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Retinal Cases & Brief Reports

Ilya Leskov, Alexander Knezevic, Manjot K Gill
PURPOSE: To report a case of serous macular detachment in a patient with Waldenstrom macroglobulinemia treated with ibrutinib. METHODS: The patient underwent a complete ophthalmic examination and imaging at presentation and at follow-up visits up to 13 months. RESULTS: At presentation, there were serous macular detachments bilaterally with no dye leakage on fluorescein angiography or vasculature abnormalities on optical coherence tomography angiography...
December 6, 2018: Retinal Cases & Brief Reports
Yao Lu, Yimin Xu
PURPOSE: Optic disk astrocytoma is a rare variant of congenital hamartoma, which is usually associated with tuberous sclerosis complex. Generally, it is stationary but in rare cases, it can show progressive growth and cause severe local complications. METHODS: Clinical-pathologic correlation. RESULTS: A 10-year-old boy presented a unilateral optic disk mass with vitreous hemorrhage that eventually necessitated vitrectomy of the affected eye...
November 28, 2018: Retinal Cases & Brief Reports
Jeremy A Lavine, Arun D Singh, Kimberly Baynes, Sunil K Srivastava
PURPOSE: To report the multimodal imaging findings of immune recovery uveitis mimicking recurrent T-cell lymphoma after autologous bone marrow transplant therapy. METHODS: A 71-year-old man presented with posterior uveitis 6 weeks after chemotherapy and autologous bone marrow transplant for angioimmunoblastic T-cell lymphoma. Multimodal imaging included fluorescein angiography, fundus autofluorescence, and optical coherence tomography. Diagnostic testing included ocular polymerase chain reaction and diagnostic vitrectomy...
November 26, 2018: Retinal Cases & Brief Reports
Gavin Docherty, Ahmad Sidiqi, Rosanna Martens, Handan Akil, Eduardo V Navajas
PURPOSE: To describe two cases of focal choroidal excavation (FCE) conversion in patients with central serous chorioretinopathy. METHODS: Case report and literature review of cases of FCE conversion. RESULTS: A 35-year-old asymptomatic pregnant patient was found to have conforming FCE on spectral domain optical coherence tomography of the right eye during hydroxychloroquine screening. Three months later, she presented with decreased vision in the right eye and subretinal fluid in both eyes secondary to central serous chorioretinopathy...
November 26, 2018: Retinal Cases & Brief Reports
Philip G Hykin, Giovanni Staurenghi, Peter Wiedemann, Sebastian Wolf, Shiao Hui Melissa Liew, Sabine Desset-Brethes, Harry Staines, Jun Li, Timothy Y Y Lai
PURPOSE: To evaluate the efficacy and safety of ranibizumab 0.5 mg in adolescent patients with any choroidal neovascularization etiology enrolled in the 12-month MINERVA study. METHODS: In the open-label, non-randomized study arm, ranibizumab 0.5 mg was administered to five adolescents (aged 13-17 years). The findings were assessed descriptively as individual case reports at Month 12. Best-corrected visual acuity changes, central subfield thickness, treatment exposure, and safety were described over 12 months...
November 2, 2018: Retinal Cases & Brief Reports
Anina Abraham
PURPOSE: To report a case of bull's eye maculopathy probably caused by iron overload in a child with thalassemia major. METHODS: Case report. RESULTS: A 6-year-old girl with thalassemia major who was on chronic multiple blood transfusions since 2 years of age presented with blurred vision in both eyes for 2 months. Blood reports showed very high serum ferritin levels in the range 400 to 2,250 ng/mL (checked every 3 months) since 4 years of age...
November 2, 2018: Retinal Cases & Brief Reports
Benjamin Bakall, J Shepard Bryan, Edwin M Stone, Kent W Small
PURPOSE: To report a new family with North Carolina macular dystrophy including a patient with choroidal neovascularization (CNV). METHODS: Diagnostic modalities included fundus imaging, fluorescein angiography, optical coherence tomography, and genetic testing. The CNV was treated with intravitreal anti-vascular endothelial growth factor according to a treat-and-extend protocol in both eyes. RESULTS: A 60-year-old man presented with North Carolina macular dystrophy with decreasing vision in the left eye and persistently deceased central vision in the right eye...
October 31, 2018: Retinal Cases & Brief Reports
Stefano Sebastiani, Marco Pellegrini, Giuseppe Giannaccare, David Sarraf
PURPOSE: To present an atypical case of paracentral acute middle maculopathy occurred upon awakening in the morning within hours after phosphodiesterase-5 (PDE-5) inhibitor consumption at bedtime. METHODS: Multimodal retinal imaging findings, including fluorescein angiography, spectral domain optical coherence tomography, optical coherence tomography angiography, and microperimetry of a particular case of paracentral acute middle maculopathy lesion that follow the distribution of the cilioretinal artery...
October 25, 2018: Retinal Cases & Brief Reports
Errol W Chan, Vincent Sun, Mohab Eldeeb, Michael A Kapusta
PURPOSE: To describe a case of Epstein-Barr virus (EBV)-associated acute retinal necrosis (ARN) in an immunocompetent patient and to summarize the clinical features of published molecularly confirmed EBV-ARN cases. METHODS: Case report and literature review. RESULTS: An 83-year-old immunocompetent woman with unilateral ARN presented with visual acuity of light perception. Oral valacyclovir was started. One week later, vitrectomy was conducted for worsening inflammation...
October 23, 2018: Retinal Cases & Brief Reports
Leire Juaristi, Cristina Irigoyen, Jorge Quiroga
PURPOSE: To report a case of neuropathy, ataxia, and retinitis pigmentosa syndrome, a rare and undiagnosed disease in ophthalmology due to the need for multidisciplinary evaluation. METHODS: Multimodal testing was performed, including neurologic, ophthalmologic, and genetic assessments. The neurologic tests comprised electromyogram and muscle biopsy; the ophthalmologic examination consisted of slit-lamp and fundus examinations, optical coherence tomography, visual field testing, and electrophysiology tests such as a full-field electroretinogram and multifocal electroretinogram; and genetic tests were performed for spinocerebellar ataxia...
October 19, 2018: Retinal Cases & Brief Reports
Katherine G Chen, Panos G Christakis, Emily Y Chew
PURPOSE: To provide long-term, natural history data of a case of a subclinical choroidal neovascular membrane (CNVM) in the setting of age-related macular degeneration. METHODS: Retrospective review of the 10-year clinical course of a patient including multimodal imaging. RESULTS: A 75-year-old white female with macular degeneration presented with visual acuity of 20/25 in the right eye and 20/40 in the left eye. In the left eye, a retinal pigment epithelial detachment with associated subretinal and intraretinal fluid was found on spectral domain optical coherence tomography...
October 15, 2018: Retinal Cases & Brief Reports
George J Manayath, Arvind Jain, Ratnesh Ranjan, Adarsh S Naik, Vekatapathy Narendran
PURPOSE: To report a case of idiopathic full-thickness macular hole in a young boy, which was managed surgically with good visual and anatomical outcomes. METHOD: Single case report. RESULTS: An 8-year-old boy presented for defective vision in the left eye noticed for the past 2 weeks with best-corrected visual acuity of 6/24. A large full-thickness macular hole was diagnosed clinically and was confirmed on optical coherence tomography. There was no clinical or tomographic findings suggestive of trauma or retinal degeneration...
October 9, 2018: Retinal Cases & Brief Reports
Saumya M Shah, Lisa A Schimmenti, Alan D Marmorstein, Sophie J Bakri
PURPOSE: To report a case of adult-onset vitelliform macular dystrophy in a patient who was found to have a previously unreported variant of the IMPG2 gene. METHODS: Case report. RESULTS: A 65-year-old white woman with no significant medical or ocular history presented with a complaint of persistent wavy vision for 10 months. On funduscopic examination, bilateral vitelliform lesions of approximately 1 mm in the right eye and 0.5 mm in the left eye were evident, with no choroidal neovascularization in either eye...
October 8, 2018: Retinal Cases & Brief Reports
Rengin Aslıhan Kurt, Baris Sonmez, Ziya Kapran
PURPOSE: To report neurotrophic keratopathy after vitreoretinal surgery combined with aggressive photocoagulation. METHODS: We report a series of three cases with neurotrophic keratopathy after pars plana vitrectomy combined with endolaser photocoagulation. RESULTS: Three patients who had pars plana vitrectomy with different indications were identified. On follow-up, all patients were diagnosed with neurotrophic keratopathy. Two of the patients underwent amniotic membrane transplantation for the treatment of resistant neurotrophic corneal ulcers...
October 8, 2018: Retinal Cases & Brief Reports
Daniel G Cherfan, Andrew W Browne, Ryan Deasy, James Lapinski, Sunil K Srivastava
PURPOSE: To present an atypical case of syphilis that presented with findings concerning for endocarditis and valsalva retinopathy. METHODS: History and clinical examination of 42-year-old white man who presented to the emergency department with acute onset vision changes associated with gastrointestinal symptoms, otalgia, and constitutional symptoms. RESULTS: The review of this case highlights the atypical nature in which syphilis can present and can remain undiagnosed even in the face of extensive workups for other systemic conditions...
October 8, 2018: Retinal Cases & Brief Reports
Michael Colucciello
PURPOSE: To report a case of photoreceptor restitution and vision improvement with pneumatic compaction treatment of acute subfoveal hemorrhage in a patient with angioid streaks associated with pseudoxanthoma elasticum, observed by sequential fundus photography, spectral domain optical coherence tomography, and fundus autofluorescence. METHODS: Findings on initial and sequential clinical examinations, fundus autofluorescence, and spectral domain optical coherence tomography are presented, before and after pneumatic compaction, demonstrating the course of compaction and resolution of subfoveal hemorrhage and status of the foveal ellipsoid zone and external limiting membrane...
October 8, 2018: Retinal Cases & Brief Reports
Peter H Tang, Tyson R Kinnick, James C Folk, MaryAnn Mahajan, Alexander G Bassuk, Stephen H Tsang, Vinit B Mahajan
PURPOSE: To characterize the changes found in the electroretinography (ERG) recordings of patients with autosomal dominant neovascular inflammatory vitreoretinopathy and correlate with clinical stages of the disease. METHODS: Retrospective chart review. Bright- and dim-flash full-field scotopic, photopic, and 30-Hz flicker ERGs were obtained according to international standards. The scotopic ERGs were further processed to analyze the oscillatory potential. The patient described in the case report underwent full ERG testing; five patients composed the archival case series data and included scotopic ERG recordings...
October 8, 2018: Retinal Cases & Brief Reports
Ravi Parikh, Orly Gal-Or, Yoichi Sakurada, Belinda Leong, K Bailey Freund
PURPOSE: To describe the occurrence of an acquired choroidal nevus in a 73-year-old white man. METHODS: Case report. RESULTS: A 73-year-old white man was referred for an evaluation and treatment of macular changes in his left eye consistent with pachychoroid neovasculopathy. Baseline funduscopic examination and color fundus photographs showed two small peripheral choroidal nevi in the right eye and a single small choroidal nevus in the far temporal macula of the left eye...
October 3, 2018: Retinal Cases & Brief Reports
Mehmet Giray Ersoz, Mumin Hocaoglu, Isil Sayman Muslubas, Serra Arf, Murat Karacorlu
PURPOSE: To report first case of sequential development of pachychoroid pigment epitheliopathy (PPE) and central serous chorioretinopathy (CSC) after repeated intravitreal dexamethasone implantations for diabetic macular edema treatment. METHODS: We present a case of a 54-year-old man having intravitreal dexamethasone implant for bilateral diabetic macular edema. RESULTS: We observed development of pachychoroid pigment epitheliopathy, seen as a small pigment epithelial detachment on optical coherence tomography after a fourth dexamethasone implantation...
September 26, 2018: Retinal Cases & Brief Reports
Dong-Wouk Park, Brock Alonzo, Ambar Faridi, Kavita V Bhavsar
PURPOSE: Photic retinal toxicity induced by exposure to arc welding can lead to irreversible vision loss. Serial multimodal imaging is characterized in a patient with outer retinal damage secondary to welder's maculopathy. METHODS: A single case was retrospectively reviewed. RESULTS: Spectral domain optical coherence tomography acutely revealed disruption of the ellipsoid zone, hyperreflective bands through the outer nuclear layer, and outer retinal cavitation consistent with phototoxicity...
September 26, 2018: Retinal Cases & Brief Reports
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