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Journal of Diabetes Science and Technology

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https://www.readbyqxmd.com/read/29332423/first-experiences-with-a-wearable-multisensor-in-an-outpatient-glucose-monitoring-study-part-i-the-users-view
#1
Andreas Caduff, Mattia Zanon, Pavel Zakharov, Martin Mueller, Mark Talary, Achim Krebs, Werner A Stahel, Marc Donath
BACKGROUND: Extensive past work showed that noninvasive continuous glucose monitoring with a wearable Multisensor device worn on the upper arm provides useful information about glucose trends to improve diabetes therapy in controlled and semicontrolled conditions. METHODS: To test previous findings also in uncontrolled in-clinic and outpatient conditions, a long-term study has been conducted to collect Multisensor and reference glucose data in a population of 20 type 1 diabetes subjects...
January 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29332422/unexpected-management-behaviors-in-adolescents-with-type-1-diabetes-using-sensor-augmented-pump-therapy
#2
Mary Binsu Abraham, Kristine Heels, Jennifer A Nicholas, Carol Cole, Rebecca Gebert, Julie Klimek, Tracey Jopling, Geoffrey Ambler, Fergus Cameron, Elizabeth Davis, Timothy W Jones
BACKGROUND: Continuous glucose monitoring can improve glycemic outcomes in individuals with type 1 diabetes. However, the constant exposure to real-time glucose levels can sometimes lead the individual to make some risky choices to address the glycemic excursions. Hence, the purpose of this study was to explore the aberrant management behaviors of youth with type 1 diabetes on sensor-augmented pump therapy (SAPT). METHODS: Participants in a clinical trial using SAPT on Medtronic MiniMed™ 640G pump who experienced deteriorating glycemic control or unexplained hypoglycemia were identified by the health care professional...
January 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29322825/blood-glucose-monitoring-data-should-be-reported-in-detail-when-studies-about-efficacy-of-continuous-glucose-monitoring-systems-are-published
#3
Stefan Pleus, Lutz Heinemann, Guido Freckmann
Recently, two clinical trials about a "sensor-based flash glucose monitoring system" and its efficacy in reducing time in hypoglycemia were published. Interestingly, patients spent more time at low glucose concentrations in these studies than in other studies related to the efficacy of real-time continuous glucose monitoring (rtCGM). Although it is possible that the study populations differed from those in other studies, another potential explanation is that the CGM system used in these two studies had a negative glucose measurement bias...
January 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29320885/a-pilot-study-validating-select-research-grade-and-consumer-based-wearables-throughout-a-range-of-dynamic-exercise-intensities-in-persons-with-and-without-type-1-diabetes-a-novel-approach
#4
Loren Yavelberg, Dessi Zaharieva, Ali Cinar, Michael C Riddell, Veronica Jamnik
BACKGROUND: The increasing popularity of wearable technology necessitates the evaluation of their accuracy to differentiate physical activity (PA) intensities. These devices may play an integral role in customizing PA interventions for primary prevention and secondary management of chronic diseases. For example, in persons with type 1 diabetes (T1D), PA greatly affects glucose concentrations depending on the intensity, mode (ie, aerobic, anaerobic, mixed), and duration. This variability in glucose responses underscores the importance of implementing dependable wearable technology in emerging avenues such as artificial pancreas systems...
January 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29320884/correlation-between-third-trimester-glycemic-variability-in-non-insulin-dependent-gestational-diabetes-mellitus-and-adverse-pregnancy-and-fetal-outcomes
#5
Wanwadee Sapmee Panyakat, Chayawat Phatihattakorn, Apiradee Sriwijitkamol, Prasert Sunsaneevithayakul, Amprapha Phaophan, Aporn Phichitkanka
BACKGROUND: Gestational diabetes mellitus (GDM) is a pregnancy-related metabolic complication. Despite optimal glycemic control from self-monitoring blood glucose (SMBG) in non-insulin-dependent GDM, variations in pregnancy outcomes persist. Glycemic variability is believed to be a factor that causes adverse pregnancy outcomes. Continuous glucose monitoring system (CGMS) detects interstitial glucose values every 5 minutes, and glycemic variability data from CGMS during the third trimester may be a predictor of fetal birth weight and pregnancy outcomes...
January 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29310448/motivations-for-participation-in-an-online-social-media-community-for-diabetes
#6
Katherine White, Achamyeleh Gebremariam, Dana Lewis, Weston Nordgren, James Wedding, Josh Pasek, Ashley Garrity, Emily Hirschfeld, Joyce M Lee
BACKGROUND: Our objectives were to describe individuals' motivations for participation in an online social media community and to assess their level of trust in medical information provided by medical professionals and community members. METHODS: A purposive survey was delivered to participants recruited through posts on the CGM in the Cloud group, Twitter, and blogs. Individuals were asked a series of demographic and social media use questions. RESULTS: A total of 1268 members of the CGM in the Cloud community responded to the survey...
January 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29295634/the-need-to-calculate-target-glucose-levels-when-measuring-changes-in-insulin-sensitivity-during-interventions-for-individuals-with-type-2-diabetes
#7
Nor Azlan Othman, Paul D Docherty, Jeremy D Krebs, Damon A Bell, J Geoffrey Chase
BACKGROUND: Physiological models that are used with dynamic test data to assess insulin sensitivity (SI) assume that the metabolic target glucose concentration ( GTARGET) is equal to fasting glucose concentration ( G0). However, recent research has implied that irregularities in G0 in diabetes may cause erroneous SI values. This study quantifies the magnitude of these errors. METHODS: A clinically validated insulin/glucose model was used to calculate SI with the standard fasting assumption (SFA) G0 = GTARGET...
January 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29291641/use-of-a-smartphone-application-to-reduce-hypoglycemia-in-type-1-diabetes-a-pilot-study
#8
Carly Feuerstein-Simon, Suzan Bzdick, Amitha Padmanabhuni, Puneetpal Bains, Cheryl Roe, Ruth S Weinstock
BACKGROUND: Hypoglycemia and hypoglycemia unawareness are common in long-standing type 1 diabetes (T1D). This pilot study examined the real-world use of a smartphone application (app), which receives meter readings and logs hypoglycemic symptoms, causes, and treatments to reduce hypoglycemia. METHODS: Adults with T1D and recent hypoglycemia synchronized their glucose meter to their smartphone and used the Joslin HypoMap™ app powered by Glooko to track hypoglycemic events...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29291639/the-spanish-availability-and-readability-of-diabetes-apps
#9
Jorge A Rodriguez, Karandeep Singh
BACKGROUND: There is growing evidence supporting the use of mobile health apps for the management of diabetes. Given the disproportionate impact of diabetes on Latinos, especially those with limited English proficiency (LEP) and low literacy, diabetes apps have the potential to address existing health disparities. Our study aimed to understand the current accessibility of diabetes apps for these populations. METHODS: We searched the Android and iOS stores for the term "diabetes" to identify patient-facing diabetes apps...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29291625/system-accuracy-and-user-performance-evaluation-of-an-improved-system-for-self-monitoring-of-blood-glucose
#10
Annette Baumstark, Nina Jendrike, Christina Liebing, Cornelia Haug, Guido Freckmann
An improved test cassette for the integrated Accu-Chek® Mobile system (Roche Diabetes Care GmbH, Mannheim, Germany) has been developed. System accuracy of this improved system was evaluated based on ISO 15197:2013, clause 6.3, for three reagent system lots. According to this standard, at least 95% of the system's measurement results shall be within ±15 mg/dL and ±15% of the results of the comparison method at glucose concentrations <100 mg/dL and ≥100 mg/dL (accuracy criterion A), respectively, and at least 99% of results shall be within consensus error grid zones A and B (accuracy criterion B)...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29284290/occlusion-detection-time-in-insulin-pumps-at-two-different-basal-rates
#11
Guido Freckmann, Ulrike Kamecke, Delia Waldenmaier, Cornelia Haug, Ralph Ziegler
BACKGROUND: The detection of insulin infusion set (IIS) occlusions is an important feature of insulin pumps with regard to patient safety. However, there are no requirements for a time limit until an alarm has to be triggered after an occlusion occurred. The standard IEC 60601-2-24 is applicable for insulin pumps and describes test settings and procedures to determine occlusion detection time (ODT). METHODS: In this study, ODT of six different insulin pump models with different IIS (in total 10 different insulin pump systems) was tested for two basal rates (1...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29281893/adherence-over-time-the-course-of-adherence-to-customized-diabetic-insoles-as-objectively-assessed-by-a-temperature-sensor
#12
Dominic Ehrmann, Monika Spengler, Michael Jahn, Dea Niebuhr, Thomas Haak, Bernhard Kulzer, Norbert Hermanns
BACKGROUND: Temperature sensors are an objective way to assess adherence to diabetic footwear. Good adherence is essential for the prevention of diabetic foot problems. Little is known about the long-term course of adherence in patients at risk for diabetic foot problems. METHOD: A temperature sensor was incorporated into the specialized footwear of patients with type 2 diabetes after their first plantar ulceration. Kaplan-Meier curve was used to analyze when patients started to become nonadherent (not wearing the footwear for two straight weeks)...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29281892/may-the-z-tracking-technique-to-minimize-or-avoid-the-pain-of-insulin-injection-be-an-alternative-to-the-10-second-waiting-technique
#13
İnsaf Altun
No abstract text is available yet for this article.
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29281891/the-current-intermittent-scanning-cgm-device-situation-in-japan-only-adjunctive-use-to-smbg-is-approved-and-the-latest-health-insurance-coverage-details
#14
Takashi Murata, Naoki Sakane, Ken Kato, Atsuhito Tone, Masao Toyoda
No abstract text is available yet for this article.
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29281890/analysis-of-dose-accuracy-injection-force-and-usability-assessment-of-a-new-half-unit-prefilled-insulin-pen
#15
Mallika Bariya, Irina Nayberg
Half-unit insulin pens (HUPs) offer finer gradation of insulin dosing than their integer-unit counterparts, tackling the inaccuracies of dose rounding that make it difficult for insulin-sensitive populations to achieve tight glycemic control. This article analyzes the first prefilled HUP, the Humalog Junior KwikPen, in the context of other, similar devices and the developing landscape of smart insulin pens. The Junior KwikPen's suitability for pediatric patients is assessed in reference to a recent study surveying its accuracy and usability under varying conditions intended to simulate real-world use...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29277104/the-importance-of-the-hawthorne-effect-on-psychological-outcomes-unveiled-in-a-randomized-controlled-trial-of-diabetes-technology
#16
Mary B Abraham, Jennifer A Nicholas, Michael Crone, Trang T Ly, Elizabeth A Davis, Timothy W Jones
No abstract text is available yet for this article.
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29277103/digital-diabetes-management-application-improves-glycemic-outcomes-in-people-with-type-1-and-type-2-diabetes
#17
Reid Offringa, Tong Sheng, Linda Parks, Mark Clements, David Kerr, Michael S Greenfield
BACKGROUND: Diabetes is a chronic condition that requires constant self-management. As a consequence, several software platforms have been developed to facilitate the tracking of diabetes data to improve diabetes management. Our aim was to determine the real-world glycemic benefits of a mobile diabetes management platform used by individuals with type 1 and type 2 diabetes. METHODS: Mobile platform-using (n = 899) and control (n = 900) participants meeting specific minimum data criteria were randomly selected from a database of diabetes users...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29268624/insulin-concentration-in-vials-randomly-purchased-in-pharmacies-in-the-united-states-considerable-loss-in-the-cold-supply-chain
#18
Alan W Carter, Lutz Heinemann
The insulin content in vials/cartridges should be 95 U/ml upon release. No independent confirmation of insulin concentration is available when purchased in the pharmacy (end of the cold supply chain). We quantitatively measured intact insulin in randomly acquired multidose human insulin vials by standard analytical methods. Eighteen 10 ml vials from two manufacturers (M1 and M2) were randomly acquired. The intact insulin concentration ranged from 13.9 to 94.2 U/ml, mean 40.2 U/ml. No vial met the minimum standard of 95 U/ml...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29251064/risk-of-hypoglycemia-during-insulin-infusion-directed-by-paper-protocol-versus-electronic-glycemic-management-system-in-critically-ill-patients-at-a-large-academic-medical-center
#19
Marina Rabinovich, Jessica Grahl, Emily Durr, Rita Gayed, Katleen Chester, Raymie McFarland, Barbara McLean
BACKGROUND: Insulin infusions are commonly utilized to control hyperglycemia in critically ill patients and decrease hyperglycemia associated complications. Safety concerns have been raised in trials evaluating methods of glycemic control regarding the incidence of hypoglycemia and its relationship to increased mortality. Electronic glycemic management systems (eGMS) may result in less variable blood glucose (BG) control and less hypoglycemia. This study aimed to compare BG control, time in target BG range, and the rate of hypoglycemia when critically ill patients were managed with an insulin infusion guided by paper-based protocol (PBP) versus eGMS...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29251063/decreased-rates-of-inpatient-hypoglycemia-following-implementation-of-an-automated-tool-in-the-electronic-medical-record-for-identifying-root-causes
#20
Naina Sinha Gregory, Jane Jeffrie Seley, Jenny Ukena, Sona Shah, Matthew R Fred, Savira Kochhar Dargar, Elizabeth Mauer, Robert J Kim
OBJECTIVE: The objective was to identify root causes of hypoglycemia on medicine inpatient units using an automated tool. Data collected will guide educational interventions aimed at improving patient care and safety by decreasing rates of hypoglycemia. METHODS: A survey was conducted among RNs to identify risk factors for hypoglycemia. Survey data were used to create a hypoglycemia root cause survey tool in the EMR. RNs were prompted to utilize the tool when blood glucose (BG) < 70 mg/dL...
December 1, 2017: Journal of Diabetes Science and Technology
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