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Obesity Research & Clinical Practice

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https://www.readbyqxmd.com/read/28228348/carbon-dioxide-in-carbonated-beverages-induces-ghrelin-release-and-increased-food-consumption-in-male-rats-implications-on-the-onset-of-obesity
#1
Dureen Samandar Eweis, Fida Abed, Johnny Stiban
BACKGROUND: The dangerous health risks associated with obesity makes it a very serious public health issue. Numerous studies verified a correlation between the increase in obesity and the parallel increase in soft drink consumption among world populations. The effects of one main component in soft drinks namely the carbon dioxide gas has not been studied thoroughly in any previous research. METHODS: Male rats were subjected to different categories of drinks and evaluated for over a year...
February 19, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28215850/predictors-of-adolescents-weight-misclassification-a-longitudinal-study
#2
Abdulaziz D Aloufi, Jake M Najman, Abdullah A Mamun
OBJECTIVE: To examine adolescents' and mothers' misclassification of the adolescents' body weight and associated early life predictors. METHODS: Data are from a sample of women and their children who were part of a longitudinal Australian birth cohort study. We analysed data of 3925 adolescents, 3721 mothers, and 2593 mother-offspring pairs. At the 14-year follow up, we derived adolescents' body weight category (underweight, normal or overweight) based on their measured height and weight and adolescents reported their similar subjective weight categories...
February 16, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28163011/aerobic-endurance-training-improves-nonalcoholic-fatty-liver-disease-nafld-features-via-mir-33-dependent-autophagy-induction-in-high-fat-diet-fed-mice
#3
Parvin Ghareghani, Mehrnoosh Shanaki, Saeideh Ahmadi, Ali Reza Khoshdel, Neda Rezvan, Reza Meshkani, Maryam Delfan, Sattar Gorgani-Firuzjaee
Due to changes in life style, obesity and obesity related complication such as insulin resistance, type 2 diabetes and non-alcoholic fatty liver disease caused worldwide health problems. Regular exercise has been frequently prescribed to combat metabolic complication of obesity but its molecular mechanism has not been fully illustrated. We investigated molecular mechanism of lipid lowering effect of exercise training in high fat diet fed mice by focusing on miR-33 expression and autophagy pathway. 24 mice were assigned to normal chow (NC) (n=8), high-fat diet (HFD) (n=16) group and subjected to NC and HFD for 13-weeks...
February 2, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28161303/comparison-of-exenatide-and-acarbose-on-intra-abdominal-fat-content-in-patients-with-obesity-and-type-2-diabetes-a-randomized-controlled-trial
#4
Li Shi, Jing Zhu, Ping Yang, Xiaoqiang Tang, Wenlong Yu, Changjie Pan, Moyu Shen, Dalong Zhu, Jinluo Cheng, Xinhua Ye
OBJECTIVE: To investigate exenatide, a GLP-1 analogue, compared with acarbose, for intra-abdominal fat reduction in patients with obesity and type-2 diabetes. METHODS: This randomized controlled trial included 36 patients with obesity and type-2 diabetes, who were metformin-unresponsive, receiving metformin/exenatide (GLP-1 group) or metformin/acarbose (control group) for 3 months. Primary end-point: intra-abdominal fat content from baseline to 3 months; Secondary end-points: changes in fasting blood glucose, glycated haemoglobin (HbAlc), fasting insulin, blood lipids, weight, body mass index, and inflammatory cytokines from baseline to 3 months...
February 1, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28111084/prepregnancy-maternal-diabetes-combined-with-obesity-impairs-placental-mitochondrial-function-involving-nrf2-are-pathway-and-detrimentally-alters-metabolism-of-offspring
#5
Yang Duan, Fuqiang Sun, Shengshun Que, Yueqin Li, Suyan Yang, Geli Liu
Metabolic disorders usually increase the level of reactive oxygen species (ROS) and damage mitochondrial function. The placenta supplies nutrients and hormonal signals to the fetus for regulating fetal metabolism, and is also prone to injury by oxidants. The aim of this study was to determine the effect of pre-existing maternal type 2 diabetes mellitus (DM) combined with obesity on placental mitochondrial function and metabolism disorders of offspring. The study included 96 pregnant women. The women were put into the following groups: healthy women (control, n=24), women with DM (DM, n=24), women with obesity (OB, n=24) and women with both DM and obesity (DM+OB, n=24)...
January 19, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28094226/relationship-between-age-and-cardiometabolic-index-in-japanese-men-and-women
#6
Ichiro Wakabayashi
BACKGROUND: Cardiometabolic index (CMI) is a new discriminator of the risk of diabetes and has been reported to be associated with the degree of atherosclerosis. However, it is unknown whether and how age influences CMI. METHODS: The subjects were Japanese men (n=35684) and women (n=18793) aged ≥35 and ≤70 years who had received periodic health examinations at workplaces. CMI and its association with diabetes were compared among different age groups in men and women...
January 13, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28089658/utility-of-body-mass-index-waist-to-height-ratio-and-cardiorespiratory-fitness-thresholds-for-identifying-cardiometabolic-risk-in-10-4-17-6-year-old-children
#7
Duncan S Buchan, Julien S Baker
OBJECTIVE: To examine the utility of Body Mass Index (BMI), Waist-to-Height-Ratio (WHtR) and cardiorespiratory fitness thresholds to identify cardiometabolic risk in youth. METHODS: Cross-sectional cardiometabolic risk factor variables on 534 children aged 10.4-17.6 years of age (52% boys) from the United Kingdom were used. Binary logistic regression and receiver operating characteristic curves were used to examine the utility of established age and gender specific thresholds for BMI, WHtR and cardiorespiratory fitness to identify individuals with increased cardiometabolic risk (increased clustered triglycerides, HDL-cholesterol, systolic blood pressure and glucose)...
January 12, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28089396/comparison-between-measured-and-perceived-weight-status-in-a-nationally-representative-sample-of-australian-adults
#8
Jessica Herbert, Karen Louise Peterson, Laura Alston, Steven Allender, Melanie Nichols
BACKGROUND: Many individuals may not accurately perceive whether their weight status poses a health risk. This paper aimed to determine how accurately Australians perceived their weight status compared to objective measurements, and to determine what factors were associated with underestimating weight status. METHODS: Participants were 7947 non-pregnant adults from the 2011 to 2012 Australian National Nutrition and Physical Activity Survey, with complete data for self-reported and measured weight status...
January 11, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28089395/royal-jelly-ameliorates-diet-induced-obesity-and-glucose-intolerance-by-promoting-brown-adipose-tissue-thermogenesis-in-mice
#9
Takeshi Yoneshiro, Ryuji Kaede, Kazuki Nagaya, Julia Aoyama, Mana Saito, Yuko Okamatsu-Ogura, Kazuhiro Kimura, Akira Terao
INTRODUCTION: Identification of thermogenic food ingredients is potentially a useful strategy for the prevention of obesity and related metabolic disorders. It has been reported that royal jelly (RJ) supplementation improves insulin sensitivity; however, its impacts on energy expenditure and adiposity remain elusive. We investigated anti-obesity effects of RJ supplementation and their relation to physical activity levels and thermogenic capacities of brown (BAT) and white adipose tissue (WAT)...
January 11, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28073639/association-between-volume-and-glucose-metabolism-of-abdominal-adipose-tissue-in-healthy-population
#10
Hyun Woo Kwon, Sang Mi Lee, Jeong Won Lee, Jung-Eun Oh, Se-Whan Lee, Shin Young Kim
OBJECTIVE: We investigated the association of adipose tissue volume and metabolic activity with cardiometabolic risk factors. METHODS: 232 healthy subjects (43.23±4.09y) having (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) results were included. Clinical information, anthropometry and laboratory results were obtained. Volume and metabolic activity of subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) was obtained from FDG PET/CT...
January 7, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28065384/the-effects-of-fat-induced-obesity-on-bone-metabolism-in-rats
#11
Wei Li, Peng Xu, Cuizhe Wang, Xiaodan Ha, Yajuan Gu, Yan Wang, Jun Zhang, Jianxin Xie
OBJECTIVE: The aim of the current study was to investigate the effects of obesity, induced via a high-fat diet, on bone metabolism in rats. METHODS: Two hundred healthy Wistar male rats aged 4 weeks were fed a standard diet and a high-fat diet. At specific time points (week 0, 4, 6, 8, and 10), plasma was collected to determine the levels of glucose and lipid metabolism. Additionally, enzyme-linked immunoassays were performed to determine the plasma levels of adipocyte and bone metabolism factors...
January 3, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28057417/long-term-effects-of-bariatric-surgery-on-peripheral-endothelial-function-and-coronary-microvascular-function
#12
LETTER
Pierpaolo Tarzia, Gaetano A Lanza, Alfonso Sestito, Angelo Villano, Giulio Russo, Stefano Figliozzi, Priscilla Lamendola, Antonio De Vita, Filippo Crea
BACKGROUND: We previously demonstrated that bariatric surgery (BS) leads to a short-term significant improvement of endothelial function and coronary microvascular function. In this study we assessed whether BS maintains its beneficial effect at long-term follow up. DESIGN: We studied 19 morbidly obese patients (age 43±9years, 12 women) without any evidence of cardiovascular disease who underwent BS. Patients were studied before BS, at 3 months and at 4.0±1.5years follow up...
January 2, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28057416/laparoscopic-sleeve-gastrectomy-modifies-cholesterol-synthesis-but-not-cholesterol-absorption
#13
LETTER
S De Vuono, M A Ricci, D Siepi, M Boni, A Gentili, M Scavizzi, G Daviddi, P Labate, A R Roscini, G Lupattelli
BACKGROUND AND AIMS: Each bariatric surgery procedure impacts differently on cholesterol synthesis and absorption. Although a restrictive procedure, sleeve gastrectomy resolves diabetes mellitus and, like mixed-type procedures, induces early changes in gastrointestinal hormones. To our knowledge the present study is the first to assess the effects of sleeve gastrectomy on cholesterol synthesis and absorption. METHODS AND RESULTS: 42 consecutive subjects with obesity and sleeve gastrectomy candidates were included in the study together with a control group of 20 subjects without obesity...
January 2, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28034698/laparoscopic-sleeve-gastrectomy-on-a-morbidly-obese-patient-with-situs-inversus-totalis-a-case-study-and-systematic-review-of-the-literature
#14
Mehmet Aziret, Kerem Karaman, Metin Ercan, Erdal Birol Bostancı, Musa Akoğlu
INTRODUCTION: Situs inversus totalis (SIT) is a condition where the internal organs or organ systems are located contra-laterally to the norm, forming a mirror image. Laparoscopic sleeve gastrectomy (LSG) is an effective bariatric procedure that has become more common over the last two decades. We report on a morbidly obese patient with SIT who underwent a successful LSG. CASE REPORT: A 54-year-old female morbidly obese patient (136k; 167cm; body mass index (BMI): 48kg/m(2)) was admitted for bariatric surgery...
December 26, 2016: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28007535/association-between-weight-status-and-men-s-positive-mental-health-the-influence-of-marital-status
#15
Francine de Montigny, Lyne Cloutier, Sophie Meunier, Caroline Cyr, Simon Coulombe, Gilles Tremblay, Nathalie Auger, Bernard Roy, Isabelle Gaboury, Brigitte Lavoie, Harold Dion, Janie Houle
The purpose of this study was to (1) examine the association between weight status and men's positive mental health, defined as the presence of symptoms of emotional, psychological, and social well-being, and (2) evaluate the moderating effect of marital status. A total of 645 men aged between 19 and 71 years self-reported their height and weight and answered a questionnaire measuring their emotional, psychological, and social well-being. Analysis of variance revealed that mean levels of emotional, psychological, and social well-being did not significantly differ according to men's weight status...
December 19, 2016: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28007534/fkbp5-polymorphism-is-associated-with-insulin-resistance-in-children-and-adolescents-with-obesity
#16
Marta Fichna, Izabela Krzyśko-Pieczka, Magdalena Żurawek, Bogda Skowrońska, Danuta Januszkiewicz-Lewandowska, Piotr Fichna
OBJECTIVE: Since metabolic syndrome shares several clinical features with hypercortisolism, it was hypothesised that genes altering individual glucocorticoid (GC) sensitivity might be implicated in pathogenesis of obesity and its adverse outcomes. FKBP5 gene encodes a chaperon protein in the GC receptor (GR) complex, which modulates steroid action upon target genes. Its functional variant, rs1360780, may enhance FKBP5 gene transcription, affect GR signalling and thereby influence the hypothalamo-pituitary-adrenal axis...
December 19, 2016: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/27956218/an-intensive-lifestyle-intervention-reduces-circulating-oxidised-low-density-lipoprotein-and-increases-human-paraoxonase-activity-in-obese-subjects
#17
Angelo Russo, Irene Pirisinu, Carmine Vacca, Elisa Reginato, Emilia Sbroma Tomaro, Roberto Pippi, Cristina Aiello, Vincenzo Nicola Talesa, Pierpaolo De Feo, Rita Romani
OBJECTIVE: Obesity has a great impact on cardiovascular morbidity and mortality, the treatment of this pathological state is important given the significant health consequences. Lifestyle and behaviour changes play a significant role in weight management. The purpose of this study was to investigate the impact of an intensive multidisciplinary lifestyle intervention on well-known atherogenic factors in a group of overweight and obese subjects. METHODS: A total of 44 people with overweight/obesity underwent a lifestyle intervention based on nutritional education, psychological support and a 3-month exercise training program with a frequency of twice a week...
December 9, 2016: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/27939216/the-value-of-health-and-weight-loss-among-primary-care-patients-with-moderate-to-severe-obesity-do-quality-of-life-factors-have-a-larger-influence-than-comorbidities
#18
LETTER
Christina C Wee, Mary B Hamel, Karen W Huskey, Roger B Davis
No abstract text is available yet for this article.
December 6, 2016: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/27931766/a-comparison-of-move-versus-telemove-programs-for-weight-loss-in-veterans-with-obesity
#19
Thomas Rutledge, Jane A Skoyen, Julie A Wiese, Kathleen M Ober, Gina N Woods
BACKGROUND: Obesity is a leading contributor to disability. Treatment approaches incorporating telehealth technologies are becoming increasingly popular in treating obesity, but their benefits relative to established behavioural weight loss therapies are poorly understood. The objective of this study was to compare a new telehealth treatment (TeleMOVE) to an established behavioural treatment (MOVE!) among Veterans with obesity. METHODS: This was an observational study of Veterans in the TeleMOVE or MOVE! programs between October, 2011 and March, 2013...
December 5, 2016: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/27889358/the-hypertriglyceridemic-waist-and-waist-to-height-ratio-phenotypes-and-chronic-kidney-disease-cross-sectional-and-prospective-investigations
#20
Azra Ramezankhani, Fereidoun Azizi, Arash Ghanbarian, Donna Parizadeh, Farzad Hadaegh
AIMS: We investigated the association between two hypertriglyceridemic waist (HW) and waist-to height ratio (HWHtR) phenotypes and chronic kidney disease (CKD) using cross sectional and prospective analysis. METHODS: Data of 12,012 individuals (44% men) of the Tehran Lipid and Glucose Study (TLGS) at two phases [(1999-2001) and (2002-2005)], were used for cross-sectional analysis. This population was followed until 2014 with median follow-up 12.4 years (95% confidence interval (CI): 11...
November 23, 2016: Obesity Research & Clinical Practice
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