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IET Nanobiotechnology

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https://www.readbyqxmd.com/read/29155407/synthesis-of-porous-gdf3-er-3-yb-3-cooh-core-shell-structured-bi-functional-nanoparticles-for-drug-delivery
#1
Hongxia Peng, Ouyang Jundai, Jin Wen, Yangxi Peng
The authors synthesised porous GdF3:Er(3+),Yb(3+)-COOH core-shell structured bi-functional nanoparticles through a one-step hydrothermal route during which ethylene diamine tetraacetic acid) was bound to the surface of the nanoparticles. It has high up-conversion emission intensity for monitoring the drug release process and magnetisation saturation value (10.2 emu/g) for drug targeting under foreign magnetic fields. Moreover, porous GdF3:Er(3+),Yb(3+) as drug carriers with a high drug-loading efficiency...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155406/biocompatible-antimicrobial-cotton-fibres-for-healthcare-industries-a-biogenic-approach-for-synthesis-of-bio-organic-coated-silver-nanoparticles
#2
Sahebrao B Kashid, Jaya R Lakkakula, Deepak S Chauhan, Rohit Srivastava, Rajesh W Raut
Cotton fibres coated with biogenically fabricated silver nanoparticles (SNPs) are most sought material because of their enhanced activity and biocompatibility. After successful synthesis of SNPs on cotton fibres using leaf extract of Vitex negundo Linn, the fibres were studied using diffuse reflectance spectroscopy, scanning electron microscopy, nanoparticle tracking analysis, energy dispersive X-ray, and inductively coupled plasma atomic emission spectrometry. The characterisation revealed uniformly distributed spherical agglomerates of SNPs having individual particle size around 50 nm with the deposition load of 423 μg of silver per gram of cotton...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155405/kinnow-peel-extract-as-a-reducing-and-capping-agent-for-the-fabrication-of-silver-nps-and-their-biological-applications
#3
Sania Naz, Fahad Shams, Saira Tabassum, Ihsan Ul-Haq, Muhammad Ashraf, Muhammad Zia
An effective approach used for the synthesis of silver nanoparticles (AgNPs) through green chemistry by using Kinnow peel extract as a reducing and capping agent is presented. Two different approaches, diluted and concentrated peel extracts, were used for the synthesis of AgNPs. Ultraviolet-visible spectroscopy exhibits characteristic absorption peaks at 425 and 400 nm for nanoparticles (NPs) synthesised by diluted and concentrated extracts, respectively. The X-ray diffraction analysis of nanofabricated silver exhibited a pure face centred cubic structure of 27...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155404/carbohydrate-source-affects-the-synthesis-of-silver-nanoparticles-by-lactobacillus-plantarum-1449-and-lactobacillus-ruminis-1313
#4
María de Lourdes Reyes-Escogido, David Meneses-Rodríguez, Rodolfo Guardado-Mendoza
Strains of Lactobacillus have been used for the synthesis of metallic nanoparticles. Since the carbohydrate source could influence the yield and size of the synthesised nanoparticles, the authors evaluated the potential of Lactobacillus plantarum 1449 and Lactobacillus ruminis 1313 to produce silver nanoparticles (AgNPs) using three carbohydrate sources and AgNO3. The presence of AgNO3 in the medium extended the duration of the acceleration and logarithmic phases of the two strains independently of the carbohydrate source used but did not inhibit their growth...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155403/phyto-assisted-synthesis-of-bio-functionalised-silver-nanoparticles-and-their-potential-anti-oxidant-anti-microbial-and-wound-healing-activities
#5
Yugal Kishore Mohanta, Kunal Biswas, Sujogya Kumar Panda, Jaya Bandyopadhyay, Debashis De, Rasu Jayabalan, Akshaya Kumar Bastia, Tapan Kumar Mohanta
Bio- synthesis of silver nanoparticles (AgNPs) was made by using the aqueous leaf extract of Ardisia solanacea. Rapid formation of AgNPs was observed from silver nitrate upon treatment with the aqueous extract of A. solanacea leaf. The formation and stability of the AgNPs in the colloidal solution were monitored by UV-visible spectrophotometer. The mean particle diameter of AgNPs was calculated from the DLS with an average size ∼4 nm and ∼65 nm. ATR-FTIR spectroscopy confirmed the presence of alcohols, aldehydes, flavonoids, phenols and nitro compounds in the leaf which act as the stabilizing agent...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155402/synthesis-of-silver-nanoparticles-from-a-desmodium-adscendens-extract-and-its-antibacterial-evaluation-on-wound-dressing-material
#6
Jaya R Lakkakula, Derek Tantoh Ndinteh, Sandy F van Vuuren, Denise K Olivier, Rui W M Krause
The one-pot synthesis of silver nanoparticles (AgNPs) using the medium-polar extract of Desmodium adscendens (Sw.) DC. is presented here as an alternative synthesis of metal NPs. Characterisation of the formed NPs showed polydispersed AgNPs ranging from 15 to 100 nm where the concentration of metal ions was found to play a role in the size and shape of the prepared NPs. It could be established that the flavonoids, saponins, and alkaloids present in the extract acted as both reducing and stabilising agents during the formation of the capped metal NPs...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155401/reconstructing-phylogenetic-tree-using-a-protein-protein-interaction-technique
#7
Shamita Malik, Dolly Sharma, Sunil Kumar Khatri
In this study, a novel substitution method for finding potential protein-protein interactions (PPIs) has been discussed. This newly designed method for analyzing PPI also aids in the comparison of evolutionary distances. The method deals with various data sets, and additionally performs measurable assessment to determine PPIs is introduced. PPIs are biologically relevant and aid in better conceptual framework of phylogenetic profiling. The newly designed framework gives vision to relate the topological properties of the system with evolutionary behavior of datasets...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155400/co-condensation-synthesis-of-well-defined-mesoporous-silica-nanoparticles-effect-of-surface-chemical-modification-on-plasmid-dna-condensation-and-transfection
#8
Mahdokht Mahmoodi, Abbas Behzad-Behbahani, Sadigheh Sharifzadeh, Samira Sadat Abolmaali, AliMohammad Tamaddon
Chemically modified mesoporous silica nanoparticles (MSNs) are of interest due to their chemical and thermal stability with adjustable morphology and porosity; therefore, it was aimed to develop and compare the MCM-41 MSNs functionalised with imidazole groups (MCM-41-Im) to unmodified (MCM-41-OH) and primary amine functionalised (MCM-41-NH2) MSNs for experimental gene delivery. The results show efficient transfection of the complexes of the plasmid and either MCM-41-NH2 or MCM-41-Im. Furthermore, following transfection of HeLa cells using MCM-41-Im, an enhanced GFP expression was achieved consistent with the noticeable DNase1 protection and endosomal escape properties of MCM-41-Im using carboxyfluorescein tracer...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155399/green-synthesis-of-anisotropic-gold-nanoparticles-using-hordenine-and-their-antibiofilm-efficacy-against-pseudomonas-aeruginosa
#9
Jobina Rajkumari, Himani Meena, Muralitharan Gangatharan, Siddhardha Busi
Pseudomonas aeruginosa is a notorious pathogen that causes biofilm aided infections in patients with cystic fibrosis and burn wounds, resulting in significant mortality in immunocompromised individuals. This study reports a novel one-step biosynthesis of gold nanoparticles using phytocompound, hordenine (HD), as a reducing and capping agent. The synthesis of the anisotropic hordenine-fabricated gold nanoparticles (HD-AuNPs) with an average particle size of 136.87 nm was achieved within 12 h of incubation at room temperature...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155398/investigation-of-graphene-on-metal-substrates-for-spr-based-sensor-using-finite-difference-time-domain
#10
Fairus Atida Said, Pulliyaseri Susthitha Menon, Venkatachalam Rajendran, Sahbudin Shaari, Burhanuddin Y Majlis
In this study, the authors investigated the effects of a single layer graphene as a coating layer on top of metal thin films such as silver, gold, aluminum and copper using finite-difference time domain method. To enhance the resolution of surface plasmon resonance (SPR) sensor, it is necessary to increase the SPR reflectivity and decrease the full-width-half maximum (FWHM) of the SPR curve so that there is minimum uncertainty in the determination of the resonance dip. Numerical data was verified with analytical and experimental data where all the data were in good agreement with resonance angle differing in <10% due to noise present in components such as humidity and temperature...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155397/facile-phyto-mediated-synthesis-of-silver-nanoparticles-using-chinese-winter-jujube-ziziphus-jujuba-mill-cv-dongzao-extract-and-their-antibacterial-catalytic-properties
#11
Chun-Gang Yuan, Can Huo, Bing Gui, Jing-Fu Liu, Yong-Sheng Chen
The aqueous extract of Chinese winter jujube (Ziziphus jujuba Mill. cv. Dongzao) was used as reducing and capping agents for the synthesis of silver nanoparticles (AgNPs) for the first time. The resulting AgNPs were characterised by UV/Visible (UV-Vis) spectroscopy, atomic force microscope, transmission electron microscopy, selected area electron diffraction, X-ray diffraction, scanning electron microscopy, energy-dispersive X-ray and Fourier transform infrared spectroscopy (FTIR). The colloidal solution of AgNPs gave a maximum UV-Vis absorbance at 446 nm...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155396/biomimetic-synthesis-of-silver-nanoparticles-from-streptomyces-atrovirens-and-their-potential-anticancer-activity-against-human-breast-cancer-cells
#12
Ramasamy Subbaiya, Muthupandian Saravanan, Andavar Raja Priya, Konathala Ravi Shankar, Masilamani Selvam, Muhammad Ovais, Ramachandran Balajee, Hamed Barabadi
Silver nanoparticles (AgNPs) have been undeniable for its antimicrobial activity while its antitumour potential is still limited. Therefore, the present study focused on determining cytotoxic effects of AgNPs on Michigan cancer foundation-7 (MCF-7) breast cancer cells and its corresponding mechanism of cell death. Herein, the authors developed a bio-reduction method for AgNPs synthesis using actinomycetes isolated from marine soil sample. The isolated strain was identified by 16s ribotyping method and it was found to be Streptomyces atrovirens...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155395/porcine-skin-gelatin-silver-nanocomposites-synthesis-characterisation-cell-cytotoxicity-and-antibacterial-properties
#13
Hosam I Salaheldin, Amr Negm, Gamal E H Osman
Silver nanoparticles (AgNPs) were synthesised with hydrothermal autoclaving technique by using AgNO3 salt (silver precursor) at different concentrations (0.01, 0.1, 0.55, 1.1, 5.5, and 11 mM) and porcine skin (1% (w/v) ) gelatin polymeric matrix (reducing and stabiliser agent). The reaction was performed in an autoclave at 103 kPa and 121°C and the hydrothermal autoclaving exposure time and AgNO3 molar concentration were varied at a constant porcine skin gelatin concentration. The as-prepared AgNPs were characterised by UV-visible spectroscopy, transmission electron microscopy, and Fourier transform infrared spectroscopy...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155394/label-free-and-dynamic-monitoring-of-cytotoxicity-to-the-blood-brain-barrier-cells-treated-with-nanometre-copper-oxide
#14
Duan Lian, Zhang Chonghua, Gu Wen, Zhang Hongwei, Bai Xuetao
A cytotoxicity study was conducted with a primary culture of the nervous system cells, including brain microvascular endothelial cells (BMECs) and astrocytes, which are important components of the blood-brain barrier. The real-time cell analysis (RTCA) was used to determine the cytotoxicity of copper-oxide nanoparticles (CuO NPs). The IC50 values of CuO NPs in astrocytes and BMECs were determined by the RTCA at different exposure times and were used as base values for further research. DNA damage after exposure to CuO NPs for 3 and 24 h was assessed using comet assay at the IC50 obtained from RTCA...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155393/enhanced-antibacterial-effect-of-azlocillin-in-conjugation-with-silver-nanoparticles-against-pseudomonas-aeruginosa
#15
Aram Alizadeh, Mojtaba Salouti, Hamed Alizadeh, Ali Reza Kazemizadeh, Ali Asghar Safari, Sanaz Mahmazi
In recent years, the problems associated with bacterial resistance to antibiotics caused nanodrugs to be considered as a new way for infectious diseases treatment. The main purpose of this study was to develop a new agent against Pseudomonas aeruginosa, a very difficult bacterium to treat, based on azlocillin antibiotic and silver nanoparticles (AgNPs). Azlocillin was conjugated with AgNPs by chemical methods and its antimicrobial activity was studied against P. aeruginosa using well diffusion agar method. Then, minimum inhibitory concentration and minimum bactericidal concentration of the new conjugate was specified with macro-dilution method...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155392/green-synthesised-zinc-oxide-nanostructures-through-periploca-aphylla-extract-shows-tremendous-antibacterial-potential-against-multidrug-resistant-pathogens
#16
Fazal Abbas, Qaisar Maqbool, Mudassar Nazar, Nyla Jabeen, Syed Zaheer Hussain, Sadaf Anwaar, Nasir Mehmood, Muhammad Saleem Sheikh, Talib Hussain, Sidra Iftikhar
To grapple with multidrug resistant bacterial infections, implementations of antibacterial nanomedicines have gained prime attention of the researchers across the globe. Nowadays, zinc oxide (ZnO) at nano-scale has emerged as a promising antibacterial therapeutic agent. Keeping this in view, ZnO nanostructures (ZnO-NS) have been synthesised through reduction by P. aphylla aqueous extract without the utilisation of any acid or base. Structural examinations via scanning electron microscopy (SEM) and X-ray diffraction have revealed pure phase morphology with highly homogenised average particle size of 18 nm...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155391/facile-synthesis-of-reduced-graphene-oxide-trimethyl-chlorosilane-coated-cellulose-nanofibres-aerogel-for-oil-absorption
#17
Zhaoyang Xu, Huan Zhou, Xiangdong Jiang, Jianyu Li, Fang Huang
A hydrophobic and oleophilic trimethyl chlorosilane/reduced graphene oxide-coated cellulose nanofibres (TMCS/rGO/CNFs) aerogel with a three-dimensional structure was fabricated through a facile dip-coating process. The prepared aerogel exhibited several advantageous properties for absorption and expulsion of oils from water surfaces, such as a high specific surface area, low density (6.78 mg/cm(3)) and good porosity (99.12%). In addition, the TMCS/rGO/CNFs aerogel demonstrated good absorption capacities up to 39 times its own weight over a short time (1...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155390/biosynthesised-silver-and-copper-nanoformulation-as-foliar-spray-to-control-bird-s-eye-spot-disease-in-tea-plantations
#18
Balasubramanian Mythili Gnanamangai, Ponnusamy Ponmurugan, Sengottaiyan Eashwari Jeeva, Kolandasamy Manjukarunambika, Vishwanathan Elango, Kolandaivel Hemalatha, Jyoti Prasad Kakati, Rajamanickam Mohanraj, Somasundaram Prathap
Tea leaves have economic importance in preparation of the popular beverage of the world "tea". Bird's eye spot disease of tea leaves creates significant revenue loss in tea trade of many tea plant cultivating countries. Management of this disease by silver (AgNps) and copper (CuNps) nanoparticles that are biosynthesised by efficient antagonists was studied. The biocontrol agents like Pseudomonas fluorescens, Trichoderma atroviride and Streptomyces sannanensis were evaluated for nanoparticle synthesis against Cercospora theae isolates namely KC10, MC24 and VC38...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155389/effect-of-the-polyelectrolyte-coating-on-the-photothermal-efficiency-of-gold-nanorods-and-the-photothermal-induced-cancer-cell-damage
#19
Rashmi Shrivastava, Alok Dube
Coating gold nanorods (GNRs) with polyelectrolytes is an effective approach to make them biocompatible for potential use in photothermal treatment (PTT) of cancer. The authors report the effect of coating of the GNRs with polystyrene sulphonate (PSS-GNRs) and PSS plus poly di-allyl di-methyl ammonium chloride (PDDAC-GNRs) on its photothermal conversion efficiency (PTE), cellular uptake and subsequently the photothermal induced cytotoxicity in human oral cancer cells (NT8e). Coating of GNRs with PSS led to decrease in PTE by ∼30% and further coating it with PDDAC led to its increase to similar level, with respect to as- prepared GNRs...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29155388/polyelectrolyte-multilayers-for-bio-applications-recent-advancements
#20
REVIEW
Suman Pahal, Ruchi Gakhar, Ashok M Raichur, Manoj M Varma
The synergistic relationship between structure and the bulk properties of polyelectrolyte multilayer (PEM) films has generated tremendous interest in their application for loading and release of bioactive species. Layer-by-layer assembly is the simplest, cost effective process for fabrication of such PEMs films, leading to one of the most widely accepted platforms for incorporating biological molecules with nanometre precision. The bulk reservoir properties of PEM films render them a potential candidate for applications such as biosensing, drug delivery and tissue engineering...
December 2017: IET Nanobiotechnology
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