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Recent Patents on Biotechnology

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https://www.readbyqxmd.com/read/28799489/toward-enhancing-the-enzymatic-activity-of-a-novel-fungal-polygalacturonase-for-food-industry-optimization-and-biochemical-analyses
#1
Yousseria M H Shetaia, Ashraf F El-Baz, Ahmed M ElMekawy
BACKGROUND: The review of literature and patents shows that enhancing the PG production and activity are still required to fulfill the increasing demands. METHODS: A dual optimization process, which involved Plackett-Burman design (PBD), with seven factors, and response surface methodology, was applied to optimize the production of extracellular polygalacturonase (PG) enzyme produced by a novel strain of Aspergillus flavus isolated from rotten orange fruit. The fungal PG was purified and biochemically characterized...
August 11, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28707577/high-performance-enzyme-free-glucose-sensor-with-co-cu-nanorod-arrays-on-si-substrates
#2
Alexander Marcus Seifalian, Haji Shirinzadeh, Abolfazl Yazdanpanah, Dimitrios Karponis, Mohammad Tahmasbi, Masoud Mozafari
BACKGROUND: Glucose sensors have been extensively researched and manufactured a tool for clinical diabetes diagnosis. Although some kinds of electrochemical enzymatic glucose sensors have been commercially successful, however, there is still room for improvement, in selectivity and reliability of these sensors. Because of the intrinsic disadvantages of enzymes, such as high fabrication cost and poor stability, non-enzymatic glucose sensors have recently promoted as next generation diagnostic tool due to their relatively low cost, high stability, prompt response, and accuracy...
July 13, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28641511/microbial-lipase-mediated-by-health-beneficial-modification-of-cholesterol-and-flavors-in-food-products-a-review
#3
Ranjana Sharma, Nivedita Sharma
BACKGROUND: The tremendous need of lipase in varied applications in biotechnological increases its economical value in food and allied industries. Lipase has an impressive number of applications viz. enhancements of flavor in food products (Cheese, butter, alcoholic beverages, milk chocolate and diet control food stuffs), detergent industry in removing oil, grease stain, organic chemical processing, textile industry, oleochemical industry, cosmetic industry and also as therapeutic agents in pharmaceutical industries...
June 14, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28606046/converting-enzymes-into-tools-of-industrial-importance
#4
Ipsita Roy, Shivcharan Prasad
The term enzyme ('in yeast') was first used by Wilhelm Kuhne while describing the ability of yeast to produce alcohol from sugars. Since then, there has been a determined effort to use enzymes for catalysing reactions. When compared with chemical catalysts, enzymes offer very high selectivity when acting as catalysts. This could be in terms of chemo- (functional group), regio- (positional) or stereo- (chirality) selectivity. Such selectivity yields a product which is free from impurities; the cost of the product is also reduced as the number of steps is less...
June 12, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28558635/recent-technology-development-for-the-biosynthesis-of-human-milk-oligosaccharide
#5
Ningzi Guan, Rachel Chen
Human milk oligosaccharide (HMO) is a third most abundant component in breast milk. HMOs are molecules naturally tailored to the need of an infant. They protect infants from diseases, foster healthy gastrointestinal systems, reinforce fledgling immune function, and promote early brain development. Supplementing HMOs to infant formulae, which lack this critical element, would substantially improve the function of formulae. Overwhelming evidences also indicate that HMOs can be used for the treatment of arthritis and related autoimmune disease, and inhibition of bacteria adhesion or as potential prebiotics...
May 30, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28494723/recent-advances-in-vaccines-against-leishmania-based-on-patent-applications
#6
Vanete Thomaz-Soccol, Eduardo Scopel Ferreira da Costa, Susan Grace Karp, Luiz Alberto Junior Letti, Carlos Ricardo Soccol, Flavia Thomaz
Leishmaniasis is a chronic disease affecting over 12 million people, worldwide, present in 98 countries. It has no definitive cure, and its treatment is severe to patient's health. Several attempts have been made in order to find a way to prevent the infection, as a vaccination method. However, there is no licensed vaccine for human use, up to date. The main goal of this study is to present a short review of patents relating to vaccines against Leishmania parasites. This review covers some important statistics of patent applications, giving insights on the technology maturity and which countries have been more active in the pursue of a vaccine...
May 10, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28474559/new-prospective-for-enhancement-in-bioenergy-resources-through-fungal-engineering
#7
Rafia Azmat, Sumeira Moin, Ailyan Saleem, Neelofer Hamid, Anum Khursheed, Waseem Ahmed
BACKGROUND: Lignin and cellulose, organic constituents of plant or plant based material not commonly used for feeding purpose are referred as Biomass. This can be used as best resource of renewable energy. Vesicular arbuscular mycorrhizae (VAM) fungi can play an effective role in biomass manufacturing through activated metabolism of plant under dual symbiosis. During C acclimatization, mycorrhizal inoculated plants existent greater number of leaves with height of plants as compared to non-mycorrhizal plants...
May 3, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28474558/analysis-of-recent-patenting-activities-on-the-field-of-bioremediation-of-petroleum-hydrocarbon-pollutants-present-in-the-environment
#8
Hari Prasanna Deka Boruah, Jijnasa Bordoloi
BACKGROUND: In today's world one of the major environmental problems is the contamination of aquatic or terrestrial ecosystem due to spillage of hydrocarbon compounds produced due to various activities related to the petrochemical industry. In recent years, bioremediation has been emerged as a promising technology for the restoration of these contaminated sites in an eco friendly way. OBJECTIVE: The aim of present review literature is the compilation of patent documents on bioremediation of petroleum hydrocarbon pollutants to know the technological advancements in this field...
May 3, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28413994/biological-methods-for-heavy-metal-decontamination-a-patent-review
#9
Vinay Sharma, Rupesh K Mishra
BACKGROUND: In the modern age of globalization and fast industrialization, the environmental matters are fetching more and more annoyance for human being. Heavy metals occur in immobilized form in sediments and as aggregates in nature. However due to the different human activities like ore mining and industrial processes, the natural biogeochemical cycles are disordered instigating amplified deposition of heavy metals in aquatic environments. The most common pollution causing heavy metals are considered to be the mercury, arsenic, lead, copper, silver, cadmium...
April 17, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28317492/monoclonal-antibodies-production-against-a-40kda-band-of-hydatid-cyst-fluid
#10
Hossein Yousofi Darani, Behroz Ataei, Seyedeh Maryam Sharafi, Hedayat Shirzad
BACKGROUND AND OBJECTIVES: Hydatid cyst is the larval stage of the tapeworm Echinococcus granulosus. Hydatid cyst fluid, cyst membrane and Protoscolices, contain a complex mixture of antigens that can induce immune responses in the host. Anti-cancer properties of Protoscolices and hydatid cyst fluid has been shown. In order to identify antigens of hydatid cyst fluid that have anti-cancer effect, in this study production of monoclonal antibodies against one of the hydatid cyst fluid band (40KDa) has been investigated...
March 17, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28260520/virus-based-rna-silencing-agents-and-virus-derived-expression-vectors-as-gene-therapy-vehicles
#11
Srividhya Venkataraman, Tauqeer Ahmad, Mounir G Abouhaidar, Kathleen L Hefferon
BACKGROUND: In consideration of recent developments in understanding the genomics and proteomics of viruses, the use of viral DNA / RNA sequences as well as their gene expression schemes, have found new in-roads towards the prognosis and therapy of diseases. Correspondingly, the sphere of the patenting scenario has expanded significantly. OBJECTIVES: The current review addresses patented inventions concerning the use of virus sequences as gene silencing machineries and inventions concerning the generation and application of viral sequences as expression vectors...
February 28, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28245777/the-metabolic-syndrome-and-the-relevance-of-nutrients-for-its-onset
#12
Andrea M P Romani, Lauren L Schnack
BACKGROUND: Metabolic Syndrome is a pathological condition characterized by the co-presence of various dysmetabolic and pathological processes including hypertension, dyslipidemia, type 2 diabetes mellitus, obesity, and cardiovascular complications. Because these conditions manifest themselves differently in a given patient, the ensuing pathophysiological state varies from patient to patient. Consequently, the order in which signs and symptoms manifest themselves can vary, making difficult to establish cause-effect relationship, and efficacious treatment and prevention options...
February 27, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28240191/biomolecules-for-removal-of-heavy-metal
#13
Namita Ashish Singh
Heavy metals are natural constituents of the earth's crust, but some heavy metals like cadmium, lead, mercury, arsenic etc. are injurious to living organisms at higher concentration. Nowadays, anthropogenic activities have altered geochemical cycles and biochemical balance of heavy metals. Biomolecules are used nowadays for removal of heavy metals compared to other synthetic biosorbents due to their environmental friendly nature and cost effectiveness. The goal of this work is to review research work and patents related to adsorption through biomolecules like polysaccharides, polypeptides, lignin etc...
February 23, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28219320/microorganism-and-agricultural-based-biosorbents-towards-removal-of-cadmium-from-waste-water-an-overview
#14
Souvik Pal, Subhankar Mukherjee, Nabarun Bhattacharyya
BACKGROUND: Non-degradable and persistent nature of Cadmium (Cd) poses high toxicity to human, plants and animals. Several industrial processes generated wastes are the main anthropogenic pathway through which Cd enters into the environment. Although, World Health Organization (WHO) has set the limit of Cd in drinking water is 0.005 mg L-1, the industrial activities release much higher concentrations of metal ions to the water stream than the prescribed limits, which leads to the increasing health hazards and environmental pollution...
February 20, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28215141/patents-on-endophytic-fungi
#15
Mamta S Gokhale, Diva Gupta, Umang Gupta, Rumana Faraz, Sardul Singh Sandhu
BACKGROUND: Endophytic fungi are taxonomically and ecologically heterogeneous group of organisms, mainly belonging to the Ascomycotina and Deuteromycotina. Endophytes usually produce the enzymes necessary for the colonization of plant tissues. Endophytes are able to utilize components of plant cells without disturbing host metabolism, which is confirmed by isozyme analysis and studies on substrate utilization. The patents related to enzymes and metabolites produced by endophytic fungi are associated with their ecological significance...
February 15, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28137207/patent-survey-of-resveratrol-taxol-podophyllotoxin-withanolides-and-their-derivatives-used-in-anticancer-therapy
#16
Krishnadas Nandagopal, Shreya Routh
BACKGROUND: Resveratrol, taxol, podophyllotoxin, withanolides and their derivatives find applications in anti-cancer therapy. They are plant-derived compounds whose chemical structures and synthesis limit their natural availability and restrict a large-scale industrial production. Hence, their production by various biotechnological approaches may hold promise for a continuous and reliable mode of supply. OBJECTIVE: We review process and product patents in this regard...
January 27, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28116999/microbes-in-heavy-metal-remediation-a-review-on-current-trends-and-patents
#17
Geetesh Kumar Mishra
BACKGROUND: Contamination of environmental samples like soil and groundwater by heavy metals is a widespread problem. Such a contamination of environmental matrices by toxic heavy metals arises as a result of many human activities which are largely driven by the industries, although sources such as agriculture and sewage disposal also contribute for the heavy metal contamination. Release of heavy metal containing waste without treatment to the environment poses a significant threat to public health and safety...
January 20, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28093973/adsorptive-removal-of-metal-ions-from-water-using-functionalized-biomaterials
#18
Kanchanmala Deshpande
BACKGROUND: Synthesis and modification of cost-effective sorbents for removing heavy metals from water resources is an area of significance. It had been reported that materials with biological origins, such as agricultural and animal waste, are excellent alternatives to conventional adsorbents due to their higher affinity, capacity and selectivity towards metal ions. These properties of biomaterials help to reduce or detoxify metal ions concentration in contaminated water to acceptable regulatory standards...
January 16, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28078979/biotechnological-patents-applications-of-the-deuterium-oxide-in-human-health
#19
Reysla M da S Mariano, Wendell C Bila, Maria Jaciara F Trindade, Joel Alves Lamounier, Alexsandro S Galdino
BACKGROUND: Deuterium oxide is a molecule that has been used for decades in several studies related to human health. Currently, studies on D2O have mobilized a "Race for Patenting" worldwide. Several patents have been registered from biomedical and technological studies of D2O showing the potential of this stable isotope in industry and health care ecosystems. METHODS: Most of the patents relating to applications of the deuterium oxide in human health have been summarized in this review...
January 12, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28078980/bioremediation-of-toxic-heavy-metals-a-patent-review
#20
Neelam Verma, Rajni Sharma
BACKGROUND: The global industrialization is fulfilling the demands of modern population at the cost of environmental exposure to various contaminants including heavy metals. These heavy metals affect water and soil quality. Moreover these enter into the food chain and exhibit their lethal effects on the human health even when present at slightly higher concentration than required for normal metabolism. To the worst of their part, the heavy metals may become carcinogenic. Henceforth, the efficient removal of heavy metals is the demand of sustainable development...
January 11, 2017: Recent Patents on Biotechnology
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