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Journal of the American Society of Hypertension: JASH

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https://www.readbyqxmd.com/read/28528875/comparison-of-central-and-peripheral-hemodynamics-in-association-with-left-ventricular-diastolic-dysfunction-in-the-community-based-elderly-chinese
#1
Jing Xiong, Xuejing Yu, Shikai Yu, Bin Bai, Henry Xu, Hongwei Ji, Jiadela Teliewubai, Kai Wang, Chen Chi, Yuyan Lu, Yiwu Zhou, Ximin Fan, Jue Li, Yi Zhang, Yawei Xu
The aim of the study was to investigate the association of left ventricular diastolic dysfunction (LVDD) with central and peripheral hemodynamics. A total of 1599 community-based senior residents (aged ≥ 65 years) in northern Shanghai, China, were recruited as of August 2015. Echocardiography was performed for each participant using the MyLab30 Gold CV system. According to the recommendations from the American Society of Echocardiography, the ratio of E (peak early diastolic transmitral flow velocity) to E' (early diastolic lateral mitral annulus velocity) was assessed for the evaluation of LVDD...
April 27, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28479261/salt-and-essential-hypertension-pathophysiology-and-implications-for-treatment
#2
REVIEW
Michael A Garfinkle
Essential hypertension is common and is associated with significant morbidity and mortality. However, questions remain as to the exact physiological mechanisms underlying this disease. First, we discuss how essential hypertension may be largely a result of a maladaptation to a high-salt diet and that high blood pressure, rather than being an inactive side effect of high salt intake, may be an adaptive mechanism to improve salt secretion. Next, we explain how any physiological state that reduces urinary sodium concentrating ability may increase an individual's risk for salt-induced hypertension...
April 14, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28456497/smoking-before-isometric-exercise-amplifies-myocardial-stress-and-dysregulates-baroreceptor-sensitivity-and-cerebral-oxygenation
#3
Panagiota Anyfanti, Eleftheria Triantafyllidou, Stavros Papadopoulos, Areti Triantafyllou, Michalis G Nikolaidis, Antonios Kyparos, Ioannis S Vrabas, Stella Douma, Andreas Zafeiridis, Konstantina Dipla
This crossover study examined whether acute cardiovascular responses, baroreceptor sensitivity (BRS), and brain oxygenation during isometric exercise are altered after cigarette smoking. Twelve young, habitual smokers randomly performed a smoking and a control protocol, during which participants smoked one cigarette (0.9 mg nicotine) or a sham cigarette, before exercise. Testing involved baseline, a 5-minute smoking, a 10-minute post-smoking rest, 3-minute handgrip exercise (30% maximum voluntary contraction), and recovery...
April 14, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28457829/the-number-of-visits-and-blood-pressure-measurements-influence-the-prevalence-of-high-blood-pressure-in-adolescents
#4
Luciano Machado Ferreira Tenório de Oliveira, Alison Oliveira da Silva, Paula Rejane Beserra Diniz, Breno Quintella Farah, André Luiz Torres Pirauá, Antônio José de Lima Neto, Wallacy Milton do Nascimento Feitosa, Rafael Miranda Tassitano, Raphael M Ritti-Dias
The aim of this study was to analyze the influence of the number of visits and the number of blood pressure (BP) measurements on the prevalence of high blood pressure (HBP) in adolescents. A cross-sectional epidemiologic study with 481 adolescents (14-19 years old) selected using a random cluster sampling strategy. We measured the BP three times in a first visit. Adolescents with HBP performed subsequent visits. The final calculation of BP followed four strategies: the 1st measure, mean of 1st and 2nd measurements, mean of all three measurements, and averaging the 2nd and 3rd measurements...
April 13, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28456498/fibroblast-growth-factor-23-is-independently-associated-with-cardiac-mass-in-african-american-adolescent-males
#5
Bonita Falkner, Scott W Keith, Samuel S Gidding, Craig B Langman
Left ventricular hypertrophy has been documented in hypertensive adolescents and among some with prehypertension. Obesity also appears to be associated with cardiac mass, independent of blood pressure (BP). Fibroblast growth factor 23 (FGF23) is a novel biomarker positively associated with left ventricular hypertrophy in adults with and without kidney disease. The aim of this study was to determine if there was a significant and independent association of FGF23 with cardiac mass in a Black American adolescent cohort including both normotensive and prehypertensive participants with and without obesity...
April 12, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28412275/achieving-the-bptruth-emergency-department-hypertension-screening-and-the-centers-for-medicare-medicaid-services-quality-measure
#6
Elizabeth M Goldberg, Taneisha Wilson, Cory Saucier, Aaron M Brody, Phillip D Levy, Charles B Eaton, Roland C Merchant
In 2012, the Centers for Medicare & Medicaid Services (CMS) instituted a Physician Quality Reporting System measure for screening and referring patients with elevated blood pressure (BP). The aims of this study were to (1) assess the reliability of ED triage BP as a metric to establish when the CMS threshold (≥120/80 mm Hg), and other clinically relevant BP thresholds (≥140/90 and ≥160/100 mm Hg) have been met, using BP measured with a highly accurate device (BpTRU) in the emergency department as the gold standard; and (2) determine whether correct identification varies by gender, race, or triage acuity...
March 30, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28431936/galectin-3-mediates-the-pulmonary-arterial-hypertension-induced-right-ventricular-remodeling-through-interacting-with-nadph-oxidase-4
#7
Jingni He, Xiaohui Li, Hui Luo, Tangzhiming Li, Lin Zhao, Qiangqiang Qi, Yuwei Liu, Zaixin Yu
Pulmonary arterial hypertension (PAH) is a progressive disorder that affects both pulmonary vasculature and the heart. The response of the right ventricle (RV) to the increased afterload is an important determinant of the PAH final outcome. Galectin-3 (Gal-3), a novel biomarker in left cardiac remodeling, takes part in multiple pathophysiological processes including the inflammation, fibrosis, immunity, and oxidative stress. The levels of Gal-3 are elevated in PAH patients, although the exact mechanisms underlie the PAH-induced right ventricular structural changes remain unclear...
March 27, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28412277/the-association-of-endothelial-function-and-tone-by-digital-arterial-tonometry-with-mri-left-ventricular-mass-in-african-americans-the-jackson-heart-study
#8
Avnish Tripathi, Emelia J Benjamin, Solomon K Musani, Naomi M Hamburg, Connie W Tsao, Arti Saraswat, Ramachandran S Vasan, Gary F Mitchell, Ervin R Fox
Peripheral vascular endothelial dysfunction assessed by digital peripheral arterial tonometry (PAT) has been associated with risk for adverse cardiovascular events. We examined the relations of peripheral microvascular dysfunction and left ventricular mass in a community-based cohort of African Americans. We examined participants of the Jackson Heart Study who had PAT and cardiac magnetic resonance imaging evaluations between 2007 and 2013. Consistent with pertinent literature, left ventricular mass index (LVMI) was adjusted for body size by indexing to height(2...
March 27, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28412276/the-influence-of-hypertension-on-daytime-sleepiness-in-obstructive-sleep-apnea
#9
Helena Martynowicz, Robert Skomro, Paweł Gać, Grzegorz Mazur, Irena Porębska, Agnieszka Bryłka, Wojciech Nowak, Michał Zieliński, Anna Wojakowska, Rafał Poręba
Daytime sleepiness is a common symptom among hypertensive patients. The aim of this study was to determine subjective sleepiness assessed by Epworth Sleepiness Scale (ESS) and to asses sleep architecture in 304 patients with arterial hypertension. All patients underwent a standardized diagnostic overnight, polysomnography. The control group consisted of 67 normotensives. The hypertensive patients had a decreased sleep efficiency, mean and minimum oxygen saturation levels, and increased apnea/hypopnea index and oxygen desaturation index compared with normotensive patients...
March 27, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28411073/arterial-stiffness-and-elevated-left-ventricular-filling-pressure-in-patients-at-risk-for-the-development-or-a-previous-diagnosis-of-hf-a-subgroup-analysis-from-the-diast-chf-study
#10
Claus Lüers, Tobias Daniel Trippel, Sebastian Seeländer, Rolf Wachter, Gerd Hasenfuss, Ruhdja Lindhorst, Anna Bobenko, Kathleen Nolte, Burkert Pieske, Frank Edelmann
Left ventricular filling pressure (LVFP) is a marker for diastolic dysfunction and heart failure (HF) with preserved ejection fraction (pEF). The interaction between arterial stiffness (AS) and elevated LVFP has not been sufficiently investigated. In 257 patients with preserved left ventricular ejection fraction (mean age: 66 years, 53% female, mean left ventricular ejection fraction: 61%) and at least one cardiovascular risk factor (eg, hypertension and diabetes) for the development of HF or a previous diagnosis of HF, LVFP was estimated in accordance with the recommendations of the American Society of Echocardiography (elevated when E/e' ≥ 13, left atrial volume index ≥ 34 mL/m(2))...
March 27, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28411075/effect-of-gender-and-adiposity-on-in%C3%A2-vivo-vascular-function-in-young-african-americans
#11
Namrata Dass, Sindhu Kilakkathi, Brittaney Obi, Andrea Moosreiner, Shanthi Krishnaswami, Michael E Widlansky, Srividya Kidambi
The relationship between obesity and high blood pressure is not as strong among African Americans (AA) as compared to Caucasians. We designed the current study to determine the effect of adiposity on vascular endothelial function (a harbinger of hypertension) among young healthy AA without additional cardiovascular disease risk factors. A total of 108 AA subjects (46 women) between the ages of 18 and 45 years were recruited. All the subjects were normotensive, nonsmokers, and normoglycemic. Anthropometric and cardiovascular disease risk factor measurements (lipid, insulin resistance, and inflammatory markers) were obtained...
March 14, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28365237/contributions-of-aortic-pulse-wave-velocity-and-backward-wave-pressure-to-variations-in-left-ventricular-mass-are-independent-of-each-other
#12
Hamza Bello, Gavin R Norton, Imraan Ballim, Carlos D Libhaber, Pinhas Sareli, Angela J Woodiwiss
Aortic pulse wave velocity (PWV) and backward waves, as determined from wave separation analysis, predict cardiovascular events beyond brachial blood pressure. However, the extent to which these aortic hemodynamic variables contribute independent of each other is uncertain. In 749 randomly selected participants of African ancestry, we therefore assessed the extent to which relationships between aortic PWV or backward wave pressures (Pb) (and hence central aortic pulse pressure [PPc]) and left ventricular mass index (LVMI) occur independent of each other...
March 14, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28411074/low-dose-sustained-release-deoxycorticosterone-acetate-induced-hypertension-in-bama-miniature-pigs-for-renal-sympathetic-nerve-denervation
#13
Wenzheng Han, Weiyi Fang, Qian Gan, Shaofeng Guan, Yanjie Li, Ming Wang, Kaizheng Gong, Xinkai Qu
Recently, the effectiveness of renal sympathetic nerve denervation for treatment of hypertension has been doubted after SYMPLICITY HTN-3 trial. An ideal animal model is still unavailable for preclinical study about catheter-based renal sympathetic nerve denervation for treatment of hypertension. Traditional high-dose deoxycorticosterone acetate (DOCA)-induced hypertension pig model has some problems due to extensive end-organ damage. Based on the similarity in the anatomic characteristics of renal artery between pigs and humans, this study was undertaken to establish a low-dose sustained-release DOCA-induced hypertension model in pigs...
March 2, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28454770/from-the-editor
#14
EDITORIAL
Daniel Levy
No abstract text is available yet for this article.
March 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28291672/the-relationship-of-alcohol-consumption-with-left-ventricular-mass-in-people-35%C3%A2-years-old-or-older-in-rural-areas-of-western-china
#15
Yunjing Yang, Nan Zhang, Wei Huang, Rui Feng, Panpan Feng, Jun Gu, Gang Liu, Han Lei
The aim of this study was to investigate the association between alcohol intake and left ventricular mass (LVM) independent of the effects of blood pressure and other factors in rural areas of Western China. The present study included 1007 subjects (487 men and 520 women) aged ≥35 years from the Tongan district, Chongqing, China. The quantity and frequency of alcohol consumption were estimated from a validated questionnaire. Echocardiography was used to assess left ventricular dimensions. Drinkers was associated with higher LVM compared with nondrinkers (β = 6...
February 20, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28285829/clinic-and-ambulatory-blood-pressure-in-a-population-based-sample-of-african-americans-the-jackson-heart-study
#16
S Justin Thomas, John N Booth, Samantha G Bromfield, Samantha R Seals, Tanya M Spruill, Gbenga Ogedegbe, Srividya Kidambi, Daichi Shimbo, David Calhoun, Paul Muntner
Blood pressure (BP) can differ substantially when measured in the clinic versus outside of the clinic setting. Few population-based studies with ambulatory blood pressure monitoring (ABPM) include African Americans. We calculated the prevalence of clinic hypertension and ABPM phenotypes among 1016 participants in the population-based Jackson Heart Study, an exclusively African-American cohort. Mean daytime systolic BP was higher than mean clinic systolic BP among participants not taking antihypertensive medication (127...
February 16, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28302456/association-between-modified-shuttle-walk-test-and-cardiorespiratory-fitness-in-overweight-obese-adults-with-primary-hypertension-exerdiet-hta-study
#17
Borja Jurio-Iriarte, Ilargi Gorostegi-Anduaga, G Rodrigo Aispuru, Javier Pérez-Asenjo, Peter H Brubaker, Sara Maldonado-Martín
The aims of the study were to evaluate the relationship between Modified Shuttle Walk Test (MSWT) with peak oxygen uptake (V˙O2peak) in overweight/obese people with primary hypertension (HTN) and to develop an equation for the MSWT to predict V˙O2peak. Participants (N = 256, 53.9 ± 8.1 years old) with HTN and overweight/obesity performed a cardiorespiratory exercise test to peak exertion on an upright bicycle ergometer using an incremental ramp protocol and the 15-level MSWT. The formula of Singh et al was used as a template to predict V˙O2peak, and a new equation was generated from the measured V˙O2peak-MSWT relationship in this investigation...
February 7, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28242179/anthropometric-profile-of-hong-kong-children-and-adolescents-the-wellness-population-of-youth-study
#18
Regina L T Lee, Paul H Lee, Daniel M Y Sze, Wai Tong Chien
Childhood obesity has been a public health concern increasingly. We investigated the age- and sex-specific body mass index (BMI), blood pressure level, and other obesity measures in Hong Kong children and adolescents. We used the data from Wellness Population of Youth Study, a health examination for anthropometric measurements among children and adolescents (aged 9-15 years) in Hong Kong, conducted in Oct 2012-Jun 2013 (n = 4410). Anthropometric measures including weight, height, pulse, systolic and diastolic blood pressures, triceps and scapula skinfold thickness, and waist circumference were measured following universal standard protocol...
February 6, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28238630/primate-response-to-angiotensin-infusion-and-high-sodium-intake-differ-by-sodium-lithium-countertransport-phenotype
#19
Kimberly D Spradling-Reeves, Robert E Shade, Joseph R Haywood, Laura A Cox
An increased level of sodium-lithium countertransport (SLC) activity has been associated with salt-sensitive hypertension. Previous findings have suggested that dysregulation of the renin-angiotensin-aldosterone system (RAAS) may be involved in the mechanism linking elevated SLC activity and hypertension. Therefore, baboons with different levels of SLC activity were given two diets differing in sodium content, with and without an angiotensin II (ANG II) infusion, to investigate the relationship between SLC activity, the RAAS, and physiological regulation by sodium...
February 3, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28236585/the-importance-of-genetic-counseling-and-genetic-screening-a-case-report-of-a-16-year-old-boy-with-resistant-hypertension-and-severe-hypokalemia
#20
Ze-Min Kuang, Ying Wang, Jia-Jie Wang, Jing-Hua Liu, Rong Zeng, Qi Zhou, Zhen-Qiu Yu, Long Jiang
Liddle's syndrome, an autosomal dominant form of monogenic hypertension, is characterized by salt-sensitive hypertension with early penetrance, hypokalemia, metabolic alkalosis, suppression of plasma rennin activity and aldosterone secretion, and a clear-cut response to epithelial sodium channel blockers but not spironolactone therapy. Here, we describe the case of a 16-year-old boy patient with resistant hypertension (maintain 170-180/100-110 mm Hg after administration four kinds of antiypertensive drugs) and severe hypokalemia...
February 3, 2017: Journal of the American Society of Hypertension: JASH
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