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Recent Patents on Biotechnology

Krishnadas Nandagopal, Shreya Routh
BACKGROUND: Resveratrol, taxol, podophyllotoxin, withanolides and their derivatives find applications in anti-cancer therapy. They are plant-derived compounds whose chemical structures and synthesis limit their natural availability and restrict a large-scale industrial production. Hence, their production by various biotechnological approaches may hold promise for a continuous and reliable mode of supply. OBJECTIVE: We review process and product patents in this regard...
January 27, 2017: Recent Patents on Biotechnology
Geetesh Kumar Mishra
BACKGROUND: Contamination of environmental samples like soil and groundwater by heavy metals is a widespread problem. Such a contamination of environmental matrices by toxic heavy metals arises as a result of many human activities which are largely driven by the industries, although sources such as agriculture and sewage disposal also contribute for the heavy metal contamination. Release of heavy metal containing waste without treatment to the environment poses a significant threat to public health and safety...
January 20, 2017: Recent Patents on Biotechnology
Kanchanmala Deshpande
BACKGROUND: Synthesis and modification of cost-effective sorbents for removing heavy metals from water resources is an area of significance. It had been reported that materials with biological origins, such as agricultural and animal waste, are excellent alternatives to conventional adsorbents due to their higher affinity, capacity and selectivity towards metal ions. These properties of biomaterials help to reduce or detoxify metal ions concentration in contaminated water to acceptable regulatory standards...
January 16, 2017: Recent Patents on Biotechnology
Alexsandro S Galdino, Reysla M da S Mariano, Wendell C Bila, Maria Jaciara F Trindade, Joel Alves Lamounier
BACKGROUND: Deuterium oxide is a molecule that has been used for decades in several studies related to human health. Currently, studies on D2O have mobilized a "Race for Patenting" worldwide. Several patents have been registered from biomedical and technological studies of D2O showing the potential of this stable isotope in industry and health care ecosystems. METHODS: Most of the patents relating to applications of the deuterium oxide in human health have been summarized in this review...
January 12, 2017: Recent Patents on Biotechnology
Neelam Verma, Rajni Sharma
BACKGROUND: The global industrialization is fulfilling the demands of modern population at the cost of environmental exposure to various contaminants including heavy metals. These heavy metals affect water and soil quality. Moreover these enter into the food chain and exhibit their lethal effects on the human health even when present at slightly higher concentration than required for normal metabolism. To the worst of their part, the heavy metals may become carcinogenic. Henceforth, the efficient removal of heavy metals is the demand of sustainable development...
January 11, 2017: Recent Patents on Biotechnology
Abhishek Kumar, Alpana Srivastava, R P Jeevan Kumar, Rajesh K Tiwari
Scientific Productivity is a demand of policy makers for a judicious utilization of massive R&D budget allocated and utilized. A huge mass of intellectual assets is employed, which after investing manpower, infrastructure and lab consumables demand for a major outcome which contributes towards building nation's economy. Scientific productivity was only measured thorough publications or patents. Patents, earmarked as a strong parameter for innovation generation, where, Word Intellectual Property Organisation generated a data on applications for the top 20 offices for patents, where Australia, Brazil and Canada occupied top 3 positions...
December 23, 2016: Recent Patents on Biotechnology
Petr Genrievich Lokhov, Elena Evgenevna Balashova
BACKGROUND: Development of a universal cancer vaccine for the prevention of all cancers has been under development for many years. Antiangiogenic cancer vaccines elicit immune responses with the potential of destroying tumor vasculature endothelial cells without affecting vasculature integrity in normal tissues. The methods used in the development of antigen compositions comprising these vaccines have been recently improved and described in this report in the context of SANTAVAC ™ development - the first cancer vaccine based on endothelial cell heterogeneity...
November 30, 2016: Recent Patents on Biotechnology
Padmavati Manchikanti, Shailaja Gnaneshwar, B Ramesh Kumar
BACKGROUND: Bio nanomaterials create new opportunities for advancing medical sciences and diseases treatment in relation to human health care. Innovations in the use of such nanomaterials and nanodevices can lead to significant improvements in the use of drugs/devices. OBJECTIVE: The present study attempts to analyse patenting trends in different areas and compare the patentability criteria and the disclosure norms for nanobiotechnology inventions in countries such as US, EU and India in the field of diagnostics and therapeutics...
November 22, 2016: Recent Patents on Biotechnology
Mitali Nitin Dawalbhakta, Manasi Alok Telang
BACKGROUND: Saffron (Crocus sativus L.) has a long history of use as a food additive and a traditional medicine for treating a number of disorders. Prominent bioactives of saffron are crocin, crocetin and safranal. OBJECTIVE: The aim of this study was to carry out an extensive patent search to collect information on saffron bioactives and their derivatives as therapeutic and cosmeceutical agents. All patents related to the area of interest published globally till date have been reviewed...
November 14, 2016: Recent Patents on Biotechnology
Khushboo Gualti, Krishna Mohan Poluri
BACKGROUND: Unraveling the comprehensive networks of molecular signaling in various cellular processes and redesign/rewire them as per human wish is the ultimate dream of the biomedical researchers. Recent advances in the experimental and computational biophysics have provided us with enormous amount of protein sequences and a wide variety of structural information. Protein engineering is a fledging field and a creative process to design the target proteins or signaling networks with desirable structure and functions...
October 13, 2016: Recent Patents on Biotechnology
Okpako Felix Ogbemudia, Iziegbe Lucky Igbinosun, Mathias Rufus Ubom, Tochi Grace Chilaka
BACKGROUND: This study assessed the level of heavy metals (Zn, Cu, Mn, Hg and Fe) accumulation in leaves of five vegetables viz: Telfairia occidentalis, Heinsia crinita, Gnetum africanum, Talinum triangulare and Vernonia amygdalina planted in different gardens in Ibesikpo Asutan and Uyo L.G.As in Akwa Ibom State, Nigeria using standard scientific methods. METHODS: Soil samples were obtained at a depth of 0 - 10 cm each at the base of each vegetable using soil auger...
September 27, 2016: Recent Patents on Biotechnology
Hercília Maria Lins Rolim, Michely Laiany Vieira Moura
Diosgenin (3b-hydroxy-5-spirostene), saponin is a steroid with wide therapeutic application in different areas, with cardiovascular protective action and performance in the control of dyslipidemia. The objective of study was to conduct a systematic review of this Diosgenina, its pharmaceutical applications and the outlook on the application in Cardiovascular System diseases. Periodicals bases, such as ScienceDirect, PubMed and Virtual Health Library, were used, as well as technological basis of European Patent Office, World Intellectual Property Organization, United States Patent and Trademark Office and data bank from Brazilian National Institute of Industrial Property...
September 26, 2016: Recent Patents on Biotechnology
Hudu Garba Mikail, David Dezi Akumka, Muhammed Adamu
BACKGROUND: Local anaesthetics provide relief from pain when applied locally to nerve tissue by blocking conduction of sensory nerve impulse from the receptor to the brain cortex. OBJECTIVE: This study aimed at evaluating local anaesthetic activity of the methanolic leaves extract of Lannea schimperi. METHODS: Six groups of five animals were used; groups I-IV were used for intracutaneous wheal test in guinea pigs for infiltration anaesthesia, while group V and VI were used for guinea pig corneal reflex method of surface anaesthesia...
September 22, 2016: Recent Patents on Biotechnology
Nsikak O Abiaobo, Sifon Udi, Ofonmbuk I Obot
The concentration of five heavy metals; Cadmium (Cd), Copper (Cu), Lead (Pb), Mercury (Hg) and Zinc (Zn) in the tissues of periwinkle; Typanotonus fuscatus from Iko River Estuary were determined using UNICAM Solar Atomic Absorption Spectrophotometer 969 model. The results showed that Cd ranged from 68.83 - 130.5mg/kg with a mean value of 104.47±23.85mg/kg, Cu ranged from 34.9 - 73.62mg/kg with a mean value of 57.70±17.19mg/kg, Pb ranged between 54.27 - 102.54mg/kg with a mean value of 85.03±18.52mg/kg, Mercury ranged from 0...
September 22, 2016: Recent Patents on Biotechnology
Ranjeet Kaur, Ananta Kumar Ghosh, Rupam Kumar Bhunia
Global food security is threatened by the severe environmental conditions that have reduced the worldwide crop yield. Plants possess inherent mechanisms to cope with the initial stress phase but to ensure their survival through harsh climate, the intervention of genetic engineering is desirable. Elucidation of genetic loci and deciphering the underlying mechanisms that confer tolerance to plants against stressful conditions followed by its successful introgression into elite, high-yielding crop varieties can be an effective way to engineer the crops for increasing productivity...
August 5, 2016: Recent Patents on Biotechnology
Sirshendu De, Munmun Mukherjee
BACKGROUND: Pseudomonas aeruginosa is one of the potent opportunistic pathogens associated with respiratory and urinary tract infection. The bacterium owes its pathogenicity due to the intrinsic resistance to antibiotics and disinfectants. OBJECTIVE: The present study is focused on the synthesis of antibacterial chitosan coated iron oxide nanoparticles for rapid inactivation of Pseudomonas aeruginosa. We have discussed the relevant patents on synthesis and antibacterial potential of metallic nanoparticles and chitosan...
August 5, 2016: Recent Patents on Biotechnology
Oribhabor Blessing, Ikeogu C Grace
BACKGROUND: This study raises the awareness to the use of toxic pesticides and reiterates the well-known danger of these pesticides. The acute toxicity of two pesticides, dichlorvos and lindane against the African air-breathing catfish, Heterobranchus longifilis fingerlings was investigated under static bioassay in the laboratory. Relevant patents relating to acute toxicity of pesticides against fish were reviewed. Invention concerning the detection of biomarkers in material from a living organism relates to a method of testing whether a living organism has been exposed to stress, such as pesticide exposure...
July 25, 2016: Recent Patents on Biotechnology
Tridib Kumar Goswami
No abstract text is available yet for this article.
2016: Recent Patents on Biotechnology
Nikolaos E Labrou
No abstract text is available yet for this article.
2016: Recent Patents on Biotechnology
Zeeshan Fatima, Rahul Pal, Moiz Ashraf Ansari, Saif Hameed
BACKGROUND: Infections caused by Mycobacterium and pathogenic fungi have risen drastically over the past few decades. Moreover, with the increase in the number of immunocompromised (burn, organ transplant, chemotherapy, HIV) patients, these bacterial and fungal infections have led to alarming mortality rates. The drugs currently in use have become relatively ineffective due to ever increasing phenomenon of multidrug resistance. Furthermore, these drugs suffer with severe toxicity effects and also lack cost effectiveness...
2016: Recent Patents on Biotechnology
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