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Journal of the American Society of Hypertension: JASH

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https://www.readbyqxmd.com/read/29146156/latest-guidelines-for-hypertension-adopt-and-adapt
#1
EDITORIAL
C Venkata S Ram
No abstract text is available yet for this article.
November 13, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29146158/plasma-microrna-155-5p-is-increased-among-patients-with-chronic-kidney-disease-and-nocturnal-hypertension
#2
Dominika Klimczak, Marek Kuch, Tomasz Pilecki, Dorota Żochowska, Agnieszka Wirkowska, Leszek Pączek
MicroRNAs play multiple roles in the regulation of blood pressure (BP). Nevertheless, to date, no study has assessed the association between microRNA plasma expression and BP control in chronic kidney disease (CKD) patients. Given this background, we evaluated the plasma expression of miR-155-5p, a translational inhibitor of angiotensin receptor type I, in CKD patients, to determine the association between miR-155-5p level and BP control. In this single-center cross-sectional study, we analyzed the miR-155-5p concentration by quantitative reverse transcriptase polymerase chain reaction using the U6 snRNA as a reference gene and 24-hour ambulatory blood pressure monitoring in CKD patients (stage ≥2) in relation to a control group of healthy age-matched and gender-matched individuals, with normal BP proven by the ambulatory blood pressure monitoring...
October 28, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29146157/angiotensin-converting-enzyme-2-activation-ameliorates-pulmonary-endothelial-dysfunction-in-rats-with-pulmonary-arterial-hypertension-through-mediating-phosphorylation-of-endothelial-nitric-oxide-synthase
#3
Gang Li, Han Zhang, Lei Zhao, Yaozhong Zhang, Daole Yan, Yinglong Liu
This study aims to investigate the effect of angiotensin-converting enzyme 2 (ACE2) activation on pulmonary endothelial function in the process of preventing pulmonary arterial hypertension (PAH) in rat models and to explore the underlying mechanisms. Specific pathogen free rats were randomly divided into five groups including control group, PAH group, PAH + Resorcinolnaphthalein (Res) group (ACE2 activation), PAH + Res + MLN4760 group (ACE2 inhibition), and PAH + Res + L-NAME group (endothelial nitric oxide synthase [eNOS] inhibition)...
October 28, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29128603/optimal-blood-pressure-control-after-coronary-events-the-challenge-remains
#4
Elise Sverre, Kari Peersen, Jan Erik Otterstad, Lars Gullestad, Joep Perk, Erik Gjertsen, Torbjørn Moum, Einar Husebye, Toril Dammen, John Munkhaugen
We identified sociodemographic, medical, and psychosocial factors associated with unfavorable blood pressure (BP) control in 1012 patients, hospitalized with myocardial infarction and/or a coronary revascularization procedure. This cross-sectional study collected data from hospital records, a comprehensive self-report questionnaire, clinical examination, and blood samples after 2-36 (mean 17) months follow-up. Forty-six percent had unfavorable BP control (≥140/90 [80 in diabetics] mm Hg) at follow-up. Low socioeconomic status and psychosocial factors did not predict unfavorable BP control...
October 28, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29100861/role-of-angiotensin-ii-type-2-receptor-during-electrophysiological-remodeling-of-left-ventricular-hypertrophic-myocardium-in-spontaneously-hypertensive-rats
#5
Ying Xiao, Wei-Qing Long, Kai-Pan Guan, Ming Long, Gui-Hua Lu, Zhi-Bin Huang
The objective was to investigate the role of angiotensin II type 2 receptor during electrophysiological remodeling of left ventricular hypertrophic myocardium in spontaneously hypertensive rats (SHRs). A total of 36, aged 10 weeks, male SHRs were divided into three groups: control, valsartan, and valsartan + PD123319 groups (n = 12 in each). The systolic blood pressure, left ventricular mass index, ventricular effective refractory period, and ventricular fibrillation threshold (VFT) were also measured after 8 weeks...
October 13, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29089200/albuminuria-and-kidney-function-as-prognostic-marker-of-left-ventricular-mass-among-south-asians-with-hypertension
#6
Liang Feng, Aamir Hameed Khan, Imtiaz Jehan, John Allen, Tazeen H Jafar
We aimed to evaluate the association of albuminuria and estimated glomerular filtration rate (eGFR) at baseline and changes in these parameters with left ventricular mass index (LVMI) at 7 years in adults with hypertension from communities in Pakistan. A nested cohort of 539 hypertensives aged 40 years and older from a community-living population in Karachi, Pakistan, followed up for 7 years in the Control of Blood Pressure and Risk Attenuation trial. Urine spot albumin-to-creatinine ratio (UACR) and serum creatinine-based eGFR were assessed at baseline and 7 years, and echocardiography at 7 years...
October 13, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29030153/potassium-homeostasis-in-health-and-disease-a-scientific-workshop-cosponsored-by-the-national-kidney-foundation-and-the-american-society-of-hypertension
#7
Csaba P Kovesdy, Lawrence J Appel, Morgan E Grams, Lisa Gutekunst, Peter A McCullough, Biff F Palmer, Bertram Pitt, Dominic A Sica, Raymond R Townsend
While much emphasis, and some controversy, centers on recommendations for sodium intake, there has been considerably less interest in recommendations for dietary potassium intake, in both the general population and patients with medical conditions, particularly acute and chronic kidney disease. Physiology literature and cohort studies have noted that the relative balance in sodium and potassium intakes is an important determinant of many of the sodium-related outcomes. A noteworthy characteristic of potassium in clinical medicine is the extreme concern shared by many practitioners when confronted by a patient with hyperkalemia...
October 6, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29102320/body-weight-dependent-relationships-between-alcohol-consumption-and-pulse-pressure-in-middle-aged-japanese-women
#8
Ichiro Wakabayashi
High pulse pressure is a risk factor for cardiovascular disease, and excessive alcohol drinking increases the risk of hypertension. The purpose of this study was to elucidate the relationship between alcohol intake and pulse pressure in women and to determine whether body weight influences their relationship. The subjects were 18,791 Japanese middle-aged women, and they were divided into tertile groups for body weight or three different body mass index (BMI, kg/m(2)) groups (low BMI <22; middle BMI ≥22 and <25; high BMI ≥25)...
October 3, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28882450/the-8-oxo-deoxyguanosine-glycosylase-increases-its-migration-to-mitochondria-in-compensated-cardiac-hypertrophy
#9
Jorge E Vela-Guajardo, Perla Pérez-Treviño, Irais Rivera-Álvarez, Fabio A González-Mondellini, Julio Altamirano, Noemí García
Cardiac hypertrophy is a compensatory mechanism maladapted because it presents an increase in the oxidative stress which could be associated with the development of the heart failure. A mechanism proposed is by mitochondrial DNA (mtDNA) oxidation, which evolved to a vicious cycle because of the synthesis of proteins encoded in the genome is committed. Therefore, the aim of the present work was to evaluate the mtDNA damage and enzyme repairing the 8-oxo-deoxyguanosine glycosylase mitochondrial isoform 1-2a (OGG1-2a) in the early stage of compensated cardiac hypertrophy induced by abdominal aortic constriction (AAC)...
August 24, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28882449/contribution-of-backward-and-forward-wave-pressures-to-age-related-increases-in-aortic-pressure-in-a-community-sample-not-receiving-antihypertensive-therapy
#10
Bryan Hodson, Gavin R Norton, Imraan Ballim, Pinhas Sareli, Angela J Woodiwiss
Reports on the contribution of aortic forward (Pf) and backward (Pb) wave pressures to age-related increases in central aortic pulse pressure (PPc) have been confounded by the use of participants receiving antihypertensive therapy. We assessed the relative contribution of Pf and Pb to age-related increases in PPc (radial applanation tonometry and SphygmoCor software using an assumed triangular wave for wave separation analysis) in 892 community participants not receiving antihypertensive therapy. We validated our results using aortic flow waves (echocardiography) for wave separation analysis in 254 of these participants...
August 24, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28865866/postexercise-hypotension-during-different-water-based-concurrent-training-intrasession-sequences-in%C3%A2-young-women
#11
Stephanie Santana Pinto, Daniel Umpierre, Hector Kerchirne Ferreira, Gabriela Neves Nunes, Rodrigo Ferrari, Cristine Lima Alberton
The purpose of the study was to compare the acute effects of water-based resistance-aerobic (RA) and aerobic-resistance (AR) sequences on systolic blood pressure, diastolic blood pressure (DBP), and mean blood pressure (MBP) in young women. Thirteen active women participated in four sessions: (1) exercises familiarization, (2) aquatic maximal test to determine the heart rate (HR) corresponding to the anaerobic threshold (HRAT), (3) concurrent protocol RA, and (4) concurrent protocol AR. Both protocols were initiated with the blood pressure measurements at rest in supine position...
August 24, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29128028/from-the-editor
#12
EDITORIAL
Daniel Levy
No abstract text is available yet for this article.
November 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29054402/from-the-president-american-society-of-hypertension
#13
EDITORIAL
John D Bisognano, Jan N Basile
No abstract text is available yet for this article.
November 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29032943/assessing-the-validity-of-oscillometric-device-for%C3%A2-blood-pressure-measurement-in-a-large-population-based-epidemiologic-study
#14
Zuo Chen, Xin Wang, Zengwu Wang, Linfeng Zhang, Guang Hao, Ying Dong, Manlu Zhu, Runlin Gao
To evaluate the accuracy of the Omron HBP-1300, an automatic device for blood pressure (BP) measurement, compared with the standard auscultatory method with a mercury sphygmomanometer, we conducted a large population-based survey. From 2012 to 2015, a total of 500,000 participants were randomly selected from the 262 urban cities and rural counties in China, of them BP was measured three times simultaneously with mercury sphygmomanometer and Omron HBP-1300 in 37,816 participants. Bias was estimated as the average of the auscultatory measurements minus the average of the oscillometric measurements, with its corresponding 95% limits of agreement...
November 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29031803/the-burden-and-correlates-of-hypertension-among-chinese-rural-population-in-han-uygur-and-kazak-%C3%A2-a%C3%A2-cross-sectional-study
#15
Yong-Tao Wang, Dilare Adi, Zi-Xiang Yu, Yi-Tong Ma, Yi-Ning Yang, Xiao-Mei Li, Xiang Ma, Fen Liu, Bang-Dang Chen
The present study was conducted to investigate the prevalence, awareness, treatment, control, and associated risk factors of hypertension among rural population in Xinjiang Province in Northwest China. The Cardiovascular Risk Survey study was conducted on a representative sample of the Northwest China adult population. A four-stage stratified cluster random sampling scheme was adopted to recruit representative samples. The data were collected by trained staff. Multivariable logistic regression models were used to identify the associated risk factors...
November 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29031802/extreme-levels-of-ambient-air-pollution-adversely-impact-cardiac-and-central-aortic-hemodynamics-the-aircmd-china-study
#16
Shuo Liu, Robert D Brook, Wei Huang, Zhongjie Fan, Hongbing Xu, Rongshan Wu, Zhichao Sun, Xiaoyi Zhao, Yanping Ruan, Jianhua Yan, Lixian Sun, Ruijuan Liang, Hui Lian, Dongfeng Gu, Sanjay Rajagopalan
Ambient air pollution is an independent risk factor for cardiovascular diseases. However, the underlying mechanisms have yet to be fully elucidated. We performed a panel study on 65 nonsmoking patients with metabolic syndrome, with four repeated clinical visits between 2012 and 2013 in Beijing, China. Cardiac and central aortic hemodynamic parameters were measured by pulse wave analyses as subendocardial viability ratio, ejection duration, and central aortic pressure. We also calculated rate-pressure product parameter and collected peripheral blood for analyses...
November 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28989072/pentoxifylline-treatment-enhances-antihypertensive-activity-of-captopril-through-hemorheological-improvement-in-spontaneously-hypertensive-rats-during-development-of-arterial-hypertension
#17
Mark B Plotnikov, Alexander Y Shamanaev, Oleg I Aliev, Anastasia V Sidekhmenova, Anna M Anishchenko, Alexander M Arkhipov
The rheological properties of blood play a significant role in the onset and progression of arterial hypertension. The aim of our work was to evaluate the effect of the angiotensin-converting enzyme inhibitor captopril (20 mg/kg/d), pentoxifylline (PTX; 100 mg/kg/d), and the combination of captopril + PTX (20 + 100 mg/kg/d) on the hemodynamic and hemorheological parameters in spontaneously hypertensive rats (SHRs) during the development of arterial hypertension. In the group of animals that received captopril, the mean arterial pressure (MAP) was significantly lower by 30% due to a decrease in cardiac output of 23% and in total peripheral resistance (TPR) of 26% compared with the control group, whereas blood viscosity did not change significantly...
November 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28989071/air-pollution-and-arterial-hypertension-a-new-risk-factor-is-in-the-air
#18
REVIEW
Elias Sanidas, Dimitris P Papadopoulos, Harris Grassos, Maria Velliou, Kostas Tsioufis, John Barbetseas, Vasilios Papademetriou
Air pollution is one of the greatest environmental threats and has been implicated for several adverse cardiovascular effects including arterial hypertension (HTN). However, the exact relationship between air pollution exposure and HTN is still unclear. Air contamination provokes oxidative stress, systemic inflammation, and autonomic nervous system imbalance that subsequently induce endothelial dysfunction and vasoconstriction leading to increased blood pressure. The aim of this review was to describe the potential mechanisms by which air pollution contributes to HTN and to summarize the consequences of short- and long-term exposure...
November 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28989070/personal-level-exposure-to-environmental-temperature-is-a-superior-predictor-of-endothelial-dependent-vasodilatation-than-outdoor-ambient-level
#19
Chinedu Ejike, Lu Wang, Mochuan Liu, Wei Wang, Masako Morishita, Robert L Bard, Wei Huang, Jack Harkema, Sanjay Rajagopalan, Robert D Brook
Environmental temperatures influence cardiovascular physiology. However, the majority of time is spent indoors, making outdoor-ambient temperatures inaccurate estimates of true exposures encountered by most individuals. We evaluated in 50 healthy adults the associations between previous 7-day outdoor-ambient (four occasions) and prior 24-hour personal-level (two occasions) environmental temperature exposures with blood pressure, heart rate variability, sleep parameters, and endothelial-dependent vasodilatation (brachial flow-mediated dilatation [FMD]) using generalized estimating equations...
November 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28967550/the-relationship-between-hypertensive-disorders-in-pregnancy-and-placental-maternal-and-fetal-vascular-circulation
#20
Michal Kovo, Jacob Bar, Letizia Schreiber, Marina Shargorodsky
We examined the impact of chronic hypertension (HTN), gestational HTN, and preeclampsia on placental maternal and fetal vascular circulation. Of the 1047 women who gave birth and underwent a placental histopathologic examination between 2007 and 2013 at Wolfson Medical Center, 140 women were included in the present study: 34 women with preeclampsia, 25 women with chronic HTN, 28 women with gestational HTN, and 53 women without hypertensive disorder, matched by age, gravidity, parity, and mode of delivery.Placental lesions related to maternal vascular malperfusion (MVM) differed significantly across groups (P < ...
November 2017: Journal of the American Society of Hypertension: JASH
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