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Obesity Research & Clinical Practice

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https://www.readbyqxmd.com/read/28528799/a-multifactorial-obesity-model-developed-from-nationwide-public-health-exposome-data-and-modern-computational-analyses
#1
LisaAnn S Gittner, Barbara J Kilbourne, Ravi Vadapalli, Hafiz M K Khan, Michael A Langston
STATEMENT OF THE PROBLEM: Obesity is both multifactorial and multimodal, making it difficult to identify, unravel and distinguish causative and contributing factors. The lack of a clear model of aetiology hampers the design and evaluation of interventions to prevent and reduce obesity. METHODS: Using modern graph-theoretical algorithms, we are able to coalesce and analyse thousands of inter-dependent variables and interpret their putative relationships to obesity...
May 18, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28522388/trends-in-socioeconomic-costs-of-morbid-obesity-among-korean-adults-2009-2013-data-from-national-health-insurance-service
#2
Jae-Woo Lee, Young-Eun Choi, Dong-Wook Kim, Sunmi Lee, Kyung-Hee Cho
As the prevalence of morbid obesity increased in Korea, the estimation of the accurate socioeconomic costs by morbid obesity was required; we analysed national medical costs through the big data. From 2009 year to 2013 year, Direct Costs (DC) for medical costs, transit costs and nursing costs and Indirect Costs (IC) for Future Income Loss (FIL) and Productivity Loss (PL) of morbid obesity (BMI≥30) were calculated, and socioeconomic costs were estimated by applying Population Attributable Risk (PAR) proportion according to obesity related diseases...
May 15, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28506856/bariatric-surgery-revisions-and-private-health-insurance
#3
Samantha B Meyer, Campbell Thompson, Paul Hakendorf, Chris Horwood, Darlene McNaughton, John Gray, Paul R Ward, Lillian Mwanri, Sue Booth, Lilian Kow, Jacob Chisholm
OBJECTIVE: To identify: 1. The percentage of bariatric procedures that are revisions; 2. What proportion of bariatric revision procedures in public hospitals are for patients whose primary weight loss procedure occurred in a private hospital; 3. The age, sex and level of socioeconomic disadvantage of patients needing revisions. METHODS: An analysis of patient level admission data from the Integrated South Australian Activity Collection (ISAAC) was performed. Data were collected on all revisions for weight loss related procedures at all South Australian public and private hospitals, between 2000-2015 using the ISAAC codes for revision procedures...
May 12, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28499848/understanding-obesity-in-the-context-of-an-indigenous-population-a-qualitative-study
#4
Ricky Bell, Catherine Smith, Leigh Hale, Geoffrey Kira, Steve Tumilty
BACKGROUND: Obesity is a progressive global phenomenon that is disparately prevalent amongst Indigenous populations. While there is a growing body of literature investigating the extrinsic contributors to obesity, there is a lack of evidence to elucidate intrinsic drivers in the context of an Indigenous population. METHODS: Qualitative research theory, inclusive of Indigenous knowledge systems, was applied to the narratives of 15 Indigenous (Māori) people aged between 18 and 65 to contextualise their understandings of obesity...
May 9, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28483477/trends-in-the-prevalence-of-underweight-obesity-abdominal-obesity-and-their-related-lifestyle-factors-in-korean-young-adults-1998-2012
#5
Jisun Lim, Hye Soon Park
BACKGROUND: This study aimed to assess trends of underweight, obesity, and abdominal obesity and related lifestyle factors in young Korean adults. METHODS: The analysis focused on adults aged 19-39 years using data from the Korea National Health and Nutrition Examination Survey (KNHANES) I-V (1998-2012). Underweight was defined as body mass index (BMI) <18.5kg/m(2); obesity as BMI≥30kg/m(2); and abdominal obesity as waist circumference ≥90cm in men and ≥85cm in women...
May 5, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28455224/comparison-of-anthropometric-measurements-associated-with-the-risk-of-endoscopic-erosive-esophagitis-a-cross-sectional-study
#6
Jae Keun Park, Yaeji Lim, Hyuk Lee, Tae Jun Kim, Yoon-Ho Choi, Yang Won Min, Byung-Hoon Min, Jun Haeng Lee, Poong-Lyul Rhee, Jae J Kim
BACKGROUND: In this cross-sectional study, we assessed five anthropometric measurements to determine the most reliable indicator of the erosive esophagitis (EE) risk: body mass index (BMI), waist circumference (WC), waist to height ratio (WHtR), a body shape index (ABSI), and body roundness index (BRI). METHODS: This study included 182,407 participants who underwent an esophagogastroduodenoscopy as part of a routine health check-up. We used the area under the receiver-operating characteristic curve (AUC) to assess the discriminatory power of each anthropometric measure as an indicator of EE risk...
April 25, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28442280/kidney-disease-in-patients-with-obesity-it-is-not-always-obesity-related-glomerulopathy-alone
#7
Steven P Salvatore, James M Chevalier, Sheng F Kuo, Pat F Audia, Surya V Seshan
OBJECTIVE: Patients with obesity are at risk for chronic kidney disease. The aim is to characterize the spectrum of kidney disease in these patients, which may be related to obesity, termed obesity-related glomerulopathy (ORG), or may have other diseases secondary to associated or unassociated medical conditions. METHODS: Native kidney biopsies from 2000 to 2012 were retrospectively reviewed from all patients with body mass index >30kg/m(2). Glomerular diameter was measured using a standard micrometer and clinicopathologic characteristics were analyzed...
April 22, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28420589/associations-between-language-acculturation-age-of-immigration-and-obesity-in-the-mexican-american-mano-a-mano-cohort
#8
Matthew Chrisman, Wong-Ho Chow, Carrie R Daniel, Xifeng Wu, Hua Zhao
INTRODUCTION: As Mexican immigrants to the U.S. become acculturated, they face worsening health outcomes such as obesity. The role of language acculturation in the development of obesity has not been thoroughly examined. METHODS: To examine associations between language acculturation and obesity, data were drawn from the Mexican-American Mano A Mano cohort study. Participants aged 20 years and over (n=18,298) completed baseline questionnaires on socio-demographic and behavioural factors, including physical activity and sitting time...
April 15, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28420588/comparison-of-an-electronic-versus-traditional-food-diary-for-assessing-dietary-intake-a-validation-study
#9
Nicholas R Fuller, Mackenzie Fong, James Gerofi, Fatima Ferkh, Chloris Leung, Lisa Leung, Shaoyu Zhang, Michael Skilton, Ian D Caterson
BACKGROUND: Paper-based estimated food diaries are often used in research to collect dietary data, despite this method being burdensome for both participants and researchers. Such food diaries are often time consuming, labour intensive, and rely on participant literacy and therefore may lead to greater rates of under-reporting. METHODS: This study assessed the validity of the 'Boden Food Plate', a novel web-based electronic application, compared to a paper-based three-day estimated food diary...
April 15, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28416385/abdominal-adiposity-and-low-physical-activity-are-independently-and-inversely-associated-with-bone-mineral-density
#10
Chandramouli Krishnan, Palak Choksi, Mark D Peterson
BACKGROUND AND METHODS: Obesity is a highly heterogeneous condition, and the link between adiposity distribution profiles and skeletal health is not well understood. This study examined the association between adiposity and bone mineral density (BMD) in a large cohort (5268 individuals) of US adults aged 20-85 years. RESULTS: Body mass index (BMI) and moderate-to-vigorous physical activity were positively associated with BMD. Conversely, abdominal adiposity was negatively associated with BMD, even after adjusting for age, race, BMI, and objectively-measured physical activity...
April 14, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28411022/the-prevalence-of-obesity-and-metabolic-syndrome-in-tibetan-immigrants-living-in-high-altitude-areas-in-ladakh-india
#11
Belle Yanyu Lin, Karma Genden, Wei Shen, Po-Shu Wu, Wen-Chien Yang, Hui-Fang Hung, Chun-Min Fu, Kuen-Cheh Yang
OBJECTIVE: To examine the prevalence of obesity and related cardiovascular disease risk factors among Tibetan immigrants living in high altitude areas. RESEARCH METHODS & PROCEDURES: A total of 149 Tibetan immigrants aged 20 years and over were recruited in 2016 in Ladakh, India. Anthropometric indices and biochemical factors were measured. Using the provided Asia-Pacific criteria from the World Health Organization, overweight and obese status were determined. Metabolic syndrome (MetS) was defined according to the American Heart Association...
April 12, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28392264/effects-of-bodypump-and-resistance-training-with-and-without-a-personal-trainer-on-muscle-strength-and-body-composition-in-overweight-and-obese-women-a-randomised-controlled-trial
#12
Anne Mette Rustaden, Lene A H Haakstad, Gøran Paulsen, Kari Bø
OBJECTIVES: Overweight and obese individuals are recommended to perform regular resistance training, and the health- and fitness industry offer several exercise programs with purpose to improve muscle strength and body composition. This randomised controlled trial aimed to compare 12 weeks (45-60min, 3 sessions/weeks) of popular exercise programs, available at health- and fitness centers worldwide. METHODS: Previous untrained women with BMI≥25 were allocated to either BodyPump (a high-repetition group session) (n=25), individual resistance training with a personal trainer (n=25), non-supervised individual resistance training (n=21) and non-exercising control group (n=21)...
April 6, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28389205/accuracy-of-using-self-reported-data-to-screen-children-and-adolescents-for-overweight-and-obesity-status-a-diagnostic-meta-analysis
#13
REVIEW
Jinbo He, Zhihui Cai, Xitao Fan
OBJECTIVE: To estimate the accuracy of using the self-reported body mass index (BMIsr) for screening children and adolescents for overweight and obesity status by quantitatively synthesizing individual studies in the research literature. METHOD: Three databases, namely PubMed, Web of Science, and EBSCOhost were searched up to September 2016. Studies were included that collected both the self-reported data (BMIsr) and direct measurement data (i.e., BMI based on measured height and weight, BMIm) to screen children and adolescents for overweight and obesity status, and provided sufficient data on sensitivity and specificity...
April 4, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28385559/outcome-in-terms-of-percentage-excess-body-weight-loss-ebwl-after-weight-loss-surgery-experience-of-a-large-volume-centre
#14
LETTER
Vittal S R Rao, Mark Peter, Rupa Sarkar, E Salim, Prashant K Jain
No abstract text is available yet for this article.
April 3, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28363705/relationship-between-plasma-adropin-levels-and-body-composition-and-lipid-characteristics-amongst-young-adolescents-in-taiwan
#15
Jin-Biou Chang, Nain-Feng Chu, Fu-Huang Lin, Jhu-Ting Hsu, Pi-Yun Chen
Adropin is a 76 amino acid peptide hormone with a molecular weight of 4999.9Da that may be associated with energy homeostasis, insulin resistance and lipid metabolism in mice and human. There is only a few studies that examine plasma adropin levels and body composition in children. This study is to evaluate the relationship between plasma adropin levels, body composition and lipid variables amongst young adolescents in Taiwan. We examined 492 adolescents (269 females and 223 males) ranging from 12 to 15 years old, with a mean age of 13...
March 28, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28320596/phillyrin-lowers-body-weight-in-obese-mice-via-the-modulation-of-ppar-beta-delta-angptl-4-pathway
#16
Hong-Bo Xiao, Guo-Guang Sui, Xiang-Yang Lu
OBJECTIVE: Previous investigations have shown that the peroxisome proliferator activated receptor beta/delta (PPAR<beta>/<delta>)-angiopoietin-like protein 4 (ANGPTL4) pathways may be a new pharmacologic target for treatment of obesity. The present study was conducted to test the effect of phillyrin, ‎a glucoside, on obesity in mice. METHOD: Fifty mice were randomly divided into 5 groups (n=10): control group (C57BL/6J mice), obese mice group, two groups of obese mice treated with phillyrin (15 or 45mg/kg/day), one group of obese mice treated with PPAR<beta>/<delta> agonist GW0742 (3mg/kg/day)...
March 17, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28285960/weight-reduction-via-life-style-modifications-results-in-reverse-remodelling-and-cardiac-functional-improvement-in-a-patient-with-obesity
#17
Chang Hou, Bo Zheng, Ying Yang, Xin-Gang Wang, Bin Zhang, Qiu-Ping Shi, Ming Chen
The prevalence of obesity has increased strikingly in recent years. Obesity is associated with increased left ventricular end-diastolic dimension (LVEDD), ventricular wall thickness, left ventricular (LV) mass, left atrial diameter, subtle myocardial systolic as well as diastolic dysfunction and has been identified as an independent predictor of these changes. It's convinced that weight reduction results in cardiac reverse remodelling, while the functional changes after weight reduction are variable. Here, we present a recent case of man with moderate obesity who acquires favourable regression in chamber size, wall thickness and significant improvement in cardiac function...
March 9, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/27889357/the-impact-of-overweight-obesity-duration-and-physical-activity-on-telomere-length-an-application-of-the-watch-paradigm
#18
Scott J Dankel, Jeremy P Loenneke, Paul D Loprinzi
INTRODUCTION: Physical activity may protect against health consequences associated with obesity, yet less is known on how the duration of obesity alters this association, specifically as it relates to leukocyte telomere length. METHODS: The 1999-2002 NHANES was used to place individuals into 6 mutually exclusive groups based on physical activity status and weight status/duration. RESULTS: All active individuals, except for those overweight/obese for longer durations, were associated with longer telomeres in comparison to sedentary individuals...
March 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/27773644/does-weight-cycling-promote-obesity-and-metabolic-risk-factors
#19
REVIEW
Grace M Mackie, Dorit Samocha-Bonet, Charmaine S Tam
BACKGROUND: There remains common belief in the general community that weight cycling or 'yo-yo dieting' is associated with potential adverse effects on obesity and metabolic risk factors. In 1994, a review by the National Task Force on the Prevention and Treatment of Obesity concluded that weight cycling did not impact metabolism, and that weight loss attempts should not be discouraged. This study is an updated review of the literature published since 1994, to determine if weight cycling is associated with metabolic risk factors for obesity and type 2 diabetes...
March 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/27665122/whole-exome-sequencing-identifies-a-homozygous-nonsense-variation-in-alms1-gene-in-a-patient-with-syndromic-obesity
#20
Aneek Das Bhowmik, Neerja Gupta, Ashwin Dalal, Madhulika Kabra
In the present study we report on genetic analysis in a patient with developmental delay, truncal obesity and vision problem, to find the causative mutation. Whole exome sequencing was performed on genomic DNA extracted from whole blood of the patient which revealed a homozygous nonsense variant (c.2816T>A) in exon 8 of ALMS1 gene that results in a stop codon and premature truncation at codon 939 (p.L939Ter) of the protein. The mutation was confirmed by Sanger sequencing. Exome sequencing was helpful in establishing diagnosis of Alstrom syndrome in this patient...
March 2017: Obesity Research & Clinical Practice
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