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Journal of Digestive Diseases

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https://www.readbyqxmd.com/read/27930875/comparison-of-three-scoring-systems-in-predicting-clinical-outcomes-in-patients-with-acute-upper-gastrointestinal-bleeding-a-prospective-observational-study
#1
Min Zhong, Wan Jun Chen, Xiao Ye Lu, Jie Qian, Chang Qing Zhu
OBJECTIVE: To compare the performance of the Glasgow-Blatchford score (GBS), modified GBS (mGBS), and AIMS65 in predicting clinical outcomes in patients with acute upper gastrointestinal bleeding (AUGIB). METHODS: This study enrolled 320 consecutive patients with AUGIB. High-risk and low-risk patients were categorized according to the GBS, mGBS and AIMS65 scoring systems. The primary outcome was the occurrence of adverse events. Secondary outcomes were occurrences of rebleeding, in-hospital mortality, and need for clinical intervention...
December 8, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27860300/expert-consensus-on-perioperative-use-of-medications-during-endoscopic-submucosal-dissection-esd-for-gastric-lesions-2015-suzhou-china
#2
Yu Bai, Jian-Ting Cai, You Xiang Chen, Fei Gao, Xiao Zhong Guo, Xue Gang Guo, Ying Han, Jian Yu Hao, Shui Xiang He, Ming Ji, Bo Jiang, Hui Qing Jiang, Zhen Dong Jin, Yan Qing Li, Zhao Shen Li, Zhuan Liao, Feng Liu, Zhi Guo Liu, He Sheng Luo, Bin Lv, Nong Hua Lv, Xu Ren, Jian Qiu Sheng, Rui Hua Shi, De An Tian, Fang Yu Wang, Gui Qi Wang, Ai Ming Yang, Guo Xin Zhang, Zhen Yu Zhang, Fa Chao Zhi, Duo Wu Zou, Xiao Ping Zou
No abstract text is available yet for this article.
November 11, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27860427/the-role-of-adipoq-methylation-in-experimental-non-alcoholic-fatty-liver-disease
#3
Wen Ji Chen, Bing Cai, Hui Ting Chen, Chuang Yu Cao, Yan Lei Du, Yu Yuan Li, Yu Qiang Nie, Yong Jian Zhou
AIM: To investigate the role of adiponectin gene (ADIPOQ) DNA methylation and curcumin in the intervention of non-alcoholic fatty liver disease (NAFLD). METHODS: Twenty-four Sprague-Dawley (SD) rats were divided into three groups: normal, NAFLD and curcumin groups. The genetic and epigenetic features of each rat were tested. RT-PCR and western blot were used to quantify the ADIPOQ mRNA and protein level respectively. Bisulfite sequencing PCR (BSP) was used to detect the extent of methylation in rat livers...
November 9, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27768835/endoscopic-radiofrequency-ablation-may-be-preferable-in-the-management-of-malignant-biliary-obstruction-a-systematic-review-and-meta-analysis
#4
Xiao Zheng, Zhi Yuan Bo, Wei Wan, Ye Chen Wu, Tian Tian Wang, Jun Wu, Dao Jian Gao, Bing Hu
AIM: Endoscopic biliary radiofrequency ablation (RFA) has been increasingly used for unresectable malignant biliary obstruction (MBO). However, its efficacy and safety remain unclear. METHODS: A comprehensive search of Cochrane Library, PubMed and EMBASE was conducted to collect studies to evaluate endoscopic biliary RFA in the management of MBO. Meta-analysis was performed by extracting the data from included studies with regards to the technical effectiveness, overall survival, adverse events and mortality of endoscopic RFA...
October 21, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27743467/therapeutic-modulation-of-the-gut-microbiota-in-ibd-more-questions-to-be-answered
#5
Yu Qi Qiao, Chen Wen Cai, Zhi Hua Ran
Inflammatory bowel disease (IBD) patients exhibit impaired control of the microbiome in the gut. "Dysbiosis" is commonly observed. A Western diet is a risk factor for the development of IBD but may have different effects on the gut microbiota in IBD and non-IBD individuals. Exclusive enteral nutrition (EEN) can induce remission in pediatric Crohn's disease (CD) with a decrease in gut microbiome diversity after EEN treatment. Although there are some theoretical benefits, the actual treatment effects of prebiotics and probiotics in IBD patients can vary...
October 15, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27740709/consensus-of-experts-on-the-safe-operation-of-digestive-endoscopy-center-in-china
#6
Zhao Shen Li
No abstract text is available yet for this article.
October 14, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27739223/an-unusual-presentation-of-erdheim-chester-disease
#7
Sang Gyu Park, Dong Hoon Baek, Kyu Min Lee, Seo Young Oh, Do Youn Park, Sangjeong Ahn, Nari Shin, Geun Am Song
No abstract text is available yet for this article.
October 13, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27726286/reasons-and-risk-factors-for-irregular-interval-endoscopic-variceal-sclerotherapy-in-patients-with-esophageal-varices-bleeding
#8
Yi-Chao Shi, Xin Ma, Zhi-Yuan Guo, Xi Luo, Guo-Hui Sun, Hua Jiang, Wei-Feng Wang, Gang Sun, Yun-Sheng Yang
AIM: Endoscopic variceal sclerotherapy (EVS) is usually performed at weekly intervals in patients with esophageal variceal bleeding (EVB). However, some patients receive sclerotherapy at irregular intervals. The reasons and risk factors for irregular-interval treatment need to be clarified. METHODS: We retrospectively analyzed of hospital records from the Chinese PLA General Hospital, from December 2013 to June 2015. A total of 244 patients were admitted for EVS, which was scheduled to be repeated at regular weekly intervals...
October 11, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27684550/chronic-alcoholics-keep-dyspeptic-symptoms-pan-enteric-dysmotility-and-autonomic-neuropathy-before-and-after-abstinence
#9
Agostino Di Ciaula, Ignazio Grattagliano, Piero Portincasa
AIM: To perform a comprehensive study on gastrointestinal symptoms, motility and autonomic neuropathyin chronic alcoholics before and one year after abstinence. METHODS: Dyspeptic symptoms (questionnaires), fasting and postprandial gallbladder and gastric motility (ultrasonography), oro-cecal transit time (lactulose H2 -breath test), stool form score (indirect marker of colonic transit), and autonomic neuropathy (sweat spot test, R-R ratio) were assessed at baselinein 268subjects (136chronic alcoholics,132healthy controls)...
September 29, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27653444/standard-dose-versus-low-dose-of-azathioprine-in-the-treatment-of-crohn-s-disease-a-prospective-randomized-study
#10
Yu Zhang, Jingjing Xia, Peng Xiao, Yuan Zhao, Lingna Ye, Xiaolin Li, Ziwen Lin, Zhenjie Xu, Yibiao Huang, Mengyu Wang, Jiaming Qian, Pinjin Hu, Qian Cao
OBJECTIVE: Azathioprine (AZA) is widely used in Crohn's disease (CD) patients with a recommended dose, 2-2.5 mg/kg/d, for Westerners. Asian patients are suggested with a lower dose. However, many clinicians reported a poor efficacy with a reduced dose. Our prospective study aims to find a safe dose providing the best efficacy for Chinese CD patients. METHODS: Fifty active Chinese CD patients were enrolled in our test and randomly split into 2 groups, 25 each. All other treatments were the same except that group A took 1 mg/kg/d and group B took 2 mg/kg/d of AZA...
September 21, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27628945/micrornas-as-biomarkers-and-regulators-of-nonalcoholic-fatty-liver-disease
#11
Xiao Lin Liu, Hai Xia Cao, Jian Gao Fan
Nonalcoholic fatty liver disease (NAFLD) is a complicated disease affected by the interaction between environmental and genetic factors, and the precise pathogenesis of the disease is not fully understood. There is a need to better understand the pathogenesis of NAFLD and identify noninvasive diagnostic methods. Recent advances in systems biology and epigenetics have improved our understanding of the genotype-phenotype relationships present in NAFLD. MicroRNAs e important regulators of a wide range of biological processes, and they are protected from the RNAase in body fluids and are extremely stable, making them attractive candidate biomarkers for the early detection of disease and monitoring disease progression...
September 15, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27624697/effective-endoscopic-treatment-of-mallory-weiss-syndrome-using-glasgow-blatchford-score-and-forrest-classification
#12
Sunpyo Lee, Ji Yong Ahn, Hwoon-Yong Jung, Kee Wook Jung, Jeong Hoon Lee, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Jin-Ho Kim, Seon-Ok Kim
AIM: There is limited data on whether scoring systems can be used to predict clinical outcomes in patients with upper gastrointestinal bleeding due to Mallory-Weiss syndrome (MWS). We evaluated whether the Glasgow-Blatchford score (GBS) could be effective in predicting clinical outcomes of bleeding MWS. We also investigated the predictive ability of the Forrest classification for rebleeding and assessed the effective endoscopic modalities for bleeding control in MWS. METHODS: From January 2004 to December 2012, 168 patients were diagnosed with MWS in Asan Medical Center emergency department...
September 13, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27624611/intestinal-injury-in-the-rat-model-of-17%C3%AE-ethynylestradiol-induced-intrahepatic-cholestasis
#13
Mu-Jun Chang, Yan-Jiao Xu, Wen-Xi He, Cheng-Liang Zhang, Xi-Ping Li, Dong Liu
AIMS: Although the intimate relationship between liver and gut has been previously reported in physiological and pathological conditions, intestinal involvement in the process of intrahepatic cholestasis of pregnancy has been unclear. The aim of this study was to investigate the intestinal changes in 17α-ethynylestradiol-induced rat model. METHODS: Liver injury was assessed by hematoxylin and eosin staining and measurement of serum biochemical parameters. Intestinal transit was determined by a method using ink...
September 13, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27622897/alginate-antacid-gaviscon-double-action-chewable-tablets-reduce-esophageal-acid-exposure-in-chinese-patients-with-gastroesophageal-reflux-disease-and-heartburn-symptoms
#14
Yao Zong Yuan, Jing Yuan Fang, Duo Wu Zou, Nigel Levinson, Bartosz Jenner, Joanne Wilkinson
AIM: To assess efficacy ofDA alginate-antacidchewable tablets for reducing esophageal acid exposure in Chinese patients with gastroesophageal reflux disease (GERD) METHODS: Forty-fourpatients reporting moderately severe heartburn symptomsunderwent two pHmonitoring visits. Treatment sequence was randomized:patients receivedDAalginate-antacid or placebo at one visit and the alternate treatment seven days later. Aftera standardizedreflux-provoking meal,patients took four tablets of DAalginate-antacid or placebo...
September 13, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27598885/thrombophlebitis-of-cephalic-vein-in-the-left-forearm-related-to-infliximab-infusion
#15
Zhi Yin Huang, Ling Lin, Qin Tang, Yu Fang Wang
No abstract text is available yet for this article.
September 6, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27882730/corrigendum
#16
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27653317/author-index
#17
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27653316/others
#18
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27653315/abstracts-published-only
#19
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27653314/poster
#20
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Journal of Digestive Diseases
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