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Journal of Diabetes Science and Technology

Thorsten Vahlsing, Sven Delbeck, Steffen Leonhardt, H Michael Heise
Noninvasive blood glucose assays have been promised for many years and various molecular spectroscopy-based methods of skin are candidates for achieving this goal. Due to the small spectral signatures of the glucose used for direct physical detection, moreover hidden among a largely variable background, broad spectral intervals are usually required to provide the mandatory analytical selectivity, but no such device has so far reached the accuracy that is required for self-monitoring of blood glucose (SMBG)...
September 15, 2018: Journal of Diabetes Science and Technology
Gary H Thorpe
The article by Macleod and coauthors outlines an accuracy study of two blood glucose monitoring systems (BGMSs) against glucose-oxidase- and hexokinase-based assays showing how the reference/comparison method and inappropriate sample comparisons can affect accuracy conclusions. The dangers of independent institutions producing inappropriate conclusions when the methodology used for product regulatory or registration accuracy requirements is not according to best practice are stressed. The authors highlight several important aspects of a multistep accuracy evaluation protocol...
September 15, 2018: Journal of Diabetes Science and Technology
Bithika Thompson
In this article in JDST, Feuerstein-Simon and colleagues examine use of a smartphone app in improving hypoglycemia awareness in type 1 diabetes (T1D). They conclude that their smartphone app, HypoMap™, has the potential to increase hypoglycemia awareness and reduce time spent with hypoglycemia in a cohort of long-standing patients with type 1 diabetes. The underlying assumption is that if patients can identify the precipitating cause, they can recognize symptoms better and potentially change behavior to prevent future hypoglycemic events...
September 12, 2018: Journal of Diabetes Science and Technology
Michelle L Litchman, Dana Lewis, Lesly A Kelly, Perry M Gee
BACKGROUND: Patient-driven innovation in diabetes management has resulted in a group of people with type 1 diabetes who choose to build and share knowledge around a do-it-yourself (DIY) open source artificial pancreas systems (OpenAPS). The purpose of this study was to examine Twitter data to understand how patients, caregivers, and care partners perceive OpenAPS, the personal and emotional ramifications of using OpenAPS, and the influence of OpenAPS on daily life. METHODS: Qualitative netnography was used to analyze #OpenAPS on Twitter over a two-year period...
September 10, 2018: Journal of Diabetes Science and Technology
John B Welsh, Xiaohe Zhang, Sarah A Puhr, Terri Kang Johnson, Tomas C Walker, Andrew K Balo, David Price
BACKGROUND: The perceived value and consistent use of continuous glucose monitoring (CGM) systems depends in part on their accuracy. We assessed the performance of a sixth-generation CGM system (Dexcom G6) in children and adolescents. METHODS: Forty-nine participants (6-17 years of age, mean ± SD of 13.5 ± 3.3 years), all with type 1 diabetes, enrolled and data were available from 37. Each participant wore 1 sensor for up to 10 days and was asked to undergo an in-clinic visit lasting 6-12 hours for frequent blood glucose (BG) sample testing on one of the sensor wear days...
September 10, 2018: Journal of Diabetes Science and Technology
Nestoras Mathioudakis, Rebecca Jeun, Gerald Godwin, Annette Perschke, Swaytha Yalamanchi, Estelle Everett, Peter Greene, Amy Knight, Christina Yuan, Sherita Hill Golden
BACKGROUND: Insulin is one of the highest risk medications used in hospitalized patients. Multiple complex factors must be considered in determining a safe and effective insulin regimen. We sought to develop a computerized clinical decision support (CDS) tool to assist hospital-based clinicians in insulin management. METHODS: Adapting existing clinical practice guidelines for inpatient glucose management, a design team selected, configured, and implemented a CDS tool to guide subcutaneous insulin dosing in non-critically ill hospitalized patients at two academic medical centers that use the EpicCare® electronic medical record (EMR)...
September 10, 2018: Journal of Diabetes Science and Technology
David Kerr, David C Klonoff
In the future artificial intelligence (AI) will have the potential to improve outcomes diabetes care. With the creation of new sensors for physiological monitoring sensors and the introduction of smart insulin pens, novel data relationships based on personal phenotypic and genotypic information will lead to selections of tailored, effective therapies that will transform health care. However, decision-making processes based exclusively on quantitative metrics that ignore qualitative factors could create a quantitative fallacy...
September 5, 2018: Journal of Diabetes Science and Technology
Angela L Magdaleno, Gretchen A Perilli, Marc A Vengrove
BACKGROUND: The primary objective was to determine if exposure to radiation has an effect on insulin pump function. METHOD: Four donated insulin pumps were filled with saline and set to identical program modes. They were attached together with a dosimeter and exposed to repeat CT scans. RESULTS: Insulin Pump 1 experienced a "Prime" alarm and a darkened screen during CT scan radiation exposure; this pump was removed from further radiation exposure after 6 CT scans...
September 3, 2018: Journal of Diabetes Science and Technology
Goran Petrovski, Fawziya Al Khalaf, Khalid Hussain, Judith Campbell, Ahmed El Awwa
No abstract text is available yet for this article.
September 3, 2018: Journal of Diabetes Science and Technology
Jothydev Kesavadev, Pradeep Babu Sadasivan Pillai, Arun Shankar, Rohit S Warrier, Lakshmy Ramachandran, Sunitha Jothydev, Gopika Krishnan
No abstract text is available yet for this article.
August 29, 2018: Journal of Diabetes Science and Technology
Timothy L Barnes, Sara Lee, Nels Thompson, Krista Mullen, Paul Chatterton, Laura Gandrud
No abstract text is available yet for this article.
August 23, 2018: Journal of Diabetes Science and Technology
Lutz Heinemann, Delia Waldenmaier, Bernd Kulzer, Ralph Ziegler, Barry Ginsberg, Guido Freckmann
Insulin pumps are used by a steadily increasing number of patients with diabetes. Avoiding certain disadvantages of conventional pumps (ie, the insulin infusion set) might make pump therapy even more attractive. Patch pumps are usually attached by means of an adhesive layer to the skin and have several additional advantages (smaller, more discrete, easier to use, and cheaper than conventional insulin pumps). This review provides a general overview of patch pumps, the technologies used, basic clinical requirements, why a number of developments failed, which clinical studies are needed to provide sufficient evidence for their usage, which costs are associated, what the patient preferences are (which might differ between certain patient groups), and what is the future of patch pumps (ie, artificial pancreas systems)...
August 22, 2018: Journal of Diabetes Science and Technology
Molly L Tanenbaum, Rebecca N Adams, Esti Iturralde, Sarah J Hanes, Regan C Barley, Diana Naranjo, Korey K Hood
BACKGROUND: Diabetes devices such as insulin pumps and continuous glucose monitoring (CGM) are associated with improved health and quality of life in adults with type 1 diabetes (T1D). However, uptake remains low. The aim of this study was to develop different "personas" of adults with T1D in relation to readiness to adopt new diabetes technology. METHODS: Participants were 1498 T1D Exchange participants who completed surveys on barriers to uptake, technology attitudes, and other psychosocial variables...
August 22, 2018: Journal of Diabetes Science and Technology
Magnus Stueve, Oliver Schnell
BACKGROUND: Various health technology assessment (HTA) agencies review new medical devices worldwide, and their recommendations can be useful in guiding clinical decision making. However, different agencies use different processes and methodologies, resulting in variation in recommendations. OBJECTIVES: The objectives were to review full HTAs for a new technology for diabetes management, flash glucose monitoring (FGM), with the aim of summarizing similarities/differences in processes, methodologies, and recommendations from the perspective of everyday clinical practice...
August 22, 2018: Journal of Diabetes Science and Technology
Goran Petrovski, Marija Zivkovic
AIMS: The aim of the study was to evaluate Facebook group as possible communication tool to improve glucose control in adolescents and young people with type 1 diabetes (T1D). METHODS: This retrospective and cross-sectional study included 728 T1D patients (age 11-25) on continuous subcutaneous insulin infusion (CSII) or multiple daily injections (MDI) treated at the center for insulin pump and glucose sensor in Skopje from January 2012 to December 2017. Data were collected through the electronic medical record system and cross-sectional analysis (telephone, social media (Facebook and Viber) or email)...
August 22, 2018: Journal of Diabetes Science and Technology
Aneesah Khan, Pratik Choudhary
BACKGROUND: Diabetes distress has been linked with suboptimal glycemic control in patients with type 1 diabetes. We evaluated the effect of diabetes distress on self-management behaviors in patients using insulin pumps. METHODS: We analyzed the impact of diabetes distress on self-management behaviors using pump downloads from 129 adults treated with continuous subcutaneous insulin infusion (CSII) at a single hospital clinic. Exclusion criteria were CSII treatment <6 months, pregnancy, hemoglobinopathy, and continuous glucose monitoring/sensor use...
August 12, 2018: Journal of Diabetes Science and Technology
Andjela T Drincic
Self-monitoring of blood glucose is a part of integral care of patients with diabetes mellitus. Understanding and appropriately responding to glucose levels is a fundamental part of self-management. Grady et al's work, published in the current issue of Journal of Diabetes Science and Technology, investigated whether switching people with diabetes from their usual meter to a meter featuring color range indicator (CRI) could improve glycemic control, by facilitating improved understanding of blood glucose targets...
August 10, 2018: Journal of Diabetes Science and Technology
Kirsty Macleod, Laurence B Katz, Hilary Cameron
BACKGROUND: Anecdotal blood glucose assessments conducted by health care professionals (HCPs) in the field have highlighted differences in results when methodology used is not according to best practices for measuring blood glucose. This study assessed the impact on accuracy of blood glucose measurements when methodology deviates from the recommended study design and recommended reference instrument. METHODS: Adults with type 1 or type 2 diabetes provided capillary and venous blood samples for accuracy assessments using OneTouch® Verio® (Verio) and OneTouch® Ultra 2® (Ultra) blood glucose meters (BGM) and two different reference instruments...
August 7, 2018: Journal of Diabetes Science and Technology
Katharine D Barnard, Ralph Ziegler, David C Klonoff, Katarina Braune, Bettina Petersen, Til Rendschmidt, Daniel Finan, Aaron Kowalski, Lutz Heinemann
Biomedical outcomes for people with diabetes remain suboptimal for many. Psychosocial care in diabetes does not fare any better. "Artificial pancreas" (also known as "closed-loop" and "automated insulin delivery") systems present a promising therapeutic option for people with diabetes (PWD)-simultaneously improving glycemic outcomes, reducing the burden of self-management, and improving health-related quality of life. In recent years there has emerged a growing movement of PWD innovators rallying behind the mantra #WeAreNotWaiting, developing "do-it-yourself artificial pancreas systems (DIY APS)...
August 6, 2018: Journal of Diabetes Science and Technology
Ryan Boehm, John Donovan, Disha Sheth, Andrew Durfor, Jason Roberts, Irada Isayeva
BACKGROUND: Electrochemical enzymatic glucose sensors are intended to measure blood or interstitial fluid glucose concentrations. One class of these glucose sensors are continuous glucose monitors (CGMs), indicated for tracking and trending of glucose concentrations in interstitial fluid and as an adjunct to blood glucose testing. Currently approved CGMs employ a glucose oxidase (GOx) electrochemical detection scheme. Potential interfering agents can impact the accuracy of results obtained by glucose sensors, including CGMs...
August 3, 2018: Journal of Diabetes Science and Technology
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