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Journal of Addiction Medicine

Itai Danovitch, Alexander Joseph Steiner, Anna Kazdan, Matthew Goldenberg, Margaret Haglund, James Mirocha, Katherine Collison, Brigitte Vanle, Jonathan Dang, Waguih William IsHak
OBJECTIVE: Alcohol use disorders (AUDs) are common among persons with major depressive disorder (MDD) and have an adverse impact on course of illness and patient outcomes. The aim of this study was to examine whether AUD adversely impacted patient-centered outcomes in a sample of research subjects evaluated as part of a large clinical trial for depression. The outcomes of interest to this post hoc analysis are quality of life (QOL), functioning, and depressive symptom severity. METHODS: We analyzed 2280 adult MDD outpatient research subjects using data from the Sequenced Treatment Alternatives to Relieve Depression trial...
October 18, 2016: Journal of Addiction Medicine
Daniel Fuster, Arantza Sanvisens, Ferran Bolao, Paola Zuluaga, Inmaculada Rivas, Magi Farré, Jordi Tor, Robert Muga
BACKGROUND: The health burden of cannabis use in patients with other substance dependencies is not fully understood. OBJECTIVE: To assess the impact of cannabis use as secondary drug on mortality of patients with other major substance use disorders. PARTICIPANTS: Patients with opiate, cocaine, or alcohol dependence admitted to detoxification from 2001 to 2010 at a teaching hospital in Badalona, Spain. MAIN MEASUREMENTS: Sociodemographic characteristics, drug use, medical comorbidities, and urine drug screens were obtained at admission...
October 6, 2016: Journal of Addiction Medicine
Joni Bing Fei Teoh, Anne Yee, Mahmoud Danaee, Chong Guan Ng, Ahmad Hatim Bin Sulaiman
OBJECTIVES: Erectile dysfunction (ED) is a problem commonly encountered by patients on methadone maintenance therapy (MMT). This study aimed to assess the prevalence of ED among this group of patients along with its risk factors and association with quality of life (QOL). METHODS: Male patients on MMT in a tertiary hospital in Malaysia were included in the study. A total of 134 patients with sexual partners were assessed for ED using the International Index of Erectile Function...
October 6, 2016: Journal of Addiction Medicine
Curtis Bone, Lilian Gelberg, Mani Vahidi, Barbara Leake, Julia Yacenda-Murphy, Ronald M Andersen
OBJECTIVE: The Affordable Care Act encourages integration of behavioral health into primary care. We aim to estimate the level of under-reporting of drug use in federally qualified health centers (FQHCs) among self-reported risky drug users. METHODS: Adult patients in the waiting rooms of 4 FQHCs who self-reported risky drug use on the screening instrument World Health Organization's Alcohol, Smoking and Substance Involvement Screening Test (score 4-26), who participated in the "Quit Using Drugs Intervention Trial," submitted urine samples for drug testing...
October 6, 2016: Journal of Addiction Medicine
Teerayuth Rungnirundorn, Viroj Verachai, Joel Gelernter, Robert T Malison, Rasmon Kalayasiri
BACKGROUND AND OBJECTIVE: Males and females who use methamphetamine (MA) differ in sociodemographics, MA diagnoses, comorbidities, and brain activity. The objective of this study was to investigate sex differences in the characteristics of MA use and dependence in patients at a Thai substance treatment center. METHODS: Demographic, MA use, and diagnostic data for 782 MA users were obtained by using the Semi-Structured Assessment for Drug Dependence and Alcoholism-Thai version...
September 19, 2016: Journal of Addiction Medicine
Kaina Zhou, Hengxin Li, Xiaoli Wei, Xiaomei Li, Guihua Zhuang
OBJECTIVES: To identify medication adherence and its influencing factors among patients of 14 methadone maintenance treatment (MMT) clinics in Xi'an, China. METHODS: Data were obtained from the National AIDS Information System-Community Methadone Maintenance Treatment. All patients registered in the system were not permitted to take methadone at home without professionals' supervision. Medication adherence was assessed using categorical (ie, dropout or retained) and continuous (ie, treatment time, methadone use time, and percentage of methadone use days) variables...
September 19, 2016: Journal of Addiction Medicine
Adam Rzetelny, Barbara Zeller, Nicholas Miller, Kenneth L Kirsh, Steven D Passik
Clinical drug monitoring has an increasingly important role in the treatment of substance use disorders. Through semistructured interviews, we asked substance-use counselors about the clinical impact of drug tests on patients' treatment planning and outcomes. This study was conducted around the time of a facility-wide switch to a laboratory utilizing definitive liquid chromatography with tandem mass spectrometry from a laboratory that had utilized the less-sensitive, presumptive immunoassay-based drug-testing methodology...
September 19, 2016: Journal of Addiction Medicine
Amber L Bahorik, Derek D Satre, Andrea H Kline-Simon, Constance M Weisner, Cynthia I Campbell
OBJECTIVES: We examined prevalence of major medical conditions and extent of disease burden among patients with and without substance use disorders (SUDs) in an integrated health care system serving 3.8 million members. METHODS: Medical conditions and SUDs were extracted from electronic health records in 2010. Patients with SUDs (n = 45,461; alcohol, amphetamine, barbiturate, cocaine, hallucinogen, and opioid) and demographically matched patients without SUDs (n = 45,461) were compared on the prevalence of 19 major medical conditions...
September 8, 2016: Journal of Addiction Medicine
Natasha Simonovska, Beti Zafirova-Ivanovska, Aleksandra Babulovska, Zanina Pereska, Irena Jurukov, Liljana Trenchevska-Siljanovska
OBJECTIVE: The incidence of autoantibodies may be associated with the duration of drug use. In this study, we assessed the association between the duration of heroin dependence and various humoral immunologic indicators, including IgA, IgG, IgM, complement component 3, complement component 4, rheumatoid factor, anti-β2-glycoprotein 1 (IgA, IgG, IgM), antinuclear antibody, circulating immune complexes, and cryoglobulins. METHODS: A total of 363 patients with heroin dependence were enrolled in this cross-sectional and prospective study over a 3...
September 8, 2016: Journal of Addiction Medicine
Julie R Gaither, Joseph L Goulet, William C Becker, Stephen Crystal, E Jennifer Edelman, Kirsha Gordon, Robert D Kerns, David Rimland, Melissa Skanderson, Amy C Justice, David A Fiellin
OBJECTIVE: Patients with substance use disorders (SUDs) prescribed long-term opioid therapy (LtOT) are at risk for overdose and mortality. Prior research has shown that receipt of LtOT in accordance with clinical practice guidelines has the potential to mitigate these outcomes. Our objective was to determine whether the presence of a SUD modifies the association between guideline-concordant care and 1-year all-cause mortality among patients receiving LtOT for pain. METHODS: Among HIV+ and HIV- patients initiating LtOT (≥90 days opioids) between 2000 and 2010 as part of the Veterans Aging Cohort Study, we used time-updated Cox regression and propensity-score matching to examine-stratified by SUD status-the association between 1-year all-cause mortality and 3 quality indicators derived from national opioid-prescribing guidelines...
September 8, 2016: Journal of Addiction Medicine
Matthew C Waesche, Charles Brendan Clark, Karen L Cropsey
BACKGROUND: To determine if thwarted belongingness in combination with frequent alcohol use increased suicidal and homicidal ideation when known predictors were controlled for (eg, depressive disorders, anxiety disorders, drug use, race, sex, age, and employment status). METHOD: This study utilized an archival database. Participants were 574 individuals at an outpatient substance abuse treatment facility who were under community corrections supervision. The average age was 34...
September 7, 2016: Journal of Addiction Medicine
Michael J Mason, Gregory Golladay, William Jiranek, Brian Cameron, Joel J Silverman, Nikola M Zaharakis, Paul Plonski
BACKGROUND: The nonmedical use of prescription medication among US adults is a growing public health problem. Healthcare providers should proactively address this problem in outpatient encounters. OBJECTIVE: We sought to understand the interactive effects among prescription drugs, pain, and psychiatric symptoms among adult outpatients to build an empirical foundation for comprehensive screening. METHODS: We screened 625 adult neurosurgery and orthopedic patients at a suburban satellite clinic of an urban academic medical center...
September 7, 2016: Journal of Addiction Medicine
He Zhu, Li-Tzy Wu
OBJECTIVES: To examine trends and correlates of cannabis-involved emergency department (ED) visits in the United States from 2004 to 2011. METHODS: Data were obtained from the 2004 to 2011 Drug Abuse Warning Network. We analyzed trend in cannabis-involved ED visits for persons aged ≥12 years and stratified by type of cannabis involvement (cannabis-only, cannabis-polydrug). We used logistic regressions to determine correlates of cannabis-involved hospitalization versus cannabis-involved ED visits only...
August 29, 2016: Journal of Addiction Medicine
Traci R Rieckmann, Amanda J Abraham, Brian E Bride
INTRODUCTION: Despite considerable empirical evidence that psychosocial interventions improve addiction treatment outcomes across populations, implementation remains problematic. A small body of research points to the importance of research network participation as a facilitator of implementation; however, studies examined limited numbers of evidence-based practices. To address this gap, the present study examined factors impacting implementation of motivational interviewing (MI). METHODS: This study used data from a national sample of privately funded treatment programs (n = 345) and programs participating in the National Drug Abuse Treatment Clinical Trials Network (CTN) (n = 156)...
August 24, 2016: Journal of Addiction Medicine
Tae Woo Park, Lewei Allison Lin, Avinash Hosanagar, Amanda Kogowski, Katie Paige, Amy S B Bohnert
Overdoses involving opioid analgesics represent a significant public health problem in the United States. We reviewed the literature on risk factors for overdose, with a focus on studies that examine clinical populations of patients receiving opioids for pain and potential risk factors for overdose in these populations. A structured review resulted in 15 articles published between 2007 and 2015 that examined risk factors for fatal and nonfatal overdose in patients receiving opioid analgesics. Opioid dosage was the factor most consistently analyzed and also associated with increased risk of overdose...
August 11, 2016: Journal of Addiction Medicine
James W Price
INTRODUCTION: If employee drug use plays a significant part in the incidence of workplace accidents, one would anticipate the positivity rates of postaccident drug tests to be higher than the positivity rates for random tests. Past studies examined the difference of a dichotomous outcome between 2 groups. Dichotomous (positive or negative) categorization may have been a source of systemic error, which minimized the difference between random and postaccident groups. METHODS: This is a study exploring the difference of urine drug concentrations between random and postaccident groups...
August 11, 2016: Journal of Addiction Medicine
Lewei Allison Lin, Avinash Hosanagar, Tae Woo Park, Amy S B Bohnert
The present clinical case discussion focuses on a patient with comorbid substance use disorder (SUD) and chronic pain, who experienced an overdose of heroin. The case illustrates the complex array of risk factors that contribute to overdose risk, discusses the use of naloxone, and highlights the need for further risk mitigation interventions in patients at risk for overdose.
August 11, 2016: Journal of Addiction Medicine
Emily E Hartwell, Nathasha R Moallem, Kelly E Courtney, Suzette Glasner-Edwards, Lara A Ray
OBJECTIVES: Methamphetamine (MA) users often have substantial psychiatric comorbidities, with nearly a third reporting lifetime mood disorders and over a quarter reporting lifetime anxiety disorders. Female MA users are more likely to endorse depression and anxiety symptoms compared with men. Craving has been related to mood/anxiety symptoms in MA users. To extend the literature on sex differences in MA use disorder, the present study examines the role of sex as a moderator of the relationship between mood/anxiety symptoms and MA craving...
August 8, 2016: Journal of Addiction Medicine
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No abstract text is available yet for this article.
September 2016: Journal of Addiction Medicine
Marija Zeremski, Clewert Sylvester, Andrew H Talal
No abstract text is available yet for this article.
September 2016: Journal of Addiction Medicine
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