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Journals Asian Journal of Transfusion S...

Asian Journal of Transfusion Science

https://read.qxmd.com/read/37435611/47-th-annual-national-conference-of-indian-society-of-blood-transfusion-and-immunohaematology-isbti-transcon-2022-b-11-th-13-th-november-2022-jammu
#1
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
May 2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/37425099/write-up
#2
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
May 2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274979/human-leukocyte-antigen-alloimmunization-prevention-mechanisms-in-blood-transfusion
#3
REVIEW
Tiruneh Adane, Bamlaku Enawgaw
In many fields of clinical medicine and blood transfusion, the human leukocyte antigen (HLA) system is crucial. Alloimmunization happens as a result of an immune response to foreign antigens encountered during blood transfusion. This gives rise to alloantibodies against red blood cells (RBCs), HLA, or human platelet antigen (HPA). HLA alloimmunization following allogeneic transfusion was shown to be a result of contaminating white blood cells (WBCs) present in the product. It is a common complication of transfusion therapy that leads to difficulties in clinical intolerance and refractoriness to platelet transfusion during patient management...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274978/epidemiology-of-severe-acute-respiratory-syndrome-related-coronavirus-2-antibodies-in-healthy-blood-donors-and-their-follow-up
#4
JOURNAL ARTICLE
Rahul Chaurasia, Gopal Kumar Patidar, Hem Chandra Pandey, Suganya Palanisamy, Vidushi Gupta, Sapna Chopra, Poonam Coshic
BACKGROUND: Asymptomatic/presymptomatic COVID-19 affected individuals who may appear healthy during blood donor screening can donate blood despite being infective. Most blood donors in India are relatives/friends/acquaintances of patients, who under peer pressure overlook the donor selection process, which can significantly impact the transfusion safety. AIMS: The prevalence of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) antibodies among blood donors was assessed, along with the possible transmissibility of SARS-CoV-2 virus in transfusion recipients of blood components prepared from sero-reactive blood donors...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274977/hemolysis-in-reverse-grouping-evaluation-and-implication-of-high-titer-isoagglutinin-of-two-blood-donors
#5
Suman Sudha Routray, Sukanta Tripathy, Gopal Krushna Ray
Hemolysis is a positive agglutination reaction and is primarily associated with high anti-A or anti-B antibody titers. This high titer may result in no agglutination due to the "prozone" phenomenon. Platelet concentrate of high titer has an adverse effect on the recipient of the non-identical ABO blood group. Similarly, the blood products with higher titers of isoagglutinin have recently increased the incidence of intravenous immunoglobulins-related hemolysis. In this Asian subcontinent, the impact of O blood donors with high antibody titers or ABO incompatible platelets is hardly addressed...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274976/a-retrospective-study-to-assess-the-impact-of-abo-incompatibility-on-outcomes-of-allogeneic-peripheral-blood-stem-cell-transplants-at-a-tertiary-care-hospital-in-western-maharashtra
#6
JOURNAL ARTICLE
Balu B Nalukettil, Amit Kumar Biswas, Bhushan Asthana, Neerja Kushwaha, Ajay Kumar Baranwal, Sanjeevan Sharma
BACKGROUND: Hematopoietic stem cell transplantation (HSCT) has emerged as a curative measure for life-threatening hematological disorders. It can be autologous or allogeneic depending on the disease characteristics. Providing transfusion support to the transplant patients can be challenging, especially in AB-mismatched allogeneic HSCT. In this study, we investigated the impact of ABO incompatibility in patients undergoing allogeneic HSCT. MATERIALS AND METHODS: A retrospective review was conducted in 76 patients with hematological diseases who underwent allogeneic HSCT...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274975/intraoperative-blood-loss-and-blood-transfusion-requirement-among-liver-transplant-recipients-a-national-single-center-experience-2020
#7
JOURNAL ARTICLE
Mohd Faeiz Yusop, Norlida Mohamad Tahir, Sharifah Mai Sarah Syed Azim, Ameera Ashyila Kamaruzaman, Nur Raihan Mohd Hata, Arvend Kugaan, Mohd Fairuz Osman, Tengku Norita Tengku Yazid, Suryati Mokhtar, Haniza Omar, Ahmad Suhaimi Amir
BACKGROUND: Liver transplantation (LT) is a complicated surgical procedure with high risk for massive intraoperative blood loss due to pre-existing coagulopathy, portosystemic shunts with collateral circulations, and splenomegaly. The transfusion service will direct most of their resources toward LT programs with great impact on cost. The purpose of this study was to evaluate single center transfusion strategies and to identify the risk factors associated with the intraoperative blood loss and blood transfusion...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274974/association-of-donor-characteristics-with-coagulation-factor-levels-in-fresh-frozen-plasma
#8
JOURNAL ARTICLE
Sarika Agarwal, Gita Negi, Sushant Kumar Meinia, Eswara Prasad Chennamsetty, Daljit Kaur, Ashish Jain
BACKGROUND: Coagulation factors are essential to maintain normal hemostasis. Plasma for transfusion can be obtained from whole blood donation or plasma apheresis. Plasma obtained from whole blood donation is termed as fresh frozen plasma (FFP). The quality of FFP can be influenced by several factors including donor variables (such as age, gender, diet, genetic profile), environmental factors, collection methods, processing methods, storage temperature, etc. This study was done to assess the association of donor characteristics such as donor age, blood group, and smoking with coagulation factor levels in FFP units...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274973/allergic-reaction-to-heparin-gel-adding-agony-to-blood-donor
#9
JOURNAL ARTICLE
Deepti Sachan, Deepthi Krishna Gundrajukuppam, Kuralarasi Priyadarshini
No abstract text is available yet for this article.
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274972/clinical-and-laboratory-characteristics-of-patients-with-cold-agglutinin-disease-a-retrospective-analysis-at-a-tertiary-medical-center
#10
JOURNAL ARTICLE
Harshita Mehrotra, Zaher K Otrock
BACKGROUND: Cold agglutinin disease (CAD) is relatively rare and has primarily been reported as retrospective case series. AIM: We reviewed our experience with CAD to shed light on this disease. STUDY SETTINGS AND DESIGN: This was a retrospective review of all patients with CAD managed at our institution between 2007 and 2018. MATERIALS AND METHODS: The study was approved by our institutional review board. We extracted patients' demographic, clinical, and laboratory data, blood transfusions, and outcomes from their electronic medical records...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274971/hemolytic-disease-of-the-fetus-and-newborn-due-to-minor-blood-group-alloimmunization-in-a-mother-of-sickle-cell-disease-with-multiple-alloantibodies
#11
Stephy Varghese, Satya Prakash, Somnath Mukherjee, Ansuman Sahu, Debasish Mishra
Hemolytic disease of the fetus and newborn is due to maternal IgG antibodies that transport through the placenta and destroy neonatal red cells. A mismatch of antigens between mother and fetus causes isoimmunization resulting in mild anemia, which may progress to fetal hydrops in the intrauterine period and severe hyperbilirubinemia to kernicterus in neonates. The isoimmunization is mainly caused by Rh-D and ABO antibodies. In this case report, we found neonatal hyperbilirubinemia due to the presence of anti-c alloantibody previously developed in a sickle cell disease (SCD) pregnant female...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274970/application-of-blood-group-genotyping-in-complex-cases-of-immunohematology
#12
JOURNAL ARTICLE
Letícia Binhara Musial, Caroline Luise Prochaska, Mariane Faria Moss, Bruno Ribeiro Cruz
BACKGROUND: Red blood cell (RBC) group systems are depicted by antigens on the surface of RBCs, which when transfused to a recipient that lacks them, can result in alloimmunization. Thus, transfusion of matched RBC components to the recipient is recommended, especially for the more immunogenic blood group antigens, such as Rh (E, e, C, and c), Kell, Kidd, Duffy, and MNS. AIMS: The aim of this study was to perform the blood group genotyping from blood samples of 12 polytransfused patients whose phenotyping was inconclusive or incomplete...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274969/blood-component-therapy-in-patients-having-massive-obstetric-hemorrhage-in-a-tertiary-care-center-in-puducherry
#13
JOURNAL ARTICLE
S Anuragaa, Latha Chaturvedula, Abhishekh Basavarajegowda
INTRODUCTION: A proper transfusion protocol must be followed for every patient with massive obstetric hemorrhage (MOH), as each patient may need a different pattern of transfusion support. In this background, it is prudent to understand the current prevalent practices and devise preparatory strategies for managing blood requirements during such scenarios. This study helps us know the pattern and type of blood components given to patients with MOHs. METHODOLOGY: This prospective cross-sectional study was conducted on patients with a MOH admitted to a single center at a tertiary care teaching hospital in Puducherry between January 2020 and October 2021...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274968/a-case-report-and-review-of-literature-on-the-role-of-automated-red-cell-exchange-in-managing-sickle-cell-crisis-in-india
#14
Vinu Rajendran, Archisha Kalra, Ashna George, Deepika Chenna, Ganesh Mohan, Shamee Shastry
Red cell exchanges (RCE) help in the treatment of complications of sickle cell anemia (SCA) by reducing the viscosity of blood and improving the oxygen-carrying capacity. We present a case of sickle cell crisis (SCC) managed with automated RCE and also reviewed the literature to assess the utilization and clinical efficiency of this therapy in India. A 19-year-old gentleman diagnosed with SCA presented with acute chest syndrome. Hemoglobin (Hb) was 8.8 g%, hematocrit (HCT) was 24%, and HbS was 90%. As there was worsening of symptoms with conventional management, the patient underwent two procedures of automated RCE...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274967/correlation-of-various-methods-of-hematopoietic-progenitor-cell-estimation-with-standard-flowcytometric-cd34-enumeration
#15
JOURNAL ARTICLE
Aseem Kumar Tiwari, Aanchal Sunil Luthra, Dinesh Arora, Swati Pabbi Mehta, Geet Aggarwal, Nitin Sood, Satyaprakash Yadav, Anand Prakash Upadhyay
BACKGROUND AND OBJECTIVES: Enumeration of hematopoietic progenitor cell (HPC) is vital to decide the time to initiate harvest (TTIH) and adequacy of harvest dose (AOHD). Standard of care used for HPC enumeration is flowcytometric CD34+ enumeration, but it is expensive, time-consuming and requires skilled staff to perform the test. Alternatively, HPC-count by advanced automated cell analyzer is cheaper, quicker, and easy-to-perform test. Our objective was to find a correlation of HPC count with CD34+ enumeration in leukapheresis...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274966/autologous-blood-transfusion-in-a-neurosurgical-patient-with-multiple-alloantibodies
#16
Angel Mary Sam, Amita Radhakrishnan Nair, Debasish Gupta
There are many challenges to obtain antigen-negative, crossmatch compatible blood for a patient with multiple alloantibodies. We present a case report of a 31-year-old female patient with a recurrent pontine cavernoma who was to undergo a neurosurgical procedure. We identified alloantibodies anti-Fya and anti-c in her blood sample. To meet her intraoperative blood requirement, we attempted with autologous blood transfusion using both predeposit autologous donation and acute normovolemic hemodilution. Autologous blood alone was sufficient despite anticipating surgical blood loss and a postoperative surgical site infection...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274965/effect-of-donor-parameters-and-cell-separators-on-yield-of-apheresis-platelet-and-their-impact-on-corrected-count-increment-in-aplastic-anemia-patients
#17
JOURNAL ARTICLE
Anubha Srivastava, Brijesh Kumar Yadav, Indranil Das, Rahul Katharia, Rajendra K Chaudhary, Pallavi Rani, Atul Priyadarshi
BACKGROUND: The new cell separators make it simple to collect single donor platelets (SDP), although the platelet yield may vary depending on the cell separator used and donor-related clinical and laboratory variables. AIMS: This study aims to study the factors affecting SDP yield and corrected count increment (CCI). MATERIALS AND METHODS: This retrospective study was carried out at a tertiary care facility in northern India, over 4 years (May 2017-April 2020), data were retrieved and analyzed...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274964/red-cell-alloimmunization-and-associated-risk-factors-in-multiply-transfused-thalassemia-patients-a-prospective-cohort-study-conducted-at-a-tertiary-care-center-in-northern-india
#18
JOURNAL ARTICLE
Brijesh Kumar Yadav, Rajendra K Chaudhary, Priti Elhence, Shubha Rao Phadke, Kausik Mandal, Deepti Saxena, Amita Moirangthem
BACKGROUND: One of the complications of chronic transfusions in thalassemia is the development of red cell alloimmunization. AIMS: The aim of the study was to determine the frequency, specificity of red cell alloantibodies, and factors influencing alloimmunization in multiply transfused thalassemia patients. MATERIALS AND METHODS: The study was carried out prospectively on beta-thalassemia patients over 10 months. Plasma samples were used for antibody screening and identification using the column agglutination technique...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274963/quality-assessment-of-platelet-concentrates-prepared-by-platelet-rich-plasma-buffy-coat-and-apheresis-methods-in-a-tertiary-care-hospital-in-south-india-a-cross-sectional-study
#19
JOURNAL ARTICLE
Esha Toora, Rajendra G Kulkarni, Prabhu Manivannan, Apurba Sankar Sastry, Abhishekh Basavarajegowda, Dibyajyoti Sahoo
INTRODUCTION: In blood banking and transfusion medicine, it is of paramount importance to improve transfusion safety and provide a higher quality of product to maximize the therapeutic outcomes and minimize the risk of developing transfusion-associated complications for patients receiving a blood transfusion. MATERIALS AND METHODS: This was a cross-sectional study conducted at the department of transfusion medicine in a tertiary care hospital of South India from February 2019 to December 2020...
2023: Asian Journal of Transfusion Science
https://read.qxmd.com/read/38274962/an-autoantibody-to-rh-ce-protein-causing-positive-direct-antiglobulin-test-in-a-healthy-blood-donor
#20
Yesha Nirmal Parikh, Mayuri M Vekariya, Vasant Kaushik Gondaliya, Manisha M Rajapara, Sanmukh Ratilal Joshi
A positive direct antiglobulin test (DAT) is of diagnostic feature for the patient with autoimmune hemolytic anemia (AIHA). However, on rare occasions, for obscure reasons, it is found among healthy blood donors. The present report is aimed to elucidate serological and immunological characteristics of such autoantibody in a healthy donor aged 62 years found with positive DAT. There was no history of Leishmaniasis, nor having a significant illness. His red blood cells (RBCs) showed incompatible cross-match results with every recipient tested in the antiglobulin phase...
2023: Asian Journal of Transfusion Science
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