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Journal of Nutrigenetics and Nutrigenomics

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https://www.readbyqxmd.com/read/28877523/11th-congress-of-the-international-society-of-nutrigenetics-nutrigenomics-isnn-abstracts
#1
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No abstract text is available yet for this article.
September 7, 2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/29518768/isnn-society-news
#2
(no author information available yet)
No abstract text is available yet for this article.
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/29462810/consumption-of-amaranth-induces-the-accumulation-of-the-antioxidant-protein-paraoxonase-arylesterase-1-and-modulates-dipeptidyl-peptidase-iv-activity-in-plasma-of-streptozotocin-induced-hyperglycemic-rats
#3
Aída J Velarde-Salcedo, Evelyn Regalado-Rentería, Rodrigo Velarde-Salcedo, Bertha I Juárez-Flores, Alberto Barrera-Pacheco, Elvira González de Mejía, Ana P Barba de la Rosa
BACKGROUND/AIM: Amaranth is a source of several bioactive compounds, among which peptides with inhibitory activity upon dipeptidyl peptidase IV (DPP-IV) have been reported. However, there is no information about the action of amaranth DPP-IV-inhibitory peptides using in vivo models. The aim of this work was to evaluate the effect of amaranth consumption on plasma and kidney DPP-IV activity as well the changes in plasma proteome profile of streptozotocin (STZ)-induced hyperglycemic rats...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/29402779/the-combined-effects-of-genetic-variation-in-the-cndp1-and-cndp2-genes-and-dietary-carbohydrate-and-carotene-intake-on-obesity-risk
#4
Kimiko Yamakawa-Kobayashi, Eri Otagi, Yuya Ohhara, Toshinao Goda, Nobuhiko Kasezawa, Yasunari Kayashima
BACKGROUND/AIMS: It is possible that carnosinase (CNDP1) and cellular nonspecific dipeptidase (CNDP2) have important roles in protecting cells and tissues against the damage of oxidative stress. Oxidative stress and subsequent inflammation are key factors in the development of common chronic metabolic diseases, such as obesity. We aimed to investigate the combined effects of genetic variations in CNDP1 and CNDP2 and dietary carbohydrate and carotene intake on obesity risk. METHODS: A total of 1,059 Japanese men were randomly selected from participants who visited a medical center for routine medical checkups...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/29402778/interaction-of-vitamin-e-intake-and-pro12ala-polymorphism-of-pparg-with-adiponectin-levels
#5
Wendy Campos-Perez, Nathaly Torres-Castillo, Mariana Perez-Robles, Jose Francisco Muñoz-Valle, Barbara Vizmanos-Lamotte, Erika Martinez-Lopez
BACKGROUND/AIM: One of the beneficial effects associated with vitamin E intake is the enhancement of peroxisome proliferator-activated receptor gamma (PPARγ) activity and the consequent upregulation of adiponectin expression. The aim of this study was to analyze the adiponectin levels in subjects with the Pro12Ala polymorphism of PPARG according to vitamin E intake. METHODS: A total of 283 subjects were enrolled. Total vitamin E intake was estimated based on a validated 3-day food consumption record and analyzed using Nutritionist ProTM software...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/29339649/cardiovascular-risk-factors-and-insulin-resistance-after-two-hypocaloric-diets-with-different-fat-distribution-in-obese-subjects-effect-of-the-rs10767664-gene-variant-in-brain-derived-neurotrophic-factor
#6
Daniel Antonio de Luis, Enrique Romero, Olatz Izaola, David Primo, Rocío Aller
BACKGROUND: The role of brain-derived neurotrophic factor (BDNF) variants on change in body weight and cardiovascular risk factors after weight loss remains unclear in obese patients. OBJECTIVE: Our aim was to analyze the effects of the rs10767664 BDNF gene polymorphism on body weight, cardiovascular risk factors, and serum adipokine levels after a high monounsaturated fatty acids (MUFAs) hypocaloric diet (diet M) versus a high polyunsaturated fatty acids (PUFAs) hypocaloric diet (diet P)...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/29339647/proceedings-of-the-11th-congress-of-the-international-society-of-nutrigenetics-and-nutrigenomics-isnn-2017
#7
William T Barrington, Anna C Salvador, Jaana A Hartiala, Raffaele De Caterina, Martin Kohlmeier, J Alfredo Martinez, Carin B Kreutzer, David Heber, Aldons J Lusis, Zhaoping Li, Hooman Allayee
The International Society of Nutrigenetics and Nutrigenomics (ISNN) held its 11th annual Congress in Los Angeles, California, between September 16 and 19, 2017. In addition to 2 keynote lectures, 4 plenary sessions included presentations by internationally renowned speakers on cutting-edge areas of research and new discoveries in genetics/genomics, the microbiome, and nutrition. Scientific topics included multi-omics approaches; diet and the microbiome; cancer, longevity, and metabolism; moving the field forward; and translational/educational aspects and the future of medicine...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/29151102/the-effect-of-genistein-supplementation-on-vitamin-d-levels-and-bone-turnover-markers-during-the-summer-in-healthy-postmenopausal-women-role-of-genotypes-of-isoflavone-metabolism
#8
María Pérez-Alonso, Laisa-Socorro Briongos, Marta Ruiz-Mambrilla, Eladio A Velasco, Lidia Linares, Luis Cuellar, José-Manuel Olmos, Daniel De Luis, Antonio Dueñas-Laita, José-Luis Pérez-Castrillón
AIMS: The objective of this study was to determine whether vitamin D and genistein supplementation had an additive beneficial effect on levels of vitamin D and bone markers and whether this effect was mediated by genes regulating isoflavone metabolism. MATERIALS AND METHODS: We carried out a prospective study in postmenopausal women randomized to calcium and vitamin D supplementation or calcium, vitamin D, and genistein supplementation. Vitamin D, parathyroid hormone (PTH), cross-linked C-telopeptide (CTX), and procollagen 1 N-terminal (P1NP) were determined by electrochemiluminescence...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/29040973/sulforaphane-and-epigallocatechin-gallate-restore-estrogen-receptor-expression-by-modulating-epigenetic-events-in-the-breast-cancer-cell-line-mda-mb-231-a-systematic-review-and-meta-analysis
#9
Vincenza Gianfredi, Samuele Vannini, Massimo Moretti, Milena Villarini, Nicola Luigi Bragazzi, Alberto Izzotti, Daniele Nucci
BACKGROUND/AIMS: Epigenetics refers to modifications in gene activity and expression without alteration at the DNA sequence. Environment and diet could influence gene expression. Diet modifications may be meaningful in preventing and treating chronic diseases, cancer included. Dietary bioactive compounds, such as polyphenols (e.g., curcumin, resveratrol, or epigallocatechin gallate [EGCG]) or isothiocyanate (e.g., sulforaphane [SFN]), can regulate histone acetylation. The aim of this systematic review and meta-analysis was to evaluate the effect of SFN and EGCG on breast cancer (BC) cells cultured in vitro...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28858874/variants-in-chemosensory-genes-are-associated-with-picky-eating-behavior-in-preschool-age-children
#10
Natasha Chong Cole, Anthony A Wang, Sharon M Donovan, Soo-Yeun Lee, Margarita Teran-Garcia
BACKGROUND/AIMS: Picky eating is prevalent among preschoolers and is associated with risk of both underweight and overweight. Although differences in taste perception may be due to genetic variation, it is unclear whether these variations are related to picky eating behavior. The aim of this study was to investigate the association of 6 single nucleotide polymorphisms (SNPs) in 5 candidate genes related to chemosensory perception with picky eating behavior and adiposity in a cohort of preschool-aged children...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28858873/circulating-triglycerides-and-the-association-of-triglycerides-with-dietary-intake-are-altered-by-alpha-2-heremans-schmid-glycoprotein-polymorphisms
#11
Katie N Robinson, Itzel Vazquez-Vidal, Courtney Marques, Flavia Cristina Drumond Andrade, Celia Aradillas-Garcia, Margarita Teran-Garcia
BACKGROUND: Circulating fetuin-A (FetA) inhibits insulin receptor signaling and activates the toll-like receptor 4 proinflammatory cascade; thus, it may contribute to metabolic syndrome. Polymorphisms in alpha-2-Heremans-Schmid glycoprotein (AHSG), the gene which codes FetA, may influence metabolic syndrome progression in higher-risk ethnic groups. We aimed to identify whether individual variation in AHSG influences biomarkers of metabolic disease and obesity in young Mexican adults. METHODS: The participants were Mexican college applicants (18-25 years, n = 641)...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28787737/polymorphism-rs16147-of-the-neuropeptide-y-gene-modifies-the-response-of-cardiovascular-risk-biomarkers-and-adipokines-to-two-hypocaloric-diets
#12
RANDOMIZED CONTROLLED TRIAL
Daniel Antonio de Luis, Olatz Izaola, David Primo, Rocio Aller
AIMS: Our aim was to evaluate the relationship of weight loss and changes in adipokine levels after two hypocaloric diets in obese subjects with polymorphism rs16147 of the neuropeptide Y gene. SUBJECTS AND METHODS: A population of 283 obese patients was analyzed. At the basal visit, patients were randomly allocated to one of two diets for a period of 3 months (diet I, low in carbohydrates; diet II, low in fat). RESULTS: With diet I and in both genotype groups (major versus minor allele), body mass index (BMI), weight, fat mass, waist circumference, and leptin decreased...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28689206/guide-for-current-nutrigenetic-nutrigenomic-and-nutriepigenetic-approaches-for-precision-nutrition-involving-the-prevention-and-management-of-chronic-diseases-associated-with-obesity
#13
Omar Ramos-Lopez, Fermín I Milagro, Hooman Allayee, Agata Chmurzynska, Myung Sook Choi, Rui Curi, Raffaele De Caterina, Lynnette R Ferguson, Leticia Goni, Jing X Kang, Martin Kohlmeier, Amelia Marti, Luis A Moreno, Louis Pérusse, Chandan Prasad, Lu Qi, Ram Reifen, Jose I Riezu-Boj, Rodrigo San-Cristobal, Jose Luis Santos, J Alfredo Martínez
Chronic diseases, including obesity, are major causes of morbidity and mortality in most countries. The adverse impacts of obesity and associated comorbidities on health remain a major concern due to the lack of effective interventions for prevention and management. Precision nutrition is an emerging therapeutic approach that takes into account an individual's genetic and epigenetic information, as well as age, gender, or particular physiopathological status. Advances in genomic sciences are contributing to a better understanding of the role of genetic variants and epigenetic signatures as well as gene expression patterns in the development of diverse chronic conditions, and how they may modify therapeutic responses...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28578327/genetic-predictors-of-%C3%A2-5-weight-loss-by-multidisciplinary-advice-to-severely-obese-subjects
#14
Erik E J G Aller, Edwin C M Mariman, Freek G Bouwman, Marleen A van Baak
BACKGROUND: Weight loss success is determined by genetic factors, which may differ according to treatment strategy. METHODS: From a multidisciplinary obesity treatment program involving dietary advice, psychological counseling, and increased physical activity, 587 subjects (68% female; 46.1 ± 12.4 years; BMI 39.9 ± 6.3) were recruited. At baseline, a blood sample was drawn for DNA isolation. Genotypes were determined for 30 polymorphisms in 25 candidate genes...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28399529/in-utero-exposure-to-germinated-brown-rice-and-its-gaba-extract-attenuates-high-fat-diet-induced-insulin-resistance-in-rat-offspring
#15
Hadiza Altine Adamu, Mustapha Umar Imam, Ooi Der-Jiun, Maznah Ismail
BACKGROUND: Numerous studies have reported on the influence of diet on insulin resistance. Our study provides insight into the effect of germinated brown rice (GBR) and γ-aminobutyric acid (GABA) on early environment-driven programming and susceptibility to insulin resistance in rat offspring. METHODS: Male rat offspring from female Sprague-Dawley rats fed with a high-fat diet (HFD) alone, HFD + GBR, or HFD + GABA extract throughout pregnancy and lactation were weaned 4 weeks after delivery and followed up for 8 weeks...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28351026/common-variants-of-vitamin-d-receptor-gene-polymorphisms-and-susceptibility-to-coronary-artery-disease-a-systematic-review-and-meta-analysis
#16
REVIEW
Shahab Alizadeh, Kurosh Djafarian, Hamzeh Alizadeh, Reza Mohseni, Sakineh Shab-Bidar
BACKGROUND AND AIMS: ApaI, FokI, TaqI, and BsmI polymorphisms in the vitamin D receptor (VDR) gene have been reported to be associated with the risk of coronary artery disease (CAD), although the results of previous studies have been inconsistent. The aim of this study was to explore whether these polymorphisms play a role in the genetic susceptibility to CAD. METHODS: A comprehensive search of Medline and Embase databases was conducted for studies evaluating the association between the VDR polymorphisms and CAD risk...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28315876/angiotensin-converting-enzyme-ins-del-polymorphism-and-body-composition-the-intermediary-role-of-hydration-status
#17
Laura Bordoni, Valerio Napolioni, Francesca Marchegiani, Emilio Amadio, Rosita Gabbianelli
BACKGROUND: The well-known insertion/deletion polymorphism (rs4646994) of the angiotensin-converting enzyme (ACE) gene has been previously associated with obesity, blood flow, muscular strength, and ACE enzyme activity. Despite the relevant role of ACE in homeostasis, few data are currently available on the relationship between rs4646994 and hydration status. Thus, we tested the association between the ACE Ins/Del polymorphism, body composition, and hydration status in a young Italian population...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28245483/the-effect-of-apom-polymorphism-associated-with-hdl-metabolism-on-obese-korean-adults
#18
Myoungsook Lee, Jung-Im Kim, Seojin Choi, Yangsoo Jang, Sungbin Richard Sorn
BACKGROUND: Apolipoprotein M (apoM) is a recently identified apolipoprotein associated with high-density lipoprotein (HDL) in coronary artery disease (CAD), but the association between apoM polymorphism and obesity has not been reported. AIM: To investigate the association between apoM polymorphism and obesity prevalence in 584 Korean adults. METHODS: A total of 584 individuals aged between 30 and 80 years were recruited from Yonsei Medical Center in Seoul, Korea, and divided into obese (OB; body mass index, BMI ≥25) and nonobese (non-OB; BMI <25) groups...
2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28237985/genetic-variation-in-cd36-is-associated-with-decreased-fat-and-sugar-intake-in-obese-children-and-adolescents
#19
Marina B Pioltine, Maria Edna de Melo, Aritânia Santos, Alisson D Machado, Ariana E Fernandes, Clarissa T Fujiwara, Cintia Cercato, Marcio C Mancini
BACKGROUND/AIMS: Taste is recognized as an important predictor of food choices. Thus, polymorphisms in genes encoding taste receptors may explain the variability in food preference and intake. Here, we aimed to determine whether genetic variation in the CD36 gene affects food intake and risk of obesity. METHODS: A cross-sectional study was conducted with obese Brazilian children and adolescents (n = 466; BMI-for-age z-score [zBMI] 3.29 ± 0.61) and normal-weight children (n = 114; zBMI -0...
2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28214879/thiamine-deprivation-produces-a-liver-atp-deficit-and-metabolic-and-genomic-effects-in-mice-findings-are-parallel-to-those-of-biotin-deficiency-and-have-implications-for-energy-disorders
#20
Alain de J Hernandez-Vazquez, Josue Andres Garcia-Sanchez, Elizabeth Moreno-Arriola, Ana Salvador-Adriano, Daniel Ortega-Cuellar, Antonio Velazquez-Arellano
Thiamine is one of several essential cofactors for ATP generation. Its deficiency, like in beriberi and in the Wernicke-Korsakoff syndrome, has been studied for many decades. However, its mechanism of action is still not completely understood at the cellular and molecular levels. Since it acts as a coenzyme for dehydrogenases of pyruvate, branched-chain keto acids, and ketoglutarate, its nutritional privation is partly a phenocopy of inborn errors of metabolism, among them maple syrup urine disease. In the present paper, we report metabolic and genomic findings in mice deprived of thiamine...
2016: Journal of Nutrigenetics and Nutrigenomics
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