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Obesity Research & Clinical Practice

Azra Ramezankhani, Fereidoun Azizi, Arash Ghanbarian, Donna Parizadeh, Farzad Hadaegh
AIMS: We investigated the association between two hypertriglyceridemic waist (HW) and waist-to height ratio (HWHtR) phenotypes and chronic kidney disease (CKD) using cross sectional and prospective analysis. METHODS: Data of 12,012 individuals (44% men) of the Tehran Lipid and Glucose Study (TLGS) at two phases [(1999-2001) and (2002-2005)], were used for cross-sectional analysis. This population was followed until 2014 with median follow-up 12.4 years (95% confidence interval (CI): 11...
November 23, 2016: Obesity Research & Clinical Practice
Scott J Dankel, Jeremy P Loenneke, Paul D Loprinzi
INTRODUCTION: Physical activity may protect against health consequences associated with obesity, yet less is known on how the duration of obesity alters this association, specifically as it relates to leukocyte telomere length. METHODS: The 1999-2002 NHANES was used to place individuals into 6 mutually exclusive groups based on physical activity status and weight status/duration. RESULTS: All active individuals, except for those overweight/obese for longer durations, were associated with longer telomeres in comparison to sedentary individuals...
November 23, 2016: Obesity Research & Clinical Practice
Sandra Kaltner, Anja Schulz, Petra Jansen
Obesity has been related to deficient mental rotation performance. We assessed object-based and egocentric MR tasks in 19 obese and 19 normal-weight participants. Results showed slower response times of obese adolescents only for high angular disparities. This finding might emerge because of impairments in working memory, motor skills or perspective taking processes in obese youth.
November 22, 2016: Obesity Research & Clinical Practice
Alyssa B Dufour, Elena Losina, Hylton B Menz, Michael P LaValley, Marian T Hannan
OBJECTIVE: We investigated obesity, foot pain and selected foot disorders, and determined if associations differed by foot posture or dynamic foot function. METHODS: We included 2445 men and women (4888 feet) from the Framingham Foot Study (2002-2008). A foot examination assessed presence of disorders and pain on each foot. Body mass index (BMI, kg/m(2)) was categorized as normal (<25), overweight (25-29.99), moderate-obesity (30-34.99) severe-obesity (35+). Foot posture (normal, cavus, planus) and dynamic foot function (normal, supinated, pronated) were defined using plantar pressure measurement system...
November 22, 2016: Obesity Research & Clinical Practice
Dustin T Duncan, Andrew R Hansen, Jennifer Woo Baidal, Rodney Lyn, Ashley Hill, Jian Zhang
BACKGROUND: Excess body weight has been reported to be associated with excessive school absenteeism (ESA), but less is known about the association with perceived body weight. The study objective was to weigh the relative influence of perceived and measured weight status on school attendance. METHODS: We used the data from 3113 adolescents age 12-19 years who were interviewed as a part of the National Health and Nutrition Examination Surveys (NHANES), 2003-2008. Body weight and height were measured during the physical examination, while self-perceived body weight and the number of school days missed was assessed using questionnaires...
November 7, 2016: Obesity Research & Clinical Practice
Andrea T Kozak, Jessica Davis, Ryan Brown, Matthew Grabowski
OBJECTIVE: Low distress tolerance (DT) is an inability to handle negative emotions. There is strong support for the connection between low DT and substance addiction, which suggests that the former might be related to food addiction (FA). Previous work found that low DT was related to overeating in a college sample. The current study had two primary aims: (1) to determine whether low DT is associated with overeating in a sample of participants with diverse races and incomes, and (2) to investigate the relationships among DT and body mass index (BMI) as well as DT and FA symptoms...
October 25, 2016: Obesity Research & Clinical Practice
Jasmine Dhaliwal, Arnaldo J Perez, Nicholas L Holt, Rebecca Gokiert, Jean-Pierre Chanoine, Katherine M Morrison, Laurent Legault, Arya M Sharma, Geoff D C Ball
OBJECTIVE: To explore parents' reasons for discontinuing tertiary-level care for paediatric weight management. METHODS: Participants were parents of 10-17year olds (body mass index [BMI] ≥85th percentile) who were referred for paediatric weight management. Parents were recruited from three Canadian sites (Vancouver, BC; Edmonton, AB; Hamilton, ON) and were eligible if their children attended at least one clinical appointment and subsequently discontinued care...
October 24, 2016: Obesity Research & Clinical Practice
Daniel A Enquobahrie, Pandora L Wander, Mahlet G Tadesse, Chunfang Qiu, Claudia Holzman, Michelle A Williams
BACKGROUND: Maternal pre-pregnancy overweight and obese status has been associated with a number of pregnancy complications and adverse offspring outcomes. Mechanisms for observed associations, however, are largely unknown. We investigated associations of pre-pregnancy body mass index with early-mid pregnancy epigenetic biomarkers, circulating microRNAs. METHODS: Peripheral blood was collected from participants (16-27 weeks gestation) of two multi-racial pregnancy cohorts, the Omega Study and the Pregnancy Outcomes and Community Health Study...
October 24, 2016: Obesity Research & Clinical Practice
Grace M Mackie, Dorit Samocha-Bonet, Charmaine S Tam
BACKGROUND: There remains common belief in the general community that weight cycling or 'yo-yo dieting' is associated with potential adverse effects on obesity and metabolic risk factors. In 1994, a review by the National Task Force on the Prevention and Treatment of Obesity concluded that weight cycling did not impact metabolism, and that weight loss attempts should not be discouraged. This study is an updated review of the literature published since 1994, to determine if weight cycling is associated with metabolic risk factors for obesity and type 2 diabetes...
October 20, 2016: Obesity Research & Clinical Practice
Sintip Pattanakuhar, Anchalee Pongchaidecha, Nipon Chattipakorn, Siriporn C Chattipakorn
Skeletal muscles play important roles in metabolism, energy expenditure, physical strength, and locomotive activity. Skeletal muscle fibre types in the body are heterogeneous. They can be classified as oxidative types and glycolytic types with oxidative-type are fatigue-resistant and use oxidative metabolism, while fibres with glycolytic-type are fatigue-sensitive and prefer glycolytic metabolism. Several studies demonstrated that an obese condition with abnormal metabolic parameters has been negatively correlated with the distribution of oxidative-type skeletal muscle fibres, but positively associated with that of glycolytic-type muscle fibres...
October 15, 2016: Obesity Research & Clinical Practice
Ingrid S K Krishnadath, Jerry R Toelsie, Lenny Nahar-van Venrooij, Albert Hofman, Vincent W V Jaddoe
BACKGROUND: Sex-specific body mass index (BMI) and waist circumference (WC) cut-off values have been validated for a limited number of ethnic groups. We aimed to derive these cut-off values for Amerindians, Creoles, Hindustani, Javanese, Maroons and Mixed living in Suriname. METHODS: Data from individuals aged 20-65, in the Suriname Health Study was used to derive optimal cut-off values for BMI and WC for the prediction of hypertension (n=4910) and cardio-metabolic risk (n=2924)...
October 6, 2016: Obesity Research & Clinical Practice
Sune Dandanell, Camilla Skovborg, Charlotte Boslev Præst, Kasper Bøgh Kristensen, Malene Glerup Nielsen, Sofie Lionett, Sofie Drevsholt Jørgensen, Andreas Vigelsø, Flemming Dela, Jørn Wulff Helge
OBJECTIVE: Intensive lifestyle interventions (ILI) are criticised for ineffective obesity treatment because weight loss over time is modest and thus of limited clinical relevance. However, a subgroup (5-30%) maintains a clinical weight loss >10%, but it is not clear if cardiometabolic health follows this pattern. The aim was to study the effect of different magnitudes of weight loss maintenance after ILI on cardiometabolic health. METHODS: Eighty out of 2420 former participants (age: 36±1, BMI: 38±1, (means ±SE)) in an 11-12-week ILI were recruited into 3 groups; clinical weight loss maintenance (>10% weight loss), moderate maintenance (1-10%), and weight regain based on weight loss at follow-up (5...
October 5, 2016: Obesity Research & Clinical Practice
Jared M Tucker, Kathleen Howard, Emily H Guseman, Kimbo E Yee, Heather Saturley, Joey C Eisenmann
BACKGROUND: The Family Nutrition and Physical Activity Screening Tool (FNPA) evaluates family behavioural and environmental factors associated with pediatric obesity, but it is unknown if FNPA scores differ among youth across obesity severities. Our aim was to determine the association between the FNPA and obesity severity in youth referred to weight management. METHODS: Upon initiating treatment, height, weight, and the FNPA were collected according to standard procedures...
October 4, 2016: Obesity Research & Clinical Practice
Salman Waheed, Buddhadeb Dawn, Kamal Gupta
BACKGROUND: Both QT interval and body mass index (BMI) are independently associated with mortality. Those with higher BMI have longer QT, although evidence is inconsistent. The joint association of QT and BMI with mortality merits investigation. OBJECTIVE: To examine the association of QT with BMI, and to examine the joint association of QT and BMI with all-cause and cardiovascular mortality. METHODS: We followed 4036 participants from NHANES III for a median of 14...
September 23, 2016: Obesity Research & Clinical Practice
Aneek Das Bhowmik, Neerja Gupta, Ashwin Dalal, Madhulika Kabra
In the present study we report on genetic analysis in a patient with developmental delay, truncal obesity and vision problem, to find the causative mutation. Whole exome sequencing was performed on genomic DNA extracted from whole blood of the patient which revealed a homozygous nonsense variant (c.2816T>A) in exon 8 of ALMS1 gene that results in a stop codon and premature truncation at codon 939 (p.L939Ter) of the protein. The mutation was confirmed by Sanger sequencing. Exome sequencing was helpful in establishing diagnosis of Alstrom syndrome in this patient...
September 21, 2016: Obesity Research & Clinical Practice
Alexis Ruffault, Sébastien Czernichow, Martin S Hagger, Margot Ferrand, Nelly Erichot, Claire Carette, Emilie Boujut, Cécile Flahault
The aim of this study was to conduct a comprehensive quantitative synthesis of the effects of mindfulness training interventions on weight-loss and health behaviours in adults with overweight and obesity using meta-analytic techniques. Studies included in the analysis (k=12) were randomised controlled trials investigating the effects of any form of mindfulness training on weight loss, impulsive eating, binge eating, or physical activity participation in adults with overweight and obesity. Random effects meta-analysis revealed that mindfulness training had no significant effect on weight loss, but an overall negative effect on impulsive eating (d=-1...
September 19, 2016: Obesity Research & Clinical Practice
Andrea De Lorenzo, Leticia Glerian, Ana Carolina Amaral, Thiago B Reis, Ronaldo S L Lima
OBJECTIVE: To evaluate the prevalence of the "metabolically healthy" (MH) or "metabolically unhealthy" (MU) obesity phenotypes and their association with cardiorespiratory fitness and inducible myocardial ischaemia. METHODS: Individuals without known coronary artery disease undergoing myocardial perfusion single-photon emission computed tomography (MPS) were studied. Those without dyslipidemia, hypertension, or diabetes were considered MH, and when ≥1 of these was present, MU status was considered present...
September 13, 2016: Obesity Research & Clinical Practice
Supa Pengpid, Karl Peltzer
OBJECTIVE: Concern about overweight and obesity is growing worldwide, and more research to examine behaviours associated with the risk for increased weight in adult populations is needed. The aim of this study was to estimate associations between behavioural risk factors and overweight and obesity among adults in nationally representative population samples from 20 countries in Europe, 8 countries in Asia, Australia, Chile and USA. METHODS: This secondary analysis is based on the International Social Survey Program (ISSP), 2011-2013, Health and Health Care Module...
September 7, 2016: Obesity Research & Clinical Practice
Güzin Mukaddes Sevinçer, Gökben Hızlı Sayar
Sleep-related eating disorder (SRED) is a parasomnia characterised by recurrent episodes of eating after arousal from sleep, occurring in an unconscious and involuntary manner. It has been reported mainly in association with the use of psychotropic medications. This case report is of a patient diagnosed with a sleep-related eating disorder associated with amnesia in the postoperative period following bariatric surgery. Such eating episodes without awareness in postoperative period might have devastating results by disturbing compliance with suggested eating behaviours...
September 7, 2016: Obesity Research & Clinical Practice
Sebastian Barth, Michael Zacher, Holger Reinecke, Martina B Hautmann, Sebastian Kerber, Frank Gietzen, Philipp Halbfass, Anja Schade, Thomas Deneke, Bernhard Schieffer, Karsten Hamm
AIM: The aim of our comprehensive single centre analysis was to evaluate the incidence of coronary heart disease (CHD) in extremely obese patients. METHODS AND RESULTS: Between 2005 and 2015 we investigated retrospectively 23,359 patients undergoing cardiac catheterisation in our institution. Patients were divided in six weight classes according to World Health Organization (WHO) criteria [1] (WHO, 2000). Cardiovascular risk factors, comorbidities, CCS stadium [2] (Cox and Naylor, 1992) and NYHA functional class [3] (The Criteria Committee of the New York Heart Association, 1994) were retrieved from electronic patient records...
September 6, 2016: Obesity Research & Clinical Practice
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