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Journal of Addiction Medicine

Azin Khazaeli, Jason M Jerry, Mohsen Vazirian
: In this article, we describe a middle-aged woman with a history of addiction to opioid medications who eventually became dependent on kratom. Her kratom-related withdrawal symptoms responded to a trial of buprenorphine-naloxone. Subsequently, she was maintained on this medication.
July 4, 2018: Journal of Addiction Medicine
Cora von Hammerstein, Ruben Miranda, Henri-Jean Aubin, Lucia Romo, Yasser Khazaal, Amine Benyamina, Amandine Luquiens
: Despite the major health consequences of problem gambling, such as suicide, over-indebtedness, delinquency, or family problems, there is currently no approved drug available for the treatment of problem gambling. The efficacy of cognitive behavioral therapies (CBTs) has been demonstrated repeatedly. However, some people seem resistant to conventional CBT alone. We present the case of a 59-year-old woman with a gambling disorder, who relapsed, despite a CBT-based intervention, and who then received a combined therapy aiming to enhance self-control: a mindfulness-based therapy and cognitive training targeting inhibition...
July 2, 2018: Journal of Addiction Medicine
Duc Anh Ngo, Nassima Ait-Daoud, Saumitra Rege, Christopher Ding, Lauren Gallion, Christopher Holstege
No abstract text is available yet for this article.
June 28, 2018: Journal of Addiction Medicine
Anupriya Gogne, Shannon Erisman
: Psychotic symptoms may emerge in up to 40% of people who misuse stimulants, with physiological changes in the perinatal period potentially contributing to the development of psychosis. In this report, we discuss the case of a woman presenting with stimulant misuse, psychosis, and obsessive compulsive disorder-like symptoms in the postpartum period. We describe the patient's symptoms at presentation, differential diagnoses, treatment course, and related challenges.
June 26, 2018: Journal of Addiction Medicine
Megan Buresh
INTRODUCTION: Use of the unregulated herbal supplement kratom is on the rise in the United States. We present a case series of 2 patients who developed kratom dependence and withdrawal who were successfully transitioned to buprenorphine-naloxone maintenance. CASE SUMMARY: Two patients using kratom to self-treat chronic pain after prescription opioids were discontinued presenting to our clinic with evidence of kratom dependence and withdrawal. On examination, both patients showed signs of mild opioid withdrawal...
June 25, 2018: Journal of Addiction Medicine
Sean Cowlishaw, Jim McCambridge, David Kessler
INTRODUCTION: There are several brief screening tools for gambling that possess promising psychometric properties, but have uncertain utility in generalist healthcare environments which prioritize prevention and brief interventions. This study describes an examination of the National Opinion Research Centre Diagnostic and Statistical Manual of Mental Disorders Screen for Gambling Problems (NODS-CLiP), in comparison with the Problem Gambling Severity Index (PGSI), when used to operationalize gambling problems across a spectrum of severity...
June 25, 2018: Journal of Addiction Medicine
Sara Ling, Kristin Cleverley, Sarah Brennenstuhl, Kirstin Bindseil
OBJECTIVES: The purpose of this study was to determine the frequency and predictors of patients leaving an inpatient medical withdrawal unit against medical advice (AMA). METHODS: This study used a case-control design to compare patients who were discharged AMA (n = 164) with those who completed treatment (n = 678). Logistic regression analysis was used to determine which variables were independent predictors of patients leaving AMA. RESULTS: We found that being admitted through the emergency department (odds ratio [OR] 3...
June 22, 2018: Journal of Addiction Medicine
Parabhdeep Lail, Nadia Fairbairn
: In this issue of the Journal of Addiction Medicine, 2 studies fill an important gap in knowledge by examining predictors of leaving against medical advice from inpatient withdrawal management settings. The studies identify important risk factors for leaving against medical advice and highlight important areas for inpatient withdrawal management. These include the use of substance specific standardized protocols and initiation of opioid agonist treatment instead of opioid detoxification given harms associated with opioid withdrawal...
June 22, 2018: Journal of Addiction Medicine
Jarratt D Pytell, Darius A Rastegar
OBJECTIVE: To determine if certain patient, clinical, and disease factors are associated with against medical advice (AMA) discharge among patients admitted for treatment of alcohol withdrawal. METHODS: Data from admissions to a dedicated unit for treatment of substance withdrawal were collected over a 6-month period. Patients with AMA and planned discharge were compared with regard to demographics, clinical data, and substance use disorder disease characteristics...
June 22, 2018: Journal of Addiction Medicine
Pierre-François Dancoine, Elodie Gentina
BACKGROUND AND AIMS: This study examines the relationship between social support (from parents and peers) and cigarette use, through the mediating effect of smartphone dependence, among adolescents. STUDY DESIGN: Prospective cohort study. METHODS: A survey, conducted among 472 adolescents (average age = 16.2 years) attending classes in 3 schools in Lille, France, provides the data. The theoretical model features social support (parental and peer) and cigarette use, with smartphone dependence as a mediator, such that the authors simultaneously examine direct (support → cigarette use) and indirect (eg, peer support → smartphone dependence → cigarette use) paths...
June 15, 2018: Journal of Addiction Medicine
Jacqueline Wong, Barry Saver, James M Scanlan, Louis Paul Gianutsos, Yachana Bhakta, James Walsh, Abigail Plawman, David Sapienza, Vania Rudolf
OBJECTIVES: To measure the incidence, onset, duration, and severity of neonatal abstinence syndrome (NAS) in infants born to mothers receiving buprenorphine and to assess the association between buprenorphine dose and NAS outcomes. METHODS: We reviewed charts of all mother-infant pairs maintained on buprenorphine who delivered in our hospital from January 1, 2000 to April 1, 2016. RESULTS: In 89 infants, NAS incidence requiring morphine was 43...
June 13, 2018: Journal of Addiction Medicine
Madeline C Frost, Emily C Williams, Susan Kingston, Caleb J Banta-Green
OBJECTIVES: Opioid use is a growing problem in the United States. Despite existence of effective treatments (eg, opioid agonist medication), most people with opioid use disorder do not receive treatment. Increasing treatment receipt is an essential component of the response to the opioid crisis. We examined factors associated with interest in getting help to reduce or stop substance use among syringe exchange program (SEP) clients who reported using opioids. METHODS: Surveys were administered at 17 SEPs across Washington State during 2015; 436 respondents who reported recent opioid use and not receiving current treatment were eligible for this analysis...
June 7, 2018: Journal of Addiction Medicine
Amber D Seelig, Kara M Bensley, Emily C Williams, Richard F Armenta, Anna C Rivera, Arthur V Peterson, Isabel G Jacobson, Alyson J Littman, Charles Maynard, Jonathan B Bricker, Rudolph P Rull, Edward J Boyko
OBJECTIVES: The aim of this study was to determine whether specific individual posttraumatic stress disorder (PTSD) symptoms or symptom clusters predict cigarette smoking initiation. METHODS: Longitudinal data from the Millennium Cohort Study were used to estimate the relative risk for smoking initiation associated with PTSD symptoms among 2 groups: (1) all individuals who initially indicated they were nonsmokers (n = 44,968, main sample) and (2) a subset of the main sample who screened positive for PTSD (n = 1622)...
June 6, 2018: Journal of Addiction Medicine
Yukiko Washio, Katrina Mark, Mishka Terplan
INTRODUCTION: The current study examined distinct characteristics of yearly trend, sociodemographic, and treatment-related variables of prenatal cannabis use as the primary drug of choice among pregnant women admitted to substance use treatment for the first time. METHODS: The Treatment Episode Data Set-Admission between 1992 and 2015 was used for a cross-sectional study focused on prenatal cannabis use reported at treatment admission. RESULTS: Among pregnant women admitted to substance use treatment for the first time (n = 489,796), 40...
June 5, 2018: Journal of Addiction Medicine
Kara M Bensley, Amber D Seelig, Richard F Armenta, Anna C Rivera, Arthur V Peterson, Isabel G Jacobson, Alyson J Littman, Charles Maynard, Jonathan B Bricker, Edward J Boyko, Rudolph P Rull, Emily C Williams
OBJECTIVES: Posttraumatic stress disorder (PTSD) and unhealthy alcohol use are commonly associated conditions. It is unknown whether specific symptoms of PTSD are associated with subsequent initiation of unhealthy alcohol use. METHODS: Data from the first 3 enrollment panels (n = 151,567) of the longitudinal Millennium Cohort Study of military personnel were analyzed (2001-2012). Complementary log-log models were fit to estimate whether specific PTSD symptoms and symptom clusters were associated with subsequent initiation of 2 domains of unhealthy alcohol use: risky and problem drinking (experience of 1 or more alcohol-related consequences)...
June 4, 2018: Journal of Addiction Medicine
Cristina Crocamo, Francesco Bartoli, Cristina Montomoli, Giuseppe Carrà
OBJECTIVES: Binge drinking (BD) among young people has significant public health implications. Thus, there is the need to target users most at risk. We estimated the discriminative accuracy of an innovative model nested in a recently developed e-Health app (Digital-Alcohol RIsk Alertness Notifying Network for Adolescents and young adults [D-ARIANNA]) for BD in young people, examining its performance to predict short-term BD episodes. METHODS: We consecutively recruited young adults in pubs, discos, or live music events...
May 25, 2018: Journal of Addiction Medicine
Jenna R Cummings, A Janet Tomiyama, Lara A Ray
OBJECTIVE: Ibudilast (IBUD) is a neuroimmune modulator that inhibits phosphodiesterase-4 and -10 and macrophage migration inhibitory factor. A randomized, placebo-control, crossover human laboratory trial advanced IBUD development for alcohol use disorder and found that IBUD reduced tonic levels of alcohol craving. Given the importance of considering medication effects on other appetitive behavior, the present study tested the effect of IBUD (50 mg bid) on food craving. METHOD: The present study was a secondary data analysis of the trial of IBUD in non-treatment seekers with alcohol use disorder (N = 19)...
May 21, 2018: Journal of Addiction Medicine
Alicia Allen, Samantha C Carlson, Tyler A Bosch, Lynn E Eberly, Kola Okuyemi, Uma Nair, Judith S Gordon
OBJECTIVES: While exercise significantly reduces craving for cigarettes, the effect of exercise on self-initiation of quit attempts is less known. Therefore, this randomized pilot study explored the effect of starting an exercise program on self-initiated quit attempts, and also the feasibility and acceptability of a novel exercise intervention, high-intensity interval training (HIIT), as compared with a more traditional continuous aerobic (CA) exercise intervention. METHODS: Participants smoked (≥5 cigarettes/d), were aged 18 to 40 years, and wanted to increase their exercise...
May 14, 2018: Journal of Addiction Medicine
David L Rosenbloom
: Blevins et al describe dysfunction in the referral process for substance use disorders. Their recommended solutions, however, are unlikely to address many of the underlying reasons for the dysfunction they describe.
May 7, 2018: Journal of Addiction Medicine
Claire E Blevins, Nishi Rawat, Michael D Stein
OBJECTIVES: The demand for substance use disorder treatment is increasing, fueled by the opioid epidemic and the Affordable Care Act mandate to treat substance use disorders. The increased demand for treatment, however, is not being met by a corresponding increase in access to or availability of treatment. This report focuses specifically on the treatment referral process, which we have identified as 1 of the key barriers to timely and effective treatment. Difficulties in referral to substance use disorder treatment are examined through the lens of providers who make referrals (ie, referral source) and individuals who work in substance use disorder facilities (ie, referral recipient)...
May 7, 2018: Journal of Addiction Medicine
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