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Clinical Schizophrenia & related Psychoses

journal
https://www.readbyqxmd.com/read/28777034/chronic-schizophrenia-later-diagnosed-with-anti-nmda-receptor-encephalitis-case-report-and-review-of-the-literature
#1
Meghan A Conroy, Thomas Finch, Tomer T Levin, Alexander E Merkler, Joseph Safdieh, Susan Samuels, Janna S Gordon Elliott
No abstract text is available yet for this article.
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777033/pulmonary-embolism-during-stuporous-episodes-of-catatonia-was-found-to-be-the-most-frequent-cause-of-preventable-death-according-to-a-state-mortality-review-6-deaths-in-15-years
#2
Rocio Puentes, Allen Brenzel, Jose de Leon
Case reports have indicated that pulmonary embolism (PE) can be associated with deaths during episodes of catatonia. A 15-year death registry in Kentucky state psychiatric hospitals was reviewed for deaths during episodes of catatonia. From 2002 to May of 2016, reports of 96 deaths at these state psychiatric hospitals were found and reviewed by the state mortality committee. The charts of the identified catatonic patients were thoroughly reviewed. All 6 deaths occurred during episodes of what Fink and Taylor would call retarded catatonia and Ungvari would call acute stuporous catatonia...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777032/suicidal-ideation-in-an-egyptian-sample-of-hospitalized-patients-with-acute-psychosis
#3
Maha Ftouh, El-Sayed Gad, Mohammad A Seleem, Sameh Saada, Ahmed A Mubarak
BACKGROUND: Suicide mortality is 12 times higher in psychotic patients compared to the general population. Identifying characteristic of suicidal patients among this group might help in preventing such behavior. AIMS: To assess the predictors of suicidal risk in patients hospitalized due to acute psychosis. METHODS: One hundred and fifty patients (age 18 - 60 years) admitted with acute psychotic features were recruited. Patients were evaluated clinically by The Arabic version of Mini International Neuropsychiatric Interview (M...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777031/the-impact-of-stigma-on-subjective-well-being-in-people-with-mental-disorders
#4
Clara I Morgades-Bamba, María José Fuster-Ruizdeapodaca, Fernando Molero
RATIONALE: People diagnosed with a mental disorder are highly discriminated against, and when they internalize the social stigma they suffer severe consequences which have been associated with greater symptomatology and reduced recovery. This research was carried out in order to develop a predictive model about how discrimination contributes to subjective well-being (positive and negative affects experienced) by means of internalization of stigma (alienation, stereotype endorsement and social withdrawal) and deterioration of positive self-concept (self-esteem and self-efficacy)...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777030/a-rare-presentation-of-auto-emasculation-in-a-patient-with-schizoaffective-disorder-management-with-clozapine
#5
Badari Birur, Nina V Kraguljac
No abstract text is available yet for this article.
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777029/characterizing-smartphone-engagement-for-schizophrenia-results-of-a-naturalist-mobile-health-study
#6
John Torous, Patrick Staples, Linda Slaters, Jared Adams, Luis Sandoval, J P Onnela, Matcheri Keshavan
INTRODUCTION: Despite growing interest in smartphone apps for schizophrenia, little is known about how these apps are utilized in the real world. Understanding how app users are engaging with these tools outside of the confines of traditional clinical studies offers an important information on who is most likely to use apps and what type of data they are willing to share. METHODS: The Schizophrenia and Related Disorders Alliance of America, in partnership with Self Care Catalyst, has created a smartphone app for schizophrenia that is free and publically available on both Apple iTunes and Google Android Play stores...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777028/preliminary-validation-of-a-clinical-staging-model-in-schizophrenia-and-related-disorders
#7
Amy Tedja, Eva Velthorst, Mirjam van Tricht, Lieuwe de Haan
Clinical staging for schizophrenia and related disorders might provide an ideal means to overcome some limitations of the current diagnostic system and to facilitate early intervention. This study aims to retrospectively explore 1) the validity of a staging model 2) the stability of staging over time, and 3) the clinical factors associated with transition to more chronic stages. Data were derived from the Genetic Risk and Outcome of Psychosis study, a large cohort study of patients with a schizophrenia spectrum disorder...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28777027/exercise-associated-extrapyramidal-symptoms-during-treatment-with-long-acting-injectable-antipsychotic-medications-a-case-report
#8
David D Kim, Donna J Lang, Darren E R Warburton, Alasdair M Barr, Randall F White, William G Honer, Ric M Procyshyn
Antipsychotic medications can effectively treat psychotic symptoms in individuals with schizophrenia. However, side effects including cardiovascular and extrapyramidal symptoms are often inevitable. Exercise has proven effective in ameliorating cardiometabolic abnormalities in individuals with schizophrenia. In addition, exercise has consistently been an effective intervention for improving the symptoms associated with schizophrenia. We report here two cases in which individuals with schizoaffective disorder treated with a long-acting injectable antipsychotic medication displayed worsening of extrapyramidal symptoms over the course of a 12-week exercise program...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28742396/valbenazine-for-tardive-dyskinesia
#9
Oliver Freudenreich, Gary Remington
Tardive dyskinesia (TD) remains a clinical concern for any patient who receives an antipsychotic. While the overall risk of developing TD is lower with newer antipsychotics compared to older agents, a significant number of patients who require long-term treatment will develop TD. Recently, valbenazine (brand name Ingrezza) became the first drug to be approved by the FDA specifically for the treatment of TD. In this New Drug Review, we summarize the basic pharmacology and clinical trial results for valbenazine...
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28742395/highlights-from-the-biennial-international-congress-on-schizophrenia-research-icosr-march-24-march-28-2017
#10
Hakon Heimer
The 2017 International Congress on Schizophrenia Research, held in San Diego, California (March 24-28, 2017), attracted over 900 attendees from 34 countries. With the gracious assistance of Congress president James Meador-Woodruff, we bring you the following reports on the prospects for new drugs to treat schizophrenia.
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28742394/assessment-of-proteomic-measures-across-serious-psychiatric-illness
#11
S Charles Schulz, Shauna Overgaard, David J Bond, Rajesh Kaldate
The diagnoses of serious psychiatric illnesses, such as schizophrenia, schizoaffective disorder, and bipolar disorder, rely on the subjective recall and interpretation of often overlapping symptoms, and are not based on the objective pathophysiology of the illnesses. The subjectivity of symptom reporting and interpretation contributes to the delay of accurate diagnoses and limits effective treatment of these illnesses. Proteomics, the study of the types and quantities of proteins an organism produces, may offer an objective biological approach to psychiatric diagnosis...
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28742393/clinical-news
#12
Peter F Buckley
No abstract text is available yet for this article.
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/24496045/adherence-to-diabetes-medication-in-individuals-with-schizophrenia-a-systematic-review-of-rates-and-determinants-of-adherence
#13
REVIEW
Paul Gorczynski, Hiren Patel, Rohan Ganguli
INTRODUCTION: Despite the importance of medication adherence for the effective treatment of type II diabetes mellitus (T2DM), little research has examined adherence with diabetes medication treatment in schizophrenia. The purpose of this systematic review was to: 1) evaluate rates of adherence and determinants of adherence with medication for T2DM in individuals with schizophrenia; and, where possible, 2) examine the relationship between medication adherence and glycemic control. METHODS: Studies were included if they presented information on dosing regimens and adherence or compliance rates for T2DM and included samples where at least 50% of the participants were individuals with schizophrenia...
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/27996318/brain-natriuretic-peptide-as-a-biomarker-of-asymptomatic-clozapine-related-heart-dysfunction-a-criterion-for-a-more-cautious-administration
#14
Vincenzo Prisco, Petrosino Monica, Germano Fiore, Annamaria Tridente, Antonietta La Rocca, Francesco Catapano, Michele Fabrazzo
Clozapine-related pericarditis is a rare side effect of the drug. We reported the clinical cases of two women, aged 22 and 28 years, affected by schizophrenia with pericarditis symptoms related to clozapine treatment of 200 mg/day. Clozapine was discontinued in both patients, resulting in normalization of the ECG changes, and echocardiography confirmed the progressive disappearance of the pericardial effusion. Interestingly, while inflammatory indices and pro-brain natriuretic peptide (pro-BNP) plasma levels were high in both patients, only one of them showed tachycardia, subjective chest pain, shortness of breath and dyspnea, with a clinical symptomatology suggesting a cardiac involvement...
December 20, 2016: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/27996317/cardiac-arrest-with-clozapine-and-olanzapine-revealing-long-qt-syndrome
#15
Edward Woloszyn, Nishant Whig, Eileen Trigoboff, Jeffery J Grace
The authors describe a rare case of "concealed" congenital Long QT Syndrome (LQTS) Type 3 in a patient with treatment resistant schizophrenia and no known personal or family history of cardiac disease. The patient in this Case Report had a hidden genetic condition revealed only following the essential administration of antipsychotics. As a result, this patient experienced an aborted cardiac arrest and a total of five episodes of ventricular tachycardia (VT) requiring cardioversion. Successful control of the VT occurred with an Automatic Internal Defibrillator (AID), judicious use of antipsychotic medications, and anti-arrhythmic medications...
December 20, 2016: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/27996316/developmental-coordination-disorder-plus-oculomotor-and-visuospatial-impairment-as-neurodevelopmental-heralds-of-psychosis-proneness
#16
Michele Poletti, Eva Gebhardt, Andrea Raballo
Aiming at preventing transitions to more severe psychopathology and boosted by the availability of operational criteria to identify help-seeking subjects at increased risk for psychosis, research into the early prodromal phases of psychosis is attracting a growing clinical interest. Furthermore, the focus of early detection is gradually shifting from prodromal syndromes to the premorbid period. Although mainly driven by clinical-pragatic aims, such a shift is coherent with the neurodevelopmental hypothesis of schizophrenia that might offer a unifying, developmentally informed conceptual framework for early detection...
December 20, 2016: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/27996315/unusual-psychotic-presentation-after-discontinuation-of-treatment-in-a-patient-with-wilson-s-disease-a-case-report
#17
Andreas S Lappas, Fiesal Jan
Psychiatric manifestations are common in patients with Wilson's Disease(WD), and they are usually correlated with neurological symptoms. However, psychotic presentation without neurological symptoms has rarely been reported. We present a case of WD involving a 34-year-old gentleman who was diagnosed at the age of 22, but due to lack of medication for approximately 5 months was admitted in a psychiatric ward with delusional thoughts of grandeur and persecution, echopraxia and echolalia. No neurological impairment, ophthalmic manifestations or liver abnormalities were identified...
December 20, 2016: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/27996314/the-problem-of-missed-mental-health-care-appointments
#18
Marilyn J Miller, Donna M Ambrose
Missed appointments are a problem in all types of outpatient clinics including those providing mental health care. A review of literature was conducted to explore the problem of missed appointments in mental health and identify methods that have been used to improve attendance. Study results demonstrate that patients miss appointments for many reasons. Common reasons for missed appointments in the articles reviewed were the interval between scheduling and appointment day, forgetting, being discharged against medical advice, and problems with substance abuse...
December 20, 2016: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/27454216/myocarditis-in-a-patient-on-clozapine-what-did-it
#19
Sahil Munjal, Stephen Ferrando
We are presenting a case of 37-year-old male with schizoaffective disorder who developed myocarditis within 3 weeks of starting on clozapine for his treatment resistant psychosis. The patient also had a positive titer for Influenza A which makes it a diagnostic dilemma regarding the cause of his myocarditis. It may be possible that the myocarditis was caused by the Influenza A virus or synergistically exacerbated the clozapine's propensity to cause it. Currently, there are no studies establishing the link between the two etiologies...
July 25, 2016: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/27454215/catatonia-and-psychosis-related-to-epilepsy-a-case-report
#20
Laiana Quagliato, Roberto Piedade, Cristina Santana, Elie Cheniaux
Although a variety of metabolic, toxic, psychiatric, and neurologic conditions can produce catatonic syndromes, it is less widely recognized that this state may be caused by epilepsy. We present the case of a woman with catatonic behavior, which she could not recall. She also exhibited olfactory, auditory and visual hallucinations. An EEG demonstrated diffuse abnormal electrical activity, mainly on left temporal and frontal areas. Treatment with anticonvulsant drugs yielded excellent response.
July 25, 2016: Clinical Schizophrenia & related Psychoses
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