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Journal of Nutrigenetics and Nutrigenomics

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https://www.readbyqxmd.com/read/28002828/piper-betle-induced-cytoprotective-genes-and-proteins-via-the-nrf2-are-pathway-in-aging-mice
#1
Nor Syahida Aliahmat, Nur Fathiah Abdul Sani, Wan Nuraini Wan Hasan, Suzana Makpol, Wan Zurinah Wan Ngah, Yasmin Anum Mohd Yusof
BACKGROUND/AIMS: The objective of this study was to elucidate the underlying antioxidant mechanism of aqueous extract of Piper betle (PB) in aging rats. The nuclear factor erythroid 2-related factor 2 (Nrf2)/ARE pathway involving phase II detoxifying and antioxidant enzymes plays an important role in the antioxidant system by reducing electrophiles and reactive oxygen species through induction of phase II enzymes and proteins. METHODS: Genes and proteins of phase II detoxifying antioxidant enzymes were analyzed by QuantiGenePlex 2...
December 22, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28002826/the-capn2-capn8-locus-on-chromosome-1q-is-associated-with-variation-in-serum-alpha-carotene-concentrations
#2
Christopher R D'Adamo, Valerie J Dawson, Kathleen A Ryan, Laura M Yerges-Armstrong, Richard D Semba, Nanette I Steinle, Braxton D Mitchell, Alan R Shuldiner, Patrick F McArdle
BACKGROUND/AIMS: Alpha-carotene is a provitamin A carotenoid present in fruits and vegetables. Higher serum concentrations of α-carotene have been associated with lower risk of cancer and all-cause mortality. Previous studies have suggested that genetic variants influence serum concentrations of provitamin A carotenoids, but to date no variants have been robustly associated with serum α-carotene concentrations. The aim of this study was to identify genetic associations with serum α-carotene concentrations using the genome-wide association study (GWAS) approach...
December 22, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28002816/associations-of-serum-osteocalcin-and-polymorphisms-of-the-osteocalcin-gene-with-bone-mineral-density-in-postmenopausal-and-elderly-chinese-women
#3
Xiao-Ya Zhang, Jin-Wei He, Wen-Zhen Fu, Yu-Juan Liu, Zhen-Lin Zhang
BACKGROUND: The aims of this study were: (1) to evaluate the association of serum osteocalcin with bone mineral density (BMD) and markers of bone metabolism in postmenopausal and elderly Chinese women, and (2) to observe the relationships of single-nucleotide polymorphisms (SNPs) in and around the osteocalcin gene with osteocalcin and BMD. METHODS: A cross-sectional study was conducted with 725 postmenopausal Chinese women. Five SNPs (rs1543294, rs1800247, rs759330, rs2842880, and rs933489) of the osteocalcin gene were genotyped...
December 22, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27806373/the-genetic-predisposition-score-of-seven-obesity-related-single-nucleotide-polymorphisms-is-associated-with-better-metabolic-outcomes-after-roux-en-y-gastric-bypass
#4
Carolina Ferreira Nicoletti, Marcela A Souza Pinhel, Bruno Affonso Parenti de Oliveira, Julio Sergio Marchini, Wilson Salgado Junior, Wilson Araujo Silva Junior, Carla Barbosa Nonino
BACKGROUND/AIMS: Genetic variants associated with obesity have cumulative effects on obesity risk and related phenotypes. This study aimed to estimate the contribution of a genetic predisposition score (GPS) calculated from 7 obesity-related polymorphisms to the improvement of biochemical parameters 1 year after Roux-en-Y gastric bypass (RYGB). METHODS: Obese patients (n = 150; aged 47.2 ± 10.5 years) were enrolled and weight, body mass index (BMI), and biochemical parameters (glycemia and lipid profile) were evaluated preoperatively and 1 year after RYGB...
November 3, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27788523/association-of-neuropeptide-y-gene-rs16147-polymorphism-with-cardiovascular-risk-factors-adipokines-and-metabolic-syndrome-in-patients-with-obesity
#5
Daniel Antonio de Luis, Olatz Izaola, Beatriz de la Fuente, David Primo, Rocio Aller
BACKGROUND AND AIMS: The NPY gene has 4 exons, and it is located at 7p15.1. The main genetic variant described in this gene is rs16147. The aim of this study was to investigate the relationship of NPY rs16147 with body weight, insulin resistance, serum adipokine levels, and risk of metabolic syndrome (MetS). METHODS: A population of 1,005 obese patients was analyzed in a cross-sectional survey. Weight, fat mass, waist circumference, blood pressure, basal glucose, C-reactive protein, insulin, insulin resistance (homeostasis model assessment of insulin resistance [HOMA-IR]), lipid profile, and adipocytokine (leptin, adiponectin, and resistin) levels were measured...
October 28, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27554259/2nd-european-summer-school-on-nutrigenomics-september-5-9-2016-camerino-italy-abstracts
#6
(no author information available yet)
No abstract text is available yet for this article.
August 23, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27544754/effect-of-the-rs10767664-variant-of-the-brain-derived-neurotrophic-factor-gene-on-weight-change-and-cardiovascular-risk-factors-in-morbidly-obese-patients-after-biliopancreatic-diversion-surgery
#7
Daniel Antonio de Luis, Olatz Izaola, David Primo, David Pacheco
BACKGROUND: The effect of the rs10767664 variant of the brain-derived neurotrophic factor gene on weight loss after bariatric surgery has not been evaluated. We decided to investigate the role of the rs10767664 variant on outcomes after biliopancreatic diversion surgery. MATERIALS AND METHODS: A sample of 90 patients with morbid obesity without diabetes mellitus was operated. Biochemical and anthropometric evaluation were realized at basal visit and at each visit during 3 years (at 1, 2 and 3 years)...
August 20, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27544196/the-fto-gene-browning-of-adipose-tissue-and-omega-3-fatty-acids
#8
Artemis Simopoulos
No abstract text is available yet for this article.
August 20, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27467584/higher-fruit-intake-is-related-to-tnf-%C3%AE-hypomethylation-and-better-glucose-tolerance-in-healthy-subjects
#9
Júlia Cristina Cardoso Carraro, Helen Hermana Miranda Hermsdorff, Maria Luisa Mansego, Maria Ángeles Zulet, Fermín I Milagro, Josefina Bressan, J Alfredo Martínez
BACKGROUND/AIM: This study hypothesized an association between healthy dietary patterns, hypermethylation of the tumor necrosis factor-α (TNF-α) promoter and decreased risk of metabolic changes. METHODS: Forty normal-weight young women were involved in this cross-sectional study. DNA was isolated from white blood cells, and CpG site methylation in TNF-α was analyzed by Sequenom EpiTyper. The quality of the diet was assessed by Healthy Eating Index (HEI-2005)...
July 29, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27467525/moving-towards-specific-nutrigenetic-recommendation-algorithms-caffeine-genetic-variation-and-cardiovascular-risk
#10
Raffaele De Caterina, Ahmed El-Sohemy
Recent research has indicated that part of the interindividual variability in cardiovascular responses to caffeine has a genetic basis. Therefore, knowledge of the individual's genetic constitution may allow an individual tailoring of dietary advice for the use of caffeine-containing beverages, yielding an example of the potential of practical translation of nutrigenetic information. This paper reviews the basis for possible nutrigenetic recommendations on the consumption of caffeine, discussing the current gaps in knowledge but also proposing a mode of action in this research area, which may be transposed to other types of similar recommendations...
July 29, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27372073/association-of-lactase-persistence-genotypes-with-high-intake-of-dairy-saturated-fat-and-high-prevalence-of-lactase-non-persistence-among-the-mexican-population
#11
Claudia Ojeda-Granados, Arturo Panduro, João Renato Rebello Pinho, Omar Ramos-Lopez, Ketti Gleyzer, Fernanda de Mello Malta, Karina Gonzalez-Aldaco, Sonia Roman
BACKGROUND/AIM: Lactase (LCT) -13910 C>T and -22018 G>A polymorphisms associated with the lactase non-persistence (LNP)/persistence (LP) phenotypes vary globally. LP has been associated with obesity in Europeans. However, it has not been genetically evaluated in Mexico, a country with admixed population, recent introduction of dairy, and a high prevalence of obesity. Thus, we aimed to determine the distribution of the LCT polymorphisms and their association with the nutritional profile of West Mexico's populations...
July 2, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27318968/bovine-mammary-nutrigenomics-and-changes-in-the-milk-composition-due-to-rapeseed-or-sunflower-oil-supplementation-of-high-forage-or-high-concentrate-diets
#12
Christine Leroux, Laurence Bernard, Yannick Faulconnier, Jacques Rouel, Anne de la Foye, Jordann Domagalski, Yves Chilliard
BACKGROUND: Fatty acid (FA) composition plays a crucial role in milk nutritional quality. Despite the known nutritional regulation of ruminant milk composition, the overall mammary mechanisms underlying this regulation are far from being understood. The aim of our study was to determine nutritional regulation of mammary transcriptomes in relation to the cow milk composition. METHODS: Twelve cows received diets differing in the forage-to-concentrate ratio [high forage (HF) and low forage (LF)] supplemented or not with lipids [HF with whole intact rapeseeds (RS) and LF sunflower oil (SO)] in a 4 × 4 Latin square design...
June 18, 2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27811469/isnn-membership-application-form
#13
(no author information available yet)
No abstract text is available yet for this article.
2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27811468/isnn-society-news
#14
(no author information available yet)
No abstract text is available yet for this article.
2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27721309/10th-congress-of-the-international-society-of-nutrigenetics-nutrigenomics-isnn-may-22-26-2016-tel-aviv-israel-abstracts
#15
(no author information available yet)
No abstract text is available yet for this article.
2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27344676/issn-membership-application-form
#16
(no author information available yet)
No abstract text is available yet for this article.
2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27344600/issn-society-news
#17
(no author information available yet)
No abstract text is available yet for this article.
2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27287034/trpv1-gene-polymorphisms-are-associated-with-type-2-diabetes-by-their-interaction-with-fat-consumption-in-the-korean-genome-epidemiology-study
#18
Sunmin Park, Xin Zhang, Na Ra Lee, Hyun-Seok Jin
BACKGROUND: Different transient receptor potential vanilloid 1 (TRPV1) variants may be differently activated by noxious stimuli. AIM: We investigated how TRPV1 variants modulated the prevalence of type 2 diabetes and specific gene-nutrient interactions. METHODS: Among 8,842 adults aged 40-69 years in the Korean Genome Epidemiology Study, the associations between TRPV1 genotypes and the prevalence of type 2 diabetes as well as their gene-nutrient interactions were investigated after adjusting for the covariates of age, gender, residence area, body mass index, daily energy intake, and total activity...
2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27286972/guide-and-position-of-the-international-society-of-nutrigenetics-nutrigenomics-on-personalized-nutrition-part-2-ethics-challenges-and-endeavors-of-precision-nutrition
#19
Martin Kohlmeier, Raffaele De Caterina, Lynnette R Ferguson, Ulf Görman, Hooman Allayee, Chandan Prasad, Jing X Kang, Carolina Ferreira Nicoletti, J Alfredo Martinez
Nutrigenetics considers the influence of individual genetic variation on differences in response to dietary components, nutrient requirements and predisposition to disease. Nutrigenomics involves the study of interactions between the genome and diet, including how nutrients affect the transcription and translation process plus subsequent proteomic and metabolomic changes, and also differences in response to dietary factors based on the individual genetic makeup. Personalized characteristics such as age, gender, physical activity, physiological state and social status, and special conditions such as pregnancy and risk of disease can inform dietary advice that more closely meets individual needs...
2016: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/27169401/guide-and-position-of-the-international-society-of-nutrigenetics-nutrigenomics-on-personalised-nutrition-part-1-fields-of-precision-nutrition
#20
Lynnette R Ferguson, Raffaele De Caterina, Ulf Görman, Hooman Allayee, Martin Kohlmeier, Chandan Prasad, Myung Sook Choi, Rui Curi, Daniel Antonio de Luis, Ángel Gil, Jing X Kang, Ron L Martin, Fermin I Milagro, Carolina Ferreira Nicoletti, Carla Barbosa Nonino, Jose Maria Ordovas, Virginia R Parslow, María P Portillo, José Luis Santos, Charles N Serhan, Artemis P Simopoulos, Antonio Velázquez-Arellano, Maria Angeles Zulet, J Alfredo Martinez
Diversity in the genetic profile between individuals and specific ethnic groups affects nutrient requirements, metabolism and response to nutritional and dietary interventions. Indeed, individuals respond differently to lifestyle interventions (diet, physical activity, smoking, etc.). The sequencing of the human genome and subsequent increased knowledge regarding human genetic variation is contributing to the emergence of personalized nutrition. These advances in genetic science are raising numerous questions regarding the mode that precision nutrition can contribute solutions to emerging problems in public health, by reducing the risk and prevalence of nutrition-related diseases...
2016: Journal of Nutrigenetics and Nutrigenomics
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