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Asian Journal of Transfusion Science

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https://www.readbyqxmd.com/read/28970700/use-of-smartphone-technology-for-managing-workload-in-transfusion-transmissible-infection-nucleic-acid-testing-laboratory-for-platelet-concentrate-inventory-management-resulting-in-timely-issue-of-platelets-experience-from-a-tertiary-care-center
#1
Rekha Hans, Suresh Sharma, Neelam Marwaha, Suchet Sachdev, Hari Krishan Dhawan, Ashish Jain, Ratti Ram Sharma
No abstract text is available yet for this article.
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970699/hello%C3%A2-there-is-a-blob-of-quark-in-my-cryo-bag
#2
Atul Sonker, Anju Dubey, Rajendra Chaudhary
No abstract text is available yet for this article.
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970698/adding-up-the-evidence-trigger-for-prophylactic-plasma-transfusion
#3
Manish Raturi, Shamee Shastry, Poornima B Baliga
No abstract text is available yet for this article.
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970697/hiv-risk-associated-with-nucleic-acid-testing-tested-seronegative-blood-donation-where-the-donor-was-not-preassessed-for-the-risk
#4
Kanjaksha Ghosh, Kanchan Misra
No abstract text is available yet for this article.
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970696/out-of-the-blue-blue-blood
#5
Lenin Babu Elakkumanan, Jayasree Cherukat, Jane Nithya Tolson, Sarath Sistla, Abhishekh Basavarajegowda
No abstract text is available yet for this article.
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970695/interference-of-daratumumab-with-pretransfusion-testing-mimicking-a-high-titer-low-avidity-like-antibody
#6
Mei-Hwa Lin, Fei-Yun Liu, Hsiu-Mien Wang, Hsin-Ching Cho, Shyh-Chyi Lo
Daratumumab is a monoclonal immunoglobulin against CD38 and has been approved for treating patients with refractory multiple myeloma. The presence of daratumumab in the sera can interfere with pretransfusion testing due to the weakly expression of CD38 on red cells. The reactivity could be mistaken as autoantibody (if autocontrol is positive) or alloantibody (if autocontrol is negative). We present a case that demonstrates daratumumab could mimic a high titer low avidity (HTLA) alloantibody. A 34-year-old male patient of refractory myeloma was recruited in phase three clinical trial involving daratumumab...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970694/daily-plasma-exchange-in-severe-guillain-barr%C3%A3-syndrome-helps-in-early-weaning-from-ventilator-a-lesson-from-a-case
#7
Arunpreet Kaur, Archana Bajpayee, Nitin Kumar Bajpai, Nikhil Kothari
Intravenous immunoglobulin (IVIG) and therapeutic plasma exchange (TPE) are well-known therapeutic modalities in Guillain-Barré syndrome (GBS). In developing countries like India, where plasma-derived products (IVIG) are not easily available, and affordable TPE is preferred. Here, we reported a case of severe GBS, who was treated with daily plasma exchange (PLEX) rather than recommended alternate day schedule. A 16-year-old male adolescent of severe GBS, i.e., on mechanical ventilator was treated with the plasmapheresis regimen consisted of removal of 1...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970693/acute-respiratory-distress-syndrome-in-a-neonate-due-to-possible-transfusion-related-acute-lung-injury
#8
Arti Maria, Sheetal Agarwal, Anu Sharma
Transfusion-related acute lung injury (TRALI) is a potentially life-threatening complication of blood component transfusion. It is relatively underdiagnosed entity in neonates with scant literature. We report a case of TRALI in a preterm neonate developing acute respiratory distress within 6 h of blood product transfusion in the absence of preexisting lung disease. Prompt ventilator and supportive management were instituted. The baby showed clinical and radiological improvement within 12 h; however, he succumbed to death due to acute massive pulmonary hemorrhage 36 h later...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970692/coinheritance-of-hemoglobin-d-punjab-and-%C3%AE-0-thalassemia-3-4-kb-deletion-in-a-thai-girl
#9
Sitthichai Panyasai, Sarinna Rahad, Sakorn Pornprasert
Hemoglobin (Hb) D. Punjab [β121(GH4) Glu→Gln; HBB: C.364G>C] and β(0)-thalassemia 3.4 kb deletion are very rare in the Thai population. For the first time, the coinheritance of HbD-Punjab with β(0)-thalassemia 3.4 kb deletion was reported in a 7-year-old Thai girl. She had mild anemia (Hb 115.0 g/L and mean corpuscular hemoglobin 18.1 pg) with red blood cell microcytosis (mean corpuscular volume 52.5 fL). By capillary electrophoresis (CE), HbD-Punjab was found at a migration position of 180 s with the value of 81...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970691/autoimmune-hemolytic-anemia-caused-by-anti-e-a-challenge-a-case-report-with-review-of-literature
#10
Sangeeta Pahuja, Deepti Verma
Autoimmune hemolytic anemia (AIHA) is featured by short red cell survival due to autoantibodies. AIHA caused by anti 'e' is a tough clinical situation as antigen 'e' is a highly prevalent antigen. The present case highlights the same and different issues related to it.
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970690/successful-surgical-procedure-in-a-patient-of-aplastic-anemia-with-platelet-refractoriness-using-cross-match-compatible-platelets
#11
Ritam Chakrabarty, Sudipta Sekhar Das
This case marks the beginning of issuing cross-matched platelet products in Eastern India. A known case of aplastic anemia, on regular transfusion support, now presented with obstructed ventral periumbilical hernia requiring urgent surgical intervention. Platelet count at presentation was 13,000/μL. Platelet cross-matching was done by solid phase method. Ten units of random donor platelets were crossmatched. Five units were compatible and transfused. Counts rose to 84,000/μL after 1 h. Surgery was completed successfully...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970689/the-prozone-effect-exerted-by-the-complement-binding-anti-le-a-on-anti-d
#12
Sanmukh R Joshi, Kamlesh H Parekh
BACKGROUND: Prozone phenomenon is seen with very high-titer antibodies in an immune serum. AIM: The prozone effect on anti-D by a low-titer anti-Le(a) was investigated associated with neonatal jaundice. MATERIALS AND METHODS: Standard methods were used in investigations. RESULTS: The child was born at full-term developed mild jaundice. With weak direct antiglobulin test+, her indirect serum bilirubin was progressed to 27...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970688/transfusion-related-adverse-reactions-in-pediatric-and-surgical-patients-at-a-tertiary-care-teaching-hospital-in-india
#13
Kunal J Ghataliya, Jigar D Kapadia, Mira K Desai, K M Mehariya, G H Rathod, Nidhi Bhatnagar, M D Gajjar
BACKGROUND: Use of blood and its components is lifesaving. However, their use is often associated with adverse events. OBJECTIVE: To analyze the pattern of adverse reactions associated with transfusion of blood and its components in pediatric and surgical patients at a tertiary care teaching hospital. MATERIALS AND METHODS: Patients receiving transfusion of blood or its components in a randomly selected unit each from Departments of Pediatrics, including thalassemia OPD and surgery, were monitored intensively for a period of 6 months...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970687/detection-of-t-and-b-cells-specific-complement-fixing-alloantibodies-using-flow-cytometry-a-diagnostic-approach-for-a-resource-limited-laboratory
#14
Dharmendra Jain, Pranav Dorwal, Amit Pande, Neetu Tyagi, Simmi Mehra, Vimarsh Raina
BACKGROUND AND OBJECTIVES: Various methods have been reported for the detection of antibodies in recipient sera, which can be human leukocyte antigens (HLAs) or non-HLA specific, complement- or noncomplement fixing, as well as donor T (HLA-Class-I) and/or B cell (HLA-Class-I and II) specific. These alloantibodies play a pivotal role in antibody-mediated renal transplantation rejection. Deposition of C4d in peritubular capillaries of a kidney biopsy is a marker of antibody-mediated rejection...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970686/knowledge-and-attitude-of-donating-and-using-cord-blood-for-transfusion-among-patients-attending-nnamdi-azikiwe-university-teaching-hospital-nnewi-south-east-nigeria
#15
Chide E Okocha, Nkiru N Ezeama, John C Aneke, Chinyere U Onubogu, Charles I Okafor, Chijioke G Egbunike
BACKGROUND: Allogeneic blood for transfusion is in short supply in most parts of the developing world. Cord blood for transfusion can be a significant source of blood supply to our health institutions. AIMS: This study aims to investigate the knowledge and attitude to the donation and use of umbilical cord blood (UCB) for transfusion among the patients receiving services in a tertiary health institution in South-East Nigeria. MATERIALS AND METHODS: This was a cross-sectional study; an anonymous structured questionnaire was used...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970685/therapeutic-leukocyte-reduction-for-acute-and-chronic-myeloid-leukemias-a-4-year-experience-from-an-oncology-center-in-india
#16
Anita A Tendulkar, Puneet A Jain, Abhaykumar Gupta, Nidhi Sharma, Anisha Navkudkar, Vijaya Patle
INTRODUCTION: Hyperleukocytosis (HL) and leukostasis seen in myeloid leukemias are a medical emergency. We present a case series of ten such patients in a 4-year period. Sixteen therapeutic leukocyte reduction (TLR) were done in ten cases along with other supportive measures. The American Society for Apheresis supports the routine implementation of TLR in cases of HL secondary to myeloid leukemias with signs of leukostasis. MATERIALS AND METHODS: The procedures were performed on the intermittent flow cell separator after discussion with the treating physician about patient's condition...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970684/insight-into-donor-deferral-pattern-based-on-peripheral-blood-counts-an-experience-from-south-pakistan
#17
Sadia Sultan, Syed Mohammed Irfan, Mohammad Amjad Baig, Syed Mohammad Usman, Umme Aiman Shirazi
BACKGROUND: Donor deferral owing to anemia is one of the major causative factors of temporary donor rejection, which is preventable and treatable. The basic knowledge about frequency, types, and severity of anemia among donors will help plan a strategy to promote donor recruitment and overall national health. OBJECTIVE: The objective of this study was to provide the predonation deferral rate of the healthy blood donors based on peripheral blood counts and second to determine the types of anemia along with its severity...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970683/rapid-dry-plasma-thawing-system-an-alternative-to-conventional-thawing-baths
#18
S Sanooja Pinki, Ganesh Mohan, Aboobacker Mohamed Rafi, Susheela Jacob Innah, Tom Thomas
BACKGROUND: Fresh frozen plasma (FFP) should be thawed before transfusing to the patient. Prolonged or uncontrolled thawing can denature plasma proteins. The potential risk of contamination by wet thawing had always been a point of concern. AIMS: Here, we compared and evaluated the effect of thawing on clotting factor activities by two different methods (wet and dry) and other factors such as risk of bacterial contamination, throughput, turnaround time, and efficacy of thawing...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970682/comparison-of-two-algorithms-to-confirm-and-discriminate-samples-initially-reactive-for-nucleic-acid-amplification-tests
#19
Aseem Kumar Tiwari, Ravi C Dara, Dinesh Arora, Geet Aggarwal, Ganesh Rawat, Vimarsh Raina
BACKGROUND: Blood centers in India have published individual donor nucleic acid testing (ID-NAT) data based on an algorithm (Algorithm A) where serologically negative, NAT reactive sample was subsequently tested with discriminatory NAT (d-NAT), and on the basis of d-NAT, initial reactive samples were classified as "NAT yield" or inconclusive. We followed Algorithm B based on replicate testing and Ultrio Plus assay and compared the results with Algorithm A with Ultrio assay. MATERIALS AND METHODS: Results of ID-NAT using two algorithms were analyzed...
July 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28970681/evaluation-of-process-excellence-tools-in-improving-donor-flow-management-in-a-tertiary-care-hospital-in-south-india
#20
Divya Venugopal, Aboobacker Mohamed Rafi, Susheela Jacob Innah, Bibin T Puthayath
BACKGROUND: Process Excellence is a value based approach and focuses on standardizing work processes by eliminating the non-value added processes, identify process improving methodologies and maximize capacity and expertise of the staff. AIM AND OBJECTIVES: To Evaluate the utility of Process Excellence Tools in improving Donor Flow Management in a Tertiary care Hospital by studying the current state of donor movement within the blood bank and providing recommendations for eliminating the wait times and to improve the process and workflow...
July 2017: Asian Journal of Transfusion Science
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