journal
https://read.qxmd.com/read/38536628/evaluation-of-the-histologic-and-immunohistochemical-cd34-glutamine-synthetase-findings-in-idiopathic-non-cirrhotic-portal-hypertension-incph
#1
JOURNAL ARTICLE
Melek Büyük, Neslihan Berker, Doğu Vurallı Bakkaloğlu, İbrahim Volkan Şenkal, Zerrin Önal, Mine Güllüoğlu
AIM: Idiopathic non-cirrhotic portal hypertension (INCPH) is a vascular disorder of uncertain origin. Diagnosis can be challenging on liver biopsy. Despite diverse histomorphologic findings documented in literature, studies on the frequency of these findings are lacking. This study aims to assess both the histomorphologic features and the immunoexpression patterns of CD34 and glutamine synthetase (GS) in liver biopsies and searched for their contribution to the pathologic diagnosis of INCPH...
March 27, 2024: Hepatology International
https://read.qxmd.com/read/38528292/global-burden-and-trends-of-acute-viral-hepatitis-among-children-and-adolescents-from-1990-to-2019-a-systematic-analysis-of-the-global-burden-of-disease-study-2019
#2
JOURNAL ARTICLE
Wanglong Xiao, Jingwei Zhao, Yiwen Chen, Xingzhu Liu, Chang Xu, Jiaxu Zhang, Yongbing Qian, Qiang Xia
BACKGROUND: Children and adolescents are at high risk for acute viral hepatitis (AVH), but epidemiological research focusing on them has been overshadowed by adult chronic B and C. We provide global, regional, and national estimates of the AVH burden and their trends on people under 20 years from 1990 to 2019. METHODS: AVH data from Global Burden of Disease Study (GBD) 2019 was used. Incidence and disability-adjusted life years (DALYs) were calculated, analyzing trends with estimated annual percentage change (EAPC) and Joinpoint regression...
March 26, 2024: Hepatology International
https://read.qxmd.com/read/38507160/abstracts
#3
(no author information available yet)
No abstract text is available yet for this article.
March 20, 2024: Hepatology International
https://read.qxmd.com/read/38492132/prophylaxis-of-hepatic-encephalopathy-current-and-future-drug-targets
#4
REVIEW
Sudhir Maharshi, Barjesh Chander Sharma
Hepatic encephalopathy is described by a broad spectrum of neurological and psychiatric aberrations resulting due to advanced liver dysfunction. It is a neurological disorder due to hepatic insufficiency and/or portosystemic shunts. Its clinical presentation includes neuropsychiatric dysfunction ranging from subclinical changes to comatose state. It is a sign of poor prognosis in cirrhotics with a high 1-year mortality. Each episode of hepatic encephalopathy leads to high hospitalization rate, poor prognosis and raised burden of healthcare...
March 16, 2024: Hepatology International
https://read.qxmd.com/read/38485873/safety-of-right-liver-donation-after-improving-steatosis-through-weight-loss-in-living-donors-a-retrospective-study
#5
JOURNAL ARTICLE
Young-In Yoon, Sung-Gyu Lee, Shin Hwang, Ki-Hun Kim, Chul-Soo Ahn, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung, Gil-Chun Park
BACKGROUND: Living donor liver transplantation using hepatic steatosis-improved grafts mitigates donor shortage. Herein, we aimed to evaluate the safety and feasibility of right-lobe adult-to-adult living donor liver transplantation using grafts improved through donor weight loss. METHODS: In this retrospective study conducted in a single institution in the Republic of Korea, we reviewed the medical records of living liver donors who lost ≥ 10% of their body weight to improve steatosis before right lobe donation between January 2015 and December 2020...
March 15, 2024: Hepatology International
https://read.qxmd.com/read/38480604/laparoscopic-liver-resection-is-superior-to-radiofrequency-ablation-for-small-hepatocellular-carcinoma-a-systematic-review-and-meta-analysis-of-propensity-score-matched-studies
#6
JOURNAL ARTICLE
Wen Chen, Xiaodan Lin, Zhenheng Wu, Wei Pan, Qiming Ke, Yanling Chen
BACKGROUND: The approach in small hepatocellular carcinoma (HCC) is controversial, no prospective randomized trials to compare ablative or surgical approaches. We compared the surgical and oncological outcomes after laparoscopic hepatectomy (LH) and radiofrequency ablation (RFA) in small HCC patients based on matched cohort studies that performed propensity score matching (PSM). METHODS: We systemically searched the PubMed, Cochrane Library, Embase, Web of Science, and the Chinese BioMedical Literature (CBM) databases...
March 14, 2024: Hepatology International
https://read.qxmd.com/read/38472608/-dosis-sola-facit-venenum-evidence-for-causality-in-the-association-between-ketamine-and-cholestatic-liver-injury
#7
LETTER
Pedro David Wendel-Garcia, Rea Andermatt, Christian Bode, Sascha David, Klaus Stahl
No abstract text is available yet for this article.
March 13, 2024: Hepatology International
https://read.qxmd.com/read/38472607/surgical-risk-stratification-in-patients-with-cirrhosis
#8
REVIEW
Ana Ostojic, Nadim Mahmud, K Rajender Reddy
Individuals with cirrhosis experience higher morbidity and mortality rates than the general population, irrespective of the type or scope of surgery. This increased risk is attributed to adverse effects of liver disease, encompassing coagulation dysfunction, altered metabolism of anesthesia and sedatives, immunologic dysfunction, hemorrhage related to varices, malnutrition and frailty, impaired wound healing, as well as diminished portal blood flow, overall hepatic circulation, and hepatic oxygen supply during surgical procedures...
March 12, 2024: Hepatology International
https://read.qxmd.com/read/38461186/predictors-of-hbsag-seroclearance-in-patients-with-chronic-hbv-infection-treated-with-pegylated-interferon-%C3%AE-a-systematic-review-and-meta-analysis
#9
REVIEW
Shaowen Jiang, Simin Guo, Yan Huang, Yalin Yin, Jingwen Feng, Huijuan Zhou, Qing Guo, Weijing Wang, Haiguang Xin, Qing Xie
BACKGROUND AND AIMS: The identification of reliable predictors for hepatitis B surface antigen (HBsAg) seroclearance remains controversial. We aimed to summarize potential predictors for HBsAg seroclearance by pegylated interferon-α (PegIFNα) in patients with chronic HBV infection. METHODS: A systematic search of the Cochrane Library, Embase, PubMed, and Web of Science databases was conducted from their inception to 28 September 2022. Meta-analyses were performed following the PRISMA statement...
March 9, 2024: Hepatology International
https://read.qxmd.com/read/38460060/expert-consensus-on-the-diagnosis-and-treatment-of-end-stage-liver-disease-complicated-by-infections
#10
EDITORIAL
Tao Chen, Guang Chen, Guiqiang Wang, Sombat Treeprasertsuk, Cosmas Rinaldi Adithya Lesmana, Han-Chieh Lin, Mamun Al-Mahtab, Yogesh K Chawla, Soek-Siam Tan, Jia-Horng Kao, Man-Fung Yuen, Guan-Huei Lee, Diana Alcantara-Payawal, Nobuaki Nakayama, Zaigham Abbas, Wasim Jafri, Dong-Joon Kim, Ashok Choudhury, Rakhi Mahiwall, Jinlin Hou, Saeed Hamid, Jidong Jia, J S Bajaj, Fusheng Wang, Shiv K Sarin, Qin Ning
End-stage liver disease (ESLD) is a life-threatening clinical syndrome and when complicated with infection the mortality is markedly increased. In patients with ESLD, bacterial or fungal infection can induce or aggravate the occurrence or progression of liver decompensation. Consequently, infections are among the most common complications of disease deterioration. There is an overwhelming need for standardized protocols for early diagnosis and appropriate management for patients with ESLD complicated by infections...
March 9, 2024: Hepatology International
https://read.qxmd.com/read/38451408/correction-to-complementary-role-of-peripheral-and-central-autonomic-nervous-system-on-insulin-like-growth-factor-1-activation-to-prevent-fatty-liver-disease
#11
Itsuo Nagayama, Kenya Kamimura, Takashi Owaki, Masayoshi Ko, Takuro Nagoya, Yuto Tanaka, Marina Ohkoshi, Toru Setsu, Akira Sakamaki, Takeshi Yokoo, Hiroteru Kamimura, Shuji Terai
No abstract text is available yet for this article.
March 7, 2024: Hepatology International
https://read.qxmd.com/read/38451407/are-dairy-products-the-answer-to-metabolic-dysfunction-associated-fatty-liver-disease
#12
EDITORIAL
Kristopher Cho-Hei Lau, Vincent Wai-Sun Wong
No abstract text is available yet for this article.
March 7, 2024: Hepatology International
https://read.qxmd.com/read/38451406/impact-of-chronic-hepatitis-b-and-concurrent-steatosis-on-the-risk-of-hepatocellular-carcinoma
#13
LETTER
Ibrahim Ayada, Jiajing Li, Willem Pieter Brouwer, Robert J de Knegt, Qiuwei Pan
No abstract text is available yet for this article.
March 7, 2024: Hepatology International
https://read.qxmd.com/read/38429497/comments-on-risk-of-dyslipidemia-in-chronic-hepatitis-b-patients-taking-tenofovir-alafenamide-%C3%A2-a-systematic-review-and-meta-analysis
#14
LETTER
Yan Wang, Xiu Sun, Junyan Zhang, Qi Mei
No abstract text is available yet for this article.
March 2, 2024: Hepatology International
https://read.qxmd.com/read/38427145/pre-hepatectomy-dynamic-circulating-tumor-dna-to-predict-pathologic-response-to-preoperative-chemotherapy-and-post-hepatectomy-recurrence-in-patients-with-colorectal-liver-metastases
#15
JOURNAL ARTICLE
Ming Liu, Quan Bao, Tingting Zhao, Longfei Huang, Danhua Zhang, Yanyan Wang, Xiaoluan Yan, Hongwei Wang, Kemin Jin, Wei Liu, Kun Wang, Baocai Xing
OBJECTIVE: To evaluate the predictive value of pre-hepatectomy dynamic circulating tumor DNA (ctDNA) on pathologic response to preoperative chemotherapy and recurrence after liver resection for colorectal liver metastases (CRLM). BACKGROUND: Pathologic response is a predictor of clinical outcomes for patients undergoing hepatectomy for CRLM. Postoperative ctDNA has been proven to be sensitive for recurrence detection. However, few studies investigate the impact of pre-hepatectomy ctDNA on pathologic response and recurrence...
March 1, 2024: Hepatology International
https://read.qxmd.com/read/38424395/nomograms-should-be-noted
#16
EDITORIAL
Shuntaro Obi, Masao Omata
No abstract text is available yet for this article.
March 1, 2024: Hepatology International
https://read.qxmd.com/read/38424394/response-to-letter-to-editor-for-risk-of-dyslipidemia-in-chronic-hepatitis-b-patients-taking-tenofovir-alafenamide-a-systematic-review-and-meta-analysis
#17
LETTER
Jin Wook Park, Jeong-Ju Yoo, Sang Gyune Kim, Young Seok Kim
No abstract text is available yet for this article.
February 29, 2024: Hepatology International
https://read.qxmd.com/read/38416312/asian-pacific-association-for-the-study-of-the-liver-clinical-practice-guidelines-on-liver-transplantation
#18
EDITORIAL
Dong-Sik Kim, Young-In Yoon, Beom Kyung Kim, Ashok Choudhury, Anand Kulkarni, Jun Yong Park, Jongman Kim, Dong Hyun Sinn, Dong Jin Joo, YoungRok Choi, Jeong-Hoon Lee, Ho Joong Choi, Ki Tae Yoon, Sun Young Yim, Cheon-Soo Park, Deok-Gie Kim, Hae Won Lee, Won-Mook Choi, Young Eun Chon, Woo-Hyoung Kang, Jinsoo Rhu, Jae Geun Lee, Yuri Cho, Pil Soo Sung, Han Ah Lee, Ji Hoon Kim, Si Hyun Bae, Jin Mo Yang, Kyung-Suk Suh, Mamun Al Mahtab, Soek Siam Tan, Zaigham Abbas, Ananta Shresta, Shahinul Alam, Anil Arora, Ashish Kumar, Pravin Rathi, Ruveena Bhavani, Charles Panackel, Kuei Chuan Lee, Jun Li, Ming-Lung Yu, Jacob George, Tawesak Tanwandee, Sen-Yung Hsieh, Chee Chien Yong, Mohamed Rela, H C Lin, Masao Omata, Shiv Kumar Sarin
Liver transplantation is a highly complex and challenging field of clinical practice. Although it was originally developed in western countries, it has been further advanced in Asian countries through the use of living donor liver transplantation. This method of transplantation is the only available option in many countries in the Asia-Pacific region due to the lack of deceased organ donation. As a result of this clinical situation, there is a growing need for guidelines that are specific to the Asia-Pacific region...
February 28, 2024: Hepatology International
https://read.qxmd.com/read/38409495/dairy-products-intake-and-prevalence-incidence-and-recovery-of-non-alcoholic-fatty-liver-disease-in-chinese-population
#19
JOURNAL ARTICLE
Yurou Xu, Youyi Wang, Qi Zhao, Bo Chen, Na Wang, Tiejun Zhang, Yonggen Jiang, Yiling Wu, Na He, Genming Zhao, Xing Liu
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a growing public health concern. Modifiable factors such as diet and lifestyle are of research interest in preventing or reversing the disease. The relationship between dairy products and NAFLD remains unclear. METHODS: In this cohort study, 36,122 participants aged 20-74 were enrolled by multi-stage, stratified, randomized cluster sampling from 2016 to 2017. A total of 25,085 participants finished at least one follow-up visit from 2019 to 2023...
February 26, 2024: Hepatology International
https://read.qxmd.com/read/38402364/chinese-guideline-for-the-diagnosis-and-treatment-of-drug-induced-liver-injury-an-update
#20
EDITORIAL
Yimin Mao, Shiwu Ma, Chenghai Liu, Xiaoyan Liu, Minghua Su, Dongliang Li, Yiling Li, Gongying Chen, Jun Chen, Jinjun Chen, Jingmin Zhao, Xiaoyan Guo, Jieting Tang, Yuzheng Zhuge, Qing Xie, Wen Xie, Rongtao Lai, Dachuan Cai, Qingxian Cai, Yang Zhi, Xiaoyun Li
Drug-induced liver injury (DILI) is an important adverse drug reaction that can lead to acute liver failure or even death in severe cases. Currently, the diagnosis of DILI still follows the strategy of exclusion. Therefore, a detailed history taking and a thorough and careful exclusion of other potential causes of liver injury is the key to correct diagnosis. This guideline was developed based on evidence-based medicine provided by the latest research advances and aims to provide professional guidance to clinicians on how to identify suspected DILI timely and standardize the diagnosis and management in clinical practice...
February 24, 2024: Hepatology International
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