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Recent Patents on Biotechnology

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https://www.readbyqxmd.com/read/29866025/patent-landscape-on-structured-lipids-produced-by-enzyme-technology
#1
Emilia Akil, Elisa d'Avila Costa Cavalcanti, Sabrina Dias de Oliveira, Priscilla Filomena Fonseca Amaral, Denise Maria Guimaraes Freire, Alexandre Guedes Torres
BACKGROUND: Lipid modification results in several benefits for the food industry, biotechnology advances and human health. Customizing bioactive lipids is very appealing because it improves the product's nutritional quality. Lipases are sustainable biocatalysts that can be reused, show selectivity towards substrates and reactions occur in mild conditions. OBJECTIVES: We aimed at systematically searching for patents deposited worldwide, that approached the production of structured lipids by using lipases as biocatalysts...
June 3, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29848255/geochemical-cycle-of-radon-and-its-bioremediation-opportunity-from-water-environment-a-review
#2
Debabrata Pradhan, Lala Behari Sukla, Niharbala Devi, Sridhara Acharya
BACKGROUND: The waterborne or airborne radon causes carcinogenesis in the human bodies due to the continuous decay of α- and β- particles. The health risks related to radioactive radon instigate to develop an advanced technology for its removal from the environment. There are two standard tech-niques, such as aeration and activated carbon filtration, available for its removal. However, both of them face different technological drawbacks resulting in the processes either inefficient or inappropriate for the purpose...
May 1, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29564989/lateral-flow-assay-for-interleukin-6-a-technological-and-scientific-prospection-of-a-10-year-survey
#3
Ingridi Souza Sene, Vladimir Costa Silva, Gisele Elias Nunes Pauli, Ivan Helmuth Bechtold, Livio Cesar Cunha Nunes, Carla Eiras, Carlos Henrique Nery Costa
BACKGROUND: Interleukin-6 (IL-6) is a multifunctional cytokine that plays a crucial role not only in the immune system, but also in numerous biological processes. Elevated IL-6 levels have been observed in many types of cancer and inflammatory diseases. Among the techniques that have been used to quantify IL-6, a Lateral Flow Assay (LFA) is one of the most promising. OBJECTIVE: The objective of this study was to perform a technological and scientific exploration of the development of a LFA for IL-6...
March 20, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29473528/novel-genetic-tool-to-study-the-stability-of-genomic-islands
#4
Ashok Kumar, Satyabrata Bag, Bhabatosh Das
BACKGROUND: Genomic islands (GIs) are discrete segments of mobile DNA with defined boundaries, acquired in the bacterial genome from another organism by horizontal gene transfer during the course of evolution. GIs contribute significantly in virulence, disease development, antimicrobial resistance and metabolic process. OBJECTIVE: The present study focuses on the development of a vector based genetic tool carrying selectable and counter-selectable markers, in order to flag the GIs in the bacterial chromosome and monitor their stability in laboratory growth conditions...
February 22, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29384069/exploration-of-global-trend-on-biomedical-application-of-polyhydroxyalkanoate-pha-a-patent-survey
#5
Paulraj Ponnaiah, Nagiah Vnoothenei, Muruganandham Chandramohan, Mohamed Javad Pazhayakath Thevarkattil
BACKGROUND: Polyhydroxyalkanoates are bio-based, biodegradable naturally occurring polymers produced by a wide range of organisms, from bacteria to higher mammals. The properties and biocompatibility of PHA make it possible for a wide spectrum of applications. In this context, we analyze the potential applications of PHA in biomedical science by exploring the global trend through the patent survey. The survey suggests that PHA is an attractive candidate in such a way that their applications are widely distributed in the medical industry, drug delivery system, dental material, tissue engineering, packaging material as well as other useful products...
January 30, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29366430/distribution-and-characterization-of-the-vitis-vinifera-l-subsp-sylvestris-in-southern-tuscany
#6
Monica Scali, Andrea Zifferero, Rita Vignani
BACKGROUND: The Eurasian grapevine is the most widespread fruit crop in the world. Numerous studies have focused on clarifying the events of domestication and the geographical areas in which they occurred. OBJECTIVES: In order to add upon information on the process of grapevine domestication, the distribution and genetic diversity of a small, wild population localized in Poggio Ghiaccio Forte, an archaeological site in Maremma (Southern Tuscany), were assessed. In a preliminary survey the wild forms of Vitis vinifera L...
January 24, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29295701/evaluation-of-fibroblasts-cells-viability-and-adhesion-on-six-different-titanium-surfaces-an-in-vitro-experimental-study
#7
Sergio Alexandre Gehrke, Leticia Perez-Diaz, Berenice Anina Dedavid
BACKGROUND: The topographical surficial characteristics and properties of materials can induce different cell reactions regards to the viability and adhesion according to the recent patents. The aim of this in vitro experimental study was to evaluate the viability and adhesion of fibroblastic cells seeded on titanium disks with different surface topography. In addition, we revised all patents relating to sintering process titanium powder surface treatment for a of dental implants. METHODS: Fibroblast cells were cultured on 6 surfaces models: mA disks corresponding to titanium surfaces without additional treatment (machined surface) were compared with mB disks, where surfaces were sandblasting etching using aluminum oxide; mC disks where titanium oxide was used for sandblasting etching; mD disks where triple acid conditioning was used, mE disks with laser treated surface and mF disks which were made of titanium powder by a sintering process...
January 1, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28606046/converting-enzymes-into-tools-of-industrial-importance
#8
Shivcharan Prasad, Ipsita Roy
BACKGROUND: Enzymes have applications in numerous biotechnological products and processes that are commonly used in the production of food and beverages, cleaning supplies, clothing, paper products, transportation fuels, pharmaceuticals, and monitoring devices. Enzymes, however, are optimized to function under physiological conditions. Any change in reaction conditions results in their activity as well as stability being compromised. Hence, most of the natural biomolecules are not suitable for industrial applications...
2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28474559/new-prospective-for-enhancement-in-bioenergy-resources-through-fungal-engineering
#9
Rafia Azmat, Sumeira Moin, Ailyan Saleem, Neelofer Hamid, Anum Khursheed, Waseem Ahmed
BACKGROUND: Lignin and cellulose, organic constituents of the plant or plant-based material not commonly used for feeding purpose are referred as Biomass. Patents suggest that this can be used as the best resource of renewable energy. Vesicular Arbuscular Mycorrhizae (VAM) fungi can play an effective role in biomass manufacturing through activated metabolism of the plant under dual symbiosis. During C acclimatization, mycorrhizal inoculated plants existent greater number of leaves with a height of plants as compared to non-mycorrhizal plants...
2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28474558/analysis-of-recent-patenting-activities-in-the-field-of-bioremediation-of-petroleum-hydrocarbon-pollutants-present-in-the-environment
#10
Jijnasa Bordoloi, H P Deka Boruah
BACKGROUND: In today's world one of the major environmental problems is the contamination of aquatic or terrestrial ecosystem due to spillage of hydrocarbon compounds produced due to various activities related to the petrochemical industry. In recent years, bioremediation has emerged as a promising technology for the restoration of these contaminated sites in an ecofriendly way. OBJECTIVE: The aim of present review literature is the compilation of patent documents on bioremediation of petroleum hydrocarbon pollutants to know technological advancements in this field...
2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28317492/monoclonal-antibodies-production-against-a-40kda-band-of-hydatid-cyst-fluid
#11
Seyedeh Maryam Sharafi, Hedayat Shirzad, Hossein Khanahmad, Behrooz Ataei, Hossein Yousofi Darani
BACKGROUND AND OBJECTIVES: Hydatid cyst is the larval stage of the tapeworm Echinococcus granulosus. Hydatid cyst fluid, cyst membrane and Protoscolices, contain a complex mixture of antigens that can induce immune responses in the host. Anti-cancer properties of Protoscolices and hydatid cyst fluid has been shown. In order to identify antigens of hydatid cyst fluid that have anti-cancer effect, in this study production of monoclonal antibodies against one of the hydatid cyst fluid band (40KDa) has been investigated...
2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29210667/nerolidol-and-its-pharmacological-application-in-treating-neurodegenerative-diseases-a-review
#12
Rusbene Bruno Fonseca De Carvalho, Antonia Amanda Cardoso De Almeida, Neylon Barbosa Campelo, Daniel Ramon Oliveira Dantas Lellis, Livio Cesar Cunha Nunes
BACKGROUND: Research on natural bioactive compounds has increased exponentially over the last decades. The discovery of new phytochemicals that possess pharmaceutical properties is useful in the development of therapeutic alternatives. The nerolidol (3,7,11-trimetil-1,6,10-dodecatrien-3-ol or 3,7,11-trimetildodeca-1,6,10-trien-3-ol) has been extensively studied for its therapeutic potential because of its pharmacological activities in the treatment of neurodegenerative diseases. METHODS: All articles and patents regarding to nerolidol and its pharmacological properties were revised, focusing mainly on the important properties in the treatment of neurodegenerative diseases...
December 6, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29189184/impact-of-electron-beam-irradiation-on-functional-attributes-of-seeds-of-two-coastal-wild-legume-landraces-of-canavalia
#13
Kandikere R Sridhar, Prabhavathi Supriya, Sudeep D Ghate
BACKGROUND: Vegetable proteins have widespread application in the food industry as functional ingredients in food formulations according to the recent patents. Requirement to develop less expensive protein-rich supplementary foods has resulted in shift of emphasis towards lesser known wild than popular legumes. OBJECTIVE: The aim of this study is to expose seeds of two coastal sand dune wild legumes of the Southwest India (Canavalia cathartica and C. maritima) to different doses of electron-beam (EB) irradiation to assess changes in functional attributes...
November 29, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29173192/the-ecstacy-of-gold-patent-expirations-for-trastuzumab-bevacizumab-rituximab-and-cetuximab
#14
Tasha R Serna-Gallegos, Christopher J LaFargue, Krishnansu S Tewari
BACKGROUND: Fully humanized monoclonal antibodies have revolutionized the treatment of many solid tumors, including breast, lung, colorectal, and ovarian cancer. Among the most widely used monoclonal antibodies in clinical oncology are cetuximab, trastuzumab, rituximab, and bevacizumab. OBJECTIVE: This article will review these four notable monoclonal antibodies, their role in clinical oncology, and the drug patents that are nearing expiration. RESULTS: They are used in both first and second line treatment regimens for multiple common malignancies...
November 22, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29173191/relevant-patented-biotechnological-applications-of-ecotin-an-update
#15
Nizar Akermi, Hela Mkaouar, Amin Jeblaoui, Aicha Kriaa, Ali Gargouri, Emmanuelle Maguin, Moez Rhimi
BACKGROUND: Ecotins are serine protease inhibitors which are generally found in the periplasmic compartment. These inhibitors act on a wide range of serine proteases with different efficiencies. Actually, only few Ecotins were studied, and the main characterized proteins derived from Escherichia coli. Functional studies of this latter protein allowed the development of numerous patents related to Ecotin relevant biotechnological applications. OBJECTIVE: This review aims to give an update on the relevant Ecotins already described and to provide a concise overview concerning the relevant patented applications of these serine protease inhibitors...
November 22, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29065846/computational-determination-of-the-effects-of-bacteriophage-bacteriophage-interactions-in-human-body
#16
Marwa Mostafa Mostafa, Mohammad Nassef, Amr Badr
BACKGROUND: Chronic diseases are becoming more serious and widely spreading and this carries a heavy burden on doctors to deal with such patients. Although many of these diseases can be treated by bacteriophages, the situation is significantly dangerous in patients having concomitant more than one chronic disease, where conflicts between phages used in treating these diseases are very closer to happen. METHOD: This research paper presents a method to detecting the Bacteriophage-Bacteriophage Interaction...
October 19, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28925862/biofactories-for-the-production-of-recombinant-phytases-and-its-application-in-animal-feed-industry
#17
Thais P P de Souza, Resyla M da Mariano, Mariana S Vieira, Suliana F V Andrade, Renato R Godoi, Ana Flavia A Gonçalves, Luciana P Naves, William J N Lima, Daniel B Gonçalves, Mariana Campos da Paz, Alexsandro S Galdino
BACKGROUND: Phytases are enzymes capable of degrading phytic acid and are used in animal feed supplementation in order to improve digestibility through the release of minerals such as phosphorus. Recent inventions show interest in production and optimization of recombinant phytases with biochemical and physicochemical characteristics promising for animal feed industry. METHODS: This review article is focused on relevant patents of the promising phytases, as well as the commonly used expression systems for its production, and also the tools currently used to generate new phytases...
September 15, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28799489/toward-enhancing-the-enzymatic-activity-of-a-novel-fungal-polygalacturonase-for-food-industry-optimization-and-biochemical-analyses
#18
Yousseria M H Shetaia, Ashraf F El-Baz, Ahmed M ElMekawy
BACKGROUND: The review of literature and patents shows that enhancing the PG production and activity are still required to fulfill the increasing demands. METHODS: A dual optimization process, which involved Plackett-Burman design (PBD), with seven factors, and response surface methodology, was applied to optimize the production of extracellular polygalacturonase (PG) enzyme produced by a novel strain of Aspergillus flavus isolated from rotten orange fruit. The fungal PG was purified and biochemically characterized...
August 11, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28707577/high-performance-enzyme-free-glucose-sensor-with-co-cu-nanorod-arrays-on-si-substrates
#19
Haji Shirinzadeh, Abolfazl Yazdanpanah, Dimitrios Karponis, Behzad Aghabarari, Mohammad Tahmasbi, Alexander Seifalian, Masoud Mozafari
BACKGROUND: Glucose sensors have been extensively researched and manufactured a tool for clinical diabetes diagnosis. Although some kinds of electrochemical enzymatic glucose sensors have been commercially successful, however, there is still room for improvement, in selectivity and reliability of these sensors. Because of the intrinsic disadvantages of enzymes, such as high fabrication cost and poor stability, non-enzymatic glucose sensors have recently promoted as next generation diagnostic tool due to their relatively low cost, high stability, prompt response, and accuracy...
July 13, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28641511/microbial-lipase-mediated-by-health-beneficial-modification-of-cholesterol-and-flavors-in-food-products-a-review
#20
Ranjana Sharma, Nivedita Sharma
BACKGROUND: The tremendous need of lipase in varied applications in biotechnological increases its economical value in food and allied industries. Lipase has an impressive number of applications viz. enhancements of flavor in food products (Cheese, butter, alcoholic beverages, milk chocolate and diet control food stuffs), detergent industry in removing oil, grease stain, organic chemical processing, textile industry, oleochemical industry, cosmetic industry and also as therapeutic agents in pharmaceutical industries...
June 14, 2017: Recent Patents on Biotechnology
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