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Journal of Addiction Medicine

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https://www.readbyqxmd.com/read/28930773/a-case-of-opioid-overdose-and-subsequent-death-after-medically-supervised-withdrawal-the-problematic-role-of-rapid-tapers-for-opioid-use-disorder
#1
Derek C Chang, Jan Klimas, Evan Wood, Nadia Fairbairn
BACKGROUND: Relapse to opioid use is common after rapid opioid withdrawal. As a result, short-term tapers of opioid agonist/partial agonist medications, such as methadone and buprenorphine/naloxone, are no longer recommended by recent clinical care guidelines for the management of opioid use disorder. Nonetheless, rapid tapers are still commonplace in medically supervised withdrawal settings. CASE SUMMARY: We report a case of an individual with opioid use disorder who was prescribed a rapid buprenorphine/naloxone taper in a medically supervised withdrawal facility and who had a subsequent opioid overdose and death after discharge...
September 19, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28922195/dispositional-mindful-attention-in-relation-to-negative-affect-tobacco-withdrawal-and-expired-carbon-monoxide-on-and-after-quit-day
#2
Daniel J Paulus, Kirsten J Langdon, David W Wetter, Michael J Zvolensky
BACKGROUND: Mindfulness (or "Mindful Attention") has been described as the presence or absence of attention to, and awareness of, what is occurring in the present moment. Among smokers, greater mindfulness is associated with greater effect stability and reduced cue-induced craving. While studies have shown that mindfulness is associated with other smoking-related factors such as reduced withdrawal symptoms using cross-sectional data, relatively little is known about the associations between baseline mindful attention and future abstinence-related effect/withdrawal...
September 15, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28914663/physicians-decision-making-when-implementing-buprenorphine-with-new-patients-conjoint-analyses-of-data-from-a-cohort-of-current-prescribers
#3
Hannah K Knudsen, Michelle R Lofwall, Sharon L Walsh, Jennifer R Havens, Jamie L Studts
OBJECTIVES: Few studies have considered how providers make decisions to prescribe buprenorphine to new patients with opioid use disorder. This study examined the relative importance of patients' clinical, financial, and social characteristics on physicians' decision-making related to willingness to prescribe buprenorphine to new patients and the number of weeks of medication that they are willing to initially prescribe after induction. METHODS: A national sample of 1174 current prescribers was surveyed...
September 13, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28901998/relationships-between-components-of-emotional-intelligence-and-suicidal-behavior-in-alcohol-dependent-patients
#4
Maciej Kopera, Andrzej Jakubczyk, Anna Klimkiewicz, Hubert Suszek, Aleksandra Krasowska, Kirk J Brower, Marcin Wojnar
OBJECTIVES: The importance of investigating various emotional skills in assessment of suicide risk in alcohol-dependent (AD) individuals has recently become the focus of increasing interest. The objective of this study was to explore the relationships between self-reported components of emotional intelligence and lifetime prevalence of suicide attempts in a clinical sample of AD subjects. METHODS: A group of 80 inpatients entering an alcohol treatment program in Warsaw, Poland, was recruited...
September 8, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28885301/perceptions-of-neighborhood-mediate-the-relationship-between-ptsd-symptoms-and-coping-in-a-neighborhood-matched-substance-using-sample
#5
Sara K Hertzel, Jennifer Schroeder, Landhing M Moran, Anika A Alvanzo, William J Kowalczyk, David H Epstein, Kenzie L Preston, Karran A Phillips
OBJECTIVES: People with substance use problems living in neighborhoods with high levels of disorder are disproportionately likely to experience trauma and develop PTSD symptoms. We sought to evaluate the relationships between objective neighborhood disorder, perceptions of neighborhood, and the use of maladaptive coping behaviors among both non-substance-using and substance-using participants with and without PTSD symptoms. METHODS: Participants (255 non-drug users [NDUs], 168 marijuana and/or alcohol users [MAUs], and 273 opioid and/or stimulant users) completed the Addiction Severity Index, PTSD Checklist-Civilian Version, The COPE Inventory, and the Perceived Neighborhood Scale...
September 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28885300/use-of-smoking-cessation-methods-among-patients-receiving-office-based-buprenorphine-maintenance-treatment
#6
Pooja A Shah, Chinazo O Cunningham, Mia T Brisbane, Joseph P DeLuca, Shadi Nahvi
OBJECTIVES: Provision of smoking-cessation treatment is limited in office-based buprenorphine maintenance treatment (BMT) settings. This study describes smoking and smoking-cessation behaviors among patients receiving office-based BMT. METHODS: Cross-sectional study of patients receiving office-based BMT at a community health center in the Bronx, NY. We interviewed patients assessing sociodemographic, and substance use and tobacco use characteristics, including methods used for smoking cessation...
September 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28885299/correlates-of-stigma-severity-among-persons-seeking-opioid-detoxification
#7
Nikki Bozinoff, Bradley J Anderson, Genie L Bailey, Michael D Stein
INTRODUCTION: Among people with opioid use disorder (OUD), stigma is a known barrier to accessing treatment and has negative impacts on physical and mental health. The purpose of this study was to understand the factors associated with self-stigma and perceived stigma severity among people with OUD entering an inpatient detoxification program. METHODS: Between December 2015 and August 2016, consecutive persons seeking inpatient opioid detoxification were asked to complete a survey that included sociodemographic, drug use, treatment variables, an 8-item General Self-Stigma scale, and a 3-item Treatment Stigma scale...
September 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28863009/methadone-and-the-qtc-interval-paucity-of-clinically-significant-factors-in-a-retrospective-cohort
#8
Gavin Bart, Zachary Wyman, Qi Wang, James S Hodges, Rehan Karim, Bradley A Bart
OBJECTIVE: Methadone is associated with prolongation of the electrocardiographic QTc interval. QTc prolongation may be linked to cardiac dysrhythmia and sudden cardiac death. The rate of these events is unknown in methadone-maintained patients. METHODS: This retrospective cohort study of 749 patients with opioid use disorder receiving methadone maintenance therapy through a single safety-net hospital, queried the electronic health record for electrocardiogram results, demographics, methadone dose, and diagnostic codes consistent with cardiac conduction disorder (International Classification of Disease, Ninth Revision [ICD-9] 426) and cardiac dysrhythmia (ICD-9 427)...
August 31, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28858889/prescriptions-written-for-opioid-pain-medication-in-the-veterans-health-administration-between-2000-and-2016
#9
Michael A Grasso, Clare T Grasso, David A Jerrard
OBJECTIVES: The purpose of this study was to identify national opioid pain medication (OPM) prescribing trends within the Veterans Health Administration (VA), and assess the impact of educational campaigns introduced in 2010 and 2013. METHODS: We created a national cohort that documents more than 21 million patient records and 97 million outpatient OPM prescriptions covering a 17-year period. We examined OPM prescriptions in emergency departments, outpatient clinics, and inpatient settings...
August 30, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28858888/acceptability-of-an-opioid-relapse-prevention-text-message-intervention-for-emergency-department-patients
#10
Brian Suffoletto, Joseph Yanta, Ryan Kurtz, Gerald Cochran, Antoine Douaihy, Tammy Chung
OBJECTIVE: To explore whether a text message-based relapse prevention intervention (Preventing and Interrupting Early Relapse [PIER]1) is acceptable to treatment-seeking adults with opioid use disorder (OUD) after Emergency Department (ED) discharge using mixed-methods design. METHODS: Adults seeking care in an urban ED for OUD (n = 20; mean age 22; 55% female; 75% white race) completed a baseline survey, and were invited to enroll in PIER1, which was delivered in 7-day blocks, with the option to re-enroll at the end of each block, up to 4 blocks...
August 30, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28777203/a-review-of-alprazolam-use-misuse-and-withdrawal
#11
Nassima Ait-Daoud, Allan Scott Hamby, Sana Sharma, Derek Blevins
: Alprazolam is one of the most widely prescribed benzodiazepines for the treatment of generalized anxiety disorder and panic disorder. Its clinical use has been a point of contention as most addiction specialists consider it to be highly addictive, given its unique psychodynamic properties which limit its clinical usefulness, whereas many primary care physicians continue to prescribe it for longer periods than recommended. Clinical research data has not fully shed light on its "abuse liability," yet it is one of the most frequently prescribed benzodiazepines...
August 2, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28777202/nitrite-inhalant-use-and-hiv-infection-among-chinese-men-who-have-sex-with-men-in-2-large-cities-in-china
#12
Xiaofang Wang, Yanqi Li, Zunyou Wu, Zhenzhu Tang, Kathleen H Reilly, Quanxing Nong
OBJECTIVE: This study aims to examine the role that nitrite inhalants play in HIV infection and risky sex behaviors among Chinese men who have sex with men (MSM). METHODS: The study consisted of a baseline and a follow-up survey conducted in Beijing and Nanning, China. The baseline study recruited participants through online advertisements and peer referral to complete a questionnaire interview, oral rapid HIV test, and blood HIV and syphilis tests. The follow-up included a questionnaire interview, and optional oral and/or blood HIV testing...
August 2, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28767537/addressing-stigma-in-medication-treatment-of-adolescents-with-opioid-use-disorder
#13
Sarah M Bagley, Scott E Hadland, Brittany L Carney, Richard Saitz
: In September 2016, the American Academic of Pediatrics released a policy statement that adolescents with opioid use disorder should be offered pharmacotherapy with buprenorphine/naloxone, methadone, or naltrexone. In our clinical practice, however, we have encountered the perception among patients, families, and clinicians alike that medications should be used as a last resort. That we should wait until things get worse is a discarded approach. As addiction specialists, it is imperative that we prevent and identify risky use and use disorders, then intervene early and offer timely, evidence-based treatment...
August 1, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28767536/risk-factors-associated-with-skin-and-soft-tissue-infections-among-hospitalized-people-who-inject-drugs
#14
Kristina T Phillips, Bradley J Anderson, Debra S Herman, Jane M Liebschutz, Michael D Stein
OBJECTIVES: Skin and soft tissue infections (SSTIs) are common among people who inject drugs (PWID), and can lead to serious morbidity and costly emergency room and hospital utilization. A range of high-risk injection practices may contribute to these infections. The goal of the current study was to examine risk practices that were associated with SSTIs in a sample of hospitalized PWID. METHODS: PWID (N = 143; 40.6% female) were recruited from inpatient medical units at a large urban hospital and completed a baseline interview that focused on infection risk...
August 1, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28759482/clonidine-increases-the-likelihood-that-abstinence-can-withstand-unstructured-time-in-buprenorphine-maintained-outpatients
#15
William J Kowalczyk, Jeremiah W Bertz, Landhing M Moran, Karran A Phillips, Udi E Ghitza, David H Epstein, Kenzie L Preston
OBJECTIVE: In a clinical trial examining daily clonidine as an adjunct to buprenorphine treatment for opioid dependence, we found that clonidine increased opioid abstinence and decoupled stress from craving. From a personalized-medicine perspective, the next step is to identify people for whom clonidine would be beneficial. To that end, using data from the same clinical trial, we examined the associations of daily-life activities with treatment success. METHODS: Outpatients (N = 118) received clonidine (0...
July 28, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28753139/electronic-cigarette-use-among-counseled-tobacco-users-hospitalized-in-2015
#16
Natacha M De Genna, Thomas Ylioja, Anna E Schulze, Christine Manta, Antoine B Douaihy, Esa M Davis
OBJECTIVES: Few studies have examined the prevalence of electronic cigarette use among the inpatient population regardless of the patients' cessation goals. The objectives of this study were to examine the prevalence of electronic cigarette use among counseled tobacco users admitted to 2 academic hospitals. METHODS: Cross-sectional data of hospitalized adult tobacco users who were admitted between January 1, 2015 and December 31, 2015 and who received bedside tobacco cessation counseling from a tobacco treatment service counselor were examined...
July 27, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28742624/impact-of-a-mandated-change-in-buprenorphine-formulation
#17
Ryan Graddy, Darius A Rastegar
OBJECTIVE: This study examines the impact of an insurance-mandated change in formulation of buprenorphine/naloxone (BNX) for patients with opioid use disorder treated in a primary care clinic. METHODS: A retrospective cohort study was conducted to determine the proportion of patients who were switched back to the previous BNX formulation and rates of aberrant urine drug tests for the 3 months before and 3 months after a mandated change in BNX from the sublingual film to the rapidly dissolving tablet (BNX-RDT)...
July 24, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28731863/screening-adolescents-for-alcohol-use-tracking-practice-trends-of-massachusetts-pediatricians
#18
Sharon Levy, Rosemary E Ziemnik, Sion K Harris, Lily Rabinow, Louise Breen, Christina Fluet, Heather Strother, John H Straus
OBJECTIVES: Substance use screening is a recommended component of routine healthcare for adolescents. A 2008 survey of Massachusetts primary care physicians found high rates of screening, but low rates of validated tool use, leading to the concern that physicians may be missing substance use-related problems and disorders. In an effort to improve practice, a cross-disciplinary group developed and distributed an adolescent screening, brief intervention, and referral to treatment toolkit in 2009...
July 20, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28796120/synthetic-cannabis-analogues-and-suicidal-behavior-case-report
#19
Pedro Miguel Dos Santos Oliveira, Ana Sofia Félix Morais, Nuno Gonçalo Gomes Fernandes Madeira
INTRODUCTION: Despite growing legal control, a wide range of synthetic cannabis analogues is currently used for recreational purposes, notwithstanding their well adverse outcomes, which appear to be more frequent and more serious than those associated with cannabis use. We present the case report of a patient with paranoid schizophrenia, who attempted suicide by serious bodily harm after a single use of "Shiva Ultra Strong," a compound of several synthetic cannabis analogues. CASE SUMMARY: A 32-year-old male patient with paranoid schizophrenia was brought to the emergency department presenting with a severe self-inflicted wound to the neck which lacerated the right jugular vein and ipsilateral airway, and narrowly missed the carotid bifurcation...
September 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28787300/to-improve-substance-use-disorder-prevention-treatment-and-recovery-engage-the-family
#20
Alicia S Ventura, Sarah M Bagley
: Approximately 21 million people in the United States have a substance use disorder (SUD); the number of family members impacted by a loved one's SUD is exponentially greater. Affected family members of individuals with SUDs are at high risk for developing chronic medical and psychiatric health conditions, are high utilizers of the health care system, and have high health care expenditures. Family members play a central role in the lives of many individuals with SUDs; information given to family members can have a significant impact on persons with addiction and therefore the SUD treatment that an individual might receive...
September 2017: Journal of Addiction Medicine
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