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Clinical Schizophrenia & related Psychoses

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https://www.readbyqxmd.com/read/29164931/the-clinical-impact-of-neuroimaging-in-first-episode-psychosis
#1
Laura J Pientka, S Charles Schulz, Kelvin O Lim, Suzanne G Jasberg
No abstract text is available yet for this article.
November 22, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/29164930/relapse-risk-assessment-for-schizophrenia-patients-rasp-a-new-self-report-screening-tool
#2
Dawn Velligan, William Carpenter, Heidi C Waters, Nicole M Gerlanc, Susan N Legacy, Charles Ruetsch
OBJECTIVES: The Relapse Assessment for Schizophrenia Patients (RASP) was developed as a 6- question self-report screener that measures indicators of Increased Anxiety and Social Isolation to assess patient stability and predict imminent relapse. This paper describes the development and psychometric characteristics of the RASP. METHODS: The RASP and Positive and Negative Syndrome Scale (PANSS) were administered to patients with schizophrenia (N=166) 3 separate times...
November 22, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/29164929/psychosis-as-a-sequelae-of-paraneoplastic-syndrome-in-small-cell-lung-carcinoma-a-psycho-neuroendocrine-interface
#3
Christiana M Wilkins, Victoria L Johnson, Rachel E Fargason, Badari Birur
In 2013 more than 150,000 Americans died from all types of lung cancer. Small cell lung cancer (SCLC) represents about 13% of all lung cancers and is notoriously associated with paraneoplastic syndromes (PNS). Here we present an interesting case of psychosis associated with one such PNS-- ectopic Cushing syndrome of SCLC. A 56 year old African-American male with no prior psychiatric history who was diagnosed with SCLC two months prior, presented to the ER for treatment of a right arm laceration he sustained while fighting off attackers, with high concern these individuals may have been part of hallucinatory experiences and well-systematized persecutory delusions regarding his wife...
November 22, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/29164928/clozapine-diabetes-mellitus-cardiovascular-risk-and-mortality-results-of-a-21-year-naturalistic-study-in-patients-with-schizophrenia-and-schizoaffective-disorder
#4
Katlyn L Nemani, M Claire Greene, Melissa Ulloa, Brenda Vincenzi, Paul M Copeland, Sulaiman Al-Khadari, David C Henderson
The goal of this 21-year naturalistic study of clozapine treated patients was to examine the cardiovascular risk factors following clozapine initiation and resultant mortality estimates from cardiovascular disease. Data was collected from medical records of clozapine treated patients with schizophrenia or schizoaffective disorder from January 1992 to February 2012. Demographics, clozapine dosage and laboratory results were extracted at 12-month intervals. At clozapine initiation, the mean age of 96 patients was 36...
November 22, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/29164927/a-case-of-a-patient-with-residual-symptoms-of-schizophrenia-who-relapsed-following-treatment-with-the-topical-corticosteroid-clobetasol-a-review-of-its-risk-of-systemic-absorption-and-possibility-of-exacerbating-psychosis
#5
David R Spiegel, Umer Arsani, Stephanie Le
Almost fifty percent of patients with schizophrenia experience some type of dermatitis. The standard treatment for dermatitis is a topical corticosteroid. Despite their demonstrated effectiveness, topical corticosteroids are associated with various side effects that may limit their use. These include generalized adverse effects from systemic absorption, such as suppression of the hypothalamic-pituitary-adrenal axis. While dose-related, oral corticosteroid-induced psychiatric symptoms, such as psychosis, are well documented, the literature is devoid of cases of topical corticosteroids precipitating psychosis...
November 22, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777034/chronic-schizophrenia-later-diagnosed-with-anti-nmda-receptor-encephalitis-case-report-and-review-of-the-literature
#6
Meghan A Conroy, Thomas Finch, Tomer T Levin, Alexander E Merkler, Joseph Safdieh, Susan Samuels, Janna S Gordon Elliott
No abstract text is available yet for this article.
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777033/pulmonary-embolism-during-stuporous-episodes-of-catatonia-was-found-to-be-the-most-frequent-cause-of-preventable-death-according-to-a-state-mortality-review-6-deaths-in-15-years
#7
Rocio Puentes, Allen Brenzel, Jose de Leon
Case reports have indicated that pulmonary embolism (PE) can be associated with deaths during episodes of catatonia. A 15-year death registry in Kentucky state psychiatric hospitals was reviewed for deaths during episodes of catatonia. From 2002 to May of 2016, reports of 96 deaths at these state psychiatric hospitals were found and reviewed by the state mortality committee. The charts of the identified catatonic patients were thoroughly reviewed. All 6 deaths occurred during episodes of what Fink and Taylor would call retarded catatonia and Ungvari would call acute stuporous catatonia...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777032/suicidal-ideation-in-an-egyptian-sample-of-hospitalized-patients-with-acute-psychosis
#8
Maha Ftouh, El-Sayed Gad, Mohammad A Seleem, Sameh Saada, Ahmed A Mubarak
BACKGROUND: Suicide mortality is 12 times higher in psychotic patients compared to the general population. Identifying characteristic of suicidal patients among this group might help in preventing such behavior. AIMS: To assess the predictors of suicidal risk in patients hospitalized due to acute psychosis. METHODS: One hundred and fifty patients (age 18 - 60 years) admitted with acute psychotic features were recruited. Patients were evaluated clinically by The Arabic version of Mini International Neuropsychiatric Interview (M...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777031/the-impact-of-stigma-on-subjective-well-being-in-people-with-mental-disorders
#9
Clara I Morgades-Bamba, María José Fuster-Ruizdeapodaca, Fernando Molero
RATIONALE: People diagnosed with a mental disorder are highly discriminated against, and when they internalize the social stigma they suffer severe consequences which have been associated with greater symptomatology and reduced recovery. This research was carried out in order to develop a predictive model about how discrimination contributes to subjective well-being (positive and negative affects experienced) by means of internalization of stigma (alienation, stereotype endorsement and social withdrawal) and deterioration of positive self-concept (self-esteem and self-efficacy)...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777030/a-rare-presentation-of-auto-emasculation-in-a-patient-with-schizoaffective-disorder-management-with-clozapine
#10
Badari Birur, Nina V Kraguljac
No abstract text is available yet for this article.
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777029/characterizing-smartphone-engagement-for-schizophrenia-results-of-a-naturalist-mobile-health-study
#11
John Torous, Patrick Staples, Linda Slaters, Jared Adams, Luis Sandoval, J P Onnela, Matcheri Keshavan
INTRODUCTION: Despite growing interest in smartphone apps for schizophrenia, little is known about how these apps are utilized in the real world. Understanding how app users are engaging with these tools outside of the confines of traditional clinical studies offers an important information on who is most likely to use apps and what type of data they are willing to share. METHODS: The Schizophrenia and Related Disorders Alliance of America, in partnership with Self Care Catalyst, has created a smartphone app for schizophrenia that is free and publically available on both Apple iTunes and Google Android Play stores...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777028/preliminary-validation-of-a-clinical-staging-model-in-schizophrenia-and-related-disorders
#12
Amy Tedja, Eva Velthorst, Mirjam van Tricht, Lieuwe de Haan
Clinical staging for schizophrenia and related disorders might provide an ideal means to overcome some limitations of the current diagnostic system and to facilitate early intervention. This study aims to retrospectively explore 1) the validity of a staging model 2) the stability of staging over time, and 3) the clinical factors associated with transition to more chronic stages. Data were derived from the Genetic Risk and Outcome of Psychosis study, a large cohort study of patients with a schizophrenia spectrum disorder...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777027/exercise-associated-extrapyramidal-symptoms-during-treatment-with-long-acting-injectable-antipsychotic-medications-a-case-report
#13
David D Kim, Donna J Lang, Darren E R Warburton, Alasdair M Barr, Randall F White, William G Honer, Ric M Procyshyn
Antipsychotic medications can effectively treat psychotic symptoms in individuals with schizophrenia. However, side effects including cardiovascular and extrapyramidal symptoms are often inevitable. Exercise has proven effective in ameliorating cardiometabolic abnormalities in individuals with schizophrenia. In addition, exercise has consistently been an effective intervention for improving the symptoms associated with schizophrenia. We report here two cases in which individuals with schizoaffective disorder treated with a long-acting injectable antipsychotic medication displayed worsening of extrapyramidal symptoms over the course of a 12-week exercise program...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/29035102/clinical-news
#14
Peter F Buckley
No abstract text is available yet for this article.
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/25711508/disorganized-symptoms-predicted-worse-functioning-outcome-in-schizophrenia-patients-with-established-illness
#15
Bruno Bertolucci Ortiz, Ary Gadelha, Cinthia Hiroko Higuchi, Cristiano Noto, Daiane Medeiros, José Cássio do Nascimento Pitta, Gerardo Maria de Araújo Filho, Jaime Eduardo Cecílio Hallak, Rodrigo Affonseca Bressan
Most patients with schizophrenia will have subsequent relapses of the disorder, with continuous impairments in functioning. However, evidence is lacking on how symptoms influence functioning at different phases of the disease. This study aims to investigate the relationship between symptom dimensions and functioning at different phases: acute exacerbation, nonremission and remission. METHODS: Patients with schizophrenia were grouped into acutely ill (n=89), not remitted (n=89), and remitted (n=69)...
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/25367167/the-relative-importance-of-family-history-gender-mode-of-onset-and-age-at-onsetin-predicting-clinical-features-of-first-episode-psychotic-disorders
#16
Michael T Compton, Chantal Berez, Elaine F Walker
OBJECTIVE: Family history of psychosis, gender, mode of onset, and age at onset are considered prognostic factors important to clinicians evaluating first-episode psychosis; yet, clinicians have little guidance as to how these four factors differentially predict early-course substance abuse, symptomatology, and functioning. We conducted a "head-to-head comparison" of these four factors regarding their associations with key clinical features at initial hospitalization. We also assessed potential interactions between gender and family history with regard to age at onset of psychosis and symptom severity...
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/25367166/can-transcranial-direct-current-stimulation-improve-cognitive-functioning-in-adults-with-schizophrenia
#17
David J Schretlen, Joseph J van Steenburgh, Mark Varvaris, Tracy D Vannorsdall, Megan A Andrejczuk, Barry Gordon
Cognitive impairment is nearly ubiquitous in schizophrenia. First-degree relatives of persons with schizophrenia often show similar but milder deficits. Current methods for the treatment of schizophrenia are often ineffective in cognitive remediation. Since transcranial direct current stimulation (tDCS) can enhance cognitive functioning in healthy adults, it might provide a viable option to enhance cognition in schizophrenia. We sought to explore whether tDCS can be tolerated by persons with schizophrenia and potentially improve their cognitive functioning...
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/25367163/the-long-term-effects-of-cellular-telephone-delivered-telephone-intervention-problem-solving-tips-for-schizophrenia-spectrum-disorders-ssds-rationale-and-design
#18
Lora H Beebe, Kathlene Smith, Chad Phillips, Dawn Velligan, Abbas Tavakoli
No abstract text is available yet for this article.
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/24496045/adherence-to-diabetes-medication-in-individuals-with-schizophrenia-a-systematic-review-of-rates-and-determinants-of-adherence
#19
REVIEW
Paul Gorczynski, Hiren Patel, Rohan Ganguli
INTRODUCTION: Despite the importance of medication adherence for the effective treatment of type II diabetes mellitus (T2DM), little research has examined adherence with diabetes medication treatment in schizophrenia. The purpose of this systematic review was to: 1) evaluate rates of adherence and determinants of adherence with medication for T2DM in individuals with schizophrenia; and, where possible, 2) examine the relationship between medication adherence and glycemic control. METHODS: Studies were included if they presented information on dosing regimens and adherence or compliance rates for T2DM and included samples where at least 50% of the participants were individuals with schizophrenia...
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/27996318/brain-natriuretic-peptide-as-a-biomarker-of-asymptomatic-clozapine-related-heart-dysfunction-a-criterion-for-a-more-cautious-administration
#20
Vincenzo Prisco, Petrosino Monica, Germano Fiore, Annamaria Tridente, Antonietta La Rocca, Francesco Catapano, Michele Fabrazzo
Clozapine-related pericarditis is a rare side effect of the drug. We reported the clinical cases of two women, aged 22 and 28 years, affected by schizophrenia with pericarditis symptoms related to clozapine treatment of 200 mg/day. Clozapine was discontinued in both patients, resulting in normalization of the ECG changes, and echocardiography confirmed the progressive disappearance of the pericardial effusion. Interestingly, while inflammatory indices and pro-brain natriuretic peptide (pro-BNP) plasma levels were high in both patients, only one of them showed tachycardia, subjective chest pain, shortness of breath and dyspnea, with a clinical symptomatology suggesting a cardiac involvement...
December 20, 2016: Clinical Schizophrenia & related Psychoses
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