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Journal of Digestive Diseases

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https://www.readbyqxmd.com/read/28753222/acute-hemorrhagic-rectal-ulcer-ahru-syndrome-comparison-with-non-ahru-lower-gastrointestinal-bleeding
#1
Joo Hyuk Jung, Jong Wook Kim, Hyun Woo Lee, Min Yong Park, Woo Hyun Paik, Won Ki Bae, Nam-Hoon Kim, Kyung-Ah Kim, June Sung Lee
AIM: Acute hemorrhagic rectal ulcer (AHRU) syndrome can cause massive, life-threatening rectal bleeding. Sigmoidoscopic hemostasis with enema can often be performed to effectively control rectal bleeding. METHODS: The medical records of AHRU patients were retrospectively reviewed. The baseline clinical characteristics were compared with those of non-AHRU lower gastrointestinal bleeding patients to identify predictive factors for AHRU. RESULTS: Among the 118 patients who underwent emergent endoscopy due to acute massive hematochezia from 2013 to 2015, 25 (21...
July 28, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28749602/clinical-pattern-and-prevalence-of-upper-gastrointestinal-toxicity-in-ketamine-abusers
#2
Shirley Yuk Wah Liu, Stephen Ka Kei Ng, Yuk Him Tam, Samuel Chi Hang Yee, Franco Pui Tak Lai, Cindy Yuek Lam Hong, Philip Wai Yan Chiu, Enders Kwok Wai Ng, Chi Fai Ng
AIM: While evidence about ketamine-related urological and hepatobiliary injuries was emerging, evaluation about upper gastrointestinal toxicity from ketamine abuse was uncommon. This study aims to investigate the clinical pattern and prevalence of upper gastrointestinal symptoms in inhalational ketamine abusers. METHODS: This was a cross sectional study of 611 consecutive ketamine abusers who were seeking treatment for ketamine uropathy in a tertiary hospital setting between August 2008 and June 2016...
July 27, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28749599/heat-induced-inflammation-and-its-role-in-esophageal-cancer
#3
REVIEW
Mohaddese Maghsudlu, Ehsan Farashahi Yazd
Esophageal cancer as the sixth common cause of cancer death in the world consists of different histological types with various incidence patterns. Among them, esophageal adenocarcinoma and esophageal squamous cell carcinoma are the most prevalent types which also have different causality, cell of origin and risk factors. Since epidemiological studies have announced consumption of hot substances as one of the major risk factors for squamous cell carcinoma, evaluating the effect of this external stress on esophagus cells seems desirable...
July 27, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28749071/hepatic-subcapsular-hematoma-breaking-into-the-abdominal-cavity-after-extracorporeal-shock-wave-lithotripsy-for-pancreatic-stones
#4
Bi Ya Wei, Dan Wang, Ting Ting Du, Zhuan Liao, Zhao Shen Li, Liang Hao Hu
Pancreatic extracorporeal shock wave lithotripsy (P-ESWL) has been recommended for the management of large pancreatic stones. It is considered to be a noninvasive and low morbidity procedure. However, despite its minimal invasiveness, it does have complications.
July 27, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28727260/gastric-per-oral-endoscopic-myotomy-g-poem-for-pylorospasm-case-report-and-literature-review
#5
Wen Wen Zheng, Ming Ming Zhang, Yan Zhang, Zhen Li, Xiu Li Zuo, Xue Feng Lu, Yan Qing Li
Gastric per oral endoscopic myotomy is a novel endoscopic technique, using mucosal incision and submucosal tunneling, to access and surgically divide the pyloric ring. It has been reported as a technically feasible procedure and minimally invasive therapy for refractory gastroparesis. We performed this procedure in a 63-year-old male patient with postoperative pylorospasm, with clinical success. Pylorospasm is one of pathophysiologic mechanisms underlying gastroparesis. As a subgroup of gastroparesis, pylorospasm should be identified to be an appropriate indication for gastric per oral endoscopic myotomy...
July 20, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28715114/a-rare-case-of-obstructive-duodenal-phytobezoar-caused-by-two-lipomas
#6
Eunae Cho, Chung Hwan Jun, Eun Kyu Park, Chang Hwan Park, Hyun Soo Kim, Sung Kyu Choi, Jong Sun Rew
The word 'bezoar' comes from either the Persian word 'padzahr' or the Arabic word 'badzehr' both of which denote 'antidote.' This word meant a hard stone found in the stomach of the Syrian goat and believed to prevent poisoning(1) .
July 17, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28682012/collagenous-colitis-presenting-with-skip-lesions-mimicking-crohn-s-disease-and-complicated-by-intestinal-obstruction
#7
Chee K Hui, N Kit Hui
Microscopic colitis is a chronic inflammatory disease that traditionally affects the large intestine. It is characterized by frequent episodic non-bloody watery diarrhea. Occasionally, microscopic colitis may present with abdominal pain, fecal incontinence and weight loss.
July 6, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28677349/comparison-of-efficacy-and-safety-of-hyoscine-butylbromide-versus-anisodamine-for-acute-gastric-or-intestinal-spasm-like-pain-a-randomized-double-blind-and-multi-center-phase-iii-trial
#8
Chun Ping Zhu, Fei Jiang, Rong Quan Wang, Xiao Zhong Guo, Xiao Hua Hou, Hong Xu, Ya Zeng, Yi Qi Du, Zhao Shen Li
AIM: Acute gastric or intestinal spasm-like pain is a common symptom in digestive diseases. Hyoscine butylbromide (HBB), an anticholinergic agent, relieves the pain of stomach and bowel cramps by inhibiting smooth muscle contractility. The aim was to compare the efficacy and safety of parenteral HBB versus anisodamine, for acute gastric or intestinal spasm-like pain. METHODS: In this randomized, positive-controlled, double-blind, parallel-group, multi-center non-inferiority trial, 299 Chinese patients were randomly assigned to HBB or anisodamine in a 1:1 ratio...
July 5, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28671770/clinical-outcomes-of-patients-with-resectable-pancreatic-acinar-cell-carcinoma
#9
Seyoung Seo, Changhoon Yoo, Kyu-Pyo Kim, Baek-Yeol Ryoo, Heung-Moon Chang, Seung-Mo Hong, Jae Hoon Lee, Ki Byung Song, Dae Wook Hwang, Ki-Hun Kim, Shin Hwang, Song Cheol Kim
AIM: With rarity of disease, the post-resection clinical course of localized pancreatic acinar cell carcinoma (ACC) is largely unknown. Therefore, we analyzed the outcomes of patients with localized pancreatic ACCs who underwent surgical resection. METHODS: We retrospectively analyzed the outcomes of 20 patients with resectable pancreatic ACC who underwent surgery. RESULTS: Median age was 57 years and 16 were male. The ACCs were composed of 8 pure ACCs, 10 mixed acinar-neuroendocrine carcinomas, and 2 mixed acinar-ductal adenocarcinomas...
July 3, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28671764/the-evaluation-of-the-non-invasive-msct-based-indices-for-the-diagnosis-and-prognosis-prediction-of-liver-cirrhosis
#10
Ling-Mei Feng, Shu-Juan Lei, Xin Zeng, Pei-Qin Wang, Ru-Tan Chen, Jian Wang, Xia Sheng, Pei-Mei Shi, Zong-Li Yuan, Wei-Fen Xie
PURPOSE: It is necessary to develop feasible and reliable non-invasive methods to determine liver function and predict complications in patients with liver cirrhosis. The aim of this study was to determine the value of CT-based easily available parameters in evaluating the severity of cirrhosis and predicting complications in Chinese cirrhotic patients. METHODS: CT-based morphological indices were determined in 167 cirrhotic patients and 244 healthy volunteers. The correlation of morphological indices with the Child-Pugh score/grade and complication of cirrhosis was analysed by Spearman correlation analysis...
July 3, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28644907/optimal-duration-of-fasting-period-after-endoscopic-submucosal-dissection-for-gastric-epithelial-neoplasia-a-prospective-evaluation-of-short-versus-long-fasting-period
#11
Kwang Hoon Oh, Sang Jin Lee, Jong Kyu Park
OBJECTIVE: There are currently no standardized guidelines for adequate determination of fasting period following gastric ESD. The aim of this study was to determine the appropriate length of fasting period. METHODS: Enrolled patients were randomized into a short fasting group and a long fasting group. In the short fasting group, patients had been fasting until the next day after ESD. In the long fasting group, patients had been fasting until two days after ESD. A second-look endoscopy was performed immediately prior to starting diet...
June 23, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28644575/comparison-of-10-days-levofloxacin-bismuth-based-quadruple-therapy-and-levofloxacin-based-triple-therapy-for-helicobacter-pylori-therapy
#12
Tzung-Shiun Wu, Ping-I Hsu, Chao-Hung Kuo, Huang-Ming Hu, I-Chen Wu, Sophie S W Wang, Yen-Hsu Chen, Deng-Chyang Wu, Wei-Wen Su, Fu-Chen Kuo
BACKGROUND: This was a prospective study, the aid was to prove if levofloxacin plus Bismuth-based quadruple therapy was more effective than levofloxacin-based triple therapy after failure of first-line therapies. METHODS: We collected total of 67 patients, who was infected by H.pylori. Patients were enrolled and were randomly assigned to two groups; one was levofloxacin plus Bismuth-based quadruple therapy (RBAL group) (Rabeprazole 20 mg b.i.d., bismuth subcitrate 120 mg q...
June 23, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28644566/clinical-characteristics-and-outcome-of-liver-transplantation-for-alagille-syndrome-in-children
#13
Tao Zhou, Jianjun Zhang, Yi Luo, Yuan Liu, Sy Zhuang, Feng Xue, Longzhi Han, Qiang Xia
AIM: The aim of this study was to analyze clinical characteristics and outcome of liver transplantation for Alagille syndrome in children. METHOD: By retrospectively reviewing the medical records of 9 Alagille syndrome patients(AGS) with liver transplantation(LT) in Renji Hospital between 2006 and 2015,After operative,the height and weight Z score were compared with preoperative. RESULT: There were 9 patients included in the study; cholestasis and peculiar faces were seen in all of the patients (100%), heart defect in 8 patients (88...
June 23, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28644565/long-term-risk-of-infection-in-patients-with-crohn-s-disease-on-anti-tnf-treatment-a-prospective-single-center-cohort-study-in-china
#14
Yue Li, Hui Jun Shu, Hong Lu, Hong Yang, Ji Li, Bei Tan, Jiaming Qian
BACKGROUND: Anti-TNF agents have demonstrated to greatly improve management strategies for inflammatory bowel disease (IBD). Clinical trials and registry studies in Western countries have shown that infections and malignancy are the most concerned complications of anti-TNF treatment. However, data derived from clinical practice in China are limited. The aim of this study is to explore the long-term infection risk of infliximab (IFX) in treating patients with Crohn's disease (CD) from a tertiary IBD center in China...
June 23, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28608655/endoscopic-evaluation-of-iron-deficiency-without-anemia-does-it-have-the-same-benefit-as-in-patients-with-anemia
#15
Ana García García de Paredes, Carlos Teruel Sánchez-Vegazo, Nerea Hernanz Ruiz, Carlos Ferre Aracil, Enrique Rodríguez de Santiago, Lara Aguilera Castro, María Sierra Morales, Agustín Albillos
BACKGROUND AND AIM: The need for endoscopic investigation in patients with iron deficiency without anemia (ID) is not established. METHODS: Data from patients with ID (serum ferritin ≤20 ng/mL, normal hemoglobin) studied with upper and lower endoscopy were retrospectively analyzed. Patients evaluated for iron deficiency anemia (IDA) served as controls, matched by sex and age in a proportion 2:1. Presence, type, location and age distribution of endoscopic findings were compared...
June 13, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28608600/the-hypoxia-il1a-axis-promotes-gastric-cancer-progression-and-drug-resistance
#16
Yi Xuan, Yanong Wang
AIM: Tumor microenvironment constitutes a unique niche that promotes cancer metastasis and resistance. Two remarkable characteristics of this microenvironment are hypoxia and inflammation. Interleukin-1 alpha (IL1A), an important inflammatory factor, is frequently upregulated in a variety of cancers. Herein, we set force to characterize IL1A expression in gastric cancer and explore the relationship between IL1A and hypoxia. METHODS: Reverse-transcriptase PCR (RT-PCR) was performed to characterize IL1A expression in different gastric cancer cell lines under normonia or hypoxia...
June 13, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28608576/evaluation-of-three-techniques-for-detection-of-il28b-snp-a-prognostic-tool-for-hcv-treatment-outcome
#17
Bushra Khubaib, Muhammad Idrees, Zareen Fatima, Madiha Akram, Samia Afzal, Iram Amin, Muhammad Shahid, Muhammad Wasim
OBJECTIVE: The study was accompanied to evaluate the specificity, cost and turn-around time of three different types of techniques that can be used for analysis of single nucleotide polymorphism of rs129796860. METHODS: One hundred and one samples of patients infected with chronic Hepatitis C were genotyped with the three types of genotyping methods: direct sequencing, SNaPshot PCR and PCR-Restriction fragment Length polymorphism. RESULTS: Three distinct profiles for IL28B rs12979860 alleles (CC, CT and TT) were obtained with direct sequencing; SNaPshot PCR and PCR-RFLP and the results were consistent among the three methods...
June 13, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28585279/serum-bile-acid-level-and-fatty-acid-composition-in-chinese-children-with-non-alcoholic-fatty-liver-disease
#18
Li Ping Lu, Yan Ping Wan, Peng Cheng Xun, Ke Jun Zhou, Cheng Chen, Si Yang Cheng, Min Zhong Zhang, Chun Hua Wu, Wei Wei Lin, Ying Jiang, Hai Xia Feng, Jia Lu Wang, Ka He, Wei Cai
OBJECTIVE: To determine serum bile acid (BA) and fatty acid (FA) profiles in Chinese children with non-alcoholic fatty liver disease (NAFLD) METHODS: Seventy-six children aged 4-17 years were categorized into three groups: none NAFLD (control), mild, and moderate/severe NAFLD groups respectively based on liver ultrasonography. Serum BAs and FAs were quantified by mass spectrometry and gas chromatography separately. General linear models were performed to assess the differences across groups...
June 6, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28548239/impact-of-barium-enema-on-acute-diverticulitis-recurrence-a-retrospective-cohort-study-of-349-patients
#19
Francisco J Medina-Fernández, Lidia Rodríguez-Ortiz, Dimas J Garcilazo-Arismendi, Elena Navarro-Rodríguez, Eva M Torres-Tordera, César A Díaz-López, Javier Briceño
AIM: Acute diverticulitis is becoming a health concern in western countries as its incidence is increasing. Currently, one of the accepted theories on possible causes of diverticular perforation is the impactation of faecal residuals into some diverticula. Our aim was to evaluate whether barium impactation might have a negative effect by promoting diverticular inflammation/rupture and thereby acute diverticulitis recurrence. METHODS: A retrospective cohort study (January 2005/December 2015) was conducted at the Reina Sofia University Hospital of Cordoba (Spain)...
May 26, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28547873/can-clinical-factors-predict-the-need-for-intervention-after-positive-intraoperative-cholangiogram
#20
Mohammed Kaif, Deepak Agrawal, Jayaprakash Sreenarasimhaiah
BACKGROUND/AIMS: Intraoperative cholangiogram (IOC) is commonly used to detect retained bile duct stones. This often leads to another invasive procedure such as endoscopic retrograde cholangiopancreatography (ERCP). However, due to the variation in methods and results of IOC, it is unclear if clinical factors will aid in identifying true choledocholithiasis. METHODS: All cholecystectomies in a 3 year period were examined retrospectively for positive IOC. Sonographic bile duct dilation and transaminase levels at admission including trends during the course of hospitalization and prior to ERCP were evaluated...
May 26, 2017: Journal of Digestive Diseases
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