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Journal of the American Society of Hypertension: JASH

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https://www.readbyqxmd.com/read/28063813/assessment-of-vascular-function-in-low-socioeconomic-status-preschool-children-a-pilot-study
#1
Lama Ghazi, Tanja Dudenbostel, Daisy Xing, Deborah Ejem, Anne Turner-Henson, Cynthia Irwin Joiner, Olivia Affuso, Andres Azuero, Suzanne Oparil, David A Calhoun, Marti Rice, Fadi G Hage
Elevated brachial blood pressure (BP) in childhood tracks into adulthood. Central BP and measures of arterial stiffness, such as aortic augmentation index (AIx) and pulse wave velocity (PWV), have been associated with future cardiovascular disease. This pilot study assessed the feasibility of noninvasively measuring these parameters in preschool children and explored factors that may be associated with elevated BP in this age group. Brachial BP was measured using an electronic oscillometric unit (Dinamap PRO 100) and defined as elevated when systolic BP (SBP) and/or diastolic BP (DBP) was ≥ the 90th percentile for age, gender, and height...
December 24, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28089902/olmesartan-with-azelnidipine-versus-with-trichlormethiazide-on-home-blood-pressure-variability-in-patients-with-type-ii-diabetes-mellitus
#2
Emi Ushigome, Shinobu Matsumoto, Chikako Oyabu, Hidetaka Ushigome, Isao Yokota, Goji Hasegawa, Naoto Nakamura, Muhei Tanaka, Masahiro Yamazaki, Michiaki Fukui
The aim of the present study was to compare the effects of olmesartan combined with azelnidipine versus olmesartan combined with trichlormethiazide, on home blood pressure (BP) and pressure variability in type II diabetes mellitus patients using home BP telemonitoring system. We performed an open-label cross-over pilot study of 28 patients with type II diabetes mellitus. Patients received combination treatment with either olmesartan 20 mg plus azelnidipine 16 mg or olmesartan 20 mg plus trichlormethiazide 1 mg for more than 6 weeks each in a cross-over method...
December 22, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28089109/a-cross-sectional-study-of-physical-activity-and-arterial-compliance-the-effects-of-age-and-artery-size
#3
A Maleah Holland, Jeffrey S Martin, Christopher D Mattson, Keith R Lohse, Peter R Finn, Joel M Stager
Our study examined the relationship between habitual high levels of vigorous physical activity on large and small artery compliance via radial artery pulse wave analysis. Eighty-three healthy men (n = 44) and women (n = 39), aged 18-78 years, were recruited as habitually less active (light-to-moderate exercise ≤3 times/wk) or habitually highly active (vigorous exercise ≥5 times/wk). A multivariate analysis of variance revealed a significant interaction of age and activity level; habitual vigorous activity was associated with greater compliance in large and small arteries in older adults (40-78 years) and younger adults (18-22 years)...
December 22, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28087333/nicotinamide-nucleotide-transhydrogenase-activity-impacts-mitochondrial-redox-balance-and-the-development-of-hypertension-in-mice
#4
Igor Leskov, Amber Neville, Xinggui Shen, Sibile Pardue, Christopher G Kevil, D Neil Granger, David M Krzywanski
Oxidant stress contributes to the initiation and progression of hypertension (HTN) by enhancing endothelial dysfunction and/or causing perturbations in nitric oxide homeostasis. Differences in mitochondrial function may augment this process and provide insight into why age of onset and clinical outcomes differ among individuals from distinct ethnic groups. We have previously demonstrated that variation in normal mitochondrial function and oxidant production exists in endothelial cells from individuals of Caucasian and African-American ethnicity and that this variation contributes to endothelial dysfunction...
December 16, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28065708/an-exploratory-propensity-score-matched-comparison-of-second-generation-and-first-generation-baroreflex-activation-therapy-systems
#5
Rolf Wachter, Marcel Halbach, George L Bakris, John D Bisognano, Hermann Haller, Joachim Beige, Abraham A Kroon, Mitra K Nadim, Eric G Lovett, Jill E Schafer, Peter W de Leeuw
Baroreflex activation therapy (BAT) is a device-based therapy for patients with treatment-resistant hypertension. In a randomized, controlled trial, the first-generation system significantly reduced blood pressure (BP) versus sham. Although an open-label validation study of the second-generation system demonstrated similar BP reductions, controlled data are not presently available. Therefore, this investigation compares results of first- and second-generation BAT systems. Two cohorts of first-generation BAT system patients were generated with propensity matching to compare against the validation group of 30 second-generation subjects...
December 16, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28038989/increased-plasma-rbp4-concentration-in-older-hypertensives-is-related-to-the-decreased-kidney-function-and-the-number-of-antihypertensive-drugs-results-from-the-polsenior-substudy
#6
Marcin Majerczyk, Piotr Choręza, Maria Bożentowicz-Wikarek, Aniceta Brzozowska, Habibullah Arabzada, Aleksander Owczarek, Małgorzata Mossakowska, Tomasz Grodzicki, Tomasz Zdrojewski, Andrzej Więcek, Magdalena Olszanecka-Glinianowicz, Jerzy Chudek
Increased plasma retinol-binding protein 4 (RBP4), a novel adipokine, has been associated in previous studies with obesity, type 2 diabetes, dyslipidemia, hypertension (HT), atherosclerosis, and coronary artery disease. This study aimed to analyze the relationship between HT occurrence and its treatment, and plasma RBP4 concentrations in the older polish population. The study sample consisted of 1728 (890 men and 838 women) PolSenior study participants aged 65 years and older with available plasma samples and NT-proBNP values below 2000 pg/mL...
December 7, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28057444/redefining-beta-blocker-use-in-hypertension-selecting-the-right-beta-blocker-and-the-right-patient
#7
REVIEW
Samuel J Mann
Randomized controlled trials have concluded that the cardiovascular outcome of first-step treatment of hypertension with traditional vasoconstricting beta-blockers is inferior to treatment with other antihypertensive drug classes. Beta-blocker use is also associated with undesirable side effects. Consequently, some recent guidelines consider beta-blockers an inferior option for first-step treatment of hypertension. Despite this, beta-blockers are still widely prescribed, and likely overused, in the management of hypertension...
December 5, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28040405/extended-consensus-on-blood-pressure-variability-beyond-blood-pressure-for-management-of-hypertension
#8
EDITORIAL
Ram B Singh, Krasimira Hristova, Geir Bjørklund, Jan Fedacko, Salvatore Chirumbolo, Daniel Pella
No abstract text is available yet for this article.
November 25, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27988356/race-ethnicity-on-blood-pressure-control-after-ischemic-stroke-a-prospective-cohort-study
#9
Mai N Nguyen-Huynh, Nancy K Hills, Stephen Sidney, Jeffrey G Klingman, S Claiborne Johnston
Disparities in health care access and socioeconomic status (SES) have been associated with racial-ethnic differences in blood pressure (BP) control. We examined post-ischemic stroke BP in a multiethnic cohort with good health care access. We included all hypertensive patients (n = 2972) from a randomized quality improvement trial on secondary stroke prevention, conducted in 14 Kaiser Permanente hospitals in Northern California from 2004-2006 (QUISP). Average age 73.2 ± 12.2 years; 52% female, 66% non-Hispanic white, 14% African-American, 11% Asian, 8% Hispanic, and 1% other...
November 17, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27939526/sensitive-detection-of-hemodynamic-failure-during-orthostatic-stress-in-patients-with-diabetic-polyneuropathy-using-a-mini-laser-doppler-blood-flowmeter
#10
Masaki Goma, Masahiro Kaneshige, Sayaka Ichijo, Masashi Ichijo, Hideo Shindo, Nobuyuki Terada, Hiroshi Yokomichi, Zentaro Yamagata, Kenichiro Kitamura, Hiroki Shimura, Tetsuro Kobayashi
Autonomic dysfunction in diabetes is serious but often underestimated. The purpose of this study was to evaluate hemodynamics within the important initial phase just after standing, which cannot be evaluated by conventional instruments for orthostatic hypotension. Earlobe blood flow (EBF), which indirectly reflects the blood pressure response on standing, was evaluated using a mini laser Doppler flowmeter during standing from the sitting position in 58 healthy controls and 56 diabetic patients categorized as without (11), mild (27), and advanced diabetic polyneuropathy (18)...
November 17, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27939525/the-risk-of-developing-cardiovascular-disease-in-bangladesh-does-diabetes-mellitus-matter-which-socioeconomic-status-does-it-impact-a-cross-sectional-study
#11
G M Rabiul Islam
The elevation of blood pressure levels has been recognized as a determinant of the risk for several common cardiovascular diseases. This work explores the evidence of disparities in the form of association between hypertension and diabetes mellitus in different socioeconomic statuses (SESs) at household level. A population sample of 7561 individuals aged ≥35 years from the 2011 Bangladesh Demographic Health Survey (BDHS) was used for this study. Concentration indexes are used to measure the disparities of myocardial infarction and diabetes mellitus with SES...
November 17, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27866959/evaluating-the-risk-of-hypertension-according-to-the-metabolic-health-status-stratified-by-degree-of-obesity
#12
Jae-Hong Ryoo, Sung Keun Park, Chang-Mo Oh, Young-Jun Choi, Ju Youn Chung, Woo Taek Ham, Taegi Jung
Despite the accumulated evidence showing the significant association between hypertension and obesity, it remains unclear how metabolic healthy status of obesity have an impact on the development of hypertension. Thus, this study was to investigate the risk of hypertension according to the metabolic healthy status stratified by the degree of obesity. A cohort of 25,442 Korean men without hypertension at baseline was followed-up from 2005 to 2010. They were divided into the following 6 phenotypes according to their baseline metabolic health and obesity status: metabolically healthy normal weight (MH-NW), metabolically healthy overweight (MH-OW), metabolically healthy obese (MHO), metabolically unhealthy normal weight (MU-NW), metabolically unhealthy overweight (MU-OW), and metabolically unhealthy obese (MUO)...
November 2, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27876342/omega-3-fatty-acids-supplementation-improves-endothelial-function-and-arterial-stiffness-in-hypertensive-patients-with-hypertriglyceridemia-and-high-cardiovascular-risk
#13
Marcela A Casanova, Fernanda Medeiros, Michelle Trindade, Célia Cohen, Wille Oigman, Mario Fritsch Neves
Association between hypertriglyceridemia and cardiovascular (CV) disease is still controversial. The purpose of this study was to compare omega-3 and ciprofibrate effects on the vascular structure and function in low and high CV risk hypertensive patients with hypertriglyceridemia. Twenty-nine adults with triglycerides 150-499 mg/dL were divided into low (<7.5%) and high (≥7.5%) CV risk, randomized to receive omega-3 fatty acids 1800 mg/d or ciprofibrate 100 mg/d for 12 weeks. Treatment was switched after 8-week washout...
October 26, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27938855/management-of-severe-asymptomatic-hypertension-in-the-hospitalized-patient
#14
REVIEW
Sheryl Vondracek, Sarah Scoular, Toral Patel
Hypertension is common in the hospital setting. While the epidemiology, management, and outcomes of chronic hypertension are well defined, data and clinical guidance on the management of severe blood pressure elevations in the hospitalized patient are lacking. This article aims to review the literature related to the risks and benefits of managing severe asymptomatic hypertension in the hospitalized patient, summarize the concerns regarding managing severe asymptomatic hypertension with as-needed antihypertensive medication, and suggest alternative management strategies...
December 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27938854/the-influence-of-time-point-of-blood-pressure-measurement-on-the-outcome-in-hemodialysis-patients
#15
REVIEW
Yu-Chen Han, Bi-Cheng Liu
The blood pressure (BP) behaviors of hemodialysis (HD) population presented a unique pattern much different from that of the general population. This pattern is composed of chronic BP burden over interdialytic period and acute BP fluctuation during dialysis sessions. Peridialysis, interdialysis, and intradialysis are three routinely used time points to capture this complex BP behavior. However, BP at each time point was measured in various forms and conveyed different prognostic information. The measurement and interpretation of the tide-like BP behavior in HD population posed great challenge...
December 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27938853/opposing-effects-of-sodium-intake-on-uric-acid-and-blood-pressure-and-their-causal-implication
#16
Stephen P Juraschek, Hyon K Choi, Olive Tang, Lawrence J Appel, Edgar R Miller
Reducing uric acid is hypothesized to lower blood pressure, although evidence is inconsistent. In this ancillary of the DASH-Sodium trial, we examined whether sodium-induced changes in serum uric acid (SUA) were associated with changes in blood pressure. One hundred and three adults with prestage or stage 1 hypertension were randomly assigned to receive either the DASH diet or a control diet (typical of the average American diet) and were fed each of the three sodium levels (low, medium, and high) for 30 days in random order...
December 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27938852/electrocardiographic-measures-of-left-ventricular-hypertrophy-in-the-antihypertensive-and-lipid-lowering-treatment-to-prevent-heart-attack-trial
#17
Michael E Ernst, Barry R Davis, Elsayed Z Soliman, Ronald J Prineas, Peter M Okin, Alokananda Ghosh, William C Cushman, Paula T Einhorn, Suzanne Oparil, Richard H Grimm
Left ventricular hypertrophy (LVH) predicts cardiovascular risk in hypertensive patients. We analyzed baseline/follow-up electrocardiographies in 26,376 Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial participants randomized to amlodipine (A), lisinopril (L), or chlorthalidone (C). Prevalent/incident LVH was examined using continuous and categorical classifications of Cornell voltage. At 2 and 4 years, prevalence of LVH in the C group (5.57%; 6.14%) was not statistically different from A group (2 years: 5...
December 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27938851/from-the-editor
#18
EDITORIAL
Daniel Levy
No abstract text is available yet for this article.
December 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27865824/effect-of-placebo-groups-on-blood-pressure-in-hypertension-a-meta-analysis-of-beta-blocker-trials
#19
Marcel Wilhelm, Alexander Winkler, Winfried Rief, Bettina K Doering
Hypertension is often treated pharmacologically. Since there is evidence that the cardiovascular system is sensitive to placebo mechanisms, our aim was to conduct an effect size analysis of placebo groups in double-blinded randomized controlled parallel-group drug trials using beta-blockers to treat hypertensive patients. A comprehensive literature search via PubMed, PsycINFO, PSYNDEX, PQDT OPEN, OpenGREY, ISI Web of Knowledge, and the WHO International Clinical Trials Registry Platform provided the basis of our meta-analysis...
December 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27865823/gut-hormones-and-gut-microbiota-implications-for-kidney-function-and-hypertension
#20
REVIEW
Baris Afsar, Nosratola D Vaziri, Gamze Aslan, Kayhan Tarim, Mehmet Kanbay
Increased blood pressure (BP) and chronic kidney disease are two leading risk factors for cardiovascular disease. Increased sodium intake is one of the most important risk factors for development of hypertension. Recent data have shown that gut influences kidney function and BP by variety of mechanisms. Various hormones and peptides secreted from gut such as gastrin, glucocorticoids, Glucagon-like peptide-1 impact on kidney function and BP especially influencing sodium absorption from gut. These findings stimulate scientist to find new therapeutic options such as tenapanor for treatment of hypertension by blocking sodium absorption from gut...
December 2016: Journal of the American Society of Hypertension: JASH
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