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Recent Patents on Biotechnology

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https://www.readbyqxmd.com/read/28317492/monoclonal-antibodies-production-against-a-40kda-band-of-hydatid-cyst-fluid
#1
Hossein Yousofi Darani, Behroz Ataei, Seyedeh Maryam Sharafi, Hedayat Shirzad
BACKGROUND AND OBJECTIVES: Hydatid cyst is the larval stage of the tapeworm Echinococcus granulosus. Hydatid cyst fluid, cyst membrane and Protoscolices, contain a complex mixture of antigens that can induce immune responses in the host. Anti-cancer properties of Protoscolices and hydatid cyst fluid has been shown. In order to identify antigens of hydatid cyst fluid that have anti-cancer effect, in this study production of monoclonal antibodies against one of the hydatid cyst fluid band (40KDa) has been investigated...
March 17, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28260520/virus-based-rna-silencing-agents-and-virus-derived-expression-vectors-as-gene-therapy-vehicles
#2
Srividhya Venkataraman, Tauqeer Ahmad, Mounir G Abouhaidar, Kathleen L Hefferon
BACKGROUND: In consideration of recent developments in understanding the genomics and proteomics of viruses, the use of viral DNA / RNA sequences as well as their gene expression schemes, have found new in-roads towards the prognosis and therapy of diseases. Correspondingly, the sphere of the patenting scenario has expanded significantly. OBJECTIVES: The current review addresses patented inventions concerning the use of virus sequences as gene silencing machineries and inventions concerning the generation and application of viral sequences as expression vectors...
February 28, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28245777/the-metabolic-syndrome-and-the-relevance-of-nutrients-for-its-onset
#3
Andrea M P Romani, Lauren L Schnack
BACKGROUND: Metabolic Syndrome is a pathological condition characterized by the co-presence of various dysmetabolic and pathological processes including hypertension, dyslipidemia, type 2 diabetes mellitus, obesity, and cardiovascular complications. Because these conditions manifest themselves differently in a given patient, the ensuing pathophysiological state varies from patient to patient. Consequently, the order in which signs and symptoms manifest themselves can vary, making difficult to establish cause-effect relationship, and efficacious treatment and prevention options...
February 27, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28240191/biomolecules-for-removal-of-heavy-metal
#4
Namita Ashish Singh
Heavy metals are natural constituents of the earth's crust, but some heavy metals like cadmium, lead, mercury, arsenic etc. are injurious to living organisms at higher concentration. Nowadays, anthropogenic activities have altered geochemical cycles and biochemical balance of heavy metals. Biomolecules are used nowadays for removal of heavy metals compared to other synthetic biosorbents due to their environmental friendly nature and cost effectiveness. The goal of this work is to review research work and patents related to adsorption through biomolecules like polysaccharides, polypeptides, lignin etc...
February 23, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28219320/microorganism-and-agricultural-based-biosorbents-towards-removal-of-cadmium-from-waste-water-an-overview
#5
Souvik Pal, Subhankar Mukherjee, Nabarun Bhattacharyya
BACKGROUND: Non-degradable and persistent nature of Cadmium (Cd) poses high toxicity to human, plants and animals. Several industrial processes generated wastes are the main anthropogenic pathway through which Cd enters into the environment. Although, World Health Organization (WHO) has set the limit of Cd in drinking water is 0.005 mg L-1, the industrial activities release much higher concentrations of metal ions to the water stream than the prescribed limits, which leads to the increasing health hazards and environmental pollution...
February 20, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28215141/patents-on-endophytic-fungi
#6
Mamta S Gokhale, Diva Gupta, Umang Gupta, Rumana Faraz, Sardul Singh Sandhu
BACKGROUND: Endophytic fungi are taxonomically and ecologically heterogeneous group of organisms, mainly belonging to the Ascomycotina and Deuteromycotina. Endophytes usually produce the enzymes necessary for the colonization of plant tissues. Endophytes are able to utilize components of plant cells without disturbing host metabolism, which is confirmed by isozyme analysis and studies on substrate utilization. The patents related to enzymes and metabolites produced by endophytic fungi are associated with their ecological significance...
February 15, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28137207/patent-survey-of-resveratrol-taxol-podophyllotoxin-withanolides-and-their-derivatives-used-in-anticancer-therapy
#7
Krishnadas Nandagopal, Shreya Routh
BACKGROUND: Resveratrol, taxol, podophyllotoxin, withanolides and their derivatives find applications in anti-cancer therapy. They are plant-derived compounds whose chemical structures and synthesis limit their natural availability and restrict a large-scale industrial production. Hence, their production by various biotechnological approaches may hold promise for a continuous and reliable mode of supply. OBJECTIVE: We review process and product patents in this regard...
January 27, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28116999/microbes-in-heavy-metal-remediation-a-review-on-current-trends-and-patents
#8
Geetesh Kumar Mishra
BACKGROUND: Contamination of environmental samples like soil and groundwater by heavy metals is a widespread problem. Such a contamination of environmental matrices by toxic heavy metals arises as a result of many human activities which are largely driven by the industries, although sources such as agriculture and sewage disposal also contribute for the heavy metal contamination. Release of heavy metal containing waste without treatment to the environment poses a significant threat to public health and safety...
January 20, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28093973/adsorptive-removal-of-metal-ions-from-water-using-functionalized-biomaterials
#9
Kanchanmala Deshpande
BACKGROUND: Synthesis and modification of cost-effective sorbents for removing heavy metals from water resources is an area of significance. It had been reported that materials with biological origins, such as agricultural and animal waste, are excellent alternatives to conventional adsorbents due to their higher affinity, capacity and selectivity towards metal ions. These properties of biomaterials help to reduce or detoxify metal ions concentration in contaminated water to acceptable regulatory standards...
January 16, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28078979/biotechnological-patents-applications-of-the-deuterium-oxide-in-human-health
#10
Reysla M da S Mariano, Wendell C Bila, Maria Jaciara F Trindade, Joel Alves Lamounier, Alexsandro S Galdino
BACKGROUND: Deuterium oxide is a molecule that has been used for decades in several studies related to human health. Currently, studies on D2O have mobilized a "Race for Patenting" worldwide. Several patents have been registered from biomedical and technological studies of D2O showing the potential of this stable isotope in industry and health care ecosystems. METHODS: Most of the patents relating to applications of the deuterium oxide in human health have been summarized in this review...
January 12, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28078980/bioremediation-of-toxic-heavy-metals-a-patent-review
#11
Neelam Verma, Rajni Sharma
BACKGROUND: The global industrialization is fulfilling the demands of modern population at the cost of environmental exposure to various contaminants including heavy metals. These heavy metals affect water and soil quality. Moreover these enter into the food chain and exhibit their lethal effects on the human health even when present at slightly higher concentration than required for normal metabolism. To the worst of their part, the heavy metals may become carcinogenic. Henceforth, the efficient removal of heavy metals is the demand of sustainable development...
January 11, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28017124/measurement-of-scientific-productivity-in-r-d-sector-changing-paradigm
#12
Abhishek Kumar, Alpana Srivastava, R P Jeevan Kumar, Rajesh K Tiwari
Scientific Productivity is a demand of policy makers for a judicious utilization of massive R&D budget allocated and utilized. A huge mass of intellectual assets is employed, which after investing manpower, infrastructure and lab consumables demand for a major outcome which contributes towards building nation's economy. Scientific productivity was only measured thorough publications or patents. Patents, earmarked as a strong parameter for innovation generation, where, Word Intellectual Property Organisation generated a data on applications for the top 20 offices for patents, where Australia, Brazil and Canada occupied top 3 positions...
December 23, 2016: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/27903220/santavac-%C3%A2-a-novel-universal-antigen-composition-for-developing-cancer-vaccines
#13
Petr Genrievich Lokhov, Elena Evgenevna Balashova
BACKGROUND: Development of a universal cancer vaccine for the prevention of all cancers has been under development for many years. Antiangiogenic cancer vaccines elicit immune responses with the potential of destroying tumor vasculature endothelial cells without affecting vasculature integrity in normal tissues. The methods used in the development of antigen compositions comprising these vaccines have been recently improved and described in this report in the context of SANTAVAC ™ development - the first cancer vaccine based on endothelial cell heterogeneity...
November 30, 2016: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/27881055/patents-in-nanobiotechnology-a-cross-jurisdictional-approach
#14
Padmavati Manchikanti, Shailaja Gnaneshwar, B Ramesh Kumar
BACKGROUND: Bio nanomaterials create new opportunities for advancing medical sciences and diseases treatment in relation to human health care. Innovations in the use of such nanomaterials and nanodevices can lead to significant improvements in the use of drugs/devices. OBJECTIVE: The present study attempts to analyse patenting trends in different areas and compare the patentability criteria and the disclosure norms for nanobiotechnology inventions in countries such as US, EU and India in the field of diagnostics and therapeutics...
November 22, 2016: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/27842483/patents-on-therapeutic-and-cosmetic-applications-of-bioactives-of-crocus-sativus-l-and-their-production-through-synthetic-biology-methods-a-review
#15
Mitali Nitin Dawalbhakta, Manasi Alok Telang
BACKGROUND: Saffron (Crocus sativus L.) has a long history of use as a food additive and a traditional medicine for treating a number of disorders. Prominent bioactives of saffron are crocin, crocetin and safranal. OBJECTIVE: The aim of this study was to carry out an extensive patent search to collect information on saffron bioactives and their derivatives as therapeutic and cosmeceutical agents. All patents related to the area of interest published globally till date have been reviewed...
November 14, 2016: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/27686329/heavy-metal-concentrations-in-some-edible-vegetables-a-case-study-in-uyo-and-ibesikpo-asutan-local-government-areas-of-akwa-ibom-state
#16
Okpako Felix Ogbemudia, Iziegbe Lucky Igbinosun, Mathias Rufus Ubom, Tochi Grace Chilaka
BACKGROUND: This study assessed the level of heavy metals (Zn, Cu, Mn, Hg and Fe) accumulation in leaves of five vegetables viz: Telfairia occidentalis, Heinsia crinita, Gnetum africanum, Talinum triangulare and Vernonia amygdalina planted in different gardens in Ibesikpo Asutan and Uyo L.G.As in Akwa Ibom State, Nigeria using standard scientific methods. METHODS: Soil samples were obtained at a depth of 0 - 10 cm each at the base of each vegetable using soil auger...
September 27, 2016: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/27671490/cardioprotector-activity-of-an-esteroidal-saponin-a-scientific-and-technological-prospection
#17
Hercília Maria Lins Rolim, Michely Laiany Vieira Moura
Diosgenin (3b-hydroxy-5-spirostene), saponin is a steroid with wide therapeutic application in different areas, with cardiovascular protective action and performance in the control of dyslipidemia. The objective of study was to conduct a systematic review of this Diosgenina, its pharmaceutical applications and the outlook on the application in Cardiovascular System diseases. Periodicals bases, such as ScienceDirect, PubMed and Virtual Health Library, were used, as well as technological basis of European Patent Office, World Intellectual Property Organization, United States Patent and Trademark Office and data bank from Brazilian National Institute of Industrial Property...
September 26, 2016: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/27494086/molecular-genetic-approaches-for-environmental-stress-tolerant-crop-plants-progress-and-prospects
#18
Ranjeet Kaur, Ananta Kumar Ghosh, Rupam Kumar Bhunia
Global food security is threatened by the severe environmental conditions that have reduced the worldwide crop yield. Plants possess inherent mechanisms to cope with the initial stress phase but to ensure their survival through harsh climate, the intervention of genetic engineering is desirable. Elucidation of genetic loci and deciphering the underlying mechanisms that confer tolerance to plants against stressful conditions followed by its successful introgression into elite, high-yielding crop varieties can be an effective way to engineer the crops for increasing productivity...
August 5, 2016: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/27494033/inactivation-of-pseudomonas-aeruginosa-by-chitosan-coated-iron-oxide-nanoparticles
#19
Sirshendu De, Munmun Mukherjee
BACKGROUND: Pseudomonas aeruginosa is one of the potent opportunistic pathogens associated with respiratory and urinary tract infection. The bacterium owes its pathogenicity due to the intrinsic resistance to antibiotics and disinfectants. OBJECTIVE: The present study is focused on the synthesis of antibacterial chitosan coated iron oxide nanoparticles for rapid inactivation of Pseudomonas aeruginosa. We have discussed the relevant patents on synthesis and antibacterial potential of metallic nanoparticles and chitosan...
August 5, 2016: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/27456823/acute-toxicity-of-the-pesticides-dichlorvos-and-lindane-against-the-african-air-breathing-catfish-heterobranchus-longifilis-valenciennes-1840-siluriformes-clariidae
#20
Oribhabor Blessing, Ikeogu C Grace
BACKGROUND: This study raises the awareness to the use of toxic pesticides and reiterates the well-known danger of these pesticides. The acute toxicity of two pesticides, dichlorvos and lindane against the African air-breathing catfish, Heterobranchus longifilis fingerlings was investigated under static bioassay in the laboratory. Relevant patents relating to acute toxicity of pesticides against fish were reviewed. Invention concerning the detection of biomarkers in material from a living organism relates to a method of testing whether a living organism has been exposed to stress, such as pesticide exposure...
July 25, 2016: Recent Patents on Biotechnology
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