microneedle radiofrequency (FMR) alone and in combination with fractional carbon dioxide laser (FMR + CO2) in the treatment of SA. Methods. Forty-eight pairs of SA from six patients were selected. Right or left SAs were randomly assigned to one of the treatment groups. The surface area of the SA before and after treatment and clinical improvement using a four-point scale were measured at the baseline, after one and three months...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27051415/production-of-a-self-aligned-scaffold-free-of-exogenous-material-from-dermal-fibroblasts-using-the-self-assembly-technique
#13
Stéphane Chabaud, Stéphane Bolduc
Many pathologies of skin, especially ageing and cancer, involve modifications in the matrix alignment. Such tissue reorganization could have impact on cell behaviour and/or more global biological processes. Tissue engineering provides accurate study model by mimicking the skin and it allows the construction of versatile tridimensional models using human cells. It also avoids the use of animals, which gave sometimes nontranslatable results. Among the various techniques existing, the self-assembly method allows production of a near native skin, free of exogenous material...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27047542/clinicoepidemiological-study-of-different-types-of-warts
#14
Shruti S Ghadgepatil, Sanjeev Gupta, Yugal K Sharma
Background. Warts are cutaneous and, sometimes, mucosal lesions caused by one of the several human papilloma viruses. Aim. Assessment of the clinicoepidemiological aspects of warts. Materials and Methods. One hundred consecutive patients of warts presenting to the department of our institution were assigned two broad locational groups: genital and nongenital warts, the latter subdivided into common, plane, palmoplantar, mosaic, and digitate/filiform. Results. Ninety had nongenital and 10 had genital warts in our study; common (42%), palmoplantar (20%), and plane (18%) were the common types of the nongenital warts...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27047541/methylchloroisothiazolinone-methylisothiazolinone-and-methylisothiazolinone-sensitivity-in-hungary
#15
Györgyi Pónyai, Ilona Németh, Erzsébet Temesvári
Background. Due to allowing of methylisothiazolinone (MI) in cosmetics, cleaning products, and paints, an epidemic of MI-hypersensitivity emerged. Patch testing Kathon CG® (3:1 mixture of methylchloroisothiazolinone and methylisothiazolinone, MCI/MI) does not correctly detect MI contact allergy, due to the low concentration of MI in the test material. Methods. A retrospective survey was performed to estimate the prevalence of MCI/MI hypersensitivity in 14693 patients tested consecutively between 1993 and 2014...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27042173/cutaneous-side-effects-of-braf-inhibitors-in-advanced-melanoma-review-of-the-literature
#16
REVIEW
Bilgen Gençler, Müzeyyen Gönül
The incidence of melanoma has recently been increasing. BRAF mutations have been found in 40-60% of melanomas. The increased activity of BRAF V600E leads to the activation of downstream signaling through the mitogen-activated protein kinase (MAPK) pathway, which plays a key role as a regulator of cell growth, differentiation, and survival. The use of BRAF inhibitors in metastatic melanoma with BRAF mutation ensures clinical improvement of the disease. Vemurafenib and dabrafenib are two selective BRAF inhibitors approved by the Food and Drug Administration (FDA)...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27019656/skin-protection-behaviors-among-young-male-latino-day-laborers-an-exploratory-study-using-a-social-cognitive-approach
#17
Javier F Boyas, Vinayak K Nahar, Robert T Brodell
Latino Day Laborers (LDLs) are employed in occupations where multiple work hazards exist. One such hazard is the overexposure to solar ultraviolet radiation for continuous periods of time. Regular sun exposure can put individuals at increased risk of developing skin cancers, especially without adequate protection. The purpose of this cross-sectional exploratory study was to use a social cognitive framework to assess skin protective behaviors among LDLs. A community-based nonrandom and purposive sample of LDLs was recruited in two states: Mississippi and Illinois...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/26981113/macular-amyloidosis-and-epstein-barr-virus
#18
Yalda Nahidi, Naser Tayyebi Meibodi, Zahra Meshkat, Narges Nazeri
Background. Amyloidosis is extracellular precipitation of eosinophilic hyaline material of self-origin with special staining features and fibrillar ultrastructure. Macular amyloidosis is limited to the skin, and several factors have been proposed for its pathogenesis. Detection of Epstein-Barr virus (EBV) DNA in this lesion suggests that this virus can play a role in pathogenesis of this disease. Objective. EBV DNA detection was done on 30 skin samples with a diagnosis of macular amyloidosis and 31 healthy skin samples in the margin of removed melanocytic nevi by using PCR...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/26904107/leprosy-continues-to-occur-in-hilly-areas-of-north-india
#19
Deepak Dimri, Arti Gupta, Amit Kumar Singh
Background. The aim of present study was to describe the profile of leprosy patients attending the outpatient department of dermatology in tertiary care hospital in Srinagar, Uttarakhand, North India. Methodology. This descriptive retrospective study. Patient data at the time of diagnosis were retrieved onto a predesigned proforma, which concerned the following variables at the time of registration: age, sex, and residence. Newly registered outpatients leprosy cases between 2009 and 2014 were included in the study...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/26904106/clinicoepidemiological-observational-study-of-acquired-alopecias-in-females-correlating-with-anemia-and-thyroid-function
#20
Kirti Deo, Yugal K Sharma, Meenakshi Wadhokar, Neha Tyagi
Alopecia can either be inherited or acquired; the latter, more common, can be diffuse, patterned, and focal, each having cicatricial and noncicatricial forms. This observational study of 135 cases in a semiurban Indian population aimed to detect the prevalence of various forms of acquired alopecia in females and correlate the same with levels of hemoglobin, serum ferritin, triiodothyronine, thyroxin, and thyroid stimulating hormone. The majority (84, 62.2%) of our cases of alopecia had telogen effluvium followed by female pattern alopecia (32, 23...
2016: Dermatology Research and Practice
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