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Recent Patents on Biotechnology

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https://www.readbyqxmd.com/read/29473528/novel-genetic-tool-to-study-the-stability-of-genomic-islands
#1
Ashok Kumar, Satyabrata Bag, Bhabatosh Das
BACKGROUND: Genomic islands (GIs) are discrete segments of mobile DNA with defined boundaries, acquired in the bacterial genome from another organism by horizontal gene transfer during the course of evolution. GIs contribute significantly in virulence, disease development, antimicrobial resistance and metabolic process. OBJECTIVE: The present study focuses on the development of a vector based genetic tool carrying selectable and counter-selectable markers, in order to flag the GIs in the bacterial chromosome and monitor their stability in laboratory growth conditions...
February 22, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29384069/exploration-of-global-trend-on-biomedical-application-of-polyhydroxyalkanoate-pha-a-patent-survey
#2
Paulraj Ponnaiah, Nagiah Vnoothenei, Muruganandham Chandramohan, Mohamed Javad Pazhayakath Thevarkattil
BACKGROUND: Polyhydroxyalkanoates are bio-based, biodegradable naturally occurring polymers produced by a wide range of organisms, from bacteria to higher mammals. The properties and biocompatibility of PHA make it possible for a wide spectrum of applications. In this context, we analyze the potential applications of PHA in biomedical science by exploring the global trend through the patent survey. The survey suggests that PHA is an attractive candidate in such a way that their applications are widely distributed in the medical industry, drug delivery system, dental material, tissue engineering, packaging material as well as other useful products...
January 30, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29366430/distribution-and-characterization-of-the-vitis-vinifera-l-subsp-sylvestris-in-southern-tuscany
#3
Monica Scali, Rita Vignani, Andrea Zifferero
BACKGROUND: The Eurasian grapevine is the most widespread fruit crop in the world. Numerous studies have focused on clarifying the events of domestication and the geographical areas in which they occurred. OBJECTIVES: In order to add upon information on the process of grapevine domestication, the distribution and genetic diversity of a small, wild population localized in Poggio Ghiaccio Forte, an archaeological site in Maremma (Southern Tuscany), were assessed. In a preliminary survey the wild forms of Vitis vinifera L...
January 24, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29295701/evaluation-of-fibroblasts-cells-viability-and-adhesion-on-six-different-titanium-surfaces-an-in-vitro-experimental-study
#4
Sergio Alexandre Gehrke, Leticia Perez-Diaz, Berenice Anina Dedavid
BACKGROUND: The topographical surficial characteristics and properties of materials can induce different cell reactions regards to the viability and adhesion according to the recent patents. The aim of this in vitro experimental study was to evaluate the viability and adhesion of fibroblastic cells seeded on titanium disks with different surface topography. In addition, we revised all patents relating to sintering process titanium powder surface treatment for a of dental implants. METHODS: Fibroblast cells were cultured on 6 surfaces models: mA disks corresponding to titanium surfaces without additional treatment (machined surface) were compared with mB disks, where surfaces were sandblasting etching using aluminum oxide; mC disks where titanium oxide was used for sandblasting etching; mD disks where triple acid conditioning was used, mE disks with laser treated surface and mF disks which were made of titanium powder by a sintering process...
January 1, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29210667/nerolidol-and-its-pharmacological-application-in-treating-neurodegenerative-diseases-a-review
#5
Rusbene Bruno Fonseca De Carvalho, Antonia Amanda Cardoso De Almeida, Neylon Barbosa Campelo, Daniel Ramon Oliveira Dantas Lellis, Livio Cesar Cunha Nunes
BACKGROUND: Research on natural bioactive compounds has increased exponentially over the last decades. The discovery of new phytochemicals that possess pharmaceutical properties is useful in the development of therapeutic alternatives. The nerolidol (3,7,11-trimetil-1,6,10-dodecatrien-3-ol or 3,7,11-trimetildodeca-1,6,10-trien-3-ol) has been extensively studied for its therapeutic potential because of its pharmacological activities in the treatment of neurodegenerative diseases. METHODS: All articles and patents regarding to nerolidol and its pharmacological properties were revised, focusing mainly on the important properties in the treatment of neurodegenerative diseases...
December 6, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29189184/impact-of-electron-beam-irradiation-on-functional-attributes-of-seeds-of-two-coastal-wild-legume-landraces-of-canavalia
#6
Kandikere R Sridhar, Prabhavathi Supriya, Sudeep D Ghate
BACKGROUND: Vegetable proteins have widespread application in the food industry as functional ingredients in food formulations according to the recent patents. Requirement to develop less expensive protein-rich supplementary foods has resulted in shift of emphasis towards lesser known wild than popular legumes. OBJECTIVE: The aim of this study is to expose seeds of two coastal sand dune wild legumes of the Southwest India (Canavalia cathartica and C. maritima) to different doses of electron-beam (EB) irradiation to assess changes in functional attributes...
November 29, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29290179/preface
#7
Nikolaos E Labrou
No abstract text is available yet for this article.
2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29173192/the-ecstacy-of-gold-patent-expirations-for-trastuzumab-bevacizumab-rituximab-and-cetuximab
#8
Tasha R Serna-Gallegos, Krishnansu S Tewari, Christopher J LaFargue
BACKGROUND: Fully humanized monoclonal antibodies have revolutionized the treatment of many solid tumors, including breast, lung, colorectal, and ovarian cancer. Among the most widely used monoclonal antibodies in clinical oncology are cetuximab, trastuzumab, rituximab, and bevacizumab. OBJECTIVE: This article will review these four notable monoclonal antibodies, their role in clinical oncology, and the drug patents that are nearing expiration. RESULTS: They are used in both first and second line treatment regimens for multiple common malignancies...
November 22, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29173191/relevant-patented-biotechnological-applications-of-ecotin-an-update
#9
Moez Rhimi, Nizar Akermi, Hela Mkaouar, Amin Jeblaoui, Aicha Kriaa, Ali Gargouri, Emmanuelle Maguin
BACKGROUND: Ecotins are serine protease inhibitors which are generally found in the periplasmic compartment. These inhibitors act on a wide range of serine proteases with different efficiencies. Actually, only few Ecotins were studied, and the main characterized proteins derived from Escherichia coli. Functional studies of this latter protein allowed the development of numerous patents related to Ecotin relevant biotechnological applications. OBJECTIVE: This review aims to give an update on the relevant Ecotins already described and to provide a concise overview concerning the relevant patented applications of these serine protease inhibitors...
November 22, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29065846/computational-determination-of-the-effects-of-bacteriophage-bacteriophage-interactions-in-human-body
#10
Marwa Mostafa Mostafa, Mohammad Nassef, Amr Badr
BACKGROUND: Chronic diseases are becoming more serious and widely spreading and this carries a heavy burden on doctors to deal with such patients. Although many of these diseases can be treated by bacteriophages, the situation is significantly dangerous in patients having concomitant more than one chronic disease, where conflicts between phages used in treating these diseases are very closer to happen. METHOD: This research paper presents a method to detecting the Bacteriophage-Bacteriophage Interaction...
October 19, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28925862/biofactories-for-the-production-of-recombinant-phytases-and-its-application-in-animal-feed-industry
#11
Thais P P de Souza, Resyla M da Mariano, Mariana S Vieira, Suliana F V Andrade, Renato R Godoi, Ana Flavia A Gonçalves, Luciana P Naves, William J N Lima, Daniel B Gonçalves, Mariana Campos da Paz, Alexsandro S Galdino
BACKGROUND: Phytases are enzymes capable of degrading phytic acid and are used in animal feed supplementation in order to improve digestibility through the release of minerals such as phosphorus. Recent inventions show interest in production and optimization of recombinant phytases with biochemical and physicochemical characteristics promising for animal feed industry. METHODS: This review article is focused on relevant patents of the promising phytases, as well as the commonly used expression systems for its production, and also the tools currently used to generate new phytases...
September 15, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28799489/toward-enhancing-the-enzymatic-activity-of-a-novel-fungal-polygalacturonase-for-food-industry-optimization-and-biochemical-analyses
#12
Yousseria M H Shetaia, Ashraf F El-Baz, Ahmed M ElMekawy
BACKGROUND: The review of literature and patents shows that enhancing the PG production and activity are still required to fulfill the increasing demands. METHODS: A dual optimization process, which involved Plackett-Burman design (PBD), with seven factors, and response surface methodology, was applied to optimize the production of extracellular polygalacturonase (PG) enzyme produced by a novel strain of Aspergillus flavus isolated from rotten orange fruit. The fungal PG was purified and biochemically characterized...
August 11, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28707577/high-performance-enzyme-free-glucose-sensor-with-co-cu-nanorod-arrays-on-si-substrates
#13
Haji Shirinzadeh, Abolfazl Yazdanpanah, Dimitrios Karponis, Behzad Aghabarari, Mohammad Tahmasbi, Alexander Seifalian, Masoud Mozafari
BACKGROUND: Glucose sensors have been extensively researched and manufactured a tool for clinical diabetes diagnosis. Although some kinds of electrochemical enzymatic glucose sensors have been commercially successful, however, there is still room for improvement, in selectivity and reliability of these sensors. Because of the intrinsic disadvantages of enzymes, such as high fabrication cost and poor stability, non-enzymatic glucose sensors have recently promoted as next generation diagnostic tool due to their relatively low cost, high stability, prompt response, and accuracy...
July 13, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28641511/microbial-lipase-mediated-by-health-beneficial-modification-of-cholesterol-and-flavors-in-food-products-a-review
#14
Ranjana Sharma, Nivedita Sharma
BACKGROUND: The tremendous need of lipase in varied applications in biotechnological increases its economical value in food and allied industries. Lipase has an impressive number of applications viz. enhancements of flavor in food products (Cheese, butter, alcoholic beverages, milk chocolate and diet control food stuffs), detergent industry in removing oil, grease stain, organic chemical processing, textile industry, oleochemical industry, cosmetic industry and also as therapeutic agents in pharmaceutical industries...
June 14, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28606046/converting-enzymes-into-tools-of-industrial-importance
#15
Ipsita Roy, Shivcharan Prasad
The term enzyme ('in yeast') was first used by Wilhelm Kuhne while describing the ability of yeast to produce alcohol from sugars. Since then, there has been a determined effort to use enzymes for catalysing reactions. When compared with chemical catalysts, enzymes offer very high selectivity when acting as catalysts. This could be in terms of chemo- (functional group), regio- (positional) or stereo- (chirality) selectivity. Such selectivity yields a product which is free from impurities; the cost of the product is also reduced as the number of steps is less...
June 12, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28558635/recent-technology-development-for-the-biosynthesis-of-human-milk-oligosaccharide
#16
Ningzi Guan, Rachel Chen
Human milk oligosaccharide (HMO) is a third most abundant component in breast milk. HMOs are molecules naturally tailored to the need of an infant. They protect infants from diseases, foster healthy gastrointestinal systems, reinforce fledgling immune function, and promote early brain development. Supplementing HMOs to infant formulae, which lack this critical element, would substantially improve the function of formulae. Overwhelming evidences also indicate that HMOs can be used for the treatment of arthritis and related autoimmune disease, and inhibition of bacteria adhesion or as potential prebiotics...
May 30, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28494723/recent-advances-in-vaccines-against-leishmania-based-on-patent-applications
#17
Vanete Thomaz-Soccol, Eduardo Scopel Ferreira da Costa, Susan Grace Karp, Luiz Alberto Junior Letti, Carlos Ricardo Soccol, Flavia Thomaz
Leishmaniasis is a chronic disease affecting over 12 million people, worldwide, present in 98 countries. It has no definitive cure, and its treatment is severe to patient's health. Several attempts have been made in order to find a way to prevent the infection, as a vaccination method. However, there is no licensed vaccine for human use, up to date. The main goal of this study is to present a short review of patents relating to vaccines against Leishmania parasites. This review covers some important statistics of patent applications, giving insights on the technology maturity and which countries have been more active in the pursue of a vaccine...
May 10, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28474559/new-prospective-for-enhancement-in-bioenergy-resources-through-fungal-engineering
#18
Rafia Azmat, Sumeira Moin, Ailyan Saleem, Neelofer Hamid, Anum Khursheed, Waseem Ahmed
BACKGROUND: Lignin and cellulose, organic constituents of plant or plant based material not commonly used for feeding purpose are referred as Biomass. This can be used as best resource of renewable energy. Vesicular arbuscular mycorrhizae (VAM) fungi can play an effective role in biomass manufacturing through activated metabolism of plant under dual symbiosis. During C acclimatization, mycorrhizal inoculated plants existent greater number of leaves with height of plants as compared to non-mycorrhizal plants...
May 3, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28474558/analysis-of-recent-patenting-activities-on-the-field-of-bioremediation-of-petroleum-hydrocarbon-pollutants-present-in-the-environment
#19
Hari Prasanna Deka Boruah, Jijnasa Bordoloi
BACKGROUND: In today's world one of the major environmental problems is the contamination of aquatic or terrestrial ecosystem due to spillage of hydrocarbon compounds produced due to various activities related to the petrochemical industry. In recent years, bioremediation has been emerged as a promising technology for the restoration of these contaminated sites in an eco friendly way. OBJECTIVE: The aim of present review literature is the compilation of patent documents on bioremediation of petroleum hydrocarbon pollutants to know the technological advancements in this field...
May 3, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28413994/biological-methods-for-heavy-metal-decontamination-a-patent-review
#20
Vinay Sharma, Rupesh K Mishra
BACKGROUND: In the modern age of globalization and fast industrialization, the environmental matters are fetching more and more annoyance for human being. Heavy metals occur in immobilized form in sediments and as aggregates in nature. However due to the different human activities like ore mining and industrial processes, the natural biogeochemical cycles are disordered instigating amplified deposition of heavy metals in aquatic environments. The most common pollution causing heavy metals are considered to be the mercury, arsenic, lead, copper, silver, cadmium...
April 17, 2017: Recent Patents on Biotechnology
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