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Journal of Addiction Medicine

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https://www.readbyqxmd.com/read/28166085/when-the-laughing-stops-subacute-combined-spinal-cord-degeneration-caused-by-laughing-gas-use
#1
Annemiek Buizert, Ruby Sharma, Hille Koppen
Here we describe a case of subacute combined spinal cord degeneration caused by nitrous oxide (N2O, laughing gas) use. Because of its euphoric effects, the use of N2O has become increasingly popular in recent years. Unfortunately, the use of N2O leads to inactivation of vitamin B12. Vitamin B12 plays an essential role in the synthesis and maintenance of myelin, a fatty substance that surrounds nerve cells and is crucial for their functioning. Deficiency of vitamin B12 could typically result in degeneration of posterior and lateral columns of the spinal cord...
February 3, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28166084/unexpected-complication-of-cocaine-associated-anti-neutrophil-cytoplasmic-antibody-vasculitis-related-to-persistent-in-hospital-cocaine-use
#2
Travis D Olives, Rebecca L Kornas, Russell Fujisawa, Jon B Cole
INTRODUCTION: Levamisole-adulterated cocaine has been implicated in anti-neutrophil cytoplasmic antibody (ANCA) vasculitis. We present a case of spontaneous intraperitoneal hemorrhage, an unexpectedly severe complication of cocaine-related ANCA vasculitis, developing late during hospitalization. CASE REPORT: An adult male with a history of hepatitis C, distant cocaine use, and limited health care presented to a local emergency department (ED) with volume overload, renal failure, hyperkalemia and non-anion gap metabolic acidosis...
February 3, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28157829/how-should-remote-clinical-monitoring-be-used-to-treat-alcohol-use-disorders-initial-findings-from-an-expert-round-table-discussion
#3
Alan Gordon, Adi Jaffe, A Thomas McLellan, Gary Richardson, Gregory Skipper, Michel Sucher, Carlos F Tirado, Harold C Urschel
Scientific evidence combined with new health insurance coverage now enable a chronic illness management approach to the treatment of alcohol use disorders (AUDs), including regular monitoring of blood alcohol content (BAC), as a useful indicator of disease control. Recent technical advances now permit many different types of remote, real-time monitoring of BAC. However, there is no body of research to empirically guide clinicians in how to maximize the clinical potential of remote BAC monitoring.As an initial step in guiding and supporting such research, the manufacturer of one remote BAC monitoring system sponsored a group of experienced clinicians and clinical researchers to discuss 8 issues that generally affect remote, clinical BAC monitoring of "adults in outpatient AUD treatment...
February 2, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28125446/inpatient-gamma-hydroxybutyrate-detoxification-a-case-report-describing-day-to-day-therapeutic-management
#4
Louis von Theobald, Morgane Rousselet, Jennyfer Cholet, Hélène Debar, David Boels, Caroline Victorri-Vigneau, Marie Grall-Bronnec
BACKGROUND: Gamma-hydroxybutyrate (GHB) is a synthetic drug increasingly used by consumers of psychoactive substances. The sought after psychoactive effects of GHB have resulted in an increase in recreational use in Europe. GHB is considered to have a high dependence potential, and abrupt discontinuation after long-term use can result in a severe withdrawal syndrome. Despite a large number of publications related to GHB withdrawal and detoxification, to date, no evidence-based protocol or consensual international therapeutic guidelines are available (over and above the administration of benzodiazepines)...
January 25, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28107210/treatment-outcome-comparison-between-telepsychiatry-and-face-to-face-buprenorphine-medication-assisted-treatment-for-opioid-use-disorder-a-2-year-retrospective-data-analysis
#5
Wanhong Zheng, Michael Nickasch, Laura Lander, Sijin Wen, Minchan Xiao, Patrick Marshalek, Ebony Dix, Carl Sullivan
OBJECTIVES: To retrospectively review clinic records to assess the difference between face-to-face and telepsychiatry buprenorphine medication-assisted treatment (MAT) programs for the treatment of opioid use disorder on 3 outcomes: additional substance use, average time to achieve 30 and 90 consecutive days of abstinence, and treatment retention rates at 90 and 365 days. METHODS: Medical records of patients (N = 100) who were participating in telepsychiatry and in face-to-face group-based outpatient buprenorphine MAT programs were reviewed and assessed using descriptive statistical analysis...
January 19, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28079573/medically-assisted-withdrawal-detoxification-considering-the-mother-infant-dyad
#6
Hendrée E Jones, Mishka Terplan, Marjorie Meyer
Recommendations for opioid agonist pharmacotherapy and against medically assisted withdrawal were based upon early reports that associated withdrawal with maternal relapse and fetal demise. Data from recent case series have called these recommendations into question. Although these data do not support an association between medically assisted withdrawal and fetal demise, relapse remains a significant clinical concern with reported rates ranging from 17% to 96% (average 48%). Given the high loss to follow-up in these studies, the actual relapse rate is likely even greater...
January 11, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28079572/concurrent-treatment-of-ptsd-and-substance-use-disorders-using-prolonged-exposure-cope-a-pilot-study-in-alcohol-dependent-women
#7
Anna Persson, Sudie E Back, Therese K Killeen, Kathleen T Brady, Melanie L Schwandt, Markus Heilig, Åsa Magnusson
OBJECTIVES: Posttraumatic stress disorder (PTSD) and substance use disorders are highly comorbid. Effective treatments are largely lacking. This pilot study evaluated the safety and feasibility of a novel intervention, Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE), in preparation for a randomized controlled trial. METHODS: Twenty-two treatment-seeking women with current DSM-IV-TR PTSD and alcohol dependence (AD) were recruited...
January 11, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28067758/pain-interference-psychopathology-and-general-medical-conditions-among-black-and-white-adults-in-the-us-general-population
#8
Declan T Barry, Corey Pilver Glenn, Rani A Hoff, Marc N Potenza
OBJECTIVES: To assess how race might moderate relationships between pain interference and psychopathology, and general medical conditions among a nationally representative sample of black and white adults. METHODS: Chi-square tests and multivariable logistic regression analyses were performed on data from the National Epidemiologic Survey on Alcohol and Related Conditions on 32,474 adult respondents (25% black, 75% white), who were categorized according to 1 of 3 levels of pain interference (ie, no/low, moderate, or severe)...
January 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28067757/family-medicine-physicians-with-substance-use-disorder-a-5-year-outcome-study
#9
John S Rose, Michael D Campbell, Peter Yellowlees, Gregory E Skipper, Robert L DuPont
OBJECTIVES: There is little published evidence on how well family medicine physicians (FMPs) with substance use disorder (SUD) perform in Physician Health Programs (PHPs). We examined outcomes for FMP compared with non-FMP physicians. METHODS: This study utilized data from a 5-year, longitudinal, cohort study involving 904 physicians with diagnoses of SUD consecutively admitted to one of 16 state PHPs between 1995 and 2001. We compared 175 FMPs to 687 other physicians...
January 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28067756/alcohol-use-disorders-in-argentinian-girls-and-women-12-months-before-delivery-comparison-of-dsm-iv-dsm-5-and-icd-10-diagnostic-criteria
#10
Mariana Beatriz López, Karina Conde, Mariana Cremonte
BACKGROUND: The evidence of important problems related to prenatal alcohol exposure has faced researchers with the problem of understanding and screening alcohol use in this population. Although any alcohol use should be considered risky during pregnancy, identifying alcohol-drinking problems (ADPs) could be especially important because women with ADPs could not benefit from a simple advice of abstinence and because their offsprings are subjected to a higher risk of problems related with prenatal alcohol exposure...
January 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28060223/coronary-plaque-progression-and-regression-in-asymptomatic-african-american-chronic-cocaine-users-with-obstructive-coronary-stenoses-a-preliminary-study
#11
Veit Sandfort, David A Bluemke, Jose Vargas, Jeffrey A Brinker, Gary Gerstenblith, Thomas Kickler, Gang Zheng, Ji Li, Shaoguang Chen, Hong Lai, Elliot K Fishman, Shenghan Lai
OBJECTIVE: Although rapid progression of coronary atherosclerosis was observed in chronic cocaine users, it is unknown whether reduced cocaine use retards the progression of atherosclerosis. We investigated whether reduced cocaine use over a 12-month period was associated with coronary plaque regression in cocaine users. METHODS: Fifteen African American chronic cocaine users with previously coronary computed tomography angiography (CCTA)-confirmed >50% coronary stenosis in Baltimore, Maryland, were enrolled in a study to investigate whether reduced cocaine use is associated with changes in coronary plaque burden over a 12-month period of cash-based incentive intervention, which was implemented to systematically reinforce cocaine abstinence...
January 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/27926589/dystonia-in-methylphenidate-withdrawal-a-case-report
#12
Lara Grau-López, Constanza Daigre, Nestor Mercado, Miquel Casas, Carlos Roncero
Few studies have described movement disorders as withdrawal symptoms during psychostimulant detoxification. Although dystonia has been reported as an uncommon adverse effect of methylphenidate treatment, it has not been described in the context of methylphenidate withdrawal. We report a case of dystonia as the main withdrawal symptom in a methylphenidate-dependent adult participating in an inpatient methylphenidate detoxification program. Although movement disorders such as dystonia are very rare adverse effects of methylphenidate withdrawal, practitioners need to be alert to this risk in order to initiate appropriate treatment...
December 6, 2016: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28157832/preliminary-results-and-publication-impact-of-a-dedicated-addiction-clinician-scientist-research-fellowship
#13
Jan Klimas, Elaine Fernandes, Kora deBeck, Kanna Hayashi, M-J Milloy, Thomas Kerr, Walter Cullen, Evan Wood
No abstract text is available yet for this article.
January 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28027191/intentional-intra-arterial-injection-of-heroin-a-case-report
#14
Joji Suzuki, Erin S Valenti
Intravenous injection of drugs is associated with a host of medical complications, notably soft-tissue infections. On the contrary, intra-arterial injections of drugs have also been reported, largely restricted to inadvertent injections. Here we describe a patient who engaged in repeated intra-arterial injections of heroin when she exhausted most of her venous access, and presented acutely with a radial artery occlusion requiring thrombolytic therapy. Clinicians should have a high index of suspicion for intra-arterial injection in injection drug users who present with limb pain, ischemia, and motor/sensory deficits...
January 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/27898498/intention-to-drive-after-drinking-among-medical-students-contributions-of-the-protection-motivation-theory
#15
Ricardo Abrantes Amaral, André Malbergier, Danielle Ruiz Lima, Verena Castellani Vitor Santos, Clarice Gorenstein, Arthur Guerra de Andrade
OBJECTIVE: The aim of this study was to investigate whether cognitive variables proposed by the protection motivation theory (PMT) were predictive of occasional and frequent intention to drive after drinking in medical students. METHODS: One hundred fifty-five students attending preclinical years at a Medical School in São Paulo, Brazil, participated in the study. They were asked about their last month substance use, history of drinking and driving, including driving after binge drinking, and risk perceptions based on a self-report questionnaire with statements about protection motivation, threat, and coping appraisals from the PMT model...
January 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/27898497/medications-for-addiction-treatment-changing-language-to-improve-care
#16
Sarah E Wakeman
The term medication-assisted treatment has been widely adopted in reference to the use of opioid agonist therapy. Although it is arguably better than the older terms of replacement or substitution therapy, medication-assisted treatment implies that medications are a corollary to whatever the main part of treatment is. No other medication for other health conditions is referred to this way. It has finally been recognized that to improve care and reduce stigma, we must use medically accurate and person-first language, describing those with the disease of addiction as people with substance use disorder...
January 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/27898496/distinctive-trajectories-of-opioid-use-over-an-extended-follow-up-of-patients-in-a-multisite-trial-on-buprenorphine%C3%A2-%C3%A2-naloxone-and-methadone
#17
Yih-Ing Hser, David Huang, Andrew J Saxon, George Woody, Andrew L Moskowitz, Abigail G Matthews, Walter Ling
OBJECTIVES: Uncovering heterogeneities in longitudinal patterns (trajectories) of opioid use among individuals with opioid use disorder can increase our understanding of disease progression and treatment responses to improve care. The present study aims to identify distinctive opioid use trajectories and factors associated with these patterns among participants randomized to treatment with methadone (MET) or buprenorphine + naloxone (BUP). METHODS: Growth mixture modeling was applied to identify distinctive opioid use trajectories among 795 opioid users after their enrollment in a multisite trial during 2006 to 2009, with follow-up interviews conducted during 2011 to 2014...
January 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/27898495/frequency-of-e-cigarette-use-health-status-and-risk-and-protective-health-behaviors-in-adolescents
#18
Michael S Dunbar, Joan S Tucker, Brett A Ewing, Eric R Pedersen, Jeremy N V Miles, Regina A Shih, Elizabeth J D'Amico
OBJECTIVES: E-cigarettes (ECs) are increasingly popular among adolescents, who perceive them as "safer" than cigarettes. Although research has examined risk factors for adolescent EC use, little is known about how EC use correlates with health status and protective health behaviors. METHODS: In all, 2488 adolescents (mean age = 17.31 years, SD = 0.67; 46% male) completed a survey on EC and cigarette use, physical and mental health, physical activity, diet, sleep, and alcohol and other drug (AOD) use...
January 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/27775955/depression-anxiety-and-stress-among-people-with-chronic-hepatitis-c-virus-infection-and-a-history-of-injecting-drug-use-in-new-south-wales-australia
#19
Emmanuel Fortier, Maryam Alavi, Julie Bruneau, Michelle Micallef, Jacinta Perram, Sanjeev Sockalingam, Adrian J Dunlop, Annie C Balcomb, Carolyn A Day, Carla Treloar, Nicky Bath, Paul S Haber, Gregory J Dore, Jason Grebely
OBJECTIVE: The aims of this study were to assess symptoms of depression, anxiety, and stress and associated sociodemographic factors among people living with chronic hepatitis C virus (HCV) infection with a history of injecting drug use and to assess the association between symptoms of depression, anxiety, or stress and HCV treatment intent, specialist assessment, or treatment uptake. METHODS: The Enhancing Treatment for Hepatitis C in Opioid Substitution Settings was an observational cohort study evaluating the provision of HCV assessment and treatment among people with chronic HCV and a history of injecting drug use, recruited from 9 community health centers and opioid substitution therapy (OST) clinics (New South Wales, Australia)...
January 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/27763941/analysis-of-patient-reported-outcomes-of-quality-of-life-and-functioning-before-and-after-treatment-of-major-depressive-disorder-comorbid-with-alcohol-use-disorders
#20
Itai Danovitch, Alexander Joseph Steiner, Anna Kazdan, Matthew Goldenberg, Margaret Haglund, James Mirocha, Katherine Collison, Brigitte Vanle, Jonathan Dang, Waguih William IsHak
OBJECTIVE: Alcohol use disorders (AUDs) are common among persons with major depressive disorder (MDD) and have an adverse impact on course of illness and patient outcomes. The aim of this study was to examine whether AUD adversely impacted patient-centered outcomes in a sample of research subjects evaluated as part of a large clinical trial for depression. The outcomes of interest to this post hoc analysis are quality of life (QOL), functioning, and depressive symptom severity. METHODS: We analyzed 2280 adult MDD outpatient research subjects using data from the Sequenced Treatment Alternatives to Relieve Depression trial...
January 2017: Journal of Addiction Medicine
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