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Journal of the American Society of Hypertension: JASH

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https://www.readbyqxmd.com/read/30219649/clinical-impact-of-dipping-and-nocturnal-blood-pressure-patterns-in-newly-diagnosed-never-treated-patients-with-essential-hypertension
#1
Eugenia Gkaliagkousi, Panagiota Anyfanti, Antonios Lazaridis, Areti Triantafyllou, Anastasios Vamvakis, Nikolaos Koletsos, Panagiotis Dolgyras, Stella Douma
The significance of nondipping and increased nighttime systolic blood pressure (SBP) in established hypertension is well defined. We investigated whether these factors alone or combined correlate with vascular damage in early-stage hypertension. Newly diagnosed, untreated hypertensives were classified as dippers and nondippers according to ambulatory blood pressure (BP). Twenty-four-hour urinary albumin excretion and markers of arterial stiffness (pulse wave velocity, augmentation index, central and peripheral pulse pressure, central BP) and atherosclerosis (carotid intima-media thickness) were assessed...
August 27, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30219648/normal-range-albuminuria-in-healthy-subjects-increases-over-time-in-association-with-hypertension-and-metabolic-outcomes
#2
Ayelet Grupper, Doron Schwartz, Shlomo Berliner, Moshe Shashar, Avishay Grupper, Roni Baruch, Idit F Schwartz, Talia Weinstein, Orit Kliuk Ben-Bassat, Ori Rogowski, David Zeltser, Itzhak Shapira, Shani Shenhar-Tsarfaty
Albuminuria is a prognostic factor for mortality and cardiovascular events, even at low levels. Changes in albumin excretion are associated with end-stage renal disease and hypertension (HTN) in cohorts including high-risk participants. We aimed to investigate the evolvement of albumin excretion in healthy individuals with normal kidney function and normoalbuminuria, and possible associations with HTN and metabolic outcomes. The study cohort consisted of 1967 healthy adults with normal kidney function (estimated glomerular filtration rate ≥ 90 mL/min/1...
August 23, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30181042/cardiovascular-safety-of-mirabegron-analysis-of-an-integrated-clinical-trial-database-of-patients-with-overactive-bladder-syndrome
#3
William B White, Emad Siddiqui, Tri Tat, Billy Franks, Carol R Schermer
Mirabegron is a β3 -adrenoreceptor agonist used for the treatment of overactive bladder syndrome. We evaluated the cardiovascular (CV) safety of mirabegron using pooled data from 13 studies. The analysis included 13,396 patients who received ≥1 dose of mirabegron (25 mg/50 mg) or comparator antimuscarinics (solifenacin 2.5 mg/5 mg/10 mg or tolterodine extended release 4 mg) as monotherapies, or placebo. We focused on changes in blood pressure and CV adverse events. Baseline CV risk factors had an imbalanced effect on subsequent CV adverse events...
August 10, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30150096/regarding-cadmium-body-burden-hypertension-and-changes-in-blood-pressure-over-time-results-from-a-prospective-cohort-study-in-american-indians
#4
LETTER
Tomoyuki Kawada
No abstract text is available yet for this article.
August 9, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30145322/association-between-subjective-sleep-duration-on-workdays-or-non-workdays-and-uncontrolled-blood-pressure-in-southern-china
#5
Lihua Hu, Yihua Zhou, Xiao Huang, Qian Liang, Chunjiao You, Wei Zhou, Juxiang Li, Ping Li, Yanqing Wu, Qinghua Wu, Zengwu Wang, Runlin Gao, Huihui Bao, Xiaoshu Cheng
OBJECTIVES: To examine the association between sleep duration on workdays or non-workdays and unsatisfactory blood pressure (BP) control in Southern China. METHODS: We analyzed 4370 hypertensive patients, including their self-reported sleep duration on workdays or non-workdays and their BP. Unsatisfactory BP control was defined as systolic BP of ≥140 mm Hg or diastolic BP of ≥90 mm Hg. Multivariate logistic regression analyses were performed to evaluate the association between sleep duration and unsatisfactory BP control...
August 3, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30104159/a-concise-predictive-nomogram-for-renal-artery-stenosis-in-selective-patients-undergoing-coronary-angiography
#6
Haojian Dong, Zhiqiang Nie, Wenhui Huang, Yuan Liu, Guang Li, Yanqiu Ou, Yingling Zhou, Jianfang Luo
As reported scoring systems of renal artery stenosis (RAS) screening were not easily validated, we further proposed a simple method to predict or rule out RAS in selective patients undergoing coronary angiography (CAG). After preliminary inclusive criterion (severe hypertension or atherosclerosis, flash pulmonary edema, or unexplained renal dysfunction), 503 and 158 consecutive patients undergoing renal arteriography at the timing of CAG were separately enrolled between 2012 and 2015, and 2016 and 2017 as the development and validation cohort...
July 25, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30115564/physical-activity-and-sedentary-behavior-thresholds-for-identifying-childhood-hypertension-and-its-phenotypes-the-healthy-growth-study
#7
Kalliopi Karatzi, George Moschonis, Sofia Botelli, Odysseas Androutsos, George P Chrousos, Christos Lionis, Yannis Manios
Hypertension phenotypes may represent differential pathophysiologic mechanisms and clinical impact, yet they have been poorly investigated. The study aimed to examine the associations of physical activity and sedentary behavior with hypertension phenotypes in a large group of Greek children and to identify thresholds regarding risk of hypertension. This was a cross-sectional study with a regionally representative sample of 2473 schoolchildren aged 9-13 years, with full data on physical activity and sedentary behavior indices, as well as arterial blood pressure measurements, physical examination, and anthropometry...
July 10, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30057253/arginine-impairs-endothelial-and-executive-function-in-older-subjects-with-cardiovascular-risk
#8
Joshua A Beckman, Shelley Hurwitz, Naomi D L Fisher
Neurovascular coupling, the relationship between cerebral blood flow and neuronal activity, is attenuated in patients with impaired executive function. We tested the hypothesis that peripheral vascular function may associate with executive function in older subjects with cardiovascular risk factors and that treatment with the antioxidant L-arginine would improve both vascular and executive function. Nineteen subjects with type 2 diabetes mellitus and/or controlled hypertension were enrolled. Subjects were treated with L-arginine or placebo for 4 days in a randomized, double-blinded, cross-over study...
July 10, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30056134/comparison-of-ankle-brachial-index-and-upstroke-time-in-association-with-target-organ-damage-the-northern-shanghai-study
#9
Shikai Yu, Yuyan Lu, Jing Xiong, Jiadela Teliewubai, Chen Chi, Hongwei Ji, Yiwu Zhou, Ximin Fan, Jun Zhang, Jacques Blacher, Jue Li, Yi Zhang, Yawei Xu
A recent study indicated that upstroke time per cardiac cycle (UTCC) in lower extremities is equivalent to ankle-brachial index (ABI) in diagnosing peripheral arterial disease and in predicting cardiovascular mortality. In this study, we aimed to compare ABI and UTCC in relation to target organ damage. A cohort of 1841 elderly participants from the Northern Shanghai Study was studied. ABI and UTCC were measured using VP-1000 device. Target organ damage including left ventricular hypertrophy and diastolic dysfunction, carotid intima-media thickness and plaque, carotid-femoral pulse wave velocity (CF-PWV), and renal damage, were evaluated by standardized methods...
June 30, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30031744/impact-of-intradialytic-blood-pressure-changes-on-cardiovascular-outcomes-is-independent-of-the-volume-status-of-maintenance-hemodialysis-patients
#10
Jungho Shin, Seongyup Yeo, Jun Young Hong, Jin Ho Hwang, Su Hyun Kim
Intradialytic systolic blood pressure (SBP) changes are related to the volume status; however, whether SBP change impacts on adverse outcomes depends on the volume status remains uncertain. We retrospectively investigated the relationship among intradialytic changes in SBP, cardiovascular outcomes, and volume status in maintenance hemodialysis patients. We determined SBP changes (ΔSBP) as postdialysis SBP minus predialysis SBP and volume status as the ratio of extracellular water to total body water (ECW/TBW) using bioelectrical impedance analysis...
June 28, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30220305/a-proposed-mechanism-for-the-berecek-phenomenon-with-implications-for-cardiovascular-reprogramming
#11
Richard N Re
Berecek et al reported in the 1990s that when spontaneously hypertensive rat (SHR) mating pairs were treated with captopril and the resulting pups were continued on the drug for 2 months followed by drug discontinuation, the pups did not develop full blown hypertension, and the cardiovascular structural changes associated with hypertension in SHR were mitigated. The offspring of the pups also displayed diminished hypertension and structural changes, suggesting that the drug therapy produced a heritable amelioration of the SHR phenotype...
September 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30220304/clinical-value-of-plasma-renin-activity-and-aldosterone-concentration-in-the-evaluation-of-secondary-hypertension-a-case-of-reninoma
#12
EDITORIAL
Musab S Hommos, Gary L Schwartz
No abstract text is available yet for this article.
September 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30219181/editor-s-page
#13
EDITORIAL
Daniel Levy
No abstract text is available yet for this article.
September 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30072147/bidirectional-association-between-nonalcoholic-fatty-liver-disease-and-hypertension-from-the-dongfeng-tongji-cohort-study
#14
Peiyi Liu, Yuhan Tang, Xiaoping Guo, Xinhong Zhu, Meian He, Jing Yuan, Youjie Wang, Sheng Wei, Weihong Chen, Xiaomin Zhang, Xiaoping Miao, Ping Yao
The relation between nonalcoholic fatty liver disease (NAFLD) and hypertension is not fully understood. To examine the effect of the change in NAFLD status on the risk of incident hypertension, and vice versa, 6704 eligible hypertension-free subjects and 9328 NAFLD-free subjects from the Dongfeng-Tongji cohort study at baseline were enrolled in the study. Among the hypertension-free subjects, development and persistence of NAFLD were associated with an increased odds ratio (OR) for incident hypertension (OR: 1...
September 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30054194/facebook-recruitment-of-chinese-speaking-participants-for-hypertension-education
#15
Phillip H Dunn, Benjamin K P Woo
Effective dissemination of health information to a desired population can be a challenging and expensive process, particularly to Chinese-Americans. Print and radio advertisements are limited by geographic, language, cost, and demographic barriers. The expense and efforts necessary to overcome these challenges can delay the distribution of knowledge and make it more expensive than necessary. The advent of web-based advertisements through media platforms such as Facebook offers a new method of reaching target audiences who can be both cost-effective and specific...
September 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30049626/misclassification-of-blood-pressure-of-vietnamese-adults-when-only-a-single-measurement-is-used
#16
Nga T T Tran, Christopher L Blizzard, Khue N Luong, Ngoc L V Truong, Bao Q Tran, Panagiota Veloudi, Petr Otahal, Mark Nelson, Costan Magnussen, Seana Gall, Tan V Bui, Velandai Srikanth, Thuy B Au, Son T Ha, Hai N Phung, Mai H Tran, Michele Callisaya, James Sharman
A single clinic measurement of blood pressure (BP) may be common in low- and middle-income countries because of limited medical resources. This study aimed to examine the potential misclassification error when only one BP measurement is used. Participants (n = 14,706, 53.5% females) aged 25-64 years were selected by multistage stratified cluster sampling from eight provinces, each representing one of the eight geographical regions of Vietnam. Measurements were made using the World Health Organization STEPS protocols...
September 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30042049/secondary-hypertension-due-to-a-juxtaglomerular-cell-tumor
#17
Igor Nunes, Tiago Santos, Joana Tavares, Lurdes Correia, João Coutinho, J M Braz Nogueira, Leonor Carvalho, J L Ducla Soares
Juxtaglomerular cell tumors are rare, generally benign, and they are one of the secondary surgically treatable causes of arterial hypertension. There are about 100 reported cases on literature, and the diagnosis is usually carried out based on a high clinic suspicion index, mostly in patients with hypokalemia and arterial hypertension. The diagnosis involves blood tests and imaging studies, but it is only definite with histopathological exam after surgical treatment. We present a case of a 22-year-old woman with resistant arterial hypertension and renal and cardiovascular target-organ lesions...
September 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30033124/simple-dietary-advice-reduces-24-hour-urinary-sodium-excretion-blood-pressure-and-drug-consumption-in-hypertensive-patients
#18
Natale Musso, Beatrice Carloni, Maria C Chiusano, Massimo Giusti
Sodium intake should be restricted to 100 mEq, that is, about 2.3 grams per day. Strict diets, however, are often cumbersome and seldom matched by rigorous compliance. We studied 291 patients on antihypertensive treatment, 240 of whom were instructed to avoid salty foods, such as cheese and cured meats, and to switch from regular bread to salt-free bread. The remaining 51 matched patients constituted a control group and received only generic dietary advice. Na[U]/24h, K[U]/24h, and office BP (automated repeated measurements) were recorded before dieting started and after 9 ± 1 weeks of dieting...
September 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30033123/aldosterone-inactive-matrix-gla-protein-and-large-artery-stiffness-in-hypertension
#19
Julio A Chirinos, Mayank Sardana, Amer Ahmed Syed, Maheshwara R Koppula, Swapna Varakantam, Izzah Vasim, Harold G Oldland, Timothy S Phan, Nadja E A Drummen, Cees Vermeer, Raymond R Townsend, Scott R Akers, Wen Wei, Edward G Lakatta, Olga V Fedorova
Vascular calcification leads to increased large artery stiffness. Matrix gla-protein (MGP) is a vitamin K-dependent protein that inhibits arterial calcification. Aldosterone promotes vascular calcification and stiffness, but the relationships between aldosterone, MGP, and arterial stiffness are unknown. We studied 199 adults (predominantly older men) with hypertension. We assessed the relationship between levels of dephospho-uncarboxylated MGP (dp-ucMGP), aldosterone, and carotid-femoral pulse wave velocity (CF-PWV) using standard regression and mediation analyses...
September 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/30219548/2017-acc-aha-aapa-abc-acpm-ags-apha-ash-aspc-nma-pcna-guideline-for-the-prevention-detection-evaluation-and-management-of-high-blood-pressure-in-adults-executive-summary-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on
#20
Paul K Whelton, Robert M Carey, Wilbert S Aronow, Donald E Casey, Karen J Collins, Cheryl Dennison Himmelfarb, Sondra M DePalma, Samuel Gidding, Kenneth A Jamerson, Daniel W Jones, Eric J MacLaughlin, Paul Muntner, Bruce Ovbiagele, Sidney C Smith, Crystal C Spencer, Randall S Stafford, Sandra J Taler, Randal J Thomas, Kim A Williams, Jeff D Williamson, Jackson T Wright
No abstract text is available yet for this article.
August 2018: Journal of the American Society of Hypertension: JASH
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