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Obesity Research & Clinical Practice

Fariza Fadzil, Khadijah Shamsuddin, Sharifa Ezat Wan Puteh, Azmi Mohd Tamil, Shuhaila Ahmad, Noor Shaheeran Abdul Hayi, Azah Abdul Samad, Ruhaini Ismail, Nor Izzah Ahmad Shauki
BACKGROUND: Women of childbearing age are predisposed to becoming overweight or obese. This study determines the mean, prevalence and factors associated with 6 months postpartum weight retention among urban Malaysian mothers. METHODS: A prospective cohort study was conducted at baseline (after delivery), 2, 4 and 6 months postpartum. From 638 eligible mothers initially recruited, 420 completed until 6 months. Dependent variable was weight retention, defined as difference between weight at 6 months postpartum and pre-pregnancy weight, and weight retention ≥5kg was considered excessive...
June 27, 2018: Obesity Research & Clinical Practice
Chien-Hung Liao, Chao-Yung Wang, Keng-Hau Liu, Yu-Yin Liu, Ming-Shien Wen, Ta-Sen Yeh
The physiological roles and clinical impacts of the differences between visceral fat (VF) and subcutaneous fat (SF) are unclear. The present study aimed to compare the miRNA signatures between visceral fat (VF) and subcutaneous fat (SF) and study their influences on outcomes of bariatric surgery. To study the microRNA signatures of the VF and SF in obesity, we performed paired microRNA arrays of the adipose tissues from 20 bariatric surgery patients. The microRNA analysis identified miR-122 as the most significant signature between VF and SF...
June 27, 2018: Obesity Research & Clinical Practice
Misuzu Fujita, Yasunori Sato, Kengo Nagashima, Sho Takahashi, Akira Hata
OBJECTIVE: We aimed to reveal the association between body mass index (BMI) and medical costs in the current Japanese population, and to estimate the population attributable fraction (PAF) of medical costs due to overweight and obesity. METHODS: A generalized linear mixed model with log link function and gamma distribution was used to evaluate the association between BMI and medical costs in 34,537 beneficiaries of the National Health Insurance aged 40-69 years in Chiba City...
June 21, 2018: Obesity Research & Clinical Practice
Yu-Tsung Chou, Hsiang-Ju Cheng, Jin-Shang Wu, Yi-Ching Yang, Chieh-Ying Chou, Chih-Jen Chang, Feng-Hwa Lu
OBJECTIVE: The association of sleep duration/quality with nonalcoholic fatty liver disease (NAFLD) is inconclusive. Several important covariates were not adjusted concomitantly in some studies, and the severity of NAFLD was not considered. Furthermore, the gender impact of sleep duration or sleep quality on NAFLD remains unclear. We thus aimed to examine the association of sleep duration and quality with NAFLD by gender in a Taiwanese population. METHODS: A total of 6663 subjects aged 18 years or more were enrolled...
June 18, 2018: Obesity Research & Clinical Practice
Andy Sharma
INTRODUCTION: While the Body Mass Index (BMI) did not change significantly for men from 2005 to 2014 in the United States, women exhibited an upward linear trend. Hispanic and Black women, in particular, showed a dramatic increase. Therefore, the objective of this study was to examine the association between BMI and mobility limitations for non-institutionalised middle-aged and older Black, Hispanic, and White women. METHODS: The International Classification of Functioning, Disability, and Health model was applied to a sample of 2865 Black, 1846 Hispanic, and 9721 White women categorised as middle-aged and older (i...
June 16, 2018: Obesity Research & Clinical Practice
R B Perez, S Dixon, S Culver, C D Sletten
Chronic pain and obesity are topics of increasing concern. When both diagnoses are present in the same patient, treatment can be complicated. This is a retrospective case-study looking at outcomes across the continuum of care for a patient with Grade III Obesity and chronic widespread pain. The patient completed a Pain Rehabilitation Center program. Progression was realised by following a deliberate, daily regimen, allowing for consistent activity despite the presence of significant physical symptoms and emotional distress...
May 31, 2018: Obesity Research & Clinical Practice
J S Wheat, S Clarkson, S W Flint, C Simpson, D R Broom
OBJECTIVE: Three dimensional (3D) surface imaging is a viable alternative to traditional body morphology measures, but the feasibility of using this technique with people with obesity has not been fully established. Therefore, the aim of this study was to investigate the validity, repeatability and acceptability of a consumer depth camera 3D surface imaging system in imaging people with obesity. METHODS: The concurrent validity of the depth camera based system was investigated by comparing measures of mid-trunk volume to a gold-standard...
May 21, 2018: Obesity Research & Clinical Practice
Stephen Fitter, Andrew C W Zannettino
No abstract text is available yet for this article.
May 2018: Obesity Research & Clinical Practice
Yvonne C Anderson, William Leung, Cameron C Grant, Tami L Cave, José G B Derraik, Wayne S Cutfield, Nicola M Pereira, Paul L Hofman, Trudy A Sullivan
OBJECTIVE: To determine whether Whānau Pakari, a home-based, 12-month multi-disciplinary child obesity intervention programme was cost-effective when compared with the prior conventional hospital-based model of care. METHODS: Whānau Pakari trial participants were recruited January 2012-August 2014, and randomised to either a high-intensity intervention (weekly sessions for 12 months with home-based assessments and advice, n=100) or low-intensity control (home-based assessments and advice only, n=99)...
May 2018: Obesity Research & Clinical Practice
Cécile Bétry, Stéphane Thobois, Martine Laville, Emmanuel Disse
Despite a better understanding of obesity pathophysiology, treating this disease remains a challenge. New therapeutic options are needed. Targeting the brain is a promising way, considering both the brain abnormalities in obesity and the effects of bariatric surgery on the gut-brain axis. Deep brain stimulation could be an alternative treatment for obesity since this safe and reversible neurosurgical procedure modulates neural circuits for therapeutic purposes. We aimed to provide a critical review of published clinical and preclinical studies in this field...
May 2018: Obesity Research & Clinical Practice
Mirjam C M Wever, Alexandra E Dingemans, Tiny Geerets, Unna N Danner
The Risk factors for Binge Eating Disorder in Overweight (REO) questionnaire is a screening tool for nutritionists to discriminate between individuals with obesity with and without Binge Eating Disorder (BED). The first study tested the discriminative ability of the REO and identified an optimal cut-off value. In the second study this cut-off value was used to identify individuals with and without BED from a sample of individuals with obesity visiting a nutritionist and compared clinical and personality characteristics with a group of individuals officially diagnosed with BED...
March 9, 2018: Obesity Research & Clinical Practice
Kevin M Fitzpatrick, Xuan Shi, Don Willis, Jill Niemeier
OBJECTIVES: Extant research clearly points to a correlation between place and health, specifically as it pertains to chronic diseases like obesity. The present study examines this relationship among a diverse set of compositional place indicators and obesity rates across census tracts in the 500 largest cities in the United States. METHODS: Using data compiled from the Robert Wood Johnson Foundation 500 Cities project and the Census' American Community Survey, the analyses examined aggregate relationships between sociodemographic, socioeconomic, and housing characteristics of census tracts and crude prevalence obesity rates in over 27,000 census tracts located in the 500 largest cities in the United States...
March 8, 2018: Obesity Research & Clinical Practice
Veronica Moreno-Viedma, Matteo Tardelli, Maximilian Zeyda, Maria Sibilia, J Deborah Burks, Thomas M Stulnig
OBJECTIVE: Osteopontin (OPN, Spp1) is a protein upregulated in white adipose tissue (WAT) of obese subjects. Deletion of OPN protects mice from high-fat diet-induced WAT inflammation and insulin resistance. However, the alterations mediated by loss of OPN in WAT before the obesogenic challenge have not yet been investigated. Therefore, we hypothesised that the lack of OPN might enhance the pro-adipogenic micro environment before obesity driven inflammation. METHODS: OPN deficiency was tested in visceral (V) and subcutaneous (SC) WAT from WT and Spp1-/- female mice...
March 6, 2018: Obesity Research & Clinical Practice
Shwetha Iyer, Melanie Jay, William Southern, Sheira Schlair
OBJECTIVE: To evaluate obesity counseling competence among residents in a primary care training program METHODS: We delivered a 3h obesity curriculum to 28 Primary Care residents and administered a pre-curriculum and post curriculum survey looking specifically at self-assessed obesity counseling competence. RESULTS: Nineteen residents completed both the pre curriculum survey and the post curriculum survey. The curriculum had a positive impact on residents' ability to ascertain patient's stage of change, use different methods to obtain diet history (including 24h recall, food record or food frequency questionnaire), respond to patient's questions regarding treatment options, assist patients in setting realistic goals for weight loss based on making permanent lifestyle changes, and use of motivational interviewing to change behavior...
March 2018: Obesity Research & Clinical Practice
James D Nobles, Arnaldo Perez, Joseph A Skelton, Nicholas D Spence, Geoff D Ball
Engagement denotes the extent to which, and how, individuals participate in weight management (WM) services. Effective WM services should generate meaningful outcomes and promote high participant engagement; however, research is predominantly focused on the former. Given that engagement is a poorly understood phenomenon, and that engagement-related concepts are often used synonymously (e.g., dropout and attrition), the engagement pathway is hereby introduced. This pathway defines key concepts (e.g., recruitment, adherence, attrition) and their relationships in the enrolment, intervention, and maintenance stages of treatment...
March 2018: Obesity Research & Clinical Practice
Seon-Joo Park, Hae-Jeung Lee
OBJECTIVE: Breastfeeding is generally known to reduce the risk of childhood overweight and obesity. However, the results are controversial between countries, and nationwide data are rare. This study assessed the relationship between breastfeeding types and overweight incidence using nationwide longitudinal data in Korea. METHODS: We analysed 774,764 infants who participated in the longitudinal nationwide data from the Korea National Children's Health Examination 2007-2013...
March 2018: Obesity Research & Clinical Practice
Maryam Kebbe, Arnaldo Perez, Geoff D C Ball
Shared decision-making (SDM) is central to personalising health and medical decisions. This decisional model encourages patients to act as managers of their own care while maintaining a partnership with health professionals. Although applied to some conditions, SDM has been used infrequently in pediatric weight management (PWM). Herein, we highlight the applicability and usefulness of SDM in making several important decisions related to PWM, including referral-making to different levels of care and treatment initiation and implementation...
March 2018: Obesity Research & Clinical Practice
Tzu-I Tsai, Shoou-Yih D Lee
OBJECTIVE: Develop/validate a weight-specific health literacy instrument. METHODS: The development of weight-specific health literacy measurement consisted of seven phases: (a) a literature review; (b) consultation with weight management experts; (c) generation of an item pool; (d) selection of items via the Delphi method; (e) pilot testing; (f) a national survey; and (g) examination of the psychometric properties of the results. RESULTS: A random sample of 362 Taiwanese adults completed the face-toface survey...
March 2018: Obesity Research & Clinical Practice
Priya Sumithran, Christine Houlihan, Alexis Shub, Leonid Churilov, Natasha Pritchard, Sarah Price, Elif Ekinci, Joseph Proietto, Michael Permezel
BACKGROUND: Although population-based studies indicate that on average, women gain 1-2kg between pregnancies, women with obesity often attribute its development to childbearing. There is little contemporary data available regarding how commonly this occurs, particularly in women of different body mass index (BMI) categories. The aim of this study was to examine inter-pregnancy weight changes among women at a tertiary obstetric hospital in Melbourne, Australia. METHODS: This was a retrospective review of data from the Birthing Outcomes System electronic record of 19,617 women aged 20 years or older, who delivered at least two consecutive singleton infants at ≥37 weeks' gestation at Mercy Hospital for Women between December 1994 and December 2015...
March 2018: Obesity Research & Clinical Practice
Zahra Arab Sadeghabadi, Mitra Nourbakhsh, Parvin Pasalar, Solaleh Emamgholipour, Abolfazl Golestani, Bagher Larijani, Maryam Razzaghy-Azar
BACKGROUND: Sirtuins, including SIRT1 and SIRT2, are longevity-associated deacetylase enzymes that modulate metabolic homeostasis in response to the cellular energy state. Adenosine monophosphate activated protein kinase (AMPK) and SIRT1 are interrelated and share several common target pathways. This study aimed to evaluate the SIRT1 and SIRT2 gene expression in peripheral blood mononuclear cells (PBMCs) as well as plasma levels of AMPK, in obese children and adolescents. MATERIALS AND METHODS: Participants included 60 children and adolescents (30 obese and 30 age- and gender-matched control subjects)...
March 2018: Obesity Research & Clinical Practice
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