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Journal of the American Society of Hypertension: JASH

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https://www.readbyqxmd.com/read/29960864/cumulative-dose-of-bevacizumab-associates-with-albuminuria-rather-than-podocyturia-in-cancer-patients
#1
Stephanie Lankhorst, Hans J Baelde, Jose A M C Verstijnen, Albert J Ten Tije, Marc H M Thelen, A H Jan Danser, Anton H van den Meiracker, Mariëtte H W Kappers
Angiogenesis inhibition with bevacizumab, a monoclonal antibody against vascular endothelial growth factor A (VEGF-A), is an anticancer treatment associated with hypertension and renal glomerular toxicity referred to as a preeclampsia-like syndrome. In preeclampsia, podocyturia predates proteinuria and clinical features of preeclampsia, and is regarded as a biomarker of ongoing glomerular injury. Using a quantitative polymerase chain reaction of the podocyte-specific molecules nephrin, podocin, and VEGF-A in the urine, we examined whether podocyturia is present in bevacizumab-treated cancer patients, and whether it relates to proteinuria and the cumulative dose of bevacizumab...
June 18, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29958913/postmicturition-syndrome-a-neglected-syndrome-dangerous-for-the-bladder-and-the-heart
#2
Ilaria Jane Romano, Francesco Gentile, Antonio Lippolis
Postmicturition syndrome refers to symptoms caused by overdistension of the bladder or micturition. Bladder paraganglioma is a rare neuroendocrine neoplasm, which arises from the chromaffin tissue of the sympathetic nervous system embedded in the muscle layer of the bladder wall. Clinical presentation of catecholamine-secreting paragangliomas may mimic that of hyperfunctioning adrenal pheochromocytoma. Typical symptoms such as sweating, palpitations, headache, nausea, hypertension, or flushing are due to catecholamine release and are related to micturition or bladder overdistension...
June 18, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29945775/aerobic-training-reduces-blood-pressure-and-waist-circumference-and-increases-hdl-c-in-metabolic-syndrome-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#3
REVIEW
Ítalo Ribeiro Lemes, Bruna Camilo Turi-Lynch, Iván Cavero-Redondo, Stephanie Nogueira Linares, Henrique Luiz Monteiro
The objective of this study is to estimate the effect of aerobic training (AT) on metabolic syndrome (MetS) outcomes. The Medline, EMBASE, SPORTDiscus, The Cochrane Library, and PEDro databases were searched from inception to May 2017. Two independent reviewers selected the studies and assessed their quality and data. The pooled mean differences between intervention groups and the control group were calculated using a random-effect model. Only randomized controlled trials that compared the effect of AT on MetS with a control group were included...
June 18, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29941387/social-capital-and-depression-among-migrant-hypertensive-patients-in-primary-care
#4
Wu Zhu, Haitao Li, Xuejun Wang, Chen Mao
This study was to investigate prevalence of depression among migrant hypertensive patients in primary care and to examine hypertensive patients' social capital and its relationship with the prevalence of depression. An on-site-based cross-sectional study was performed in Shenzhen, China. A total of 830 migrant hypertensive patients completed the survey by using systematic sampling design. A questionnaire including information of depressive symptoms and social capital was administered by face-to-face interview surveys...
June 18, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29929943/corrigendum-to-role-of-angiotensin-ii-type-2-receptor-during-electrophysiological-remodeling-of-left-ventricular-hypertrophic-myocardium-in-spontaneously-hypertensive-rats-journal-of-the-american-society-of-hypertension-january-2018-volume-12-issue-1-pages
#5
Ying Xiao, Wei-Qing Long, Kai-Pan Guan, Ming Long, Gui-Hua Lu, Zhi-Bin Huang
No abstract text is available yet for this article.
June 18, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29937420/the-association-between-antidepressant-use-and-orthostatic-hypotension-in-older-people-a-matched-cohort-study
#6
R Briggs, D Carey, T McNicholas, P Claffey, H Nolan, S P Kennelly, R A Kenny
Orthostatic hypotension (OH) is often reported as a significant potential adverse effect of antidepressant use but the association between phasic blood pressure (BP) and antidepressants has not yet been investigated. This cross-sectional study compares continuously measured phasic BP and prevalence of OH in a cohort of antidepressant users ≥50 years compared with an age- and sex-matched cohort not taking antidepressants. OH was defined as a drop in systolic BP ≥ 20 mm Hg or in diastolic BP ≥ 10 mm Hg at 30 seconds after standing, measured using continuous beat-to-beat finometry...
June 14, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29945776/short-term-exposure-to-dexamethasone-promotes-autonomic-imbalance-to-the-heart-before-hypertension
#7
Francine Duchatsch, Paula B Constantino, Naiara A Herrera, Mayara F Fabrício, Lidieli P Tardelli, Aline M Martuscelli, Thiago J Dionísio, Carlos F Santos, Sandra L Amaral
Hypertension is one of the chronic side effects of dexamethasone (DEX) treatment; however, almost nothing is known about its acute effects. Therefore, the aim of this study was to investigate the possible mechanisms involved in blood pressure control after acute or short-term DEX treatment in adult animals. Eighty Wistar rats were divided into four groups: C1 and C5, for rats treated with saline for 1 or 5 days, respectively; D1 and D5, for rats treated with DEX for 1 or 5 days, respectively (decadron, 1 mg/kg, i...
June 13, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29908726/digital-health-intervention-as-an-adjunct-to-a-workplace-health-program-in-hypertension
#8
Conor Senecal, R Jay Widmer, Matthew P Johnson, Lilach O Lerman, Amir Lerman
BACKGROUND: Hypertension is a common and difficult-to-treat condition; digital health tools may serve as adjuncts to traditional pharmaceutical and lifestyle-based interventions. Using a retrospective observational study we sought to evaluate the effect of a desktop and mobile digital health intervention (DHI) as an adjunct to a workplace health program in those previously diagnosed with hypertension. METHODS: As part of a workplace health program, 3330 patients were identified as previously diagnosed with hypertension...
May 30, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29886153/findings-relevant-to-the-qrs-wave-in-the-resting-electrocardiogram-are-associated-with-circulating-concentrations-of-high-sensitivity-cardiac-troponin-i-in-the-general-population
#9
Tomonori Sugiura, Yasuaki Dohi, Hiroyuki Takase, Satoshi Fujii, Nobuyuki Ohte
Myocardial damage could develop asymptomatically through nonischemic mechanisms such as cardiac overload. This study investigated possible associations between electrocardiogram (ECG) findings relevant to the QRS wave and high-sensitivity cardiac troponin I (hs-cTnI) in the general population. Subjects undergoing their annual health checkup were enrolled in the study (n = 1258). ECG features relevant to the QRS wave that were investigated included PQ interval, QRS voltage (Sokolow-Lyon voltage), QRS duration, product of QRS duration and voltage (Cornell product), corrected QT interval, and QRS axis...
May 18, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29921419/editor-s-page
#10
EDITORIAL
Daniel Levy
No abstract text is available yet for this article.
July 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29861130/renovascular-hypertension-in-small-children-is-it-takayasu-arteritis-or-fibromuscular-dysplasia
#11
EDITORIAL
Kjell Tullus, Derek J Roebuck
No abstract text is available yet for this article.
July 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29804939/ambulatory-hypertension-in-a-pediatric-cohort-of-sickle-cell-disease
#12
Divya G Moodalbail, Bonita Falkner, Scott W Keith, Robert S Mathias, Carlos E Araya, Joshua J Zaritsky, Marie J Stuart
Hypertension is an established risk factor for subsequent cardiovascular and renal disease in children as well as adults. Sickle cell disease (SCD) is a genetic disorder associated with chronic hemolytic anemia with the major manifestation of vaso-occlusive crises. Although this disease entity involves most organ systems causing vascular and pulmonary injury, little is known about blood pressure (BP) levels or prevalence of hypertension in children with SCD. A cross-sectional study was conducted on 56 children with SCD (54 with hemoglobin SS disease; 2 with hemoglobin Sβ0 thalassemia; 29 females)...
July 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29803637/diastolic-blood-pressure-and-risk-profile-in-renal-and-cardiovascular-diseases-results-from-the-sprint-trial
#13
Rita Del Pinto, Davide Pietropaoli, Claudio Ferri
The Systolic Blood Pressure Intervention Trial (SPRINT) trial demonstrated the efficacy and safety of targeting a systolic blood pressure of <120 mmHg compared to <140 mmHg in selected hypertensive patients. Some evidence, however, suggests a J-curve for; diastolic blood pressure (DBP) particularly in subjects with cardiovascular (CV) and chronic kidney disease. We evaluated the risk of events in SPRINT with focus on these subgroups according to DBP. Mean DBP (±standard deviation) throughout follow-up time was calculated for each patient...
July 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29792262/chronic-kidney-disease-as-a-cardiovascular-risk-factor-lessons-from-kidney-donors
#14
REVIEW
Anna M Price, Nicola C Edwards, Manvir K Hayer, William E Moody, Richard P Steeds, Charles J Ferro, Jonathan N Townend
Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease but is often associated with other risks such as diabetes and hypertension and can be both a cause and an effect of cardiovascular disease. Although epidemiologic data of an independent association of reduced glomerular filtration rate with cardiovascular risk are strong, causative mechanisms are unclear. Living kidney donors provide a useful model for assessing the "pure" effects of reduced kidney function on the cardiovascular system...
July 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29784505/the-cardiovascular-health-score-and-the-volume-of-carotid-body-in-computed-tomography-angiography-in-patients-with-arterial-hypertension
#15
Przemysław Jaźwiec, Paweł Gać, Małgorzata Poręba, Małgorzata Sobieszczańska, Grzegorz Mazur, Rafał Poręba
The cardiovascular health (CVH) score constitutes a reliable and measurable indicator of CVH proposed by the American Heart Association (AHA) calculated based on seven fundamental parameters, that is, smoking, body mass index, physical activity, healthy diet score, blood pressure, blood cholesterol, and fasting plasma glucose. The size and activity of carotid body (CB) play an important role in the pathogenesis of the cardiovascular system. The objective of this study was to define the relationship between the AHA CVH score and the volume of CB (VrCB+lCB ) estimated based on computed tomography angiography (CTA) in patients with arterial hypertension...
July 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29784504/balloon-angioplasty-of-renal-artery-stenosis-due-to-takayasu-arteritis-in-a-2-year-old-child
#16
Alimujiang Abudoureyimu, Xingwei He, Jiangtao Yan, Chang Xu, Liru Qiu, Hesong Zeng
The aim of this report is to demonstrate a 2-year-2-month-old child who presented with a history of malignant hypertension. He was made the diagnosis of Takayasu arteritis by laboratory tests and angiography; we initiated a treatment with sequential balloon predilation. The patient's blood pressure improved dramatically, and patency of renal artery was demonstrated with renal arteriography over 8 months after the balloon predilation.
July 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29776759/effect-of-vitamin-d-supplementation-on-blood-pressure-parameters-in-patients-with-vitamin-d-deficiency-a-systematic-review-and-meta-analysis
#17
REVIEW
Liqin Shu, Kun Huang
Evidence suggests that supplementation of vitamin D cannot decrease blood pressure in normal populations. However, in randomized controlled trials (RCTs) with vitamin D deficient participants (defined as baseline serum 25[OH]D levels <30 ng/mL or 50 nmol/L), this effect is inconsistent and under debate. Thus, we performed this systematic review and meta-analysis to evaluate whether vitamin D supplementation could affect blood pressure parameters in vitamin D-deficient subjects. The PubMed, Web of Science, ScienceDirect, and Cochrane library databases were searched...
July 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29678422/significant-interaction-of-hypertension-and-homocysteine-on-neurological-severity-in-first-ever-ischemic-stroke-patients
#18
Ying-Li Fan, Rui Zhan, Yi-Fei Dong, Lei Huang, Xi-Xin Ji, Peng Lu, Jian Liu, Ping Li, Xiao-Shu Cheng
It is not known whether combination of hypertension and high homocysteine (HHcy) impacts on stroke-related neurological severity. Our aim was to determine whether there is an interaction of hypertension and HHcy on neurological severity in first-ever ischemic stroke patients. We analyzed neurological severity among 189 consecutive first-ever ischemic stroke patients with or without hypertension or HHcy. Hypertension (odds ratio [OR]: 8.086, 95% confidence interval [CI]: 3.596-18.181, P < .001) and total homocysteine (OR: 1...
July 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29804916/corrigendum-to-comparison-between-oscillometric-and-intra-arterial-blood-pressure-measurements-in-ill-preterm-and-full-term-neonates-journal-of-american-society-of-hypertension-january-2014-volume-8-issue-1-pages-36-44
#19
https://www.readbyqxmd.com/read/29804915/from-the-editor
#20
EDITORIAL
Daniel Levy
No abstract text is available yet for this article.
June 2018: Journal of the American Society of Hypertension: JASH
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