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IET Nanobiotechnology

Rajendran Mala, Antony Annie Aglin, Arul Selvaraj Ruby Celsia, Sivalingam Geerthika, Narbahvi Kiruthika, Chinnathambi VazagaPriya, Kumarapillai Srinivasa Kumar
Foley catheters are inevitable in health care unit. Pathogens colonise and form biofilm on catheter causing catheter-associated urinary tract infection. Therefore, the authors aimed to functionalise catheter to resist biofilm formation. The authors impregnated urinary catheters with a synergistic combination of antibiotics and silver nanoparticles (SNPs) to evaluate antibiofilm efficacy in vitro and in vivo. SNPs were synthesised using Spirulina platensis. Synergy between the SNPs and antibiotics was determined by the checker-board method...
August 2017: IET Nanobiotechnology
Mojtaba Salouti, Faranak Saghatchi
Using of targeted contrast agents in X-ray imaging of breast cancer can improve the accuracy of diagnosis, staging, and treatment planning by providing early detection and superior definition of tumour volume. This study demonstrates a new class of X-ray contrast agents based on gold nanoparticles (GNPs) and bombesin (BBN) for imaging of breast cancer in radiology. GNPs were synthesised in spherical shape in the size range of 15 ± 2 nm and conjugated with BBN followed by coating with polyethyleneglycol (PEG)...
August 2017: IET Nanobiotechnology
Ayoub Abdullah Alqadami, Mu Naushad, Mohammad Abulhassan Abdalla, Mohammad Rizwan Khan, Zeid Abdullah Alothman, Saikh Mohammad Wabaidur, Ayman Abdel Ghfar
In this study, the determination of noxious heavy metals, cadmium (Cd), bismuth (Bi), mercury (Hg), titanium (Ti), lead (Pb) and metalloid arsenic (As) in skin-whitening cosmetics were examined using microwave digestion and inductively coupled plasma atomic emission spectrometry method. A complete digestion of cosmetics samples was achieved using a mixture of hydrofluoric acid/hydrogen peroxide/nitric acid. The quantification of the target compounds was done by standard addition method. The excellent quality parameters for instance, detection limits, As (4...
August 2017: IET Nanobiotechnology
Neda Alasvand, Maryam Saeidifar, Ali Akbar Saboury, Masoud Mozafari
Over the past few years, there have been several attempts to deliver anticancer drugs into the body. It has been shown that compared to other available carriers, colloidal gelatin nanoparticles (CGNPs) have distinct properties due to their exceptional physico-chemical and biological characteristics. In this study, a novel water-soluble palladium (II) anticancer complex was first synthesised, and then loaded into CGNPs. The CGNPs were synthesised through a two-step desolvation method with an average particle size of 378 nm...
August 2017: IET Nanobiotechnology
Kapil Punjabi, Snehal Yedurkar, Sejal Doshi, Sunita Deshapnde, Shashikant Vaidya
The aim of this study was to isolate and screen bacteria from soil and effluent of electroplating industries for the synthesis of silver nanoparticles and characterize the potential isolate. Soil and effluent of electroplating industries from Mumbai were screened for bacteria capable of synthesizing silver nanoparticles. From two soils and eight effluent samples 20 bacterial isolates were obtained, of these, one was found to synthesize silver nanoparticles. Synthesis of silver nanoparticle by bacteria was confirmed by undertaking characterization studies of nanoparticles that involved spectroscopy and electron microscopic techniques...
August 2017: IET Nanobiotechnology
Juhi Saxena, Pankaj Sharma, Abhijeet Singh
Biomimetic synthesis of metal nanoparticles (NPs) is safe and eco-friendly; therefore, find diverse applications. Considering this, the soil fungi Penicillium chrysogenum strain Fungal germplasm collection centre/ BLS1 was isolated, characterized and explored to synthesize extracellular silver NPs (AgNPs) under optimised conditions. The synthesis of AgNPs was investigated using ultraviolet (UV)-visible spectroscopy, Fourier-transform infra-red spectroscopy (FTIR), transmission electron microscope (TEM) and dynamic light scattering (DLS) analysis...
August 2017: IET Nanobiotechnology
Raksha Pandit, Swapnil Gaikwad, Mahendra Rai
In the present study, the authors synthesised copper nanoparticles (CuNPs) by using extract of Zingiber officinale (ginger) and later the NPs were bioconjugated with nisin, which shows antimicrobial activity against food spoilage microorganisms. CuNPs and its bioconjugate were characterised by ultraviolet-vis spectroscopy, NP tracking analysis, Zetasizer, transmission electron microscopy analysis, X-ray diffraction and Fourier transform infra-red (FTIR) spectroscopy. Zeta potential of CuNPs and its bioconjugate were found to be very stable...
August 2017: IET Nanobiotechnology
Zhenhao Ding, Hiromichi Kasahara, Michihiko Nakano, Junya Suehiro
In this study, an electrical DNA detection method was applied to bacterial detection. DNA was extracted from bacteria and amplified by polymerase chain reaction. The microbeads were labelled with amplicons, altering their surface conductance and therefore their dielectrophoresis characteristics. Amplicon-labelled microbeads could thus be trapped within a high-strength electric field, where they formed a pearl chain between the electrodes, resulting in an increased conductance between the electrodes. This method reduces the amplicon detection time from 1-2 h to 15 min, compared with the conventional method...
August 2017: IET Nanobiotechnology
Nyla Jabeen, Qaisar Maqbool, Shamaila Sajjad, Anam Minhas, Umer Younas, Sadaf Anwaar, Mudassar Nazar, Rizwan Kausar, Syed Zaheer Hussain
A growing trend within nanomedicine has been the fabrication of self-delivering supramolecular nanomedicines containing a high and fixed drug content ensuring eco-friendly conditions. This study reports on green synthesis of silica nanoparticles (Si-NPs) using Azadirachta indica leaves extract as an effective chelating agent. X-ray diffraction analysis and Fourier transform-infra-red spectroscopic examination were studied. Scanning electron microscopy analysis revealed that the average size of particles formed via plant extract as reducing agent without any surfactant is in the range of 100-170 nm while addition of cetyltrimethyl ammonium bromide were more uniform with 200 nm in size...
August 2017: IET Nanobiotechnology
Carolina A Santos, Victor M Balcão, Marco V Chaud, Marcelo Martins Seckler, Mahendra Rai, Marta M D C Vila
The increasing and alarming panorama of bacterial infections and associated morbidities that occur during medical and hospital procedures makes the development of technologies that aid in controlling such bacterial infections of utmost importance. Recent studies have shown that formulations with metal nanoparticles exhibit good antibacterial properties against a broad spectrum of microorganisms. Moreover, it was demonstrated that some biologically active polymeric materials, when applied in combination with chemical antimicrobial agents, enhance the therapeutic action of the latter...
August 2017: IET Nanobiotechnology
Avinash P Ingle, Mahendra Rai
Flower-shaped copper nanoparticles were synthesised by a green and ecofriendly chemical reduction approach using copper sulphate and cytyltrimethal ammonium bromide. The UV-vis spectrophotometer analysis showed maximum absorption at about 552 nm, which is specifically reported for copper nanoparticles. The crystal lattice structure of copper nanoflowers was confirmed by X-ray diffraction analysis. Further, the transmission electron microscopic studies revealed the flower shape copper nanoparticles in the size range of 100-500 nm...
August 2017: IET Nanobiotechnology
Mahmoud Nasrollahzadeh, S Mohammad Sajadi, Mehdi Maham, Hamid Reza Dasmeh
This study demonstrates a clean, non-toxic and environment friendly synthetic strategy for the preparation of the Natrolite zeolite/Cu nanoparticles (NPs) using Natrolite zeolite as a natural support and Anthemis xylopoda flowers aqueous extract as a reducing and stabilising agent for the synthesis of Cu NPs. Cu NPs with 20 nm diameter were immobilised homogeneously on the surface of Natrolite zeolite. The synthesised Natrolite zeolite/Cu NPs was used as an environmentally benign catalyst for the reduction of 4-nitrophenol, congo red and methylene blue in aqueous media at an ambient temperature...
August 2017: IET Nanobiotechnology
Aradhana Sukhwal, Devendra Jain, Arunabh Joshi, Pokhar Rawal, Himmat S Kushwaha
In the recent decades, nanotechnology is gaining tremendous impetus due to its capability of modulating metals into their nanosize, which drastically changes the chemical, physical, biological and optical properties of metals. In this study, silver nanoparticles (AgNPs) synthesis using aqueous leaf extracts of Tagetes patula L. which act as reducing agent as well as capping agent is reported. Synthesis of AgNPs was observed at different parameters like temperature, concentration of silver nitrate, leaf extract concentration and time of reduction...
August 2017: IET Nanobiotechnology
Chun-Gang Yuan, Can Huo, Bing Gui, Wei-Ping Cao
The peel of Citrus maxima (C. maxima) is the primary byproducts during the process of fruit or juice in food industries, and it was always considered as biomass waste for further treatments. In this study, the authors reported a simple and eco-friendly method to synthesise gold nanoparticles (AuNPs) using C. maxima peel extract as reducing and capping agents. The synthesised AuNPs were characterised by UV-visible spectrum, X-ray diffraction (XRD), transmission electron microscope (TEM) and Fourier-transform infrared spectroscopy (FTIR)...
August 2017: IET Nanobiotechnology
Ali Es-Haghi, Mohammad Mashreghi, Mahere Rezazade Bazaz, Masoud Homayouni-Tabrizi, Majid Darroudi
The aim of this study is to introduce natural-based polymers, chitosan and starch, to design a remedial nanocomposite, comprising of cerium oxide nanoparticles and silver nanoparticles, to investigate their effects in accelerating wound healing and in wound microbial load. Cerium oxide nanoparticles synthesized in starch solution added to the colloidal dispersion of synthesized silver nanoparticles in chitosan to make a three-component nanomaterial. Mice were anaesthetized and two parallel full-thickness round wounds were excised under aseptic conditions with the help of sterile dermal biopsy punch...
August 2017: IET Nanobiotechnology
Jia-Ying Xin, Hong-Chen Fan, Sheng-Fu Ji, Yan Wang, Chun-Gu Xia
A green bioreductive approach with methanobactin was adopted to fabricate bimetallic Au-Pd/Al2O3 catalysts for solvent-free oxidation of glucose to gluconic acid with H2O2 at atmospheric pressure. The catalyst was characterised by diffuse reflectance UV-vis spectroscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, and X-ray diffraction techniques to understand synergistic interactions between Au and Pd. Effects of Au to Pd molar ratio on the catalytic activity of Au-Pd/Al2O3 were investigated...
August 2017: IET Nanobiotechnology
Geeta Arya, Nitin Kumar, Nidhi Gupta, Ajeet Kumar, Surendra Nimesh
Silver nanoparticles (AgNPs) have been extensively used as antibacterial agents, owing to their ease of preparation. In the present study, leaves extract of Canarium ovatum have been employed for the biosynthesis of silver nanoparticles (CO-AgNPs). CO-AgNPs were synthesised under very mild, eco-friendly manner where the plant extract acted both as reducing and capping agent. These AgNPs were synthesised by taking into account several parameters, that included, time of reaction, concentration of AgNO3, amount of extract and temperature of reaction...
August 2017: IET Nanobiotechnology
Md Iftekhar Hossain, Jarrod Edwards, James Tyler, John Anderson, Supriyo Bandyopadhyay
Silver is known to possess anti-microbial properties that are of chemical origin. It is believed that either Ag atoms bind to thiol groups in bacterial enzymes or Ag(+) ions enter bacterial cells and denature the DNA molecule to kill bacteria. Silver nanorods, however, may kill bacteria by another mechanism: it is possible that the sharp tips of the nanorods puncture bacterial cells and kill bacteria via impalement-a physical mechanism. To test if this can indeed happen, we have compared the anti-microbial properties of silver and CdS nanorods...
August 2017: IET Nanobiotechnology
Mehrdad Namdari, Babak Negahdari, Ali Eatemadi
The search for an optimal aortic valve implant with durability, calcification resistance, excellent haemodynamic parameters and ability to withstand mechanical loading is yet to be met. Thus, there has been struggled to fabricate bio-prosthetics heart valve using bioengineering. The consequential product must be resilient with suitable mechanical features, biocompatible and possess the capacity to grow. Defective heart valves replacement by surgery is now common, this improves the value and survival of life for a lot of patients...
August 2017: IET Nanobiotechnology
Farinaz Ghanbar, Amir Mirzaie, Fatemeh Ashrafi, Hassan Noorbazargan, Mojgan Dalirsaber Jalali, Soheil Salehi, Seyed Ataollah Sadat Shandiz
The focus of this study is on a rapid and cost-effective approach for the synthesis of silver nanoparticles (AgNPs) using Artemisia quttensis Podlech aerial parts extract and assessment of their antioxidant, antibacterial and anticancer activities. The prepared AgNPs were determined by ultraviolet-visible spectroscopy, X-ray diffraction, Fourier transform infra-red spectroscopy, transmission electron microscopy, scanning electron microscopy, energy-dispersive spectroscopy, and dynamic light scattering and zeta-potential analysis...
June 2017: IET Nanobiotechnology
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