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Libyan Journal of Medicine

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https://www.readbyqxmd.com/read/30045674/an-approach-to-revolutionize-cataract-treatment-by-enhancing-drug-probing-through-intraocular-cell-line
#1
Ling Wang, Weixian Liu, Xionggao Huang
The purpose of this study is to prepare and characterize solid lipid nanoparticles (SLN) of N-Acetyl Carnosine (NAC) to treat cataract since surgery necessitates equipments and professional help. Cataract is believed to be formed by the biochemical approach where the crystalline eye proteins lose solubility and forms high molecular weight masses. Added advantages of SLN of NAC (henceforth referred as SLN-NAC) in the study are reduced size, sustained release and better corneal penetration of drug. The method of preparation of SLN-NAC by Mill's method is unique in itself...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/30044720/assessment-of-vitamin-d-intake-among-libyan-women-adaptation-and-validation-of-specific-food-frequency-questionnaire
#2
Fathia Faid, Marina Nikolic, Jelena Milesevic, Milica Zekovic, Agnes Kadvan, Mirjana Gurinovic, Marija Glibetic
Vitamin D deficiency (VDD) has pandemic proportions worldwide. Numerous studies report on high prevalence of VDD in sunny regions like Near East and North Africa (NENA). Previous studies indicated that Libyan population was at risk of VDD. To contribute to the body of evidence, measurement of vitamin D status on children, adults, in Misurata region was conducted, and confirmed with validated dietary intake study. Serum 25(OH)D was analysed using electrochemiluminescence protein binding assay. Existing Food Frequency Questionnaires (FFQ) were adapted to Libyan Women Food Frequency Questionnaire (LW-FFQ)...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/30037314/modeling-the-adoption-of-personal-health-record-phr-among-individual-the-effect-of-health-care-technology-self-efficacy-and-gender-concern
#3
Bireswar Dutta, Mei-Hui Peng, Shu-Lung Sun
BACKGROUND: With the development of information technology (IT) and medical technology, medical information has been developed from traditional paper-based records into up-to-date medical information exchange system called personal health record (PHR). Empowering PHR provides health awareness and intention for health promotion. OBJECTIVE: The purpose of this study was to present a research framework to examine individuals' intention to PHR use. METHODS: This cross-sectional study used the questionnaire to collect data from the individual in Taiwan...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/30035680/roles-of-the-mst1-jnk-signaling-pathway-in-apoptosis-of-colorectal-cancer-cells-induced-by-taurine
#4
Zhuoqi Liu, Yanqin Xia, Xiali Zhang, Liqiao Liu, Shuo Tu, Weifeng Zhu, Lehan Yu, Huifang Wan, Bo Yu, Fusheng Wan
The aim of this study was to observe the impact of the mammalian sterile 20-like kinase 1-c-Jun N-terminal kinase (MST1-JNK) signaling pathway on apoptosis in colorectal cancer (CRC) cells induced by Taurine (Tau). Caco-2 and SW620 cells transfected with p-enhanced green fluorescent protein (EGFP)-MST1 or short interfering RNA (siRNA)-MST1 were treated with Tau for 48 h. Apoptosis was detected by flow cytometry, and the levels of MST1 and JNK were detected by western blotting. Compared with the control group, 80 mM Tau could significantly induce apoptosis of CRC cells, and the apoptotic rate increased with increasing Tau concentration (P < 0...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29979643/provision-of-renal-care-for-patients-with-end-stage-kidney-disease-in-persistent-vegetative-state-in-united-arab-emirates-a-national-survey-of-renal-physicians
#5
Fayez Ebrahim Alshamsi, Ahmed Chaaban, Mona Alrukhaimi, Bassam Bernieh, Omran Bakoush
Patients with end stage kidney disease (ESKD) with severely impaired cognitive function have no survival benefit from dialysis. We therefore undertook a survey to explore the renal physicians' practices of withholding and withdrawal of dialysis treatment in vegetative state patients in the United Arab Emirates (UAE). A cross sectional survey of 29 nephrology practices in UAE exploring physicians' practices in making decisions of withholding and withdrawal of dialysis treatment during provision end-of-life care for patients in persistent vegetative state (PVS)...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29943696/corporal-punishment-of-children-discipline-or-abuse
#6
Eid Bassam, Touma Boulos Marianne, Lydia Khabbaz Rabbaa, Bernard Gerbaka
INTRODUCTION: Corporal punishment is a public health problem due to its impact on the physical, psychological, and social interactions of children. OBJECTIVES: To determine the knowledge of pediatricians in Lebanon regarding corporal punishment, their preventive, educational, and legal role. METHODS: A cross-sectional descriptive study conducted on 153 pediatricians in Lebanon, by a questionnaire distributed at the 12th Annual Congress of the Lebanese Pediatric Society and the North Lebanon Pediatric Society...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29943665/application-of-automatic-statistical-post-processing-method-for-analysis-of-ultrasonic-and-digital-dermatoscopy-images
#7
Indre Drulyte, Tomas Ruzgas, Renaldas Raisutis, Skaidra Valiukeviciene, Gintare Linkeviciute
Ultrasonic and digital dermatoscopy diagnostic methods are used in order to estimate the changes of structure, as well as to non-invasively measure the changes of parameters of lesions of human tissue. These days, it is very actual to perform the quantitative analysis of medical data, which allows to achieve the reliable early-stage diagnosis of lesions and help to save more lives. The proposed automatic statistical post-processing method based on integration of ultrasonic and digital dermatoscopy measurements is intended to estimate the parameters of malignant tumours, measure spatial dimensions (e...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29927708/defining-and-grading-an-obstructive-ventilatory-defect-ovd-fev-1-fvc-lower-limit-of-normal-lln-vs-z-score-and-fev-1-percentage-predicted-pred-vs-z-score
#8
Rim Kammoun, Ines Ghannouchi, Sonia Rouatbi, Helmi Ben Saad
An obstructive ventilatory defect (OVD) is defined by a low forced expiratory volume/'forced/slow' vital capacity (FEV1 /FVC) (e.g. <lower limit of normal (LLN)). However, the LLN can be estimated either by the 90% confidence interval (or the 90th percentile) (American Thoracic and the European Respiratory Societies (ATS/ERS) method) or by the Z-score (global lung initiative (GLI) method). In 2014, a new alternative classification (GLI classification) for grading the OVD severity was proposed to replace the 2005-ATS/ERS one...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29865994/predictive-study-of-academic-stress-with-the-irritable-bowel-syndrome-in-medicine-students-at-a-public-university-in-mexico
#9
Elizabeth Pozos-Radillo, Lourdes Preciado-Serrano, Ana Plascencia-Campos, Armando Morales-Fernández, Rosa Valdez-López
BACKGROUND: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder associated with stress, which may appear by an educational context, given that students are exposed to demands in the academic environment during their education process that may lead to developing diseases. This study reports on the relationship between the IBS and academic stress and compares results of men and women. METHODS: A random survey was made of 561 medicine students at a public university in Mexico...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29865968/dietary-salt-consumption-and-the-knowledge-attitudes-and-behavior-of-healthy-adults-a-cross-sectional-study-from-jordan
#10
Izzat Alawwa, Rajaa Dagash, Akram Saleh, Abdelaziz Ahmad
High dietary sodium is recognized as a silent killer responsible for 2.3 million deaths worldwide in 2010 predominantly secondary to hypertension and its complications. Although high salt consumption is considered a worldwide public health problem, its magnitude is highly variable among different communities; therefore, it is important to study locally. This study aimed to evaluate habitual salt consumption, its important correlations, as well as the knowledge, attitude, and behavior of healthy Jordanian citizens...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29697008/incorporation-of-p-53-mutation-status-and-ki-67-proliferating-index-in-classifying-her2-neu-positive-gastric-adenocarcinoma
#11
Ayesha Ahmed, Dalal M Al-Tamimi
Her2-neu overexpression has a pathogenetic, therapeutic and a controversial prognostic role in gastric cancer. p-53 mutation status and Ki-67 proliferation index are established prognostic markers in many tumors. In this study we evaluated p-53 and Ki-67 in relation to Her2-neu positive and negative gastric adenocarcinoma (GA). This cross-sectional study was carried out at King Fahd Hospital of Imam Abdulrahman bin Faisal University. Fifty cases of GA were retrieved from pathology archives. Clinico-pathological parameters were evaluated...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29493438/is-balint-training-associated-with-the-reduced-burnout-among-primary-health-care-doctors
#12
Mirjana Stojanovic-Tasic, Milan Latas, Nenad Milosevic, Jelena Aritonovic Pribakovic, Dragana Ljusic, Rosa Sapic, Mara Vucurevic, Goran Trajkovic, Anita Grgurevic
The aim of our study was to examine whether the participation in Balint group is associated with the reducing burnout syndrome among primary health care doctors. This investigation was conducted on a population of 210 doctors employed in primary health centers in Belgrade. Out of 210 doctors, 70 have completed Balint training for a period of at least 1 year, whereas 140 doctors have never attended this training (the Non-Balint group). The level of burnout among physicians was assessed with the Serbian translation of the original 22-item version of the Maslach Burnout Inventory - Human Services Survey which defines burnout in relation to emotional exhaustion, depersonalization and personal accomplishment...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29457538/effects-of-dexmedetomidine-infusion-during-spinal-anesthesia-on-hemodynamics-and-sedation
#13
Ebru Tarıkçı Kılıç, Gaye Aydın
We evaluated the effects of intravenous dexmedetomidine during spinal anesthesia on hemodynamics, respiratory rate, oxygen saturation, sedpain, and compared them with those of saline infusion. Sixty American Society of Anesthesiologists physical status I and II cases were randomly divided into two groups. Patients were connected to the monitor after premedication, and spinal anesthesia was administered. Sensory and motor blockades were assessed using pinprick test and Bromage scale, respectively. Group I received dexmedetomidine infusion and Group II received saline infusion...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29451090/study-of-changes-in-lipid-profile-and-insulin-resistance-in-egyptian-patients-with-chronic-hepatitis-c-genotype-4-in-the-era-of-daas
#14
Ghada El Sagheer, Elwy Soliman, Asmaa Ahmad, Lamiaa Hamdy
Chronic hepatitis C virus (HCV) infection is associated with altered metabolism, including dyslipidemia and insulin resistance. These contribute to disease progression and influences the response to therapy. To investigate the relationships of new direct-acting antiviral drugs, simeprevir/sofosbuvir, with lipid profile and insulin resistance (IR). Eighty chronic hepatitis C genotype 4 patients were included; they were divided into four groups according to the severity of fibrosis as detected by fibroscan. Forty healthy persons volunteered as a control group...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29433385/intravenous-lidocaine-as-adjuvant-to-general-anesthesia-in-renal-surgery
#15
Mohamed Said Nakhli, Mohamed Kahloul, Taieb Guizani, Chekib Zedini, Ajmi Chaouch, Walid Naija
The role of intraoperative intravenous lidocaine infusion has been previously evaluated for pain relief, inflammatory response, and post-operative recovery, particularly in abdominal surgery. The present study is a randomized double-blinded trial in which we evaluated whether IV lidocaine infusion reduces isoflurane requirement, intraoperative remifentanil consumption and time to post-operative recovery in non-laparoscopic renal surgery. Sixty patients scheduled to undergo elective non-laparoscopic renal surgery under general anesthesia were enrolled to receive either systemic lidocaine infusion (group L: bolus 1...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29350104/the-importance-of-perfusion-index-monitoring-in-evaluating-the-efficacy-of-stellate-ganglion-blockage-treatment-in-raynaud-s-disease
#16
Ömer Fatih Şahin, Ebru Tarıkçı Kılıç, Yakup Aksoy, Ayhan Kaydu, Erhan Gökçek
Stellate ganglion blockage (SGB) is a method used for treating Raynaud's phenomenon (RP). This study primarily aimed to determine whether the perfusion index (PI) can be used an alternative to Horner's signs in evaluating the efficacy of SGB in patients diagnosed with RP. In a total of 40 patients, aged 18-65 years and diagnosed with primary RP, SGB was applied for 5 days on the same side with the 2-finger method, using 6 mL of 5% levobupivacaine at the 7th cervical vertebra level. The PI values were recorded from the distal end of the 2nd finger of the upper extremity on the side applied with the block at baseline and at 5, 15, 30, 60 and 120 min...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29277142/carriage-of-multidrug-resistant-bacteria-among-pediatric-patients-before-and-during-their-hospitalization-in-a-tertiary-pediatric-unit-in-tunisia
#17
Miniar Tfifha, Asma Ferjani, Manel Mallouli, Nesrine Mlika, Saoussen Abroug, Jalel Boukadida
The pandemic spread of multidrug-resistant (MDR) bacteria (i.e., methicillin-resistant Staphylococcus aureus (MRSA), extended-spectrum b-lactamase-producing Enterobacteriaceae (ESBLPE), vancomycin-resistant enterococci, carbapenemase-producing Enterobacteriaceae (CPE), multiresistant Pseudomonas aeruginosa and multiresistant Acinetobacter baumannii) pose a threat to healthcare Worldwide. We found limited data of MDR bacteria in pediatric patients hospitalized in Tunisian tertiary healthcare.The aim of the study is to evaluate the acquisition rate of MDR acquisition during hospitalization and to explore some of the associated risk factors for both carriage and acquisition at the pediatric department, Sahloul University Hospital...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29173142/sequence-analysis-of-the-n-acetyltransferase-2-gene-nat2-among-jordanian-volunteers
#18
Yazun Bashir Jarrar, Ayat Ahmed Balasmeh, Wassan Jarrar
The present study aimed to identify the NAT2 haplotypes, linkage disequilibrium, and novel NAT2 genetic variants among Jordanian population. We isolated the genomic DNA from 68 healthy, Arab, unrelated Jordanian volunteers to amplify the protein-coding region of NAT2 gene by polymerase chain reaction (PCR). Then, the amplified PCR products were sequenced using Applied Biosystems Model (ABI3730x1). It is found that the allele frequencies of known NAT2 genetic variants 191G>A, 282C>T, 341T>C, 481C>T, 590G>A, and 803A>G were 0...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/28982295/location-of-the-internal-carotid-artery-and-ophthalmic-artery-segments-for-non-invasive-intracranial-pressure-measurement-by-multi-depth-tcd
#19
Yasin Hamarat, Mantas Deimantavicius, Evaldas Kalvaitis, Lina Siaudvytyte, Ingrida Januleviciene, Rolandas Zakelis, Laimonas Bartusis
The aim of the present study was to locate the ophthalmic artery by using the edge of the internal carotid artery (ICA) as the reference depth to perform a reliable non-invasive intracranial pressure measurement via a multi-depth transcranial Doppler device and to then determine the positions and angles of an ultrasonic transducer (UT) on the closed eyelid in the case of located segments. High tension glaucoma (HTG) patients and healthy volunteers (HVs) undergoing non-invasive intracranial pressure measurement were selected for this prospective study...
December 2017: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/28971737/translation-and-cultural-adaptation-of-the-leeds-assessment-of-neuropathic-symptoms-and-signs-lanss-pain-scale-into-arabic-for-use-with-patients-with-diabetes-in-libya
#20
Sabri Garoushi, Mark I Johnson, Osama A Tashani
In Libya neuropathic pain is rarely assessed in patients with diabetes. The Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain scale is used worldwide to screen for neuropathic pain. There is no Arabic version of LANSS for use in Libya. The aim of this study was to develop an Arabic version of LANSS and to assess its validity and reliability in diabetic patients in Benghazi, Libya. LANSS was translated into Arabic by four bilingual translators and back translated to English by a university academic...
December 2017: Libyan Journal of Medicine
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