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Journal of the American Society of Hypertension: JASH

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https://www.readbyqxmd.com/read/28734798/barriers-to-conducting-ambulatory-and-home-blood-pressure-monitoring-during-hypertension-screening-in-the-united-states
#1
Ian M Kronish, Shia Kent, Nathalie Moise, Daichi Shimbo, Monika M Safford, Robert E Kynerd, Ronan O'Beirne, Alexandra Sullivan, Paul Muntner
In 2015, the US Preventive Services Task Force updated their hypertension recommendations to advise that adults with elevated office blood pressure (BP) undergo out-of-office BP measurement to exclude white coat hypertension before diagnosis. Our goal was to determine the most important barriers to primary care providers' ordering ambulatory and home BP monitoring in the United States. We enrolled 63 primary care providers into nominal group panels in which participants iteratively listed and ranked barriers to ambulatory and home BP monitoring...
July 6, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28735679/soluble-endoglin-as-a-prognostic-factor-of-the-claudication-distance-improvement-in-patients-with-peripheral-artery-disease-undergoing-supervised-treadmill-training-program
#2
Rafał Januszek, Piotr Mika, Roman Nowobilski, Witold Nowak, Anna Kusienicka, Damian Klóska, Paweł Maga, Rafał Niżankowski
Conservative therapy after complete revascularization is increasing in popularity in patients with peripheral artery disease (PAD). The aim of the present study was to find determinants of the improvement of walking abilities and endothelial function in patients with PAD undergoing supervised treadmill training program (STTP). The presented study enclosed 66 patients in the mean age 65.4 ± 7.7 years with PAD who underwent a 3-month length STTP. We assessed the effect of following factors on the change of the flow-mediated dilatation value (ΔFMD), maximal walking time (ΔMWT), and pain-free walking time (ΔPFWT)...
June 28, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28689734/global-prevalence-of-hypertension-among-people-living-with-hiv-a-systematic-review-and-meta-analysis
#3
REVIEW
Yunan Xu, Xinguang Chen, Kai Wang
The purpose of this study was to estimate, through meta-analysis, the global prevalence of hypertension among people living with HIV (PLWH). A total of 49 studies published during 2011-2016 with 63,554 participants were included in analysis. These studies were conducted in America (25), Europe (13), Africa (10), and Asia (1) with data collected during 1996-2014. Prevalence of hypertension and confidence interval was estimated and stratified by participants' age, antiretroviral therapy (ART), and calendar-years using random effects modeling...
June 21, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28676236/white-coat-effect-in-hypertensive-patients-the-role-of-hospital-environment-or-physician-presence
#4
Xi-Xing Wang, Wei Shuai, Qiang Peng, Ju-Xiang Li, Ping Li, Xiao-Shu Cheng, Hai Su
This study was to evaluate the role of hospital environment or physician presence for white coat effect (WCE) in hypertensive patients. At first, 54 hypertensive outpatients diagnosed on office blood pressure (OBP) were included for 2-week placebo run in. During the second week of the run in period, home BP was measured using electronic BP monitors for 5-7 days. Finally, 26 sustained hypertensive patients with home systolic BP/diastolic BP over 135/85 (but <180/110) mm Hg were enrolled for 8-week treatment of nifedipine controlled-release tablet...
June 21, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28666705/evaluation-of-high-blood-pressure-and-obesity-among-us-coal-miners-participating-in-the-enhanced-coal-workers-health-surveillance-program
#5
Megan Lauren Casey, Kathleen B Fedan, Nicole Edwards, David J Blackley, Cara N Halldin, Anita L Wolfe, Anthony Scott Laney
Since 2005, the Enhanced Coal Workers' Health Surveillance Program (ECWHSP) has offered respiratory examinations to coal miners in a mobile examination unit. As little is known about the cardiovascular health of coal miners, we describe the prevalence of high blood pressure (BP) and obesity among ECWHSP participants. During 2015, 1402 ECWHSP health examinations were performed. The prevalence of BP consistent with hypertension (systolic BP ≥ 140 mm Hg or diastolic BP ≥ 90 mm Hg), prehypertension (systolic BP 120-139 mm Hg or diastolic BP 80-89 mm Hg), and hypertensive crisis (systolic BP ≥ 180 mm Hg or diastolic BP ≥ 110 mm Hg) were calculated and compared with the US adult population using standardized morbidity ratios (SMRs)...
June 20, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28668444/the-effect-of-circadian-blood-pressure-pattern-on-presence-of-fragmented-qrs-complexes-in-hypertensive-subjects
#6
Mehmet Eyuboglu, Yavuz Karabag, Suleyman Karakoyun, Bahri Akdeniz
The association of deteriorated circadian blood pressure (BP) variability with presence of fragmented QRS (fQRS) on electrocardiography (ECG) is not clear. The present study aims to evaluate the relationship of BP patterns with presence of fQRS on ECG. A total of 338 consecutive newly diagnosed and never treated hypertensive patients who are without left ventricular hypertrophy and underwent 24-hour ambulatory BP monitoring were enrolled. Patients were classified as dippers, nondippers, and reverse dippers according to ambulatory BP monitoring results...
June 12, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28666704/systemic-and-tissue-specific-effects-of-aliskiren-on-the-raas-and-carbohydrate-lipid-metabolism-in-obese-patients-with-hypertension
#7
Stefan Engeli, Marcus May, Juerg Nussberger, A H Jan Danser, William P Dole, Margaret F Prescott, Marion Dahlke, Sylvie Stitah, Parasar Pal, Michael Boschmann, Jens Jordan
Aliskiren penetrates adipose and skeletal muscle in hypertensive patients with abdominal obesity and reduces renin-angiotensin-aldosterone system activity. After discontinuation, blood pressure-lowering effects are observed possibly through drug-tissue binding. We performed microdialysis evaluation of adipose tissue and skeletal muscle before and during an insulin-modified frequently sampled intravenous glucose tolerance test (IM-FSIGT). Aliskiren 300 mg (n = 8) or amlodipine 5 mg (n = 8) once daily were administered during a 12-week randomized treatment period...
June 12, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28666706/prevalence-awareness-treatment-and-control-of-hypertension-among-very-elderly-chinese-results-of-a-community-based-study
#8
Gang Huang, Jun-Bo Xu, Ting-Jie Zhang, Qiu Li, Xiao-Li Nie, Ya Liu, Shun-Rong Peng, Jian-Kang Liu, Xing-Tang Liu, Xiao-Ling Kang
The epidemiologic distribution of hypertension among very elderly Chinese is still not clear. This study aimed to investigate the prevalence, awareness, treatment, and control rate of hypertension among very elderly in Chengdu. From May 2013 to May 2015, a total of 1056 participants from 20 residential communities were sampled. Standard face-to-face interviews, physical examinations, and biochemical analysis were undertaken. Participants had a mean age of 83.6 ± 3.4 years (range: 80-100), and 49.8% were men...
June 8, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28642065/severe-and-resistant-hypertension-in-an-older-woman-with-claudication
#9
Puneet Gupta, Robert Hagberg, Electra Kaloudis, Anika Lucas, Parth Shah, William B White
Coarctation of the aorta is an uncommon cause of treatment-resistant hypertension in adults. It is typically detected and treated in infancy or childhood with surgical or endovascular procedures. Most cases of recurrence of coarctation after repair occur in childhood or early adulthood; recurrence in older persons (>70 years) has rarely been reported. A 73-year-old woman was referred to us for the management of treatment-resistant hypertension accompanied by symptoms of claudication and headaches, which had resulted in multiple emergency room visits...
June 1, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28624170/predictors-of-visit-to-visit-blood-pressure-variability-in-patients-with-hypertension-an-analysis-of-trials-with-an-amlodipine-treatment-arm
#10
Ji-Guang Wang, Duo Zhou, Barrett W Jeffers
We conducted a post hoc analysis of blood pressure (BP) data from long-term antihypertensive trials to identify predictors of visit-to-visit BP variability (BPV). BPV was defined as the within-subject coefficient of variation in systolic BP from week 12 onward. BP data from the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm, Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial, Comparison of Amlodipine Versus Enalapril to Limit Occurrences of Thrombosis, NY92011, and R-0510 trials were pooled and dichotomized into top 25th and bottom 75th percentiles because of positive skew...
May 29, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28652105/pharmacokinetic-pharmacodynamic-and-antihypertensive-effects-of-the-neprilysin-inhibitor-lcz-696-sacubitril-valsartan
#11
REVIEW
Steven G Chrysant
LCZ-696, sacubitril/valsartan, is a dual-acting molecule consisting of the angiotensin II (Ang II) receptor blocker valsartan and the neprilysin (neutral endopeptidase) inhibitor AHU-377 with significant beneficial effects in patients with hypertension and heart failure (HF). Several recent studies have demonstrated a higher effectiveness of LCZ-696 compared to valsartan in the treatment of hypertension and HF. The rationale for the development and the Food and Drug Administration approval of LCZ-696 was based on the concept of an additive effect of the Ang II receptor blocker valsartan and the neutral endopeptidase (neprilysin) inhibitor AHU-377 for the treatment of hypertension and HF...
May 25, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28624171/race-and-sex-differences-in-ambulatory-blood-pressure-measures-among-hiv-adults
#12
Shia T Kent, Joseph E Schwartz, Daichi Shimbo, Edgar T Overton, Greer A Burkholder, Suzanne Oparil, Michael J Mugavero, Paul Muntner
Ambulatory blood pressure monitoring (ABPM) can identify phenotypes that cannot be measured in the clinic. Determining race and sex disparities in ABPM measures among HIV+ individuals may improve strategies to diagnose and treat hypertension in this high-risk population. We compared ABPM measures between 24 African-American and 25 white HIV+ adults (36 men and 13 women). Awake systolic blood pressure (SBP) and diastolic blood pressure (DBP) were similar in African-Americans and whites. After multivariable adjustment, sleep SBP and DBP were 9...
May 25, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28619598/incremental-prognostic-value-of-a-complex-left-ventricular-remodeling-classification-in-asymptomatic-for-heart-failure-hypertensive-patients
#13
Iacopo Fabiani, Nicola Riccardo Pugliese, Salvatore La Carrubba, Lorenzo Conte, Francesco Antonini-Canterin, Paolo Colonna, Frank Benedetto, Enrico Calogero, Valentina Barletta, Scipione Carerj, Simona Buralli, Stefano Taddei, Maria Francesca Romano, Vitantonio Di Bello
We evaluated the prognostic impact of a complex remodeling classification (CRC) in asymptomatic patients with arterial hypertension (AH). We retrospectively included 749 hypertensive patients (female 325, 43.4% age 62 ± 11.3 years) in Stages A and B of heart failure. CRC was evaluated including indexed left ventricular mass, end-diastolic volume, and relative wall thickness. After 45-month follow-up, we considered a composite endpoint: total mortality, myocardial infarction, myocardial revascularization, cerebrovascular events, and acute pulmonary edema...
May 25, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28602674/serum-metabolomic-response-to-exercise-training-in-spontaneously-hypertensive-rats
#14
Xiangyang Liu, Yanjun Wang, Rui Gao, Ying Xing, Xiaomiao Li, Zhengjun Wang
Chronic aerobic exercise training exhibits blood pressure protective effects, but the mechanism in metabolic level remains largely unclear. This study aims to investigate the effect of exercise training from serum metabolic profiles on the development of hypertension in spontaneously hypertensive rats (SHRs). Exercise training was performed, and the serum metabolites were measured by integrating gas chromatography-mass spectrometer and correlation-based network analysis. After a period of 6 weeks of chronic aerobic exercise training, systolic blood pressure was significant lower in the exercise training group (SHR + EX) rats than the control group (SHR)...
May 20, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28551091/prevalence-awareness-treatment-and-control-of-hypertension-in-older-people-in-central-africa-the-epidemca-study
#15
Sophie Pilleron, Victor Aboyans, Pascal Mbelesso, Bébène Ndamba-Bandzouzi, Ileana Desormais, Philippe Lacroix, Pierre-Marie Preux, Maëlenn Guerchet
Hypertension represents a major global health burden. While older individuals of African descent are at higher risk of hypertension in western countries, epidemiologic data on hypertension in older native Africans are scarce. We assessed the prevalence and the level of awareness and control of hypertension among older adults in Central Africa. A total of 1990 individuals aged 65 years and older from the Republic of Congo and the Central African Republic participated into a cross-sectional population-based survey...
May 9, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28551092/speckle-tracking-echocardiography-and-tissue-doppler-imaging-reveal-beneficial-effect-of-pharmacotherapy-in-hypertensives-with-asymptomatic-left-ventricular-dysfunction
#16
Beata Uziębło-Życzkowska, Paweł Krzesiński, Grzegorz Gielerak, Andrzej Skrobowski
Global longitudinal strain (GLS), assessed by speckle tracking echocardiography, is a sensitive marker of myocardial systolic function and an independent predictor of cardiovascular outcomes. The aim of this study was to investigate the effect of hypotensive treatment on GLS and evaluate the relation between change in GLS and left ventricular (LV) diastolic function. In a group of 125 hypertensive subjects, without any symptoms of heart failure, the detailed echocardiographic assessment of LV systolic and diastolic function was performed before and after 12 months of hypotensive treatment...
May 8, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28545768/elastin-microfibril-interface-located-protein-1-transforming-growth-factor-beta-and-implications-on-cardiovascular-complications
#17
REVIEW
Amy Randell, Noriko Daneshtalab
Elastin microfibril interface-located protein 1 (EMILIN1), a glycoprotein, is associated with elastin in the extracellular matrix (ECM) of arteries, lymph vasculature, and other tissues. EMILIN1 particularly has a niche role in elastin fiber biogenesis (elastogenesis) by aiding with the fusion of elastin fibers, rendering them more ordered. In addition to elastogenesis, EMILIN1 has been shown to have roles in maintenance of vascular cell morphology, smooth muscle cell adhesion to elastic fibers, and transforming growth factor (TGFβ) regulation, by inhibiting TGFβ activation via blocking the proteolytic production of the latency-associated peptide/active TGFβ complex...
May 3, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28645731/aortic-backward-waves-rather-than-stiffness-account-for-independent-associations-between-pulse-pressure-amplification-and-left-ventricular-mass-in-a-young-to-middle-aged-sample
#18
Moekanyi J Sibiya, Gavin R Norton, Hendrik L Booysen, Grace Tade, Carlos D Libhaber, Imraan Ballim, Pinhas Sareli, Angela J Woodiwiss
A decreased aortic-to-brachial pulse pressure (PP) amplification, which is independently associated with cardiovascular outcomes, may index several aortic functional changes. However, that aortic functional change most likely to account for this effect is uncertain. In 706 randomly selected community participants of African ancestry with a mean age of 44.4 ± 18.2 years, we assessed aortic function using radial applanation tonometry and SphygmoCor software (including forward [Pf] and backward [Pb] wave separation analysis assuming a triangular flow waveform) and left ventricular mass index (LVMI) (echocardiography)...
June 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28645730/the-relation-of-digital-vascular-function-to-cardiovascular-risk-factors-in-african-americans-using-digital-tonometry-the-jackson-heart-study
#19
Eric E McClendon, Solomon K Musani, Tandaw E Samdarshi, Sushant Khaire, Donny Stokes, Naomi M Hamburg, Koby Sheffy, Gary F Mitchell, Herman R Taylor, Emelia J Benjamin, Ervin R Fox
Digital vascular tone and function, as measured by peripheral arterial tonometry (PAT), are associated with cardiovascular risk and events in non-Hispanic whites. There are limited data on relations between PAT and cardiovascular risk in African-Americans. PAT was performed on a subset of Jackson Heart Study participants using a fingertip tonometry device. Resting digital vascular tone was assessed as baseline pulse amplitude. Hyperemic vascular response to 5 minutes of ischemia was expressed as the PAT ratio (hyperemic/baseline amplitude ratio)...
June 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28645729/the-dietary-approaches-to-stop-hypertension-dash-diet-promise-unmet
#20
EDITORIAL
Michael J Bloch
No abstract text is available yet for this article.
June 2017: Journal of the American Society of Hypertension: JASH
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