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Asian Journal of Transfusion Science

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https://www.readbyqxmd.com/read/27605861/knowledge-and-awareness-among-nurses-regarding-the-blood-transfusion-services-and-practices-in-a-tertiary-care-teaching-hospital
#1
Shweta Talati, Anil Kumar Gupta, Ashish Jain
No abstract text is available yet for this article.
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605860/delayed-hemolytic-transfusion-reaction-due-to-anti-d-in-rh-d-positive-patient
#2
Deepti Sachan, Aswin S Kumar
No abstract text is available yet for this article.
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605859/validation-of-a-hemoglobinometer-for-use-in-outdoor-blood-donation-camps
#3
Anju Dubey, Saurabh Murti
No abstract text is available yet for this article.
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605858/direct-antiglobulin-test-positivity-in-multi-transfused-thalassemics
#4
Ashish Jain, Ajju Agnihotri, Neelam Marwaha, Ratti Ram Sharma
INTRODUCTION: Red cell allo- and auto-immunization is a well recognized problem in multi-transfused thalassemic patients. We conducted this study on 301 multi-transfused thalassemic patients under the Thalassemia Transfusion Programme of Advanced Pediatric Centre of PGIMER. AIMS AND OBJECTIVES: The study was designed to determine the frequency of alloimmunization and autoimmunization in multi-transfused thalassemic patients and to establish the specificity of alloantibody to red cell antigens, if alloimmunization is detected...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605857/anti-m-antibodies-biphasic-reactive-at-room-temperature-and-at-37%C3%A2-c-a-case-series
#5
Siddhi P Shah, Sangeeta M Kalgutkar, Rajesh B Sawant, Anand S Deshpande
Anti-M antibody, which is not reactive at 37°C, is not clinically significant. Reports of clinically significant anti-M antibodies causing hemolytic disease of the fetus and the newborn (HDFN) and delayed hemolytic transfusion reaction (DHTR) are available. We report 13 cases of anti-M antibodies reactive at room temperature (RT) and at 37°C. These were found in patients of varied age groups (11 months to 85 years) with varied clinical diagnosis. All the female patients were multigravida. In all cases, antibody screening was positive at RT as well as at the indirect antiglobulin test (IAT) phase...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605856/a-case-of-refractory-immune-thrombocytopenia-in-pregnancy-managed-with-elthrombopag
#6
Jyothis Purushothaman, Kochuthresia J Puthumana, Aswath Kumar, Susheela J Innah, Sareena Gilvaz
Immune thrombocytopenic purpura is a common acquired autoimmune disorder defined by a low platelet count secondary to accelerated platelet destruction or impaired thrombopoesis by anti-platelet antibodies. Thrombopoietin (TPO)-mimetic drugs such as eltrombopag and romiplostim have been used successfully in many nonpregnant individuals with immune thrombocytopenia (ITP) but studies based on its effects in pregnancy are limited. A 27-year-old multigravida who is a known case of ITP with bad obstetric history was referred to the Department of Obstetrics and Gynecology at 26 weeks of gestation with complaints of mucosal bleeding and recurrent abortions...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605855/anti-ih-an-antibody-worth-mention
#7
Nithya Mohanan, Nittin Henry, Aboobacker Mohamed Rafi, Susheela J Innah
A 72-year-old female with co-morbidities posted for surgical correction of fracture neck of femur without any history of transfusions was noted to have a hemoglobin level of 7 g/dl and packed red blood cells transfusion was ordered. Pretransfusion tests demonstrated A1B group with D positive on forward grouping. Reverse grouping showed a varying grade of agglutination with A, B, and O cells. Agglutination being stronger at 4°C. Antibody screening showed pan-agglutination, direct Coomb's test and auto control were negative...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605854/a-case-of-delayed-hemolytic-transfusion-reaction-in-sickle-cell-disease-patient
#8
Ashu Dogra, Meena Sidhu
Sickle cell disease (SCD) is autosomal recessive, genetically transmitted hemoglobinopathy responsible for considerable morbidity and mortality. It is prevalent in many parts of India including Central India, where the prevalence in different communities has ranged from 9.4% to 22%. Perioperative management may include transfusion of red blood cells. Hemolytic transfusion reactions can occur, and these can be either acute or delayed. We present a case of delayed hemolytic transfusion reaction in a patient with SCD...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605853/a-retrospective-review-of-cryoprecipitate-transfusion-practice-in-kuala-lumpur-hospital
#9
Intan Iliana Iliassa, Wan Mohd Zahiruddin Wan Mohammad, Jun Jie Tan, Yasmin Ayob
BACKGROUND: Cryoprecipitate is generally used to treat bleeding patients with hypofibrinogenemia, and the transfusion decision is guided based on published guidelines. AIM: This study aimed to evaluate the practice appropriateness in accordance to cryoprecipitate transfusion guidelines in Hospital Kuala Lumpur. METHODOLOGY: This cross-sectional study of 117 cryoprecipitates transfused adult patients was conducted in Kuala Lumpur Hospital from January to June 2012...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605852/impact-of-antigenic-exposures-and-role-of-molecular-blood-grouping-in-enhancing-transfusion-safety-in-chronically-transfused-thalassemics
#10
Raj Nath Makroo, Soma Agrawal, Aakanksha Bhatia, Mohit Chowdhry, Uday Kumar Thakur
BACKGROUND: Red cell alloimmunization is an acknowledged complication of blood transfusion. Current transfusion practices for thalassemia do not cater to this risk. Serological phenotyping is usually not reliable in these cases unless performed before the first transfusion. Under such circumstances, molecular blood grouping is an effective alternative. AIM: To perform molecular blood group genotyping in chronically transfused thalassemia patients and assess the risk of antigenic exposure and incidence of alloimmunization with current transfusion protocols...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605851/alloimmunization-in-multitransfused-liver-disease-patients-impact-of-underlying-disease
#11
Meenu Bajpai, Shruti Gupta, Priyanka Jain
INTRODUCTION: Transfusion support is vital to the management of patients with liver diseases. Repeated transfusions are associated with many risks such as transfusion-transmitted infection, transfusion immunomodulation, and alloimmunization. MATERIALS AND METHODS: A retrospective data analysis of antibody screening and identification was done from February 2012 to February 2014 to determine the frequency and specificity of irregular red-cell antibodies in multitransfused liver disease patients...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605850/a-study-on-confidential-unit-exclusion-at-shiraz-blood-transfusion-center-iran
#12
Leila Kasraian, Mohammad Hossein Karimi
BACKGROUND: Confidential unit exclusion (CUE) system has been designed to enhance transfusion safety as an extra additive approach. AIMS: This study was designed to survey demographic characteristics, prevalence of serologic markers, and reasons of opting CUE. MATERIALS AND METHODS: The cross-sectional study was performed at Shiraz Blood Transfusion Center (Southern Iran). CUE is used for all individuals who refer for blood donation, and donors can choose their blood not to be used if they have any doubt about their blood suitability for transfusion...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605849/evaluation-of-mirasol-pathogen-reduction-system-by-artificially-contaminating-platelet-concentrates-with-staphylococcus-epidermidis-a-pilot-study-from-india
#13
Kabita Chatterjee, Shamsuz Zaman, Rahul Chaurasia, Surinder Singh, Shawn D Keil, Shalini Tewari, Akanksha Bisht, Nitin Agarwal, Diptiranjan Rout, Subhash Chand, Kallol Saha
BACKGROUND AND OBJECTIVES: This study was conducted to assess the efficacy of Mirasol pathogen reduction system for platelets aimed at preventing bacterial regrowth by spiking buffy coat pooled platelets (BCPP) with clinically relevant load of Staphylococous epidermidis. MATERIALS AND METHODS: BCPP units were prepared using Teruflex BP-kit with Imugard III-S-PL (Terumo BCT, Tokyo, Japan). Two BCPP units were pooled, of which 40 ml of negative control (NC) was removed...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605848/blood-donor-selection-and-deferral-pattern-as-an-important-tool-for-blood-safety-in-a-tertiary-care-hospital
#14
Manisha Shrivastava, Nehal Shah, Seema Navaid, Kalpana Agarwal, Gourav Sharma
CONTEXT: Blood donor selection criteria based on science and regulatory rules influence donor as well recipient safety and demographics. AIM: To evaluate and analyze the blood donor deferral pattern and its causes among blood donors in a tertiary care hospital blood bank and to review its influence on blood safety. SETTINGS AND DESIGN: Hospital based blood bank, retrospective analysis. SUBJECTS AND METHODS: The data available as donor deferral record over a period of 13 years from 2001 to 2013 was analyzed...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605847/reducing-the-economic-burden-in-management-of-guillain-barre-syndrome-using-modified-plasmapheresis
#15
Rekha Ramaswamy Iyer, Pragnesh Hasmukhlal Shah, Sher Sankar K Roy, Sushil Kumar Kundanlal Suri
BACKGROUND: Guillain-Barre syndrome (GBS) is an autoimmune acute inflammatory demyelinating polyneuropathy affecting the peripheral nervous system treated with high-dose immunoglobulin, physical therapy, or plasmapheresis. Immunoglobulins are expensive and even plasmapheresis might not be affordable to patients visiting government set-ups. AIMS: This study was undertaken to emphasize the efficacy of plasmapheresis in treatment of adult GBS patients and to narrate methods of reducing the economic burden in the treatment of these patients using modified plasmapheresis...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605846/attitude-toward-blood-donation-among-medical-and-nonmedical-students-across-karachi
#16
Muhammad Osama Anwer, Shaikh Hamiz Ul Fawwad, Sanam Anwer, Arif Ali
AIM: To evaluate the factors that motivate and discourage medical and nonmedical students from donating blood voluntarily and to assess the level of awareness and knowledge regarding blood donation. MATERIALS AND METHODS: We conducted a cross-sectional descriptive study from August 2011 to May 2012 across different universities of Karachi covering both private and public sector. Predesigned questionnaires were filled by students. A total of 690 students participated in the study, 345 from each...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605845/thromboelastography-as-a-tool-for-quality-check-of-apheresis-platelets
#17
Anupam Verma, Dheeraj Khetan, Anubha Srivastava, Priti Elhence, Rahul Katharia
No abstract text is available yet for this article.
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27330251/is-cancer-chemotherapy-dying
#18
M B Agarwal
No abstract text is available yet for this article.
May 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27011683/prevalence-of-thalassemia-and-hemoglobinopathy-in-eastern-india-a-10-year-high-performance-liquid-chromatography-study-of-119-336-cases
#19
Santosh Kumar Mondal, Saikat Mandal
BACKGROUND: Hereditary hemoglobin (Hb) disorders are the most commonly encountered single gene disorders in India. Proper timely identification of these disorders is of paramount importance to prevent thalassemia major and clinically severe hemoglobinopathy as well as for epidemiologic purposes. AIMS: Our aim was to determine the prevalence of thalassemia and hemoglobinopathy in patients of a tertiary care hospital of West Bengal, India. MATERIALS AND METHODS: This prospective study was conducted on 119,336 cases over a period of 10 years...
January 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27011682/clinical-profile-of-hemophilia-patients-in-jodhpur-region
#20
Vikas Payal, Pramod Sharma, Vishnu Goyal, Rakesh Jora, Manish Parakh, Deepika Payal
BACKGROUND: Hemophilia is widely distributed all over the world, but little is known about its clinical profile in resource-limited regions. An insight into its clinical spectrum will help in the formulation of policies to improve the situation in these areas. AIMS: To study the clinical profile of hemophiliacs (age <18 years) in Jodhpur region and screen them for transfusion-transmitted infections. MATERIALS AND METHODS: A cross-sectional study conducted in the Department of Pediatrics, Umaid Hospital, Dr...
January 2016: Asian Journal of Transfusion Science
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