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Gastrointestinal Cancer Research: GCR

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https://www.readbyqxmd.com/read/27053977/clinical-applications-of-liquid-biopsies-in-gastrointestinal-oncology
#1
Anastasia Katsiampoura, Scott Kopetz
Accumulating knowledge in colorectal cancer (CRC) biology has led to an understanding of the role of genetic and epigenetic alterations in tumorigenesis and progression of the disease. Numerous studies have focused on the identification of novel biomarkers in circulating free (cf)DNA that have the potential of guiding clinical practice. These markers are specifically attractive for the characterization of molecular profiles in patients with limited tissue access, the monitoring of therapeutic responses and the development of recurrent disease, the monitoring of the tumor evolution with therapy, and the response to therapy...
September 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/27053976/cme-post-test
#2
(no author information available yet)
No abstract text is available yet for this article.
September 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/27053975/novel-therapies-in-development-for-metastatic-colorectal-cancer
#3
Michael S Lee, Scott Kopetz
Colorectal cancer (CRC) is the second most common cause of cancer mortality in the United States. Despite advances in therapy, metastatic CRC remains lethal, and further improvements in therapy are needed. Growing understanding of cancer biology, particularly in growth factor signaling, angiogenesis, and cancer immunology, has translated into many novel therapies under investigation. Patients are increasingly selected for clinical trials rationally on the basis of integral biomarkers. This review discusses several promising agents in development for metastatic CRC...
September 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/25276270/multiorgan-streptococcus-milleri-abscesses-during-folfirinox-chemotherapy-in-a-patient-with-metastatic-pancreatic-cancer
#4
Evelyn Brosnan, Kabir Mody, Richard A Zuckerman, Kathryn L Ruoff, J Marc Pipas
No abstract text is available yet for this article.
May 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/25276269/benign-schwannoma-masquerading-as-a-malignant-metastatic-lesion-in-a-patient-with-renal-cell-carcinoma
#5
Santhosh Sadashiv, Georgios Deftereos, Eli Pakravan, Jan F Silverman, Shifeng Mao
No abstract text is available yet for this article.
May 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/25276268/a-case-of-primary-colonic-small-cell-carcinoma-arising-in-a-patient-with-long-standing-ulcerative-colitis
#6
Renée M Marchioni Beery, Thomas J Devers, Jessica M Clement
No abstract text is available yet for this article.
May 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/25276267/metastatic-breast-cancer-masquerading-as-primary-gastric-cancer-case-report-and-review-of-the-literature
#7
Alexander C Black, Danielle Lu, Susan Murakami
No abstract text is available yet for this article.
May 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/25276266/hepatocellular-carcinoma-with-intra-atrial-extension-responding-to-transarterial-chemoembolization-via-the-right-hepatic-and-right-inferior-phrenic-arteries
#8
Maen W H Kamal, Maham Farshidpour, Andrew W Long, Saleem Farooqui, Steven C Cunningham
No abstract text is available yet for this article.
May 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/25276265/pseudomyxoma-peritonei-metastatic-to-the-bone-case-report-and-review-of-systemic-management
#9
Renata D'Alpino Peixoto, Sheridan Wilson, David F Schaeffer, Howard J Lim
No abstract text is available yet for this article.
May 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/25276264/from-the-liver-to-the-foot-a-case-of-systemic-embolism-and-acrometastasis-in-hepatocellular-carcinoma
#10
Ghaith Abu-Zeinah, Dwight Owen, Carlos Prieto-Granada, Natasha Rekhtman, David Klimstra, Dipti Gupta, James Harding, Ghassan K Abou-Alfa
No abstract text is available yet for this article.
May 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/25276263/challenges-in-combining-antiangiogenic-therapy-with-transarterial-chemoembolization-for-hepatocellular-carcinoma
#11
Ali A Haydar, Deborah Mukherji, Walid Faraj, Mohammad Khalifeh, Bedros Taslakian, Zeinab Abou Yehia, Sally Temraz, Karen T Brown, Ghassan K Abou-Alfa, Ali Shamseddine
BACKGROUND: The combination of systemic antiangiogenic therapy and transarterial chemoembolization (TACE) for the treatment of unresectable hepatocellular carcinoma (HCC) is the subject of several ongoing clinical trials. We present a series of patients treated with sorafenib and TACE at our institution, highlighting the technical challenges of combining these two modalities of treatment. METHODS: We retrospectively identified patients with HCC treated with TACE and sorafenib at our institution...
May 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/25276262/maintenance-therapy-with-capecitabine-in-patients-with-resected-pancreatic-adenocarcinoma-after-adjuvant-therapy-a-retrospective-cohort-study
#12
Benjamin A Weinberg, Hongkun Wang, Xuezhong Yang, Christina S Wu, Michael J Pishvaian, Aiwu R He, John L Marshall, Jimmy J Hwang
BACKGROUND: The 5-year survival of pancreatic adenocarcinoma with surgery and adjuvant chemotherapy is below 25%. The original Gastrointestinal Tumor Study Group (GITSG) adjuvant study demonstrated a survival benefit attributed to weekly intravenous boluses of 5-fluorouracil (5-FU) for 2 years in addition to chemoradiation compared to surgery alone. In theory, the prolonged exposure to therapy could maintain pressure on dormant cancer cells that remain in G0 arrest and kill them as they infrequently enter the G1/S phase...
May 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/25276261/benefit-of-adjuvant-chemoradiotherapy-for-gastric-adenocarcinoma-a-seer-population-analysis
#13
Steven Seyedin, Pin-Chieh Wang, Quan Zhang, Percy Lee
BACKGROUND: Despite results of the Intergroup 0116 (INT-0116) study showing an overall survival benefit of adjuvant chemoradiotherapy in gastric adenocarcinoma, its use in the United States remains controversial. The Surveillance Epidemiology of End Results (SEER) database was used to compare cause-specific survival outcomes in resected gastric adenocarcinoma with various adjuvant therapies and patterns of care. METHODS: Individual data from 1988 to 2008 were selected for patients with resected, nonmetastatic gastric adenocarcinoma...
May 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/25276260/quantitative-perfusion-and-diffusion-weighted-magnetic-resonance-imaging-of-gastrointestinal-cancers-treated-with-multikinase-inhibitors-a-pilot-study
#14
Hyunki Kim, Kimberly S Keene, David B Sarver, S Kyle Lee, T Mark Beasley, Desiree E Morgan, James A Posey
BACKGROUND: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted imaging (DWI) are often used to detect the early response of solid tumors to an effective therapy. The early changes in intratumoral physiological parameters measured by DCE-MRI/DWI have been evaluated as surrogate biomarkers allowing a tailored treatment for the individual patient. METHODS: Patients with newly diagnosed, biopsy-proven, treatment-naïve gastrointestinal stromal tumor (GIST) or hepatocellular carcinoma (HCC) were enrolled prospectively after institutional review board (IRB)-approved informed consent (5 patients per tumor type)...
May 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/24799978/upcoming-articles
#15
(no author information available yet)
No abstract text is available yet for this article.
March 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/24799977/information-for-contributors
#16
(no author information available yet)
No abstract text is available yet for this article.
March 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/24799976/definitive-chemoradiation-in-oligometastatic-squamous-cell-carcinoma-of-the-anal-canal
#17
Jane E Rogers, Christopher H Crane, Prajnan Das, Marc Delclos, M Spencer Gould, Aki Ohinata, Daniel Malatek, Cathy Eng
No abstract text is available yet for this article.
March 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/24799975/littoral-cell-angioma-gastrointestinal-associations
#18
John J Sarandria, Maria Escano, Farin Kamangar, Saleem O Farooqui, Elizabeth Montgomery, Steven C Cunningham
No abstract text is available yet for this article.
March 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/24799974/metastatic-non-small-cell-lung-cancer-to-the-liver-and-pancreas
#19
Laurie Matt, Rajesh Sehgal
No abstract text is available yet for this article.
March 2014: Gastrointestinal Cancer Research: GCR
https://www.readbyqxmd.com/read/24799973/acute-gout-episodes-during-treatment-with-capecitabine-a-case-report
#20
Renata D'Alpino Peixoto, Rachel Cossetti, Howard Lim, Winson Y Cheung, Hagen Kennecke
No abstract text is available yet for this article.
March 2014: Gastrointestinal Cancer Research: GCR
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